35th week of 2014 patent applcation highlights part 58 |
Patent application number | Title | Published |
20140243403 | TREATING COLORECTAL, PANCREATIC, AND LUNG CANCER - The invention relates to methods of determining an appropriate chemotherapy for a subject based on expression levels of a TAK1 biomarker, such as one or more TAK1 biomarkers listed in Table 1, or any subset or combination thereof, e.g., a set of biomarkers consisting of or comprising GGH, BMP7, BAMBI, MBOAT2, HSPA12A, FYN, NAV2, RGL1, SYK and RUNX1 genes, optionally with one or both of INHBB and/or BMPR1A. In some embodiments, the biomarkers include one, two, three, or all of BMP7, BAMBI, BMPR1A, and INHBB. Kits useful for the methods are also provided. | 2014-08-28 |
20140243404 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY - This disclosure is related to halonium compounds useful for cyclization of polyenes, alkenoic acids, and alkenyl alkyl ethers, and halogenation of aromatic compounds. The synthesis of such halonium compounds, compounds made using such halonium compounds, and synthesis of natural compounds, including decalins, using the halonium compounds is also disclosed. A representative halonium compound of the disclosure is: | 2014-08-28 |
20140243405 | A PHARMACEUTICAL COMPOSITION COMPRISING THE PHYTOCANNABINOIDS CANNABIDIVARIN (CBDV) AND CANNABIDIOL (CBD) - This invention relates to a pharmaceutical composition comprising or consisting essentially of the phytocannabinoids cannabidivarin (CBDV) and cannabidiol (CBD). The composition is particularly safe and efficacious for use in the treatment of neurological conditions, characterized by hyper-excitability of the central nervous system, convulsions or seizures such as occur in epilepsy. Preferably the CBDV and the CBD are present with at least one non-cannabinoid component of | 2014-08-28 |
20140243406 | Methods for Treating or Preventing Fatigue - The present invention relates to the use of compounds of the invention for treatment and/or prevention of fatigue, including fatigue associated with diseases or treatments. | 2014-08-28 |
20140243407 | ACETAMINOPHEN CONJUGATES, COMPOSITIONS AND METHODS OF USE THEREOF - Acetaminophen conjugates are provided, which have an acetaminophen moiety covalently linked to a second moiety. The conjugates provided may have one or more advantageous properties, including increased water solubility as compared to acetaminophen, reduced toxicity profile as compared to acetaminophen and an altered pharmacokinetic profile. Formulations comprising the conjugates are also provided, as are methods of using the conjugates and kits comprising the conjugates. | 2014-08-28 |
20140243408 | USE OF AMINOACETONITRILE DERIVATIVES AGAINST ENDOPARASITES - The present invention relates to a method of treating a parasitic infection in an animal, particularly a filarial endoparasitic infection, comprising administering an effective amount of a Formula (I) compound or a Formula (II) compound | 2014-08-28 |
20140243409 | PHARMACEUTICAL COMPOSITIONS HAVING DESIRABLE BIOAVAILABILITY - The present invention is directed to the provision of pharmaceutical compositions. The compositions include a therapeutic agent and a relatively low amount of surfactant for providing higher bioavailability of the therapeutic agent. The compositions are particularly desirable as ophthalmic compositions in which the therapeutic agent is a prostaglandin such as travoprost and the surfactant is a vegetable oil such as castor oil. | 2014-08-28 |
20140243410 | COMPOSITIONS FOR USE IN SURGERY - A method is provided for treating a subject in need of medication as an adjunct to elective surgery, comprising administration of a ketogenic material sufficient to produce a physiologically acceptable ketosis in the patient. Preferably the surgery is selected from the groups consisting of removal or section of tumours, removal of redundant organs such as lymph nodes and appendix, open heart surgery, cosmetic surgery, joint and bone surgery. | 2014-08-28 |
20140243411 | TOPICAL DTPA PRODRUG FORMULATIONS AND METHODS OF USING THE SAME - The present invention relates to topical trisodium diethylenetriamine pentaacetic acid (DTPA) prodrug formulations and methods of using the same. | 2014-08-28 |
20140243412 | PROCESS FOR PREPARATION OF PREGABALIN - Aspects of the present invention relate to improved process for preparation of (R)(−)-3-(carbamoylmethyl)-5-methylhexanoic acid (R-CMHA) of the formula (II) or its pharmaceutically acceptable salts in the presence of a lewis acid, process for preparation of pregabalin using R-CMHA of the formula (II) or its pharmaceutically acceptable salts prepared according to the present invention and process for preparation of pregabalin with low amount of undesired impurity. | 2014-08-28 |
20140243413 | AQUEOUS LIQUID PREPARATION CONTAINING 2-AMINO-3-(4-BROMOBENZOYL)PHENYLACETIC ACID - An aqueous liquid preparation of the present invention containing 2-amino-3-(4-bromobenzoyl)phenylacetic acid or its pharmacologically acceptable salt or a hydrate thereof, an alkyl aryl polyether alcohol type polymer such as tyloxapol, or a polyethylene glycol fatty acid ester such as polyethylene glycol monostearate is stable. An embodiment of said liquid preparation does not include any preservative. Said aqueous liquid preparation in the form of an eye drop is useful for the treatment of blepharitis, conjunctivitis, scleritis, and postoperative inflammation. Also, the aqueous liquid preparation of the present invention in the form of a nasal drop is useful for the treatment of allergic rhinitis and inflammatory rhinitis (e.g. chronic rhinitis, hypertrophic rhinitis, nasal polyp, etc.). | 2014-08-28 |
20140243414 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS - The invention provides pharmaceutical compositions comprising a cholesteryl ester transfer protein (CETP) inhibitor and a water-insoluble concentration-enhancing additive, which exhibit improved bioavailability. The invention also provides methods of treating cardiovascular disorders comprising the administration of the pharmaceutical compositions comprising a CETP inhibitor. | 2014-08-28 |
20140243415 | COMPOUNDS INHIBITING GALECTIN-1 EXPRESSION, CANCER CELL PROLIFERATION, INVASION, AND TUMORIGENESIS - Disclosed herein are compositions comprising a galectin-1-targeting compound in a therapeutically effective composition for treating cancer. In an aspect, a galectin-1-targeting compound is OTX-008. Also disclosed herein are methods of making and using such compositions. | 2014-08-28 |
20140243416 | Topical Antiandrogen Therapy for the Treatment of Becker's Nevus - This invention relates to the treatment of Beckers nevus with antiandrogenic topical agents, including 5-alpha reductase inhibitors, non-steroidal antiandrongens and steroidal antiandrogens. | 2014-08-28 |
20140243417 | Composition with Sustained Antimicrobial Activity - Disclosed herein are compositions comprising benzyl alcohol, one or more cationic antimicrobial agent, and one or more emollient, the combination of which results in persistent antimicrobial activity after application to the skin. The compositions optionally further comprise an organic acid and/or a zinc salt, such as zinc gluconate, as an anti-irritant. | 2014-08-28 |
20140243418 | RASAGILINE FOR PARKINSON'S DISEASE MODIFICATION - A method for modifying Parkinson's disease by periodically administering a pharmaceutical composition comprising a therapeutically effective amount of rasagiline or a pharmaceutically acceptable salt of rasagiline to the patient, thereby modifying the disease. The method includes reducing the rate of progression; delaying the need for symptomatic anti-Parkinsonian therapy; reducing the risk of a Parkinson's disease patient requiring symptomatic anti-Parkinsonian therapy; and reducing the functional decline. | 2014-08-28 |
20140243419 | MUCOSALLY-APPLIED AGENT FOR PREVENTION, AMELIORATION OR TREATMENT OF RETINAL DISEASE - Application of a pharmaceutical preparation comprising geranylgeranylacetone to the mucosa of, for example, the eye, nose, oral cavity or pharynx can efficiently prevent, ameliorate or treat retinal diseases such as glaucoma, retinitis pigmentosa, age-related macular degeneration, and diabetic retinopathy. | 2014-08-28 |
20140243420 | ANTICONVULSANT ACTIVITY OF TURMERIC OIL AND BISABOLENE SESQUITERPENOIDS - The present invention relates to the anti-convulsant activity of turmeric oil and its volatile bisabolene sesquiterpenoids ar-turmerone, α-turmerone, β-turmerone (curlone) and α-atlantone, as an anticonvulsant agent for the treatment of epilepsy and/or as therapeutic agents for the treatment of disorders of the central nervous system, including tremor, pain, mood disorders (including depression, bipolar disorder, attention deficit-hyperactivity disorder, and schizophrenia), and neurodegenerative diseases. | 2014-08-28 |
20140243421 | BIOLOGICALLY ACTIVE COMPOSITIONS CONTAINING PHENOLIC RESIDUE - A composition for controlling pests. The composition includes an aqueous mixture of at least one phenolic aldehyde and a bisulfite salt with a suitable surfactant and a sufficient amount of the bisulfite salt to solubilize the aldehyde(s). A stable apparent solution is formed. | 2014-08-28 |
20140243422 | METHODS OF TREATING BEHAVIORAL AND PSYCHIATRIC DISORDERS - The invention relates to the treatment of disorders associated with elevated myo-inositol levels in brain, in particular behavioural and neuropsychiatry disorders such as dementia, mild Alzheimer's disease, mild cognitive impairment or bipolar disorder by administering an effective amount of scyllo-inositol to a subject. | 2014-08-28 |
20140243423 | Stable, Non-Irritating Topical Formulations of Hydroquinone - Described herein are methods and compositions for increasing the efficacy and decreasing the irritancy of topical formulations of hydroquinone. | 2014-08-28 |
20140243424 | CATECHOL DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES - Methods of treating or suppressing oxidative stress disorders affecting normal electron flow in the cells, including mitochondrial diseases, impaired energy processing disorders, neurodegenerative diseases, diseases of aging and diseases caused by reactive oxygen species are disclosed, as well as compounds useful in the methods of the invention, such as such as catechol or ortho-quinone derivatives of Formula (I). | 2014-08-28 |
20140243425 | CONTROLLED RELEASE COMPOSITIONS FOR MODULATING FREE-RADICAL INDUCED DAMAGE AND METHODS OF USE THEREOF - Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with free-radical modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s). | 2014-08-28 |
20140243426 | COMPOSITION FOR CRYOPRESERVATION OF CELLS AND TISSUES - A composition for cryopreservation of cells and tissues of human and other animals in a safe manner without using toxic substances such as DMSO, as well as for freeze preserving or freeze-drying of foods and pharmaceuticals. In embodiments, ε-poly-L-lysine is reacted with succinic anhydride so that 60% or more of amino groups are blocked; and, thus obtained polymer compound is added to Dulbecco-modified eagle MEM culture medium (DMEM) on market sale to form a cryopreservation liquid. In embodiments for foods or pharmaceuticals, the ε-poly-L-lysine derivative was added by 0.5-10 wt % to curb freeze concentration. | 2014-08-28 |
20140243427 | Process for Preparing a Synthetic Foam Having a Controlled Particle Distribution - The invention relates to processes for preparing a synthetic foam having present therein particles with a controlled particle distribution and the use of said foam, as well as to foams as such. Accordingly the invention is directed to a process for preparing a synthetic foam having present therein particles, wherein the distribution of said particles is controlled by the following steps of dissolving at least one synthetic polymer in one or more solvents to form a solution; contacting particles with said solution to form a polymer/particles mixture; and freeze-drying the polymer/particles mixture by: freezing the polymer/particles mixture; and subsequently subliming the one or more solvents to form a synthetic foam comprising said particles. | 2014-08-28 |
20140243428 | SELF HEALING HYDROGELS - The disclosure provides for self-healing hydrogels, complex structures made therefrom, and use thereof, including use of the hydrogels as self-healing coatings, self-healing sealants, tissue adhesives, and drug carriers. | 2014-08-28 |
20140243429 | Enzyme-Degradable Polymer and Application Thereof - The present invention belongs to the biomedicine field and specifically concerns an enzyme-degradable polymer and the application thereof. To solve the problem of low sensitivity of the existing assay reagents, the present invention provides an enzyme-degradable polymer and the related application of the polymer. The present invention also provides hydrogels, nano-particles, fluorescent dye-labeled enzyme substrates and kits (packages) for detection or activity-analysis of biological enzymes based on the enzyme-degradable polymer. The formula of the enzyme-degradable polymer is P | 2014-08-28 |
20140243430 | ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS - The present invention is embodied by a composition capable inducing weight loss in a patient in need thereof. | 2014-08-28 |
20140243431 | FLOURESCENT IN-SITU DETECTION OF LIPID PARTICLE APOLIPOPROTEINS WITHIN PRIMARY ELECTROPHORETIC MATRIX - The present invention relates to, among other things, a gel electrophoresis system for detecting the level of specific Apolipoproteins and/or lipoprotein particles present in intact lipid particles in a biological sample. The system includes a gel substrate to receive a biological sample, at least two lipoprotein-binding complexes. Each complex includes an antibody that binds a lipoprotein particle or a portion thereof, which is bound to a signal producing molecule capable of producing or causing production of a detectable signal. The system also includes a device for detecting the detectable signal. The present invention also relates to methods of assessing the level of specific Apolipoproteins and/or lipoprotein particles present in a biological sample, determining whether a subject is at increased risk for cardiovascular disease, and monitoring the risk for developing cardiovascular disease. | 2014-08-28 |
20140243432 | PEPTIDE BIOMARKERS OF CARDIOVASCULAR DISEASE - The presently-disclosed subject matter provides methods for diagnosing a cardiovascular disease in a subject by determining an amount of one or more peptide biomarkers disclosed herein in a biological sample from the subject. The presently-disclosed subject matter further provides methods for determining treatment efficacy and/or progression of a cardiovascular disease in a subject by measuring amounts of one or more of the biomarkers in a biological sample from the subject. The presently-disclosed subject matter also provides antibodies and kits for measuring the biomarkers. | 2014-08-28 |
20140243433 | MARKER GENES FOR PROSTATE CANCER CLASSIFICATION - The present invention relates to a method for classifying a prostate cancer in a subject, the method comprising the steps of a) determining a gene expression level or gene expression pattern of the genes F3 and IGFBP3in a sample from the subject and b) classifying the tumor by comparing the gene expression level determined in a) with a reference gene expression of the same genes in reference patients known to have a high risk or low risk tumor respectively. In addition the invention relates to a method for determining prognosis of a subject diagnosed with prostate cancer, a method for making a treatment decision for a subject diagnosed with prostate cancer and a solid support or a kit for classifying a tumor in a subject diagnosed with prostate cancer. | 2014-08-28 |
20140243434 | WATER CLUSTERS CONFINED IN NANO-ENVIRONMENTS - The disclosure describes a method including providing a nano-environment; and confining heavy or light water in the nano-environment such that at least one water cluster forms. | 2014-08-28 |
20140243435 | Production of Methanol and Ethanol from CO or CO2 - This invention relates to a process for making methanol and ethanol from carbon dioxide and hydrogen. The process includes contacting a mixture of carbon dioxide and hydrogen with a catalyst system containing a ruthenium compound—and optionally, a chloride or bromide-containing compound—dispersed in a low-melting tetraorganophosphonium chloride or bromide salt under conditions effective to produce methanol and ethanol. The invention also relates to a process for making methanol and ethanol from carbon monoxide and water using the same catalyst system. | 2014-08-28 |
20140243436 | FISCHER-TROPSCH CATALYST COMPRISING COBALT, MAGNESIUM AND PRECIOUS METAL - A method is described for preparing a catalyst precursor suitable for use in the Fischer-Tropsch synthesis of hydrocarbons including 10 to 40% by weight of cobalt oxide crystallites and 0.05 to 0.5% by weight of a precious metal promoter, dispersed over the surface of a porous transition alumina wherein the surface of the transition alumina has been modified by inclusion of 0.25 to 3.5% wt magnesium, including the steps of:
| 2014-08-28 |
20140243437 | Paint Composition For Forming Three-Dimensional Film - A paint composition for forming a three-dimensional film including 1 to 10 wt % of a polymer hollow microsphere and 5 to 40 wt % of a polymer resin based on a total weight of the composition, wherein the polymer hollow microsphere has a density of 10 to 100 kg/m | 2014-08-28 |
20140243438 | THERMALLY FOAMABLE MICROSPHERE, METHOD OF PRODUCING THE SAME, AND USE THEREOF - This invention aims to provide a thermally foamable microsphere which is excellent in heat resistance, has a high expansion ratio, and shows stable foaming behavior; a method of producing the thermally foamable microsphere; and suitable use thereof. | 2014-08-28 |
20140243439 | MODIFIED POROUS MATERIALS AND METHODS OF CREATING INTERCONNECTED POROSITY IN MATERIALS - Techniques, mixtures and improved porous materials (interconnected porous constructs) that are capable of maintaining a sufficient porosity while conferring improved mechanical and physical strength to the final construct. A sacrificial construct (for example, a sacrificial material such as polymethyl methacrylate (PMMA)) is used to obtain an inverse porosity of the construct it was molded into. The process provides a less porous end material that may be used as an arthroplasty device or surgical implant (for example, an interference screw of suture anchor) among many other applications. The process employs a sacrificial material to reduce the porosity of the final construct to about 35%. | 2014-08-28 |
20140243440 | METHOD - A method for producing a porous polymer structure involves (i) forming a polymer; (ii) subsequently contacting the polymer with a nonsolvent and inducing the formation of an emulsion in which the nonsolvent is present as the dispersed phase and the polymer as the continuous phase; and (iii) removing at least some of the nonsolvent so as to leave pores within the polymer, wherein the polymer is formed by exciting one or more molecules in an exciting medium, in particular by pulsed plasma deposition. Emulsion formation in step (ii) may be induced by or in the presence of an emulsion stabilising agent. Also provided is a porous polymer structure produced using the method, and a polymer which is impregnated with an emulsion stabilising agent, for use in the emulsion formation step of the method. | 2014-08-28 |
20140243441 | LADDER POLYMERS WITH INTRINSIC MICROPOROSITY AND PROCESS FOR PRODUCTION THEREOF - A polymer of formula (I): | 2014-08-28 |
20140243442 | MOULDING OF PLASTIC PARTICULATE MATTER - A method of manufacturing a moulded article from expanded resin particles, the method comprising: placing the particles and a dielectric heat transfer fluid in a mould located between a pair of electrodes; generating a radio-frequency electromagnetic field between the electrodes; applying the electromagnetic field to the mould to dielectrically heat the heat transfer fluid and hence the particles; and heating the particles to a temperature sufficient to cause their surfaces to soften, so that the particles fuse, thereby to form the moulded article as shaped by the mould; preferably, wherein the radio-frequency electromagnetic field has a wavelength greater than an average dimension (or dimensions) of the moulded article. | 2014-08-28 |
20140243443 | HYDROPHILICITY ALTERATION SYSTEM AND METHOD - A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age. | 2014-08-28 |
20140243444 | (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING THE SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION - The purpose of the present invention is to provide a polymer having a low halogen atom content remaining in the polymer, a simple production method thereof, an active energy ray-curable composition that can be rapidly cured by an irradiation of a small amount of light, and a cured product thereof. These purpose can be achieved by an active energy ray-curable composition, including a polyisobutylene polymer (A) represented by the following general formula (1) (wherein R | 2014-08-28 |
20140243445 | FLUORESCENT PASTES AND FILMS - A fluorescent paste that can form a fluorescent film and can be manufactured without a binder resin and has a high recording density and peel resistance Fluorescent fine particles each coated with a film formed of a film compound having a reactive group and a curing agent having a plurality of crosslinking reaction groups each reacting with the reactive group to form bonds are blended with a solvent to manufacture fluorescent paste. The fluorescent paste is applied to a substrate coated with a film formed of a second film compound having a second reactive group and is cured by crosslinking reactions between the reactive group and the second reactive group, and the crosslinking reaction groups to form a fluorescent film. | 2014-08-28 |
20140243446 | ENVIRONMENTALLY FRIENDLY COALESCING AGENTS - A composition may include a binder; a coalescing agent with the general formula of | 2014-08-28 |
20140243447 | CONJUGATED DIENE POLYMER END-MODIFIED WITH ALKOXYSILANE DERIVATIVE - The present invention relates to a conjugated diene polymer end-modified with an alkoxysilane derivative. More particularly, the present invention relates to an end-modified conjugated diene polymer, wherein an alkoxysilane derivative having an ether group and a dialkylamino group is bonded as end modifier to an end of a conjugated diene polymer, which is useful as a rubber material for a tire tread owing to improved compatibility with an inorganic reinforcing agent and improves dynamic mechanical properties such as wet traction, rolling resistance, Mooney viscosity, processability, etc. | 2014-08-28 |
20140243448 | TIRE WITH IMPROVED GRIP ON WET GROUND - A tire having an improved wet grip, in particular for a passenger vehicle, a van, or two-wheel vehicle, includes a tread of which includes a rubber composition. The rubber composition includes at least (phr meaning parts by weight per hundred parts of elastomer):
| 2014-08-28 |
20140243449 | METHOD OF PREPARING ENCAPSULATED PIGMENT DISPERSIONS WITH TWO ENCAPSULATION STEPS - A process for encapsulating pigment dispersions is provided where a pigment is dispersed with a polymeric dispersant in an aqueous solvent system. The encapsulation process has at least two additions of encapsulating monomers followed by polymerization. To a pigment dispersed with a polymeric dispersant is added an encapsulating monomer(s) and a polymerization initiator is added which forms a stage 1 encapsulated pigment. Then a second encapsulating monomer(s) is added and these monomers are polymerized by a second addition of polymerization initiator, forming a second stage encapsulated pigment. The second encapsulating monomer(s) may be added continuously to the stage 1 encapsulated pigment. Such encapsulated pigment dispersions may be used in inkjet inks and are stable to heat, aging test conditions, and solvent challenges. Prints from these inks have better durability. | 2014-08-28 |
20140243450 | PROCESS FOR PRODUCING POLYMER-SHELL NANOPARTICLES - The invention provides a continuous process for producing polymer-shell nanoparticles, especially in the form of aqueous dispersions, using a high-pressure homogenizer. | 2014-08-28 |
20140243451 | RUBBERY POLYMER WITH LOW COMPRESSION SET - A rubbery polymer comprising:
| 2014-08-28 |
20140243452 | DISPERSIONS AND RELATED COATINGS AND CURED ARTICLES - A pre-dispersion composition comprising (i) a silsesquioxane; (ii) a dispersing agent; and (iii) a curable resin. | 2014-08-28 |
20140243453 | CONDUCTIVE RESIN COMPOSITION AND CURED PRODUCT THEREOF - A conductive resin composition which includes an epoxy resin (A), a compound (B) having a (meth)acryloyl group and a glycidyl group, a phenolic resin curing agent (C), a radical polymerization initiator (D) and a conductive particle (E). The conductive resin composition which may be B-staged (semi-cured) at a relatively low temperature to exhibit sufficient tack-free properties and excellent pressure-sensitive tackiness. This permits temporary bonding of parts without involving solvent evaporation or light illumination, thereby reducing or avoiding an increase in facility costs. The conductive resin composition may thereafter be cured (C-staged) to provide a cured product having a desirable bond strength, while maintaining a low specific resistivity. | 2014-08-28 |
20140243454 | NON-HALOGEN FLAME RETARDANT STYRENE RESIN COMPOSITION - Disclosed is a non-halogen flame retardant styrene resin composition which comprises (a) a styrene resin and (b) a phosphorous-modified epoxy resin and thus exhibits superior flame retardancy to external candle flame ignition. | 2014-08-28 |
20140243455 | P-PIPERAZINE COMPOUNDS AS FLAME RETARDANTS - The present invention relates to the use of aromatic P-piperazine-compounds in flame retardant polymer compositions. These compositions are especially useful for the manufacture of flame retardant compositions based on thermoplastic polymers, especially polyolefin homo- and copolymers, polycondensates, such as polyamines or polyesters and duroplastic polymers, such as polyepoxides. | 2014-08-28 |
20140243456 | Anhydride Accelerators for Epoxy Resin Systems - Carboxylic acid salts of tertiary amines for use as an accelerator for an anhydride based epoxy curing agents are disclosed. The disclosed carboxylic acid salts of certain tertiary amines are latent anhydride accelerators and enable epoxy resin curing when heated to an elevated temperature (e.g., an onset temperature of greater than about 50° C.). | 2014-08-28 |
20140243457 | DRY BUILDING MATERIAL FORMULATIONS CONTAINING POLYMER POWDERS - Hydraulically setting compositions containing mineral binders exhibit improved adhesion when polymer powders produced by drying a silica sol and a redispersible polymer powder emulsion are added. | 2014-08-28 |
20140243458 | POWDERY HYDROPHILIC POLYMER, METHOD FOR PRODUCING THE SAME, AND FLOCCULATING AGENT USING SAME - Provided is a powdery hydrophilic polymer by aggregating a hydrophilic polymer comprising a water-in-oil emulsion in a liquid form by emulsion breaking and granulating the aggregate, followed by drying. As an emulsion breaker, ionic surfactants, nonionic surfactants having an HLB value of 11 to 20, or oil-soluble polymer compounds having a hydrophilic group and a hydrophobic group can be used. The powdery hydrophilic polymer obtained by this method exhibits excellent effects as a flocculating agent. | 2014-08-28 |
20140243459 | Multifilament, Monofilament, Non-Woven or Tape - A multifilament, a monofilament, a non-woven or a tape, each having 1 to 2000 Denier per filament and a draw ratio of 1:2 to 1:11 and each made of a composition containing the components
| 2014-08-28 |
20140243460 | REINFORCED POLY(PHENYLENE ETHER)-POLYSILOXANE BLOCK COPOLYMER COMPOSITION, AND ARTICLE COMPRISING SAME - A reinforced poly(phenylene ether)-polysiloxane block copolymer composition includes specific amounts of a poly(phenylene ether)-polysiloxane block copolymer reaction product, a flame retardant, and a reinforcing filler. The composition exhibits a desirable balance of flame retardancy, heat resistance, and stiffness relative to a corresponding poly(phenylene ether) composition, and it is useful to fabricate articles including fuser holders for electrophotographic copiers. | 2014-08-28 |
20140243461 | REINFORCED POLY(PHENYLENE ETHER)-POLYSILOXANE BLOCK COPOLYMER COMPOSITION, AND ARTICLE COMPRISING SAME - A reinforced poly(phenylene ether)-polysiloxane block copolymer composition includes specific amounts of a poly(phenylene ether)-polysiloxane block copolymer reaction product, a flame retardant, and a reinforcing filler. The composition exhibits a desirable balance of flame retardancy, heat resistance, and stiffness relative to a corresponding poly(phenylene ether) composition, and it is useful to fabricate articles including fuser holders for electrophotographic copiers. | 2014-08-28 |
20140243462 | ALKYL-MODIFIED VINYL ALCOHOL POLYMER SOLUTION - An alkyl-modified PVA solution is provided which has low viscosity at high temperatures leading to superior handleability, accompanied by rapidly increased viscosity upon lowering of the temperature, even in the case in which the concentration of the alkyl-modified PVA in a solution is increased. An alkyl-modified vinyl alcohol polymer solution containing an alkyl-modified vinyl alcohol polymer, a surfactant and water. The alkyl-modified vinyl alcohol polymer has a monomer unit that includes an alkyl group having 5 to 29 carbon atoms. The percentage content of the monomer unit is no less than 0.05 mol % and no greater than 5 mol %. The degree of saponification of the alkyl-modified vinyl alcohol polymer is no less than 20 mol % and no greater than 99.99 mol %. The surfactant is a compound represented by the following formula (I) having hydrophilic groups X | 2014-08-28 |
20140243463 | Polyalkylene Carbonate Diol Paint Composition - Disclosed is a polyalkylene carbonate paint composition, which is a pre-coated metal (PCM) paint composition capable of being applied in various fields for architectural uses, domestic uses, coating a can, or the like, in which high hardness is required. The composition may provide a PCM paint capable of having a low smoke density and significantly decreasing discharge of toxic gas and smoke caused by combustion at the time of fire as compared to the existing laminate steel sheet and high gloss film. In addition, disclosed is a high hardness paint composition capable of being usefully used in a PCM print steel sheet applied to electric home appliances due to an excellent adhesion property to a metal material and excellent durability. | 2014-08-28 |
20140243464 | POLYMERS USEFUL AS DEMULSIFIERS AND CLARIFIERS - A polymer useful as a flocculent, demulsifier or water clarifier may be selected from those having the general formula: | 2014-08-28 |
20140243465 | RESIN COMPOSITION, SEAMLESS BELT, AND IMAGE FORMING APPARATUS - Provided is a resin composition including at least: polyolefin in an amount of from 50% by mass to 90% by mass; an electro-conductive agent; and a compound represented by General Formula (1) below, | 2014-08-28 |
20140243466 | WEAR AND FRICTION PROPERTIES OF ENGINEERING THERMOPLASTICS WITH ULTRA-HIGH MOLECULAR WEIGHT POLYETHYLENE - Disclosed herein are compositions comprising a polymer comprising polyetherimide, polyetheretherketone, polyamide, polyoxyalkylene, or polyalkylene terephthalate, or a mixture thereof, and ultra-high molecular weight polyethylene, wherein the ultra-high molecular weight polyethylene comprises a surface modifier. Also disclosed are articles comprising one or more of the described compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 2014-08-28 |
20140243467 | POLYCARBONATE COMPRISING GLASS FIBRES - The present invention relates to a thermoplastic moulding composition composed of polycarbonate and inorganic fillers which comprises from 0.01 to 0.5 part by weight of at least one anhydride-modified alpha-olefin terpolymer and which has a high degree of rigidity and nevertheless exhibits good strength, as well as stress-strain characteristics corresponding to those of an unreinforced polycarbonate. Surprisingly, the moulding composition additionally exhibits an improvement in flame retardancy. The invention relates in particular to flame-retardant, thermoplastic moulding compositions filled with glass fibres, and to the production and use thereof. The property profile is, surprisingly, independent of the degree of interaction of the filler with the polycarbonate matrix. | 2014-08-28 |
20140243468 | Cross-Linkable Monomers and Polymers and the Use Thereof - The invention relates to novel cross-linkable monomers that may be polymerized with ethylenically unsaturated comonomers to form cross-linkable copolymers. Said copolymers may particularly be used in the form of aqueous dispersions as formaldehyde-free adhesives or as coatings with good water resistance. The cross-linkable monomer is a compound in acid or salt form comprising an anion of the formula (I) and one or more cations for producing electrical neutrality, where R | 2014-08-28 |
20140243469 | AQUEOUS COATING COMPOSITIONS - The invention relates to an aqueous coating composition comprising a dispersion of an acrylic copolymer A, a cross-linker B which is a multifunctional isocyanate B1, or an aminoplast crosslinker B2 or a combination of both B1 and B2, and water, wherein the acrylic copolymer A has moieties derived from alkyl(meth)acrylates A1, from hydroxyalkyl(meth)acrylates A2, from olefinically unsaturated carboxylic acids A3, and optionally, further olefinically unsaturated monomers A4 selected from the group consisting of vinyl aromatics A41, vinyl esters A42, vinyl halogenides A43, olefinically unsaturated amides A44, olefins A45, vinyl ester A46, and from an olefinically unsaturated surface-active compound A5 which has at least one olefinic unsaturation, and at least one hydrophilic group per molecule, a method for its preparation, and the use thereof in coating metal substrates, stone, concrete, paper and cardboard. | 2014-08-28 |
20140243470 | Process of Incorporating Additives into Vinylidene Chloride Polymers Without the use of a Blender - Solid additive particles are added to solid vinylidene chloride (VDC) polymer particles by a process comprising the steps of: A. Polymerizing VDC monomer, optionally with one or more mono-ethylenically unsaturated comonomers, in a polymerization zone under polymerization conditions to form solid VDC polymer particles; B. Stopping the polymerization of the VDC monomers after formation of the solid VDC polymer particles; and C. Contacting the solid VDC polymer particles with the solid additive particles (i) before the solid VDC polymer particles are de-watered, and (ii) at a temperature sufficient to melt or soften the solid additives particles but insufficient to melt or soften the solid VDC polymer particles such that the melted or softened solid additive particles adhere to the solid VDC polymer particles upon contact. | 2014-08-28 |
20140243471 | THERMOPLASTIC ELASTOMER COMPOUNDS EXHIBITING HIGH LATENT HEAT OF FUSION IN SOLID STATE - A thermoplastic elastomer compound is disclosed having a high latent heat of fusion, indicative of a large thermal capacity. Use of thermal capacity agents, particularly linear paraffin waxes used in replacement of conventional plasticizer oils, contributes the thermal capacity advantages. Selection of the particular thermal capacity agent can provide an ability to engineer the amount of thermal capacity and the transition temperature in which that thermal capacity can be utilized as absorption or release of heat. The compound experiences a solid-solid phase transition whenever the thermal capacity agent melts into liquid form in the compound. | 2014-08-28 |
20140243472 | SURFACE PROTECTIVE FILM - Provided is a surface protective film including, as an outermost layer, a pressure-sensitive adhesive layer containing a urethane-based pressure-sensitive adhesive as a main component, the surface protective film allowing the contamination of an adherend to be extremely suppressed, and being preferably excellent in wettability and reworkability. The surface protective film of the present invention includes, as an outermost layer, a pressure-sensitive adhesive layer containing, as a main component, a urethane-based pressure-sensitive adhesive containing a polyurethane-based resin; and when a pressure-sensitive adhesive layer side of the surface protective film is attached to a glass plate at 50° C. for 10 days and then the surface protective film is peeled from the glass plate, a residual adhesive strength on the peeled surface side of the glass plate is 3.0 N/19 mm or more. | 2014-08-28 |
20140243473 | METHOD AND DEVICE FOR DIRECT, CONTINUOUS MODIFICATION OF POLYMER MELTS - The invention relates to a method for direct, continuous modification of polymer melts with additives in the side stream and is distinguished by a very high degree of flexibility in product change-overs. | 2014-08-28 |
20140243474 | Graft Polyol And Method Of Forming The Same - A graft polyol includes a natural oil including at least 50% by weight of a natural oil polyol. Particles are dispersed in the natural oil and comprise the reaction product of a macromer polyol, a polymerizable monomer, a chain transfer agent, and a free radical initiator. The macromer polyol and the polymerizable monomer react in the presence of the natural oil. The graft polyol is formed by providing the natural oil and providing the macromer polyol, the chain transfer agent, the free radical initiator, and the polymerizable monomer. The natural oil, the polymerizable monomer, the macromer polyol, the chain transfer agent, and the free radical initiator are combined, and the polymerizable monomer, the macromer polyol, the chain transfer agent, and the free radical initiator react to form particles dispersed in the natural oil. | 2014-08-28 |
20140243475 | POLYETHYLENE PROCESSES AND COMPOSITIONS THEREOF - Embodiments of the present disclosure relate to a method of preparing polyethylene compositions comprising polymerizing ethylene in a first gas-phase reactor and polymerizing ethylene in a second gas-phase reactor in the presence of hydrogen; wherein at least one of the first or second gas-phase reactors comprises a first and second polymerization zone; wherein a hydrogen pressure of the first and second polymerization zones are different such that at least a portion of the second ethylene cycles through the first and second polymerization zones and a gas mixture of each polymerization zone is partially or totally prevented from entering the other zone. | 2014-08-28 |
20140243476 | MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PREPARING THE SAME - Disclosed are a modified conjugated diene polymer and a method for preparing the same. The modified conjugated diene polymer and the method for preparing the same advantageously provide superior compatibility with an inorganic filler, heat generation, tensile strength and abrasion resistance, low fuel consumption and excellent resistance on wet roads. | 2014-08-28 |
20140243477 | ADDITIVES FOR STABILIZING POLYMERS WITH RESPECT TO HYDROLYSIS - Use of copolymers (C) comprising at least one epoxy group and at least one alkoxysilane group as stabilizers for polymers (P), where the copolymers (C) are generally obtained via polymerization of monomers and said monomers comprise those that comprise epoxy groups or alkoxysilane groups or epoxy groups and alkoxysilane groups, or that are reacted during or after polymerization and, after the reaction, comprise epoxy groups or alkoxysilane groups, or epoxy groups and alkoxysilane groups. Processes for stabilizing polymers (P) with respect to hydrolysis, which comprise adding, to the polymers (P), an effective amount of copolymers (C). Copolymers (C′) composed of specific compositions of monomers comprising at least one epoxy group and at least one alkoxysilane group, and also optionally other monomers. Mixtures comprising copolymers (C′) and polymers (P). | 2014-08-28 |
20140243478 | METHOD FOR PRODUCING WATER ABSORBENT RESIN PARTICLES - There is disclosed a method for producing water-absorbent resin particles, comprising a polymerization step that includes mixing an oily liquid comprising a hydrocarbon dispersing medium and a surfactant, and an aqueous liquid comprising an aqueous solvent and a water-soluble ethylenically unsaturated monomer, forming a suspension comprising an oily liquid and an aqueous liquid dispersed in the oily liquid, and polymerizing the water-soluble ethylenically unsaturated monomer in the suspension. The HLB of the surfactant is 6 or greater, and the temperature of the suspension is kept at 35° C. or higher during the period from initial mixing of the oily liquid and aqueous liquid until complete mixing of the entire amounts. | 2014-08-28 |
20140243479 | THICKENING VINYL COPOLYMERS - A rheology modifier copolymer of formula (I) wherein A is a macromonomer, B is an acrylic or methacrylic acid or salt thereof, C is a C | 2014-08-28 |
20140243480 | NOVEL ANIONIC POLYMERIZATION INITIATOR, USE THEREOF FOR SYNTHESIZING A DIENE ELASTOMER HAVING AN ALKYNE FUNCTION AT THE CHAIN END, AND FUNCIONALIZED DIENE ELASTOMER - An anionic polymerization initiator of formula: | 2014-08-28 |
20140243481 | Manufacturing Process for Liquid Crystalline Polymer - The properties of a liquid crystalline polymer (LCP) containing ester linkages and made in the presence of an excess of diol are improved by treating the LCP with a dicarboxylic acid at elevated temperature. The resulting LCPs are useful as molding resins and for films. | 2014-08-28 |
20140243482 | POLYAMIDE-IMIDE COPOLYMER FILM AND METHOD OF PREPARING POLYAMIDE-IMIDE COPOLYMER - Disclosed herein is a polyamide-imide copolymer film, comprising a copolymer resin in which a unit structure derived from TFDB (2,2′-bistrifluoromethyl-4,4′-biphenyl diamine), a unit structure derived from 6FDA (4,4′-(hexa-fluoroisopropylidene)diphthalic anhydride), a unit structure derived from BPDA (3,3′,4,4′-biphenyltetracarboxylic dianhydride) and a unit structure derived from TPC (terephthaloyl chloride or 1,4-benzenedicarbonyl chloride) are copolymerized, wherein the copolymer resin has a weight average molecular weight of 10,000˜400,000. | 2014-08-28 |
20140243483 | Chiral Polymers for the Self-Assembly of Photonic Crystals - Described herein are copolymers constructed from chiral, non-racemic monomers, which self-assemble to photonic crystals. The difficulty of incorporating chiral elements into photonic crystals has limited the ability to generate unique bandstructures for different circular polarizations of light. The materials and methods described herein relate to easily, predictably fabricating chiral photonic crystals having desirable optical properties. | 2014-08-28 |
20140243484 | Masked Polyisocyanate and Uses Thereof - The invention relates to polyurethane resin compositions and, in particular, stable, ready-to-use polyurethane resin compositions comprising: a masked polyisocyanate having formula (I), wherein B represents alkyl and A represents a group comprising a number of isocyanate functions of between 1.5 and 2.2, preferably between 1.5 and 2.1 and, more preferably, between 1.5 and 2; or a masked pre-polymer that is the product of a reaction between the above-mentioned masked polyisocyanate and a polyol having between 1.5 and 3 OH functions and a molecular mass of between 900 and 3,000 g/mol, in a ratio such that the number of NCO functions of the masked polyisocyanate in relation to the number of OH functions of the polyol is between 1.5 and 2.5 approximately; or a mixture of the aforementioned masked polyisocyanate and masked pre-polymer. The invention also relates to the use of the masked polyisocyanate in order to form a masked pre-polymer by reacting said masked polyisocyanate on a polyol, and to the use of a masked polyisocyanate and/or a masked pre-polymer in polyurethane resin compositions. | 2014-08-28 |
20140243485 | High Performance Polymer Composition with Improved Flow Properties - A polymer composition that contains at least one high performance polymer and at least one aromatic amide oligomer is provided. The oligomer can serve as a flow aid that lowers the overall viscosity of the polymer matrix under shear. | 2014-08-28 |
20140243486 | REUSABLE HOMOGENEOUS COBALT PYRIDINE DIIMINE CATALYSTS FOR DEHYDROGENATIVE SILYLATION AND TANDEM DEHYDROGENATIVE-SILYLATION-HYDROGENATION - Disclosed herein are cobalt complexes containing terdentate pyridine di-imine ligands and their use as efficient, reusable, and selective dehydrogenative silylation, crosslinking, and tandem dehydrogenative silylation-hydrogenation catalysts. | 2014-08-28 |
20140243487 | PROCESS FOR CROSSLINKING A POLYMER COMPRISING PYRIDYL GROUPS - The present invention relates to process for crosslinking an arylene oxide polymer comprising a 3-pyridyl and/or a 4-pyridyl group, wherein the polymer is reacted with a compound according to Formula (1) or a compound according to Formula (2), wherein R | 2014-08-28 |
20140243488 | METHOD FOR PRODUCING CONJUGATED POLYMER, CONJUGATED POLYMER, PHOTOELECTRIC CONVERSION ELEMENT, SOLAR CELL, AND SOLAR CELL MODULE - The invention addresses a problem of obtaining a conjugated polymer having a higher molecular weight through coupling reaction of monomers using a transition metal catalyst. The invention relates to a method for producing a conjugated polymer, which comprises polymerizing one or more monomers through a coupling reaction, wherein the coupling reaction of the monomer is carried out by using one or more kinds of homogeneous transition metal complex catalysts and one or more kinds of heterogeneous transition metal complex catalysts in combination. | 2014-08-28 |
20140243489 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS - Catalyst component for the polymerization of olefins comprising Mg, Ti and an electron donor compound of the following formula (I) | 2014-08-28 |
20140243490 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS - Catalyst component for the polymerization of olefins comprising Mg, Ti and an electron donor compound of the following formula (I) | 2014-08-28 |
20140243491 | Half-Metallocene Compounds and Catalyst Compositions - The present invention provides polymerization catalyst compositions employing half-metallocene compounds with a heteroatom-containing ligand bound to the transition metal. Methods for making these hybrid metallocene compounds and for using such compounds in catalyst compositions for the polymerization of olefins also are provided. | 2014-08-28 |
20140243492 | METHOD FOR PRODUCING CONDENSED POLYCYCLIC AROMATIC COMPOUND, AND CONJUGATED POLYMER - The invention addresses a problem of purifying a monomer to be a precursor according to a simpler and milder method so as to obtain a polymer having a higher molecular weight. The invention relates to a method for producing a condensed polycyclic aromatic compound having n active groups (wherein n is an integer of 1 or more and 4 or less), which comprises bringing a composition containing the condensed polycyclic aromatic compound and a solvent into contact with zeolite. | 2014-08-28 |
20140243493 | (METH) ACRYLATE RESIN COMPOSITION AND CURED PRODUCT OF SAME - A (meth)acrylate resin composition of the present invention contains: a (meth)acrylic resin composition (A) containing a (meth)acrylic acid ester and a poly(meth)acrylic acid ester; and a crosslinking agent (B) containing a bifunctional (meth)acrylic monomer (C) represented by chemical formula 1 and a polyfunctional unsaturated ester compound (D) containing three or more radically polymerizable functional groups. The bifunctional (meth)acrylic monomer (C) is contained in an amount of 2 to 25 parts by mass and the polyfunctional unsaturated ester compound containing three or more radically polymerizable functional groups is contained in an amount of 0.1 to 5 parts by mass, based on 100 parts by mass of the (meth)acrylic resin composition (A). | 2014-08-28 |
20140243494 | Method for Preparing a Diorganodihalosilane - A method of preparing a diorganodihalosilane, the method comprising the following separate and consecutive steps: (a) treating a metal catalyst comprising a metal selected from the groups consisting of i) gold, ii) gold and copper, iii) gold, copper and magnesium, iv) copper, rhodium and gold, v) copper, rhodium, and rhenium, vi) rhenium and palladium, vii) copper, and viii) copper and magnesium with a mixture comprising hydrogen gas and an organotrihalosilane at a temperature from 500 to 1400° C. to form a silicon-containing metal intermediate; and (b) reacting the silicon-containing metal intermediate with an organohalide according to the formula RX, wherein R is C | 2014-08-28 |
20140243495 | POLYETHER PREPARATION METHOD, PREPOLYMER PREPARATION METHOD, AND MODIFIED SILICONE POLYMER PREPARATION METHOD - A polyether preparation method which comprises a polymerization step of subjecting a monoepoxide having at least 2 carbon atoms to ring-opening addition polymerization to an initiator having at least one active hydrogen-containing functional group in the presence of a catalyst in a stirring vessel, to obtain a polyether, wherein the stirring vessel is one wherein a stirring shaft rotatable by an external drive source is provided at the center of the stirring vessel; plate-shaped bottom paddles extending in a radial direction of the stirring vessel are mounted on a lower portion of the stirring shaft; lattice vanes each comprising arm paddles extending in a radial direction and strips extending in an axial direction, are mounted on a portion of the stirring shaft above the bottom paddles; and a discharge nozzle as a monoepoxide-supply means for discharging the monoepoxide to at least two locations below the lower ends of the strips. | 2014-08-28 |
20140243496 | URETHANE-BASED OPTICAL COMPONENT AND MANUFACTURING PROCESS THEREFOR - The present invention relates to a urethane optical member containing at least one kind of structures represented by the following formulae (1) and (2) in a structure constituting the optical member, and a method for producing the same. | 2014-08-28 |
20140243497 | PROCESS FOR PREPARING HIGHLY ACTIVE DOUBLE METAL CYANIDE CATALYSTS AND THEIR USE IN THE SYNTHESIS OF POLYETHER POLYOLS - The present invention relates to a process of preparing a double metal cyanide (DMC) complex catalyst with an improved catalytic activity useful for epoxide polymerization. It also relates to the DMC catalyst obtainable by said process, as well as to polyether polyols prepared by a polymerization reaction using said DMC catalyst. | 2014-08-28 |
20140243498 | METHOD FOR PURIFICATION OF CLEAVED PRO-INSULIN - The present invention is within the field of biomolecule purification. More closely the invention relates to chromatographic purification of insulin using a specific kind of shell beads having an inner core and an outer functionalized layer. The method enables purification at high flow rates and high purity, over 90%. | 2014-08-28 |
20140243499 | PEPTIDE DERIVATIVES AND USE THEREOF AS CARRIERS FOR MOLECULES IN THE FORM OF CONJUGATES - The invention relates to peptide derivatives (peptides and pseudo-peptides) and use thereof as vectors for molecules of interest. The invention also relates to conjugates containing a peptide derivative of the invention bound to a molecule of interest. The peptides and prodrug conjugates of the invention can be used to vectorise molecules of pharmaceutical or diagnostic interest, such as, for example, therapeutic molecules, imaging or diagnostic agents, or molecular probes, across cell membranes, and notably to promote their transport across the blood-brain barrier (BBB). | 2014-08-28 |
20140243500 | CALIBRATION AND NORMALIZATION SYSTEMS AND METHODS FOR RADIOPHARMACEUTICAL SYNTHESIZERS - The present invention relates to calibration and normalization systems and methods for ensuring the quality of radiopharmaceuticals during the synthesis thereof, such as radiopharmaceuticals used in Positron Emission Tomography (PET) and Single-Photon Emission Computed Tomography (SPECT). | 2014-08-28 |
20140243501 | HISTONE DEACETYLASE INHIBITORS AND SYNTHETIC METHOD THEREOF AND USE THEREOF IN MANUFACTURE OF MEDICAMENTS - The invention provides histone deacetylase (HDAC) inhibitors shown as Formula I, where R | 2014-08-28 |
20140243502 | Anticoagulation agent and uses thereof - The present invention provides an anticoagulant agent including a first element capable of inhibiting coagulation and a second element capable of targeting an activated platelet wherein upon administration of the agent to a subject the second element directs the first element to the activated platelet. Also provided is a probe for detecting a blood vessel abnormality including (a) a binding element capable of targeting an activated platelet and (b) a label. Applicant has shown that agents and probes directed to activated platelets are useful in the diagnosis and therapy of coagulation disorders. | 2014-08-28 |