43rd week of 2008 patent applcation highlights part 56 |
Patent application number | Title | Published |
20080262188 | SHAPE MEMORY EPOXY POLYMERS - One embodiment includes compositions of shape memory epoxy polymers. | 2008-10-23 |
20080262189 | POLYKETONE AND METHOD FOR PRODUCING THE SAME - There is provided a polyketone comprising repeating units, 95-100 mole % of which are 1-oxotrimethylene and having an intrinsic viscosity of 2.5-20 dl/g, wherein the content of Pd element is 0-20 ppm, terminal structures include an alkyl ester group (terminal group A) and an alkyl ketone group (terminal group B), and the equivalent ratio of terminal group A/terminal group B is 0.1-8.0. The polyketone of the present invention can be used in any forms, such as fibers and films, and can be applied to a wide variety of the uses such as clothing, reinforcing materials for rubbers, resins, cements, and optical fibers, electronic materials, battery materials, civil engineering materials, medical materials, daily commodities, fishery materials, and packaging materials. | 2008-10-23 |
20080262190 | Method For the Manufacture of Oligo- and Polyesters From a Mixture of Carboxylic Acid Obtained From Suberin and/or Cutin and Use Thereof - The invention relates to a method for processing mixtures of carboxylic acids obtained as hydrolysis products of suberin and cutin, particularly suberin and cutin isolated from birch bark, to give oligo- and polyesters, or corresponding ester-ethers, as well as the use of the products thus obtained as lubricants, fuel components, plasticizers, surface active agents, environmentally friendly agents for modifying wood, binders in coatings, adhesives, printing inks and composites, further in various cosmetic applications. | 2008-10-23 |
20080262191 | METHODS FOR THE PREPARATION OF IMIDES, MALEIMIDES AND MALEIMIDE-TERMINATED POLYIMIDE COMPOUNDS - Provided herein are methods for preparing maleimides, polyimides and maleimide-terminated polyimides. Specifically disclosed are methods for preparing maleimides from N-substituted maleamic acids in the presence of an alcohol catalyst and an acid co-catalyst in a solvent. Also disclosed are methods for preparing polyimides by reacting a diamine with a dianhydride in a reaction medium that includes a solvent and a polar protic co-solvent. Further provided are methods for preparing maleimide-terminated polyimides from diamines in an aromatic solvent containing a polar protic co-solvent. | 2008-10-23 |
20080262192 | Amino Group-Containing Water-Soluble Copolymer - To provide an amino group-containing water-soluble copolymer having a high chelating performance and clay dispersancy and a method of producing the amino-group containing water-soluble copolymer efficiently and with high productivity. A water-soluble polymer containing an amino group-containing monomer unit, wherein the water-soluble polymer has a molecular weight distribution of 12 or less, and a method of producing the water-soluble polymer according to any one of claims | 2008-10-23 |
20080262193 | PRODUCTION METHOD OF POLYAMIDE - In a repeated batch production of polyamide, a dicarboxylic acid component and a diamine component fed to a batch reactor are melt-polymerized in the absence of solvent. After adding the diamine component to the molten dicarboxylic acid component, the melt polymerization is further continued at a temperature equal to or higher than the melting point of polyamide being produced for at least 10 min while maintaining the pressure of the vapor phase in the batch reactor at higher than 0.1 MPaG by introducing water vapor. The polyamide thus produced is hardly affected by gels even when the melt polymerization is conducted in the presence of polyamide remaining after the previous batch production. Molded articles thereof contain little fisheyes. | 2008-10-23 |
20080262194 | POLYQUATERNIUM-1 SYNTHESIS METHODS - The present embodiments relate to a novel method of making quaternary ammonium polymers comprising the steps of: a) mixing 1,4-bis-dimethylamino-2-butene, triethanolamine, water and an acid; and b) introducing a 1,4-dihalo-2-butene to the mixture so as to initiate a reaction resulting in the quaternary ammonium polymer. | 2008-10-23 |
20080262195 | Method of preparing perfluoroalkadiene - Disclosed herein is a method of preparing a perfluoroalkadiene. A dihaloperfluorocarbon used as a starting material is added dropwise to a nonpolar organic solvent, a metal powder and an organic metal compound. The dihaloperfluorocarbon is slowly added dropwise in a temperature range from 30° C. to 150° C. for a certain period of time. Moreover, the nonpolar organic solvent used may be benzene, toluene, xylene, etc., and the organic metal compound is used by being dissolved in ethyl ether or tetrahydrofuran at a concentration of 1 to 3M. The metal powder used may be Mg, Zn, Cd, etc. | 2008-10-23 |
20080262196 | APPARATUS AND METHOD OF SEPARATING A POLYMER FROM A SOLVENT - The present invention relates to various embodiments of a system and method for separating polymer from a solvent. In one embodiment a system for separating polymer from a solvent comprises an extrusion apparatus includes a hollow member having a first end portion, a second end portion, and a feed port between the first end portion and the second end portion. The extrusion apparatus includes a back flash vent port disposed upstream of the feed port and a forward flash vent port disposed downstream of the feed port. The extrusion apparatus further includes a vent insert located at the forward flash vent port, a screw disposed inside the hollow member, and an internal superheating section disposed between the feed port and the downstream vent opening of the hollow member such that the length of the internal superheating section is greater than about four times the diameter, 4D, of the hollow member. | 2008-10-23 |
20080262197 | METHODS AND MATERIALS FOR TREATING INFLAMMATORY CONDITIONS - The invention provides methods and materials for treating inflammatory conditions. Specifically, the invention provides polypeptides, isolated nucleic acids, host cells, and methods that can be used to induce an antibody response in a mammal against an antigen such as C5 or C5a. For example, the methods and materials described herein can be used to reduce the effects of C5a within a mammal by reducing the amount of total and receptor bound C5a in the mammal. | 2008-10-23 |
20080262198 | Cross-Linkable Glycoproteins and Methods of Making the Same - Non-naturally occurring peptides/polypeptides/proteins comprising the crosslinking motif, Tyr-X-Tyr, wherein X is any amino acid, and methods of preparing the same. | 2008-10-23 |
20080262199 | Protein kinase C peptides for use in withdrawal - A method for managing withdrawal from an addictive substance is described. The method involves administering one or more peptides having specific activity for the ε and/or γ isozyme of protein kinase C (PKC). The peptide(s) can be administered prior to, concurrent with, or subsequent to administration of the addictive substance. Also described is a kit having at least one container containing a peptide having isozyme-specific activity for εPKC or γPKC and instructions for use. | 2008-10-23 |
20080262200 | Triazole Macrocycle Systems - The present invention provides novel peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production. | 2008-10-23 |
20080262201 | Method and a system for predicting protein functional site, a method for improving protein function, and a function-modified protein - The present application provides a method for predicting the functional site of a protein using data of the entire proteins of an organism of which genome data or cDNA data is known. More specifically, the present application provides a method for predicting a protein functional site, comprising the steps of calculating the frequency of occurrence of an oligopeptide in the entire proteins, calculating the value of each amino-acid residue contributing to the frequency of occurrence as the representative value of the function, and predicting the protein functional site by using the representative value of function as an indicator. The present also provides a system for predicting a functional site for automatically performing said methods. Additionally, the present application provides a method for preparing a function-modified protein comprising subjecting the amino-acid residues composing the functional site identified by the method described above to artificial mutation, and a novel thermophilic DNA polymerase prepared by the method. | 2008-10-23 |
20080262202 | NOVEL CANCER-ASSOCIATED GENES - The present invention is related to a DNA comprising a nucleotide sequence encoding a polypeptide represented by SEQ ID NO:1 or SEQ ID NO:2. The DNA according to the present invention is highly expressed in prostatic adenocarcinoma and ovarian carcinoma, and is a cancer-associated gene, so that it is possible to inhibit cancer by blocking the binding of the present protein to its ligand. Accordingly, the present antibody is used not only in the detection of the present protein, but also as an agent for the treatment or prevention of cancers such as prostatic adenocarcinoma and ovarian carcinoma. | 2008-10-23 |
20080262203 | NOVEL COMPOUNDS - The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78. | 2008-10-23 |
20080262204 | RECOMBINANT ANTIBODIES FOR THE DETECTION AND NEUTRALIZATION OF ANTHRAX TOXIN - A composition and method for treating a host having or at risk of infection by | 2008-10-23 |
20080262205 | Inhibitors of GSK-3 and crystal structures of GSK-3beta protein and protein complexes - The present invention relates to inhibitors of GSK-3 and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors and methods of utilizing those compositions in the treatment and prevention of various disorders, such as diabetes and Alzheimer's disease. In addition, the invention relates to molecules or molecular complexes which comprise binding pockets of GSK-3β or its homologues. The invention relates to a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. The invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. The invention relates to methods of using the structure coordinates to screen for and design compounds that bind to GSK-3β protein or homologues thereof. The invention also relates to crystallizable compositions and crystals comprising GSK-3β protein or GSK-3β protein complexes. | 2008-10-23 |
20080262206 | Method of Isolating Proteon Nucleation Centers from Blood and Other Biological Materials - Compositions and methods for the isolation and manipulation of misfolded, or partially misfolded, proteins present in blood and other biological materials are provided. In one aspect of the invention, the compositions, hereinafter termed “proteons” are comprised of misfolded proteins. Also provided are compositions and methods for the isolation and manipulation of proteon nucleation centers (PNCs) upon which the proteons of the present in blood and other biological materials form. In another aspect of the invention, the PNCs are comprised of metallic nanoclusters. | 2008-10-23 |
20080262207 | Benzimidazole compounds and their use as chromatographic ligands - The present invention provides a new method for isolation and/or purification of immunoglobulins from a solution containing one or more immunoglobulins using a solid phase matrix represented by the formula: M-SP-L, wherein M is designates a matrix backbone, SP designates a spacer and L designates a substituted benzimidazole ligand. | 2008-10-23 |
20080262208 | 6-11 Bridged Oxime Erythromycin Derivatives - The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: | 2008-10-23 |
20080262209 | Activated Sialic Acid Derivatives for Protein Derivatisation and Conjugation - Derivatives of PSAs are synthesised, in which a reducing and/or non-reducing end terminal sialic acid unit is transformed into a N-hydroxysuccinimide (NHS) group. The derivatives may be reacted with substrates, for instance substrates containing amine or hydrazine groups, to form non-cross-linked/crosslinked polysialylated compounds. The substrates may, for instance, be therapeutically useful drugs, peptides or proteins or drug delivery systems. | 2008-10-23 |
20080262210 | Immunostimulating Agents - Disclosed is a new type of immunostimulating agent including an immunostimulating oligonucleotide complexed with a carrier which is safe and has a high transfection effect. The carrier complexed with the immunostimulating oligonucleotide to form the immunostimulating agent is a polysaccharide having β-1,3-bonds (preferably β-1,3-glucan such as schizophyllan). A preferred example of the immunostimulating oligonucleotide is one containing an unmethylated CpG motif. The polysaccharide for use is preferably modified with nucleic acid-binding functional group and/or cell membrane-affinitive functional group. | 2008-10-23 |
20080262211 | HEPATITIS-C VIRUS TYPE 4, 5 AND 6 - The present invention relates to a polynucleic acid composition comprising or consisting of at least one polynucleic acid containing 8 or more contiguous nucleotides corresponding to a nucleotide sequence from the region spanning positions 417 to 957 of the Core/E1 region of HCV type 3; and/or the region spanning positions 4664 to 4730 of the NS3 region of HCV type 3; and/or the region spanning positions 4892 to 5292 of the NS3/4 region of HCV type 3; and/or the region spanning positions 8023 to 8235 of the NS5 region of the BR36 subgroup of HCV type 3a; and/or the coding region of HCV type 4a starting at nucleotide 379 in the core region; and/or the coding region of HCV type 4; and/or the coding region of HCV type 5, with said nucleotide numbering being with respect to the numbering of HCV nucleic acids as shown in Table 1, and with said polynucleic acids containing at least one nucleotide difference with known HCV type 1, and/or HCV type 2 genomes in the above-indicated regions, or the complement thereof. | 2008-10-23 |
20080262212 | Ribocloning: Recombinant DNA Construction using Primers with RIBO Bases - The present invention provides methods of linking nucleic acids without the use of restriction enzymes or any joining enzyme such as ligase. More specifically, the present invention provides methods for cloning or rearranging a double-stranded target DNA which is a PCR product into a double-stranded vector DNA which is a PCR product, said DNAs being amplified using primers that contain at least one ribonucleotide, preferably at or near the respective 3′ ends of the primers, such that RNA-specific cleavage, preferably by RNAse A, will allow release of the primers to create long matching 3′-sticky ends. | 2008-10-23 |
20080262213 | Processing Polynucleotide-Containing Samples - Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that regain polynucleotides under a first set of conditions (e.g., temperature and pH) and release the polynucleotides under a second set of conditions (e.g., higher temperature and/or more basic pH). The processing region can be used to, for example, concentrate polynucleotides of a sample and/or separate inhibitors of amplification reactions from the polynucleotides. Microfluidic devices with a processing region are disclosed. | 2008-10-23 |
20080262214 | Synthesis of 2-Substituted Adenosines -
A method of synthesis of a 2-substituted adenosine of formula I which comprises converting a compound of formula II to a compound of formula (I), wherein: R is C 1-6 alkoxy (straight or branched), a phenoxy group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3-, cyano, nitro, C 1-6 alkyl, or C 1-6 alkoxy), a benzoyl group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3-, cyano, nitro, C1_6 alkyl, or C1_6 alkoxy), or a benzoyl group (unsubstituted, or mono-, or di-substituted by halo, amino, CF3-, cyano, nitro, C 1-6 alkyl, or C 1-6 alkoxy); R′═H, or a protecting group. | 2008-10-23 |
20080262215 | GEMCITABINE PRODUCTION PROCESS - Provided is a process for preparing gemcitabine or a salt thereof, which preferably includes selectively precipitating the β-anomer of a 3′,5′-di-O-protected-N | 2008-10-23 |
20080262216 | HYDROXYALKYL METHYLCELLULOSE HAVING SOLUBILITY AND THERMOREVERSIBLE GELATION PROPERTIES IMPROVED - Provided is hydroxyalkyl methylcellulose which can be dissolved at room temperature of 20 to 30° C. and has high thermoreversible gel strength during thermoreversible gelation. More specifically, provided is water-soluble hydroxyalkyl methylcellulose having a molar substitution of hydroxyalkoxyl groups of 0.05 to 0.1 and a substitution degree of methoxyl groups of 1.6 to 1.9, wherein the hydroxyalkoxyl groups are classified into substituted hydroxyalkoxyl groups having hydroxyl groups of hydroxyalkoxyl groups substituted further with methoxyl groups and unsubstituted hydroxyalkoxyl groups having hydroxyl groups of hydroxyalkoxyl groups not further substituted; and a ratio (A/B) of a molar fraction (A) of the substituted hydroxyalkoxyl groups to a molar fraction (B) of unsubstituted hydroxyalkoxyl groups is 0.4 or greater. | 2008-10-23 |
20080262217 | METHOD OF PHYSICOCHEMICALLY PRODUCING GLYCOGEN AND GLYCOGEN OBTAINED BY THE SAME - A method of producing glycogen is provided. The method comprises the step of heat- and pressure-treating a sugar-containing material under acidic conditions. The sugar-containing material is a polysaccharide or an oligosaccharide. Alternatively, the sugar-containing material is a plant material selected from the group consisting of Panax notoginseng, Yun Nan San-chi powder (trademark), Panax ginseng, wheat flour, soybean, soy flour, shiitake, and coffee extract residue. Representatively, the glycogen includes a molecule having a molecular weight of 10,000 or less. The glycogen has a specific rotation of [α] | 2008-10-23 |
20080262218 | Method for Producing Sulphated Glycosaminoglycans from Biological Tissues - A method for isolating sulphated glycosaminoglycans washes a mechanically cleaned tissue, exposes tissue in a solution of 0.1M phosphate pH 5.8-6.0 buffer heated to a temperature of 65° C. for 30 minutes, overcooks the tissue in activated 0.1-0.4% papain at 65° C. for 6-24 hours, cools the papain digest to 4° C., removes fats and undigested tissue residues, selectively isolates the sulphated glycosaminoglycans for 4-10 hours on a solid carrier, obtained from bone tissue collagen with particle sizes ranging from 0-01 to 0.35 cm3, washes the carrier with 0.05-0.1 N-hydrochloric acid, degreases and eluates the carrier with a solution of 0.6-0.15 N-mineral salt in 0.8 N-acetic acid or in 0-01-0-025 N-alkali liquor, precipitates the sulphated glycosaminoglycans with ethanol, centrifuges with 1500 r.p.m. for 15 minutes at a temperature of 4° C., washes the precipitate with ethanol or acetone, and dries and sterilizes the precipitate. | 2008-10-23 |
20080262219 | NOVEL CRYSTAL OF 7-[2-[(2-AMINOTHIAZOL-4-YL)-2-HYDROXYIMINOACETAMIDE-3-VINYL-3-CEPHEM-4-CARBOXYLIC ACID (SYN ISOMER) AND METHOD FOR PREPARATION THEREOF - A novel crystal (B-type crystal) of 7-[2-(2-aminothiazol-4-yl)-2-hydroxyiminoacetamide-3-vinyl-3-cephem-4-carboxylic acid (a syn isomer) , characterized in that it exhibits peaks at diffraction angles shown in the following Table 1, in its powder X ray diffraction pattern: | 2008-10-23 |
20080262220 | POLYMORPHIC FORMS ALPHA, BETA AND GAMMA OF RIFAXIMIN - Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention. | 2008-10-23 |
20080262221 | (PYRIDO/THIENO)-[f]-OXAZEPINE-5-ONE DERIVATIVES - The present invention relates to (pyrido/thieno)-[f]-oxazepine-5-one derivatives having the general Formula I | 2008-10-23 |
20080262222 | Near infrared dyes - Near infrared (NIR) dyes, image recording substrate including the NIR dye, and methods of making the NIR dyes, are disclosed. | 2008-10-23 |
20080262223 | Isolation of Galanthamine From Biological Material - The subject matter of present invention relates to the process for isolation and purification of galanthamine and its derivatives produced by numerous plants. | 2008-10-23 |
20080262224 | Method of Preparation of Benzofuran-2-Carboxylic Acid -Amide - This invention relates to a method of preparation of benzofuran-2-carboxylic acid {(S)-3-methyl- | 2008-10-23 |
20080262225 | Use of metal complex compounds as oxidation catalysts - Use of metal complex compounds of formula | 2008-10-23 |
20080262226 | METHODS OF MAKING COMPOUNDS HAVING A BETA-ADRENERGIC INHIBITOR AND A LINKER AND METHODS OF MAKING COMPOUNDS HAVING A BETA-ADRENERGIC INHIBITOR, A LINKER AND A PHOSPHODIESTERASE INHIBITOR - A method is provided for making compounds comprising a beta-adrenergic inhibiting moiety and a linking moiety, the method comprising: a) reacting a compound of formula (A): (R | 2008-10-23 |
20080262227 | PROCESS FOR MAKING RISPERIDONE AND INTERMEDIATES THEREFOR - The formation of risperidone is enhanced by the use of enriched Z-isomer oxime intermediate(s) of formula (3) or (7). | 2008-10-23 |
20080262228 | Metabolites of 5-fluoro-8- quinoline and methods of preparation and uses thereof - The present invention relates to novel metabolites of 5-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}quinoline, which can be useful in treating CNS disorders. The present invention further relates to processes for their preparation, to pharmaceutical compositions comprising them, and to methods of using them. | 2008-10-23 |
20080262229 | Diarylmethyl Piperazine Derivatives, Preparations Thereof and Uses Thereof - Compounds of formula: | 2008-10-23 |
20080262230 | Benzyloxypropylamine Derivative - Disclosed is a novel benzyloxypropylamine derivative having an excellent tachykinin receptor antagonistic effect. This compound shows a good transfer into the blood and a long blood half-life in the blood kinetic test using a guinea pig orally administered with the compound and is stable in an animal plasma. The compound also shows a high transfer to the central nervous system when it is orally administered to a guinea pig at a certain dose. Accordingly, the benzyloxypropylamine derivative is quite useful as a novel anti-tachykinin agent. | 2008-10-23 |
20080262231 | Processes for Preparing Morphinans and Intermediates Thereof - The present invention is directed to processes for the synthesis of morphinans. In particular, a process for cyclizing a β,γ-bicyclic ketone compound to form a nordihydrothebainone product using the Grewe cyclization reaction is improved by forming a reaction mixture comprising a β,γ-bicyclic ketone compound, a cyclizing acid and a water scavenging cyclization additive. In one embodiment, the Grewe transformation occurs in the presence of an acid anhydride as the cyclization additive. Further, the present invention is directed to processes for converting α,β-bicyclic ketone compounds (e.g., by-products of the Grewe cyclization reaction) to β,γ-bicyclic ketone compounds, wherein the β,γ-bicyclic ketone compounds may be recovered to further undergo Grewe cyclization and form the nordihydrothebainone product. | 2008-10-23 |
20080262232 | PROCESSES FOR THE PRODUCTION OF POLYMORPHIC FORMS OF RIFAXIMIN - Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention. | 2008-10-23 |
20080262233 | SYNTHESIS OF PREFFERED ISOMER FRACTIONS OF N, N-DIETHYLDECAHYDROQUINOLINIUM CATION - The present invention relates to a process for synthesizing trans-N,N-diethyldecahydroquinolinium cation or a mixture of a cis-N,N-diethyldecahydroquinolinium cation and a trans-N,N-diethyldecahydroquinolinium cation. | 2008-10-23 |
20080262234 | Process for Preparing N, N-Substituted Carbamoyl Halides - The present invention relates to a new and useful process for preparing N,N-substituted carbamoyl halides from secondary amines, carbon dioxide, trialkylsilyl chloride and a halogenating agent. | 2008-10-23 |
20080262235 | Method and Apparatus for Producing Oxidized Compound - There is provided a method and an apparatus for producing an oxidized compound, which includes measuring an electric potential of an oxidation reaction solution for producing an oxidized compound by an oxidation reaction, and determining an end point of the oxidation reaction on the basis of a predefined decrease of the electric potential, thereby simply determining the end point of the oxidation reaction to swiftly move on to the next step. For example, the apparatus for producing an oxidized compound has a reactor ( | 2008-10-23 |
20080262236 | Process for the Preparation of 4-Carbonyl)Amino]Phenoxy}-N-Methylpyridine-2-Carboxamide - The present invention relates to a process for preparing 4-{4-[({[4-chloro-3-(trifluoro-methyl)phenyl]amino}carbonyl)amino]phenoxy}-N-methylpyridine-2-carboxamide and its tosylate salt. | 2008-10-23 |
20080262237 | BLACK PIGMENT, BLACK PIGMENT DISPERSION AND BLACK RESIN COMPOSITION COMPRISING THE SAME - The present invention provides a black pigment consisting of an oxonol compound having a mean particle diameter ranging from 0.01 to 10.0 micrometers, and a black pigment dispersion and a black resin composition comprising the black pigment. | 2008-10-23 |
20080262238 | Dendron and Dendrimer, Method of Producing the Same, and Method of Producing a Thioacetal Compound - A dendron or dendrimer, which has, as a recurring unit of each branch, a structure of formula (I): | 2008-10-23 |
20080262239 | Process for Producing Enantiomer of Amlodipine in High Optical Purity - The present invention relates to a process for preparation of optically pure (S)-amlodipine-L-hemitartrate DMF solvate comprising the steps of treating (R,S) amlodipine base with L-tartaric acid in the presence of dimethyl formamide and a co-solvent. The invention also relates to a process for converting (R) or (S)-amlopidine-L-hemitartrate DMF solvate into their besylates without isolating free chiral amlopidine base after solution. | 2008-10-23 |
20080262240 | Separation And Manipulation Of A Chiral Object - Among other things, to cause directional motion of chiral objects in a mixture in a chamber, a field is rotated relative, to a chamber to cause rotation of the chiral objects. The rotation of the objects causes them to move directionally based on their chirality. | 2008-10-23 |
20080262241 | Methods of Preparing Imidazole-Based Compounds - Methods of preparing imidazole-based compounds are disclosed. Particular compounds are of formula I: | 2008-10-23 |
20080262242 | Process For the Production of Carboxanilides - The present invention relates to a novel process for the preparation of a compound of general formula (I): wherein R | 2008-10-23 |
20080262243 | Beta-Sulfone Imides and Preparation Thereof - The present invention provides a novel β-sulfonimide compound having at least one imide group and at least one sulfonyl group and a method for preparing the same. | 2008-10-23 |
20080262244 | Process for the Preparation of Indolone Derivative - A process for the preparation of 4-[2-(Di-n-propylamino)ethyl]-2,3-dihydro-1H-indol-2-one of formula (I) and its pharmaceutically acceptable salts, solvates Formula I involving new intermediates of compound of formula (A) and (B) wherein R represents (i) a halogen atom selected from fluorine, chlorine atom, bromine atom and iodine atom; (ii) lower alkanesulfonyloxy group selected from methanesulfonyloxy, ethanesulfonyloxy, isopropanesulfonyloxy, propanesulfonyloxy, butanesulfonyloxy, tert-butanesulfonyloxy, pentanesulfonyloxy, hexanesulfonyloxy; (iii) substituted or unsubstantiated arylsulfonyloxy group selected from phenylsulfonyloxy, 4-methylphenylsulfonyloxy, 2-methylphenylsulfonyloxy, 4-nitrophenylsulfonyloxy, 4-methoxyphenylsulfonyloxy, 3-chlorophenylsulfonyloxy; (iv) arylalkylsulfonyloxy group selected from benzylsulfonyloxy, 2-phenylethylsulfonyloxy, 4-phenylbutylsulfonyloxy, 4- methylbenzylsulfonyloxy, 2-methylbenzylsulfonyloxy, 4-nitrobenzylsulfonyloxy, 4-methoxybenzylsulfonyloxy, 3-chlorobenzylsulfonyloxy. | 2008-10-23 |
20080262245 | Process for the Preparation of Amorphous Fluvastatin Sodium - The present invention relates to a novel process for the preparation of the HMG-CoA reductase inhibitor, fluvastatin, more specifically to a process for the preparation of amorphous form of fluvastatin sodium. | 2008-10-23 |
20080262246 | 3-Alkyl-5- (4-Alkyl-5-Oxo-Tetrahydrofutr An -2-Yl) Pyrrolidin-2-One Derivatives As Intermediates In The Synthesis Of Renin Inhibitors - The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula II, | 2008-10-23 |
20080262247 | Process for preparing arylaminopropanols - The invention relates to a process for preparing enantiomerically enriched arylaminopropanols and to their use and also to intermediates. | 2008-10-23 |
20080262248 | Photochromic Spirodihydrophenanthropyrans - Specific photochromic spirodihydrophenanthropyrans and their use in synthetic resin materials of all kinds, particularly for ophthalmic purposes. The compounds of the invention are photochromic pyran compounds derived from 9,10-dihydrophenanthrene in which at least one of the two carbon atoms at positions 9 and 10 belongs to a further ring system and thus forms a spiro linkage point. | 2008-10-23 |
20080262250 | Semi-Synthesis of Taxane Intermediates and Their Conversion to Paclitaxel and Docetaxel - A process is provided for the semi-synthesis of taxane intermediates useful in the preparation of paclitaxel and docetaxel, in particular, the semi-synthesis of protected taxane intermediates. | 2008-10-23 |
20080262251 | Process For the Recovery of Sterols From Organic Material - A process for recovering sterols from organic material containing sterols and sterol derivatives. In a first step (a) the organic material is reacted with at least one of polyols, polyamines, alkanolamines or monohydric alcohols to increase the amount of free sterols in the organic material; (b) reacting residual reactants, and their esters or amides with epoxydated components; and (c) separating the free sterols from the mixture by short path distillation, thin film evaporation, or flash evaporation. The recovered sterols can be further purified by a crystallization step. | 2008-10-23 |
20080262252 | Oxidation-stabilized oily liquids based on vegetable or animal oils - The present invention provides oily liquids comprising
| 2008-10-23 |
20080262253 | Method for Purification of Botanical Oil Without Producing any Trans Fatty Acid as By-Product and Apparatus for the Method - Disclosed is a method for producing botanical oil with no by-produced trans fatty acids comprising the steps of;
| 2008-10-23 |
20080262254 | Sphingolipids - The use of a metathesis catalyst in the preparation of a functionalized sphingolipid. | 2008-10-23 |
20080262255 | STABILIZED VEGETABLE OILS AND METHODS OF MAKING SAME - A method for modifying ethylenic unsaturation in a triglyceride. One or more unsaturated fatty acyl moieties present in the triglyceride are substituted with a lactone or ketone moiety via a electron acceptor mediated reaction. The resulting reaction products are useful, for example, as lubricants, metalworking fluids, mold release agents, hydraulic fluids, or dielectric fluids, or as components of lubricants, metalworking fluids, mold release agents, hydraulic fluids, or dielectric fluids, and intermediates for polymer synthesis. | 2008-10-23 |
20080262256 | Method for Efficiently Producing Methyltrioxorhenium(VII) (Mto) and Organorhenium (VII) Oxides - The present invention relates to a novel process for preparing organorhenium(VII) oxides. | 2008-10-23 |
20080262257 | MANUFACTURING METHOD OF ORGANOBORON COMPOUND - A manufacturing method for one of, or a mixture of, an optically active allylboron compound and racemic or optically active boryl cyclopropane, including a coupling reaction, in the presence of a catalyst, between allyl compound and diboron compound. It is preferred that a copper (I) complex is used as the catalyst. It is preferred that a counterion of the copper (I) complex is an alkoxide or a hydride. It is preferred that the copper (I) complex has a phosphine ligand. It is preferred that the phosphine ligand is a chiral phosphine ligand. | 2008-10-23 |
20080262258 | Container For Forming Self-Baking Electrodes - A container for forming an electrode that can be used in electric reduction furnaces. The container comprises a cylindrical casing. Within the cylindrical casing is a plurality of ribs attached along the inner surface of the casing lengthwise of the cylindrical casing. At least one of the ribs in the container is made of a material comprising copper. | 2008-10-23 |
20080262259 | Method for vegetable oil derived polyols and polyurethanes made therefrom - A process for preparing natural oil hydroxylates, the process comprising reacting an amino compound containing hydroxyl groups having a molecular weight of less than 200 Daltons with vegetable oil derived polyols. | 2008-10-23 |
20080262260 | Method for stabilizing Menthyl Lactate - A method for stabilizing menthyl lactate is disclosed. The method comprises combining water with a solution comprising menthyl lactate and a water-miscible organic solvent in amounts effective to precipitate menthyl lactate from the resulting aqueous mixture. The aqueous precipitation method is simple to practice, and it provides menthyl lactate having remarkably improved storage stability. | 2008-10-23 |
20080262261 | STABLE LIQUID BIURET MODIFIED AND BIURET ALLOPHANATE MODIFIED TOLUENE DIISOCYANATES, PREPOLYMERS THEREOF, AND PROCESSES FOR THEIR PREPARATION - This invention relates to stable liquid biuret modified toluene diisocyanates, prepolymers thereof, stable liquid biuret allophanate modified toluene diisocyanates, prepolymers thereof, and to processes for the preparation of these compositions. The stable liquid biuret modified toluene diisocyanates comprise a secondary amine based biuret modified TDI having an NCO group content of about 12 to about 46% by weight. | 2008-10-23 |
20080262262 | Preparation of polyisocyanates containing uretdione groups using phosphine catalysts - The invention provides a process for isocyanate dimerization (uretdione formation) and a process for preparing polyisocyanates having a high content of uretdione groups, using specific phosphines as catalysts. The phosphines have one or two tertiary alkyl radicals bound directly to phosphorus. | 2008-10-23 |
20080262263 | Method For Purifing Residues Containing Isocyanates - The present invention comprises a process for purifying isocyanate-comprising residues. | 2008-10-23 |
20080262264 | Process For the Preparation of Sulfomate-Carboxylate Derivatives - Disclosed is a process for the preparation of Compound (III), salt or solvate thereof by reacting Compound (I), salt or solvate thereof with Compound (II) in a toluene solvent in the presence of an additive such as water or an alcohol. Also disclosed is a process for the preparation of Compound (IV) comprising hydrolyzing the obtained Compound (III) if necessary, and then oxidizing. | 2008-10-23 |
20080262265 | CONTINUOUS PROCESS FOR THE PREPARATION OF ALKYLENEIMINES - A process for the preparation of alkyleneimines by subjecting sulfuric acid monoesters of aminoalkanols to an at least two-stage reaction with aqueous bases at a temperature of at least 110° C. under pressure, relieving the pressure of the reaction mixture and distilling off the alkyleneimines from the reaction mixture after each reaction stage, wherein the conversion in the first stage is from 40 to 90% and that in the second stage is from more than 90% to 99.99%. | 2008-10-23 |
20080262266 | Method for the Production of Xylyendiamine - Process for preparing o-, m- or p-xylylenediamine by hydrogenation of o-, m- or p-phthalonitrile in the presence of a heterogenous catalyst, which comprises feeding a solution of the phthalonitrile in the corresponding isomer of crude xylylenediamine into the hydrogenation reactor, with the crude xylylenediamine having a purity in the range from 85 to 99.7% by weight and a content of higher boilers in the range from 0.3 to 15% by weight. | 2008-10-23 |
20080262267 | NOVEL PROCESS - The present invention relates to processes for the preparation of 4-hydroxy-α′-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol 1-hydroxy-2-naphthoate (salmeterol xinafoate) (12a), the preparation of 4-hydroxy-α′-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (salmeterol) (11), the preparation of protected N-[6-(4-phenylbutoxy)hexyl]amine intermediates (7), and the preparation of 6-substituted (4-phenylbutoxy)hexane intermediates (5), shown below, wherein X is a leaving group and Pg is a protecting group. | 2008-10-23 |
20080262268 | Crystallization Method for Benzphetamine - There is disclosed a method for the crystallization of benzphetamine hydrochloride from an organic medium by the steps of removing water from the system to a very low level and then reducing the temperature of the organic medium to provide crystallization of the acid salt. In the event that crystallization does not occur upon lowering the temperature of the medium, it has been discovered that gentle heating of the organic medium results in crystallization of the acid salt. It has also been discovered that higher temperature crystallization has been provided by removal of methamphetamine from the composition. The crystalline benzphetamine hydrochloride can then be isolated by typical liquid/solid separation means such as filtration or centrifugation. | 2008-10-23 |
20080262269 | Monodonor Phosphonite Ligands - The invention provides the use of a metal complex, which is a complex of one or more metal atoms or ions with one or more ligands, as a catalyst in an organic transformation selected from hydrogenation of carbon-heteroatom double bonds, hydroformylation, dialkylzinc additions to aldehydes, hydrocarboxylation, allylic substitution, oxidation, epoxidation, dihydroxylation, Diels-Alder cycloadditions, dipolar cycloadditions and rearrangement reactions, wherein one or more of the ligands is a ligand of formula (1), wherein the bridge group is an organic functional group, and the R group is a substituted phenyl group, wherein the R group has only one substituent at the ortho position, and wherein a carbon atom of the R group bonds the R group to the P atom. Also provided are monodonor ligands of formula (1) wherein the bridge group is an unsubstituted or substituted binaphthyl group and the R group is a substituted phenyl group, wherein the substituents are selected from halogen, nitro, alkynyl and sulfonic acid groups and unsubstituted or substituted alkyl, aryl, amino and vinyl groups, and wherein the R group has only one substituent at the ortho position, and wherein a carbon atom of the R group bonds the R group to the P atom. | 2008-10-23 |
20080262270 | CATALYST FOR THE PREPARATION OF METHYL MERCAPTAN - The present invention refers to a catalyst for the manufacture of methyl mercaptan from carbon oxides comprising Mo and K compounds and oxides or sulfides of metals chosen from the manganese group. The improvement of the present process consists of the fact that carbon dioxide can be converted with higher conversions and selectivities to methyl mercaptan as compared to state-of-the-art technologies, with only minor amounts of carbon monoxide being formed as side product. Simultaneously, carbon monoxide can be easily converted into carbon dioxide and hydrogen by reaction with water using established water-gas-shift-technologies thus increasing the overall selectivity to methyl mercaptan. | 2008-10-23 |
20080262271 | C10 Dialdehyde, Synthetic Method Thereof, and Synthetic Method of Beta-Carotene Using the Same - The novel intermediate compound which can be efficiently utilized in the synthesis of carotenoid compounds based on the sulfone chemistry, the preparation method of the same, and the practical synthetic process for preparing β-carotene by the use of the above novel compound are disclosed. The synthesis of β-carotene is characterized by the double elimination reactions of the C | 2008-10-23 |
20080262272 | Method For Producing Ethers - A method for producing ethers comprises the following steps: | 2008-10-23 |
20080262273 | Method for Producing Hydrate of Fluoroalkyl Ketone - The present invention relates to a method for producing a compound represented by formula (2): | 2008-10-23 |
20080262274 | PROCESSES FOR PRODUCING CHLOROFLUOROCARBON COMPOUNDS USING INORGANIC FLUORIDE - Methods and systems for producing chlorofluorocarbon with an inorganic fluoride (e.g., germanium tetrafluoride (GeF | 2008-10-23 |
20080262275 | PROCESSES FOR PRODUCING HALOCARBON COMPOUNDS USING INORGANIC FLUORIDE - Methods and systems for producing halocarbon with an inorganic fluoride (e.g., germanium tetrafluoride (GeF | 2008-10-23 |
20080262276 | PROCESSES FOR PRODUCING HYDROFLUOROCARBON COMPOUNDS USING INORGANIC FLUORIDE - Methods and systems for producing hydrofluorocarbon with an inorganic fluoride (e.g., germanium tetrafluoride (GeF | 2008-10-23 |
20080262277 | PROCESSES FOR PRODUCING HALOGENATED HYDROCARBON COMPOUNDS USING INORGANIC FLUORIDE - Methods and systems for producing halogenated hydrocarbon compounds with an inorganic fluoride (e.g., germanium tetrafluoride (GeF | 2008-10-23 |
20080262278 | Integrated Process for Producing Xylenes and High Purity Benzene - Processes and apparatus are provided that provide high yields of xylenes per unit of aromatic-containing feed while enabling a high purity benzene co-product to be obtained without the need for an extraction or distillation to remove C | 2008-10-23 |
20080262279 | Production of Alkylaromatic Compounds - A process for producing a monoalkylation aromatic product, such as ethylbenzene and cumene, utilizing an alkylation reactor zone and a transalkylation zone in series or a combined alkylation and transalkylation reactor zone. This process requires significantly less total aromatics distillation and recycle as compared to the prior art. | 2008-10-23 |
20080262280 | Integrated process for producing xylenes and high purity benzene - Processes and apparatus are provided that provide high yields of xylenes per unit of aromatic-containing feed while enabling a high purity benzene co-product to be obtained without the need for an extraction or distillation to remove C | 2008-10-23 |
20080262281 | Catalyst Used for the Oxidation of Hydrogen, and Method for the Dehydrogenation of Hydrocarbons - A catalyst for the oxidation of hydrogen in a process for the dehydrogenation of hydrocarbons, wherein the catalyst comprises, supported on α-aluminum oxide, from 0.01 to 0.1% by weight of platinum and from 0.01 to 0.1% by weight of tin, based on the total weight of the catalyst, a process for the oxidation of hydrogen and a process for the dehydrogenation of hydrocarbons with an integrated oxidation process using the catalyst described. | 2008-10-23 |
20080262282 | Method for Producing Paraxylene Comprising an Adsortion Step and Two Isomerization Steps - A process for producing para-xylene from a hydrocarbon feed is described in which an adsorption column operating as a simulated moving bed with at least five zones delivers an extract, a 2-raffinate and an intermediate raffinate. | 2008-10-23 |
20080262283 | Process for the removal of hydrocarbons from soils - A method of removing hydrocarbons from soils contaminated with various hydrocarbons such as gasoline, diesel fuel, solvents, motor oil and crude oil. The process first screens the soil to remove oversized rocks and debris and to reduce the contaminated soil to uniformly sized particles. The soil particles are moved along a conveyor and first sprayed with an oxidizer diluted with ionized water and then sprayed with ionized/oxidized water. The washed particles are then vigorously mixed with an auger mixer for several minutes to oxidize almost all of the remaining hydrocarbons. The washed and hydrocarbon-free soil is then moved by conveyor to a stockpile for storage, testing and drying. | 2008-10-23 |
20080262284 | DISPOSAL SYSTEM FOR TRANSDERMAL DOSAGE FORM - The present invention relates to a disposable article to prevent the misuse of a transdermal dosage form (FIG. | 2008-10-23 |
20080262285 | Method for removing phosphate from aqueous solutions - A method for removing phosphate ion from an aqueous solution containing phosphate ion using a resin loaded with a hydrous oxide of an amphoteric metal ion. The resin loaded with a hydrous oxide of an amphoteric metal ion is produced by combining a resin with at least two bed volumes of an aqueous solution containing a salt of the amphoteric metal ion, and having a metal ion concentration of at least 5%, and then treating with an aqueous alkali metal hydroxide solution. | 2008-10-23 |
20080262286 | SPECIFIC INHIBITION OF CPLA2 ENHANCES THE EFFICACY OF RADIOTHERAPY - A method for increasing the radiosensitivity of a target tissue in a subject is disclosed. In some embodiments, the methods includes administering a cytosolic phospholipase A2 (cPLA | 2008-10-23 |
20080262287 | System for delivery of magnetic stimulation - A system for delivering magnetic stimulation to a subject that has a magnetic stimulation coil, a power source, and a patient-positioning device is provided. The magnetic stimulation coil is movably connected to patient-positioning device for fixably positioning the magnetic stimulation coil to stimulate a region of a subject and electrically connected to the power source. A cooling system maintains the magnetic stimulation coil between a temperature of about 5° C. and about 40° C. during operation of the coil for a period of at least 90 minutes. An attachment site for a second magnetic stimulation coil is provided, and the second magnetic stimulation coil is optionally movably connected to the patient-positioning device for positioning the second magnetic stimulation coil independently of the first magnetic stimulation coil to provide a combination delivery of magnetic stimulation to a second region of the subject. | 2008-10-23 |
20080262288 | Physiologic pulsatile pump - A pulsatile blood circulating pump system that is adapted for use in cardiopulmonary bypass, ventricular assist (LVAD, RVAD, BiVAD), ECMO, organ preservation, fetal cardiac bypass, cancer treatment, and various areas of circulation research, which can be controlled in such a way as to produce a desired blood flow that closely approximates the physiological blood flow of the patient. The pump system includes a pulsating mechanism having a housing defining a chamber within which a compressible-expandable bladder is sealably mounted. The system further includes a hydraulic actuator having a pressure imparting member that acts upon a pressure transmissive fluid contained within the actuator chamber in a manner to generate a pulsatile pressure on the transmissive fluid, which, in turn, results in a pulsatile pressure being exerted on bladder in a manner to controllably vary the volume thereof. Additionally, the system includes a compact, highly reliable voice-coil motor that is operably associated with the hydraulic actuator for controllably moving the pressure imparting member within the fluid chamber and further includes a fully programmable motion controller that controls the voice-coil motor. Further, the system includes a programmable touch-screen component that functions to control the motion controller. | 2008-10-23 |