41st week of 2011 patent applcation highlights part 36 |
Patent application number | Title | Published |
20110250626 | Visual Assays for Coatings Incorporating Bioactive Enzymes for Catalytic Functions - Disclosed herein are materials such as a coating, comprising a lipolytic enzyme or organophosphrous compound degrading enzyme. Also disclosed herein are methods of visually detecting enzyme activity in a coating by contacting the coating with a substrate of an enzyme and a visual indicator that changes appearance upon production of a product of enzyme activity on a tack-free coating surface. | 2011-10-13 |
20110250627 | METHODS FOR ASSAYING PERCENTAGE OF GLYCATED HEMOGLOBIN - The invention provides enzymatic methods for direct determination of percentage of glycated hemoglobin in blood samples without the need of a separated measurement of total hemoglobin content in blood samples. The methods utilizes one or two different types of oxidizing agents which selectively oxidize low-molecular weight reducing substances and high-molecular weight (mainly hemoglobin) reducing substances in blood samples, coupled with enzymatic reactions catalyzed by proteases, fructosyl amino acid oxidase. The amount of hydrogen peroxide generated in the reaction is measured for determination of percentage of glycated hemoglobin in blood samples. The invention provides kits for performing the methods of the invention. | 2011-10-13 |
20110250628 | Hcv replicons containing ns5b from genotype 2b - The present invention features methods for enhancing the ability of a genotype 2b NS5B sequence to function in a replicon, for producing replicons containing a functional genotype 2b NS5B, and for using replicons to measure the ability of a compound to affect HCV replication that is sustained with the genotype 2b polymerase. Also featured is a genotype 1b NS4B adaptive mutation. The ability to produce replicons containing a functional genotype 2b NS5B is illustrated by the production of chimeric replicons based on HCV genotype 1b where substantially all the NS5B sequence is replaced with a genotype 2b NS5B. | 2011-10-13 |
20110250629 | ALCOHOL PRODUCTION PROCESS - The invention relates to the microbial fermentation of gaseous substrates, particularly to methods of mitigating and/or reducing alcohol toxicity effects on a microbial culture at elevated alcohol concentrations during fermentation. The invention relates particularly to microbial fermentation of substrates comprising CO and the effects of alcohol toxicity are reduced or mitigated by maintaining the temperature below the optimum operating temperature by cooling the fermentation broth. | 2011-10-13 |
20110250630 | Motif-grafted hybrid polypeptides and uses thereof - Provided herein are hybrid polypeptides that specifically bind to a disease-associated isoform of a polypeptide involved in diseases of protein aggregation. The hybrid polypeptides can be used for diagnosis and treatment of such diseases. In a particular embodiment, a hybrid protein that specifically binds to the infectious form of a prion (PrP | 2011-10-13 |
20110250631 | PROTEOGLYCAN DEGRADING MUTANTS FOR TREATMENT OF CNS - The present disclosure relates to the preparation and deletion mutants of chondroitinase proteins and their use in methods for promoting the diffusion of therapeutic composition into tissues and their use for neurological functional recovery after central nervous system (“CNS”) injury or disease. | 2011-10-13 |
20110250632 | METHODS FOR CONDUCTING CELLULAR ASSAYS - The present invention relates to cryopreserved cell cultures, methods for cryopreserving cells and methods for conducting cellular assays on such cells. A cryopreserved cell culture of the invention comprises a container having at least a surface which is coated with poly-lysine and frozen cells supported on the surface. | 2011-10-13 |
20110250633 | Device and Method for Automatically Analyzing Micro Organisms in a Sample - Device for automatically analyzing micro organisms in an aqueous sample using filter cytometry comprising at least one filter holder and processing modules, wherein the filter holder is arranged to contain a filter for receiving the sample, wherein the processing modules comprise sample application means for applying the sample to the filter in the holder and imaging means for imaging the micro organisms on the filter, wherein the device furthermore comprises displacement means for automatically moving the filter holder between the processing modules and wherein each of the modules and the filter holder are arranged to removable connect for interaction. | 2011-10-13 |
20110250634 | Tissue Container for Molecular and Histology Diagnostics Incorporating a Breakable Membrane - A container for storing a biological sample for molecular diagnostic testing and/or histological testing is provided. The container includes a first chamber for receiving a sample holder therein, a second chamber, and a closure for enclosing the container. A breakable membrane, such as a piercable foil, extends within the container and separates the two chambers. When the breakable membrane is broken, fluid can pass between the first and second chambers. The membrane may be broken through an activator on the closure, such as a depressible member or a rotatable carrier, causing the sample holder to break through the membrane. | 2011-10-13 |
20110250635 | Method and System for Processing Biomass - A method and system for processing biomass. The method uses an apparatus with a housing, a rotor inside of the housing, and a plurality of protrusions extending from the rotor. The method includes placing the biomass in a fluid medium, inducing cavitation within the fluid to partially separate the biomass, sending the biomass and fluid into the housing, rotating the rotor to further separate the biomass, heating the biomass and fluid, and maintaining the acidity of the fluid and biomass at a pH of between approximately 2 to 6. The system includes apparatus each having a housing and a rotor within the housing. One apparatus has abutting, alternating height protrusions extending from the rotor. Another apparatus has grooves formed in the rotor and an end wall of the housing. Another apparatus has two rows of protrusions extending from the rotor that are spaced apart no less than approximately 6 millimeters. | 2011-10-13 |
20110250636 | Novel gene GMS 01 - The present invention relates to microorganisms genetically engineered to increase yield and/or efficiency of biomass production from a carbon source, such as e.g. glucose. Processes for generating such microorganisms are also provided by the present invention. The invention also relates to polynucleotide sequences comprising genes that encode proteins that are involved in the bioconversion of a carbon source such as e.g. glucose into biomass. The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. Also included are processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms leading to a microorganism with reduced carbon source diversion, i.e. higher yield and/or efficiency of biomass production from a carbon source such as e.g. glucose. | 2011-10-13 |
20110250637 | METHOD FOR PRODUCING SUGAR LIQUID - A sugar liquid containing only very small amounts of fermentation-inhibiting substances is produced by a method for producing a sugar liquid using a cellulose-containing biomass as a raw material, the method including: (1) a step of hydrolyzing a cellulose-containing biomass to produce an aqueous sugar solution; and (2) a step of filtering the obtained aqueous sugar solution through a nanofiltration membrane and/or reverse osmosis membrane to collect a purified sugar liquid from the feed side, while removing fermentation-inhibiting substances from the permeate side. | 2011-10-13 |
20110250638 | LIGNOCELLULOSIC BIOMASS CONVERSION - The present invention relates to a process for the production of second generation biofuels and/or sugar based chemicals—for example ethanol, butanol etc—and/or materials—for example plastics, single cell proteins etc.—together with sulfonated lignin from lignocellulosic biomass, in particular from lignocellulosic biomass comprising, among others, annual plants, agricultural waste, or wood. In particular, the present invention relates to a process for the production of sugar based chemicals, biofuels or materials together with sulfonated lignin from lignocellulosic biomass comprising the pretreatment of a lignocellulosic biomass in a sulfite cooking step. | 2011-10-13 |
20110250639 | METHODS FOR PRODUCING SOLUBLE MEMBRANE-SPANNING PROTEINS - Methods for producing membrane-spanning polypeptides in high yields, with native conformation, and/or in soluble form include solubilizing in non-ionic or zwitterionic detergents, as well as use of promoters and expression vectors for expressing high yields of membrane-spanning polypeptides in bacterial cells. Mutated promoters provide tight control of membrane-spanning polypeptides in bacterial cell hosts. | 2011-10-13 |
20110250640 | METHOD OF RECLONING PRODUCTION CELLS - A new method for selecting clones and recloning mammalian cells which are of importance for the production of biopharmaceuticals, preferably hamster or mouse myeloma cells, with a high degree of automation and throughput. The invention relates to methods of depositing and replicating single cell clones of the cells in question. The invention also relates to methods of preparing proteins using cells which have been obtained and replicated by single cell deposition as well as compositions which allow the replication of single cells. | 2011-10-13 |
20110250641 | ZWITTERIONIC ACID-LABILE SURFACTANTS AND METHODS OF USE - A compound of the formula: | 2011-10-13 |
20110250642 | Method for Displaying Antibodies - There is disclosed vector designs, constructs and approaches to construct antibody libraries that display antibodies, such as full-length immunoglobulins, single chain antibody (SCA) scFv, or Fab on the host cell surface. There is also disclosed screening approaches to isolate desired antibody binders from above mentioned antibody libraries for selective antibody targets. | 2011-10-13 |
20110250643 | ANTIBODY COMPOSITION-PRODUCING CELL - The present invention relates to a cell for the production of an antibody molecule such as an antibody useful for various diseases having high antibody-dependent cell-mediated cytotoxic activity, a fragment of the antibody and a fusion protein having the Fc region of the antibody or the like, a method for producing an antibody composition using the cell, the antibody composition and use thereof. | 2011-10-13 |
20110250644 | FEED SUPPLEMENT FOR MAMMALIAN CELL CULTURE AND METHODS OF USE - An improved feed supplement for culture of mammalian cells used to produce proteins is provided. The improved supplement is devoid of animal-derived components and protein hydrolysates. The invention also provides methods of using the supplement in production of a therapeutic proteins, such as an antibody. In some embodiments, the antibody is an anti-human IL-23p19 antibody. | 2011-10-13 |
20110250645 | METHODS TO IMPROVE MONOMERIC SUGAR RELEASE FROM LIGNOCELLULOSIC BIOMASS FOLLOWING ALKALINE PRETREATMENT - A method is provided for improving the release of monomeric sugars from alkaline pretreated biomass. The method includes further processing of pretreated biomass and addition of a chemical to the saccharification reaction, which together provides for unexpected release of high levels of monomeric sugars that may be fermented to target products. | 2011-10-13 |
20110250646 | AMMONIA PRETREATMENT OF BIOMASS FOR IMPROVED INHIBITOR PROFILE - Methods for treating biomass for release of fermentable sugars with an improved inhibitor profile are provided. Specifically, a hydrolysate comprising fermentable sugars with an improved inhibitor profile is obtained by saccharification of a reaction product obtained by pretreating biomass with ammonia under suitable reaction conditions. The pretreated biomass reaction product has an acetamide to acetate molar ratio greater than about 1 and an acetyl conversion of greater than 60%. The acetamide to acetate molar ratio is maintained greater than about 1 throughout saccharification. The hydrolysate may be fermented to a target compound. | 2011-10-13 |
20110250647 | Corynebacterium Genus Microorganism Having Ability to Produce N-Acetyl Glucosamine and Method for Producing N-Acetyl Glucosamine or Glucosamine Using the Same - The present invention relates to a microorganism of the | 2011-10-13 |
20110250648 | Compositions And Methods For Inhibiting Terminal Transferase Activity - The present invention relates to systems and methods for amplifying nucleic acid. In particular, systems and methods are provided for inhibiting polymerase based terminal transferase activity within a polynucleotide amplification setting (e.g., polymerase chain reaction). In addition, systems and methods are provided for generating amplified products generated with polynucleotide amplification techniques having reduced 3′ non-templated nucleotide addition. | 2011-10-13 |
20110250649 | PCR-BASED METHOD OF SYNTHESIZING A NUCLEIC ACID MOLECULE - There is provided a method of synthesizing a nucleic acid molecule and in one aspect, the method comprises assembling a full length template nucleic acid molecule by PCR in a PCR reaction mixture comprising a set of assembly oligonucleotides having a first average melting temperature and a set of outer amplification primers having a second average melting temperature that is lower than the first average melting temperature, wherein said assembling comprises subjecting the PCR reaction mixture to a first annealing temperature that is higher than the second average melting temperature and; amplifying the full length template nucleic acid molecule by PCR in the PCR reaction mixture wherein said amplifying comprises subjecting the PCR reaction mixture to a second annealing temperature that permits annealing of the outer amplification primers to the full length template nucleic acid molecule. | 2011-10-13 |
20110250650 | LENTIVIRAL VECTORS FOR THE PREPARATION OF IMMUNOTHERAPEUTICAL COMPOSITIONS - The invention relates to an immunogenic composition comprising a recombinant vector characterized in that it comprises a polynucleotide comprising the cis-acting central initiation region (cPPT) and the cis-acting termination region (CTS), these regions being of retroviral or retroviral-like origin, said vector comprising in addition a defined nucleotide sequence (transgene or sequence of interest) and regulatory signals of retrotranscription, expression and encapsidation of retroviral or retroviral-like origin, wherein the composition is capable of inducing or of stimulating a cell-mediated response for instance a CTL (Cytotoxic T Lymphocytes) response or a CD4 response, against one or several epitopes encoded by the transgene sequence present in the vector. | 2011-10-13 |
20110250651 | Corynebacteria Strain for Enhancement of 5'-Guanosine Monophosphate Productivity and a Method of Producing 5'-Guanosine Monophosphate Using the Same - Disclosed is a method of producing 5′-guanosine monophosphate using a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type, thereby showing improved ATP productivity. Also, a novel microorganism is disclosed. The method comprises: culturing the | 2011-10-13 |
20110250652 | PROCESS FOR PRODUCTION OF AN ENZYMATIC PREPARATION FOR HYDROLYSIS OF CELLULOSE FROM LIGNOCELLULOSIC RESIDUES AND APPLICATION THEREOF IN THE PRODUCTION OF ETHANOL - The process of the present invention is based on the microbial production of enzymes from the growth of the fungus | 2011-10-13 |
20110250653 | L-SUCCINYLAMINOACYLASE AND PROCESS FOR PRODUCING L-AMINO ACID USING IT - The present invention provides a L-succinylacylase consisting of: (a) a protein coded by a gene consisting of a nucleic acid sequence shown in SEQ ID No: 1; (b) a protein consisting of an amino acid sequence shown in SEQ ID No: 2; (c) a protein coded by a polynucleotide which hybridizes under a stringent condition with a nucleic acid sequence which is complementary to the nucleic acid sequence shown in SEQ ID No: 1 and having an L-succinylaminoacylase activity; or (d) a protein which consists of an amino acid sequence where one or several amino acid(s) is/are substituted, deleted, inserted and/or added in the protein consisting of the amino acid sequence shown in SEQ ID No: 2 and has an L-succinylaminoacylase activity. This enzyme is able to produce a sterically bulky unnatural amino acid such as L-tert-leucine etc. which is useful as an intermediate for pharmaceuticals. | 2011-10-13 |
20110250654 | MICROAEROBIC CULTURES FOR CONVERTING GLYCEROL TO CHEMICALS - Glycerol or other reduced carbon sources may be used as a feedstock for the microbial production of chemical products under certain microaerobic conditions. For example, such production may occur under microaerobic or microrespiratory conditions in which electron acceptors are consumed in the reaction as quickly as they are added. In such reactions, the reaction product is at least as reduced as carbon source. Further, during such a reaction, at least some of the carbon source is used to generate cell mass. In addition, microorganisms with modified genomes are provided for carrying out the methods herein. | 2011-10-13 |
20110250655 | Biocatalysts For Manufacturing Duloxetine Alcohol - The present invention relates to novel phenylethanol dehydrogenase mutants, to a method for the manufacture thereof; to coded nucleic acid sequences therefor, to expression cassettes, to vectors and recombinant microorganisms that contain said sequences; to a method for the biocatalytic synthesis of substituted, optically active alcohols and to the use of said mutants; and particularly to a method for manufacturing duloxetine alcohol or duloxetine, comprising a synthesis step catalyzed biocatalytic by said mutants. | 2011-10-13 |
20110250656 | PRODUCTION OF MONASCUS-LIKE AZAPHILONE PIGMENT - The present invention relates to the field of biotechnological production of polyketide based colorants from filamentous fungi, in particular a method for preparing a biomass comprising a | 2011-10-13 |
20110250657 | Processes for Making [R]-Ethyl 4-Cyano-3 Hydroxybutyric Acid - The invention provides novel processes for making ethyl-4-cyano-3-hydroxybutyrate, e.g., (R)-ethyl 4-cyano-3-hydroxybutyric acid, and 4-cyano-3-hydroxybutyric acid. The invention provides protocols for making and 4-cyano-3-hydroxybutyric acid and ethyl-4-cyano-3-hydroxybutyrate by whole cell processes, cell lysate processes, “one pot processes” and “multi-pot” processes using a variety of parameters. | 2011-10-13 |
20110250658 | Recombinant Microalgae Cells Producing Novel Oils - Disclosed herein are obligate heterotrophic microalgae cells containing an exogenous gene. In some embodiments the gene is a sucrose utilization gene, and further disclosed are methods of manufacturing triglyceride oils using sugar cane or sugar beets as a feedstock in a heterotrophic fermentation. In other embodiments the feedstock is depolymerized cellulosic material. Also disclosed are cells that produce medium chain fatty acids at levels not produced in non-recombinant cells of the same species and genus. | 2011-10-13 |
20110250659 | MODIFIED PHOTOSYNTHETIC MICROORGANISMS FOR PRODUCING LIPIDS - This disclosure describes genetically modified photosynthetic microorganisms, e.g., Cyanobacteria, that contain one or more exogenous genes encoding a phospholipase and/or thioesterase, which are capable of producing an increased amount of lipids and/or fatty acids. This disclosure also describes genetically modified photosynthetic microorganisms that contain one or more exogenous genes encoding a diacyglycerol acyltransferase, a phosphatidate phosphatase, and/or an acetyl-CoA carboxylase, which are capable of producing increased amounts of fatty acids and/or synthesizing triglycerides, as well as photosynthetic microorganism comprising mutations or deletions in a glycogen biosynthesis or storage pathway, which accumulate a reduced amount of glycogen under reduced nitrogen conditions as compared to a wild type photosynthetic microorganism. | 2011-10-13 |
20110250660 | METHOD FOR PRODUCING ALDEHYDE FROM CO2 - The invention provides recombinant microorganisms capable of producing isobutyraldehyde using CO | 2011-10-13 |
20110250661 | Methods for gasification of carbonaceous materials - The present disclosure is generally directed to process of gasification of carbonaceous materials to produce synthesis gas or syngas. The present disclosure provides improved methods of gasification comprising: adding one or more carbonaceous materials, adding a molecular oxygen-containing gas, adding a methane-containing gas and optionally adding water or steam into said gasifier. This disclosure is also directed to process of production of one or more alcohols from said syngas via fermentation or digestion in the presence of at least one microorganism. | 2011-10-13 |
20110250662 | Methods for gasification of carbonaceous materials - The present disclosure is generally directed to process of gasification of carbonaceous materials to produce synthesis gas or syngas. The present disclosure provides improved methods of gasification comprising: adding one or more carbonaceous materials, adding a molecular oxygen-containing gas, adding carbon dioxide gas and optionally adding water into said gasifier. This disclosure is also directed to process of production of one or more alcohols from said syngas via fermentation or digestion in the presence of at least one microorganism. | 2011-10-13 |
20110250663 | METHODS AND COMPOSITIONS RELATED TO FATTY ALCOHOL BIOSYNTHETIC ENZYMES - Compositions and methods for producing fatty acid derivatives using recombinant microorganisms are described herein. | 2011-10-13 |
20110250664 | YEAST HAVING IMPROVED ETHANOL YIELD - The present invention provides for a genetically-altered haploid yeast cell characterized by reduced activity or expression of FPS1, reduced activity or expression of glycerol-3-phosphate dehydrogenase-1 (GPD1), reduced activity or expression of glycerol-3-phosphate dehydrogenase-2 (GPD2), and increased expression of glutamate synthase (GLT1), wherein the reduced activity or expression, and the increased expression, is relative to expression or activity in a wildtype yeast strain, e.g., | 2011-10-13 |
20110250665 | ETHANOL PRODUCTION PROCESS AND YEAST FOR ETHANOL PRODUCTION - According to the present invention, ethanol production is carried out with the use of cellulose or cellobiose as a starting material at low cost. The method of the present invention comprises the steps of culturing a microorganism that is classified as a species selected from the group consisting of | 2011-10-13 |
20110250666 | SHORT CHAIN VOLATILE HYDROCARBON PRODUCTION USING GENETICALLY ENGINEERED MICROALGAE, CYANOBACTERIA OR BACTERIA - The present invention provides methods and compositions for producing isoprene hydrocarbons from microalgae, cyanobacteria, and photosynthetic and non-photosynthetic bacteria. | 2011-10-13 |
20110250667 | FOSSIL FUEL-FREE PROCESS OF LIGNOCELLULOSIC PRETREATMENT WITH BIOLOGICAL HYDROGEN PRODUCTION - The invention provides an isolated haloalkaliphilic microorganism designated as strain sapolanicus belonging to the genus | 2011-10-13 |
20110250668 | PROTEIN FOR CONSTRUCTING PROTEIN COMPLEX FROM CLOSTRIDIUM THERMOCELLUM, AND USE THEREOF - It is an object to provide a protein having a dockerin, which is suited to production in yeasts and other eukaryotic microorganism in which sugar chain modification is predicted, and which provides excellent cohesin-dockerin binding ability, along with a use thereof. The present invention uses, as a protein for constructing a protein complex using a scaffolding protein having a type I cohesin from | 2011-10-13 |
20110250669 | METHOD AND APPARATUS FOR SELECTIVELY TARGETING SPECIFIC CELLS WITHIN A CELL POPULATION - This invention provides a method and apparatus for selectively identifying, and targeting with an energy beam, specific cells within a cell population, for the purpose of inducing a response in the targeted cells. Using the present invention, every detectable cell in a population can be identified and affected, without substantially affecting non-targeted cells within the mixture. | 2011-10-13 |
20110250670 | LIGHT ENERGY-INDUCED STABILITY OF BIOMATERIALS - Disclosed are methods and apparatuses for stabilizing labile biomolecules in an aqueous solution without the use of chemicals. For example, some embodiments involve exposing an aqueous solution of a labile biomolecule, such as a protein, to light energy to stabilize the biomolecule in the solution. | 2011-10-13 |
20110250671 | GLUCOSE DEHYDROGENASE AND METHOD FOR PRODUCING THE DEHYDROGENASE - A DNA encoding a glucose dehydrogenase enzyme having high substrate specificity, can be produced at a low cost, is not affected by oxygen dissolved in a measurement sample and, in particular, has superior thermal stability is described. Cells transformed with the DNA encoding the glucose dehydrogenase enzyme may be used to produce the glucose dehydrogenase by culturing the transformants to produce glucose dehydrogenase as an expression product of the DNA, and collecting the product. | 2011-10-13 |
20110250672 | MUTANT DNA POLYMERASES AND USES THEROF - The present invention relates to mutant DNA polymerases which incorporate dideoxynucleotides with about the same efficiency as deoxynucleotides. The present invention also related to mutant DNA polymerases which also have substantially reduced 5′-to-3′ exonuclease activity or 3′-to-5′ exonuclease activity. The invention also relates to DNA molecules coding for the mutant DNA polymerases, and hosts containing the DNA molecules. | 2011-10-13 |
20110250673 | FACILITATED PROCESS FOR PURIFICATION OF PROTEINS - A two-stage heat treatment process is provided to improve the processability of recombinant microbial biomass comprising an enzyme having perhydrolytic activity. More specifically, a process is provided to treat the recombinant microbial biomass comprising a | 2011-10-13 |
20110250674 | CELLULASE VARIANTS - The present invention relates to a method for improving the properties of a cellulolytic enzyme by amino acid substitution, deletion or insertion, the method comprising the steps of:
| 2011-10-13 |
20110250675 | Virus-Like Particle Mediated Cellular Delivery - The invention provides compositions and methods for delivering compounds to cells. The invention is directed, in part, to virus-like particles which contain biological materials such as carbohydrates, proteins and nucleic acids. The invention is also directed, in part, to methods for delivering compounds to cells involving contacting cells with the compounds under conditions which allow for uptake of the compounds by cells and release of the compounds into the cells which take it up. | 2011-10-13 |
20110250676 | Composition and Method for Bioremediation of Deicing Fluids - The present invention is a kit and method for bioremediation of deicing fluids containing glycol. Using a combination | 2011-10-13 |
20110250677 | Apparatus for Assessing the Effectiveness of a Sterilization Process - A device useful in determining the efficacy of a chemical sterilization process includes a dead end cavity closed by an access cap having a port coupled to a challenge tube defining the only path by which a substantial quantity of sterilant can reach the cavity. A biological indicator is located within the cavity and a chemical indicator is also provided. These indicators, and particularly the biological indicator, provide an indication of whether chemical sterilant would reach all interior exposed surfaces of a load in sufficient concentrations to adequately sterilize the load. | 2011-10-13 |
20110250678 | SYSTEM FOR PRODUCING GAS FROM ORGANIC WASTE - A system for producing gas from organic waste includes a pretreatment unit, which crushes organic waste; an oxidation unit, which oxidizes the crushed organic waste in an oxidation bath; an oxidation unit, which converts the oxidized organic waste into fluid by anaerobic digestion; and a stabilization unit, which divides the fluid into gas and liquid fertilizer when the fluid is supplied into a fluid-stabilizing bath. The oxidation bath has a transparent safety window, a coupler, a first pipe coupled to the coupler and connected to the oxidation pump, a second pipe, a pit formed in a bottom of the oxidation bath. An inorganic-material-discharging unit has one side seated in the pit and the other side exposed from above. A mixer is coupled to a lower inside wall of the oxidation bath corresponding to the pit, and includes first blades coupled to a mixing motor. | 2011-10-13 |
20110250679 | Methods and Compositions for High-Resolution Micropatterning for Cell Culture - Composite structures and methods for generating micropatterned materials suitable for use in cell culture applications are disclosed. The improvement of these compositions and methods over the prior art is based on the unexpected discovery that minor chemical modifications can be introduced to greatly enhance the adherence and/or stability of a cell-adhesive material. The micropatterned materials are inexpensive to manufacture, have long shelf-life, and are stable for prolonged periods of time under cell-culture conditions. Moreover, biologists can use these micropatterned substrates with the same ease as conventional cultureware and without the need for special sample preparation. | 2011-10-13 |
20110250680 | AUTOMATED SYSTEM FOR THE LYSIS OF MICROORGANISMS PRESENT IN A SAMPLE, FOR EXTRACTION AND FOR PURIFICATION OF THE NUCLEIC ACIDS OF SAID MICROORGANISMS FOR PURPOSES OF ANALYSIS - The present invention relates to, among other things, a device for collecting airborne microorganisms, said device having:
| 2011-10-13 |
20110250681 | Fc Variants with Optimized Properties - The present invention relates to Fc variants with optimized properties, methods for their generation, Fc polypeptides comprising Fc variants with optimized properties, and methods for using Fc variants with optimized properties. | 2011-10-13 |
20110250682 | FORMATION OF NEUROMUSCULAR JUNCTIONS IN A DEFINED SYSTEM - A method for forming neuromuscular junctions includes forming functional neuromuscular junctions between motoneurons and muscle cells by co-culturing one or more human motoneurons and one or more rat muscle cells in a substantially serum-free medium. A synthetic mammalian neuromuscular junction includes a human motoneuron functionally linked to a rat muscle cell in a substantially serum-free medium. An artificial substrate may be used to support the one or more neuromuscular junctions. | 2011-10-13 |
20110250683 | Thermophilic and thermoacidophilic sugar transporter genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods - Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from | 2011-10-13 |
20110250684 | METHOD FOR PRODUCING NEURAL STEM CELLS - In order to provide a method for producing neural stem cells easily and quickly by inducing differentiation of somatic cells directly into neurospheres, dedifferentiation factors are introduced into somatic cells, which are then cultured in suspension in the presence of growth factors to produce the neurospheres, thereby allowing the neural stem cells to be produced quickly without establishing iPS cells. | 2011-10-13 |
20110250685 | COMPOSITIONS AND METHODS FOR ENHANCING CELLULAR TRANSPORT OF BIOMOLECULES - The present invention discloses compositions and methods for delivery of biomolecules into cells. Compositions comprise peptidomimetic macrocycles complexed or conjugated to biomolecules such as nucleic acids. | 2011-10-13 |
20110250686 | NOVEL HEPATOCYTE-LIKE CELLS AND HEPATOBLAST-LIKE CELLS DERIVED FROM hBS CELLS - The present invention relates to a novel hepatocyte-like cell population derived from hBS cells and to the potential use of such heopatocyte-like cells in e.g. medical treatment, drug screening and toxicity testing. Furthermore, the invention relates to 5 hepatoblast-like cells that may have suitable characteristics so that they can be used for the same applications as the hepatocyte-like cells and that furthermore may be used in in vitro studies of hepatogenesis such as early hepatogenesis or hepatoregenerative disorders. Both the hepatocyte-like and the hepatoblast-like cells according to the invention express drug transporter and/or drug metabolising 10 characteristics either at the gene or protein expression level. | 2011-10-13 |
20110250687 | Cell adhesion inhibitor (CAI) with combination growth factors mobilization of peripheral blood mononuclear cells for CAI derived dendritic cell (CdDC) preparation and dendritic cell vaccine preparations generated from CdDC - Disclosed is a method to recover a dendritic cell rich mixture from peripheral blood mononuclear cells (PBMC) mobilized with one or more cell adhesion inhibitors (CAI) for the preparation of a dendritic cell vaccine. The CAI derived dendritic cell rich mixture (CdDC) from PBMC can either be used alone or better still, be induced into dendritic vaccine specific preparations with the addition or modification with different antigens and methodologies of immunological induction methods known to the art. These CAI derived dendritic vaccines can then be used, but not exclusively so, in the treatment of cancer and infectious diseases. In order to achieve the best immature and mature dendritic cell rich mixture, peripheral blood cells mobilization may be achieved by administering, simultaneously or in sequence, to an individual one or more of a combination of different chemical compounds, hormones, growth factors etc. prior to PBMC collection with one or more of cell adhesion inhibitors such as a CXCR | 2011-10-13 |
20110250688 | Three Dimensional Tissue Generation - Methods and materials for generating a three-dimensional tissue construct are provided. The method comprises (a) providing a tissue scaffold; (b) providing isolated smooth muscle cells; (c) suspending the isolated cells in hydrogel; (d) ejecting the cell/hydrogel suspension from a printer onto the tissue scaffold; and (e) incubating the cells on the scaffold in media at 37° C. | 2011-10-13 |
20110250689 | Multilayer preform obtained by electro-spinning, method for producing a preform as well as use thereof - The invention relates a multilayer preform obtained by electro-spinning, which preform is suitable as a scaffold for a prosthesis, which preform comprises at least one layer of microfibres and at least one layer of nanofibres, wherein the pore size of the at least one layer of microfibres is in the range of 1-300 micrometre and in that the pore size of the at least one layer of nanofibres is in the range of 1-300 micrometre. The present invention also relates to a method of producing said preform. The present invention also relates to the use of the present preform as a substrate for growing human or animal tissue thereon. The present invention furthermore relates to a method for growing human or animal tissue on a substrate, wherein the present preform is used as the substrate. | 2011-10-13 |
20110250690 | Microfluidic Embryo and Gamete Culture Systems - A robotic microfluidic incubator system has a thin transparent sidewall and close proximity of the embryo/oocyte/cultured cells to the sidewall allow close approach of a side view microscope with adequate focal length for mid to high power. This arrangement permits microscopic examination of multiple culture wells when arranged in rows (linear or along the circumference of a carousel). Manual or automated side to side movement of the linear well row, or rotation of the carousel, allows rapid inspection of the contents each well. Automated systems with video capability also allow remote inspection of wells by video connection or Internet connection, and automated video systems can record oft-hours inspections or time lapse development in culture (i.e. embryo cell division progression, or axon growth in neuron cell cultures). | 2011-10-13 |
20110250691 | CULTURE MEDIUM FOR MYOBLASTS, PRECURSORS THEREOF AND DERIVATIVES THEREOF - This application relates to a serum-free culture medium that enables the proliferation of cell of the myogenic lineage while maintaining their ability to differentiate into functional muscle cells. Also contemplated herewith are method of culturing cells of the myogenic lineages and uses of the cultured cells for the treatment or the alleviation of symptoms of a muscular deficiencies. | 2011-10-13 |
20110250692 | METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS - The present invention relates to a method for producing mammalian induced pluripotent stem cells, comprising introducing mammal-derived reprogramming factors comprising Oct3/4 and Nanog, or nucleic acids encoding Oct3/4 and Nanog, into mammal-derived somatic cells and thereby inducing induced pluripotent stem cells from the somatic cells, wherein the reprogramming factors comprise neither Sox2 nor nucleic acid encoding Sox2. | 2011-10-13 |
20110250693 | INTERGENIC REGIONS AS INSERTION SITES IN THE GENOME OF MODIFIED VACCINIA VIRUS ANKARA (MVA) - The present invention relates to novel insertion sites useful for the integration of exogenous sequences into the Modified Vaccinia Ankara (MVA) virus genome. The present invention further provides plasmid vectors to insert exogenous DNA into the genome of MVA. Furthermore, the present invention provides recombinant MVA comprising an exogenous DNA sequence inserted into said new insertion site as medicine or vaccine. | 2011-10-13 |
20110250694 | EUKARYOTIC EXPRESSION VECTORS RESISTANT TO TRANSGENE SILENCING - The present invention relates to recombinant DNA molecules such as plasmids, non-viral vectors, viral vectors and hybrids thereof, and more particularly to vector modifications that improve expression of said DNA molecules in cell lines and organisms. | 2011-10-13 |
20110250695 | METHOD, STRUCTURE, DEVICE, KIT AND SYSTEM FOR THE AUTOMATED ANALYSIS OF LIQUID SAMPLES - A method for the automated analysis of liquid samples using at least one microfluidic structure is disclosed as well as microfluidic structures, a device having at least one of the microfluidic structures, a kit and a system including such microfluidic device. In one embodiment, the method may comprise: transferring said sample into a first fluid reservoir which is in fluid communication with a second fluid reservoir by a flow channel; spinning said microfluidic structure so as to transport said sample into one or more dead-end recesses or chambers; transferring a control fluid into the structure which generates a barrier to flow and diffusion of said sample contained in said one or more dead-end recesses or chambers; and analyzing said sample contained in said one or more dead-end recesses or chambers. | 2011-10-13 |
20110250696 | Process for High Concentration Cation Exchange Metathesis - Provided is a method for high concentration cation exchange metathesis of divalent ions such as calcium with univalent ions such as sodium or potassium. Due to the difference between ionic valences between the exchanged ions, the provided process behavior is strongly dependent upon the selection of resin properties and to total solution normality. A combination of resin properties and solution normality is provided to achieve the cation exchange. | 2011-10-13 |
20110250697 | NON-NATURALLY OCCURRING DNA SEQUENCES - DNA compositions having nucleotide sequences that do not occur in nature. Also provided are fluorescently labeled DNA molecules and complementary DNA on solid substrates, such as microspheres. | 2011-10-13 |
20110250698 | METHODS OF NUCLEIC ACID TARGET CAPTURE - Methods for efficiently capturing a target nucleic acid from a sample by using a mixture that contains a capture probe specific for the target nucleic acid, the target nucleic acid, and a denaturant chemical, which mixture is incubated at elevated temperature for a short time, are disclosed. Compositions that include a capture probe that specifically binds to a target nucleic acid and a denaturant chemical, which when mixed with the target nucleic acid and incubated at elevated temperature for a short time, promote efficient hybridization of the capture probe and target nucleic acid are disclosed. | 2011-10-13 |
20110250699 | Fluorescent Dye Compounds, Conjugates and Uses Thereof - The present teachings generally relate to fluorescent dyes, linkable forms of fluorescent dyes, energy transfer dyes, reagents labeled with fluorescent dyes and uses thereof. | 2011-10-13 |
20110250700 | Methods for Sequencing Individual Nucleic Acids Under Tension - The invention provides apparatuses and methods of use thereof for sequencing nucleic acids subjected to a force, and thus considered under tension. The methods may employ but are not dependent upon incorporation of extrinsically detectably labeled nucleotides. | 2011-10-13 |
20110250701 | NOVEL APPLICATION OF AIMP1 POLYPEPTIDE - The present invention relates to a novel use of AIMP1 polypeptide, more particularly to a composition for diagnosis of arthritis comprising an antibody against AIMP1, a kit for diagnosis comprising the same, a method for diagnosis of arthritis comprising: acquiring a specimen from a subject; and detecting AIMP1 polypeptide included in the specimen, and an antibody against the AIMP1 polypeptide for diagnosis of arthritis. The present invention provides a composition for diagnosis of arthritis including an antibody against AIMP1 polypeptide as a novel diagnosis marker of arthritis, a kit for diagnosis including the same, a method for diagnosis of arthritis comprising: acquiring a specimen from a subject; and detecting AIMP1 polypeptide included in the specimen, and an antibody against the AIMP1 polypeptide for diagnosis of arthritis. The composition, kit for diagnosis, method for diagnosis and antibody against the AIMP1 polypeptide may be used to diagnose arthritis early since they allow easy diagnosis of arthritis using a specimen from the patient. | 2011-10-13 |
20110250702 | ISOLATED PEPTIDES OF RABBIT FACTOR VII - The present disclosure relates to peptides isolated from rabbit factor VII and to the use of thereof for the generation of antibodies specifically directed against the latter. The disclosure also relates to the use of antibodies directed against rabbit factor VII for the detection or purification of rabbit factor VII, specifically when said rabbit factor VII is in a biological sample which also contains human factor VII. | 2011-10-13 |
20110250703 | IL1RL-1 AS A CARDIOVASCULAR DISEASE MARKER AND THERAPEUTIC TARGET - This invention pertains to methods and compositions for the diagnosis and treatment of cardiovascular conditions. More specifically, the invention relates to isolated molecules that can be used to diagnose and/or treat cardiovascular conditions including cardiac hypertrophy, myocardial infarction, stroke, arteriosclerosis, and heart failure. | 2011-10-13 |
20110250704 | Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification - The invention features compositions and methods for site-specific modification of proteins by incorporation of an aldehyde tag. Enzymatic modification at a sulfatase motif of the aldehyde tag through action of a formylglycine generating enzyme (FGE) generates a formylglycine (FGly) residue. The aldehyde moiety of FGly residue can be exploited as a chemical handle for site-specific attachment of a moiety of interest to a polypeptide. | 2011-10-13 |
20110250705 | NANOPORE CAPTURE SYSTEM - A nanopore capture system may include a material configured to pass through a nanopore device in a controlled manner based upon its interaction with the nanopore device. The system may also include a capture mechanism connected to one end of the material. The capture mechanism may be configured to catch a particular type of molecule while ignoring other types of molecules. The system may also include a controller to manipulate and/or detect the particular type of molecule. | 2011-10-13 |
20110250706 | METHOD OF FABRICATING MEMS, NEMS, PHOTONIC, MICRO- AND NANO-FABRICATED DEVICES AND SYSTEMS - An improved method for the fabrication of Micro-Electro-Mechanical Systems (MEMS), Nano-Electro-Mechanical Systems (NEMS), Photonics, Nanotechnology, 3-Dimensional Integration, Micro- and Nano-Fabricated Devices and Systems for both rapid prototyping development and manufacturing is disclosed. The method includes providing a plurality of different standardized and repeatable process modules usable in fabricating the devices and systems, defining a process sequence for fabricating a predefined one of the devices or systems, and identifying a series of the process modules that are usable in performing the defined process sequence and thus in fabricating the predefined device or system. | 2011-10-13 |
20110250707 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE - A method of manufacturing a semiconductor device may include, but is not limited to the following processes. A first group identifier allocated to a first group of semiconductor wafers is detected. The first group of semiconductor wafers includes a first semiconductor wafer to be processed first among the first group. A first processor of a plurality of processors, which process respective ones of the first group of semiconductor wafers, are determined based on the first group identifier. The first processor is used for processing the first semiconductor wafer. The first semiconductor wafer is supplied to the first processor. | 2011-10-13 |
20110250708 | METHOD OF MANUFACTURING ORGANIC LIGHT EMITTING DIODE ARRAYS AND SYSTEM FOR ELIMINATING DEFECTS IN ORGANIC LIGHT EMITTING DIODE ARRAYS - A method for manufacturing an organic light emitting diode (OLED) array is provided that includes applying an energizing signal to at least one of the OLED pixels in the array. The energizing signal exceeds a threshold level. The method also includes reducing the energizing signal and identifying an OLED in the array that continues to remain energized. The method further includes irradiating the identified OLED to degrade the organic material in the OLED. A method of performing quality control in a manufacturing process of an OLED array is provided. The method includes determining an intensity, a time and a wavelength of radiation sufficient to render an OLED of the OLED array inoperative by degrading organic material in the OLED. A system of performing quality control in a manufacturing process of an OLED array is provided. A computer-readable medium having stored thereon computer-executable instructions is provided. | 2011-10-13 |
20110250709 | METHOD AND APPARATUS FOR MANUFACTURING THIN FILM PHOTOELECTRIC CONVERSION MODULE - A method for manufacturing a thin film photoelectric conversion module comprising the steps of: (A) forming a plurality of divided strings by dividing a string, in which thin film photoelectric conversion elements provided by sequentially laminating a first electrode layer, a photoelectric conversion layer and a second electrode layer on the surface of an insulating substrate are electrically connected in series, into a plurality of strings by dividing grooves, electrically insulating and separating the first electrode layer and the second electrode layer one from the other and extending in a serial connection direction; and (B) performing reverse biasing by applying a reverse bias voltage to each of thin film photoelectric conversion elements of the divided string. | 2011-10-13 |
20110250710 | ELECTRICAL ALIGNMENT MARK SET AND METHOD FOR ALIGNING WAFER STACK - An electrical alignment mark set and the method for using the same is disclosed. The electrical alignment mark set includes at least a top mark and a bottom mark. The top mark includes multiple pads disposed on a top wafer and having first pads and second pads, and a monitoring via electrically connected to the first pads. The bottom mark includes a first bottom pad corresponding to the monitoring via and a second bottom pad corresponding to the second pads. Further the first bottom pad and the second bottom pad are electrically connected to each other so that the monitoring via maybe electrically connected to the second pads by means of the first bottom pad when the top mark and the bottom mark are aligned with each other. | 2011-10-13 |
20110250711 | METHOD OF MANUFACTURING LIGHT-EMITTING DEVICE - A method of manufacturing a light-emitting device includes forming a planar board that includes a plurality of first metallic plates and a plurality of second metallic plates continuously connected by a resin, by use of a positioning frame including a plurality of first concave portions and a plurality of second concave portions, mounting a plurality of light-emitting diode elements on the planar board, and sealing the light-emitting diode elements collectively, thereby producing a plurality of light-emitting devices. | 2011-10-13 |
20110250712 | COLOR ELECTROPHORETIC DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME - According to an embodiment of the present invention, a method for manuafacturing a color electrophoretic display device includes forming a thin film transistor (TFT) array substrate including a display region, wherein a plurality of pixel regions is defined in a matrix, and alignment keys are provided at the outside of the display region, forming an electrophoretic layer including a micro capsule layer formed so as to correspond to the display region of the TFT array substrate, and forming a color filter layer on an outer surface of the electrophoretic layer using the alignment keys so as to correspond to the respective pixel regions of the display region. | 2011-10-13 |
20110250713 | ACTIVE MATRIX SUBSTRATE MANUFACTURING METHOD AND LIQUID CRYSTAL DISPLAY DEVICE MANUFACTURING METHOD - Provided is an active matrix substrate manufacturing method, including the steps of: selectively forming a laminated structure pattern, by forming the laminated structure on a glass substrate ( | 2011-10-13 |
20110250714 | NITRIDE SEMICONDUCTOR AND METHOD FOR MANUFACTURING SAME - A nitride semiconductor includes: a substrate having a major surface including a first crystal polarity surface and a second crystal polarity surface different from the first crystal polarity surface; and a single polarity layer provided above the major surface and having a single crystal polarity. | 2011-10-13 |
20110250715 | METHODS FOR FORMING ANTI-REFLECTION STRUCTURES FOR CMOS IMAGE SENSORS - Protuberances, having vertical and lateral dimensions less than the wavelength range of lights detectable by a photodiode, are formed at an optical interface between two layers having different refractive indices. The protuberances may be formed by employing self-assembling block copolymers that form an array of sublithographic features of a first polymeric block component within a matrix of a second polymeric block component. The pattern of the polymeric block component is transferred into a first optical layer to form an array of nanoscale protuberances. Alternately, conventional lithography may be employed to form protuberances having dimensions less than the wavelength of light. A second optical layer is formed directly on the protuberances of the first optical layer. The interface between the first and second optical layers has a graded refractive index, and provides high transmission of light with little reflection. | 2011-10-13 |
20110250716 | SOLID-STATE IMAGE PICKUP DEVICE AND METHOD FOR MANUFACTURING SAME - In a solid-state image pick up device, a first conduction type semiconductor layer which has a first surface side. A second surface side which is located the opposite side of the first surface side and an image sensor area. A photo-conversion area which is configured in the first surface side and charges electron by photoelectric conversion. A first diffusion area of second conduction type for isolation, wherein the first diffusion area surrounds the photo-conversion area and extends from the first surface side to the middle part of the semiconductor layer and a second diffusion area of second conduction type for isolation, wherein the second diffusion area extends from the second surface side to the bottom of the first diffusion layer. | 2011-10-13 |
20110250717 | SOLID-STATE IMAGING DEVICE AND METHOD FOR MANUFACTURING THE SAME - A solid-state imaging device having a high sensitivity and a structure in which a miniaturized pixel is obtained, and a method for manufacturing the solid-state imaging device in which an interface is stable, a spectroscopic characteristic is excellent and which can be manufactured with a high yield ratio are provided. The solid-state imaging device includes at least a silicon layer formed with a photo sensor portion and a wiring layer formed on the front-surface side of the silicon layer, and in which light L is made to enter from the rear-surface side opposite to the front-surface side of the silicon layer and the thickness of the silicon layer | 2011-10-13 |
20110250718 | LAMINATION AS A MODULAR APPROACH FOR BUILDING ORGANIC PHOTOSENSITIVE DEVICES - There is disclosed a modular lamination approach for processing organic photosensitive devices that allows the individual processing of device components, that once processed are brought together in a final step to make electrical contact. The disclosed method of preparing a laminated photosensitive device having at least one donor-acceptor heterojunction comprises: preparing a top electrode by depositing a functional material on a flexible substrate, such as an elastomer; optionally processing the functional material to obtain desired properties prior to lamination; preparing a bottom portion by depositing a second functional material over a substrate; optionally processing the second functional material to obtain desired properties prior to lamination; and coupling the top electrode to said bottom portion to form a laminated photosensitive device. | 2011-10-13 |
20110250719 | Organic Semiconductors - An organic semiconducting compound comprising the structure of formula (I): | 2011-10-13 |
20110250720 | THRU SILICON ENABLED DIE STACKING SCHEME - A die to die bonding system and method includes an upper die having a front side, a back side, and a fully filled thru silicon via, a portion of the fully filled thru silicon via protruding from the back side of the upper die. A lower die includes a front side, a back side, and a partially filled thru silicon via formed to define a via opening exposed to the front side of the die, a portion of the partially filled thru silicon via protruding from the back side of the lower die. An interconnect bonds an outer surface of the protruding portion of the upper die thru silicon via with an inner surface of via opening in the lower die. | 2011-10-13 |
20110250721 | STACKED AND SHIELDED PACKAGES WITH INTERCONNECTS - Embodiments include methods for forming a stacked die package with a first die, first active circuitry on an upper surface of the first die, and a first conductive pattern on the first active circuitry. The stacked die package further includes a second die stacked over the first die, where the first die is wider than the second die in a cross-section of the stacked die package, and second active circuitry is present on an upper surface of the second die. The stacked die package further includes a mold compound disposed on the first die, where the mold compound encapsulates the second die. Electrical connections are formed from the top surface of the mold compound to the first conductive pattern and the second active circuitry, and a conductive pattern on the top surface of the mold compound provides a continuous electrical connection between upper ends of the electrical connections. | 2011-10-13 |
20110250722 | INVERSE CHIP CONNECTOR - A system for connecting a first chip to a second chip having a post on the first chip having a first metallic material, a recessed wall within the second chip and defining a well within the second chip, a conductive diffusion layer material on a surface of the recessed wall within the well, and a malleable electrically conductive material on the post, the post being dimensioned for insertion into the well such that the malleable electrically conductive material will deform within the well and, upon heating to at least a tack temperature for the malleable, electrically conductive material, will form an electrically conductive tack connection with the diffusion layer to create an electrically conductive path between the first chip and the second chip. | 2011-10-13 |
20110250723 | MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE - In an embodiment, an insulating film is formed over a flat surface; a mask is formed over the insulating film; a slimming process is performed on the mask; an etching process is performed on the insulating film using the mask; a conductive film covering the insulating film is formed; a polishing process is performed on the conductive film and the insulating film, so that the conductive film and the insulating film have equal thicknesses; the conductive film is etched, so that a source electrode and a drain electrode which are thinner than the conductive film are formed; an oxide semiconductor film is formed in contact with the insulating film, the source electrode, and the drain electrode; a gate insulating film covering the oxide semiconductor film is formed; and a gate electrode is formed in a region which is over the gate insulating film and overlaps with the insulating film. | 2011-10-13 |
20110250724 | MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE - An embodiment is a manufacturing method of a semiconductor device including the steps of forming a first insulating film; forming a first mask over the first insulating film; performing a slimming process on the first mask to form a second mask; performing an etching process on the first insulating film using the second mask to form a second insulating film; forming a first conductive film covering the second insulating film; performing a polishing process on the first conductive film and the second insulating film to form a third insulating film, a source electrode, and a drain electrode having equal thicknesses; forming an oxide semiconductor film over the third insulating film, the source electrode, and the drain electrode; forming a gate insulating film over the oxide semiconductor film; and forming a gate electrode in a region which is over the gate insulating film and overlaps with the third insulating film. | 2011-10-13 |
20110250725 | METHOD OF FABRICATING GATE ELECTRODE USING A TREATED HARD MASK - A method for fabricating an integrated device is disclosed. A polysilicon gate electrode layer is provided on a substrate. In an embodiment, a treatment is provided on the polysilicon gate electrode layer to introduce species in the gate electrode layer and form an electrically neutralized portion therein. Then, a hard mask layer with limited thickness is applied on the treated polysilicon gate electrode layer. A tilt angle ion implantation is thus performing on the substrate after patterning the hard mask layer and the treated polysilicon gate electrode to from a gate structure. | 2011-10-13 |