| 39th week of 2008 patent applcation highlights part 42 |
| Patent application number | Title | Published |
|---|
| 20080233570 | METHODS FOR IDENTIFICATION OF SEPSIS-CAUSING BACTERIA - The present invention provides compositions, kits and methods for rapid identification and quantification of sepsis-causing bacteria by molecular mass and base composition analysis. | 2008-09-25 |
| 20080233571 | Method for identifying compounds which affect synaptogenesis - A method is provided for identifying a compound which affects the formation of AMPA receptors into aggregates. A method is also provided for identifying a compound which affects the formation of synaptic connections. A method is provided for identifying a compound that modulates immediate early gene expression. A method is further provided for increasing the number of excretory synapses of a neuron, including introducing into the neuron a polynucleotide sequence encoding a Narp operatively linked to a promoter, or a Narp polypeptide, thereby increasing the number of excretory synapses of the neuron. A method is provided for treating a subject with a disorder associated with a decrease in a function or expression of Narp, including administering to the subject a therapeutically effective amount of a compound that augments Narp function or expression. A method is provided for treating a subject with a disorder associated with an increase in a function or expression of Narp, including administering to the subject a therapeutically effective of a compound that inhibits Narp function or expression. A method is provided for treating a patient having or at risk of having a disorder associated with decreased Narp expression. The method includes introducing into a cell of a patient having a disorder associated with decreased Narp expression or function a polynucleotide sequence encoding a Narp polypeptide operatively linked to a promoter. A method is provided for treating a subject having a deficiency in a neuron's immediate early gene responsiveness to a stimulus. The method includes administering a nucleic acid encoding a Narp polypeptide to said subject, wherein the administration results in amelioration of the deficiency. | 2008-09-25 |
| 20080233572 | METHODS AND COMPOSITIONS FOR THE DETECTION AND QUANTIFICATION OF E.COLI AND ENTEROCOCCUS - The present invention is drawn to methods and compositions for the rapid assessment of fecal indicator bacteria in a sample. Provided herein are novel primer and probe compositions for use in detecting the presence of these organisms in a sample, particularly using quantitative PCR methods. Provided herein are novel oligonucleotide primers and probes, including the primers set forth in SEQ ID NO:1-4, the novel oligonucleotide probe sequences set forth in SEQ ID NO:5-8, and methods for using these primers and probes for the detection and/or quantification of fecal indicator bacteria, particularly | 2008-09-25 |
| 20080233573 | Gene expression profiling for identification, monitoring and treatment of transplant rejection - The present invention provides methods of characterizing organ transplant rejection or inflammatory conditions associated with organ transplant rejection using gene expression profiling. | 2008-09-25 |
| 20080233574 | Map-Based Genome Mining Method for Identifying Regulatory Loci Controlling the Level of Gene Transcripts and Products - The invention pertains to a method for identifying one or more regions within a genome of an organism of interest that mediate the expression of one or more genes of interest. The method comprises identifying a first and a second organism of interest, the first organism of interest is characterized by exhibiting a measurable response to an environmental stimulus, or otherwise, exhibiting a phenotype associated with differential gene expression associated with a process of interest. The second organism of interest is characterized by lacking or not exhibit as strong a response to the stimulus as that observed within the first organism of interest, or it exhibits a different phenotype compared with that of the first organism of interest, wherein the different phenotype is associated with the process of interest, or it exhibits a phenotype of interest that segregates when compared with the first organism of interest, or a combination thereof. The first and second organisms of interest are crossed to produce a population of segregated progeny and RNA is extracted from each of the segregated progeny. The level of gene expression for one or more genes of interest that are associated with the response to an environmental stimulus, or process of interest is quantified. A linkage map of the segregated progeny using one or more markers is prepared, and the relationship between said one or more markers on the linkage map and the gene expression of the one or more genes of interest is determined and one or more quantitative trait loci (QTL) identified. This method also pertains to identifying one or more QTLs associated with one or more genes of interest in segregated progeny that are subjected a desired environmental stimulus. Furthermore, this method may be used for the identification of one or more QTL corresponding to a transcription factor or any factor controlling the expression of one or more genes of interest, and the one or more genes located at the one or more QTL may be isolated and characterized. | 2008-09-25 |
| 20080233575 | Methods for increasing accuracy of nucleic scid sequencing - The invention provides methods for improving the fidelity of a sequencing-by-synthesis reaction by resequencing at least a portion of a nucleic acid template. | 2008-09-25 |
| 20080233576 | METHOD FOR FEATURE SELECTION IN A SUPPORT VECTOR MACHINE USING FEATURE RANKING - In a pre-processing step prior to training a learning machine, pre-processing includes reducing the quantity of features to be processed using feature selection methods selected from the group consisting of recursive feature elimination (RFE), minimizing the number of non-zero parameters of the system (l | 2008-09-25 |
| 20080233577 | METHOD FOR PRODUCING LIGANDS, LIGANDS AND TEST KIT - The invention relates to a method for producing ligands, in particular aptamers. With this method, a target substance is offered to a set of candidate ligands, and the unbonded ligands are separated out by a cross-flow filtration process. The retentate, which contains ligand-target substance complexes, then undergoes further continuous cross-flow filtration while chemical and/or physical parameters are being varied. After each variation of a parameter, those candidate ligands whose bond with the target substance was dissolved by the parameter variation are collected in separate fractions and separately multiplied. | 2008-09-25 |
| 20080233578 | METHOD FOR DETECTING MUTATION OF NUCLEIC ACID USING SINGLE-STRANDED DNA-BINDING PROTEIN - A method for judging the presence or absence of a mutation in a nucleic acid sequence, the method includes utilizing a single-stranded DNA-binding protein; the aforementioned method for judging the presence or absence of a mutation in a nucleic acid sequence, wherein the aforementioned presence or absence of a mutation in a nucleic acid sequence is judged by a product formed by a nucleic acid amplification reaction utilizing the single-stranded DNA-binding protein; and a kit for judging the presence or absence of the aforementioned mutation in a nucleic acid sequence. | 2008-09-25 |
| 20080233579 | PRIMER SET FOR DETECTING OVEREXPRESSION OF KATP CHANNEL AND KIT COMPRISING SAID PRIMER SET - The present invention relates to a primer set for confirming an increase of mRNA in an ATP-sensitive potassium channel (K | 2008-09-25 |
| 20080233580 | Transgenic animal model - The present invention is related to a transgenic, non-human animal, particularly a transgenic rodent, but especially a transgenic mouse model which allows for the simultaneous, tissue-specific and temporally-controlled regulation of transgene expression and can be used as a tool to investigate the consecutive steps involved in initiation and progression of certain diseases such as cancer, but particularly lung cancer. | 2008-09-25 |
| 20080233581 | HISTONE DEACETYLASE AND METHODS OF USE THEREOF - The present invention provides nucleic acid molecules that encode histone deacetylase, as well as recombinant vectors and host cells that include the subject nucleic acid molecules. Also provided are histone deacetylase polypeptide compositions. The histone deacteylase nucleic acid molecules are useful in a variety of diagnostic and therapeutic applications, which are also provided. | 2008-09-25 |
| 20080233582 | SINGLE NUCLEOTIDE POLYMORPHISMS ASSOCIATED WITH SUSCEPTIBILITY TO CARDIOVASCULAR DISEASE - The present invention provides SNPs, polymorphic variants, and haplotypes associated with cardiovascular disease. The invention also provides methods for detecting the SNPs, polymorphic variants, and haplotypes. The invention also provides methods for determining an individual's genotype with respect to one or more polymorphisms and/or haplotypes associated with cardiovascular disease. The invention further provides methods of determining whether an individual has or is susceptible to development or occurrence of a cardiovascular disease or event. The methods are useful for providing diagnostic and/or prognostic information, selecting therapeutic regimens, etc. The invention further provides reagents and kits for practicing the methods. | 2008-09-25 |
| 20080233583 | BIOMARKERS FOR PREECLAMPSIA - The present invention provides methods for predicting the development of and diagnosing preeclampsia, providing a prognosis, and predicting recurrence of the disease using molecular markers that are overexpressed or underexpressed in preeclampia. Also provided are methods to identify compounds that are useful for the treatment or prevention of preeclampsia. | 2008-09-25 |
| 20080233584 | RNAi MODULATION OF MLL-AF4 AND USES THEREOF - The invention relates to compositions and methods for modulating the expression of the MLL-AF4 fusion gene, and more particularly to the downregulation of MLL-AF4 by chemically modified oligonucleotides. | 2008-09-25 |
| 20080233585 | USE OF DIFFERENTIALLY EXPRESSED NUCLEIC ACID SEQUENCES AS BIOMARKERS FOR CANCER - The present invention relates to novel marker sequences that are differentially expressed in cancer cells or tissue of a subject with cancerous conditions. The present invention also relates to assays for diagnosis, prognosis, staging, monitoring, therapeutic treatment, and marker sequence related agents including probes, primers, antibodies, and therapeutic compositions. | 2008-09-25 |
| 20080233586 | METHODS FOR PREPARING AND PREFORMING ANALYSIS - The invention relates to methods for preparing and performing quantitative PCR analyses, a new sealing device and a new use. According to the invention, a sample vessel containing the samples to be analyzed is sealed by placing a planar sealing device on the vessel to cover the samples and applying pressure on the sealing device in order to deform the sealing device so as to form a light-refracting geometry individually for the samples to be analyzed. The invention offers a convenient way of sealing the vessel and forming analysis-improving optical lenses over the samples simultaneously. | 2008-09-25 |
| 20080233587 | METHOD FOR DIRECT AMPLIFICATION FROM CRUDE NUCLEIC ACID SAMPLES - The present teachings relate to improved methods, kits, and reaction mixtures for amplifying nucleic acids. In some embodiments a novel direct buffer formulation is provided which allows for the direct amplification of the nucleic acids in a crude sample with minimal sample purification. | 2008-09-25 |
| 20080233588 | Analytical Method and Kit - Analytical methods using RNA-containing probes for the detection or analysis of nucleic acid sequences is described. These probes are contacted with a sample suspected of containing the nucleic acid sequence and if they form duplexes, they are hydrolysed. This may be done, for example during an amplification reaction. AMP generated as a result of the hydrolysis is converted to ATP. The ATP may then be detected using bioluminescent reagents. Inclusion of modified adenosine in at least one probe means that the signal arising from one probe will give rise to a different and distinguishable bioluminescent signal thus enabling the use of for example an internal control in bioluminescently-reported nucleic acid tests. | 2008-09-25 |
| 20080233589 | Complementation Systems Utilizing Complexes of Heteroproteins - The present invention provides heterologous complementation systems and methods of using the systems to detect molecular interactions. In particular, the heterologous complementation systems comprise polypeptide fragments derived from heterologous polypeptides. If a molecular interaction occurs, then the heterologous polypeptide fragments are able to associate and produce a detectable signal. | 2008-09-25 |
| 20080233590 | Device For the Analysis of Liquid Samples - The present invention relates to devices for the analysis of liquid samples, comprising a rotational-symmetric rotor ( | 2008-09-25 |
| 20080233591 | METHOD AND TEST KIT FOR QUANTITATIVE DETERMINATION OF POLYNUCLEOTIDES IN A MIXTURE - The invention relates to a method and test kit for quantitative determination of the amounts or relative proportions of polynucleotides in a mixture. The invention enables assessment of dynamic variations in a mixed population of organisms using affinity aided solution hybridization. The test kit comprises organized pools of polynucleotide probes having approximately the same number of nucleotides, which are distinguishable using resolution enabling tags providing the probes with different sizes. The resolution enabling tags may simultaneously act as tracer, affinity or primer tags. The probes are allowed to hybridize with affinity tagged analyte polynucleotides. The result is hybrids, recoverable on separation aiding tools provided with counterparts of the affinity tag. After the quantitative release of the probes, the individual probes can be amplified and recorded. The method and test kit are useful for determining hygienic and epidemiologic situations and evaluating the effect of antibiotic treatment and sanitary measures. | 2008-09-25 |
| 20080233592 | Assay Method for Group Transfer Reactions - The present invention relates to methods for detecting, quantifying and high throughput screening of donor-products and the catalytic activities generating the donor-products in group-transfer reactions catalyzed by adenosine triphosphatase (ATPase) or guanine triphosphatase (GTPase). The invention further provides immunoassays, antibodies and kits that may be used to practice the methods of the invention. | 2008-09-25 |
| 20080233593 | Pseudo-Tissue for Quality Control and Quality Control Method Using Same - A pseudo-tissue for quality control is described, which includes a nucleic acid component selected from the group consisting of a nucleic acid and a cell including a nucleic acid, and a gel for holding nucleic acid component. | 2008-09-25 |
| 20080233594 | Method For Detecting An At Least Bivalent Analyte Using Two Affinity Reactants - A method for the determination of an analyte which is a) present in a liquid sample 1 suspected of containing the analyte, and b) at least bivalent with respect to simultaneous affinity binding of at least two binding structures BSs. The method comprises formation of an affinity complex that comprises the analyte and an affinity reactant 1 that is immobilized to a solid phase. The method comprises the steps of: (i) providing a microfluidic flow path that comprises a reaction cavity containing a solid phase to which affinity reactant 1 is immobilized, (ii) providing sample 1 upstream of the cavity and flowing it through the cavity for the formation of the affinity complex under flow conditions, (iii) measuring the amount of complex formed in the solid phase by a) incorporating an analytically detectable and soluble affinity reactant 2 that comprises a binding structure BS into the complex subsequent to step (ii), and b) measuring the amount of affinity reactant 2 incorporated. | 2008-09-25 |
| 20080233595 | METHOD FOR DIAGNOSING INTERTILITY - The invention relates to methods for diagnosing conditions characterized by altered expression of a pregnancy related serine protease (PRSP) protein in a mammal. Such conditions include infertility caused by an inability to achieve or sustain embryo implantation, an inability to sustain a pregnancy, early abortion, insufficient placentation, pre-eclampsia, or intrauterine growth restriction. The methods include detecting expression of PRSP, such as SEQ ID NP33. Detection may be accomplished using a PRSP-specific antibody. | 2008-09-25 |
| 20080233596 | CHIMERIC HUMAN T1R1 TASTE RECEPTOR POLYPEPTIDES AND COMPOSITIONS CONTAINING SAME - Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in taste signaling, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for representing taste perception of a particular tastant in a mammal are also described, as are methods for generating novel molecules or combinations of molecules that elicit a predetermined taste perception in a mammal, and methods for simulating one or more tastes. Further, methods for stimulating or blocking taste perception in a mammal are also disclosed. | 2008-09-25 |
| 20080233597 | Method of Detecting or Differentiating Rheumatoid Arthritis and Method of Determining Stage of Disease or Degree of Dysfunction with Regard to Rheumatoid Arthritis - A method of readily detecting or differentiating rheumatoid arthritis, which has so far been diagnosed in a comprehensive manner based on various tests and clinical symptoms, and a method of readily and objectively estimating the stage of disease and the degree of dysfunction with regard to rheumatoid arthritis are provided. | 2008-09-25 |
| 20080233598 | Nucleic acid and corresponding protein entitled 121P2A3 useful in treatment and detection of cancer - A novel gene (designated 121P2A3) and its encoded protein, and variants thereof, are described wherein 121P2A3 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 121P2A3 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 121P2A3 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 121P2A3 can be used in active or passive immunization. | 2008-09-25 |
| 20080233599 | IMMUNOGENIC GLYCOPEPTIDES, SCREENING, PREPARATION AND USES - The invention concerns immunogenic glycopeptides derived from pathogenic microorganisms, useful for vaccination and diagnosis of infections caused by said pathogenic microorganisms (bacteria or fungi), and methods for selecting them and preparing them. Said glycopeptides are selected in the group consisting of: a1) glycopeptides essentially consisting of a glycosylated T epitope, comprising 14 to 25 amino acids, among which at least a neutral amino acid is bound to a di- or to a trisaccharide (glycoside linkage) and at least 15% among said amino acids are proline, one of the proline being located in position −1 to −4, relative to the position of said neutral amino acid, which glycopeptides are: exhibited by a class II MHC molecule, specifically identified by T CD+4 lymphocytes induced by immunisation with the native glycopeptide from which they are derived, but are not identified by the T CD+4 lymphocytes induced by immunisation with a non-glycosylated peptide of same sequence and capable of inducing a proliferation of said T CD+4 lymphocytes by which they are identified and the secretion of cytokines by said lymphocytes and b1) glycopeptides having a sequence of 15 to 39 amino acids including the sequence of the glycopeptide as defined in a1), excluding the glycopeptide of sequence SEQ ID NO:11. | 2008-09-25 |
| 20080233600 | Method and Kit for the Measurement of Neutrophil Cell Activation - The present invention is related to accurate detection methods for the measurement only of myelopexidase (MPO) levels or neutrophils, preferably equine neutrophils, in complex biological samples. The present invention is further related to ELISA and SIEFED assays for such detection. SIEFED detection sensitivity of active peroxidase activity was found to be enhanced by the addition of nitrite. Such MPO measurement finds its use in many applications such as the prediction, diagnosis and/or monitoring of pathologies correlated with neutrophil activation and/or destruction; the evaluation of drugs and/or immunomodulators; the assessment of immune responses, either natural and/or after treatment with immunomodulators and/or drugs; and the study of cells and their ability to fight microorganisms and/or to destroy them. | 2008-09-25 |
| 20080233601 | POLYMERIZABLE CHEMILUMINESCENT COMPOUNDS - Disclosed are compounds having the formula: | 2008-09-25 |
| 20080233602 | Detecting and profiling molecular complexes - Methods are provided for detecting the formation of complexes of molecules, especially proteins, in a sample, such as a cell or tissue lysate. In one aspect, a cleaving probe specific for a first protein in a complex and one or more binding compounds specific for one or more second proteins in a complex are provided. Upon binding, the cleaving probe is induced to generate an active species, such as singlet oxygen, that cleaves molecular tags attached to the binding compounds only in the local region of the cleaving probe. The released molecular tags are separated from the assay mixture and from one another to provide a readout that is related to the number and types of proteins present in the complex. | 2008-09-25 |
| 20080233603 | Fluorine NMR spectroscopy for biochemical screening - High-Throughput Screening (HTS) of large compound libraries is the method of drug-lead discovery. It is now well accepted that for a functional assay, quality is more important than quantity. A biochemical NMR method originally proposed by Percival and Withers (Biochemistry, 1992, 31, 498-505) is extended to the screening of Ser/Thr kinases. The method requires the presence of a CF | 2008-09-25 |
| 20080233604 | Methods For Identifying Compounds Capable of Modulating the Hydrolase Activity of Clca Protein - Methods for identifying compounds capable of modulating the hydrolase activity of a CLCA protein include screening and computer modelling methods. The compounds, including antibodies, may be useful as therapeutic agents to treat a variety of diseases. | 2008-09-25 |
| 20080233605 | Method of Assaying Glycated Protein - The present invention provides a convenient, efficient method for assaying glycated protein, fructosyl peptide, or fructosyl amino acid which can be performed with reduced effect of fructosyl lysine compounds. The invention also provides a reagent for the assay. | 2008-09-25 |
| 20080233606 | USE OF RAMAN SPECTROSCOPY IN ENZYME ACTIVITY ASSAYS - Provided herein are assays for detecting enzyme activity using Raman Spectroscopy. | 2008-09-25 |
| 20080233607 | Cell Culture Device - The invention provides cell culture devices comprising a channel, the channel comprising one or more inlets and one or more outlets, and a cell retention chamber defined by an internal surface of the channel and a plurality of projections extending therefrom. The invention further provides methods of use relating to such cell culture devices. | 2008-09-25 |
| 20080233608 | GENES AND PROTEINS INVOLVED IN LIPID REMODELING OF GPI-ANCHORED PROTEINS AND THE USE THEREOF - This invention provides proteins and genes thereof involved in the GPI lipid remodeling process and, thereby and constructing a system for screening for useful substances such as anticancer agents and a system for detecting abnormalities in the GPI lipid remodeling process. | 2008-09-25 |
| 20080233609 | Spirolactam Targeting Compounds and Related Compounds - Spirolactam targeting compounds, related compounds, uses of such compounds, and methods of making such compounds are disclosed. | 2008-09-25 |
| 20080233610 | SOMATIC CELL REPROGRAMMING - The present invention relates to methods for reprogramming a somatic cell to pluripotency by administering into the somatic cell at least one or a plurality of potency-determining factors. The invention also relates to pluripotent cell populations obtained using a reprogramming method. | 2008-09-25 |
| 20080233611 | Orthogonal Translation Components for the in Vivo Incorporation of Unnatural Amino Acids - The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate unnatural amino acids into proteins produced in eubacterial host cells such as | 2008-09-25 |
| 20080233612 | Fungal Hosts for Expression of Recombinant Products - An isolated mutant | 2008-09-25 |
| 20080233613 | Polypeptides having beta-glucosidase activity and polynucleotides encoding same - The present invention relates to isolated polypeptides having beta-glucosidase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods for producing and using the polypeptides. | 2008-09-25 |
| 20080233614 | PRODUCTION OF RECOMBINANT COLLAGENASES COLG AND COLH IN ESCHERICHIA COLI - The present invention provides codon-optimized genes designed to help maximize heterologous protein expression level. The present invention provides codon-optimized recombinant colG and colH collagenase sequences. | 2008-09-25 |
| 20080233615 | NUCLEIC ACID ENCODING TWO-COMPONENT SENSING AND REGULATORY PROTEINS, ANTIMICROBIAL PROTEINS AND USES THEREFOR - Stress-related nucleic acid molecules and polypeptides and fragments and variants thereof are disclosed in the current invention. In addition, stress-related fusion proteins, antigenic peptides, and anti-stress-related antibodies are encompassed. The invention also provides recombinant expression vectors containing a nucleic acid molecule of the invention and cells into which the expression vectors have been introduced. Methods for producing the polypeptides and methods of use for the polypeptides of the invention are further disclosed. | 2008-09-25 |
| 20080233616 | Method for Carrying Out the Selective Evolution of Proteins in Vitro - The present invention relates to the production of variants of a protein in an in vitro evolution method, comprising the steps: (A) provision of an in vitro expression system comprising (i) a nucleic acid sequence S which codes for a protein Y which is to be varied, (ii) a target molecule X which is able to bind to the protein Y and/or at least one variant Y′ thereof, (iii) an RNA polymerase (Pol) which is able to transcribe the nucleic acid sequence S, (iv) a reverse transcriptase (RT) which is capable of reverse transcription of transcripts of the nucleic acid sequence S, where either the target molecule X is coupled to Pol and the protein Y is coupled to RT, or the target molecule X is coupled to RT and the protein Y is coupled to Pol, (B)incubation of the in vitro expression system from (A) under conditions which enable transcription, reverse transcription and translation to form variants Y′ of the protein Y and nucleic acid sequences S′ coding therefor, and which favor the formation of variants Y′ with improved binding properties for the target molecule X, (C) isolation and, where appropriate, characterization of those variants Y′ which exhibit improved binding properties for binding to X, and/or isolation of nucleic acid sequence variants S′ coding for Y′. | 2008-09-25 |
| 20080233617 | Process for the Preparation of a Aspartate and Derived Amino Acids Like Lysine, Threonine, Isoleucine, Methionine, or Homoserine Employing Microorganism with Enhanced Isocitrate Lyase and/or Malate Synthase Expression - The present invention relates to increasing the product of aspartate or aspartate-derived metabolites by boosting the activity of the glyoxylate shunt. This is accomplished by increasing the activity of glyoxylate shunt specific enzymes and decreasing the activity of reactions consuming glyoxylate and its precursors. | 2008-09-25 |
| 20080233618 | Biosynthetic gene cluster for leptomycins - Polypeptides and domains of leptomycin polyketide synthase and the nucleic acids encoding them are provided. Methods to prepare leptomycin, leptomycin analogs, and leptomycin derivatives are described, as are methods to prepare other polyketides using the nucleic acids encoding leptomycin polyketide synthase domains or modifying enzymes. | 2008-09-25 |
| 20080233619 | Process For the Enantioselective Enzymatic Reduction of Keto Compounds - The present invention relates to a process for the enantioselective enzymatic reduction of keto compounds which is carried out in two phases and uses 4-methyl-2-pentanol, 5-methyl-2-hexanol and/or 2-heptanol for coenzyme regeneration. | 2008-09-25 |
| 20080233620 | Novel Transformant and Process for Producing Polyester Using the Same - The present invention provides a process for producing yeast excellent in cell productivity and gene manipulation of which is easy, being added with nutritional requirement by disrupting only a specific gene, and a transformant thereof. Moreover, the present invention also provides a process for producing a gene expression product, particularly a polyhydroxyalkanoic acid. | 2008-09-25 |
| 20080233621 | Method For Producing Alcohol and Carboxylic Acid Having Optical Activity - It is an object of the present invention to provide an inexpensive and efficient industrial method for obtaining (S)-2-pentanol, (S)-2-hexanol, 1-methylalkyl malonic acid and 3-methyl carboxylic acid at a high optical purity. The present invention provides a method of producing (S)-2-pentanol or (S)-2-hexanol which comprises allowing certain types of microorganisms or transformed cells, a product obtained by treating said microorganisms or cells, a culture solution of said microorganisms or cells, and/or a crude purified product or purified product of a carbonyl reductase fraction obtained from said microorganisms or cells, to act on 2-pentanone or 2-hexanone. | 2008-09-25 |
| 20080233622 | NOVEL METHODS FOR PRODUCTION OF 5-EPI-BETA-VETIVONE, 2-ISOPROPYL-6,10-DIMETHYL-SPIRO[4.5]DECA-2,6-DIEN-8-ONE, AND 2-ISOPROPYL-6,10-DIMETHYL-SPIRO[4.5]DECA-1,6-DIEN-8-ONE - The present invention is directed to novel methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one, which are useful for their fragrant qualities. In one embodiment the present invention describes a method for production of 5-epi-β-vetivone by the use of premnaspirodiene as starting material. In another embodiment the present invention describes a method for production of 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one by the use of premnaspirodiene as starting material. In yet another embodiment the present invention describes a novel method for production of premnaspirodiene from a terpene substrate. | 2008-09-25 |
| 20080233623 | GENETICALLY MODIFIED HOST CELLS FOR INCREASED P450 ACTIVITY LEVELS AND METHODS OF USE THEREOF - The present invention provides genetically modified host cells that exhibit modified activity levels of one or more gene products such that, when a cytochrome P450 enzyme is produced in the genetically modified host cell, the modified activity levels of the one or more gene products provide for enhanced production and/or activity of the cytochrome P450 enzyme. The present invention provides methods of producing a cytochrome P450 enzyme in a host cell, generally involving culturing a subject genetically modified host cell in a suitable culture medium. The present invention further provides methods of producing a product of a P450-dependent oxidation, generally involving culturing a subject genetically modified host cell in a suitable culture medium. | 2008-09-25 |
| 20080233624 | Apparatus and method for biohydrogen production - An apparatus for biohydrogen production comprises a cell with an anion-selective membrane dividing the cell into first and second compartments. In use, the first compartment is placed into fluid communication with a bacterial fermentation culture and the second compartment is placed into fluid communication with a photoheterotrophic bacterial culture. Application of a potential difference to the cell allows organic acids produced by the bacterial fermentation culture to cross the membrane and be supplied to the photoheterotrophic bacterial culture. Regulation of the current through the cell controls the quantity of ammonium transferred with the organic acids. | 2008-09-25 |
| 20080233625 | Dietary supplements for regulating the central nervous system - Compositions comprising a plurality of yeast cells, wherein said plurality of yeast cells have been cultured in the presence of an alternating electric field having a specific frequency and a specific field strength for a period of time sufficient to increase the capability of said plurality of yeast cells to regulate the central nervous system. Also included are methods of making such compositions. | 2008-09-25 |
| 20080233626 | Enhanced broad-spectrum UV radiation filters and methods - The present invention obtains from the discovery that combining traditional UV pigments, organic chemicals, or both, combined with NA, creates a broad spectrum UV absorbing additive that is much more efficient than using any of the ingredients by themselves. Methods for producing NA-coated particles as a UV protection additive to paints, fiberglass, plastic, polymers, siloxanes/silicates/reactive silanols, sealants or other film forming coatings or penetrating fluids and solid articles are contemplated in this invention as well as the coatings, sealants and other protectants and the coated and/or finished articles themselves. | 2008-09-25 |
| 20080233627 | Nicotianamine synthase and gene encoding the same - A nicotianamine synthase is isolated and purified. Then the gene of this enzyme is cloned and the base sequence and amino acid sequence thereof are determined. This gene is employed in constructing plants, in particular, grass plants highly tolerant to iron-deficiency. A nicotianamine synthase involved in the mugineic acid biosynthesis pathway; the amino acid sequence thereof; a gene encoding the same; a vector containing this gene; cells transformed by the vector; a process for producing nicotianamine by using the same; plants transformed by the gene encoding the nicotianamine synthase; and an antibody against the nicotianamine syntase. | 2008-09-25 |
| 20080233628 | Incorporation of type III polyketide synthases into multidomain proteins of the type I and III polyketide synthase and fatty acid synthase families - Recombinant fusion proteins in which intermediates are covalently bound to the fusion proteins and transferred between domains of the fusion proteins are provided. The fusion proteins include proteins having type I polyketide or fatty acid synthase domains fused with type III polyketide synthase domains. Methods of making such recombinant fusion proteins and methods using such proteins to produce polyketide and other products are described. | 2008-09-25 |
| 20080233629 | ENZYMES FOR BIOPOLYMER PRODUCTION - In order to optimize the flux or flow of carbon intermediates from normal cellular metabolism into PHAs it is desirable to optimize the expression of the enzymes of the PHA biosynthetic pathway. Gene fusions are genetic constructs where two open reading frames have been fused into one and encode hybrid proteins and in some cases bifunctional hybrid enzymes. Linkers may be added to spatially separate the two domains of the hybrid protein. In the case of enzymes which catalyse successive reactions in a pathway, the fusion of two genes results in bringing two enzymatic activities into close proximity to each other. When the product of the first reaction is a substrate for the second one, this new configuration of active sites may result in a faster transfer of the product of the first reaction to the second active site with a potential for increasing the flux through the pathway. | 2008-09-25 |
| 20080233630 | Apparatus and Method for Magnetically Separating Cells From Mixture - According to the conventional process of separating necessary cells from a cell mixture containing specific cells tagged with magnetic beads, there is a problem in that separation process is complicated when the separation efficiency is high whereas the separation efficiency is relatively low when the separation process is simplified. The present invention provides an apparatus and method for separating cells from a cell mixture simply and efficiently through the processes of creating a cell mixture layer between upper and lower plates by adjusting a gap between the upper and lower plates and of adjusting a thickness of the created layer and separating the layer while applying a magnetic field to the layer from the upper plate, wherein the lower plate is provided with a cell mixture holding portion, in which the cell mixture containing specific cells tagged with magnetic beads is accommodated in an upwardly convex shape, at a top surface thereof and the upper plate is positioned above the lower plate to face each other and to adsorb the cell mixture accommodated in the cell mixture holding portion of the lower plate into a bottom surface thereof. | 2008-09-25 |
| 20080233631 | Ventilating/Stirring Culture Tank - The invention provides a ventilating/stirring culture tank that has a longitudinal tubular container | 2008-09-25 |
| 20080233632 | Process for Labeling and Purification of Nucleic Acids of Interest Present in a Biological Sample to be Treated in a Single Reaction Vessel - The present invention relates to a process for labeling and purification of nucleic acids of interest present in a biological sample to be treated, comprising:
| 2008-09-25 |
| 20080233633 | Sheathing for Packaging a Predetermined Volume of a Biological Substance Designed to be Immersed in a Liquid Cryogenic Agent - The invention concerns a sheathing for packaging a predetermined volume of a biological substance designed to be immersed in a liquid cryogenic agent comprising a thin tube ( | 2008-09-25 |
| 20080233634 | NUCLEIC ACID DETECTION DEVICE - A nucleic acid detection device is provided with a closed channel formed of a first channel portion, through which a washing reagent storage section for storing a washing reagent for washing a detection section for nucleic acid detection communicates with the detection section, and a second channel portion through which a pretreatment section for nucleic acid treatment communicates with the detection section. The closed channel is connected with a gas inlet/outlet path for communication with the outside. The gas inlet/outlet path is blocked by a sealing mechanism before nucleic acid detection. In storing a pretreatment reagent and the washing reagent frozen, the gas inlet/outlet path is kept open and connected to the channel. Thus, there is provided a nucleic acid detection device having a structure for preventing leakage of nucleic acid samples to the outside and which can be stored for a long period of time with the reagents therein. | 2008-09-25 |
| 20080233635 | Methods and Apparatus for High Purity X-Chromosome Bearing and Y-Chromosome Bearing Populations Of Spermatozoa - Isolated non-naturally occurring populations of spermatozoa ( | 2008-09-25 |
| 20080233636 | Humidity-controlled gas-borne matter collection device - A system includes a device for collecting gas-borne matter therein and a humectant provided external to the device for maintaining a desired humidity level for collected matter in the device. | 2008-09-25 |
| 20080233637 | MELANOMA ANTIGENS AND THEIR USE IN DIAGNOSTIC AND THERAPEUTIC METHODS - The present invention provides a nucleic acid sequence encoding a melanoma antigen recognized by T lymphocytes, designated MART-1. This invention further relates to bioassays using the nucleic acid sequence, protein or antibodies of this invention to diagnose, assess or prognoses a mammal afflicted with melanoma or metastata melanoma. This invention also provides immunogenic peptides derived from the MRT-1 melanoma antigen and a second melanoma antigen designated gp100. This invention further provides immunogenic peptides derived from the MART-1 melanoma antigen or gp100 antigen which have been modified to enhance their immunogenicity. The proteins and peptides provided can serve as an immunogen or vaccine to prevent or treat melanoma. | 2008-09-25 |
| 20080233638 | PAAD domain-containing polypeptides, encoding nucleic acids, and methods of use - The invention provides isolated nucleic acid molecules encoding PAAD-domain containing polypeptides and functional fragments thereof, including fragments containing PAAD domains, NACHT domains and ARED domains, encoded polypeptides, and antibodies. Also provided are methods of identifying polypeptides and agents that associate with a PAAD-domain containing polypeptide or fragment thereof, or that alter an association of a PAAD domain-containing polypeptides. Further provided are methods of identifying agents that modulate PAAD domain-mediated inhibition of NFκB activity, or modulate an activity of a NACHT domain of a PAAD domain-containing polypeptide. Also provided are methods of modulating NFκB transcriptional activity in a cell, and methods of altering expression of a PAAD domain-containing polypeptide in a cell. | 2008-09-25 |
| 20080233639 | Fusion protein delivery system and uses thereof - The present invention provides a composition of matter, comprising: DNA encoding a viral Vpx protein fused to DNA encoding a protein. In another embodiment of the present invention, there is provided a composition of matter comprising: DNA encoding a viral Vpr protein fused to DNA encoding a protein. The present invention further provides DNA, vectors and methods for expressing a lentiviral pol gene in trans, independent of the lentiviral gag-pol. A gene transduction element is optionally delivered to a lentiviral vector according to the present invention. Also provided are various methods of delivering a virus inhibitory molecule to a target in an animal. Further provided is a pharmaceutical composition. | 2008-09-25 |
| 20080233640 | Prostate Stem Cell - We describe a method for the isolation of prostate stem cells, typically prostate stem cells which express CD 133 antigen; stem cells and cancer stem cells isolated by the method and their use. | 2008-09-25 |
| 20080233641 | Simultaneous modulation of multiple genes - Disclosed herein are compositions and methods that regulate expression of two or more endogenous genes. | 2008-09-25 |
| 20080233642 | MAMMALIAN IMMORTALIZED LIVER CELL - The present invention provides a mammalian immortalized liver cell obtained by transferring a cell proliferation factor gene located between a pair of site-specific recombination sequences into a mammalian liver cell. | 2008-09-25 |
| 20080233643 | Differentiation of Cd34 Positive Cell to Megakaryocyte and Multiplication - An object of the present invention is to provide a method for more efficiently differentiating CD34 | 2008-09-25 |
| 20080233644 | Chimeric Transcription Factor Decoy Oligonucleotides - A method for the treatment of the brain cancer glioblastoma multiforme (GBM) is provided. The method involves decreasing the expression of Matrix Metalloproteinase-1 (MMP-1) expression by providing transcription factor decoy nucleotides that mimic single nucleotide polymorphisms responsible for MMP-1 overexpression. | 2008-09-25 |
| 20080233645 | Methods and Compositions of Ig20 and Denn-Sv Splice Variants - Methods and compositions relating to IG20 expression, splice variants of IG20, effects of endogenous DENN-SV function with respect to processes regulating cell proliferation, cell survival and cell death are disclosed. | 2008-09-25 |
| 20080233646 | Human DR4 antibodies and uses thereof - Human Death Receptor 4 (DR4) antibodies are provided. The human DR4 antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the DR4 antibodies are also provided. | 2008-09-25 |
| 20080233647 | NOVEL NEUROTROPHIC FACTORS - The invention relates to neublastin neurotrophic factor polypeptides, nucleic acids encoding neublastin polypeptides, and antibodies that bind specifically to neublastin polypeptides, as well as methods of making and methods of using the same. | 2008-09-25 |
| 20080233648 | BIASING OF CELLS TOWARD RETINAL, CORNEAL OR LENS DEVELOPMENT - Methods are described that bias cells, such as potent and multipotent stem cells, by transfection with a nucleic acid sequence, to differentiate to a desired end-stage cell or a cell having characteristics of a desired end-stage cell. In particular embodiments, human neural stem cells or mesenchymal stem cells are transfected with vectors comprising genes in the homeobox family of transcription factor developmental control genes, and this results in a greater percentage of resultant transformed cells, or their progeny, differentiating into a desired end-stage cell or a cell having characteristics of a desired end-stage cell. | 2008-09-25 |
| 20080233649 | PANCREATIC STEM CELLS - Pancreatic progenitor cells isolated from the pancreas of a mammal. The invention also includes pancreatic cells or neural cells differentiated from the pancreatic progenitor cells. | 2008-09-25 |
| 20080233650 | Method for propagating adenoviral vectors encoding inhibitory gene products - The invention provides a method of propagating an adenoviral vector. The method comprises (a) providing a cell comprising a cellular genome comprising a nucleic acid sequence encoding a tetracycline operon repressor protein (tetR), and (b) contacting the cell with an adenoviral vector comprising a heterologous nucleic acid sequence encoding a toxic protein. The heterologous nucleic acid sequence is operably linked to a promoter and one or more tetracycline operon operator sequences (tetO), and expression of the heterologous nucleic acid sequence is inhibited in the presence of tetR, such that the adenoviral vector is propagated. The invention also provides a system comprising the aforementioned cell and adenoviral vector. | 2008-09-25 |
| 20080233651 | Method and medicament for inhibiting the expression of a given gene - The present invention relates to the specific inhibition of expression of a target gene in mammals using a short double stranded RNA. The dsRNA is less than 49 nucleotides in length and has a nucleotide sequence which is complementary to at least a part of the target gene. The dsRNAs of the present invention are useful for treating diseases, for example, cancer, viral diseases or neurodegenerative diseases. | 2008-09-25 |
| 20080233652 | Set of Calibration Standards - The present invention relates to a standard calibration set comprising at least three calibration standards that consist of a molded article made of a thermoplastic polymer which contains the elements Cd, Cr, Pb, Hg and Br, with the Cr:Pb:Hg:Br:Cd ratio being different in each of the three calibration standards, and to a method for manufacturing said calibration standards and their use in X-ray fluorescence analysis. | 2008-09-25 |
| 20080233653 | System and Method for Processing Chemical Substances, Computer Program for Controlling Such System, and a Corresponding Computer-Readable Storage Medium - The invention is directed to a system and a method for processing chemical substances, a computer program for controlling such system, and a corresponding computer-readable storage medium, which can be used, in particular, to flexibly adapt synthesis devices, in particular for radioactive chemicals or radioactive pharmaceutical products, to different process flows and to make the synthesis devices usable for research and routine operation. | 2008-09-25 |
| 20080233654 | Tagging System - A method of tracing an aqueous liquid, particularly an aqueous urea used for addition to a selective catalytic reduction system to remove NOx from diesel exhaust includes adding a tracer comprising a pre-determined amount of a phenol to the liquid. The liquid can subsequently be identified by reacting a sample with a reagent containing a predetermined amount of 4-aminoantipyrine in the presence of an initiating compound such that the reaction between the reagent and a phenol in the liquid produces a chromophore and measuring the absorbance of the resulting solution of the chromophore. | 2008-09-25 |
| 20080233655 | Screening For Lysosomal Storage Disease Status - A method of ascertaining the LSD (Lysosomal storage disorder) status of an individual comprising taking a tissue or body fluid sample from the individual and estimating a level in the sample of each of three or more compound indicators. The indicators reflect the level of respectively each of three or more lipid containing storage associated compounds. The levels are used to calculate an LSD index number which is then compared with a standard to provide an assessment of the LSD status of the individual. The indicator compounds are conveniently phospholipids, glycolipids or lipopolysaccharide species measured by mass spectrometry. The method may be used to ascertain the nature of the disorder from which the individual stuffers, and its severity. It may also be used to monitor the progress of treatment and to ascertain the prospects of an individual contracting an LSD by providing a subclinical indicators for the condition. | 2008-09-25 |
| 20080233656 | Method For Detecting a Fuel Additive Component - A process for qualitatively or quantitatively detecting a fuel additive component which is part of an analyte comprising a fuel and/or further fuel additive components, by contacting the analyte with an indicator and determining the change, caused by the interaction between fuel additive component and indicator, in the color properties of the indicator in the analyte. | 2008-09-25 |
| 20080233657 | METHODS TO PREDICT THE OUTCOME OF TREATMENT WITH ANTIDEPRESSANT MEDICATION - The invention provides a method for determining the outcome of treatment with an antidepressant medication in a patient. In particular, the invention provides a method of screening patients to identify those patients with a decreased risk of non-response to treatment with antidepressant medication comprising: (a) obtaining a sample of genetic material from the patients, and (b) assaying the sample for the presence of a genotype in the patients which is associated with a decreased risk of non-response to treatment with antidepressant medication, wherein the genotype is characterized by a polymorphism in a HTR2A, GRIK4, BCL2, or a combination thereof. | 2008-09-25 |
| 20080233658 | Environmental Fluorescent Sensors - The present disclosure relates to a fluorescence marker such as quantum dots and their use as sensors which may rely upon a change in fluorescence output upon exposure to a given environmental condition. The variation in fluorescence output may then be utilized as an indication of exposure to a given environmental condition. | 2008-09-25 |
| 20080233659 | PROCESS OF SCREENING FOR ALPHA-THALASSEMIA CARRIER USING IMMUNOCHROMATOGRAPHIC STRIP TEST - The invention provides a device and method for the rapid identification of patients suspected of having thalassemia. The invention provides a test strip for the aqueous detection of thalassemia related proteins in whole blood. The test strip includes antibodies specific to the gamma 4, (γ4) protein and provides easy visual discrimination between a positive result and a negative result. The invention can be used in remote or clinical settings. | 2008-09-25 |
| 20080233660 | Solid phase labeling method - The invention provides for the labeling of antibodies with a fluorescent label, using a solid support comprising an affinity for an Fc portion of an antibody. Thus, the invention provides a method for labeling an antibody or fragment thereof with a fluorescent label, comprising the steps of immobilizing an antibody on the solid support and covalently coupling a fluorescent label to the immobilized antibody, as well as a kit for performing such method. | 2008-09-25 |
| 20080233661 | Methods and Systems For Lithography Alignment - Methods and systems for lithographically exposing a substrate based on a curvature profile of the substrate. | 2008-09-25 |
| 20080233662 | Advanced Process Control for Semiconductor Processing - An advanced process control (APC) method for semiconductor fabrication is provided. A first substrate and a second substrate are provided. The first substrate and the second substrate include a dielectric layer. A first etch process parameter for the first substrate is determined. A trench is etched in the dielectric layer of the first substrate using the first etch process parameter. At least one aspect of the etched trench of the first substrate is measured. A second etch process parameter for the second substrate is determined using the measured aspect of the etched trench of the first substrate. A planarization process parameter for the first substrate is determined also using the measured aspect of the etched trench of the first substrate. | 2008-09-25 |
| 20080233663 | SINGULATED BARE DIE TESTING - There is testing of individual dice prior to their inclusion in a multi-chip package. A wafer is sawn into individual dice and the dice are placed onto a die tray. If the tray is not full, then dice can be added that originate from other wafers. Contacts perform diagnostic tests upon the dice to determine if individual dice function as expected. Mapping talkes place to distinguish between dice that passed the diagnostic test and those that did not. Multiple tests can take place in series, where various forms of consolidation and mapping takes place. Passing dice can become part of a multi-chip package while failing dice can be re-screened or scrapped. | 2008-09-25 |
| 20080233664 | Semiconductor integrated circuit production method and device - A semiconductor integrated circuit production method prepares an SOI layer thickness database that correlates measurement data of each SOI layer thickness with each SOI substrate identification data. The production method extracts the measurement data for each SOI substrate from the SOI layer thickness database, and carries out layer thickness adjustment surface treatment for the SOI substrates based on these data. A semiconductor integrated circuit production device includes an SOI layer thickness database storage unit for storing the SOI layer thickness database, and a layer thickness adjustment conditions control unit for extracting the measurement data for each SOI substrate from the SOI layer thickness database and deciding conditions for the layer thickness adjustment surface treatment based on these data. The semiconductor integrated circuit production device also includes a surface treatment unit that adjusts SOI layer thickness by carrying out the surface treatment on the SOI layers in accordance with the decided conditions. | 2008-09-25 |
| 20080233665 | METHOD OF MANUFACTURING A SEMICONDUCTOR DEVICE - A method of manufacturing a semiconductor device including: forming a semiconductor layer on a substrate with transistor and capacitor formation regions; forming first and second photo resist patterns at the transistor and capacitor formation regions, respectively, the second photo resist pattern having a thickness less than that of the first photo resist pattern; patterning the semiconductor layer using the first and second photo resist patterns as a mask; removing the second photo resist pattern to expose the semiconductor layer at the capacitor formation region; implanting ions in the exposed semiconductor layer to form a first electrode of a capacitor; removing the first photo resist pattern; forming a gate electrode at the transistor formation region; forming an second electrode at the capacitor formatting region; and forming a source region and a drain region at the semiconductor layer formed at both sides of the gate electrode. | 2008-09-25 |
| 20080233666 | Light emitting diode package with metal reflective layer and method of manufacturing the same - The invention relates to an LED package having a metal reflective layer for focusing and emitting light through a side of the package, and a manufacturing method of the same. The LED package includes a substrate with an electrode formed thereon, a light emitting diode chip disposed on the substrate, and an encapsulant covering the LED chip and the substrate to protect the LED chip. The LED package also includes a metal reflective layer surrounding side surfaces of the encapsulant to form a light transmitting surface on a top surface of the encapsulant. The invention minimizes light loss, improves luminance, can be mass-produced as a PCB type, and adopts EMC transfer molding to minimize irregular color distribution, thereby improving optical quality. | 2008-09-25 |
| 20080233667 | MICRODISPLAY PACKAGING SYSTEM - Some embodiments provide a microdisplay integrated circuit (IC), a substantially transparent protective cover coupled to the microdisplay IC, and a base coupled to the microdisplay IC. Thermal expansion characteristics of the base may be substantially similar to thermal expansion characteristics of the protective cover. According to some embodiments, at least one set of imaging elements is fabricated on an upper surface of a semiconductor substrate, and a base is affixed to a lower surface of the semiconductor substrate to generate substantially negligible mechanical stress between the semiconductor substrate and the base. | 2008-09-25 |
| 20080233668 | METHOD FOR MANUFACTURING SEMICONDUCTOR OPTICAL DEVICE - A method for manufacturing a semiconductor optical device includes: forming a laminated semiconductor structure of GaN-based materials on a semiconductor wafer, the laminated semiconductor structure forming a laser diode of GaN-based materials, including an active layer having a quantum well structure; cleaving the semiconductor wafer including the laminated semiconductor structure to expose a cleaved end face of the laminated semiconductor structure; and forming an SiO | 2008-09-25 |
| 20080233669 | Method for Manufacturing Light-Emitting Device - A full-color light-emitting device is achieved with plural kinds of light-emitting elements in each of which a stacked layer of a first material layer formed selectively with a droplet discharge apparatus and a second material layer formed by vapor-deposition method using the conductive-surface plate on which a layer containing an organic compound is formed is provided between a pair of electrodes. The first material layer is a layer in which an organic compound and a metal oxide which is an inorganic compound are mixed. By adjusting the thickness of the first material layer of each light-emitting element, which is different depending on an emission color, a blue light emission component, a green light emission component, or a red light emission component among a plurality of components for white light emission can be selectively emphasized and taken out by light interference phenomenon. | 2008-09-25 |
