41st week of 2012 patent applcation highlights part 30 |
Patent application number | Title | Published |
20120257995 | Submersible pump and motor rotation indication circuit - This patent addresses a need to be able to tell in which direction of rotation an electric motor is turning when connected to a pump, and in particular, a submersible pump where the direction of the motor shaft is not installed where visual observance of the direction of rotation is possible. This patent covers the modification of any existing motors or pumps to include any device, circuit, or change to sense, measure, or pick up the direction of rotation of an electric pump or motor for the purpose of knowing the direction the motor or pump is turning when operating or bumped for observation. | 2012-10-11 |
20120257996 | VEHICLE A/C COMPRESSOR ASSEMBLY - A vehicle a/c compressor assembly for a hybrid or electric vehicle includes an electric motor housing, an AC electric motor in the electric motor housing, a compressor housing and a compressor in the compressor housing. The AC electric motor is drivingly coupled to the compressor exterior to the motor housing and the compressor housing. | 2012-10-11 |
20120257997 | Air Compressor - An air compressor includes a compressor body, an electric motor, and a gear mechanism that transmits power of the electric motor to the compressor body to prevent intrusion of dust into a casing of the electric motor for improving reliability. In the example in which a gear casing, a load side casing and a seal cover that define the internal space of the gear casing and the internal space of an electric motor main casing, and a non-contact type visco seal provided to a gap in a portion where a rotating shaft of the electric motor penetrates through the load side casing are provided, a communication hole that communicates between a gap from the visco seal toward the electric motor in the load side casing and seal cover and the outside of the air compressor not through the internal space of the electric motor main casing is formed. | 2012-10-11 |
20120257998 | RUNNER WITH INTEGRAL IMPELLOR PUMP - In aspects, the present disclosure provides an apparatus for handling axial thrust in rotating equipment. The apparatus may include a thrust bearing and a runner having a contact surface engaging the thrust bearing. The runner may include passages extending between the contact surface and an opposing surface of the runner. The apparatus may further include a lock ring assembly that has channels in communication with the passages of the runner. In certain embodiments, one or more cavities may be formed on the contact surface of the runner. The cavities may be in communication with the internal passages of the runner. In aspects, the present disclosure provides a method for handling axial thrust in a pump assembly. The pump assembly may include a thrust bearing assembly that may include a runner having a contact surface engaging a thrust bearing pad. The method may include flowing a lubricating fluid to the contact surface using at least one internal passage formed in runner. | 2012-10-11 |
20120257999 | FAN ASSEMBLY AND FAN DEVICE THEREOF - A fan assembly and its fan device are disclosed herein. The fan device includes a housing, a fan body disposed in the housing, a connector electrically connected with the fan body, and a fixing cover detachably assembled to the housing. The fixing cover includes a connecting structure fitting a type of the connector for positioning the connector on the fixing cover. | 2012-10-11 |
20120258000 | System and Method for Monitoring Pump Lining Wear - A system for monitoring wear of pump casing liners is disclosed. The system may include a wear sensor disposed in proximity to the pump casing liner so that the sensor wears at substantially the same rate as the lining. The wear sensor may include a plurality of circuit loops having different lengths. As the pump casing liner and the sensor wear during use, the plurality of circuit loops are sequentially breached. A control system monitors the signals from the plurality of circuit loops to develop liner wear information. This information is employed to signal a user when one or more predetermined wear thresholds are exceeded. Other embodiments are described and claimed. | 2012-10-11 |
20120258001 | Progressing Cavity Pump/Motor - A progressing cavity pump/motor includes a stator ( | 2012-10-11 |
20120258002 | ELECTRIC MACHINE - A three-phase, high voltage motor for use in a scroll compressor includes a stator core having an annular rim and a plurality of teeth extending radially inward from the rim. Aluminum windings are wrapped around teeth of the plurality of teeth of the stator core. The windings are spaced 120 electrical degrees from each other. The motor further includes a rotor body that is rotatably mounted inside the stator core and includes an external surface facing the stator core. | 2012-10-11 |
20120258003 | SCROLL COMPRESSOR WITH SPRING TO ASSIST IN HOLDING SCROLL WRAPS IN CONTACT - An electric motor drives a shaft to cause one scroll member to orbit relative to another scroll member. The shaft has an eccentric pin extending upwardly into a slider block. The eccentric pin is further provided with a generally flat drive surface, with clearance provided between the bore of the slider block and an outer periphery of the eccentric pin such that the slider block can move relative to the eccentric pin. The slider block extends upwardly into a boss extending away from the base of one scroll member wrap. A spring is positioned to bias the one scroll wrap toward the other scroll member wrap. The spring is positioned between the eccentric pin and the bore of the slider block. | 2012-10-11 |
20120258004 | SCROLL COMPRESSOR - A compressor may include a shell assembly, a first scroll member located within the shell assembly and including a first end plate and a first spiral wrap extending from the first end plate, and a second scroll member located within the shell assembly, supported for orbital movement relative to the first scroll member and including a second end plate and a second spiral wrap extending from the second end plate and meshingly engaged with the first spiral wrap to form compression pockets. The first scroll member may define a fluid injection port and the second scroll member may define a passage in communication with the fluid injection port and at least one of the compression pockets to provide pressurized vapor from the fluid injection port to the at least one of the compression pockets. | 2012-10-11 |
20120258005 | SINGLE-SCREW COMPRESSOR - A single-screw compressor includes a screw rotor, a cylinder wall in which the screw rotor is rotatably accommodated, a driving mechanism which variably drives the screw rotor according to a load, and a slide valve which is provided in a slide groove formed in the cylinder wall. The slide valve faces an outer circumferential surface of the screw rotor to be movable in an axial direction, and to adjust a discharge start position by being moved in the axial direction according to the operating capacity. A discharge side end surface of the slide valve extends in a direction corresponding to a screw land of the screw rotor to which the discharge side end surface faces when the slide valve is moved to a position corresponding to a part load operation state. | 2012-10-11 |
20120258006 | External Gear Pump for Hot Cooking Oil - An overhung external spur gear positive displacement pump for hot oil or deep fryer applications is disclosed. The external gear pump includes a casing that includes a through bore for accommodating a drive shaft that leads to a pump chamber that accommodates a drive gear and a driven gear. The casing further includes a recess connected to the pump chamber for accommodating a stationary pin. The casing also includes a proximal end coupled to a prime mover and a distal end coupled to a head. The gears are enclosed in the pump chamber by the head. The stationary pin is accommodated within the driven gear and the drive shaft is coupled to the drive gear. The head is provided in the form of a flat plate with a plurality of holes for accommodating fasteners that couple the head to the distal end of the casing. | 2012-10-11 |
20120258007 | TWO-PIECE TWIST LOCK PISTON - A piston includes a crown portion generally defining an axis and having a skirt connecting portion. The skirt connecting portion is defined, at least in part, by a first crown mating portion, a second crown mating portion positioned radially from the first crown mating portion, and a crown chamber surface extending between the first crown mating portion and the second crown mating portion. The piston also includes a skirt having a crown connecting portion. The crown connecting portion is defined, at least in part, by a first skirt mating portion, a second skirt mating portion, and a skirt chamber surface extending between the first skirt mating portion and the second skirt mating portion. The first crown mating portion is selectively coupled to the first skirt mating portion. The second crown mating portion may be selectively coupled to the second skirt mating portion to define a piston chamber. | 2012-10-11 |
20120258008 | METHOD OF CONTROLLING THE CARBON OR OXYGEN CONTENT OF A POWDER INJECTION - The present invention relates to a method for controlling the carbon and/or oxygen content in a material by
| 2012-10-11 |
20120258009 | CONDITIONING A SURFACE OF AN ALUMINIUM STRIP - A method of conditioning the surface of a work piece, particularly of a strip or sheet, more particularly of a lithostrip or lithosheet, including an aluminum alloy is provided. The method for conditioning the surface of a work piece and a work piece including an aluminum alloy enabling an increasing manufacturing speed in electro-chemically graining and maintaining at the same time a high quality of the grained surface, includes a conditioning method which comprises at least the two steps, degreasing the surface of the work piece with a degreasing medium and subsequently cleaning the surface of the work piece by pickling. | 2012-10-11 |
20120258010 | COPPER ALUMINUM ALLOY MOLDED PART HAVING HIGH MECHANICAL STRENGTH AND HOT CREEP RESISTANCE - The subject of the invention is a cast part with high static mechanical strength, and high hot creep strength, made of aluminum alloy of chemical composition: | 2012-10-11 |
20120258011 | SELECTIVE CYTOPHERESIS DEVICES AND RELATED METHODS THEREOF - The present invention relates to systems and devices to treat and/or prevent inflammatory conditions within a subject and to related methods. More particularly, the invention relates to systems, devices, and related methods that sequester leukocytes and/or platelets and then inhibit their inflammatory action. | 2012-10-11 |
20120258012 | AUTOMATIC ANALYZER - An automatic analyzer according to the present invention is compact, mounting great number of reagents, having high processing ability. Reagent disks are arranged at inside and outside of a reaction disk. A reagent probe can inject a reagent into the position which is common position of both reagent disks. One of plural reagent probes approaches to one of reagent disks at one cycle. Plural reagent probes alternatively approach to the reagent disk. Therefore, the first reagents and the second reagents can be placed on both reagent disks. The mounting number of reagents can be increased without enlarging an analyzer. The cycle time can be shortened to make an automatic analyzer to have high processing ability. | 2012-10-11 |
20120258013 | CATALYST FOR LIFE SUPPORT SYSTEM - A catalyst for a life support system includes a plurality of titania support particles that define an average particle surface area. Platinum metal is disposed on the plurality of titania support particles such that a ratio of the average particle surface area to the percentage amount of the platinum metal is between 5 and 50 m | 2012-10-11 |
20120258014 | Contaminate Control Device - A contaminate control device for filtering contaminates from a gas such as air is provided. The device includes a housing having a first inlet and a first outlet. An axial flow filter is fluidly coupled between the first inlet and the first outlet, the axial flow filter has a second inlet and a second outlet. A second filter disposed about the axial flow filter and is fluidly coupled between the first inlet and the first outlet, the second filter having a third inlet on an inner diameter and a third outlet disposed on an outer diameter. A flow restrictor is fluidly coupled between the second inlet and the first inlet. | 2012-10-11 |
20120258015 | EXHAUST TREATMENT SYSTEM FOR AN INTERNAL COMBUSTION ENGINE - An exhaust system for an engine comprises a selective catalytic reduction (“SCR”) device having a NO | 2012-10-11 |
20120258016 | IGNITION OR PLASMA GENERATION APPARATUS - There is provided an ignition or plasma generation apparatus that eliminates the need for resonance means in a combustion chamber and simplifies the electrode structure within the combustion chamber in an instance where energy from each of a spark discharge and microwaves is used to ignite an air-fuel mixture gas in an internal combustion engine. The ignition or plasma generation apparatus includes a mixing circuit for mixing a high-voltage pulse from a high-voltage pulse generator and microwave energy from a microwave generator; and an ignition plug into which an output from the mixing circuit is supplied, the plug used for introducing the output into a combustion chamber of an internal combustion engine. The output supplied from the mixing circuit to the ignition plug is supplied in a manner in which the microwave energy and the high-voltage pulse are superimposed on each other on a same transmission line. | 2012-10-11 |
20120258017 | SYSTEM AND PROCESS FOR PRODUCTION OF FATTY ACIDS AND WAX ALTERNATIVES FROM TRIGLYCERIDES - A system for stripping fatty acids from triglycerides, the system including a reactor; a heating apparatus whereby a contents of the reactor may be heated to a temperature in the range of from 200° C. to 600° C.; and a vacuum pump capable of pulling a vacuum in the range of from 1 kPa to 50 kPa on the reactor. | 2012-10-11 |
20120258018 | SUBSTRATE PROCESSING APPARATUS, AND TRANSPORT DEVICE - There is provided a substrate procession apparatus, comprising: a processing chamber configured to house a plurality of substrates with a laminated film formed thereon which is composed of any one of copper-indium, copper-gallium, or copper-indium-gallium; a reaction tube formed so as to constitute the processing chamber; a gas supply tube configured to introduce elemental selenium-containing gas or elemental sulfur-containing gas to the processing chamber; an exhaust tube configured to exhaust an atmosphere in the processing chamber; heating section provided so as to surround the reaction tube; and a fan configured to forcibly circulate the atmosphere in the processing chamber in a short-side direction of the plurality of glass substrates, on surfaces of the plurality of glass substrates. | 2012-10-11 |
20120258019 | APPARATUS FOR A PROCESS FOR REDISSOCIATING MICHAEL ADDUCTS WHICH ARE PRESENT IN A LIQUID F AND HAVE BEEN FORMED IN THE PREPARATION OF ACRYLIC ACID OR ESTERS THEREOF - A redissociating apparatus to carry out a process for redissociating Michael adducts which are present in a liquid F with a proportion by weight of ≧10% by weight and have been formed in the preparation of acrylic acid or esters thereof is provided. The apparatus comprises a pump P, a separating column K with separating internals and a circulation heat exchanger UW, wherein, for the purpose of supplying the cleavage energy, the pump P sucks in bottoms liquid from the bottom space of the separating column K and, via the circulation heat exchanger UW, continually recycles it into the bottom space above the level of the bottoms liquid, and wherein the pump P is a radial circulation pump with an open impeller. | 2012-10-11 |
20120258020 | MICRO CHANNEL REACTOR WITH INTEGRAL HEATING ELEMENTS - In one example disclosed in the current application, by supplying just enough heat to the channel walls to replace the reaction heat removed during the reaction, a reactor exhibits tighter temperature tolerances with respect to the desired reaction temperature. In other words, the surface temperature can be more closely matched to the desired reaction temperature. Also, having a design where the channels can be scaled in both geometry and number allows control of the rate of mass transport through the channels to minimize unwanted side reactions. | 2012-10-11 |
20120258021 | METHOD AND APPARATUS FOR A COMBINATION MOVING BED THERMAL TREATMENT REACTOR AND MOVING BED FILTER - A moving bed gasification/thermal treatment reactor includes a geometry in which moving bed reactor particles serve as both a moving bed filter and a heat carrier to provide thermal energy for thermal treatment reactions, such that the moving bed filter and the heat carrier are one and the same to remove solid particulates or droplets generated by thermal treatment processes or injected into the moving bed filter from other sources. | 2012-10-11 |
20120258022 | Helium Barrier Atom Chamber - The present invention discloses a vacuum chamber having operating pressures in the ultra-high vacuum (UHV) range (10 | 2012-10-11 |
20120258023 | FLASH VAPOR GENERATOR AND ASSEMBLY COMPRISING A FLASH VAPOR GENERATOR - The invention relates to a device for generating decontamination agent vapor, in particular hydrogen peroxide vapor, comprising an evaporator body ( | 2012-10-11 |
20120258024 | CHEMICAL EXPOSURE INDICATION DEVICE - A chemical exposure indication device is disclosed. The device is removably attachable to a structure and includes a substrate having a first surface and a second surface and an indicating layer overlying the first substrate surface. The indicating layer includes a coating material that is chemically reactive with a pre-determined chemical compound that is known to degrade the structure. When the coating material is exposed to that corrosive compound in a pre-determined level associated with degradation of a metallic structure, the coating material provides a visual indication of the presence of the corrosive compound. | 2012-10-11 |
20120258025 | MICROFABRICATED DEVICES WITH COATED OR MODIFIED SURFACE AND METHOD OF MAKING SAME - A microfabricated device or component thereof, such as microfluidics or nanofluidics device having a uniform non-wetting or non-absorbing polymeric coating or surface modification formed on a surface thereof by ionisation or activation technology such as plasma processing, to produce a surface energy of less than 15 mNm | 2012-10-11 |
20120258026 | PIPETTING DEVICE - The invention relates to a sealing assembly for a metering device, in particular a multi-channel metering device. The sealing assembly serves to seal pipette tips with respect to the metering device. A multi-channel metering device comprises a multiplicity of openings arranged in one plane. A sealing plate with holes in the grid of the openings abuts this plane. Each pipette tip is provided with an annular collar which has an abutting face and is pressed against the sealing plate by force closure so as to enclose one hole. | 2012-10-11 |
20120258027 | Histology Slide and Paraffin Block Protector and Transport Sleeve - A protective sheath for prolonged storage of pathology paraffin blocks. The sheath protects the paraffin block against gouging, scratching, denting, rodents, and insects. A pathology slide slides into slots in the protective sheath fixing the slide into position in protective sheath. Fixation points are built on the side of the slide to allow a user or automated system to place and retrieve protective sheath. | 2012-10-11 |
20120258028 | TEST TUBE SUPPORT APPARATUS - A support stand for test tubes and more particularly to an easy to manufacture and economical test tube stand which facilitates handling of test tubes and samples contained therein in a field environment, particularly in a rugged field environment where the test tubes and samples are subject to significant movement and instability for example on a boat or truck during procurement and initial analysis of the sample. | 2012-10-11 |
20120258029 | FLUIDIZED BED AND METHOD AND SYSTEM FOR GAS COMPONENT CAPTURE - The present disclosure is directed to a process that allows dry sorbents to remove a target constituent, such as carbon dioxide (CO | 2012-10-11 |
20120258030 | GAS SEPARATION AND RECOVERY APPARATUS AND GAS SEPARATION AND RECOVERY METHOD - A gas separation and recovery apparatus that separates and recovers nitrogen oxides from a gas mixture includes: a liquid storing portion that stores a liquid, the liquid absorbing the nitrogen oxides; a gas-liquid contacting portion in which the liquid and the gas mixture contact with each other; and a liquid recovering portion that recovers the liquid after the liquid contacts the gas mixture. The liquid is an ionic liquid that chemically absorbs the nitrogen oxides. | 2012-10-11 |
20120258031 | CARBON DIOXIDE CAPTURE SYSTEM - A chilled ammonia capture system for capturing carbon dioxide from a flue gas stream comprises a first absorber and a second absorber. The first absorber operates at a temperature of about 25 to about 50 degrees Celsius. The operating temperature permits the use of a lower circulation rate, which leads to smaller diameter vessels and to fewer recirculation pumps, which in turn leads to lower operating and maintenance costs. | 2012-10-11 |
20120258032 | CATALYZED FILTER FOR TREATING EXHAUST GAS - Provided is a wall-flow filter coated with an SCR catalyst composition, wherein the catalyst composition contains transition metal promoted molecular sieve crystals, and wherein (i) the crystals have a mean crystalline size of about 0.5 μm to about 15 μm, (ii) the crystals are present in said composition as individual crystals, agglomerations having a mean particle size of less than about 15 μm, or a combination of said individual crystals and said agglomerations; and (iii) said molecular sieve is an aluminosilicate or a silico-aluminophosphate of a Framework Type having a maximum ring size of eight tetrahedral atoms. | 2012-10-11 |
20120258033 | METHOD FOR SYNTHESIZING AMMONIA - To provide a sustainable method for the synthesis of ammonia from nitrogen by low resources and low energy. | 2012-10-11 |
20120258034 | METHOD FOR GENERATING NITRIC OXIDE - The invention relates to a method for generating nitric oxide, in particular for therapeutic applications, which comprises the steps of: guiding a process gas into a reaction chamber | 2012-10-11 |
20120258035 | POLYCRYSTALLINE DIAMOND AND METHOD OF MANUFACTURING THE SAME - Polycrystalline diamond includes cubic diamond and hexagonal diamond, and a ratio of X-ray diffraction peak intensity of a (100) plane of the hexagonal diamond to X-ray diffraction peak intensity for a (111) plane of cubic diamond is not lower than 0.01%. In addition, a present method of manufacturing polycrystalline diamond includes the steps of preparing a non-diamond carbon material having a degree of graphitization not higher than 0.58 and directly converting the non-diamond carbon material to cubic diamond and hexagonal diamond and sintering the non-diamond carbon material, without adding any of a sintering agent and a binder, under pressure and temperature conditions at which diamond is thermodynamically stable. | 2012-10-11 |
20120258036 | METHOD FOR PREPARING BARIUM TITANATE - Provided is a method for preparing barium titanate, which comprises: dissolving BaCl | 2012-10-11 |
20120258037 | METAL SUPPORTED SILICA BASED CATALYTIC MEMBRANE REACTOR ASSEMBLY - A catalytic membrane reactor assembly for producing a hydrogen stream from a feed stream having liquid hydrocarbons, steam, and an oxygen source through the use of an autothermal reforming reaction, a water-gas-shift reaction, and a hydrogen permeable membrane. | 2012-10-11 |
20120258038 | USES OF APOPTOTIC CELL-TARGETING PEPTIDES, LABEL SUBSTANCES AND LIPOSOMES CONTAINING A THERAPEUTIC AGENT FOR PREVENTING, TREATING OR THERAPEUTICALLY DIAGNOSING APOPTOSIS-RELATED DISEASES - The present invention relates to a composition for preventing, treating or theranosis of apoptosis-related diseases comprising liposome comprising apoptotic cell-targeting peptides, label substances and a therapeutic agent. The present invention may be used for drug delivery to the apoptotic cells in cancer or tumor mass, the apoptotic myocardial cells in myocardial infarction lesion, the apoptotic stroke cells in stroke lesion, the apoptotic cells in arteriosclerosis lesion and further may be used for detection of the cells and imaging diagnosis. Therefore, it can be used for theranosis as well as preventing or treating the diseases. | 2012-10-11 |
20120258039 | TREATMENT OF TUMORS USING SPECIFIC ANTI-L1 ANTIBODY - The present invention relates to the anti-L1 monoclonal antibody 9.3 as well as to related antibodies or binding molecules and well as to the uses thereof, especially in tumor treatment. | 2012-10-11 |
20120258040 | COMPOSITIONS AND METHODS OF MONOCLONAL AND POLYCLONAL ANTIBODIES SPECIFIC FOR T CELL SUBPOPULATIONS - The invention provides compounds and methods for the ex vivo or in vivo expansion of NK T cells, CD1d-reactive T cells, and JαQ | 2012-10-11 |
20120258041 | COMPOSITIONS AND METHODS FOR TREATING DISEASES OF PROTEIN AGGREGATION INVOLVING IC3B DEPOSITION - The invention provides antibodies that preferentially bind to iC3b relative to C3b. These antibodies serve to reduce the toxicity of this fragment and find use in treatment and prophylaxis of a variety of diseases associated with deposits of the fragment. | 2012-10-11 |
20120258042 | COMBINED USE OF TGF-B SIGNALING INHIBITOR AND ANTITUMOR AGENT - The combined use of a TGF-β signaling inhibitor and an antitumor active substance or an imaging agent modified by a drug-encapsulating macromolecular micelle, or the like, is provided. The selective delivery capability of the antitumor active substance or the imaging agent to the target is improved, increasing the antitumoral activity in the target. | 2012-10-11 |
20120258043 | Linkable Lewis X Analogs - Disclosed herein is a class of linkable tetrasaccharide compounds that includes the amino phenyl glycoside of sialyl Lewis X (SLe | 2012-10-11 |
20120258044 | LIPID-BASED NANOPARTICLES - Lipid-based nanoparticle compositions are provided. The compositions generally comprise lipid-hydrophilic polymer-amyloid binding ligand conjugates, and may be liposomal compositions. The compositions, including the liposomal compositions, may be useful for imaging and/or the treatment of amyloid-β plaque deposits characteristic of Alzheimer's Disease. | 2012-10-11 |
20120258045 | INHIBITORS AND METHODS OF TREATMENT OF CARDIOVASCULAR DISEASES, AND METHODS FOR IDENTIFYING INHIBITORS - The present invention provides, inter alia, inhibitors of cardiovascular diseases and disorders. The present invention also provides therapeutic methods for preventing and/or treating cardiovascular diseases and disorders. Further, the present invention provides methods of identifying inhibitors of cardiovascular diseases and disorders as well as model systems suitable for identifying such inhibitors as well as methods and compositions for detecting and/or diagnosing cardiovascular diseases and disorders. | 2012-10-11 |
20120258046 | MANNOSE-CONTAINING SOLUTION FOR LYOPHILIZATION, TRANSFECTION AND/OR INJECTION OF NUCLEIC ACIDS - The present invention is directed to (the use of) a solution containing at least one nucleic acid (sequence) and free mannose for lyophilization, transfection and/or injection, particularly of RNA and mRNA. The inventive solution exhibits a positive effect on stabilization of the nucleic acid (sequence) during lyophilization and storage but also leads to a considerable increase of the transfection efficiency of a nucleic acid. It thus also increases in vivo expression of a protein encoded by such a nucleic acid upon increased transfection rate. The present invention is furthermore directed to a method of lyophilization using the mannose-containing solution, to pharmaceutical compositions, vaccines, kits, first and second medical uses applying such a mannose-containing solution and/or a nucleic acid (sequence) lyophilized or resuspended with such a solution. | 2012-10-11 |
20120258047 | EPSILON-POLY-LYSINE CAPSULES - The present disclosure relates to capsules having a core and one or more capsular walls surrounding the core, wherein at least one of the capsular walls comprises a polymer comprising epsilon-poly-lysine or a derivative thereof. | 2012-10-11 |
20120258048 | OPTICAL FLUORESCENT IMAGING - Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared (NIR) spectral range. The NIR is highly sensitive for tumor detection and tracking. The application discloses targeting a tumor-enriched cell surface receptor with a ligand-conjugated fluorescent probe, which specifically allows detection of the tumor relative to the negligible animal autofluorescence. | 2012-10-11 |
20120258049 | POLYMALIC ACID BASED NANOCONJUGATES FOR IMAGING - Nanoconjugates that include a polymalic-based molecular scaffold with one or more imaging moiety and one or more targeting modules attached to the scaffold are provided. Methods of targeting a diseased cell or a diseased tissue in a subject by administering the nanoconjugate are described. Methods of synthesizing the nanoconjugate are also provided. | 2012-10-11 |
20120258050 | 13C-MR DETECTION USING HYPERPOLARISED 13C-FRUCTOSE - The invention relates to a method of | 2012-10-11 |
20120258051 | Multistrata nanoparticles and methods for making multistrata nanoparticles - A composition comprising a core comprising an iron oxide, a first shell comprising at least one plasmon active metal at least partially surrounding the core, a second shell comprising a dielectric material at least partially surrounding the first shell, and a third shell comprising at least one plasmon active metal at least partially surrounding the second shell. | 2012-10-11 |
20120258052 | AEROSOL COMPRISING A STARCH COMPOUND AND A (C8 TO C20) MONOCARBOXYLIC ACID COMPOUND - Cosmetic products for treating keratin fibers, especially human hair, containing, in a cosmetic carrier, at least one starch compound, at least 0.01% by weight of a (C | 2012-10-11 |
20120258053 | ORAL CARE COMPOSITIONS FOR USE WITH AN ORAL LIGHT DEVICE - Generally regarded as safe (GRAS) dyes can be used as photosensitizing dyes in oral compositions to provide anti-bacterial and anti-inflammatory efficacy. Embodiments include oral care compositions including photosensitizing dyes, methods of making the compositions, methods of using the compositions, and kits containing the compositions and light emitting devices. | 2012-10-11 |
20120258054 | Oral hygiene method and formula - The present invention generally relates to oral compositions such as toothpastes, toothpowders, liquid dentrifices, mouthwashes, rinses, dental floss, denture cleansers, chewing gums, lozenges and the like. In particular, it relates to such oral compositions that include cesium and rubidium salts. In one aspect of the present invention, a composition for oral use is provided. The composition includes a cesium or rubidium salt and water having a surface tension ranging between 45 and 70 dynes per cm | 2012-10-11 |
20120258055 | MINERAL SUNSCREEN COMPOSITION AND PROCESS FOR PROTECTING SKIN FROM PHOTODAMAGE AND AGING - The present invention is directed to a composition and method for protecting a keratinous substrate from harmful UV rays by applying onto the substrate a composition containing: (a) at least one oil phase thickening agent chosen from an activated clay; (b) at least one substantially solid form dispersing aid; (c) at least one non-volatile solvent; (d) at least one inorganic sunscreen active; (e) at least one emulsifier; (f) at least one volatile solvent; and (g) water, and wherein (a) and (b) are present in the composition in a ratio by weight ranging from greater than 1:4 to less than 1:10. | 2012-10-11 |
20120258056 | TREATMENT OF CANCER AND COMPOSITIONS - The invention discloses a method of identifying a gene associated with stage III primary cancer or lymph node metastasis. The genes so identified include CAV1, CST3, LIMK1, MMP2, MMP15, VEGF, ETV4, MMP9, PIK3C2B, and SERPIN1. Also disclosed are methods for diagnosis, prognosis, and treatment of cancer. The invention further discloses compositions for preventing and treating diseases. | 2012-10-11 |
20120258057 | SILICONE ORGANIC ELASTOMER GELS FROM ORGANOPOLYSILOXANE RESINS - Gel compositions are disclosed comprising a silicone elastomer from the reaction of an SiH containing organopolysiloxane resin and an organic compound having at least two aliphatic unsaturated groups in its molecule. | 2012-10-11 |
20120258058 | FORMULATION WITH IRRITATION REDUCING ACTION COMPRISING BISABOLOL AND [6]-PARADOL - The present invention relates to formulations having an irritation-reducing action, corresponding cosmetic and pharmaceutical products as well as associated methods and uses thereof. | 2012-10-11 |
20120258059 | COSMETIC, EXTERNAL SKIN PREPARATION, AND MEDICAL INSTRUMENT - It is an object of the present invention to provide a cosmetic or external skin preparation that has an improved feel in use, e.g., excellent stretching on the skin surface, excellent permeation into the skin, and no stickiness, or crinkles. A cosmetic or an external skin preparation, and a medical instrument, comprising at least one lipid peptide-based gelator that contains a low-molecular lipid peptide of Formula (1): | 2012-10-11 |
20120258060 | METHODS FOR PROTECTING THE SKIN FROM RADIATION INSULTS - The present invention relates to methods and compositions for the protection of skin and mucous membranes from undesirable side effects of ionizing radiation in a patient undergoing ionizing radiation therapy. In particular, the application describes compositions and methods comprising the topical use of Nrf2 inducers. | 2012-10-11 |
20120258061 | Method for Treating Skin with Retinoids and Retinoid Boosters - A skin care product comprising from about 0.001% to about 10% of a retinoid in combination with 0.0001% to about 50% of at combination of retinoid hoosters. | 2012-10-11 |
20120258062 | TOPICAL APPLICATION OF IVERMECTIN FOR THE TREATMENT OF DERMATOLOGICAL CONDITIONS/AFFLICTIONS - Dermatological conditions/afflictions such as rosacea, common acne, seborrheic dermatitis, perioral dermatitis, acneform rashes, transient acantholytic dermatosis, and acne necrotica miliaris, most notably rosacea, are treated by topically applying onto the affected skin area of an individual in need of such treatment, a topical pharmaceutical composition which comprises a thus effective amount of ivermectin. | 2012-10-11 |
20120258063 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION - An object is to provide an external preparation for skin preferably usable to prevent or ameliorate pigmentation. The object is achieved by providing a preventing or ameliorating agent for pigmentation, consisting of a compound represented by the following general formula (1), an isomer thereof, and/or a pharmacologically acceptable salt thereof, and an external preparation for skin containing the same as a component: | 2012-10-11 |
20120258064 | SUBSTANTIALLY ANHYDROUS COMPOSITIONS FOR PERSONAL CARE - Moisturizers are mixtures of chemicals specifically designed to make the external layers of the skin (epidermis) softer and more pliable, by increasing its hydration (water) content and reducing evaporation. Loss of moisture in the stratum corneum causes dry skin and compromises its barrier function. Therefore, maintaining the hydration level of this layer is essential for healthy skin. For individuals who wash hands frequently or have dry skin (e.g. due to age or diabetes) using a moisturizer may be important. The personal care composition described herein provides a moisturizing system that does not have a negative effect on skin such as that which can be attributed to surfactants. | 2012-10-11 |
20120258065 | USE OF 2,3-DIHYDROXYPROPYL DODECANOATE FOR TREATING SEBORRHOEA - The present invention relates to the use of 2,3-dihydroxypropyl dodecanoate for treating seborrhea. | 2012-10-11 |
20120258066 | ACRYLIC POLYMER - The present invention relates to acrylic emulsion polymers having excellent hair styling properties as well as their use in hair care preparations in particular hair styling preparations. | 2012-10-11 |
20120258067 | Hair Conditioning Composition Having Higher Yield Point and Higher Conversion Rate of Fatty Compound to Gel Matrix - Disclosed is a hair conditioning composition comprising: (a) a cationic surfactant; (b) a high melting point fatty compound; and (c) an aqueous carrier; wherein the cationic surfactant, the high melting point fatty compound, and the aqueous carrier form a gel matrix; wherein the composition has from about 90% to about 100% of a conversion rate of the high melting point fatty compound to the gel matrix; and wherein the composition has a yield point of about 33Pa or more. Also disclosed is a method of manufacturing of hair conditioning composition. The compositions of the present invention, and the compositions made by the method of the present invention, provide improved conditioning benefits, especially, improved wet conditioning benefits after rinsing and improved dry conditioning, while maintaining wet conditioning benefit before rinsing. | 2012-10-11 |
20120258068 | SCAFFOLDS FORMED FROM POLYMER-PROTEIN CONJUGATES, METHODS OF GENERATING SAME AND USES THEREOF - Conjugates are provided herein which comprise a protein attached to at least two polymeric moieties, at least one of which exhibits reverse thermal gelation. The conjugates are suitable for being cross-linked by non-covalent and/or covalent cross-linking. Compositions-of-matter comprising cross-linked conjugates are provided herein, as well as processes for producing same. Methods of controlling a physical property of compositions-of-matter are also provided herein. The conjugates and compositions-of-matter may be used for various applications, such as cell growth, tissue formation, and treatment of disorders characterized by tissue damage or loss, as described herein. | 2012-10-11 |
20120258069 | RGD-BINDING COMPOUNDS AND METHODS OF USE - Provided herein are compositions and methods for preventing and treating diseases and risk factors associated with metabolic syndrome by targeting the RGD-binding site of selected intra- and extracellular proteins. Exemplary compositions include RGD-polyphenol conjugates via an ester linkage; polyphenol polymer conjugated to RGD analogs or mimetics; and RGD polymer conjugates linked to polyphenol. | 2012-10-11 |
20120258070 | Methods and Compositions for Promoting Organ Development - Compositions and methods are provided for promoting organ development in warm blooded animals, and in particular in certain aspects a premature infant or fetus. Compositions and methods are also provided for the administration of at least one colony stimulating factor-1 protein (CSF-1), precursor, variant, analogue, derivative thereof, or combinations thereof, or otherwise, at least one nucleic acid molecule encoding colony stimulating factor-1 protein (CSF-1), precursor, variant, analogue, derivative thereof, or combinations thereof. | 2012-10-11 |
20120258071 | Compositions and Methods of Use for MGD-CSF in Disease Treatment - Disclosed is a newly identified secreted molecule, identified herein as “monocyte, granulocyte, and dendritic cell colony stimulating factor” (MGD-CSF), the polypeptide sequence, and polynucleotides encoding the polypeptide sequence. Also provided is a procedure for producing the polypeptide by recombinant techniques employing, for example, vectors and host cells. Additionally, procedures are described to modify the disclosed novel molecules of the invention to prepare fusion molecules. Also disclosed are methods for using the polypeptides and active fragments thereof for treatment of a variety of diseases, including, for example, cancer, autoimmune and inflammatory diseases, infectious diseases, and recurrent pregnancy loss. | 2012-10-11 |
20120258072 | Interleukin-11 Fusion Proteins - The invention relates to proteins comprising Interleukin 11 (IL-11) (including, but not limited to, fragments and variants thereof), which exhibit thrombopoietic or anti-inflammatory properties, fused to albumin (including, but not limited to, fragments or variants of albumin). These fusion proteins are herein collectively referred to as “albumin fusion proteins of the invention”. These fusion proteins exhibit extended shelf-life and/or pharmacokinetic properties and/or extended or therapeutic activity. The invention encompasses therapeutic albumin fusion proteins, compositions, pharmaceutical compositions, formulations and kits. The invention also encompasses nucleic acid molecules encoding the albumin fusion proteins of the invention, as well as vectors containing these nucleic acids, host cells transformed with these nucleic acids and vectors, and methods of making the albumin fusion proteins of invention using these nucleic acids, vectors, and/or host cells. The invention also relates to compositions and methods for treatment or prophylaxis of thrombocytopenia or inflammatory diseases. | 2012-10-11 |
20120258073 | IMMUNOTHERAPY - The present invention provides combinations of (a) an immunoconjugate comprising at least one antigen-binding moiety and an effector moiety, and (b) an antibody engineered to have increased effector function, for use in treating a disease in an individual in need thereof. Further provided are pharmaceutical compositions comprising the combinations, and methods of using them. | 2012-10-11 |
20120258074 | Systems, Models and Methods for Identifying and Evaluating Skin-Active Agents Effective for Treating Dandruff/Seborrheic Dermatitis - Methods and systems for determining functional relationships between a skin-active agent and a skin condition of interest, and methods and systems for identifying cosmetic agents effective for treatment of dandruff, as well as the use of agents identified by such methods and systems for the preparation of cosmetic compositions, personal care products, or both are provided. Methods for developing in vitro models of skin disease and models for specific skin diseases are also provided. | 2012-10-11 |
20120258075 | Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists - The present invention provides methods for preventing, attenuating neuronal damage or stimulating neuronal repair prior or following central nervous system injury. | 2012-10-11 |
20120258076 | METHOD FOR CHARACTERIZING HOST IMMUNE FUNTION BY EX VIVO INDUCTION OF OFFENSIVE AND DEFENSIVE IMMUNE MARKERS - A host's immune function can be characterized by quantifying changes in offensive and defensive immune function associated markers. Certain methods can be used to identify a potentially efficacious therapy for a subject based on the induction of expression of offensive and defensive immune function-associated markers. Additionally, some methods can be used to identify drugs that allow the stimulation of either the offensive or defensive immune response while inhibiting the other of offensive or defensive immune response. | 2012-10-11 |
20120258077 | Human M2e Peptide Immunogens - The present invention provides novel peptide immunogens comprising influenza virus matrix 2 protein epitopes and related compositions and methods. The present invention relates to a composition comprising a peptide immunogen useful for the prevention and treatment of an influenza virus-mediated disease. The invention also relates to vaccines, immunogenic products and immunogenic compositions containing the peptide immunogens. | 2012-10-11 |
20120258078 | ANTIVIRAL COMPOUNDS OF THREE LINKED ARYL MOIETIES TO TREAT DISEASES SUCH AS HEPATITIS C - The present invention relates to novel Linked Tricyclic Aryl Compounds, compositions comprising at least one Linked Tricyclic Compound, and methods of using Linked Tricyclic Aryl Compounds for treating or preventing HCV infection in a patient. in one aspect, the present invention provides Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein: Non-limiting examples of the Compounds of Formula (II) include compound 56 | 2012-10-11 |
20120258079 | Treatment and Prevention of Dengue Virus Infections - Methods and pharmaceutical compositions for treating viral infections, by administering certain | 2012-10-11 |
20120258080 | PYRIDOPYRAZINE DERIVATIVES AND THEIR USE - The present invention provides new pyridopyrazine compounds which are suitable for the treatment or prevention of physiological and/or pathophysiological states mediated and/or modulated by signal transduction pathways and/or enzymes in mammals and in particular in humans. | 2012-10-11 |
20120258081 | METHODS OF TREATING PROLIFERATIVE DISEASES - Provided herein are methods of administering N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, or a pharmaceutically acceptable salt or solvate thereof, to human patients, including a specific patient population. Specifically, dosing, dosing schedules or dosing regimens are provided herein. Methods of treating proliferative diseases or FLT-3 mediated diseases in humans are also provided. | 2012-10-11 |
20120258082 | PRODUCTION OF IFN-LAMBDA BY CONVENTIONAL DENDRITIC CELLS AND USES THEREOF - In the present invention, CD8+ conventional dendritic cells (CD8+ cDCs) and equivalents thereof (eCD8+ cDCs) in mouse and human have been established as major source of IFN-lambda (IFN-λ) in response to double-stranded (ds) nucleic acids. The invention relates to therapeutic applications of ds nucleic acids or analogs thereof targeting CD8+ and/or eCD8+ cDCs in the prevention and/or treatment of infectious diseases, preferably viral infections, or cancer. Furthermore, the invention relates to an in vitro method for producing IFN-λ and/or generating or obtaining a population of IFN-λ producing CD8+ or eCD8+ cDCs as well as in vitro method for detecting or screening for CD8+ and/or eCD8+ cDCs. In addition, the invention relates to a Flt3-ligand or a M-CSF receptor ligand for use in increasing the level of CD8+ and/or eCD8+ cDCs in a subject suffering from an infectious disease or cancer. | 2012-10-11 |
20120258083 | PLACENTAL VASCULAR LOBULE STEM CELLS - The present invention provides isolated populations of stem and progenitor cells from fetal vascular lobules of the placenta. The isolated populations of stem and progenitor cells of the invention express the markers CD144, CD105, and/or CD31 and lack expression of the hematopoietic-lineage marker CD45. Under specific conditions, cells of the invention may function as endothelial precursors and may provide therapeutic preparations, for example, in the treatment of ischemia. | 2012-10-11 |
20120258084 | PROGENITOR CELLS AND USES THEREOF - Methods for preparing progenitor cells are described where epithelial cells are induced to undergo epithelial-mesenchymal transition as a result of exposure to an inducing agent or introduction of a gene therein that induces epithelial-mesenchymal transition. Progenitor cells resulting therefrom have use in cell-based therapies, among other utilities. | 2012-10-11 |
20120258085 | Expansion of NK Cells - A method of large scale expansion and simultaneous activation of NK cells and NK-like T cells in a closed cell culture system is presented, wherein the expanded cells exhibit increased cytotoxicity. | 2012-10-11 |
20120258086 | PLATELET SOLUTION FOR USE IN JOINT SURGERY - The invention is directed to a method of accelerating healing in a joint comprising administering a platelet composition to the joint. | 2012-10-11 |
20120258087 | ISOTONIC BEVERAGE WITH CHELATES - The subject of the invention is an isotonic beverage with chelates containing carbohydrates, mineral amino acid chelates, L-carnitine, sweeteners, flavouring substances, and a diluent, the essential feature of the beverage being the content of up to 0.1 wt % of mineral components in the form of mineral amino acid chelates, preferably bisglycinates and glycinates, from 0.1 to 50 wt % of isomaltulose, up to 15 wt % of L-carnitine and/or its derivatives, from 5 to 84% of carbohydrates, up to 50 wt % of bioactive substances, up to 50 wt % of flavouring substances, up to 80 wt % of polyalcohols, diluents, tableting aids, stabilizers, antioxidants, dyes, and 0.013-25 wt % of sweeteners, whereby its osmolarity is 275-295 mOsm/kg and pH is 2-5. | 2012-10-11 |
20120258088 | CHIMERIC BACTERIOPHAGE LYSIN WITH ACTIVITY AGAINST STAPHYLOCOCCI BACTERIA - The present disclosure relates to chimeric bacteriophage lysins useful for the identification and/or reduction of | 2012-10-11 |
20120258089 | SOLUBLE BETA-N-ACETYLGLUCOSAMINIDASE BASED ANTIBIOFILM COMPOSITIONS AND USES THEREOF - The present invention provides compositions comprising an antibiofilm enzyme, a soluble β-N-acetylglucosaminidase similar to the dspB gene (DispersinB®), and an antimicrobial for preventing growth and proliferation of biofilm-embedded microorganisms in acute and chronic wounds, and methods of treatment. The invention further provides methods for preparing medical devices, and in particular, wound care devices using soluble β-N-acetylglucosaminidase based antimicrobial compositions. | 2012-10-11 |
20120258090 | METHOD FOR PRODUCTION OF RECOMBINANT HUMAN THROMBIN - The present invention relates to a method is provided for producing recombinant human thrombin from recombinant prothrombin using recombinant ecarin having the sequence SEQ ID NO 2 or a homologue thereof. | 2012-10-11 |
20120258091 | GENETIC PRODUCTS DIFFERENTIALLY EXPRESSED IN TUMORS AND THE USE THEREOF - The invention relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for the expressed products. An embodiment of the invention also relates to the therapy and diagnosis of disease in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors, and to the nucleic acids coding for the polypeptides, peptides and proteins. | 2012-10-11 |
20120258092 | Optimized Fc Variants - The present invention relates to optimized CD20 antibodies having Fc variants, methods for their generation, and method for their application, such as methods of enhancing macrophage activation, particularly for therapeutic purposes. | 2012-10-11 |
20120258093 | VLA-4 AS A BIOMARKER FOR PROGNOSIS AND TARGET FOR THERAPY IN DUCHENNE MUSCULAR DYSTROPHY - The invention relates to methods for the treatment of Duchenne muscular dystrophy and to methods for determining the prognosis of a subject affected with Duchenne Muscular Dystrophy. More particularly, the present invention relates to a VLA-4 antagonist for use in the treatment of Duchenne Muscular Dystrophy. The present invention also relates to a method for determining the prognosis of a subject affected with Duchenne Muscular Dystrophy wherein said method comprising a step consisting of determining the level of VLA-4 high T cells in a blood sample obtained from said subject. | 2012-10-11 |
20120258094 | METHOD FOR TREATING A RHEUMATIC DISEASE USING A SOLUBLE CTLA4 MOLECULE - The present invention relates to compositions and methods for treating autoimmune diseases, such as diabetes, by administering to a subject a CTLA4 molecule that block endogenous B7 molecules from binding their ligands. | 2012-10-11 |