| 42nd week of 2008 patent applcation highlights (10-16-08/10-16-08_49) part 49 |
| Patent application number | Title | Published |
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| 20080255338 | Method of batch falling strand devolatilizer - A design method of batch falling strand devolatilizers is disclosed. The method includes following steps. Firstly, construct a database that contains data of batch falling strand devolatilizer vs. devolatilization of at least one kind of polymer. Then data in the database is substituted into a mass balance difference equation to get a backmixing parameter. When the backmixing parameter is zero or is approaching zero, a liquid diffusion stage efficiency equation having a film equation or a pool equation is integrated with the mass balance difference equation to get a devolatilization process efficiency equation. By means of a theoretical value of the backmixing parameter, a theoretical value of the process efficiency from calculation of the devolatilization process efficiency equation approaches the value of the process efficiency. Then the theoretical value of the backmixing parameter is substituted into the devolatilization process efficiency equation for performing volume design of the batch falling strand devolatilizer. | 10-16-2008 |
| 20080255339 | Chimeric proteins with cell-targeting specificity and apoptosis-inducing activities - The present invention relates to chimeric proteins with cell-targeting specificity and apoptosis-inducing activities. In particular, the invention is illustrated by examples of chimeric proteins including recombinant chimeric proteins between a gonadoptropin releasing hormone (GnRH) and an apoptosis-inducing moiety, such as a pro-apoptotic member of Bcl-2 family, such as Bik, Bax and Bak, or caspases, such as caspase-3. The chimeric proteins specifically target cells expressing a GnRH-binding site, such as adenocarcinoma cells, and induce cell-specific apoptosis. | 10-16-2008 |
| 20080255340 | ANGIOGENIN COMPLEXES (ANGex) AND USES THEREOF - Stabilized angiogenin compositions and methods of preparing a stabilized angiogenin compositions by non-covalent immobilization on a naturally occurring substrate, such as a protein, lipid, nucleic acid or nucleotide substrate, are disclosed. | 10-16-2008 |
| 20080255341 | ASSAY METHOD FOR GROUP TRANSFER REACTIONS - The present invention relates to methods for detecting, quantifying and high throughput screening of donor-products and the catalytic activities generating the donor-products in group-transfer reactions. The invention further provides immunoassays, antibodies and kits that may be used to practice the methods of the invention. | 10-16-2008 |
| 20080255342 | PROTEIN PURIFICATION METHOD - A method for removing contaminant DNA in a sample containing a physiologically active protein, which comprises the following steps:
| 10-16-2008 |
| 20080255343 | CHIMERIC ANTIBODIES - The present invention provides a chimeric antibody or an antigen-binding portion thereof. The antigen-binding portion comprises at least two complementarity determining regions (CDR) and at least three framework regions, wherein at least one CDR is a New World primate CDR | 10-16-2008 |
| 20080255344 | Immuno-Adsorbers For Treatment of Inflammations - The invention relates to an immunological adsorber for treating inflammations, in particular for eliminating complement factors, and, optionally, additional sepsis-mediators, such as, TNF and interleukins from body fluids. The invention also relates to a method for the production and use of said immunological adsorber. The aim of the invention is to develop a modular immunoadsorption system, in particular for extracorporal detoxification, which enables plasma and tissue levels, which are specific to the patient, to be reduced. The inventive immunological adsorber consists of organic or synthetic polymer support materials whereon polyclonal and monoclonal antibodies are connected which are oriented counter to the complement factor C3a and/or C5a. In a preferred embodiment, other antibodies which are oriented counter to the additional inflammation mediators, are connected to the support. In a particularly advantageous embodiment, the invention relates to an immunoadsorber provided with antibodies against C5a and IL6. | 10-16-2008 |
| 20080255345 | IRNA Agents Targeting CCR5 Expressing Cells And Uses Thereof - The invention relates to iRNA agents that preferably include a modification that targets CC chemokine receptor 5 (CCR5). The invention also relates to methods of making and using such modified iRNA agents. | 10-16-2008 |
| 20080255346 | Ratiometric fluorescent chemosensor for selective detection of Hg (II) ions - A mercury selective fluorescent chemosensor for detecting mercury ions (Hg | 10-16-2008 |
| 20080255347 | Process for making galantamine - A novel process for the preparation of N-methyl-N-(2-[4-hydroxyphenyl]ethyl)-5-hydroxy-4-methoxy benzene carboxamide, which is useful as an intermediate in the synthesis of (−)-galantamine, comprises the reaction of a 5-hydroxy-4-methoxy benzoic acid derivative with N-methyl-N-(2-[4-hydroxyphenyl]ethyl)amine. | 10-16-2008 |
| 20080255348 | METHOD FOR THE PREPARATION OF AN ENANTIOMER OF A TETRACYCLIC BENZAZEPINE - The present invention relates to a method for the preparation of mirtazapine and tetracyclic analogous compounds having substantial enantiomeric excess of the R or S form. The invention further relates to a novel intermediate and its use for the preparation of mirtazapine having a substantial enantiomeric excess of the R or S form. The method comprising the steps of a: providing a carboxylic acid compound according to Formula I having a substantial enantiomeric excess of the R or S form, b: converting the carboxylic acid group of compound I into a ketone group, producing a ketone compound of Formula II, c: optionally reducing ketone compound II with a mild reduction agent to form the intermediate hydroxy compound of Formula III and d: forming the mirtazapine of Formula IV by reduction of the ketone compound II or of the hydroxy compound III using a strong reduction agent. | 10-16-2008 |
| 20080255349 | METHOD FOR THE PREPARATION OF AN ENANTIOMERICALLY PURE BENZAZEPINE - The invention relates to a method for the preparation of a cyclic compound according to formula III comprising reacting a compound according to Formula I and a compound according to formula II, | 10-16-2008 |
| 20080255350 | SUBSTITUTED AZA-INDOLES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) - The present invention relates to a series of substituted aza-indole derivatives of the formula I: | 10-16-2008 |
| 20080255351 | Method for Preparing Aminodiglycol (Adg) and Morpholine - Processes comprising: providing a starting material comprising diethylene glycol; and reacting the starting material with ammonia in the presence of a heterogeneous transition metal catalyst to form a reaction product comprising aminodiglycol and morpholine; wherein the catalyst comprises a catalytically active composition, which prior to treatment with hydrogen, comprises a mixture of oxygen-containing compounds of copper, nickel, cobalt and at least one of aluminum and zirconium; and wherein the catalyst is present as one or more shaped catalyst particles selected from spheres, extrudates, pellets and other geometries, wherein the sphere or extradate has a diameter of <3 mm, the pellet has a height of <3 mm, and the other geometries have an equivalent diameter L=1/a′ of <0.70 mm, where a′ is the external surface area per unit volume (mm | 10-16-2008 |
| 20080255352 | Cyclic amide derivative, and its production and use - The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I): | 10-16-2008 |
| 20080255353 | METHOD FOR PREPARING MELAMINE SALT OF BIS(PENTAERYTHRITOL PHOSPHATE) PHOSPHORIC ACID - A method for producing a melamine salt of bis(pentaerythritol phosphate) phosphoric acid is proposed. The method includes the steps of reacting and mixing pentaerythritol and diphosphorous pentaoxide in an extruder to carry out esterification to produce bis(pentaerythritol phosphate) phosphoric acid; and mixing bis(pentaerythritol phosphate) phosphoric acid with melamine or a derivative thereof to carry out quaternization in the presence of a solvent, followed by removing water to obtain a melamine salt of bis(pentaerythritol phosphate) phosphoric acid. Diphosphorous pentaoxide is used in the method as a reactant, so that no hydrogen chloride is produced and it is not necessary to recollect trichlorophosphoric acid. Moreover, in the method of the present invention, such that esterification time can be shortened and a high pressure in a closed reaction system that causes explosion can be avoided. | 10-16-2008 |
| 20080255354 | Method for Producing Alkoxysilyl Methyl Isocyanurates - Alkoxysilylmethyl isocyanurates are prepared in high space time yield by reaction of a chloromethylalkoxysilane with a metal isocyanate in the presence of a tetrakis[hydrocarbon]ammonium phase transfer catalyst, with minimal formation of byproducts. | 10-16-2008 |
| 20080255355 | Chiral Diphosphonites as Ligands in the Ruthenium-Catalyzed Enantioselective Reduction of Ketones, B-Ketoesters and Ketimines - Chiral ruthenium complexes are disclosed, obtained by reaction of a ruthenium salt with a chiral diphosphonite. Chiral diols with the general structure given in scheme | 10-16-2008 |
| 20080255356 | CHIRAL TERTIARY AMINOALKYLNAPHTHOLS - The present invention provides bipyrimidinyl diphosphine compounds of the formula | 10-16-2008 |
| 20080255357 | Terrylene and Quaterrylene Derivatives - Rylene derivatives of the general formula I | 10-16-2008 |
| 20080255358 | Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases - Disclosed are imidazopyridine compounds having the formula: | 10-16-2008 |
| 20080255359 | Novel Chemical Process For the Synthesis of Quinoline Compounds - Disclosed is a novel, simplified and economic process for making 3-phenylsulphonyl quinolines with an amine group at position 8 of the quinoline ring system, including 3-phenylsulfonyl-8-piperazin-1-yl-quinoline in particular, in the absence of a palladium catalyst. Also disclosed is the crystallization of polymorphic forms of 3-phenylsulfonyl-8-piperazin-1-yl-quinoline. | 10-16-2008 |
| 20080255360 | Process for Producing Ethyleneamines - Processes comprising: providing a starting material comprising monoethanolamine; and reacting the starting material with ammonia in the presence of a heterogeneous transition metal catalyst to form a reaction product comprising one or more ethylene amines; wherein the catalyst comprises a catalytically active composition, which prior to treatment with hydrogen, comprises a mixture of oxygen-containing compounds of aluminum, copper, nickel and cobalt; and wherein the catalyst is present as one or more shaped catalyst particles selected from spheres, extrudates, pellets and other geometries, wherein the sphere or extrudate has a diameter of <3 mm, the pellet has a height of <3 mm, and the other geometries have an equivalent diameter L=1/a′ of <0.70 mm, where a′ is the external surface area per unit volume (mm | 10-16-2008 |
| 20080255361 | Process for Producing Ortho-Metalated Complex of Iridium With Homoligand - Disclosed is a process for producing an ortho-metalated 1:3 complex of iridium with homoligands which is useful as a luminous material for an organic EL device in high yield at high purity in a short time by a simple procedure. An example of the complex is tris(2-phenylpyridine)iridium(III) and this complex can be produced by reacting iridium(III) acetylacetonate with an organic ligand consisting of 2-phenylpyridine in the copresence of an acidic substance, either an organic acid such as tartaric acid or an inorganic acid such as phosphoric acid. | 10-16-2008 |
| 20080255362 | Cyclic amide derivative, and its production and use - The present invention provides a cyclic amide derivative useful as a drug for treating thrombosis, which is represented by the formula (I): | 10-16-2008 |
| 20080255363 | Novel Form of S-Omeprazole - The present invention relates to a novel form of the (−)-enantiomer of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole, i.e. S-omeprazole. More specifically, it relates to a novel form of the magnesium salt of the S-enantiomer of omeprazole trihydrate. The present invention also relates to processes for preparing such a form of the magnesium salt of S-omeprazole and pharmaceutical compositions containing it. Furthermore, the present invention also relates to new intermediates used in the process. | 10-16-2008 |
| 20080255364 | Method For The Production A-Chloroalkylpyridyl Ketones And/Or The Hydrochlorides Thereof - Process for preparing unsubstituted or nuclear-substituted α-chloroalkyl pyridyl ketones and/or their hydrochlorides by reacting the corresponding unsubstituted or nuclear-substituted alkyl pyridyl ketone hydrochlorides with sulfuryl chloride at a reaction temperature of from −25 to 70° C. (248 to 343 K) and a pressure of 0.05 to 0.2 MPa abs, in which the reaction is carried out in the presence of an unbranched or branched C | 10-16-2008 |
| 20080255365 | Microparticulate form of a Tetrahydropyridine derivative - The invention relates to a microparticulate form of 1-[2-(2-naphthyl)-ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride consisting of particles for which at least 55% of the population have a diameter below 50 micrometers, and to pharmaceutical compositions in which it is present. | 10-16-2008 |
| 20080255366 | Crystalline Trihydrate of Zoledronic Acid - Zoledronic acid trihydrate, processes for its preparation, and conversion into zoledronic acid monohydrate. | 10-16-2008 |
| 20080255367 | Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates - The present invention discloses processes for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane-carboxylates. | 10-16-2008 |
| 20080255368 | Tgf-ß Gene Expression Inhibitor - A TGF-β gene expression inhibitor containing a pyrrole-immidazole polyamide comprising an N-methylpyrrole unit (hereinafter also referred to as Py), an N-methylimidazole unit (hereinafter also referred to as Im) and a γ-aminobutyric acid unit which can be folded into an U-shaped conformation at the above-described γ-aminobutyric acid unit site in a minor groove of a double-stranded region (hereinafter referred to as the target region) containing a part or the whole of the following base sequence (SEQ ID NO: 2) corresponding to −450 to −310 of human transforming growth factor β1 (hereinafter also referred to as h TGF-β1) promoter and a strand complementary thereto and in which a Py/Im pair, an Im/Py pair and a PY/Py pair correspond respectively to a C-G base pair, a G-C base pair and an A-T base pair and a T-A base pair. | 10-16-2008 |
| 20080255369 | Synthesis of Renin Inhibitors Involving a Cycloaddition Reaction - The invention related to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, especially renin inhibitors, such as Aliskiren. Inter alia, the invention relates to a process for the manufacture of a compound of the formula III, | 10-16-2008 |
| 20080255370 | SINGLE CARBON PRECURSOR SYNTHONS - The chemistry of [ | 10-16-2008 |
| 20080255371 | Method for improving optical purity of 1-benzyl-3-aminopyrolidine and salt for use therein - The present invention provides a method to improve the optical purity of 1-benzyl-3-aminopyrrolidine having a low optical purity using an inexpensive agent via a simple procedure. The present invention provides a method for improving the optical purity of 1-benzyl-3-aminopyrrolidine including the steps of converting 1-benzyl-3-aminopyrrolidine into an equimolar salt with an optically inactive acid, and recovering the salt as crystals. The present invention also provides a salt of 1-benzyl-3-aminopyrrolidine that is used in the method. | 10-16-2008 |
| 20080255372 | Process for Preparing Glyceryl Carbonate - The present invention relates to a process for preparing highly pure glyceryl carbonate by transesterifying dialkyl carbonates or cyclic carbonates in the presence of a basic catalyst. | 10-16-2008 |
| 20080255373 | PROCESS FOR THE PRODUCTION OF GLYCEROL CARBONATE ESTERS - The invention relates to a process for the production of glycerol carbonate esters corresponding to formula (I): | 10-16-2008 |
| 20080255374 | PROCESS FOR CHARGING A LONGITUDINAL SECTION OF A CATALYST TUBE - A process for charging a longitudinal section of a catalyst tube with a homogeneous fixed catalyst bed section whose active composition is at least one multielement oxide or comprises elemental silver on an oxidic support body and whose geometric shaped catalyst bodies and shaped inert bodies have a specific inhomogeneity of their longest dimensions. | 10-16-2008 |
| 20080255375 | Alkenylsuccinic Anhydrides Formed From Oligomers Of C4-To C8-Olefins And Maleic Anhydride, Processes For Their Preparation And Their Use - Alkenylsuccinic anhydrides obtainable by reaction of maleic anhydride with mixtures of oligomers having at least 12 carbon atoms which are obtainable by oligomerization of a hydrocarbon mixture which comprises at least two olefins having 4 to 8 carbon atoms over a catalyst which comprises a transition metal, processes for the preparation of the alkenylsuccinic anhydrides and their use as sizes in the production of paper, board and cardboard. | 10-16-2008 |
| 20080255376 | Method For the Production of Dioxolane - Processes comprising: providing a reactive distillation column having an upper region, a middle region and a lower region; feeding ethylene glycol and an aqueous formaldehyde solution into the reactive distillation column in the middle region of the reactive distillation column; reacting the ethylene glycol and the aqueous formaldehyde solution in the reactive distillation column in the presence of a catalyst to form dioxolane; removing a product stream comprising dioxolane in an amount of at least 75% by weight from the upper region of the reactive distillation column; and removing a bottom stream comprising one or more components having boiling points higher than dioxolane from the lower region of the reactive distillation column. | 10-16-2008 |
| 20080255377 | Processes for the Manufacture of Chiral and Racemic Forms of 3-Aminotetrahydrofurans, Their Salts and Derivatives - A novel process for the synthesis of (S)-3-Amino-tetrahydrofuran and (R)-3-Amino-tetrahydrofuran is described. The process is applicable for substituted chiral-3-aminotetrahydrofuran derivatives. | 10-16-2008 |
| 20080255378 | High productivity process for non-phenolic ethoxylates - The present invention provides a process for the production of an ethoxylate involving charging a portion of product from a previous preparation (a “heel”) or an ethoxylate to a reactor, optionally, charging from about 0.2 wt. % to an amount equal or greater than the amount of heel of a C | 10-16-2008 |
| 20080255379 | Direct epoxidation process using a mixed catalyst system - The invention is a process for epoxidizing an olefin with hydrogen and oxygen in the presence of a catalyst mixture containing a titanium or vanadium zeolite and a supported catalyst comprising palladium, gold, and an inorganic oxide carrier. Prior to its use in the epoxidation process, the supported catalyst is calcined in the presence of oxygen at a temperature from 450 to 800° C. and reduced in the presence of hydrogen at a temperature greater than 20° C. The process results in significantly reduced alkane byproduct formed by the hydrogenation of olefin. | 10-16-2008 |
| 20080255380 | Process and Intermediates for the Preparation of Sulfonyl Derivatives of Cholecalciferol - Preparation of sulfonyl derivatives of cholecalciferol of Formula 1, wherein R | 10-16-2008 |
| 20080255381 | BISBIPHENYLACYLPHOSPHINE OXIDE AND PREPARATION METHOD THEREFORE - A bisbiphenylacylphosphine oxide of formula (I) and its preparation method are provided. The formula of —Ar— is | 10-16-2008 |
| 20080255382 | Novel Sirtuin Activating Compounds and Methods for Making the Same - The present invention includes methods for preparing resveratrol, resveratrol esters and substituted and unsubstituted stilbenes of the formula given below; where each Y is —O or halogen, each Z is —O or halogen, each n and each m is independently the value of 0, 1, 2, 3, 4 or 5, each A and each B is independently selected from P | 10-16-2008 |
| 20080255383 | PREPARATION OF RIVASTIGMINE AND ITS SALTS - There are provided processes for making rivastigmine. In one embodiment, the process includes reacting S-(−)-[1-(3-hydroxyphenyl)ethyl]dimethylamine with N-ethyl-N-methyl carbamoyl chloride in the presence of an organic base to obtain a free base of rivastigmine. | 10-16-2008 |
| 20080255384 | THREE CARBON PRECURSOR SYNTHONS | 10-16-2008 |
| 20080255385 | METHOD FOR PRODUCING OPTICALLY ACTIVE (4E)-5-CHLORO-2-ISOPROPYL-4-PENTENOIC ACID OR BASIC AMINO ACID SALT THEREOF - To provide a method for producing an optically active (4E)-5-chloro-2-isopropyl-4-pentenoic acid, a basic amino acid salt thereof or an optically active (4E)-5-chloro-2-isopropyl-4-pentenoic acid ester with high yield and high optical purity by simple operation. | 10-16-2008 |
| 20080255386 | PROCESS FOR PREPARING IBANDRONATE - The invention relates to a novel multi step synthesis of 3-(N-methyl-N-pentyl)amino-1-hydroxypropane-1,1-diphosphonic acid, monosodium salt, monohydrate, of the formula | 10-16-2008 |
| 20080255387 | TRIARYLAMINE DERIVATIVE - A triarylamine derivative is represented by the following Formula (I). In Formula (I): R | 10-16-2008 |
| 20080255388 | TRIARYLAMINE DERIVATIVE - A triarylamine derivative is represented by the following Foimula (I). In Formula (I): R | 10-16-2008 |
| 20080255389 | COST EFFECTIVE METHOD FOR SYNTHESIS OF TRIARYLAMINE COMPOUNDS - A process for forming a triarylamine compound includes reacting a halogenated aryl alcohol with an alcohol protecting agent and a first base to form a halogenated protected aryl alcohol compound, and reacting the halogenated protected aryl alcohol compound with an amine in the presence of a suitable catalyst and a second base. | 10-16-2008 |
| 20080255390 | Shaped Body Comprising an Aluminosilicate and Aluminium Oxide and Process for the Continuous Preparation of Methylamines - Shaped body comprising an aluminosilicate and aluminum oxide, wherein the shaped body has a molar Al/Si ratio in the range from 10 to 30 and an at least bimodal pore distribution for pores having a diameter of greater than 1 nm, with the volume of the pores of the shaped body having a diameter of greater than 10 nm corresponding to at least 40% of the total pore volume of the shaped body,
| 10-16-2008 |
| 20080255391 | Chiral Phosphorus Compounds - A process for the stereoselective preparation of a P-chiral four-co-ordinated phosphorus compound, the process comprising reacting a first reactant selected from the group consisting of a chiral alcohol, chiral amine or chiral thiol, with a second reactant comprising a P-chiral three-co-ordinated phosphorus compound, in the presence of an electrophile. | 10-16-2008 |
| 20080255392 | PROCESS FOR PRODUCING CYCLOALKANOL AND/OR CYCLOALKANONE - There is provided a process with which the cycloalkane is oxidized so as to produce a cycloalkanol and/or a cycloalkanone with an improved conversion of the cycloalkane. | 10-16-2008 |
| 20080255393 | Method for Purifying and Concentrating Dinitrogen Monoxide - The present invention relates to a process for purifying a gas mixture comprising dinitrogen monoxide and to the use of a gas mixture purified in this way as an oxidant for olefins. In a further embodiment, the present invention also relates to a process for preparing ketones comprising the oxidation of an olefin with a gas mixture which has been purified in accordance with the invention and comprises dinitrogen monoxide. | 10-16-2008 |
| 20080255394 | High productivity process for alkylphenol ethoxylates - The present invention provides a process for the production of an alkylphenol ethoxylate involving charging a portion of product from a previous preparation (a “heel”) or an ethoxylate to a reactor, optionally, charging from about 0.2 wt. % to an amount equal to or greater than the weight of the heel of an alkylphenol starter to the reactor, charging ethylene oxide to activate a double metal cyanide (“DMC”) catalyst, adding the alkylphenol starter simultaneously with ethylene oxide for a portion of the process and continuing ethylene oxide addition following completion of the simultaneous alkylphenol starter and ethylene oxide addition. The process of the present invention provides significant improvements in cycle time and safety in producing ethoxylates which may find use in or as surfactants. | 10-16-2008 |
| 20080255395 | Process for producing bis-alkoxylated diols of bisphenol a from spent polycarbonate discs(PC) or PC waste - This invention provides one-pot reaction for digesting polycarbonate waste with alkylene glycol in the presence of a basic catalyst at 180° C. under normal atmospheric pressure. The digested product mixture was found to consist of bisphenol A (BPA) and monoalkoxylated and bisalkoxylated diols of BPA. Alkoxylation of BPA and monoalkoxylated diols of BPA is performed by adding urea or urea derivative (or carbonic acid ester or amine ester) to the digested product mixture at a high temperature under normal atmospheric pressure to obtain the final product, i.e., bisalkoxylated diols of BPA in high yield. The bisalkoxylated diols of BPA may be used as raw materials to synthesize polymer such as polyurethane (PU) or polyester. | 10-16-2008 |
| 20080255396 | PROCESS FOR THE REDUCTION OF ACIDIC CONTAMINATES IN FLUORINATED HYDROCARBONS - The present invention relates to processes for reducing the concentration of acidic impurities HF, HCl, HBr, HI, HNO | 10-16-2008 |
| 20080255397 | Promotors for Controlling Acidity and Pore Size of Zeolite Catalysts for Use in Alkylation - A metal-modified alkylation catalyst including a metal/zeolite is provided where the metal is one or two selected from the group consisting of yttrium and a rare earth of the lanthanide series other than cerium. Where two metals are used, one may be Ce or La. The metal-promoted zeolite is useful as a molecular sieve aromatic alkylation catalyst for the production of ethylbenzene by the ethylation of benzene in the liquid phase or critical phase. An alkylation product is produced containing ethylbenzene as a primary product with the attendant production of heavier alkylated by-products of no more than 10-60 wt % of the ethyl benzene. | 10-16-2008 |
| 20080255398 | Aromatization of alkanes using a germanium-zeolite catalyst - This invention relates to a process for the aromatization of C | 10-16-2008 |
| 20080255399 | Method for Production of Diphenylethylene - The invention relates to a method for production of diphenylethylene (DPE) comprising the steps of: (a) catalytic dehydrogenation of diphenylethane (DPA) in the presence of water, (b) addition of a light organic solvent to the mixture from step (a) and (c) decanting the mixture from step (b) with recovery of a flow comprising diphenylethylene as a mixture with the solvent added in step (b). The invention further relates to a given mixture of DPE, DPA and solvent and use thereof in polymerisation. | 10-16-2008 |
| 20080255400 | Hydrotalcite-Like Substance, Process for Producing the Same and Method of Immobilizing Hazardous Substance - A hydrotalcite-like substance that is capable of ion exchange with target anions, being of small crystal size and that exhibits large basal spacing, excelling in anion exchange performance; a process for producing the same; and a method of immobilizing hazardous substances. A hydrotalcite-like substance is produced by mixing an acidic solution containing aluminum ions and magnesium ions with an alkaline solution containing an alkali to thereby synthesize a hydrotalcite-like substance, followed by, without ageing, water removal or neutralization. The molar ratio of aluminum ions and magnesium ions is preferably in the range of 1:5 to 1:2. Hazardous substances can be immobilized by pulverizing the hydrotalcite-like substance after synthesis and adding the powder to a subject, or adding a hydrotalcite-like substance in slurry form to a subject, or carrying out addition so as to cause the synthesis directly at the position of the subject. Furthermore, anion adsorption can be performed by a filter containing the hydrotalcite-like substance. | 10-16-2008 |
| 20080255401 | Processing Apparatus, Processing Method and Method of Processing Innoxious Object - [OBJECT] To efficiently and assuredly making an object to be treated containing an agricultural chemical innoxious. | 10-16-2008 |
| 20080255402 | SYSTEM FOR SEPARATING AND EXTRACTING HEAVY METALS FROM POLLUTED LIQUID WASTE - A system for separating and extracting heavy metals from polluted liquid waste includes a pressurizing unit for pressurizing an extracting solvent using a high-pressure gas, so that the extracting solvent contains supersaturated air and is then jetted into a pneumatic stirring, reacting and separating apparatus, in which the supersaturated air in the extracting solvent instantaneously leaches out to thereby produce a large quantity of micro-sized extracting solvent-bearing bubbles that react with heavy metal-polluted liquid waste contained in the pneumatic stirring, reacting and separating apparatus to separate heavy metals from water. A gas supplying device is connected to and supplies gas to the pneumatic stirring, reacting and separating apparatus to stir the heavy metal-polluted liquid waste. And, a pumping unit is connected to the pneumatic stirring, reacting and separating apparatus to pump out heavy metal-separated water to achieve the object of removing heavy metals from liquid waste. | 10-16-2008 |
| 20080255403 | MAGNETIC NANOPARTICLE THERAPIES - Various compositions, methods, and devices are provided that use fluorescent nanoparticles, which can function as markers, indicators, and light sources. The fluorescent nanoparticles can be formed from a fluorophore core surrounded by a biocompatible shell, such as a silica shell. In one embodiment, the fluorescent nanoparticles can be delivered to tissue to mark the tissue, enable identification and location of the tissue, and/or illuminate an area surrounding the tissue. In another embodiment, the fluorescent nanoparticles can be used on a device or implant to locate the device or implant in the body, indicate an orientation of the device or implant, and/or illuminate an area surrounding the device or implant. The fluorescent nanoparticles can also be used to provide a therapeutic effect. | 10-16-2008 |
| 20080255404 | MEDICAL DEVICE AND USING METHOD THEREOF - Disclosed herein is a medical device including: a positioning catheter to be inserted into a blood vessel in the vicinity of an affected region; a treatment catheter to be inserted to reach the affected region; and attracting means provided at respective predetermined positions of both the catheters to apply a magnetic force in a direction of attracting each other; wherein the magnetic force of the attracting means restricts floating of the treatment catheter. | 10-16-2008 |
| 20080255405 | Fluid Pressure Generating Means - A fluid pressure generating means ( | 10-16-2008 |
| 20080255406 | Implantable Auditory Stimulation Systems Having a Transducer and a Transduction Medium - Systems and methods for improving sound perception in a subject equipped with an implantable vibratory unit comprising a transducer and a transduction medium in which the transducer is disposed within or against the transduction medium. The transducer is configured to impart vibrations to a vibratory structure of a subject's ear through the transduction medium in response to an electrical signal corresponding to sound. In certain embodiments, the transduction medium directly contacts the vibratory structure of the subject's ear, whereas the transducer does not. | 10-16-2008 |
| 20080255407 | Bi-directional system for dissecting and harvesting vessels - A method and apparatus for bi-directionally dissecting and harvesting a vessel includes a dissector device that is at least temporarily secured to a harvester device. | 10-16-2008 |
| 20080255408 | SYSTEMS AND METHODS OF PROMOTING ENDOTHELIALIZATION OF A HYBRID LOWER LIMB ARTERY BYPASS VASCULAR GRAFT IN A MAMMAL - Hybrid synthetic grafts and embodiments of systems and methods for producing hybrid vascular grafts that can yield implantable grafts that combine synthetic grafts with living cells. Embodiments of systems can include a pressure/flow loop subsystem having an external flow loop system coupled to a specimen holder, where the pressure/flow loop subsystem is capable of adjusting at least two dynamic conditions in the specimen holder or a diameter of a specimen in the specimen holder. Embodiments of methods can promote endothelialization of a hybrid lower limb artery bypass vascular graft by placing the hybrid lower limb artery bypass vascular graft in a system embodiment according to the invention under conditions effective to promote stem cells to form a confluent monolayer on the hybrid vascular graft. | 10-16-2008 |
| 20080255409 | PROCESS TO IMPROVE THE PROFITABILITY OF TESTS OR TREATMENTS WITH ENDOSCOPY CAPSULES - In a method for improving profitability of a medical procedure supervised through a medical facility, the medical procedure including ingestion of an endoscopy capsule by a patient of the medical facility, the endoscopy capsule is retrieved after being naturally voided by the patient after the endoscopy capsule traverses the gastrointestinal tract of the patient, and a reward is paid to a person who returns the retrieved endoscopy capsule to a location associated with the medical facility. An endoscopy capsule usable with this procedure has a capsule body containing medical data-gathering components, and an exchangeable cover that covers the capsule body that is formed of a material allowing removal of the cover after the capsule has passed through the gastrointestinal tract of the patient, so that a new cover can be provided on the capsule body. | 10-16-2008 |
| 20080255410 | CAPSULE ENDOSCOPE AND MANUFACTURING METHOD THEREOF - A fitting section at which a cylindrical cover is fitted into a transparent cover, the cylindrical cover containing therein a CCD imager, and the transparent cover making visible light from a subject incident on the CCD imager, and being formed of a member transmitting laser light, is irradiated with laser light from the outside of an endoscope casing, thereby welding the cylindrical cover and the transparent cover together. | 10-16-2008 |
| 20080255411 | TOOL FOR ENDOSCOPE AND ENDOSCOPE SYSTEM - An endoscope system includes a light source, a scope, a detector, an adjuster, and a tool. The light source emits illuminating light to illuminate a subject. The scope transmits the illuminating light for emission from the end of the scope. The detector detects the luminance and/or chromaticity of an entering light that enters the scope. The adjuster adjusts the light amount and/or white balance of the illuminating light, based on the luminance and/or chromaticity of the entering light. The end of the scope is inserted into the tool. The tool includes a reflecting member that reflects the illuminating light emitted from the end of the scope so as to become the entering light. The distance between the end of the scope that is inserted into the tool and the reflecting member is adjustable. | 10-16-2008 |
| 20080255412 | ENDOSCOPIC BARREL WITH CONNECTOR - An endoscopic assembly for an endoscope is disclosed. The assembly comprises a ligator barrel having proximal and distal portions. The proximal portion has a seat and a receiving wall extending to a proximal end. The receiving wall has a first threaded portion formed thereon. The assembly further comprises a connector for connecting the ligator barrel about the endoscope. The connector has a scope portion and a tip portion. The scope portion has a receiving end through which the endoscope is disposed to engage the seat for connecting the ligator barrel about the endoscope. The tip portion has a second threaded portion formed thereon and are configured to cooperate with the first threaded portion to receive the receiving wall and attach the connector with the ligator barrel. The first and second threaded portions are configured to cooperate with each other to tighten the connection of the ligator barrel about the endoscope as the threads increase surface area contact therebetween. | 10-16-2008 |
| 20080255413 | Powered surgical instrument - A surgical instrument including a housing, an endoscopic portion, a shaft portion and an end effector is disclosed. The endoscopic portion extends distally from the housing and defines a longitudinal axis. The shaft portion is selectively connectable to a distal end of the endoscopic portion. The end effector is selectively connectable to a distal end of the shaft portion. | 10-16-2008 |
| 20080255414 | FLUORESCENT NANOPARTICLE SCOPE - Various compositions, methods, and devices are provided that use fluorescent nanoparticles to function as markers, indicators, and light sources. In one embodiment, an endoscopic adaptor is provided for viewing fluorescent nanoparticles. The adaptor can be configured to removably mate to a portion of an endoscope, such as an eyepiece, and it can be adapted to contain a filter for filtering light received through the viewing lumen of the eyepiece. In an exemplary embodiment, the filter is configured to transmit fluorescent light while blocking visible light, to thereby enable a structure containing one or more fluorescent nanoparticles to be viewed through the endoscope. | 10-16-2008 |
| 20080255415 | ENDOSCOPE PROCESSOR - An endoscope processor comprising a touch-panel input unit, a mechanical switch unit, and a controller, is provided. The endoscope processor controls an endoscope system. The touch-panel input unit comprises a touch-panel monitor. A command to carry out a function of the endoscope system is input via a command-input display displayed on the touch-panel monitor. The mechanical switch unit is manipulated to carry out at least one function among a light-switching function, a pump-switching function, and a white-balance-start switching function. The controller carries out a function corresponding to the command input via the touch-panel input unit or the mechanical switch unit. | 10-16-2008 |
| 20080255416 | Endoscope with Miniature Imaging Arrangement - A miniature endoscope with an imaging arrangement associated with its distal tip portion includes an image sensor chip with a two-dimensional array of light-sensitive pixels and a lens arrangement deployed for focusing light from a field of view onto the image sensor chip so as to generate an image of a scene viewed from the distal tip portion. The lens arrangement is preferably directly affixed to the image sensor chip by a quantity of transparent adhesive. Use of bidirectional communication along data lines to the image sensor chip allows use of only four wires connecting to the chip. These and other features allow miniaturization of the endoscope to a diameter of about 2 millimeters while still generating color images of high dynamic range. | 10-16-2008 |
| 20080255417 | METHOD FOR REDUCING THE FRICTION OF A MEDICO-TECHNICAL RUBBER TUBE - There are described a method for reducing the friction of a medico-technical rubber tube, according to which first a tube is produced of rubber and is then after-treated by annealing and/or washing, as well as an endoscope. | 10-16-2008 |
| 20080255418 | Powered surgical instrument - A surgical instrument including a housing, an endoscopic portion, a drive gear, a drive motor, a shift motor and an end effector is disclosed. The endoscopic portion extends distally from the housing and defines a longitudinal axis. The drive gear is disposed at least partially within the housing and is rotatable about a drive gear axis which extends therethrough. The drive gear is selectively movable along the drive gear axis. The drive motor is disposed in mechanical cooperation with the drive gear and is configured to rotate the drive gear. The shift motor is disposed in mechanical cooperation with the drive gear and is configured to move the drive gear along the drive gear axis. The end effector is disposed adjacent a distal portion of the endoscopic portion. | 10-16-2008 |
| 20080255419 | METHODS AND DEVICES FOR REDUCING REFLECTION-ILLUMINATED ARTIFACTS - The present disclosure is generally directed towards methods and devices for reducing or eliminating reflection-illuminated artifacts. The methods and devices in several embodiments can include providing a transparent lens cover with a blocking member for reflecting or absorbing internally-reflected light. The lens cover can be attached at the distal end of an endoscope, cannula, and/or lumen in some embodiments. Alternatively, the lens cover can be a permanent part of the endoscope, lumen, and/or cannula. | 10-16-2008 |
| 20080255420 | Surgical instrument - A surgical instrument having an instrument shaft having proximal and distal ends, a tool disposed from the distal end of the instrument shaft, a control handle coupled from the proximal end of the instrument shaft, a distal motion member for coupling the distal end of the instrument shaft to the tool, a proximal motion member for coupling the proximal end of the instrument shaft to the handle and actuation means extending between distal and proximal motion members for coupling motion of the proximal motion member to the distal motion member for controlling the positioning of the tool. Rotation control and locking members are also disclosed. | 10-16-2008 |
| 20080255421 | Articulating tool with improved tension member system - The invention provides surgical or diagnostic tools and associated methods that offer improved user control for operating remotely within regions of the body, and improved methods of assembling the tools. In some embodiments these tools include a proximally-located actuator for the operation of a distal end effector, as well as proximally-located actuators for articulational and rotational movements of the end effector. Control mechanisms and methods refine operator control of end effector actuation and of these articulational and rotational movements. The articulation mechanisms comprise pairs of links, one link distal and the other proximal, configured such that movement of a proximal link is transferred to the distal link by way of tension bearing members. Embodiments of the invention include a guide for such tension bearing members that facilitates assembly of the tool. Embodiments also include improved methods for attaching tension bearing members to the links. The inventions disclosed herein may also be used with articulating devices outside of the surgical and diagnostic fields. | 10-16-2008 |
| 20080255422 | MEDICAL DEVICE - A medical instrument which is inserted into a body cavity includes: an insertion part which has a bending part capable of bending in a predetermined range; a plurality of joint rings which are provided in the bending part and are connected to each other in the axial direction of the insertion part; a manipulating part which manipulates the bending part; and a wire which is inserted into the plurality of the joint rings and connects the bending part with the manipulating part, wherein: the plurality of the joint rings comprises a connecting part, a portion of which is provided so as to protrude from the outer peripheral surface and which is connected to the joint ring of the distal side in the axial direction of the insertion part and a connected part which is connected to the joint ring of the proximal side in the axial direction of the insertion part; the connecting part has a linear cross section orthogonal to the axis of the joint ring, and a curved base portion which is a portion of the connecting part protruding from the outer peripheral surface of the joint ring and has no corner; and end portions of the connecting part in the circumferential direction are formed so as to contact with the base portion at the end surface of the distal side of the joint ring. | 10-16-2008 |
| 20080255423 | MEDICAL DEVICE - A medical instrument for performing a medical procedure within a body cavity includes: an insertion part which is inserted into the body cavity and has a bending part capable of bending in a predetermined range; a manipulating part which manipulates the bending part; a wire which connects the bending part with the manipulating part; and a clutch which is provided in the manipulating part and maintains a bending state of the bending part. | 10-16-2008 |
| 20080255424 | Endoscopes including distal chamber and related methods of use - Embodiments of the invention include an endoscope including a distal chamber and related methods of use, for example, with an endoscopic instrument. | 10-16-2008 |
| 20080255425 | NANOPARTICLE TREATED MEDICAL DEVICES - Various compositions, methods, and devices are provided that use fluorescent nanoparticles, which can function as markers, indicators, and light sources. The fluorescent nanoparticles can be formed from a fluorophore core surrounded by a biocompatible shell, such as a silica shell. In one embodiment, the fluorescent nanoparticles can be delivered to tissue to mark the tissue, enable identification and location of the tissue, and/or illuminate an area surrounding the tissue. In another embodiment, the fluorescent nanoparticles can be used on a device or implant to locate the device or implant in the body, indicate an orientation of the device or implant, and/or illuminate an area surrounding the device or implant. The fluorescent nanoparticles can also be used to provide a therapeutic effect. | 10-16-2008 |
| 20080255426 | AUTOFLUORESCENCE ENDOSCOPE SYSTEM AND LIGHT-SOURCE UNIT - An autofluorescence endoscope system including first and second exciting light sources, an exciting-light cut-off filter, an imaging device, a light-source controller, and an imaging device driver, is provided. The first and second exciting light sources emit first and second exciting light, respectively. The wavelengths of the first and second exciting lights range in a first and second band, respectively. The first and second exciting lights make an organ autofluoresce. The wavelength in the second band is longer than that of the first band. The exciting-light cut-off filter attenuates a light component at least of the first or second band from an optical image. The imaging device captures an optical image of the subject passing the exciting-light cut-off filter. The light-source controller controls the first and second exciting light sources. | 10-16-2008 |
| 20080255427 | LIGATION APPARATUS AND A LIGATION MEMBER - Provided is a grasper including an introduction tube that is capable of being inserted into a body cavity; an operational elongate body that is inserted into the introduction tube so as to advance and retract; and a clip that is attached to a distal end portion of the introduction tube and is operated by the relative movement between the operational elongate body and the introduction tube so as to grasp a body tissue, then is indwelled in a body. The clip has a plurality of grasping arms which are operated to be moved by the operational elongate body or the introduction tube, at least in a direction where the grasping arms are closed, so as to grasp the body tissue; and a retracting portion which retracts a portion of the body tissue between the plurality of grasping arms. | 10-16-2008 |
| 20080255428 | Systems and Methods for Active Listening/Observing and Event Detection - Embodiments of the present invention provide a method of monitoring an environment comprising: monitoring at least one data stream wherein the data stream is a data stream in the environment; detecting a specified event from the data stream; and triggering a response to the specified event. Embodiments of the present invention provide a system for monitoring an environment comprising: a receiver adapted to receive at least one input data stream wherein the input data stream is a data stream in the environment; an active listener/observer system adapted to monitor the data stream; and an interface adapted to express at least one output stream. Embodiments of the present invention provide a computer-readable medium having instructions comprising: an active listener/observer routine configured to monitor at least one data stream; a detection routine configured to find specified events in the data stream; and an output routine configured to express a response event. | 10-16-2008 |
| 20080255429 | SIMULATED SECONDARY GAIN MODEL WITH CONTINUOUS FEEDBACK TO DIAGNOSTIC TESTING PARAMETERS AND INTERPRETATION IN A MEDICAL LEGAL SETTING - The invention generally relates to compositions and methods for the use of a simulated secondary gain model for use in medical legal setting where there is dispute about the validity of a medical patient's injuries. This model is used to ascertain the false positive rate of a given diagnostic test or suite of same and is then used to reevaluate the test on an ongoing basis after changes have been made to reduce the false positive rate. | 10-16-2008 |
| 20080255430 | PORTABLE DEVICE WITH BIOMETRIC SENSOR ARRANGEMENT - The present invention is directed to a biometric sensor system | 10-16-2008 |
| 20080255431 | Early Detection and Warning of Harmful Agents - A method of detecting the presence of harmful agents in the environment is disclosed. The method comprises: providing a plurality of portable agent detectors, placing the detectors on vectors in the environment, connecting the detectors over a communication network, and, upon detection of an agent by a first detector, signaling detectors identified as being nearby to carry out corresponding agent detection tests, thereby to confirm or localize an initial agent detection. | 10-16-2008 |
| 20080255432 | Patient Monitor with User-Defined Monitored Parameters - In a medical monitoring system ( | 10-16-2008 |
| 20080255433 | OPTOACOUSTIC MONITORING OF MULTIPLE PARAMETERS - An optoacoustic technique for absolute, accurate, continuous, and real-time measurement of a variety of important diagnostic variables is disclosed, where the variables include: (1) noninvasive measurements of circulating blood volume (BV) and cardiac output (CO); (2) calculation from the measured variables of cardiac index (CI) and systemic oxygen delivery (DO | 10-16-2008 |
| 20080255434 | METHOD AND APPARATUS FOR PROVIDING DATA PROCESSING AND CONTROL IN MEDICAL COMMUNICATION SYSTEM - Methods and apparatus for providing data processing and control for use in a medical communication system are provided. | 10-16-2008 |
| 20080255435 | LOW NOISE OXIMETRY CABLE INCLUDING CONDUCTIVE CORDS - In an embodiment, one or more conductive cable cords are twisted with the sensitive signal carrying cables. The cords may advantageously comprise dummy wires, or very flexible hollow cables without an inner conductor. As the conductive cords do not carry and inner conductor, the conductive cords are individually flexible and small, resulting in a twisted bundle that more is flexible while potentially having a smaller outer diameter. | 10-16-2008 |
| 20080255436 | Method for Enhancing Pulse Oximery Calculations in the Presence of Correlated Artifacts - A method for determining a physiological parameter in the presence of correlated artifact, including obtaining two digital waveforms, x and y, the waveforms being representative of the absorption of two wavelengths of electromagnetic energy received from a blood-perfused tissue, and where each of the waveforms has a component corresponding to a plethysmographic waveform and a component corresponding to the correlated artifact; calculating several weighted difference waveforms of the form x−R*y, where R is a multiplier, by varying R over a range; evaluating the several weighted difference waveforms using a shape characteristic of the weighted difference waveform; identifying a weighted difference waveform most closely representative of and one most different from the plethysmographic waveform; determining a pleth-based physiological parameter using the waveform most closely representative of the plethysmographic waveform; determining at least one artifact-based physiological parameter using the waveform most different from the plethysmographic waveform; and rejecting other possible candidate values for the pleth-based physiological parameter using the artifact-based physiological parameter. | 10-16-2008 |
| 20080255437 | METHOD AND APPARATUS FOR PROVIDING DATA PROCESSING AND CONTROL IN MEDICAL COMMUNICATION SYSTEM - Methods and apparatus for providing data processing and control for use in a medical communication system are provided. | 10-16-2008 |
