35th week of 2013 patent applcation highlights part 59 |
Patent application number | Title | Published |
20130225388 | Li2O-Al2O3-SiO2 CRYSTALLIZABLE GLASS AND Li2O-AI2O3-SiO2 CRYSTALLIZED GLASS OBTAINED BY CRYSTALLIZING SAME - Provided is a Li | 2013-08-29 |
20130225389 | BOROSILICATE GLASS COMPOSITION FOR PRODUCING GLASS TUBES AND ITS USE FOR PRODUCING GLASS TUBES AND AS OUTER TUBE FOR LAMPS - A glass composition and its use for producing glass tubes is provided. The glass tubes having the provided composition are particularly suitable for the outer tubes of fluorescent lamps in the case of which a phosphor layer is baked at temperatures of up to 700° C. The tubes composed of the glass of the provided composition have a lower tendency to deform or stick together when processed at high temperatures. To obtain the observed effects, the molar ratio of Na | 2013-08-29 |
20130225390 | HIGH STRAIN POINT ALUMINOSILICATE GLASSES - Described herein are alkali-free, boroalumino silicate glasses exhibiting desirable physical and chemical properties for use as substrates in flat panel display devices, such as, active matrix liquid crystal displays (AMLCDs) and active matrix organic light emitting diode displays (AMOLEDs). In accordance with certain of its aspects, the glasses possess good dimensional stability as a function of temperature. | 2013-08-29 |
20130225391 | INORGANIC FIBROUS MOLDED REFRACTORY ARTICLE, METHOD FOR PRODUCING INORGANIC FIBROUS MOLDED REFRACTORY ARTICLE, AND INORGANIC FIBROUS UNSHAPED REFRACTORY COMPOSITION - To provide a highly bio-soluble fibrous shaped refractory article which can develop desired heat resistance without containing ceramic fibers such as aluminum silicate fibers, alumina powder and silica powder and can be provided at a low production cost and a low product cost. | 2013-08-29 |
20130225392 | CORDIERITE CERAMIC, AND MEMBER FOR SEMICONDUCTOR MANUFACTURING DEVICES WHICH COMPRISES SAME - A cordierite ceramic contains a main component having a composition including Mg of 12.6% by mass or more and 14.0% by mass or less in terms of an oxide, Al of 33.4% by mass or more and 34.4% by mass or less in terms of an oxide and Si of 52.0% by mass or more and 53.6% by mass or less in terms of an oxide, an accessory component having any one of Y, Yb, Er, and Ce in an amount of 4.5% by mass or more and 15.0% by mass or less in terms of an oxide based on 100% by mass of the main component, wherein cordierite, disilicate and spinel are present as crystal phases, a coefficient of thermal expansion of −120 ppb/° C. to +120 ppb/° C., a four-point bending strength of 170 MPa or more, a low thermal expansion performance and an excellent mechanical strength. | 2013-08-29 |
20130225393 | PROCESS FOR THE REGENERATION OF A CATALYST - Process for the regeneration of an at least partially coked molecular sieve catalyst comprising introducing the at least partially coked catalyst into a regenerator; introducing into the regenerator an oxygen-containing gas to regenerate at least part of the at least partially coked catalyst, thereby producing a gaseous mixture and at least partially regenerated catalyst; separating at least partially regenerated catalyst and at least part of the gaseous mixture; and analysing the composition of the gaseous mixture to control the burning rate of the coke present on the at least partially coked catalyst in the regenerator by adjusting the mass flow rate of the oxygen-containing gas on the basis of the analysis of the gaseous mixture. | 2013-08-29 |
20130225394 | PROCESS FOR THE REGENERATION OF A CATALYST - Process for the regeneration of an at least partially coked molecular sieve catalyst comprising introducing the at least partially coked catalyst into a regenerator; introducing into the regenerator an oxygen-containing gas to regenerate at least part of the at least partially coked catalyst, thereby producing a gaseous mixture and at least partially regenerated catalyst; recovering part of the at least partially regenerated catalyst; analysing the at least partially regenerated catalyst to control the burning rate of the coke present on the at least partially coked catalyst in the regenerator by adjusting one or more conditions of the regeneration of the at least partially coked catalyst on the basis of the analysis of the at least partially regenerated catalyst; and separating at least partially regenerated catalyst and at least part of the gaseous mixture as obtained in step (b). | 2013-08-29 |
20130225395 | Surge Drum Mixing System - Systems and methods for storing and handling slurries are provided. The surge drum system for storing a slurry can include a storage vessel having a first end, a second end, and at least one wall surrounding an internal volume between the first and second ends. The system can also include a slurry inlet and a slurry outlet, both in fluid communication with the internal volume. A recirculation inlet can be in fluid communication with the internal volume at the first end of the storage vessel. The system can also include a pump having a suction line in fluid communication with the outlet. A discharge line of the pump can be in fluid communication with an outlet valve and a recirculation valve that can be in fluid communication with the recirculation inlet. | 2013-08-29 |
20130225396 | PROCESS FOR REGENERATING CATALYST IN A FLUID CATALYTIC CRACKING UNIT - One exemplary embodiment can be a process for regenerating catalyst in a fluid catalytic cracking unit. Generally, the process includes providing a feed to a riser of a reaction vessel, and providing a stream to a distributor positioned within a void proximate to an inlet receiving unregenerated catalyst in a regenerator. The feed can include at least one of a gas oil, a vacuum gas oil, an atmospheric gas oil, a coker gas oil, a hydrotreated gas oil, a hydrocracker unconverted oil, and an atmospheric residue | 2013-08-29 |
20130225397 | Binderless Molecular Sieve Catalyst and a Preparation Method Thereof - The present invention relate to a binderless molecular sieve catalyst and a process for preparing the same, which are mainly useful for solving the problems of the current catalysts, such as lower activity, less pore volume and worse diffusivity. The present invention relates to a novel binderless molecular sieve catalyst, comprising, based on the weight of the catalyst, 90-100 wt. % of a molecular sieve, 0-10 wt. % of a binder, and 0-10 wt. % of an anti-wear agent, wherein said catalyst has a pore volume of 0.1-0.5 ml/g, an average pore diameter of 50-100 nm, and a porosity of 20-40%; the anti-wear agent is selected from the rod or needle-like inorganic materials having a length/diameter ratio of 2-20. Said catalyst has the advantages of higher activity, greater pore volume, larger average pore diameter and porosity, and better diffusivity, and well solves said problems and can be used for the industrial preparation of binderless molecular sieve catalysts. | 2013-08-29 |
20130225398 | Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product - Disclosed herein are processes for preparing procatalyst compositions with an internal electron donor containing greater than 4.5 wt % of a compounded alkoxyalkyl ester. Also disclosed are catalyst compositions containing the procatalyst composition and polymers, i.e., propylene-based polymers, produced therefrom. The present procatalyst compositions improve catalyst selectivity, catalyst activity, procatalyst morphology and polymer particle morphology, and improve hydrogen response during olefin polymerization. | 2013-08-29 |
20130225399 | SUPPORTED CATALYST AND USE THEREOF FOR REFORMING OF STEAM AND HYDROCARBONS - A method of making a supported catalyst for reforming of steam and hydrocarbons and a steam-hydrocarbon reforming process using the supported catalyst. The supported catalyst is made from a mixture comprising 20 to 99.5 mass % of lanthanum-stabilized γ-alumina and/or lanthanum-stabilized θ-alumina, 0 to 60 mass % oalumina, 0 to 25 mass % of calcium carbonate and/or magnesium carbonate, and 0.5 to 5 mass % of graphite, a cellulose ether, and/or magnesium stearate. The supported catalyst has a porosity between 55% and 75% and a pore volume between 0.3 cc/g and 0.65 cc/g. | 2013-08-29 |
20130225400 | METHOD FOR PREPARING HYDROREFINING CATALYST - A method for preparing hydrorefining catalyst comprises the following steps: (1) mixing an aqueous ammonia solution with a polyamine complexing agent to form a mixed solvent; (2) adding a cobalt salt to the mixed solvent, dissolving the cobalt salt, and then adding a molybdenum salt and optional salts of other active components, and dissolving them to prepare an impregnating solution; and (3) impregnating a support with the impregnating solution, followed by aging, drying, and activating the impregnated support to form a hydrorefining catalyst. The hydrorefining catalyst prepared by this method has good activity, selectivity and stability in use. | 2013-08-29 |
20130225401 | Poly(Ionic Liquid) Sorbents and Membranes for CO2 Separation - Polymerizable ionic liquid monomers and their corresponding polymers (poly(ionic liquid)s) are created and found to exhibit high CO | 2013-08-29 |
20130225402 | REVERSIBLE THERMOSENSITIVE RECORDING MEDIUM - A reversible thermosensitive recording medium including an electronic information recording sheet having at least an electronic information recording element projecting from a surface thereof, a first sheet having a through hole into which the electronic information recording element can be inserted, and a second sheet having a cut-out portion capable of housing the entire electronic information recording sheet, wherein the second sheet houses in the cut-out portion the entire electronic information recording sheet, with being laid over the first sheet, and the electronic information recording element inserted into the through hole. | 2013-08-29 |
20130225403 | COMPOSITIONS FOR SEED TREATMENT - Described is a composition for seed treatment comprising a plant seed-binding protein, preferably an antigen-binding plant seed-binding protein. In one embodiment, the seed-binding protein is binding a polysaccharide, preferably pectin. Further described is the use of a plant seed-binding protein to bind a plant-enhancing agent to a plant seed, and to a method for treating plant seeds. | 2013-08-29 |
20130225404 | PESTICIDAL COMBINATIONS - The present invention relates to the composition comprising a neonicotinoid insecticide selected from: imidacloprid, clothianidin and thiamethoxam and a metabolic herbicide safener. The composition is of particular use in the treatment of plant propagation material (preferably seeds) and improves the growing characteristics of a plant and/or prevents from unwanted plant damage caused by herbicides. | 2013-08-29 |
20130225405 | Compositions Containing Identical Polyamine Salts of Mixed Anionic Pesticides - The present invention relates to a composition comprising a first salt, which contains a first anionic pesticide (A1) and a cationic polyamine (B), and a second salt, which contains a second anionic pesticide (A2) and a cationic polyamine (B), wherein both salts contain the same cationic polyamine (B), and wherein the cationic polyamine comprises at least two amino groups. It further relates to a method for preparing said comprising the step of contacting the first salt and the second salt. In addition, the invention relates to a method of combating harmful insects and/or phytopathogenic fungi, which comprises contacting plants, seed, soil or habitat of plants in or on which the harmful insects and/or phytopathogenic fungi are growing or may grow, plants, seed or soil to be protected from attack or infestation by said harmful insects and/or phytopathogenic fungi with an effective amount of said composition. It also relates to a method of controlling undesired vegetation, which comprises allowing a herbicidal effective amount of said composition to act on plants, their habitat or on seed of said plants. Finally, the invention relates to seed comprising said composition. | 2013-08-29 |
20130225406 | COMPOSITIONS FOR CONTROLLING THE PSYLLIDS TRIOZA ERYTREAE AND DIAPHORINA CITRI, VECTORS OF BACTERIA OF THE GENUS CANDIDATUS LIBERIBACTER, WHICH CAUSE THE MOST SERIOUS KNOWN DISEASE OF CITRUS, NAMELY HUANGLONGBING (HLB) - The present invention relates to the use of compositions that, when applied to citrus, are capable of controlling the psyllids | 2013-08-29 |
20130225407 | Glyphosate salt herbicidal composition - A process is provided for preparing a glyphosate salt solution that comprises potassium and IPA cations in a desired mole ratio, and that has a glyphosate a.e. concentration not less than about 400 g/l. The process includes adding glyphosate acid to a glyphosate potassium salt solution having a glyphosate assay of at least about 40% a.e. by weight, to form a slurry. The process also includes introducing isopropylamine, in an amount sufficient to neutralize the added glyphosate acid, to the slurry with mixing until all glyphosate is dissolved, to form a mixed glyphosate salt solution comprising potassium and IPA cations in the desired mole ratio. | 2013-08-29 |
20130225408 | FATTY AMINES, AMIDOAMINES, AND THEIR DERIVATIVES FROM NATURAL OIL METATHESIS - Fatty amine compositions made from a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives are disclosed. In another aspect, fatty amidoamines made by reacting a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives with an aminoalkyl-substituted tertiary amine are disclosed. The fatty amines or amidoamines are advantageously sulfonated, sulfitated, oxidized, or reduced. In other aspects, the ester derivative is a modified triglyceride made by self-metathesis of a natural oil or an unsaturated triglyceride made by cross-metathesis of a natural oil with an olefin. | 2013-08-29 |
20130225409 | QUATERNIZED FATTY AMINES, AMIDOAMINES AND THEIR DERIVATIVES FROM NATURAL OIL METATHESIS - Quaternary ammonium, betaine, or sulfobetaine compositions derived from fatty amines, wherein the fatty amine is made by reducing the amide reaction product of a metathesis-derived C | 2013-08-29 |
20130225410 | PLANT GROWTH REGULATION - The present invention relates to a method for improving the plant growth regulation of and/or enhancing crop plants, by applying to the plants a mixture of a plant growth regulator, and acibenzolar-S-methyl, and to a composition comprising the same. | 2013-08-29 |
20130225411 | PESTICIDAL COMPOSITIONS - A pesticidal composition comprising (a) a pesticidal effective amount of at least one compound of formula I in which Q is i or ii or iii or an agrochemically acceptable salt or an N-oxide thereof, and (b) a plant growth regulator, where the ratio of compound of formula I to plant growth regulator is from 20:1 to 1:25. | 2013-08-29 |
20130225412 | SILICON NANOCARRIER FOR DELIVERY OF DRUG, PESTICIDES AND HERBICIDES , AND FOR WASTE WATER TREATMENT - The various embodiments herein provide a nano silicon carrier as a drug delivery mechanism. The nano silicon carrier comprises a diatom frustules loaded with a drug molecule to be released at the target site. The diatom frustules are of | 2013-08-29 |
20130225413 | CYCLOPROPENE COMPOSITIONS - Stabilized liquid cyclopropene compositions are provided which comprise flowable, non-aqueous dispersion concentrates comprising a) a continuous substantially water-immiscible liquid phase and b) a dispersed solid phase comprising cured polymer particles prepared from a polymerizable thermoset resin which particles contain at least one cyclopropene complex, optionally a non-porous particulate mineral, and optionally a non-cross-linkable mobile chemical distributed therein, and wherein the outside surfaces of the particles comprise a colloidal solid material. The compositions of the invention can be used directly or with dilution to combat pests or as plant growth regulators. | 2013-08-29 |
20130225414 | TECHNIQUES FOR IMPROVING RELIABILITY OF A FAULT CURRENT LIMITING SYSTEM - Techniques for improving reliability of a superconducting fault current limiting system (SCFCL) are provided. In one particular exemplary embodiment, the techniques may be realized with a superconducting fault current limiting system (SCFCL) comprising: an input current lead and an output current lead, each current lead coupled to a power distribution/transmission network; a container; a superconductor contained in the container; a shunt disposed outside the container and in parallel with the superconductor; a cryogenic system configured to provide coolant into the container; and at least one sensor disposed near and configured to monitor at least one operating condition of at least one of the input current lead and the output current lead, the superconductor, and the shunt. | 2013-08-29 |
20130225415 | SUPERCONDUCTING ROTATING ELECTRICAL MACHINE AND MANUFACTURING METHOD FOR HIGH TEMPERATURE SUPERCONDUCTING FILM THEREOF - The present disclosure relates to a superconducting rotating electrical machine and a manufacturing method for a high temperature superconducting film thereof. The superconducting rotating electrical machine includes a stator, and a rotor rotatable with respect to the stator, the rotor having a rotary shaft and a rotor winding. Here, the rotor winding includes tubes disposed on a circumference of the rotary shaft and each forming a passage for a cooling fluid therein, superconducting wires accommodated within the tubes, and a cooling fluid flowing through the inside of the tubes. This configuration may allow for direct heat exchange between the superconducting wires and a refrigerant, resulting in improvement of heat exchange efficiencies of the superconducting wires. | 2013-08-29 |
20130225416 | ELECTRONIC SEQUENCING - A method for sequencing nucleic acid molecules a) amplifies nucleic acid molecules and b) sequences the amplified nucleic acid molecules. Steps (a) and (b) are carried out on an array of field effect transistor (FET) sensor elements, comprising an array of nanowires. Within the array, each FET may include at least one nanowire, or one each FETs can lie between two nanowires, or one nanowire of a nanowire pair is a nanowire FET, with nucleic acids bound to a nanowire surface. A chip includes one or more arrays of field effect transistor sensor elements. A kit for sequencing nucleic acid molecules, may include one or more amplifying reagents or sequencing reagents. | 2013-08-29 |
20130225417 | METHODS AND SYSTEMS FOR UNIVERSAL CARRIER SCREENING - Provided herein are methods, systems, and devices for genetic screening. The genetic screening of two or more individuals can be utilized to predict the phenotype of a child from the group of individuals. Also disclosed is prediction of a phenotype of a child from a subset of biological relatives, such as a potential mother and father, before conception. In many instances, the methods, systems and devices herein are utilized to predict the probability of a child developing a rare genetic disease. | 2013-08-29 |
20130225418 | LABELING AND SAMPLE PREPARATION FOR SEQUENCING - The invention provides methods for sequencing and sample preparation for sequencing and amplification. | 2013-08-29 |
20130225419 | Quantitative Total Definition of Biologically Active Sequence Elements and Positions - A library includes H unique nucleotide sequences involving every position along I continuous positions in a molecule. A method to prepare the library includes obtaining a microarray with a bound probe of up to J nucleotides, J=I+L, for H different probes. The first L nucleotides are reverse complementary to a constant portion in the library at a 5′ end. The remaining nucleotides of different probes are reverse complementary to corresponding different library members. A primer equal to the constant portion in the library is introduced. The primer is extended along the probe as a library strand using DNA polymerase. A first strand of a double stranded linker is ligated with a phosphate group to the library strand. The first strand has a sequence that matches a constant portion in the library at a 3′ end. The library strand is stripped from the probe and from a different second strand of the linker. | 2013-08-29 |
20130225420 | MOLECULAR SUBTYPING OF ORAL SQUAMOUS CELL CARCINOMA TO DISTINGUISH A SUBTYPE THAT IS UNLIKELY TO METASTASIZE - The present invention provides methods of analyzing a sample from a subject having oral epithelial dysplasia or oral SCC or suspected of having oral epithelial dysplasia or oral SCC. | 2013-08-29 |
20130225421 | NUCLEIC ACID AMPLIFICATION - In some embodiments, the present teachings provide methods for nucleic acid amplification, comprising forming a reaction mixture, and subjecting the reaction mixture to conditions suitable for nucleic acid amplification. In some embodiments, methods for nucleic acid amplification include subjecting the nucleic acid to be amplified to partially denaturing conditions. In some embodiments, methods for nucleic acid amplification include amplifying without fully denaturing the nucleic acid that is amplified. In some embodiments, the methods for nucleic acid amplification employ an enzyme that catalyzes homologous recombination and a polymerase. In some embodiments, methods for nucleic acid amplification can be conducted in a single reaction vessel. In some embodiments, methods for nucleic acid amplification can be conducted in a single continuous liquid phase of a reaction mixture, without need for compartmentalization of the reaction mixture or immobilization of reaction components. In some embodiments, methods for nucleic acid amplification comprise a amplifying at least one polynucleotide onto a surface under isothermal amplification conditions, optionally in the presence of a polymer. The polymer can include a sieving agent and/or a diffusion-reducing agent. | 2013-08-29 |
20130225422 | METHODS FOR ALLELE CALLING AND PLOIDY CALLING - Disclosed herein is a system and method for making allele calls, and for determining the ploidy state, in one or a small set of cells, or where a limited quantity of genetic data is available. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed and the haplotypes are determined using expected similarities between the target genome and the knowledge of the genomes of genetically related individuals. In one embodiment, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the genetic data from both parents, and possibly one or more sperm and/or sibling embryos. In another embodiment, the chromosome copy number can be determined using the same input data. In another embodiment, these determinations are made for embryo selection during IVF, for non-invasive prenatal diagnosis, or for making phenotypic predictions. | 2013-08-29 |
20130225423 | METHOD FOR ENRICHMENT AND ISOLATION OF ENDOGENOUS TRANSCRIPTION FACTOR AND COMPLEXES THEREOF AND CORRESPONDING TANDEM ARRAYS OF CONCATENATED TRANSCRIPTION FACTOR RESPONSE ELEMENTS - The present invention provides a method for enrichment and isolation of endogenous transcription factors and their complexes. Also, this invention provides corresponding tandem arrays of concatenated transcription factor response elements (catTFRE). The method employs the property of transcription factors binding to sequence-specific DNA elements during regulation of gene expression. The catTFREs are designed and synthesized as concatenate dual copies of DNA response elements for various transcription factors. The DNA sequence of synthesized catTFRE is cloned to a target vector. Biotinylated catTFRE with 200 bp arms is prepared by PCR strategy. For enrichment and isolation of endogenous transcription factors and their complexes, the biotinylated catTFRE is immobilized to streptavidin-coated magnetic beads and then incubated with nuclear extract. Thereby endogenous transcription factors and their complexes are isolated from nuclear extract. Identification by mass spectrometry or other functional characterization can be further performed according to the application purposes. | 2013-08-29 |
20130225424 | METHODS FOR DETERMINING RESPONSIVENESS TO A DRUG BASED UPON DETERMINATION OF RAS MUTATION AND/OR RAS AMPLIFICATION - The present disclosure provides methods for predicting the sensitivity (e.g., responsiveness) of a cell and/or biological sample obtained from a subject (e.g., a human) to a drug (e.g., a DHFR inhibitor). Such methods may comprise determining the presence or absence of one or more Ras mutations and/or determining the presence or absence of an amplification of the Ras gene in the cell and/or biological sample. The methods may be used to predict the responsiveness of a subject to treatment with a drug. | 2013-08-29 |
20130225425 | Modulation of NR2F6 and methods and uses thereof - The application provides methods of modulating NR2F6 in a cell or animal in need thereof by administering an effective amount of a NR2F6 modulator. | 2013-08-29 |
20130225426 | REACTIVITY-DEPENDENT AND INTERACTION-DEPENDENT PCR - Methods, reagents, compositions, and kits for reactivity-dependent polymerase chain reaction (RD-PCR) and interaction-dependent polymerase chain reaction (ID-PCR) are provided herein. RD-PCR is a technique useful for determining whether a reactive moiety can form a covalent bond to a target reactive moiety, for example, in screening a library of candidate reactive moieties for reactivity with a target reactive moiety, and in identifying an enzyme substrate, for example, in protease substrate profiling. ID-PCR is a technique useful for determining whether a ligand can non-covalently bind to a target molecule, for example, in screening a library of candidate ligands for non-covalent interaction with a target molecule. RD-PCR and ID-PCR are also useful in detecting the presence of an analyte or an environmental condition. | 2013-08-29 |
20130225427 | METHOD FOR PREDICTION OF RESPONSE TO IMMUNE MEDIATED DISEASE THERAPEUTICS - The present invention is based in part on the identification of a signature marker profile of immune variables to diagnose an immune mediated disease or for prediction of response to an immune mediated disease therapeutic agent. Additionally, the present invention provides methods for the prediction of response to an immune mediated disease therapeutic agent. | 2013-08-29 |
20130225428 | LIVER DISEASE MARKERS - New markers for diseased liver conditions have been identified. A combination of protein C (PROC) and retinol binding protein 4 (RBP4) in blood are biomarkers to distinguish patients at different stages of hepatic fibrosis due, for example, to chronic infection with hepatitis C virus (HCV). Also, alpha-1-B glycoprotein (A1BG), complement factor H (CFH) and insulin-like growth factor binding protein acid labile subunit (IGFALS) distinguish subjects with chronic or acute liver conditions such as hepatitis infection or liver fibrosis from healthy controls. | 2013-08-29 |
20130225429 | Method of Determining Thermodynamic and Kinetic Parameters from Measured Off Rates - A method for measuring a property of a binding interaction between a capture agent and a binding partner for the capture agent is provided. In certain embodiments, this method comprises: a) contacting a population of particles that are linked to a capture agent with a substrate comprising a binding partner to produce capture agent/binding partner complexes, wherein the population of particles comprises first particles that are bound to a single molecule of the capture agent and second particles that are bound to two molecules of the capture agent; b) applying a force to the bound support, wherein the force is in a direction that separates the particles from the support; and c) separately measuring the forces required to disassociate the first particles and the second particles from their respective complexes. | 2013-08-29 |
20130225430 | METHODS AND COMPOSITIONS FOR TREATMENT OF TOX-3 AND TFF-1 MEDIATED CANCER PATHOGENESIS - The present invention relates to biomarkers useful for the diagnosis, prognosis and treatment of cancer. In different embodiments, the invention relates to TOX3 and related biomarkers, such as TFF1, TFF3, AGR2, SCUBE2, CEACAM6, TSPAN1 or CXCR4. TOX3 and these related biomarkers are also useful for the characterization of different breast cancer disease subtypes. Also described herein are inventive compositions and methods drawn to the use of anti-TOX3 antibodies, inducible TOX3 transgenic animal models, TOX3 nucleic acids, peptides, and small molecules for detection and modulation of TOX3 function and/or expression. | 2013-08-29 |
20130225431 | ASSESSMENT OF CELLULAR FRAGMENTATION DYNAMICS FOR DETECTION OF HUMAN EMBRYONIC ANEUPLOIDY - Methods of evaluating the developmental potential of human embryos are disclosed. In particular, the invention relates to methods of detecting embryonic aneuploidy by assessment of cellular fragmentation dynamics in individual blastomeres of embryos up to the 4-cell stage. The methods of the invention should improve in vitro fertilization (IVF) outcomes by reducing inadvertent transfer of non-viable embryos likely to result in spontaneous miscarriage. | 2013-08-29 |
20130225432 | SOLUTION-BASED METHODS FOR RNA EXPRESSION PROFILING - The present invention is directed to novel high-throughput, low-cost, and flexible solution-based methods for RNA expression profiling, including expression of microRNAs and mRNAs. | 2013-08-29 |
20130225433 | PROSTATE CANCER MARKERS AND USES THEREOF - The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to mutations in cancer markers as diagnostic markers and clinical targets for prostate cancer. | 2013-08-29 |
20130225434 | COMPOSITIONS COMPRISING ENGINEERED PHOSPHOTHREONINE AFFINITY REAGENTS, METHODS OF MAKING, AND METHODS OF USE - This invention relates to the use of protein scaffolds for producing affinity reagents that are polypeptides that specifically bind to phosphopeptides. | 2013-08-29 |
20130225435 | METHODS AND SYSTEMS FOR ANALYSIS OF SINGLE CELLS - Methods are provided for diagnosis and prognosis of disease by analyzing expression of a set of genes obtained from single cell analysis. Classification allows optimization of treatment, and determination of whether on whether to proceed with a specific therapy, and how to optimize dose, choice of treatment, and the like. Single cell analysis also provides for the identification and development of therapies which target mutations and/or pathways in disease-state cells. | 2013-08-29 |
20130225436 | SPECIFIC ACTIVE SITE INHIBITORS OF ENZYMES AND METHODS OF PRODUCING SAME - The present disclosure provides a method of producing enzyme-specific inhibitors or substrate binding partners comprising: identifying active site residues of the substrate in the enzyme substrate complex or in substrate binding partner-substrate complex; randomizing the active site residues to produce a combinatorial library of substrate variants; and selecting substrate variants that inhibit enzyme activity or bind substrate as substrate-specific binding partners. The present disclosure also provides ubiquitin enzyme specific inhibitors and ubiquitin variants that bind ubiquitin interaction motifs. | 2013-08-29 |
20130225437 | BIOMARKERS OF CANCER - Disclosed is an IL-37 biomarker of cancer and methods of using the biomarker, including methods for diagnosis of cancer, methods of determining predisposition to cancer, methods of monitoring progression/regression of cancer, methods of assessing efficacy of compositions for treating cancer, as well as other methods based on the use of this cancer biomarker. | 2013-08-29 |
20130225438 | SOLUTION MICROARRAYS AND USES THEREOF - The present invention relates to solution microarrays. In particular, the present invention relates to an aqueous 2-phase system for solution microarrays and uses thereof. The present invention further relates to systems and methods for performing assays within the solution microarrays (e.g., diagnostic assays). | 2013-08-29 |
20130225439 | METHODS FOR IMPROVING INFLAMMATORY BOWEL DISEASE DIAGNOSIS - The present invention provides methods and systems to predict and diagnose inflammatory bowel disease (IBD) and subtypes such as ulcerative colitis (UC) and Crohn's disease (CD) by detecting the presence, absence, level, and/or genotype of one or more sero-genetic-inflammation markers. Advantageously, with the present invention, it is possible to provide a diagnosis of IBD versus non-IBD, to rule out IBD that is inconclusive for CD and UC, and to differentiate between CD and UC with increased accuracy. | 2013-08-29 |
20130225440 | Compositions and Methods Useful for the Treatment and Diagnosis of Inflammatory Bowel Disease - Compositions and methods useful for the diagnosis and treatment of IBD including Crohn's disease are disclosed. | 2013-08-29 |
20130225441 | INTEGRATED SEMICONDUCTOR BIOARRAY - A biosensor array, system and method for affinity based assays that are able to simultaneously obtain high quality measurements of the binding characteristics of multiple analytes, and that are able to determine the amounts of those analytes in solution. The invention also provides a fully integrated bioarray for detecting real-time characteristics of affinity based assays. | 2013-08-29 |
20130225442 | Lung Cancer Tests - Methods for the diagnosis of lung cancer and more specifically, non-small cell lung cancer are described. An assortment of biomarkers with diagnostic or prognostic value for non-small cell lung cancer (NSCLC) are used to establish a multi-analyte serum test capable of diagnosing patients with lung cancer. A first method assesses an elevated level of expression of one or more nucleic acids, a polypeptide encoded by the nucleic acid or an autoantibody to said polypeptide. An alternative method includes (a) determining whether or not a patient has NSCLC versus a non-NSCLC lung cancer, and (b) classifying the patient as susceptible to specific treatments if the patient has a NSCLC profile and classifying the patient as not susceptible to a specific treatment if the patient does not have a NSCLC profile. | 2013-08-29 |
20130225443 | METHOD OF EXAMINING POLYCYSTIC KIDNEY DISEASE AND METHOD OF SCREENING FOR THERAPEUTIC AGENT OF THE DISEASE - The present invention provides a method of examining polycystic kidney disease or a complication of polycystic kidney disease using a gene(s) selected from the group consisting of NTNG1, POSTN, TNC, KAL1, BST1, ACAT2, INSIG1, SCD, HSD3B1, KRT7, USP40, SULT1E1, BMP6, CD274, CTGF, E2F7, EDN1, FAM43A, FRMD3, MMP10, MYEOV, NR2F1, NRCAM, PDCK1, PLXNA2, SLC30A3, SNAI1, SPOCD1, MMP1, TFPI2, HMGA2, KRTAP4-7, KRTAP4-8, KRTAP4-9, MYPN, RPPH1, and SIAE, and a method of screening for a therapeutic agent or a preventive agent therefore, and further vascular endothelial cells or vascular mural cells obtained via differentiation induction from iPS cells formed from a somatic cell of a subject suffered from polycystic kidney disease and having cerebral aneurysm as a complication. | 2013-08-29 |
20130225444 | HIGH-THROUGHPUT CELL TRANSFECTION DEVICE AND METHODS OF USING THEREOF - Transfecting biology cells with nucleic acid molecules (DNA, siRNA) is an essential prerequisite in elucidating how genes function in complex cellular context and how their activities could be modulated for therapeutic intervention. Traditionally studies are carried out on a low throughput gene-by-gene scale, which has created a huge bottleneck in functional genomic study and drug discovery. Development of high-throughput cell transfection technology will permit functional analysis of massive number of genes and how their activities could be modulated by chemical or biological entities inside cells. This invention describes design, construction of device and apparatus for high throughput effective cell transfection. Procedures and protocols for using the device and apparatus are also described in the application. Novel methods of using the device in cell-based assays are also disclosed. | 2013-08-29 |
20130225445 | BIO-REACTION DEVICE CHIP - Provided is a bio-reaction device chip for confirming or detecting a biomaterial reaction, and more particularly, is a bio-reaction device chip, where a plurality of wells are formed in the plate to contain biomaterials to be tested, thereby simultaneously analyzing various targets, and the well is formed to have a structure of two or more steps such that the sample to be tested is contained in the lower well and a protective layer for protecting the sample, such as oil, is contained in the upper well, thereby preventing evaporation of the sample due to heating at the time of the biomaterial reaction, and thus, improving reliability in analysis. | 2013-08-29 |
20130225446 | RNA-MEDIATED GENE ASSEMBLY FROM DNA OLIGONUCLEOTIDES - The present invention is directed to methods and materials for RNA-mediated gene assembly from oligonucleotide sequences. In some embodiments, the oligonucleotides used for gene assembly are provided in an array format. An RNA polymerase promoter is appended to surface-bound oligonucleotides and a plurality of RNA copies of each oligonucleotide are then produced with an RNA polymerase. These RNA molecules self-assemble into a desired full-length RNA transcript by hybridization and ligation. The resulting RNA transcript may then be converted into double strand DNA useful in a variety of applications including protein expression. | 2013-08-29 |
20130225447 | siRNA Targeting Apolipoprotein B (APOB) - Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for APOB. | 2013-08-29 |
20130225448 | LATERAL FLOW ASSAYS USING TWO DIMENSIONAL FEATURES - The present invention relates to novel lateral flow devices using two dimensional features, preferably, uniform two dimensional test and control features, and the methods for detecting an analyte using the lateral flow devices, and processes for making the lateral flow devices. | 2013-08-29 |
20130225449 | LATERAL FLOW ASSAYS USING TWO DIMENSIONAL FEATURES - The present invention relates to novel lateral flow devices using two dimensional features, preferably, uniform two dimensional test and control features, and the methods for detecting an analyte using the lateral flow devices, and processes for making the lateral flow devices. | 2013-08-29 |
20130225450 | Method of Ligating a Nucleic Acid - A method of preparing a nucleic acid library in droplets in contact with oil, including: (a) blunt-ending nucleic acid fragments in a droplet in the oil to yield blunt-ended nucleic acid fragments;
| 2013-08-29 |
20130225451 | MATERIALS AND METHODS FOR THE SYNTHESIS OF ERROR-MINIMIZED NUCLEIC ACID MOLECULES - The present invention provides materials and methods useful for error correction of nucleic acid molecules. In one embodiment of the invention, a first plurality of double-stranded nucleic acid molecules having a nucleotide mismatch are fragmented by exposure to a molecule having unidirectional mismatch endonuclease activity. The nucleic acid molecules are cut at the mismatch site or near the mismatch site, leaving a double-stranded nucleic acid molecule having a mismatch at the end or near end of the molecule. The nucleic acid molecule is then exposed to a molecule having unidirectional exonuclease activity to remove the mismatched nucleotide. The missing nucleotides can then be filled in by the action of, e.g., a molecule having DNA polymerase activity. The result is double-stranded nucleic acid molecules with a decreased frequency of nucleotide mismatches. Also provided are novel nucleic acid sequences encoding mismatch endonucleases, polypeptides encoded thereby, as well as nucleic acid constructs, transgenic cells, and various compositions thereof. | 2013-08-29 |
20130225452 | Method of Preparing a Nucleic Acid Library - A method of preparing a nucleic acid library in droplets in contact with oil, including: (a) blunt-ending nucleic acid fragments in a droplet in the oil to yield blunt-ended nucleic acid fragments; | 2013-08-29 |
20130225453 | BIOMATERIAL DETECTING DEVICE - Provided is a biomaterial detecting device for confirming or detecting a biomaterial reaction, and more particularly to a biomaterial detecting device, which is formed in a stick type to thereby be immersed in a tube containing a biomaterial solution to be tested; has an upper portion with a cap structure to thereby induce reaction with a biomaterial, and thus facilitate confirmation and detection of the biomaterial; and is formed in a cap structure to thereby prevent evaporation of a sample and infiltration of an external material at the time of a biomaterial reaction in the tube, and thus improve reliability in analysis. | 2013-08-29 |
20130225454 | PETROLEUM ASHPHALTENE HANDLER ADDITIVE COMPOUND - This invention refers to the manufacture and use of a petroleum asphaltene handler additive compound, which when applied in heavy oil, it makes asphaltenes to remain in suspension or dissolve, producing a viscosity reduction effect, this way avoiding formation of asphaltenic conglomerates precipitation in oil wells, storage tanks, as well as keeping pipelines from being obstructed. | 2013-08-29 |
20130225455 | FLUID COMPOSITION COMPRISING GLASS MICROSPHERES AND METHOD OF MAKING AND USING THE SAME - There is provided aqueous fluids comprising a mixture of at least two polysaccharides, water, and glass microspheres having pacified surfaces. There is also provided a method for making a fluid the method comprising (a) selecting a plurality of glass microspheres having alkaline surfaces; (b) coating the surfaces of the plurality of glass microspheres with an acid; and (c) combining the coated glass microspheres with (i) a mixture comprising at least two cross-linkable polysaccharides, and (ii) water. The fluids are useful, for example, as a drilling fluid. | 2013-08-29 |
20130225456 | Biocide Compositions Comprising Quaternary Ammonium and Urea and Methods for Their Use - Composition and method for treating and/or preventing biological contamination using a biocide composition comprising at least one quaternary ammonium compound and urea. The method includes drying urea, and thereafter combining at least one quaternary ammonium compound and urea and may produce a potent biocide composition that is stable and able to chemically treat biological contamination in a variety of difficult to reach locations. Uses of the composition are also described. | 2013-08-29 |
20130225457 | DRILLING FLUID AND METHOD FOR DRILLING IN COAL-CONTAINING FORMATIONS - A drilling fluid and method for drilling in a coal containing formation. The method includes: providing a mixed metal-viscosified drilling fluid including at least 1% potassium salt; circulating the drilling fluid through the well; and drilling into a coal seam. | 2013-08-29 |
20130225458 | HYDROPHOBIC PROPPANT AND PREPARATION METHOD THEREOF - The invention discloses a hydrophobic proppant and a preparation method thereof. The aggregate particles of the hydrophobic proppant are coated with a coating resin which comprises a hydrophobic resin and nano-particles which are uniformly distributed in the coating resin and constitute 5-60% of the coating resin by weight. The contact angle labeled as θ between water and the hydrophobic proppant in which nano-particles are added is in the range of 120°≦θ≦180°. The proppant of the present invention is prepared by adding the nano-particles in the existing resin in which low-surface-energy substances with hydrophobic groups are added, and a rough surface with a micro-nano structure is constructed on the outer surface of the prepared resin film, so that the contact angle θ at the solid-liquid contact surface on the outer surface of the coating resin of the proppant is more than 120°. | 2013-08-29 |
20130225459 | LOW VISCOSITY OLIGOMER OIL PRODUCT, PROCESS AND COMPOSITION - The present invention relates to a low viscosity lubricant process, product, and composition characterized by low Noack volatility, low pour point, useful low temperature viscometrics, and high viscosity index and more particularly concerns a PAO composition having a kinetic viscosity at 100° C. in the range of about 4 cSt. | 2013-08-29 |
20130225460 | PHYSICO-CHEMICAL AND USAGE PROPERTIES OF AN EXISTING LUBRICANT - This invention provides a method for improving the physico-chemical and usage properties of an existing lubricant, of a solid or liquid consistency, such as gear oils, engine oils and all-purpose oils. The method is based on complementing the composition of the existing lubricant with a mixture of several solid substances (thickeners), in an amount varying from 5 to 35 weight percent of the initial existing lubricant. As a result of their addition, a considerable improvement in a number of the lubricant's properties is achieved. For example, an increase in saturation load, as measured on a 4-ball apparatus of 1600 N to 3150 N; improved friction coefficient μ, the wear scar under 600 N load, and more. Using the method specified in the invention, it is possible to make significant improvements to the quality of a lubricant at relatively low cost. | 2013-08-29 |
20130225461 | Lubricating Composition Containing an Antiwear Agent - The invention provides a lubricating composition containing an antiwear agent and an oil of lubricating viscosity. The invention further relates to the use of the lubricating composition in a mechanical device such as an internal combustion engine, or a driveline device. | 2013-08-29 |
20130225462 | TERPENE DERIVED COMPOUNDS - This invention relates to terpene derived compounds and farnesene derived compounds, and to the use of such terpene derived compounds and farnesene derived compounds in lubricants, detergents, dispersants, functional fluids, fuels, polymer compositions, cold flow improvers, and the like. | 2013-08-29 |
20130225463 | QUATERNIZED POLYETHER AMINES AND THEIR USE AS ADDITIVE FOR FUELS AND LUBRICANTS - The present invention relates to novel quaternized polyetheramines and to the preparation thereof. The present invention further relates to the use of these compounds as a fuel and lubricant additive. More particularly, the invention relates to the use of these quaternized nitrogen compounds as a fuel additive for reducing or preventing deposits in the injection systems of direct injection diesel engines, especially in common rail injection systems, for reducing the fuel consumption of direct injection diesel engines, especially of diesel engines with common rail injection systems, and for minimizing power loss in direct injection diesel engines, especially in diesel engines with common rail injection systems. The invention also provides additive packages comprising these polyetheramines; and fuels and lubricants additized therewith. The invention further relates to the use of these quaternized nitrogen compounds as an additive for gasoline fuels, especially for improving the intake system cleanliness of gasoline engines. | 2013-08-29 |
20130225464 | CLEANING LIQUID FOR SEMICONDUCTOR DEVICE SUBSTRATES AND CLEANING METHOD - The invention relates to a cleaning liquid for semiconductor device substrates, which is for use in a step of cleaning a semiconductor device substrate to be conducted after a chemical mechanical polishing step in semiconductor device production, the cleaning liquid including the following components (A) to (D):
| 2013-08-29 |
20130225465 | PROCESSES AND COMPOSITIONS FOR CLEANING MIXING DEVICES TO IMPROVE POLYCARBONATE PRODUCTION - Processes and compositions for cleaning mixing devices are disclosed that improve the production and quality of polycarbonate resins subsequently produced in the mixing device, while reducing the time needed for cleaning and/or change over. A cleaning mixture comprising polycarbonate resin pellets coated with an alkyl aryl sulfonate salt aqueous solution are used to purge the mixing device. | 2013-08-29 |
20130225466 | Subtilase Variants - The present invention relates to novel subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dishwash compositions, including automatic dishwash compositions. | 2013-08-29 |
20130225467 | COMPOSITION AND METHOD TO PREVENT ANIONIC POLYMER PRECIPITATION - The present invention relates to an automatic dishwashing composition including from about 0.1 to 5 weight, percent cross-linked anionic polyacrylate polymer, from about 0.1 to 40 weight percent alkali metal citrate chelating agent and from about 1 to 40 weight percent alkali metal sulfate, with from about 0.1 to 20 weight percent nonionic surfactant and from about 0.05 to 8.0 weight percent bleaching agent as optional components. The present invention also relates to a method for reducing residues on washed and dried dish surfaces, which includes the use of an automatic dishwashing composition containing the above components, | 2013-08-29 |
20130225468 | METHODS FOR PRODUCING LIQUID DETERGENT PRODUCTS - Disclosed herein are methods for producing liquid detergent products using a vessel comprising an inlet, an outlet, an agitation device, and an additive mixing zone disposed between the inlet and the outlet. The method comprises introducing an unstructured liquid detergent precursor into the inlet of the vessel; mixing an additive and the unstructured liquid detergent precursor in an additive mixing zone to form a combined additive detergent; adding a structurant to the combined additive detergent downstream of the additive mixing zone to form a liquid detergent product. The liquid detergent products may be used in a water-soluble pouch, for e.g., a multi-compartment water-soluble pouch. | 2013-08-29 |
20130225469 | HARD SURFACE CLEANERS BASED ON COMPOSITIONS DERIVED FROM NATURAL OIL METATHESIS - Aqueous hard surface cleaner compositions derived from metathesized natural oil feedstocks are disclosed. In one aspect, the compositions comprise at least one anionic surfactant derived from a metathesis-derived C10-C17 monounsaturated acid, 5 octadecene-1,18-dioic acid, or their ester derivatives. In another aspect, aqueous hard surface cleaners comprising at least one nonionic or amphoteric surfactant derived from a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives are disclosed. The aqueous cleaners noted above rival or outperform commercial baselines in a Gardner straight-line washability test. Industrial degreasers comprising a C10 or C12 amide solvent and derived from a metathesis-derived C10-C17 monounsaturated acid are superior to commercial standards. | 2013-08-29 |
20130225470 | FATTY AMIDES AND DERIVATIVES FROM NATURAL OIL METATHESIS - Fatty amide compositions and their derivatives are disclosed. The fatty amides comprise a reaction product of a metathesis-derived C | 2013-08-29 |
20130225471 | COMPOSITION FOR CLEANING AND ARTICLE INCLUDING THE SAME - A composition for cleaning a surface and an article including a substrate and the composition for cleaning the surface are provided herein. The composition comprises a biocide, a first alcohol alkoxylate, an alkyl polyglycoside, a supplemental alcohol alkoxylate, and water. The composition is substantially free of organic solvents and has a cleaning performance of from 30% to 70% as determined in accordance with the Federal Test method Std. No. 536A/GEN, “Soap and Soap-Products (Including Synthetic Detergent)”. | 2013-08-29 |
20130225472 | SOLID COMPOSITIONS CONTAINING GLYCOL ETHER AND WATER - Provided are solid compositions comprising a glycol ether, a gelling agent, and water. Also provided are methods of making such compositions. | 2013-08-29 |
20130225473 | SULFONATES FROM NATURAL OIL METATHESIS - Sulfonate compositions are disclosed. The compositions include alkanesulfonates, alkenesulfonates, sultones, and hydroxy-substituted alkanesulfonates. The sulfonates comprise a reaction product of a metathesis-derived C10-C17 monounsaturated acid, octadecene-1,18-dioic acid, or their ester derivatives with a sulfonating or sulfitating agent. In one aspect, the sulfonate composition is a sulfo-estolide made by reacting a metathesis-derived C10-C17 monounsaturated acid or octadecene-1,18-dioic acid with a sulfonating agent, optionally in the presence of a saturated fatty acid. The sulfonates are valuable for a wide variety of end uses, including cleaners, fabric treatment, hair conditioning, personal care (liquid cleansing products, conditioning bars, oral care products), paint additives, antimicrobial compositions, agricultural uses, and oil field applications. | 2013-08-29 |
20130225474 | FAST DRYING AND FAST DRAINING RINSE AID - The present invention is directed to rinse aid compositions and methods for making and using the rinse aid compositions. The compositions of the invention include a sheeting agent, a defoaming agent, and an association disruption agent. The rinse aid compositions of the present invention result in a faster draining/drying time on most substrates compared to conventional rinse aids. The rinse aid compositions of the present invention are especially suitable for use on plastic substrates. | 2013-08-29 |
20130225475 | Fabric Conditioners Containing Soil Releasing Polymer - A fabric softening composition containing poly(vinyl alcohol)-poly(ethylene glycol) graft copolymers. The copolymer can be effectively deposited on the fabric from the fabric softening composition to provide protection from soil and enhanced soil removal on a broad range of fabric including nylon and cotton. | 2013-08-29 |
20130225476 | NOVEL BIOPOLYMER HAVING EXCELLENT TENSILE STRENGTH, EXTENSIBILITY AND TOUGHNESS - The present invention relates to a biopolymer having excellent tensile strength, extensibility and toughness. The present invention further relates to a nucleic acid molecule encoding the biopolymer of the invention, a vector comprising the nucleic acid molecule of the invention and a non-human host transformed with the vector of the invention. Furthermore, the present invention relates to methods for producing a biopolymer of the invention and to foams, films, gels, coatings, particles, capsules, springs or nonwoven mats as well as fibres comprising or consisting of the biopolymer of the invention. The present invention also relates to a method of producing fibres and the biopolymer of the invention for use in medicine, agriculture, cosmetics as well as surface, paper, leather and/or textile processing. | 2013-08-29 |
20130225477 | Oral Lactoferrin in the Treatment of Severe Sepsis - The present invention relates to lactoferrin for use in the treatment of severe sepsis. In particular, the present invention relates to methods of effectively treating sepsis, in particular, severe sepsis, by administering orally a composition of lactoferrin (LF). More particularly, the present invention relates to methods of treating prophylactically or therapeutically sepsis, in particular, severe sepsis, by administering orally a composition of lactoferrin to patients with an APACHE II score ≦25, in particular <25. | 2013-08-29 |
20130225478 | PEPTIDES BASED ON THE TRANSMEMBRANE DOMAIN OF A TOLL-LIKE RECEPTOR (TLR) FOR TREATMENT OF TLR-MEDIATED DISEASES - Peptides are provided that are capable of inhibiting cell activation mediated by a Toll-like receptor (TLR) selected from TLR 1, 2, 4 or 6, said peptide comprising a sequence consisting of, or found within, the sequence of the transmembrane domain of a TLR selected from TLR 1, 2, 4 or 6 and optionally cytoplasmic and extracellular regions flanking the transmembrane domain. These peptides as well as pharmaceutical composition comprising them are useful for the treatment of TLR-mediated disease. | 2013-08-29 |
20130225479 | Methods and Compositions for Treating Inflammation - The present invention provides methods and compositions for treating inflammation and inflammatory disorders in a subject, by administering an effective amount of KSHV-Orf63 and/or active peptides and/or fragments thereof. | 2013-08-29 |
20130225480 | Method of Treating Chronic Obstructive Pulmonary Disease - The present invention relates to a method of promoting bronchodilation by administration of streptolysin O to a subject in need thereof. | 2013-08-29 |
20130225481 | ANTIMICROBIAL PEPTIDES - The present invention relates to antimicrobial peptides, to their use as antimicrobial agents and to their use in the treatment of (infectious) diseases, in particular infectious diseases caused by Gram-positive bacteria, Gram-negative bacteria, yeast or fungi. The present invention further relates to pharmaceutical compositions and kits comprising the antimicrobial peptides and to a method of lysing bacterial, yeast or fungal cells. The antimicrobial peptides consist of one of the following general formula: Wherein X is a hydrophobic amino acid, Y is a cationic amino acid, Z is an amino acid having a free thiol or thioether group, n is 2-4 and m is 0 or 1. | 2013-08-29 |
20130225482 | CASPOFUNGIN ANALOG, AND PREPARATION METHOD AND USES THEREOF - Disclosed are a caspofungin analog, and a preparation method and applications thereof. The caspofungin analog has a structure as represented in Formula 3. | 2013-08-29 |
20130225483 | New Treatments of Hepatitis C Virus Infection - The invention concerns the use of cyclophilin inhibitors in the treatment of Hepatitis C virus genotype 2 or 3 infection. | 2013-08-29 |
20130225484 | STABILIZED RECEPTOR POLYPEPTIDES AND USES THEREOF - The present invention provides stabilized activin IIB receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the stabilized polypeptides and proteins. Compositions and methods for treating muscle-wasting diseases and metabolic disorders are also provided. | 2013-08-29 |
20130225485 | Compositions and Methods for the Control, Prevention and Treatment of Obesity and Eating Disorders - Compositions and methods for preventing, treating or controlling conditions or disorders associated with obesity, diet and nutrition are provided. The methods provided generally involve the administration of an Amylin or an Amylin agonist to a subject in order to prevent, treat or control conditions or disorders associated with obesity, diet and nutrition. | 2013-08-29 |
20130225486 | CYSTEINE AND FOOD INTAKE - The present invention relates to the field of nutrition; in particular to the prevention and/or treatment of malnutrition. One embodiment of the present invention relates to a nutritional composition enriched in cysteine for use in the treatment and/or prevention of malnutrition and disorders related thereto. Such a composition may in particular, but not exclusively, be useful for the elderly population. | 2013-08-29 |
20130225487 | DIOXA-BICYCLO[3.2.1]OCTANE-2,3,4-TRIOL DERIVATIVES - Compounds of Formula (A) and (B) are described herein and the uses thereof for the treatment of diseases, conditions and/or disorders mediated by sodium-glucose transporter inhibitors (in particular, SGLT2 inhibitors). | 2013-08-29 |