38th week of 2013 patent applcation highlights part 60 |
Patent application number | Title | Published |
20130245189 | VINYLOZY GROUP-CONTAINING VINYL POLYMER - A vinyloxy group-containing vinyl polymer, useful as a heat or light curing reactive prepolymer, containing at least a constituent unit expressed by the following formula (I): | 2013-09-19 |
20130245190 | AQUEOUS FLOOR POLISHING COMPOSITION - The present invention is the aqueous floor polishing composition which contains the polyoxyalkylene diester compound represented by the following general formula (1) and does not contain the phosphorus-containing plasticizer. R | 2013-09-19 |
20130245191 | PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET - The present invention provides a pressure-sensitive adhesive composition and a pressure-sensitive adhesive sheet comprising a layer formed from the said composition. The pressure-sensitive adhesive composition comprises, as a base polymer, a block copolymer of a mono-vinyl-substituted aromatic compound and a conjugated diene compound. The pressure-sensitive adhesive composition further comprises a tackifier resin (T | 2013-09-19 |
20130245192 | METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE RUBBER, MODIFIED CONJUGATED DIENE RUBBER, AND RUBBER COMPOSITION - This invention relates to a method for producing a modified conjugated diene rubber wherein the method involves: (a) a step in which a conjugated diene polymer having an alkali metal or alkaline earth metal active end and obtained by polymerizing a conjugated diene compound or by polymerizing a conjugated diene compound with an aromatic vinyl compounds is reacted with a first alkoxysilane compound which has an alkoxysilyl group having two or more alkoxy groups and has a group protected by a protecting group wherein deprotection is possible to obtain a modified conjugated-diene polymer having an alkoxysilyl group; and (b) a step in which the modified conjugated-diene polymer is reacted with a second alkoxysilane compound which has an alkoxysilyl group. | 2013-09-19 |
20130245193 | NOVEL THERMOPLASTIC COMPOSITE MATERIAL - The present invention relates to the field of thermoplastics, the synthesis thereof and the use thereof. It describes in particular the integration of light ash resulting from the combustion of waste from the paper-making industry into thermoplastic matrices. It describes in particular the manufacture and use of novel thermoplastic composite materials containing a thermoplastic resin and light ash resulting from the combustion of waste from the paper-making industry. The present invention also describes a novel filler material capable of being combines with a thermoplastic resin in the manufacture of a thermoplastic composite material. | 2013-09-19 |
20130245194 | MOISTURE CURABLE SILYLATED POLYMER COMPOSITIONS CONTAINING REACTIVE MODIFIERS - Moisture-curable resin compositions comprising (a) a moisture-curable polymer having at least one hydrolysable silyl group; (b) a reactive modifier; (c) a catalyst for catalyzing the reaction between the moisture-curable polymer (a) and reactive modifier (b) under curing conditions; and cured compositions produced by contacting such resin compositions with water are disclosed. The moisture-curable resin composition is useful in the production of adhesives, including hot melt adhesives, primers, sealants, and coatings. | 2013-09-19 |
20130245195 | ELASTIC MEMBER, PROCESS CARTRIDGE AND IMAGE FORMING APPARATUS - There is provided an elastic member including a surface resin layer including a crosslinked product of a dimethyl silicone compound having a reactive group and a fluoroalkyl compound having a reactive group. | 2013-09-19 |
20130245196 | RADIATION-CURABLE AQUEOUS DISPERSIONS - The invention relates to radiation-curable aqueous dispersions having mercapto groups, to processes for preparing them, and to their use. | 2013-09-19 |
20130245197 | Robust Resin For Solvent-Free Emulsification - A branched polyester suitable for use in solvent-free emulsification, the branched polyester having a first original weight average molecular weight before undergoing solvent-free emulsification and a second weight average molecular weight after undergoing solvent-free emulsification, wherein the branched polyester has a structure that limits degradation of the polyester during solvent-free emulsification to less than about 20 percent of the first original weight average molecular weight, wherein the branched polyester comprises a compound of the formula described. | 2013-09-19 |
20130245198 | PNEUMATIC TIRE - The present invention is directed to a pneumatic tire comprising at least one component, the at least one component comprising a rubber composition comprising:
| 2013-09-19 |
20130245199 | FUNCTIONALIZED ELASTOMER - The present invention is directed to a functionalized elastomer comprising: a polymeric backbone chain derived from a monomer comprising at least one conjugated diene monomer and optionally at least one vinyl aromatic monomer; and a functional group bonded to the backbone chain, the functional group comprising an oligopeptide or modified oligopeptide. | 2013-09-19 |
20130245200 | MODIFIED HYDROCARBYLPHENOL-ALDEHYDE RESINS FOR USE AS TACKIFIERS AND RUBBER COMPOSITIONS CONTAINING THEM - The invention relates to a modified hydrocarbylphenol-aldehyde resin prepared by reacting a hydrocarbylphenol-aldehyde resin with a primary or secondary amine and further with an epoxide. The invention also provides a process for preparing a modified, hydrocarbylphenol-aldehyde resin and a rubber composition containing such resin. | 2013-09-19 |
20130245201 | LLDPE-LDPE BLOWN FILM BLEND - The LLDPE-LDPE blown film blend is a blown film made from a mixture of unimodal hexene-LLDPE (also referred to as h-LLDPE) and LDPE having a blend ratio between 2%-10% of LDPE added to 98%-90% of h-LLDPE. This blend results in a TD (transverse direction) tear resistance increase by 100% for a composition of between 2%-10% of LDPE with LLDPE. Impact failure energy increases by 20% for the composition of 5% LDPE with 95% h-LLDPE. There is improvement in strength in the TD direction for the composition starting at 10% of LDPE with h-LLDPE. The toughness in the MD (machine direction) direction increases for the compositions of approximately 10% LDPE with h-LLDPE. Moreover, film production of a composition starting at approximately 10% of LDPE with LLDPE requires less energy. | 2013-09-19 |
20130245202 | SULFUR-MODIFIED CHLOROPRENE RUBBER, MOLDING THEREOF, AND PRODUCTION METHOD THEREFORE - Provided are a sulfur-modified chloroprene rubber with reduced exothermicity, a molding thereof, and a production method therefor. | 2013-09-19 |
20130245203 | Viscosity Breaking Process for Olefin Polymers - Disclosed is a method for viscosity breaking of a polypropylene polymer, a polypropylene copolymer or a polypropylene polymer blend, which process comprises adding a chain transfer agent and an initiator to a polypropylene polymer, polypropylene copolymer or polypropylene polymer blend and heating the resultant composition. The chain transfer agent has a Cs value of greater than or equal to about 0.04 as measured in ethylene polymerization at 130° C. The initiator is for example an organic or inorganic peroxide, a carbon based radical generator, a bis azo compound, a stable nitroxyl compound, a sterically hindered NO-acyl compound or a sterically hindered alkoxyamine compound. | 2013-09-19 |
20130245204 | NOVEL AGENTS FOR REWORKABLE EPOXY RESINS - Compounds of formula I, uses as crosslinking agents or curing agents thereof, and resins obtained by using the compounds as crosslinking agents. | 2013-09-19 |
20130245205 | METHOD FOR PRODUCING POLYBUTYLENE TEREPHTHALATE BASED RESIN COMPOSITION, AND POLYBUTYLENE TEREPHTHALATE-BASED RESIN COMPOSITION FOR MOLDING - Provided are: a method for producing a polybutylene terephthalate-based resin composition which is capable of providing a molded article obtained therefrom with excellent physical properties such as excellent mechanical strength, while stably maintaining high fluidity when melted; and a polybutylene terephthalate-based resin composition for molding. Specifically, after melting a mixture that contains (A) a polybutylene terephthalate resin and (B) a polyvalent hydroxyl group-containing compound, (C) a phosphorus compound is added thereto. It is preferable to use a glycerin fatty acid ester or an ether obtained by an addition reaction of an alkylene oxide to a diglycerin as (B) a polyvalent hydroxyl group-containing compound. | 2013-09-19 |
20130245206 | Bioabsorbable Polymeric Compositions and Medical Devices - The bioabsorbable polymers and compositions of the present invention may be formed into medical devices such as stents that can be crimped onto a catheter system for delivery into a blood vessel. The properties of the bioabsorbable polymers allow for both crimping and expansion of the stent. The crystal properties of the bioabsorbable polymers may change during crimping and/or expansion allowing for improved mechanical properties such as tensile strength and slower degradation kinetics. Typically, bioabsorbable polymers comprise aliphatic polyesters based on lactide backbone such as poly L-lactide, poly D-lactide, poly D,L-lactide, mesolactide, glycolides, lactones, as homopolymers or copolymers, as well as formed in copolymer moieties with co-monomers such as, trimethylene carbonate (TMC) or ε-caprolactone (ECL). | 2013-09-19 |
20130245207 | POLYMER ELECTROLYTE MEMBRANE - Disclosed are a multi-block copolymer, its producing method and an electrolyte membrane using the same. The multi-block copolymer includes a hydrophobic block having a plurality of repeating units represented as chemical formula 1; and a hydrophilic block having a plurality of repeating units represented as chemical formula 2. The multi-block copolymer is acidified, and can be used to an electrolyte membrane and a fuel cell. The use of the multi-block copolymer as an electrolyte membrane ensures excellent dimensional stability. | 2013-09-19 |
20130245208 | PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET - The present invention provides a pressure-sensitive adhesive composition comprising a base polymer and a tackifier resin. The base polymer is a block copolymer of a mono-vinyl-substituted aromatic compound and a conjugated diene compound. The tackifier resin comprises a low softening point resin having a softening point below 120° C. and a high softening point resin having a softening point of 120° C. or above. The high softening point resin comprises a terpene-phenol resin. | 2013-09-19 |
20130245209 | METHOD FOR ACTIVATION OF CHROMIUM CONTAINING CATALYST PRECURSOR FOR POLYMERIZATION AND THE RESULTING POLYMERIZATION CATALYST - Method for activation of chromium containing catalyst precursor for polymerization and improved polymerization catalyst resulting The instant invention relates to an activation of a polymerization catalyst precursor by heat treatment comprising a support material and a catalyst precursor deposited thereon in a fluidized bed activator and to the use of the activated polymerization catalyst in the manufacture of polyolefins. The Method is performed in a cylindrical activator ( | 2013-09-19 |
20130245210 | Dual Metallocene Catalyst Systems for Decreasing Melt Index and Increasing Polymer Production Rates - The present invention provides dual catalyst systems and polymerization processes employing these dual catalyst systems. The disclosed polymerization processes can produce olefin polymers at higher production rates, and these olefin polymers may have a higher molecular weight and/or a lower melt index. | 2013-09-19 |
20130245211 | ORGANIC SEMICONDUCTOR MATERIALS, PREPARATION METHODS AND APPLICATIONS THEREOF - Disclosed are organic semiconductor material having the general formula (I), Wherein R | 2013-09-19 |
20130245212 | PREPARATION OF A SOLID CATALYST SYSTEM - Process for the preparation of a solid catalyst system comprising the steps of generating an emulsion by dispersing a liquid clathrate in a solution wherein (i) the solution constitutes the continuous phase of the emulsion and (ii) the liquid clathrate constitutes in form of droplets the dispersed phase of the emulsion, solidifying said dispersed phase to convert said droplets to solid particles and optionally recovering said particles to obtain said catalyst system, wherein the liquid clathrate comprises a lattice being the reaction product of aluminoxane, an organometallic compound of a transition metal of Group 3 to 10 of the Periodic Table (IUPAC 2007) or of an actinide or lanthanide, and a further compound being effective to form with the aluminoxane and the organometallic compound the lattice, and a guest being an hydrocarbon compound, and the solution comprises a silicon fluid and a hydrocarbon solvent. | 2013-09-19 |
20130245213 | Catalysts For Producing Polyaplha-Olefins - This invention is directed to new mono-cyclopentadienyl (“mono-Cp”) metallocene catalyst compounds useful for producing high viscosity PAOs with narrow molecular weight distribution and good shear stability. Specifically, this invention relates to a group of bridged mono-Cp catalysts wherein, in an embodiment of the invention, the aromatic ring structure is substituted with: 1) at least one phenyl group, 2) at least one alkyl group, and 3) at least one other group, such as a hydrocarbyl group, a heteroatom, or a heteroatom-containing group. | 2013-09-19 |
20130245214 | ACTIVATING SUPPORTS - Activating supports may be suitably prepared by (a) combining (i) fluorine-containing compounds having a reactive group and (ii) an organometallic compound, (b) addition of a porous mineral oxide support material, (c) heating the functionalized support from step (b) under an inert gas and then under an atmosphere comprising oxygen, and (d) recovering the activating support. The preferred fluorine-containing compounds have the formula: R(Fn)-X wherein R is hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl or substituted heterohydrocarbyl with up to 20 non-hydrogen atoms, n is 1-41, X is OH, SH or NR′ | 2013-09-19 |
20130245215 | Catalyst Composition Having Improved Flow Characteristics and Methods of Making and Using the Same - Catalyst compositions for the polymerization of olefins having improved flowability properties are provided. | 2013-09-19 |
20130245216 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS - SET-LRP polymerization of acrylic monomers under acidic conditions is described. The source of the acidity may be the solvent (e.g., an acetic acid-containing solvent) or in the monomer content (e.g., acrylic acid or methacrylic acid, optionally in combination with other monomers such as methyl methacrylate). | 2013-09-19 |
20130245217 | PROCESS FOR THE PREPARATION OF DIENE POLYMERS OF STATISTICAL VINYLARENE-DIENE COPOLYMERS - A process for the preparation of diene polymers or vinylarene-diene statistical (random) copolymers which comprises the anionic (cp) polymerization, in hydrocarbon solvents, of at least one monomer of a conjugated diene, optionally in the presence of a vinyl aryl monomer, and using a compound belonging to the group of lithium alkyls as initiator, characterized in that the total lithium alkyl initiator is modified in situ by means of a reaction with a compound having general formula (I): R | 2013-09-19 |
20130245218 | PROCESS FOR MAKING A SOLID CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION AND COPOLYMERIZATION - The present invention relates to a process for preparing a solid catalyst component suitable for producing polyethylene and its copolymers, said process comprising the steps of: (a) contacting a dehydrated support having hydroxyl groups with a magnesium compound having the general formula MgR | 2013-09-19 |
20130245219 | IONOMERS AND IONICALLY CONDUCTIVE COMPOSITIONS - This invention relates to ionomers and to ionically conductive compositions formed therefrom. The ionomers comprise polymerized units of monomers A and monomers B, wherein monomers A are perfluoro dioxole or perfluoro dioxolane monomers, and the monomers B are functionalized perfluoro olefins having fluoroalkyl sulfonyl, fluoroalkyl sulfonate or fluoroalkyl sulfonic acid pendant groups, CF | 2013-09-19 |
20130245220 | POLYMERISATION CONTROL RPOCESS - The present invention relates to a process for maintaining a continuous gas-phase (co-) polymerisation of olefins in a large fluidised bed reactor in a homogeneous mode whilst operating at high space time yield and condensation rate in the presence of a polymerisation catalyst. | 2013-09-19 |
20130245221 | PROCESS FOR PREPARING ETHYLENE AND PROPYLENE - The present invention provides a process preparing ethylene and propylene, comprising the step of:
| 2013-09-19 |
20130245222 | MODIFIED ISOCYANATE COMPOSITIONS AND MEHTODS OF PREPARING THE SAME - Modified isocyanate compositions having improved properties are provided. The compositions may be formed from the reaction of a isocyanate component, which is a compound terminated with at least one isocyanate group, and an organic acid derivative having the formula (RO) | 2013-09-19 |
20130245223 | HIGH HEAT POLYETHERSULFONE COMPOSITIONS - High heat polyethersulfone compositions are provided which possess unexpectedly high glass transition temperatures. The polyethersulfone compositions comprise structural units derived from fluorenone bisphenols such as 9,9-bis(4-hydroxyphenyl)fluorene, and structural units derived from at least one biphenyl-bissulfone such as 4,4′-bis((4-chlorophenyl)sulfonyl)-1,1′-biphenyl. The novel polyethersulfone compositions may further comprise structural units derived from one or more biphenols such as 4,4′-biphenol, bisphenols such as BPA, or other electrophilic sulfone monomers, such as bis(4-chlorophenyl)sulfone. In one embodiment, the polyethersulfone composition of the present invention comprises structural groups derived exclusively from 9,9-bis(4-hydroxyphenyl)fluorene and 4,4′-bis((4-chlorophenyl)sulfonyl)-1,1′-biphenyl and exhibits a single glass transition of greater than 300° C. | 2013-09-19 |
20130245224 | AFFINITY CHROMATOGRAPHY MATRIX - The present invention relates to a method of separating one or more immunoglobulin containing proteins from a liquid. The method includes first contacting the liquid with a separation matrix comprising ligands immobilised to a support; allowing the immunoglobulin containing proteins to adsorb to the matrix by interaction with the ligands; followed by an optional step of washing the adsorbed immunoglobulin containing proteins; and recovering said immunoglobulin containing proteins by contacting the matrix with an eluent which releases the proteins. The method improves upon previous separation methods in that each of the ligands comprises one or more of a protein A domain (E, D, A, B, C), or protein Z, or a functional variant thereof, with at least one of the monomers having a substitution of the C-terminal most proline residue after the third alpha-helix. | 2013-09-19 |
20130245225 | POLYPEPTIDE SYNTHESIS FOR DRUG DELIVERY - The present invention provides improved methods for the synthesis of polypeptide or peptide-linked compounds via a NCA-based polymerization reaction that produces high product yields in much less time. Such improved methods are achieved by application of a higher temperature and/or reduced pressure to the reaction such that an NCA-containing monomer melts. | 2013-09-19 |
20130245226 | Antibodies To Non-Functional P2X7 Receptor - The present invention provides antibodies that specifically bind to P2X | 2013-09-19 |
20130245227 | METHODS OF ACTIVATING CLOSTRIDIAL TOXINS - The specification discloses modified Clostridial toxins comprising an exogenous Clostridial toxin di-chain loop protease cleavage site located within the di-chain loop region; polynucleotide molecules encoding such modified Clostridial toxins; method of producing such modified Clostridial toxins, method of activating such modified Clostridial toxins and methods of activating recombinantly-expressed Clostridial toxins. | 2013-09-19 |
20130245228 | Isolation, Cloning, Sequencing and Functional analysis of -casein promoter along with the regions of exon1, intron1 and exon2 using mammary gland derived cell line of Buffalo (Bubulus bubalis) - The present invention relates to a method of in vitro isolation of buffalo β-caesin promoter (buCSN2) along with the regions exon1, intron1 and exon2 from the genomic DNA in vitro ( | 2013-09-19 |
20130245229 | Neutralising Antibody Molecules Having Specificity for Human IL-17 - The invention relates to an antibody molecule having specificity for antigenic determinants of IL-17, therapeutic uses of the antibody molecule and methods for producing said antibody molecule. | 2013-09-19 |
20130245230 | Unnatural Reactive Amino Acid Genetic Code Additions - This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided. | 2013-09-19 |
20130245231 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DRY EYE - The invention relates to therapeutic compositions for the treatment of dry eye, more specifically to compositions comprising a TRPM8 receptor agonist ligand. Furthermore, the invention relates to therapeutic compositions for the treatment of epiphora, more specifically to compositions comprising a TRPM8 receptor antagonist. | 2013-09-19 |
20130245232 | HIGHLY EFFECTIVE ANTI-CADHERIN ANTIBODY FOR INDUCTION OF ANTIBODY-DEPENDENT CELLULAR CYTOTOXICITY IN VIVO - It is an object of the present invention to provide an anti-cadherin antibody having high antibody-dependent cellular cytotoxicity. The present invention provides an anti-cadherin antibody, which recognizes any one of an upstream region of EC1, a cadherin domain 4 (EC4) and a cadherin domain 5 (EC5), wherein an antibody-dependent cellular cytotoxicity at an antibody concentration of 1 μg/mL is 30% or more. | 2013-09-19 |
20130245233 | Multispecific Molecules - The present invention is directed to multi-specific/multivalent molecules of novel formats. The molecules with the formats of the present invention have desired yield and thermostability. The present invention also includes methods of producing and using the molecules described herein. | 2013-09-19 |
20130245234 | VMP-LIKE SEQUENCES OF PATHOGENIC BORRELIA - The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borreliae, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies. | 2013-09-19 |
20130245235 | ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9) - Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described. | 2013-09-19 |
20130245236 | ANTIBODIES TO THE CHEMOKINE RECEPTOR XCR1 - The present invention relates to an antibody binding to murine XCR1. Furthermore, the present invention relates to a nucleic acid molecule encoding for said antibody, a vector comprising said nucleic acid molecule and a host cell comprising said vector. The present invention further embraces a method for producing the antibody. Moreover, the present invention claims the use of the antibody and a kit for detecting murine XCR1 | 2013-09-19 |
20130245237 | Analysis of Ubiquitinated Polypeptides - The invention relates to antibody reagents that specifically bind to peptides carrying a ubiquitin remnant from a digested or chemically treated biological sample. The reagents allow the technician to identify ubiquitinated polypeptides as well as the sites of ubiquitination on them. The reagents are preferably employed in proteomic analysis | 2013-09-19 |
20130245238 | Fibronectin Binding Domains with Reduced Immunogenicity - Fibronectin type III ( | 2013-09-19 |
20130245239 | PROTEOGLYCAN-BONDED FIBER PRODUCT AND METHOD OF MANUFACTURING SAME - An objective is to provide fiber products having smooth texture and excellent softness, and in addition, excellent durability. A proteoglycan-bonded fiber product including a fiber to which a proteoglycan is covalently bonded is provided. | 2013-09-19 |
20130245240 | Bio-Hybrid Material, Production Method Therefor, and Stent - Provided is a bio-hybrid material that does not cause elution of nickel ions and has an excellent endothelialization ability, a production method therefor, and a stent. The bio-hybrid material ( | 2013-09-19 |
20130245241 | Risperidone Immunoassay - Novel conjugates and immunogens derived from risperidone and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of risperidone and paliperidone in biological fluids. | 2013-09-19 |
20130245242 | Laundry Care Compositions Containing Dyes - This application relates to laundry care compositions comprising thiophene azo carboxylate fabric shading dyes and methods of treating a textile comprising such laundry care compositions. | 2013-09-19 |
20130245243 | FUNCTIONAL LIGANDS TO TARGET MOLECULES - The present invention relates functional ligands to target molecules, particularly to functional nucleic acids and modifications thereof, and to methods for simultaneously generating, for example, numerous different functional biomolecules, particularly to methods for generating numerous different functional nucleic acids against multiple target molecules simultaneously. The present invention further relates to functional ligands which bind with affinity to target molecules. The present invention further relates to methods for generating, for example, functional biomolecules, particularly to functional nucleic acids, that bind with functional activity to another biomolecule, such as a receptor molecule. More than one or multiple targets as used herein may generally include different types of targets, and/or may also include a multitude of a singular type of targets at different conditions, such as, for example, temperature, pH, chemical environment, and/or any other appropriate conditions. | 2013-09-19 |
20130245244 | Antibodies and Immunotoxins that Target Human Glycoprotein NMB - The invention provides high affinity antibodies suitable for forming immunotoxins that inhibit the growth of cells expressing human glycoprotein NMB, including glioblastoma multiforme cells, anaplastic astrocytoma cells, anaplastic oligodendroglioma cells, oligodendroglioma cells, and melanoma cells. The antibodies may be formed in cells transformed with an isolated nucleic acid encoding a polypeptide comprising an antibody heavy chain variable region (“VH”) and an antibody light chain variable region (“VL”). Such nucleic acids are provided. | 2013-09-19 |
20130245245 | METHODS AND COMPOSITIONS FOR ISOLATING SMALL RNA MOLECULES - The present invention concerns the use of methods and compositions for the isolation of small RNA molecules (100 nucleotides or fewer), such as microRNA and siRNA molecules. Such molecules are routinely lost in commonly used isolation procedures and therefore the present invention allows for a much higher level of enrichment or isolation of these small RNA molecules. | 2013-09-19 |
20130245246 | POLYSACCHARIDES COMPRISING CARBOXYL FUNCTIONAL GROUPS SUBSTITUTED BY A HYDROPHOBIC ALCOHOL DERIVATIVE - A polysaccharide comprising carboxyl functional groups, at least one of which is substituted with at least one hydrophobic radical:
| 2013-09-19 |
20130245247 | MODIFIED POLYURONIC ACIDS AND SALTS THEREOF - The present invention relates to a modified polyuronic acid represented by the following general formula (1) or a salt thereof which is excellent in surface activity: wherein R | 2013-09-19 |
20130245248 | ACETYLATED CELLULOSE ETHER AND ARTICLES INCLUDING SAME - Provided are acetylated cellulose ether and an article including the same. The acetylated cellulose ether has a molecular weight of about 1,000 to about 1,000,000 Daltons, a contact angle of about 20 to about 45 degrees (°), and a tensile strength of about 50 to about 100 MPa. | 2013-09-19 |
20130245249 | Hydroxypropylmethylcellulose Having High Thermal Gel Strength, Method For Producing The Same And Food Comprising The Hydroxypropylmethylcellulose - Provided is hydroxypropylmethylcellulose having a high thermal gelation temperature and a high thermal gel strength and a method for producing the same and a food comprising the hydroxypropylmethylcellulose. More specifically, provided is hydroxypropylmethylcellulose having an average substitution degree of a methoxy group of 1.0 to 2.0 per glucose unit, an average substitution degree of a hydroxypropoxy group of 0.05 to 0.4 per glucose unit, and a A/B value of 0.305 or greater wherein A represents a substitution degree of a methoxy group directly substituted for a hydroxy group on carbon at position 6 in a glucose unit free from a hydroxypropoxy group-substituted hydroxy group, B represents a substitution degree of a methoxy group per glucose unit, and the A/B represents a value of A divided by B. | 2013-09-19 |
20130245250 | METHOD FOR PRODUCING L-FUCOSE - Method for producing L-fucose includes in a first aspect, a method for the preparation of L-fucose, wherein L-fucose precursors are produced from pectin and L-fucose is produced from the L-fucose precursors; in a second aspect, a method for the preparation of L-fucose from D-galacturonic acid or a salt thereof, wherein L-fucose precursors are produced from D-galacturonic acid of a salt thereof, and L-fucose is produced from the L-fucose precursors; and an L-fucose precursor as shown in Formula A, wherein R is a linear or branched chain saturated hydrocarbon group with 1-6 carbon atoms, such as methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, s-butyl, t-butyl, n-hexyl, etc., preferably a methyl group. | 2013-09-19 |
20130245251 | METHOD FOR ISOLATING DIETARY FIBER ARABINOGALACTAN AND ARABINOGALACTAN IN COMBINATION WITH FLAVONOID DIHYDROQUERCETIN (TAXIFOLIN) FROM CONIFER WOOD SPECIES OR HARDWOOD INCLUDING BUTT LOGS AND BARK - A method for isolating arabinogalactan and arabinogalactan with flavonoid dihydroquercetin (taxifolin) from wood, including butt logs and bark. The method includes extracting an extract from a combination of a polar solvent with wood particles and recovering the extract. The wood particles include at least one of i) a particle-reduced chip fraction obtained by subdividing the butt logs into chips, and ii) a dry cork fraction of the bark or a powdered bark obtained as a residue in finishing of mechanical wood products. The wood is a coniferous hardwood or a coniferous wood selected from the group consisting of a wood of a | 2013-09-19 |
20130245252 | SIMULTANEOUS HYDROLYSIS AND HYDROGENATION OF CELLULOSE - A process is disclosed for conversion of cellulose in an Ionic Liquid medium. The process is characterized in that a cellulose-containing feedstock and an Ionic Liquid are mixed at a temperature below 80 ° C. The mixture is heated to a conversion temperature in the range of 80 ° C. to 220 ° C. under a hydrogen atmosphere. The presence of hydrogen during the heating step significantly reduces the formation of degradation products. | 2013-09-19 |
20130245253 | Conjugated Neuroactive Steroid Compositions And Methods Of Use - The present disclosure provides modified neuroactive steroids. The modified neuroactive steroids may comprise, consist of, or consist essentially of a therapeutic agent and/or a modifying moiety. The modified neuroactive steroid can have modified characteristics as compared to native neuroactive steroids that do not include a modifying moiety and/or therapeutic agent. The modified neuroactive steroid may be, for example, modified pregnenolone, pregnenolone metabolites, allopregnanolone, and/or allopregnanolone metabolites. The modified neuroactive steroids can be used to treat, prevent and/or ameliorating a phenotypic state of interest in a subject. | 2013-09-19 |
20130245254 | METHODS OF SYNTHESIS AND PURIFICATION OF HETEROARYL COMPOUNDS - Provided herein are methods to prepare Heteroaryl Compounds having the following structure: | 2013-09-19 |
20130245255 | HETEROCYCLIC COMPOUNDS AND EXPANSION AGENTS FOR HEMATOPOIETIC STEM CELLS - An expansion agent for hematopoietic stem cells and/or hematopoietic progenitor cells useful for improvement in the efficiency of gene transfer into hematopoietic stem cells for gene therapy useful for treatment of various disorders is provided. | 2013-09-19 |
20130245256 | QUINAZOLINE ANALOGS AS RECEPTOR TYROSINE KINASE INHIBITORS - This invention provides quinazoline analogs of Formula I: | 2013-09-19 |
20130245257 | COMPOUND HAVING HETERO RING SKELETON, AND PROCESS FOR PRODUCING OPTICALLY ACTIVE COMPOUND USING THE AFOREMENTIONED COMPOUND AS ASYMMETRIC CATALYST - The invention provides a compound having a heterocyclic skeleton of formula (I): | 2013-09-19 |
20130245258 | Preparation Method of alpha-imatinib Mesylate - Disclosed is a preparation method of α-imatinib mesylate. The reaction temperature of the method is low and the yield of the crystal is improved. Furthermore, the method is applicable to the industrial production. | 2013-09-19 |
20130245259 | PROCESS FOR THE PREPARATION OF BOSENTAN MONOHYDRATE - The invention relates to improved processes for the preparation of bosentan monohydrate which provide higher yield and purity. | 2013-09-19 |
20130245260 | NEPRILYSIN INHIBITORS - In one aspect, the invention relates to compounds having the formula: | 2013-09-19 |
20130245261 | PROCESS FOR PREPARING PAN-CDK INHIBITORS OF THE FORMULA (I), AND INTERMEDIATES IN THE PREPARATION - The invention relates to a novel process for the preparation of pan-CDK inhibitors of the formula (I), and intermediates of the preparation. | 2013-09-19 |
20130245262 | PROCESS FOR THE PREPARATION OF PAZOPANIB USING NOVEL INTERMEDIATE - The present invention provides a commercially viable process for preparing pazopanib and its pharmaceutically acceptable acid addition salts thereof in high yields using novel intermediate. The present invention also provides a process for the purification of pazopanib hydrochloride. | 2013-09-19 |
20130245263 | PROCESS FOR THE PREPARATION OF PYRIMIDINE DERIVATIVES - A process for the preparation of 5-substituted 4-amino-2-methylpyrimidines of the formula | 2013-09-19 |
20130245264 | PYRAZINO[2,3-D]ISOXAZOLE DERIVATIVE - The object of the present invention is to provide a compound which is useful as a production intermediate of pyrazine carboxamide derivative such as 6-fluoro-3-hydroxy-2-pyrazine carboxamide. The present invention provides a pyrazino[2,3-d]isoxazole derivative represented by the formula (I): | 2013-09-19 |
20130245265 | Benzoic Acid, Benzoic Acid Derivatives and Heteroaryl Carboxylic Acid Conjugates of Hydrocodone, Prodrugs, Methods of Making and Use Thereof - The presently described technology provides compositions comprising aryl carboxylic acids chemically conjugated to hydrocodone (morphinan-6-one, 4,5-alpha-epoxy-3-methoxy-17-methyl) to form novel prodrugs/compositions of hydrocodone, including benzoates and heteroaryl carboxylic acids, which have a decreased potential for abuse of hydrocodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology. | 2013-09-19 |
20130245266 | SOLID FORMS AND PROCESS FOR PREPARING - The present invention provides amorphous solid forms of the compound of Formula I, as well as methods for preparing the compound of Formula I by precipitation. | 2013-09-19 |
20130245267 | NOVEL FORMS OF APIXABAN - The present application relate to amorphous form of Apixaban useful in making pharmaceutically acceptable dosage forms, and to processes for their preparation. | 2013-09-19 |
20130245268 | ENANTIOSELECTIVE ORGANIC ANHYDRIDE REACTIONS - Disclosed herein is enantioselective synthetic method comprising reacting an enolisable C | 2013-09-19 |
20130245269 | Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces - The present invention describes tripodal catechol derivatives with an adamantyl basic framework for the functionalisation of surfaces, methods for their production and use. The remaining fourth bridgehead position is easily suitable to be further functionalised via so-called click reactions, by way of example with biomolecules, dyes, radiomarkers, polyethylene glycol or active agents. | 2013-09-19 |
20130245270 | Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces - The present invention describes tripodal catechol derivatives with a flexible basic framework for the functionalisation of surfaces, and methods for their production and use. The central atom of the flexible framework is hereby a tertiary aliphatic carbon atom. The remaining fourth bridgehead position is easily suitable to be further functionalised via so-called click reactions, e.g. with biomolecules, dyes, radiomarkers, polyethylene glycol or active agents. | 2013-09-19 |
20130245271 | PROCESS FOR PRODUCING 4-CARBONYLOXYQUINOLINE DERIVATIVES - An objective of the present invention is to provide a process for producing 4-carbonyl oxyquinoline derivatives useful as agricultural and horticultural pesticides and fungicides. The objective can be attained by a process for producing 4-carbonyl oxyquinoline derivatives represented by general formula (1), the process including reacting a quinolone derivative with a halogenated compound or an acid anhydride in the presence of a phase transfer catalyst and a base. | 2013-09-19 |
20130245272 | PROCESS FOR CYCLOOXYGENASE-2 SELECTIVE INHIBITOR - The present invention describes a process for preparing a cyclooxygenase-2 selective inhibitor. It provides a synthetic procedure for the said substance namely 5-chloro-3-(4-methylsulphonyl)phenyl-2-(2-methyl-5-pyridinyl)pyridine of formula (I). The invention also relates to preparation of a new intermediate of formula (IV) and a process to prepare it. Furthermore, the invention describes a process for preparing another key intermediate of formula (II). Compounds of formula (IV) and formula (II) are useful intermediates in synthesis of the said cyclooxygenase-2 inhibitor. | 2013-09-19 |
20130245273 | AMINOPYRIDINES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention. | 2013-09-19 |
20130245274 | Process for the preparation of 3-(6-amino-pyridin-3yl)-2-acrylic acid derivatives - The present invention relates to a process for the preparation of a compound of the formula I, | 2013-09-19 |
20130245275 | PHENYL DIAMIDES AND A PHARMACEUTICAL PREPARATION COMPRISING PHENYL DIAMIDES - The present invention relates to phenyl diamides according to the general formula (1) and their use as a medicament and a pharmaceutical preparation comprising as an active ingredient a phenyl diamide according to the general formula (1). Further, the present invention relates to phenyl diamides according to the formulas (16), (17) and (18) for use in the treatment of gliomas. | 2013-09-19 |
20130245276 | PROCESS FOR HOMOGENEOUSLY CATALYZED, HIGHLY SELECTIVE DIRECT AMINATION OF PRIMARY ALCOHOLS WITH AMMONIA TO PRIMARY AMINES WITH A HIGH VOLUME RATIO OF LIQUID PHASE TO GAS PHASE AND/OR HIGH PRESSURES - The present invention relates to a process for preparing primary amines comprising the process steps
| 2013-09-19 |
20130245277 | NOVEL IRIDIUM CATALYST COMPLEXES AND C-H BOND ACTIVATED PRODUCTS THEREFROM - Provided is a novel iridium catalyst complex which is useful in the dehydrogenation of alkanes. The iridium complex comprises the metal iridium atom complexed with a benzimidazolyl-containing ligand. The iridium atom can be coordinated with the nitrogen atoms in the benzimidazolyl-containing ligand to form an NCN pincer ligand complex. In another embodiment, the iridium catalyst is used, with or without a co-catalyst, in a dehydrogenation reaction converting alkanes to olefins. The reaction can be in a closed or open system, and can be run in a liquid or gaseous phase. | 2013-09-19 |
20130245278 | PROCESS FOR THE PREPARATION OF FEBUXOSTAT - An improved and efficient process for the preparation of 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic acid (febuxostat) that is substantially free from amide by-product is provided. | 2013-09-19 |
20130245279 | PROCESSES FOR PREPARING BENZIMIDAZOLE COMPOUNDS - Provided are processes for the preparation of benzimidazole structures having Formula VIIIb-1: | 2013-09-19 |
20130245280 | AMINE COMPOUND AND USE FOR SAME - Provided is an ester of 3-[(4-dipropylamino-butyl)(4-{[(1H-imidazole-2-ylmethyl)(1-methyl-1H-imidazole-2-ylmethyl)amino]methyl}benzyl)amino]propionic acid which is easily hydrolyzed in serum. The amine compound of the present invention is an ester compound represented by general formula (1). (In general formula (1), n is 1-4, and R | 2013-09-19 |
20130245281 | PROCESSES FOR THE MANUFACTURE OF A PHARMACEUTICALLY ACTIVE AGENT - Disclosed herein are processes for the preparation of a pharmaceutically active agent and pharmaceutically acceptable salts thereof. | 2013-09-19 |
20130245282 | ORGANIC SEMICONDUCTOR THIN FILM, ORGANIC SEMICONDUCTOR DEVICE AND ORGANIC FIELD EFFECT TRANSISTOR - An organic semiconductor thin film including an organic semiconductor material that is easily synthesized, and is chemically and physically stable, and shows a high carrier mobility, an organic semiconductor device and an organic field effect transistor including the organic semiconductor thin film are provided. An organic semiconductor thin film of the invention includes a compound represented by the following formula 1: | 2013-09-19 |
20130245283 | THERAPEUTIC AND DELIVERY METHODS OF PROSTAGLANDIN EP4 AGONISTS - A compound comprising a prodrug of a prostaglandin EP | 2013-09-19 |
20130245284 | Prodrugs of Fluorinated Mevalonates to Inhibit the Mevalonate Pathway of Streptococcus pneumoniae - Fluorinated prodrug compounds as can be used for selective streptococcal mevalonate pathway inhibition. | 2013-09-19 |
20130245285 | New Process for Preparing Cyclolignans - The invention relates to a one-pot reaction for the preparation of a compound of Formula (I). The compound of Formula (I) may be further transformed into picropodophyllin and derivatives thereof. | 2013-09-19 |
20130245286 | PROCESS FOR PRODUCING WINE LACTONE - The present invention relates to a method comprising (A) reacting a β-keto ester with a 2-halo ester under basic conditions to obtain a 2-aceto-3-methyl-succinic acid ester; (B) reacting the resulting 2-aceto-3-methyl-succinic acid ester with methyl vinyl ketone under basic conditions, optionally followed by a decarboxylation reaction and hydrolysis, etc., to obtain an α-methyl-γ-keto acid; and (C) reducing the resulting α-methyl-γ-keto acid to obtain wine lactone or a stereoisomer thereof or a mixture thereof. Alternatively, the present invention relates to a method comprising step (A) as recited above; (B) reacting the resulting 2-aceto-3-methyl-succinic acid ester with methyl vinyl ketone under basic conditions, followed by decarboxylation reaction to obtain an α-methyl-γ-keto acid ester; and (E) reducing the resulting α-methyl-γ-keto acid ester in the presence of a ruthenium complex having a specific structure and in the presence of a hydrogen donor to obtain wine lactone or a stereoisomer thereof or a mixture thereof. | 2013-09-19 |
20130245287 | PROCESS FOR PRODUCING WINE LACTONE - The present invention relates to a method comprising (A) reacting a β-keto ester with a 2-halo ester under basic conditions to obtain a 2-aceto-3-methyl-succinic acid ester; (B) reacting the resulting 2-aceto-3-methyl-succinic acid ester with methyl vinyl ketone under basic conditions, optionally followed by a decarboxylation reaction and hydrolysis, etc., to obtain an α-methyl-γ-keto acid; and (C) reducing the resulting α-methyl-γ-keto acid to obtain wine lactone or a stereoisomer thereof or a mixture thereof. Alternatively, the present invention relates to a method comprising step (A) as recited above; (B) reacting the resulting 2-aceto-3-methyl-succinic acid ester with methyl vinyl ketone under basic conditions, followed by decarboxylation reaction to obtain an α-methyl-γ-keto acid ester; and (E) reducing the resulting α-methyl-γ-keto acid ester in the presence of a ruthenium complex having a specific structure and in the presence of a hydrogen donor to obtain wine lactone or a stereoisomer thereof or a mixture thereof. | 2013-09-19 |
20130245288 | ANTI-LEISHMANIAL COMPOUND AND ANTI-LEISHMANIAL DRUG - Provided is an anti-leishmanial compound represented by formula (1): | 2013-09-19 |