38th week of 2010 patent applcation highlights part 42 |
Patent application number | Title | Published |
20100240062 | METHOD FOR PREPARING AND ANALYZING CELLS HAVING CHROMOSOMAL ABNORMALITIES - The present invention provides methods for preparing cells with highly condensed chromosomes, such as sperm, and methods for detecting and quantifying specific cellular target molecules in intact cells. Specifically, methods are provided for detecting chromosomes and chromosomal abnormalities, including aneuploidy, in intact cells using fluorescence in situ hybridization of cells in suspension, such as sperm cells. | 2010-09-23 |
20100240063 | SYSTEMS AND METHODS FOR DETECTING MULTIPLE OPTICAL SIGNALS - To minimize cross talk in systems and methods for detecting two or more different optical signals emitted from each of a plurality of reaction receptacles, an excitation signal associated with each of the optical signals has a known excitation frequency, and any detected signal having a frequency that is inconsistent with the excitation frequency is discarded. The receptacles are moved relative to optical sensors configured to detect each unique optical signal from an associated receptacle, and to further minimize cross talk, the optical sensors are arranged so that only one reaction receptacle at a time is in a signal detecting position with respect to one of its associated optical sensors, and the optical sensors are grouped by the optical signal they are configured to detect so that a first optical signal is detected from each of the reaction receptacles before a second optical signal is detected from the reaction receptacles. | 2010-09-23 |
20100240064 | DIFFERENTIAL ENZYMATIC FRAGMENTATION - The present invention provides methods for detecting the presence of methylation at a locus within a population of nucleic acids. | 2010-09-23 |
20100240065 | Prolyl Hydroxylase Compositions and Methods of Use Thereof - The invention provides methods and compositions for making and using novel HIF-specific prolyl hydroxylase (HPH) enzymes from rhesus monkeys. | 2010-09-23 |
20100240066 | COMPOUNDS AND METHODS FOR MODULATING CADHERIN-MEDIATED PROCESSES - Peptides comprising a cadherin cell adhesion recognition (CAR) sequence, and compositions comprising such peptides, are provided. Methods of using such peptides for modulating cadherin-mediated processes in a variety of therapeutic contexts are also provided. Methods are also provided for identifying compounds that are capable of modulating cadherin-mediated processes. | 2010-09-23 |
20100240067 | APPARATUS AND METHOD FOR ASSAYING COAGULATION IN FLUID SAMPLES - This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate. | 2010-09-23 |
20100240068 | MARKER PANEL FOR COLORECTAL CANCER - The present invention relates to a method for assessing colorectal cancer (CRC) in vitro including measuring in a sample the concentration and/or activity of a seprase polypeptide and/or fragments thereof and of either anti-p53 and/or osteopontin and/or ferritin, of optionally one or more other marker of CRC, and using the combined measurement result in the assessment of CRC. Furthermore, it especially relates to a method for assessing CRC from a liquid sample, derived from an individual by measuring seprase and at least anti-p53, ferritin and/or osteopontin in the sample. The method according to the present invention can, e.g., be used in the early detection of cancer by screening of asymptomatic individuals or in the surveillance of patients who undergo surgery. | 2010-09-23 |
20100240069 | Drug Discovery Assay for Modulators of HIF-Prolyl Hydroxylase Activity - The present invention relates to a high throughput assay for determining HIF 1α prolyl hydroxylation. | 2010-09-23 |
20100240070 | Nonseparation Assay Methods Using Peroxide Generating Enzymes - Nonseparation assay methods using peroxide generating enzymes in combination with a solid support for analyte detection are disclosed. The present assay methods provide a high degree of sensitivity, are simple and efficient to perform, and are excellent tools for diagnostic and high through-put screening applications. | 2010-09-23 |
20100240071 | Assay for Detection of Transient Intracellular CA2+ - This invention relates to a simple end point assay for detection of transient intracellular Ca | 2010-09-23 |
20100240072 | Cancer Imaging and Treatment - A compound, or a pharmaceutically acceptable salt or ester thereof, comprises the structure: [(P1-S1 | 2010-09-23 |
20100240073 | DETECTION OF FALSE RESULTS IN ASSAYS - Methods and reagents are disclosed for detecting a false result in an assay for determining a concentration of an analyte in a whole blood sample suspected of containing the analyte. The method comprises determining by means of the assay a concentration of the analyte utilizing a hemolyzed portion of the blood sample to obtain concentration value 1 and determining by means of the assay a concentration of the analyte utilizing a non-hemolyzed portion of the blood sample and multiplying the concentration times a hematocrit factor to obtain concentration value 2. A ratio of concentration value 1 divided by concentration value 2 is determined and is compared to a predetermined ratio of known reliability. If the ratio is less than the predetermined ratio, a false result is indicated. | 2010-09-23 |
20100240074 | Set of Yeast Cells, Method of Identifying Target Candidate Molecule, Method of Analyzing Action Mechanism and Screening Method - Provided is a set of yeast gene knockout strains whose drug sensitivity is significantly improved. A set of yeast cells of the invention is a set of yeast cells comprising two or more types of yeast cells, wherein at least one mutually different gene has been deleted or mutated in each of the two or more types of yeast cells, and all of the two or more types of yeast cells are drug hypersensitive yeast cells in which the expression of at least one drug sensitivity-related gene is regulated. | 2010-09-23 |
20100240075 | COMPLEMENT FACTOR H-BASED ASSAYS FOR SERUM BACTERICIDAL ACTIVITY AGAINST NEISSERIA MENINGITIDIS - Assays for detection of bactericidal anti-Neisserial antibodies using a factor H polypeptide having a human amino acid sequence that mediates binding to Neisserial factor H binding protein (fHBp) are provided, as well as non-human animal models of Neisserial infection. | 2010-09-23 |
20100240076 | IMMUNOASSAY INVOLVING MUTANT ANTIGENS TO REDUCE UNSPECIFIC BINDING - A method for a quantitative in vitro analysis to diagnose, to categorise, to predict and/or to monitor the progression of a condition comprising the following steps: a) Obtaining a sample suspected of containing anti-A-antibodies from a subject to be analysed, b) Providing native and mutant antigen A, c) Contacting the sample suspected of containing anti-A-antibodies with mutant antigen A and with native antigen A, d) Detecting the amount of anti-A-antibodies bound to native antigen A after step c), wherein the presence of anti-A-antibodies bound to native antigen A allows the diagnosis, the categorisation, the prediction and/or the monitoring of the progression of a condition. | 2010-09-23 |
20100240077 | METHODS OF ASSESSING CROHN'S DISEASE PATIENT PHENOTYPE BY I2 SEROLOGIC RESPONSE - The invention provides a method of diagnosing or predicting susceptibility to a clinical subtype of Crohn's disease in a subject having Crohn's disease by determining the presence or absence of IgA anti-I2 antibodies in the subject, where the presence of the IgA anti-I2 antibodies indicates that the subject has a clinical subtype of Crohn's disease. In one embodiment, a method of the invention is practiced by further determining the presence or absence in the subject of a NOD2 variant, anti- | 2010-09-23 |
20100240078 | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND/OR PROGNOSIS IN SYSTEMIC INFLAMMATORY RESPONSE SYNDROMES - The present invention relates to methods and compositions for diagnosing SIRS, sepsis, severe sepsis, septic shock, or MODS in a subject, or assigning a prognostic risk for one or more clinical outcomes for a subject suffering from SIRS, sepsis, severe sepsis, septic shock, or MODS, the method comprising performing an immunoassay for CCL23 splice variant. | 2010-09-23 |
20100240079 | GLUCOSE TOLERACE TEST DEVICE - A glucose tolerance test device comprising: a test zone having a means to receive at least first and second blood test samples spaced apart by a predetermined time interval; a timer to measure such a time interval, and for example to measure elapsed time after collection of a said first sample; an indicator to indicate at least that a second test is due, operatively Jinked to the timer so as to make such indication after lapse of a predetermined time interval; a data collector to collect data from the lest zone in relation to each test sample; a data register to store data in relation to each test sample, in data communication with said data collector. A method of use is also described. | 2010-09-23 |
20100240080 | KINASE AND PHOSPHATASE ASSAYS - Compositions, methods, and kits for detecting and monitoring kinase, phosphatase and protein post-translational modification activity are described. The compositions typically include a peptide, a detectable moiety, and a protease cleavage site. Modification of a peptide by a kinase, phosphatase or other protein post-translational modification alters the proteolytic sensitivity of the peptide, resulting in a change of a detectable property of the composition. Panel assays for determining substrates or modulators of kinase, phosphatase or other protein post-translational modification activity are also described. | 2010-09-23 |
20100240081 | SEPRASE AS A MARKER FOR CANCER - The present invention relates to a method aiding in the assessment of cancer. It discloses the use of the human fibroblast activation protein (FAP/seprase) as a universal marker of different cancer types. Seprase aids in the assessment of pulmonary or lung cancer (LC) or of colon cancer, e.g., of non-small cell lung carcinoma (NSCLC) or colorectal cancer (CRC), but also likely of other specific types of cancer. Such specific cancer types are, e.g., esophagus, head and neck cancer, stomach cancer, bile duct cancer, pancreas cancer, kidney cancer, cervix cancer, ovary cancer, breast cancer, bladder cancer, endometrium cancer or prostate cancer. Furthermore, it especially relates to a method for assessing cancer from a liquid sample, derived from an individual by measuring seprase in said sample. Measurement of seprase can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery. | 2010-09-23 |
20100240082 | METHODS FOR DETECTING AND MEASURING POLYSACCHARIDE-HYDROLYZING ENZYMES - Methods are disclosed for detecting and measuring polysaccharide-hydrolyzing enzyme activity or concentration by partial hydrolysis using a pre-determined, yet short, incubation time and a pre-determined temperature. The resulting reaction mixture has unique chemical (i.e., reaction products) and physical (i.e., viscosity) properties that can be used to detect or measure the polysaccharide-hydrolyzing enzyme activity or concentration. | 2010-09-23 |
20100240083 | METHOD FOR THE DETECTION OF THE IN-VIVO ACTIVITY OF NEUROTRYPSIN, USE OF THE METHOD AND USE OF THE C-TERMINAL, 22-KDA FRAGMENT OF AGRIN AS BIOMARKER IN DIAGNOSIS AND MONITORING OF NEUROTRYPSIN-RELATED DISTURBANCES - Method for the detection of the in-vivo activity of neurotrypsin wherein the amount of the 22-kDa-fragment of agrin is measured in a sample taken from a patient and the measured amount of the 22-kDa-fragment of agrin in the sample is used to calculate the activity of neurotrypsin, use of the method for diagnosis and monitoring of neurotrypsin-related disturbances and use of the 22-kDa-fragment of agrin as biomarker for neurotrypsin-related disturbances. | 2010-09-23 |
20100240084 | USE OF THE PROTIEN MABA (FABG1) OF MYCOBACTERIUM TUBERCULOSIS FOR DESIGNING AND SCREENING ANTIBIOTICS - The protein MabA, also named protein FabG1, which is recombinant in a purified form, or the recombinant proteins derived from the protein MabA by mutation of at least one amino acid. The uses of proteins MabA, or recombinant proteins derived from protein MabA by mutation of at lease one amino acid, proteins and to the crystalloghraphis co-ordinates thereof, in terms of the implementation of methods for designing and screening ligands of these proteins, and advantageously, ligands inhibiting the enzymatic activity of these proteins. | 2010-09-23 |
20100240085 | CONJUGATE MOLECULES - The present invention relates to compounds which are conjugates of two or more moieties capable of serving as substrates of an enzyme with peroxidase activity and one or more labels. The conjugate molecules of the invention are useful for detection of molecular targets, e.g. biological or chemical molecules, molecular structures, etc, in samples using a host of experimental schemes for detecting and visualizing such targets, e.g. immunohistochemistry (IHC), in situ hybridization (ISH), ELISA, Southern, Northern, and Western blotting, etc. The invention also relates to compositions comprising the conjugate molecules. | 2010-09-23 |
20100240086 | BIOCHIP ASSEMBLY AND ASSAY METHOD THEREOF - The present invention is directed to a biochip assembly comprising a semi-permeable membrane and an assay method using said biochip assembly for carrying out cell based assays. | 2010-09-23 |
20100240087 | METHOD AND SYSTEM FOR THE AUTOMATIC DETECTION AND DIAGNOSIS OF A CANCER STEM CELL - A method for predetermining whether a cancer has a probability to become metastatic or recurrent, having the steps of: obtaining a sample cell population; assaying the sample cell population; detecting the rate of change of the sample cell population's pH over time; and comparing the pH change versus a predetermined pH rate of change. Also provided is a method of treating a patient having the steps of: isolating a cancer stem cell from a patient; culturing the cancer stem cell to produce a pool of descendant cells; culturing cells from the pool of descendant cells in the presence at least one compound among: anti-cancer drugs, myeloablative, chemotherapeutic, and immunotherapeutic agents, and a combination thereof; assaying over time, during the step of culturing, hydrogen ion concentration in the set of cells; and selecting a candidate therapeutic regimen for the patient based on a result of the assaying step. | 2010-09-23 |
20100240088 | Peptide Markers for Diagnosis of Angiogenesis - The present invention relates to a method for detecting physiological or pathological blood vessel formation, preferably glioma activity, comprising determining the expression level of colligin 2 in blood, cerebrospinal fluid or tissue vasculature. The invention further relates to the use of a method for detecting physiological or pathological blood vessel formation wherein said use is for monitoring a disease process; a healing process; or a response to a disease therapy. | 2010-09-23 |
20100240089 | Lead isotope tracer method to determine bone mineral turnover - A method of determining bone mineral turnover in bone of a subject involves determining isotopic ratio of one lead isotope (preferably | 2010-09-23 |
20100240090 | METHODS AND PLATFORMS FOR DRUG DISCOVERY - The present invention involves methods for identifying an agent that corrects a phenotype associated with a health condition or a predisposition for a health condition. The invention also involves methods for identifying a diagnostic cellular phenotype, determining the risk of a health condition in a subject, methods for reducing the risk of drug toxicity in a human subject, and methods for identifying a candidate gene that contributes to a human disease. The invention also discloses human induced pluripotent stem cell lines. | 2010-09-23 |
20100240091 | BIOCHEMICAL TEST FOR CONFIRMING THE PRESENCE OF L. MONOCYTOGENES - The invention relates to a biochemical test for confirming the presence of | 2010-09-23 |
20100240092 | DETECTION METHOD AND DETECTION APPARATUS - Provided is a method of adjusting detection sensitivity in detecting a sample in a channel. A detection method of optically detecting a sample includes: forming a multilayer flow, in which at least one of layers of the multilayer flow contains the sample; introducing light into at least one of layers of the multilayer flow; and detecting a signal generated from the multilayer flow in response to the introduced light, to detect the sample. The sample includes one of a chemical substance, a molecule, a cell, a particle, and a mixture thereof. At least one of fluids included in the multilayer flow has a refractive index different from a refractive index of another one of the fluids. | 2010-09-23 |
20100240093 | Isolated Staphylococcus Pseudolugdunensis - Disclosed is an isolated strain of a previously unknown | 2010-09-23 |
20100240094 | FERMENTER FOR GENERATING BIOGAS FROM PUMPABLE ORGANIC MATERIAL - The invention relates to a fermenter for generating biogas from pumpable organic material with a low content of organic dry matter (oTS), comprising at least one inlet for the pumpable organic material, at least one fixed bed reactor for the pumpable organic material with at least one primary and one secondary section and at least one outlet the remaining fermentation residue. Furthermore, the fermenter can optionally comprises at least one sedimentation chamber for the pumpable organic material, arranged between the primary and secondary sections and at least one recycling section connected to the sedimentation chamber and designed such that specific lighter fractions of the pumpable organic material can be recovered and reintroduced to the rising (primary) section of the fixed bed reactor or a preceding or subsequent conventional fermenter. | 2010-09-23 |
20100240095 | Polypeptides having cellobiohydrolase II activity and polynuleotides encoding same - The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. | 2010-09-23 |
20100240096 | NOVEL HEMOPOIETIN RECEPTOR PROTEIN, NR10 - The inventors succeeded in isolating a novel hemopoietin receptor gene (NR10) using a sequence predicted from the extracted motif conserved in the amino acid sequences of known hemopoietin receptors. It was expected that two forms of NR10 exists, a transmembrane type and soluble form. Expression of the former type was detected in tissues containing hematopoietic cells. Thus, NR10 is a novel hemopoietin receptor molecule implicated in the regulation of the immune system and hematopoiesis in vivo. These novel receptors are useful in screening for novel hematopoietic factors capable of functionally binding to the receptor, or developing medicines to treat diseases related with the immune system or hematopoietic system. | 2010-09-23 |
20100240097 | MAMMALIAN EXPRESSION VECTOR WITH A HIGHLY EFFICIENT SECRETORY SIGNAL SEQUENCE - The present invention relates to a mammalian cell based expression and secretion system and the expression and secretion of recombinant proteins by using secretory signal peptides. The present invention also relates to an expression cassette useful for the secretion of a heterologous gene from a mammalian cell, in particular a CHO cell. The present invention is also directed to a method of secreting a heterologous protein from mammalian cells such as CHO cells. | 2010-09-23 |
20100240098 | PROCESS FOR PRODUCING MATURE RECOMBINANT MITE GROUP I ALLERGEN - The present invention relates to a process for producing mature recombinant Mite Group I allergen comprising the steps of a) providing an allergen expression system in the form of a host cell selected from the group of yeasts containing a vector comprising cDNA encoding pro-allergen, b) cultivating the allergen expression system at a cultivation pH of between 5.5 and 7.5 for a cultivation period to express pro-allergen to obtain a cultivation mixture containing pro-allergen, c) adjusting the pH of the cultivation mixture to a maturation pH of between 3.5 and 5.0, d) maintaining the cultivation mixture at the maturation pH for a maturation period to convert the pro-allergen into mature allergen to obtain a product mixture, and e) subjecting the product mixture to a purification method to isolate mature allergen from the product mixture. | 2010-09-23 |
20100240099 | rBSA from K. lactis Expression, Secretion and Purification of Recombinant Bovine Serum Albumin (rBSA) from K. lactis and uses thereof - A recombinant BSA (rBSA) that (a) substantially lacks deoxyribonuclease activity as determined by incubating rBSA with linear DNA overnight and gel electrophoresis, (b) lacks animal viruses associated with animal-derived cell growth supplements; and (c) is capable of stabilizing DNA proteins is provided. Methods for making the rBSA and using it to stabilize enzymes are also provided. | 2010-09-23 |
20100240100 | HUMAN ANTIBODIES THAT HAVE MN BINDING AND CELL ADHESION-NEUTRALIZING ACTIVITY - The invention is composed of monoclonal human MN antibodies or MN antibody fragments that target the GEEDLP repeat within the proteoglycan domain. The proteoglycan domain of the MN cell surface protein contains four of these identical GEEDLP repeats. Binding to the desired epitope is verified by competition ELISA, where ELISA signal can be attenuated by co-incubation with a peptide containing this repeat (PGEEDLPGEEDLP). This inhibition of binding can also be verified using Biacore assays, where binding of desired antibodies to immobilized MN or proteoglycan peptides can be inhibited by the peptide repeat. In addition to binding to the peptide repeat, human anti-MN antibodies can inhibit the cell adhesion of CGL-1 cells to MN coated plastic plates. Human anti-MN antibodies have been used to diagnose and quantify MN expression in cancer cells and tumors using FACS and immunohistochemical methods. An example is also provided where a human anti-MN IgG1 mediates tumor cell lysis though antibody-dependent cell-mediated cytotoxicity. Therefore, these antibodies will be useful for the treatment of cancers in which MN is upregulated or can be useful for the diagnosis of cancers in which MN is upregulated. | 2010-09-23 |
20100240101 | Parallel Proximity Ligation Event Analysis - The present invention describes compositions and methods showing that the spatial proximity of intracellular components may be related to their ability to cooperate in intracellular biochemical reactions. In some embodiments, the present invention contemplates a variety of nucleic acid barcoded binding partners capable of determining the spatial proximity of intracellular components as determined by ligation of their respective nucleotide barcodes. As such, an intracellular component contact map may be constructed to fingerprint specific physiological and/or pharmacological intracellular conditions. | 2010-09-23 |
20100240102 | METHODS AND COMPOSITIONS FOR MULTIPLE DISPLACEMENT AMPLIFICATION OF NUCLEIC ACIDS - Disclosed are methods for multiple displacement amplification of a nucleic acid sequence in a sample. The nucleic acid is contacted with a reaction mixture that includes a set of oligonucleotide primers and a plurality of polymerase enzymes. The reaction mixture is subjected to conditions under which the nucleic acid sequence is amplified to produce an amplification product in a multiple displacement amplification reaction. Also disclosed are kits containing a set of oligonucleotide primers with random sequences having lengths of 6 to 8 nucleobases. At least some of the individual members of the primers have one or more ribose modifications that stabilize or lock the ribose ring in a 3′ -endo conformation. At least some of the primers have one or more universal nucleobases. | 2010-09-23 |
20100240103 | OLIGONUCLEOTIDES LABELED WITH A PLURALITY OF FLUOROPHORES - An embodiment of the invention discloses new methods for designing labeled nucleic acid probes and primers by labeling oligonucleotides with a plurality of spectrally identical or similar dyes and optionally with one or more quencher dyes. Oligonucleotides labeled in accordance with some embodiments of the invention exhibit a detectable increase in signal, for example, fluorescent signal when the labeling dyes are separated from one another. Methods for separating the dye include cleaving the labeled oligonucleotides include using enzymes that have 5′-exonuclease activity. In one embodiment nucleic acid primers of the present invention may fluoresce upon hybridization to a target sequence and incorporation into the amplification product. Nucleic acid probes and primers of the present invention have wide applications ranging from general detection of a target nucleic acid sequence to clinical diagnostics. Major advantages of the oligonucleotides including nucleic acid probes and primers of many embodiments of the present invention are their synthetic simplicity, spectral versatility and superior fluorescent signal. | 2010-09-23 |
20100240104 | CONVERSION OF KNOT REJECTS FROM CHEMICAL PULPING - Knot rejects from chemical pulping processes are subjected to acid hydrolysis or an enzymatic hydrolysis treatment. The resultant hydrolysate is enriched with glucose, representing a value-added raw material for products using hexoses. The residue, separated from the said hydrolysate after the acid hydrolysis or enzyme treatment, consists of mainly knots or chips. The residue has a much improved aesthetic appearance which can be readily used as value-added raw materials for mulch or similar applications. The residue could also be extracted to obtain high value antioxidants and other nutraceutical chemicals such as lignans or can be utilized according to currently known practices including recooking, burning and depositing. | 2010-09-23 |
20100240105 | Method For Producing Glucosamine By Culturing Microorganism With Low-Cost Medium - A method for producing glucosamine with microorganism comprises of fermenting with a microorganism selected from the group consisting of | 2010-09-23 |
20100240106 | MUTANT ENZYMES - This invention relates to mutant enzymes with enhanced properties and processes for oxidation of organic compound substrates using such enzymes. | 2010-09-23 |
20100240107 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 2-ALKYL-1,1,3-TRIALKOXYCARBONYLPROPANE - A process for producing an optically active 2-alkyl-1,1,3-trialkoxycarbonylpropane (2), comprising a step of asymmetric hydrolysis of 2-alkyl-1,1,3-trialokoxycarbonylpropane (1) by using an enzyme capable of selectively hydrolyzing an ester moiety of either one enantiomer of 2-alkyl-1,1,3-trialkoxycarbonylpropane (1), or by using a culture of a microorganism capable of producing the enzyme or a treated object thereof. | 2010-09-23 |
20100240108 | SEQUESTRATION OF FORMALDEHYDE TO STABILIZE NITRILASE SPECIFIC ACTIVITY WHEN CONVERTING GLYCOLONITRILE TO GLYCOLIC ACID - A process is provided to improve the specific activity of an enzyme catalyst having nitrilase activity when converting glycolonitrile to glycolic acid under aqueous reaction conditions. Inclusion of an effective amount of at least one amine protectant improves the specific activity and catalytic productivity of the enzyme catalyst. | 2010-09-23 |
20100240109 | SEQUESTRATION OF FORMALDEHYDE TO STABILIZE NITRILASE SPECIFIC ACTIVITY WHEN CONVERTING GLYCOLONITRILE TO GLYCOLIC ACID - A process is provided to improve the specific activity of an enzyme catalyst having nitrilase activity when converting glycolonitrile to glycolic acid under aqueous reaction conditions. Inclusion of an effective amount of at least one amine protectant improves the specific activity and catalytic productivity of the enzyme catalyst. | 2010-09-23 |
20100240110 | SEQUESTRATION OF FORMALDEHYDE TO STABILIZE NITRILASE SPECIFIC ACTIVITY WHEN CONVERTING GLYCOLONITRILE TO GLYCOLIC ACID - A process is provided to improve the specific activity of an enzyme catalyst having nitrilase activity when converting glycolonitrile to glycolic acid under aqueous reaction conditions. Inclusion of an effective amount of at least one amine protectant improves the specific activity and catalytic productivity of the enzyme catalyst. | 2010-09-23 |
20100240111 | SEQUESTRATION OF FORMALDEHYDE TO STABILIZE NITRILASE SPECIFIC ACTIVITY WHEN CONVERTING GLYCOLONITRILE TO GLYCOLIC ACID - A process is provided to improve the specific activity of an enzyme catalyst having nitrilase activity when converting glycolonitrile to glycolic acid under aqueous reaction conditions. Inclusion of an effective amount of at least one amine protectant improves the specific activity and catalytic productivity of the enzyme catalyst. | 2010-09-23 |
20100240112 | Process for Preparing a Sugar Product - The invention relates to a method for producing sugars, such as glucose, by fractionating lignocellulose-containing biomass. The sugar product thus obtained is useful for the manufacture of bioethanol and other chemicals. | 2010-09-23 |
20100240113 | METHOD OF DEGUMMING JUTE FIBRES WITH COMPLEX ENZYME (1) - A method of degumming jute fibres with complex enzyme, wherein said complex enzyme comprises pectinase and laccase, wherein comprising the steps of: a. soaking the jute fibres in the water solution of said complex enzyme made from pectinase and laccase, wherein the weight proportion of said complex enzyme water solution and jute fibres ranges from 12:1 to 40:1; b. adjusting the PH value of said complex enzyme water solution to more than 5.0, but no more than 6.5, and adjusting the temperature of said complex enzyme water solution to 35° C.-65° C., then keeping said complex enzyme water solution with such temperature value for 20-120 minutes; c. adjusting the PH value of said complex enzyme water solution to 7.5-9.5, and adjusting the temperature of said complex enzyme water solution to 40° C.-70° C.; then, keeping said complex enzyme water solution with such temperature value for 20-120 minutes; d. conducting enzyme deactivation of the jute fibres processed with said complex enzyme. | 2010-09-23 |
20100240114 | BIOMASS PRODUCTION AND PROCESSING AND METHODS OF USE THEREOF - The present invention provides methods and systems for the production of macroalgae in a manner to provide a sustained, economical source of biomass that may be used in various end-use processes, including energy production. The invention provides specific combinations of macroalgae types, saltwater growth medium compositions, and open pond water containers that results in biomass production beyond what may occur naturally without the required manipulation. Specifically, macroalgae that produce an exoskeleton in the presence of brackish water (e.g., stoneworts) have been found to provide excellent biomass production under the conditions of the invention. | 2010-09-23 |
20100240115 | BIOANALYTICAL ASSAY - A nanoparticle having a detectable feature and whose diameter is less than 200 nm, and which is coated with multiple specific binding reactants such that the affinity constant of the nanoparticle towards an analyte exceeds that of free binding reactant towards the analyte and/or the association rate constant between the nanoparticle and the analyte exceeds the association rate constant between the free binding reactant and the analyte. Also disclosed is a homogenous assay based on a first group labeled with a luminescent energy donor nanoparticle and a second group labeled with an energy acceptor compound, where the donor has a long excited state lifetime, and the increase or decrease, respectively, in the energy transfer from the donor to the acceptor resulting from shortening or lengthening, respectively, of the distance between these groups, is measured. | 2010-09-23 |
20100240116 | LOVASTATIN ESTERASE ENZYME IMMOBILIZED ON SOLID SUPPORT, PROCESS FOR ENZYME IMMOBILIZATION, USE OF IMMOBILIZED ENZYME, BIOCATALYTIC FLOW REACTOR AND PROCESS FOR PREPARATION AND/OR PURIFICATION OF SIMVASTATIN - The invention relates to the lovastatin esterase enzyme immobilized on a solid support insoluble in water, the enzyme being covalently bound to a solid support activated with an at least difunctional coupling reagent, the immobilized lovastatin esterase exhibiting at least 5 times higher the hydrolytic activity towards lovastatin and salts thereof, in the presence of simvastatin and/or salts thereof, than towards simvastatin and salts thereof. The invention also relates to a process for immobilization of the lovastatin esterase enzyme on a solid support insoluble in water, and use of the enzyme immobilized on a solid support for preparation and/or isolation and/or purification of simvastatin, and also to a process for preparation and/or purification of simvastatin comprising treating the solution of the simvastatin salt containing residual content of the lovastatin salt with the lovastatin esterase enzyme until hydrolysing lovastatin to form the triol; separating the triol; and isolating simvastatin substantially free from lovastatin, wherein the solution of the simvastatin salt containing residual content of the lovastatin salt, is brought into a contact with the lovastatin esterase enzyme immobilized on a solid support insoluble in water. Also, the invention relates to a biocatalytic flow reactor with a bed, comprising a body ( | 2010-09-23 |
20100240117 | THREE DIMENSIONAL FABRICATION OF BIOCOMPATIBLE STRUCTURES IN ANATOMICAL SHAPES AND DIMENSIONS FOR TISSUE ENGINEERING AND ORGAN REPLACEMENT - Methods and apparatuses involving biocompatible structures for tissue engineering and organ replacement and, more specifically, biocompatible structures formed by three-dimensional fabrication, are described. In some embodiments, the biocompatible structures are scaffolds for cells that can be used as tissue engineering templates and/or as artificial organs. The structures may be three-dimensional and can mimic the shapes and dimensions of tissues and/or organs, including the microarchitecture and porosities of the tissues and organs. Pores in the structure may allow delivery of molecules across the structure, and may facilitate cell migration and/or generation of connective tissue between the structure and its host environment. Structures of the invention can be implanted into a mammal and/or may be used ex vivo as bioartificial assist devices. | 2010-09-23 |
20100240118 | COVER REMOVABLE DEVICE FOR CULTURE VESSEL AND CULTURE APPARATUS - A lid removable device includes a first transferring mechanism transferring a culture vessel in a horizontal direction, a second transferring mechanism raising or lowering the culture vessel, a lid removable plate having an insertion region into which a vessel body of the culture vessel is inserted and a lid placing part on which a lid of the culture vessel is placed, and a transporting control unit controlling the first transferring mechanism so that the vessel body is inserted into the insertion region when the lid is removed from the culture vessel and controlling the second transferring mechanism so that the vessel body is separated from the lid, and controlling the first transferring mechanism so that the vessel body is positioned below the insertion region when the lid is attached to the culture vessel and controlling the second transferring mechanism so that the vessel body is moved toward the lid. | 2010-09-23 |
20100240119 | MICROSEPARATION STRUCTURE AND DEVICES FORMED THEREWITH - A microseparation structure is provided that includes a top surface defining a first chamber. A second chamber is provided that is in fluid communication with the first chamber and characterized by a volume less than the volume of the first chamber. At least one hole extends in fluid communication with the second chamber to transmit fluids into a capillary draw void volume filled with a capillary draw-inducing agent such that liquid placed in the first chamber is drawn through the second chamber and through the hole to the capillary draw void volume filled with capillary draw-inducing agent. Particles of interest within the liquid are unable to pass into the hole and are therefore isolated within the second chamber. This structure is amenable to forming into a compact chromatographic filtration media made up of multiple such structures that is well suited for sealed testing for diseases such as malaria. | 2010-09-23 |
20100240120 | ANALYTICAL STRIP AND THE MANUFACTURING METHOD THEREOF - An analytical strip including a substrate and a channel structure is disclosed. A substrate has a flat surface and the channel is formed on the flat surface according to a predetermined pattern. The surface of channel structure is not lower than the surface of the substrate. The channel has a hollow-matrix conformation and the channel is more hydrophilic than the flat surface of the substrate is. The strip also contains a reaction material formed in the hollow-matrix. | 2010-09-23 |
20100240121 | Electrospun nanofibrous membrane assembly for use in capturing chemical and/or biological analytes - A membrane assembly adapted for use in capturing an analyte of interest, the membrane assembly comprising in one embodiment (a) an electrospun nanofibrous membrane, the electrospun nanofibrous membrane comprising a random mat of electrospun nanofibers, at least some of the electrospun nanofibers including one or more types of functional groups; and (b) at least one molecular recognition element immobilized on the random mat via a functional group, the molecular recognition element being adapted to selectively bind the analyte of interest. The membrane assembly may be incorporated into a sensor. | 2010-09-23 |
20100240122 | Spotter provided with spot pattern encryption function and detection device coping with spot pattern encryption - Plural probes spotted on a probe immobilization substrate are arranged such that the probes cannot be specified by a third party easily. When the plural probes are spotted on the probe immobilization substrate, a position where each probe is spotted is changed for each probe immobilization substrate to be prepared, whereby types of probes to be arranged in respective spot addresses are encrypted. The preset invention provides a spotter, a dispensing device to be used for the spotter, a probe immobilization substrate that is prepared using the spotter, and a detection device that decodes encrypted positions where the respective probes are spotted. | 2010-09-23 |
20100240123 | Apparatus, System and Method for Purifying Nucleic Acids - Methods and devices for isolating nucleic acids from a mixture containing such nucleic acids and extraneous matter are provided. In one embodiment, the method of the invention comprises passing the mixture through a glass frit under conditions effective to separate the nucleic acids from the extraneous matter. In a more specific embodiment, the glass frit is a sintered glass frit. | 2010-09-23 |
20100240124 | SAMPLE PROCESSING DEVICE COMPRESSION SYSTEMS AND METHODS - Sample processing systems and methods of using those systems for processing sample materials located in sample processing devices are disclosed. The sample processing systems include a rotating base plate on which the sample processing devices are located during operation of the systems. The systems also include a cover and compression structure designed to force a sample processing device towards the base plate. The preferred result is that the sample processing device is forced into contact with a thermal structure on the base plate. The systems and methods of the present invention may include one or more of the following features to enhance thermal coupling between the thermal structure and the sample processing device: a shaped transfer surface, magnetic compression structure, and floating or resiliently mounted thermal structure. The methods may preferably involve deformation of a portion of a sample processing device to conform to a shaped transfer surface. | 2010-09-23 |
20100240125 | BONE DELIVERY CONJUGATES AND METHOD OF USING SAME TO TARGET PROTEINS TO BONE - A bone delivery conjugate having a structure selected from the group consisting of: A) X-D | 2010-09-23 |
20100240126 | DEVELOPMENT OF UNIVERSAL CANCER DRUGS AND VACCINES - This invention generally relates to a design and method for developing novel anti-tumor/cancer drugs, vaccines and therapies, using microRNA (miRNA) and its shRNA homologues/derivatives. More particularly, the present invention relates to the use of a nucleic acid composition capable of expressing mir-302-like gene silencing effectors upon delivery into human cells and then silencing mir-302-targeted cell cycle regulators and oncogenes, resulting in an inhibitory effect on tumor/cancer cell growth and metastasis. Mir-302 is the most predominant miRNA found in human embryonic stem (hES) and induced pluripotent stem (iPS) cells, yet its function is unclear. The present invention establishes that in humans mir-302 concurrently suppressed both cyclin-E-CDK2 and cyclin-D-CDK4/6 pathways and eventually blocked over 70% of the G1-S transition. Simultaneously, mir-302 also silences BMI-1, a cancer stem cell marker, and subsequently promotes the tumor suppressor functions of p16Ink4a and p14/p19Arf in inhibiting CDK4/6-mediated cell proliferation. Therefore, the present invention for the first time reveals the tumor suppressor function of mir-302 in humans. This novel finding advances the design and method for developing new cancer drugs, vaccines and therapies directed against multiple kinds of human tumors and cancers, in particular including, but not limited, malignant skin, prostate, breast and liver cancers as well as various tumors. | 2010-09-23 |
20100240127 | Method of cryopreserving cells - A non-linear cooling cryopreservation method for improving cryopreservation protocols for cells that involves producing a simulation of cellular responses to a range of cooling parameters; determining optimal cooling parameters required to minimize cryoinjury to the cells using simulation of cellular responses and experimental results; and incorporating optimal parameters into the protocol. The simulation is based on mathematical models of cellular parameters. A non-linear cooling cryopreservation protocol for cryopreserving stem cells is also disclosed that does not require cryoprotectants. | 2010-09-23 |
20100240128 | Modified Gene Silencing - This invention relates to methods of controlling gene expression or gene suppression in eukaryotic cells. One aspect of this invention includes modifying the degree of silencing of a target gene by use of a modified suppression element. Another aspect includes providing a eukaryotic cell having a desired phenotype resulting from transcription in the eukaryotic cell of a modified suppression element. Also provided are transgenic eukaryotic cells, transgenic plant cells, plants, and seeds containing modified suppression elements, and useful derivatives of such transgenic plant cells, plants, or seeds, such as food or feed products. | 2010-09-23 |
20100240129 | Transfer of Molecules - The invention relates to liposomes, particularly, but not exclusively, to liposomes for introducing a molecule into a cell, and to processes for making and using liposomes. | 2010-09-23 |
20100240130 | Differentiation and Enrichment of Islet-like Cells from Human Pluripotent Stem Cells - Methods for differentiating human pluripotent stem cells into islet-like cells are provided. In certain embodiments, the methods utilize sequential culturing of the human pluripotent stem cells with certain factors to produce islet-like cells. In certain embodiments, the population of cells produced by the methods is further enriched for islet-like cells. | 2010-09-23 |
20100240131 | Method of modifying the genome of gram-positive bacteria by means of a novel conditionally negative dominant marker gene - The invention relates to a novel method for modifying the genome of Gram-positive bacteria, to these bacteria and to novel vectors. The invention particularly relates to a method for modifying | 2010-09-23 |
20100240132 | HIGHLY EFFICIENT METHODS FOR REPROGRAMMING DIFFERENTIATED CELLS AND FOR GENERATING ANIMALS AND EMBRYONIC STEM CELLS FROM REPROGRAMMED CELLS - The present invention relates generally to the field of somatic cell nuclear transfer (SCNT) and to the creation of cloned animals and cells. The disclosure relates to a method of cloning a mammal, obtaining pluripotent cells such as embryonic stem cells, or for reprogramming a mammalian cell using an oocyte and a fertilized embryo. | 2010-09-23 |
20100240133 | Compositions and Methods for Transposon Mutagenesis of Human Embryonic Stem Cells - PiggyBac transposons and transposases with enhanced transposition activity in cells are provided. Also provided are associated methods and kits for both introducing exogenous DNA inserts into the genomes of host cells as well as for the removal of the inserts from the host cell genomes. Cells obtained by use of the compositions, methods and kits are also provided. | 2010-09-23 |
20100240134 | Beverage testing device and method - The present invention is a testing device that comprises a plurality of indicated measurements printed onto a base or support material with inert ink. A reactive reagent is arranged above the indicated measurements and dissolves when introduced into a beverage according to the percentage of sugar present in the beverage. The visual indicator may be compared to a color chart to determine the amount of sugar present in the beverage. Otherwise, the testing device may indicate a numerical value of sugar content present in the tested beverage. | 2010-09-23 |
20100240135 | System and method for sour gas well testing - The invention provides a method of testing sour natural gas by a) removing H | 2010-09-23 |
20100240136 | APPARATUS AND METHOD FOR ASSAYING COAGULATION IN FLUID SAMPLES - This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate. | 2010-09-23 |
20100240137 | DERIVATIZATION-ENHANCED ANALYSIS OF AMINO ACIDS AND PEPTIDES - The present invention provides compositions and methods for enhanced detection and quantification of amino acids by derivatization. Also provided are compositions and methods for enhanced detection and quantification of peptides by derivatization. | 2010-09-23 |
20100240138 | DIAGNOSIS OF AGE-RELATED MACULAR DEGENERATION USING BIOMARKERS - The invention relates to proteins associated with age-related macular degeneration (AMD). These proteins, which are present in blood, are expressed in individuals with AMD at either elevated or reduced levels compared to healthy individuals. The invention provides methods for diagnosing AMD. The invention provides methods for assessing the efficacy of treatment of AMD. The invention provides methods for monitoring the progression of AMD. | 2010-09-23 |
20100240139 | FREE RADICAL INITIATOR AND METHOD FOR PEPTIDE SEQUENCING USING THE SAME - The present invention relates to a free radical initiator and a method for peptide sequencing using the same. Compared with diazo or peroxy functionalized precursors, the precursors using the present compounds are chemically more robust and can generate radical species by homolytic cleavage upon thermal activation, enabling sequencing of more various peptides. In addition, the present invention makes it feasible to sequence peptides carrying disulfide bonds. | 2010-09-23 |
20100240140 | ENERGETIC MATERIAL DETECTOR - A method of detecting energetic materials, such as explosives, includes energizing a sample area that contains particles of energetic materials. In the method, temperature characteristics from the sample area are monitored, and a temperature released from exothermic decomposition of the particles is detected. The method further includes analyzing the detected temperature to determine the presence of the exothermic compound which caused the decomposition. | 2010-09-23 |
20100240141 | APPARATUS AND METHOD FOR MEASURING CONCENTRATION OF CARBON DIOXIDE IN WATER - An apparatus for measuring the concentration of carbon dioxide in water that can correct a reduction in measurement accuracy based on deterioration of a pH indicator is provided. A carbon dioxide concentration measurement apparatus includes a deterioration determining section that measures a change rate ΔA | 2010-09-23 |
20100240142 | ANALYZING DEVICE AND ANALYZING METHOD USING SAME - A solution component | 2010-09-23 |
20100240143 | Fully integrated portable screening system - A fully integrated portable screening system includes a main housing and a contact pad. The contact pad is removably positioned in the main housing and covered by at least one sample sheet. The contact pad is preferably constituted by a cylindrical baton which carries a roll of sample collection sheets. A test subject interacts with the contact pad, leaving a trace sample on the sample collection sheet. The contact pad is then placed within the main housing and the trace sample is exposed to a test medium designed to interact with a specific analyte of interest potentially present in the trace sample. After exposure to the test medium, the sample sheet is subjected to a testing mechanism which exposes any interaction between the test medium and the analyte of interest to produce a test result. | 2010-09-23 |
20100240144 | IMPROVED SERRS SUBSTRATE - An improved SERRS substrate for use in an improved analyte detector is provided by depositing a Raman enhancing surface on, or within, a porous 3D support matrix made of a solid support material. The support material is arranged to have a Raman dye distributed within the volume and the response to illumination of the dye is enhanced as a result of the dye being distributed within the volume and proximate to the Raman enhancing surface, which is also distributed within the volume. | 2010-09-23 |
20100240145 | Novel hemopoietin receptor protein, NR10 - The inventors succeeded in isolating a novel hemopoietin receptor gene (NR10) using a sequence predicted from the extracted motif conserved in the amino acid sequences of known hemopoietin receptors. It was expected that two forms of NR10 exists, a transmembrane type and soluble form. Expression of the former type was detected in tissues containing hematopoietic cells. Thus, NR10 is a novel hemopoietin receptor molecule implicated in the regulation of the immune system and hematopoiesis in vivo. These novel receptors are useful in screening for novel hematopoietic factors capable of functionally binding to the receptor, or developing medicines to treat diseases related with the immune system or hematopoietic system. | 2010-09-23 |
20100240146 | FLUORESCENT PROTEIN PARTICLES - A fluorescent protein particle comprising: a particle forming component capable of forming or aggregating into a substantially insoluble protein particle when expressed by a cell; a fluorescent component; and a functional component capable of binding to, or being bound by, a target. | 2010-09-23 |
20100240147 | HIGH SENSITIVITY NANOTECHNOLOGY-BASED MULTIPLEXED BIOASSAY METHOD AND DEVICE - In a method and device for high sensitivity analysis of multiple bioassays plurality of nanoparticles (N) is dispersed in a fluid sample, at least one probe (C) of a first type having affinity for at least one analyte being attached to each nanoparticle; a plurality of probes of at least a second type having affinity for the analyte is attached to the internal surface (S) of the container; means are provided for detecting the signal generated by the adhesion of the nanoparticles to the internal surface of the reactor, brought about by the interaction of the analyte with the nanoparticle-bound probes and that of the analyte with the probes attached to the internal surface. The method and the device are particularly effective for detecting different genotypes of human papilloma virus (HPV). | 2010-09-23 |
20100240148 | Method and Kit for Measurement of Acrolein Adduct in Sample Utilizing Agglutination Reaction of Immunological Microparticle - A method for measuring an acrolein adduct present in a sample comprising the steps of: (a) mixing a sample containing the acrolein adduct with a solution comprising an immunoglobulin that specifically recognizes the acrolein adduct; (b) adding to the mixture obtained in the step (a), a solution comprising microparticles to which a substance that specifically binds to the immunoglobulin that specifically recognizes the acrolein adduct and a blocking agent have been bound, and mixing them; and (c) measuring an extent of an agglutination reaction of the microparticles in the mixture obtained in the step (b), wherein the extent of the agglutination reaction being decreased relative to an amount of the acrolein adduct in the sample. The method enables a measurement of an acrolein adduct without requiring a complex operation. | 2010-09-23 |
20100240149 | ELECTRONIC ANALYTE ASSAYING DEVICE - The invention is an electronically processed single-step test device for detecting the presence of a preselected analyte in a fluid. The device includes a hollow rectangular outer casing, disposed within co-joined upper and lower sections of the casing are assay material, an electronic processing system, and a LCD display. The LCD display is observable through a viewing window. The assay material is a sorptive material including a fluid sample application region in the form of a sample wick in fluid communication with a test strip. The test strip includes an analyte capture region adjacent to a light shield. The electronic processing system includes red and green LEDs which are alternately pulsed or energized over predetermined periods of time to determine if fluid test results show a marker or markers in the capture region indicative of the presence of a preselected analyte in the fluid. If so, Yes+ is displayed on the LCD. If not, No− is displayed on the LCD. | 2010-09-23 |
20100240150 | MEASURING REAGENT AND TURBIDIMETRIC IMMUNOASSAY AND SAMPLE ANALYSIS TOOL USING THE SAME - A measuring reagent is provided that allows the amounts of insoluble carrier particles and monoclonal antibodies to be reduced, can improve measurement sensitivity with respect to an object to be measured in a low concentration range, allows the object to be measured in a wide concentration range, and is used for a turbidimetric immunoassay applicable to a sample analysis tool such as a test piece. The measuring reagent includes two types of insoluble carrier particle groups that are different in mean particle size from each other. The insoluble carrier particles contained in one insoluble carrier particle group support polyclonal antibodies and monoclonal antibodies, and the insoluble carrier particles contained in the other insoluble carrier particle group support at least one of the polyclonal antibodies and the monoclonal antibodies. Preferably, the former is an insoluble carrier particle group with a small mean particle size and the latter is an insoluble carrier particle group with a large mean particle size. | 2010-09-23 |
20100240151 | Method of double patterning and etching magnetic tunnel junction structures for spin-transfer torque MRAM devices - A method for forming a MTJ in a STT-MRAM is disclosed in which the easy-axis CD is determined independently of the hard-axis CD. One approach involves two photolithography steps each followed by two plasma etch steps to form a post in a hard mask which is transferred through a MTJ stack of layers. The hard mask has an upper Ta layer with a thickness of 300 to 400 Angstroms and a lower NiCr layer less than 50 Angstroms thick. The upper Ta layer is etched with a fluorocarbon etch while lower NiCr layer and underlying MTJ layers are etched with a CH | 2010-09-23 |
20100240152 | Current-Confined Effect of Magnetic Nano-Current-Channel (NCC) for Magnetic Random Access Memory (MRAM) - One embodiment of the present invention includes a memory element having a composite free layer including a first free sub-layer formed on top of the bottom electrode, a nano-current-channel (NCC) layer formed on top of the first free sub-layer, and a second free sub-layer formed on top of the NCC layer, wherein when switching current is applied to the memory element, in a direction that is substantially perpendicular to the layers of the memory element, local magnetic moments of the NCC layer switch the state of the memory element. | 2010-09-23 |
20100240153 | MANUFACTURE METHOD FOR PHOTOVOLTAIC MODULE - The present invention is directed to permitting a wiring material to be reused in a repair work so as to achieve productivity improvement and cost reduction. For this purpose, the invention includes: a step of overlaying a conductive adhesive film and the wiring material on an electrode of a solar cell in this order and temporarily fixing the wiring material to the solar cell by pressure bonding the wiring material under first temperature condition and first pressurizing condition; an inspection step of inspecting the quality of the temporarily fixed solar cell; a step of removing a solar cell determined to be defective in the inspection step so as to replace the defective solar cell with a non-defective solar cell and temporarily fixing the wiring material to the non-defective solar cell by pressure bonding the wiring material with the conductive adhesive film interposed therebetween, under the first temperature condition and first pressurizing condition; and a fixing step in which the arrayed solar cells having the wiring materials temporarily fixed thereto and the wiring materials are fixed together by thermally setting the conductive adhesive film under second temperature condition to apply heat higher than the first temperature condition. | 2010-09-23 |
20100240154 | TEMPERATURE CONTROL DEVICE, TEMPERATURE CONTROL METHOD, AND SUBSTRATE PROCESSING APPARATUS - Provided is a temperature control device for controlling a temperature of a member to be exposed to plasma in a substrate processing apparatus. The substrate processing apparatus includes a mounting electrode for mounting a target substrate and a facing electrode positioned to face the mounting electrode, excites a processing gas supplied between the mounting electrode and the facing electrode into plasma, and performs a plasma process on the target substrate with the plasma. The temperature control device includes a heating layer configured to heat a heating target member, a heat insulating layer positioned in contact with an opposite surface to a heating layer's surface facing the heating target member, and a cooling layer positioned in contact with an opposite surface to a heat insulating layer's surface facing the heating layer. | 2010-09-23 |
20100240155 | Auto Feedback Apparatus for Laser Marking - A method of manufacturing integrated circuits includes measuring a reflectivity value of a wafer. An optimum energy level for laser marking the wafer is determined using the reflectivity value. A laser beam having the optimum energy level is then emitted to make laser marks on the wafer. | 2010-09-23 |
20100240156 | METHOD FOR PROVIDING A NON-VOLATILE MEMORY - Testing a non volatile memory by exposing the non volatile memory to particle radiation (e.g. xenon ions) to emulate memory cell damage due to data state changing events of a non volatile memory cell. After the exposing, the memory cells are subjected to tests and the results of the tests are used to develop reliability indications of the non volatile memory. Integrated circuits with non volatile memories of the same design are provided. Reliability representations of the integrated circuits can be made with respect to a number of data state charging events based on the exposure and subsequent tests. | 2010-09-23 |
20100240157 | DISPLAY DEVICE, MANUFACTURING METHOD THEREOF, AND TELEVISION RECEIVER - The present invention discloses a method for manufacturing a display device comprising the steps of forming a first film pattern using a photosensitive material over a substrate, forming a second film pattern in such a way that the first film pattern is exposed by being irradiated with a laser beam, modifying a surface of the second film pattern into a droplet-shedding surface, forming a source electrode and a drain electrode by discharging a conductive material to an outer edge of the droplet-shedding surface by a droplet-discharging method, and forming a semiconductor region, a gate-insulating film, and a gate electrode over the source electrode and the drain electrode. | 2010-09-23 |
20100240158 | LED LIGHTING WITH INTEGRATED HEAT SINK AND PROCESS FOR MANUFACTURING SAME - A method for manufacturing an LED lamp assembly includes anodizing at least a portion of a surface of an electrically and thermally conductive base, such as an aluminum or aluminum alloy base, so as to form an electrically insulating coating. The base may form a heat sink or be coupled to a heat sink. The anodized surface is chemically etched and circuit traces that include an LED landing are formed on the etched anodized surface. LEDs are electrically and mechanically attached to the LED landing by means of conductive metallic solder such that heat generated from the LED is transferred efficiently through the solder and LED landing to the base and heat sink through a metal-to-metal contact pathway. | 2010-09-23 |
20100240159 | MANUFACTURING METHOD OF SEMICONDUCTOR LASER ELEMENT - Starting point regions for cutting | 2010-09-23 |
20100240160 | METHOD OF MANUFACTURING DISPLAY DEVICE, DISPLAY DEVICE THEREFROM AND MANUFACTURING APPARATUS THEREFOR - A method of manufacturing a display device includes forming a thin film transistor on an insulating substrate, forming an electrode which is electrically connected with the thin film transistor, forming a wall which surrounds the electrode, supplying a first solvent to the electrode that is surrounded by the wall, and supplying ink which comprises an organic material and a second solvent to the electrode which has previously received the first solvent. Thus, the manufacturing method produces a display device which has a uniform organic layer. | 2010-09-23 |
20100240161 | Method for fabricating nitride semiconductor light-emitting device - A method for fabricating a nitride semiconductor light-emitting device includes the steps of creating a recessed region in a nitride semiconductor substrate having a nonpolar plane or a semipolar plane, and providing a nitride semiconductor thin film including an n-type nitride semiconductor thin film, an active layer and a p-type nitride semiconductor thin film on the nitride semiconductor substrate. The p-type nitride semiconductor thin film is grown at a growth temperature higher than or equal to 700° C. and lower than 900° C. | 2010-09-23 |