35th week of 2014 patent applcation highlights part 49 |
Patent application number | Title | Published |
20140242499 | LIGHT-REFLECTIVE PHOTOMASK AND MASK BLANK FOR EUV EXPOSURE, AND MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE - According to one embodiment, a light-reflective photomask including a circuit pattern area, and an outside area positioned outside the circuit pattern area includes a substrate, a low-reflectivity layer provided in both the circuit pattern area, and the outside area, formed on the substrate, including at least a conductive layer, and comprising a first reflectivity for deep ultraviolet light, a multilayer reflection layer provided in the circuit pattern area, and formed on the low-reflectivity layer, and a light-absorber provided in the circuit pattern area, formed on the multilayer reflection layer, including a circuit pattern, and comprising a second reflectivity for deep ultraviolet light. The first reflectivity is lower than or equal to the second reflectivity. | 2014-08-28 |
20140242500 | Process For Cleaning Shield Surfaces In Deposition Systems - A process for cleaning and restoring deposition shield surfaces which results in a cleaned shield having a surface roughness of between about 200 microinches and about 500 microinches and a particle surface density of less than about 0.1 particles/mm | 2014-08-28 |
20140242501 | Coating Of Shield Surfaces In Deposition Systems - A deposition chamber shield having a stainless steel coating of from about 100 microns to about 250 microns thick wherein the coated shield has a surface roughness of between about 300 microinches and about 800 microinches and a surface particle density of less than about 0.1 particles/mm | 2014-08-28 |
20140242502 | ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY- OR RADIATION-SENSITIVE FILM, MASK BLANK AND METHOD OF FORMING PATTERN - According to one embodiment, an actinic-ray- or radiation-sensitive resin composition includes a compound (A) that contains a structure (P) containing at least one phenolic hydroxyl group and a structure (Q) containing at least one phenolic hydroxyl group whose hydrogen atom is replaced by a group (S) with a cyclic structure containing an acid crosslinking group, characterized in that the group (S) with a cyclic structure containing an acid crosslinking group is a group with a polycyclic structure or a group with a cyclic structure containing a hydroxymethyl group and/or an alkoxymethyl group. | 2014-08-28 |
20140242503 | METHOD OF MANUFACTURING A COLOR FILTER - A color filter is manufactured on each of a plurality of light-receiving elements of an RGB sensor using a plurality of kinds of light-transmitting films having different transmission colors. In such a case, the light-transmitting film that is to be coated next does not uniformly spread across the entire semiconductor wafer, and coating nonuniformities readily occur when a pattern of the light-transmitting film formed earlier on a certain optical element has a right angle portion. In order to solve this problem, the pattern of the light-transmitting film formed earlier has a planar shape having corner-cut portions so that right angle portions do not occur. | 2014-08-28 |
20140242504 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION AND METHOD FOR FORMING PATTERNS BY USING THE SAME - The present invention relates to a positive photosensitive resin composition and a method for forming patterns by using the same. The positive photosensitive resin composition includes a novolac resin (A), an ortho-naphthoquinone diazide sulfonic acid ester (B), a hydroxycompound (C) and a solvent (D). The novolac resin (A) further includes a hydroxy-type novolac resin (A-1) and a xylenol-type novolac resin (A-2). The hydroxy-type novolac resin (A-1) is synthesized by condensing hydroxyl benzaldehyde compound with aromatic hydroxyl compound. The xylenol-type novolac resin (A-2) is synthesized by condensing aldehyde compound with xylenol compound. The postbaked positive photosensitive resin composition can be beneficially formed to patterns with high film thickness and well cross-sectional profile. | 2014-08-28 |
20140242505 | PATTERN FORMING METHOD, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, MANUFACTURING METHOD OF ELECTRONIC DEVICE, AND ELECTRONIC DEVICE - A pattern forming method including: (i) a process of forming a film using an actinic ray-sensitive or radiation-sensitive resin composition containing a Resin (P) including a non-acid-decomposable Repeating Unit (b1) represented by a following General Formula (b1) and a repeating unit including a group capable of being decomposed by acid and generating a polar group, and a Compound (B) capable of generating an acid through irradiation of actinic rays or irradiation; (ii) a process of exposing the film using actinic rays or radiation with a wavelength of equal to or less than 200 nm; and (iii) a process of developing the exposed film using a developer including an organic solvent containing a hetero atom and carbon atoms having 7 or more carbon atoms to forming a negative tone pattern. | 2014-08-28 |
20140242506 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS - A surface layer of the electrophotographic photosensitive member has a change region in which a ratio of the number of carbon atoms with respect to the sum of the number of silicon atoms and the number of carbon atoms gradually increases toward a surface side of the electrophotographic photosensitive member from a photoconductive layer side, wherein the change region has an upper charge injection prohibiting portion containing a Group 13 atom, and a surface-side portion which is positioned closer to the surface side of the electrophotographic photosensitive member than the upper charge injection prohibiting portion and does not contain the Group 13 atom, and the distribution of the Group 13 atom in a boundary portion between the surface-side portion and the upper charge injection prohibiting portion is precipitous. | 2014-08-28 |
20140242507 | POSITIVELY CHARGEABLE SINGLE-LAYER ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER AND IMAGE FORMING APPARATUS - A positively chargeable single-layer electrophotographic photosensitive member includes a single-layer photosensitive layer. The single-layer photosensitive layer contains a charge generating material, a hole transport material, an electron transport material, and a binder resin. The electron transport material contains two or more compounds selected from the group consisting of compounds represented by the chemical formulas (1) to (4) below. | 2014-08-28 |
20140242508 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME - An electrophotographic photoreceptor includes a cylindrical base and a photosensitive layer disposed on the cylindrical base. The photosensitive layer has a photoconductive layer disposed on the cylindrical base, a charge injection blocking layer disposed on the photoconductive layer, and a surface layer disposed on the charge injection blocking layer. The charge injection blocking layer contains at least one of nitrogen and oxygen, carbon, and a group 13 element. A content of the at least one of nitrogen and oxygen contained in the charge injection blocking layer is lower on a side of the surface layer than on a side of the photosensitive layer. | 2014-08-28 |
20140242509 | ELECTROSTATIC LATENT IMAGE DEVELOPING TONER AND METHOD FOR PRODUCING ELECTROSTATIC LATENT IMAGE DEVELOPING TONER - An electrostatic latent image developing toner containing a plurality of toner particles, each including a binder resin and a release agent, is provided. The surface hardness of the toner particle, measured by a nanoindentation method, satisfies the following conditions (1) and (2): (1) The surface hardness of the toner particle attained with a displacement of 10 nm is 1 GPa or more and 3 GPa or less; and (2) the surface hardness of the toner particle attained with a displacement of 100 nm is 1 GPa or less. | 2014-08-28 |
20140242510 | TWO-COMPONENT COLOR DEVELOPER AND IMAGE FORMATION DEVICE USING SAME - A two-component color developer containing a toner and a resin-coated carrier, the toner containing at least a polyester resin as a binding resin, an organic pigment as a colorant and inorganic fine particles as an external additive, wherein the inorganic fine particles have a negative polarity, the toner has a volume resistivity of 40×10 | 2014-08-28 |
20140242511 | METHOD FOR MANUFACTURING CARRIER CORE PARTICLES FOR ELECTROPHOTOGRAPHIC DEVELOPER, CARRIER CORE PARTICLES FOR ELECTROPHOTOGRAPHIC DEVELOPER, CARRIER FOR ELECTROPHOTOGRAPHIC DEVELOPER, AND ELECTROPHOTOGRAPHIC DEVELOPER - Provided is a method for manufacturing carrier core particles for electrophotographic developer capable of stably maintaining high chargeability over a long time. The method for manufacturing carrier core particles includes a granulation step of granulating a mixture of raw materials containing manganese, iron, strontium, and calcium and a firing step of firing the mixture granulated in the granulation step. The firing step includes a heating process of heating the granular mixture with an increase in temperature to a predetermined degree and a cooling process of cooling the granular mixture, after the heating process, in an atmosphere with an oxygen concentration ranging from 5000 ppm to 20000 ppm. The molar ratio of the sum of strontium and calcium to the sum of the manganese, iron, strontium, and calcium is 0.0026 to 0.013. | 2014-08-28 |
20140242512 | LIQUID DEVELOPER, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, LIQUID DEVELOPER CARTRIDGE, AND PROCESS CARTRIDGE - There is provided a liquid developer containing a toner that has a ratio G′ (65)/G′(90) of a storage modulus G′ (65) at 65° C. to a storage modulus G′ (90) at 90° C. of from 1×10 | 2014-08-28 |
20140242513 | LIQUID DEVELOPER, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, LIQUID DEVELOPER CARTRIDGE, AND PROCESS CARTRIDGE - There is provided a liquid developer containing a toner that has a ratio G′(65)/G′(90) of a storage modulus G′(65) at 65° C. to a storage modulus G′(90) at 90° C. of from 1×10 to 1×10 | 2014-08-28 |
20140242514 | PARTICULATE MATERIAL PRODUCTION METHOD, AND PARTICULATE MATERIAL PRODUCTION APPARATUS - A particulate material production method is provided. The particulate material production method includes ejecting a particulate material composition liquid, which includes an organic solvent and a particulate material composition including at least a resin and dissolved or dispersed in the organic solvent, from at least one nozzle to form droplets of the particulate material composition liquid in a gas phase; and solidifying the droplets of the particulate material composition liquid to prepare particles of the particulate material composition. The droplet solidifying step includes contacting the droplets with a poor solvent for the particulate material composition. | 2014-08-28 |
20140242515 | PHOTORESIST COMPOSITION AND METHOD OF MANUFACTURING DISPLAY DEVICE USING SAME - A photoresist composition including a binder resin including a novolac resin represented by Chemical Formula 1, a diazide photosensitive initiator, and a solvent including a base solvent and an auxiliary solvent, wherein the base solvent includes propylene glycol monomethyl ether acetate, and the auxiliary solvent includes dimethyl-2-methylglutarate and ethyl beta-ethoxypropionate, | 2014-08-28 |
20140242516 | Silane Composition and Cured Film Thereof, and Method for Forming Negative Resist Pattern Using Same - A composition provided to contain:
| 2014-08-28 |
20140242517 | LITHOGRAPHIC PRINTING PLATE PRECURSORS AND USE - Negative-working lithographic printing plate precursor a negative-working imageable layer and an outermost water-soluble overcoat layer that is disposed directly on the negative-working imageable layer. The outermost water-soluble overcoat layer comprises: (1) one or more film-forming water-soluble polymeric binders, (2) organic wax particles, and (3) non-wax matte particles. The outermost water-soluble overcoat layer has a dry thickness (t) that is defined by the following equation (I): | 2014-08-28 |
20140242518 | PATTERNING PROCESS AND RESIST COMPOSITION - A negative pattern is formed by applying a resist composition onto a substrate, prebaking, exposing to high-energy radiation, baking (PEB), and developing the exposed resist film in an organic solvent developer to dissolve the unexposed region of resist film. The resist composition comprising a polymer comprising recurring units of cycloolefin having a hydroxyl group substituted with an acid labile group, an acid generator, and an organic solvent displays a high dissolution contrast and high etch resistance. | 2014-08-28 |
20140242519 | MONOMER, POLYMER, RESIST COMPOSITION, AND PATTERNING PROCESS - A polymer for resist use is obtainable from a monomer having formula (1) wherein R | 2014-08-28 |
20140242520 | I-LINE PHOTORESIST COMPOSITION AND METHOD FOR FORMING FINE PATTERN USING SAME - An I-line photoresist composition, having excellent thermal stability at high temperature of 200-250° C., by which fine photoresist patterns form using an acid diffusion layer and a method for forming a fine pattern using the same, comprising: a polymer containing 1-99 mol % of repeating unit selected from a group consisting of 1-99 mol % of repeating unit represented by Formula 1, repeating unit represented by Formula 2, repeating unit represented by Formula 3 and mixture thereof; a photo active compound containing at least two diazonaphtoquinone (DNQ) groups; and an organic solvent. Formulas 1-3 are located in the specification. R* and R** are independently a hydrogen atom or a methyl group. R | 2014-08-28 |
20140242521 | PHOTOSENSITIVE COPOLYMER, PHOTORESIST COMPRISING THE COPOLYMER, AND METHOD OF FORMING AN ELECTRONIC DEVICE - A copolymer includes the polymerized product of a comonomer and a monomer having the formula (I): | 2014-08-28 |
20140242522 | DOUBLE-MASK PHOTOLITHOGRAPHY METHOD MINIMIZING THE IMPACT OF SUBSTRATE DEFECTS - In the field of photolithography and, notably, photolithography in the extreme ultraviolet, a photolithography method is provided in which a first mask blank is produced that can have defects, an individual mapping of the positions of the defects of this mask blank is established using an inspection machine, and, for each defect, an exclusion zone is defined around the defect. Then, two complementary masks are produced, one with the first mask blank and with the desired design pattern, except in the exclusion zones, the latter being black, the other with a second mask blank and with the desired design pattern parts in the exclusion zones, all the rest of the second mask being black. The exposure of the surface to be processed by photolithography is done in two successive steps using the two complementary masks. | 2014-08-28 |
20140242523 | Techniques For Patterning A Substrate - Various techniques for patterning a substrate are disclosed. Specifically, implantation of the first species into an anti-reflective coating layer is contemplated to reduce stress in the layer that may be generated during the exposure stage or development stage. During these steps, the resist layer or the resist structure may under mechanical changes (e.g. shrinkage) while it is in contact with the anti-reflective layer. Such changes may introduce stress in the anti-reflective layer, which may contribute to excessive line edge roughness (LER) or line width roughness (LWR). By implanting the first species before, during, or after these steps, the stress in the anti-reflective layer may be avoided or compensated, and excessive LER or LWR may be avoided or reduced. | 2014-08-28 |
20140242524 | TWO MASK PROCESS FOR ELECTROPLATING METAL EMPLOYING A NEGATIVE ELECTROPHORETIC PHOTORESIST - A negative electrophoretic photoresist is applied over a plurality of protruding disposable template portions on a substrate. A silo structure is placed on planar portions of the negative electrophoretic photoresist that laterally surround the plurality of protruding disposable template portions. The negative electrophoretic photoresist is lithographically exposed employing the silo structure and a first lithographic mask, which includes a transparent substrate with isolated opaque patterns thereupon. After removal of the silo structure, the negative electrophoretic photoresist is lithographically exposed employing a second lithographic mask, which includes a pattern of transparent areas overlying the planar portions of the negative electrophoretic photoresist less the areas for bases of metal structure to be subsequently formed by electroplating. The negative electrophoretic photoresist is developed to form cavities therein, and metal structures are formed by electroplating within the cavities. The negative electrophoretic photoresist and the plurality of protruding disposable template portions can be subsequently removed. | 2014-08-28 |
20140242525 | PATTERNING OF TRANSPARENT CONDUCTIVE COATINGS - A method of patterning a conductive polymer includes providing a conductive polymer layer coated over a first support followed by pattern-wise transferring a layer containing polyvinyl acetal from a second support onto the conductive polymer to form a mask with at least one opening. The masked conductive polymer is subjected to treatment through the opening that changes the conductivity of the conductive polymer by at least one order of magnitude in areas not covered by the mask. | 2014-08-28 |
20140242526 | POSITIVE TONE ORGANIC SOLVENT DEVELOPED CHEMICALLY AMPLIFIED RESIST - Provided is a method for developing positive-tone chemically amplified resists with an organic developer solvent having at least one polyhydric alcohol, such as ethylene glycol and/or glycerol, alone or in combination with an additional organic solvent, such as isopropyl alcohol, and/or water. The organic solvent developed positive tone resists described herein are useful for lithography pattern forming processes; for producing semiconductor devices, such as integrated circuits (IC); and for applications where basic solvents are not suitable, such as the fabrication of chips patterned with arrays of biomolecules or deprotection applications that do not require the presence of acid moieties. | 2014-08-28 |
20140242527 | REDUCED EMISSIONS COMBUSTOR - Embodiments of this invention relate generally to furnaces, particularly to furnaces with combustors utilizing fuel and oxidizer jets, more particularly to furnaces used for glass production, and further to glass container production. In one embodiment, a furnace comprises first and second opposing walls, the first wall including a fuel nozzle having a fuel nozzle centerline extending toward the second wall, and an oxidizer nozzle having an oxidizer nozzle centerline extending toward the second wall and an oxidizer jet boundary. The first and second opposing walls are separated by a wall separation distance L. In this embodiment, the fuel nozzle centerline intersects the oxidizer jet boundary at a crossing distance x | 2014-08-28 |
20140242528 | Support system for radiant tube heaters - A modular support system for outdoor radiant tube heaters includes a frame defined by hollow beams for receiving fuel and electrical lines and supporting electrical heaters posts for supporting the beams and saddles for interconnecting the beams and mounting them on posts. | 2014-08-28 |
20140242529 | TORCH AND TORCH ATTACHMENT - An attachment for a torch includes a combustion cone mounted on a fuel delivery tube. The combustion cone bounds a combustion chamber and has an inlet through which fuel from the tube enters the chamber to create a flame when the torch ignites the fuel. The cone diverges away from the inlet and to an outlet to enable the flame to diverge and spread within the chamber. The chamber substantially contains the flame therein. At least one apertured radiator, and preferably, a pair of apertured radiators, is mounted in the chamber in direct contact with the flame, and heated by the flame to a temperature sufficient to cause each radiator to radiate infrared radiation through and past the outlet. A tipping-resistant holder holds a fuel canister of the torch upright when placed on a support surface. | 2014-08-28 |
20140242530 | SUBSTRATE HEAT TREATMENT APPARATUS AND METHOD - Substrate heat treatment apparatus and method are provided. According to an embodiment of the present invention, there is provided a substrate heat treatment apparatus including an inner shell configured to form a substrate housing space to house at least one substrate, an outer shell configured to cover the inner shell, and having at least one gas hole, and at least one heater configured to heat the substrate, wherein the at least one gas hole is configured to allow a first gas to be injected into a space between the inner shell and the outer shell. | 2014-08-28 |
20140242531 | REACTION CONTAINER AND VACUUM HEAT TREATMENT APPARATUS HAVING THE SAME - A method of fabricating a reaction container according to the disclosure comprises putting graphite power in a molded member; and pressing the molded member, wherein the graphite powder comprises first graphite powder and second graphite powder having different particle sizes. A vacuum heat treatment apparatus comprises a chamber, a reaction container in the chamber, and a heat member heating the reaction container in the chamber, in which the reaction container comprises graphite, and the reaction container has a concentration in the range of 1.8 to 2.0. | 2014-08-28 |
20140242532 | METHOD FOR ORTHODONTIC TREATMENT - A method for orthodontic treatment includes defining a plurality of incremental tooth adjustment stages. Each tooth adjustment stage includes an incremental change in an alignment of at least one tooth. The tooth adjustment stages include a final stage. For one of the stages prior to the final stage, the method includes sequentially utilizing a plurality of orthodontic appliances, each appliance having identical tooth geometries configured to the stage, wherein a final orthodontic appliance for the stage is a rigid tray configured to immobilize the tooth for a recuperation period. | 2014-08-28 |
20140242533 | AESTHETIC ORTHODONTIC BRACKET AND METHOD OF MAKING SAME - An orthodontic bracket for coupling an archwire with a tooth includes a bracket body that has an archwire slot adapted to receive the archwire. A movable member is engaged with the bracket body and is movable between an opened position and a closed position. The bracket body and movable member are made from a transparent or translucent ceramic for improved aesthetics. The bracket body may include one or more stop surfaces that limit movement of the moveable member in the gingival direction. The bracket body may include a support surface that is positioned lingually of a labial edge of the archwire slot. The moveable member may include a bracket-engaging portion having a first surface confronting the bracket body and a slot-covering portion having a second surface confronting the archwire slot, the first and second surfaces being offset from one another. | 2014-08-28 |
20140242534 | MANDIBULAR ATTACHMENT FOR CORRECTION OF MALOCCLUSION - Mandibular attachment structure for use in an orthodontic assembly having a force member connecting the mandibular and maxillar portions of the assembly and method of using the same. The structure includes bands dimensioned to encircle corresponding lower molars on opposite sides of the tongue, and threadless couplers each of which is removably or releasably affixed to a buccal side of a corresponding band. Neither the structure nor the method requires the use of an orthodontic brace to maintain a pressing connection between the structure and the rest of an orthodontic assembly, but the use of orthodontic braces is accommodated. The pressing connection is maintained by cooperating a hook at the end of the force member and a hook at the end of a threadless coupler. | 2014-08-28 |
20140242535 | FLUORIDE RELEASING BITE PLATE - The present disclosure relates to biteplates for use with various orthodontic remodeling devices, wherein the bite plate releases fluoride during use, thus encouraging remineralization on enamel. Additionally, bite plates with a colorant or color-changing matrix that serve as indicators for fluoride concentration are also described. | 2014-08-28 |
20140242536 | MANDIBULAR ATTACHMENT FOR CORRECTION OF MALOCCLUSION - Mandibular attachment structure, devoid of elastomeric member, for use in an orthodontic assembly having a force member connecting the mandibular and maxillar portions of the assembly and method of using the same. The structure includes bands dimensioned to encircle corresponding lower molars on opposite sides of the tongue, a single arched member connecting the bands and extending along a lingual side of the lower teeth, and threadless couplers each of which is affixed to a labial side of a corresponding band. Neither the structure nor the method require the use of an orthodontic brace to maintain a pressing connection between the structure and the rest of an orthodontic assembly. The pressing connection is maintained by cooperating a hook at the end of the force member and a hook at the end of a threadless coupler. | 2014-08-28 |
20140242537 | STERILE PTFE STRIPS WITH APPLICATION TAB - A dental treatment apparatus is disclosed that may include a PTFE strip and at least one applicator tab attached to the PTFE strip wherein the applicator tab can be pulled away from the PTFE strip under the discretion of an operator. The applicator tab may comprise at least one adhesive surface limited to an area of the application tab which is used for attaching the application tab to the PTFE strip. The PTFE strip and the applicator tab may comprise varying shapes, widths, and lengths based on its desired application. | 2014-08-28 |
20140242538 | RADIATION SOURCE AND LIGHT GUIDING DEVICE - The invention relates to a radiation source, in particular a light curing device, for the polymerization of dental materials, comprising a light conductor and a light generation device which has at least two light sources, preferably semiconductor light sources, in particular light diodes, and the radiation of which is bundled by a reflector and fed into the light conductor. The light sources differ from one another with respect to their light color and/or their emission spectrum and are controllable separately for changing the light color and/or the emission spectrum and/or the spectral radiant power of the radiation emitted. The light conductor has at least one monocore section and one multicore section wherein the radiation emitted by the light sources is fed into a monocore section of the light conductor. Further, the invention relates to a light-conducting device for a radiation source or a light curing device of this kind. | 2014-08-28 |
20140242539 | VIRTUAL DESIGN OF ATTACHMENT OF DENTAL MODEL IN ARTICULATOR - Disclosed is a method for virtually designing the attachment of a manufactured dental model of a patient's set of teeth in a physical dental articulator by means of one or more kinds of spacer elements, where the method comprises:
| 2014-08-28 |
20140242540 | METHODS OF MAKING AN IMPRESSION OF DENTAL TISSUE AND DENTAL ARTICLES - Methods of making an impression of dental tissue and dental articles (e.g. suitable for dental impression) are described. In one embodiment, the method comprises providing a hardenable composition, comprising a resin system, a filler system, and an initiator system wherein the hardenable composition is a hardenable self-supporting material having sufficient malleability to be formed into a shape. The method further comprises placing said hardenable composition in contact with dental tissue such that an impression of at least a portion of the dental tissue is formed in the hardenable composition. The method further comprises curing the hardenable composition comprising the impression. | 2014-08-28 |
20140242541 | DENTAL CUTTING SYSTEM AND METHOD WITH REMOTE CUTTING GUIDE - A dental cutting system and method for cutting a patient's tooth includes a hand piece to be held and carrying a cutting burr to cut the patient's tooth. A plurality of guide pins is attached to and extends from the hand piece of the cutting tool remote from the cutting bur. One or more cutting guides each have a cavity coinciding with at least a portion of teeth inside a patient's mouth that are adjacent to or remote from the patient's tooth to be cut. The guide pins of the handpiece slide in slots in the cutting guide to guide the cutting burr to cut the patient's tooth. | 2014-08-28 |
20140242542 | Dental Handpiece Rack and Method of Storing Dental Handpieces - A dental handpiece and general implement rack is provided, along with a method of tracking implement use in a patient environment. The rack comprises a housing having a plurality of removable trays therein, the trays being adapted to support a dental implement thereon. Each tray includes a visual indicator that matches a marker placed on an implement being stored in that tray. The tray indicators are utilized to determine which implement has been utilized during the course of the day in order to implement sterilization procedures for only those implements that have been used on patients and are now unsterile. The device and associated method prevent sterilization by autoclave for implements that do not require cleaning, thereby extending their useful life and preventing over-cleaning thereof. The housing is preferably a wall-mountable structure having a hinged lid closure and a ventilated design to prevent moisture capture therein. | 2014-08-28 |
20140242543 | Fatigue-Resistant Nitinol Instrument - A fatigue-resistant Nitinol instrument has a working portion in the deformed monoclinic martensitic state and an austenite finish temperature in the range of 40° to 60° C. Because the operating environment of the instrument is about 37° C., the working portion remains in the monoclinic martensitic state during its use. The relatively high austenite finish temperature and fatigue resistance is achieved by subjecting the nickel-titanium alloy to a final thermal heat treat in a temperature range of about 410° to 440° C. while the nickel-titanium alloy is under constant strain of about 3 to 15 kg. Further, the high austenite finish temperature is achieved without subjecting the alloy to thermal cycling to produce shape memory. Additionally, there are no intermediate processing steps occurring between obtaining a finished diameter of the wire or blank through cold working and the final thermal heat treat under constant strain. | 2014-08-28 |
20140242544 | Matrix Ring for Tooth Restoration - A matrix ring comprising includes a biasing ring and a pair of opposing tines. The biasing ring includes a substantially hoop-like configuration terminating at two opposing ends. The pair of opposing tines extend inwardly from each of the two ends of the biasing ring toward each other. Each of the pair of opposing tines is coupled to the respective opposing end about a central region thereof and extends radially outwardly therefrom. Each tine includes a frame body having a central ridge and opposing lower extensions, the lower extensions terminating at an exposed face. The portion of the lower extensions proximate the exposed face being able to move relative to the rest of the frame body so as to better position on the teeth of a patient. A superimposed pad over portions of the frame body provides a deformable surface for engagement with the surface of the tooth of a patient. | 2014-08-28 |
20140242545 | ABUTMENT POSITION LOCATOR - The present application relates to a fitting for insertion into a dental implant in an insertion orientation defining a central insertion axis (X) and an insertion direction (D) of the fitting. The fitting comprises at least one resilient spring member being expandable perpendicularly to the insertion axis (X) of the fitting for impeding a movement of the fitting relative to the dental implant along the insertion axis (X) when inserted into the dental implant. It further comprises an alignment feature for rotationally aligning the fitting relative to the dental implant about the insertion axis (X). The fitting is characterized in that the alignment feature extends further in the insertion direction (D) than the spring member. | 2014-08-28 |
20140242546 | ENDOSSEOUS DENTAL IMPLANT AND ABUTMENT FOR PREVENTION OF BONE LOSS - Endosseous dental implants and abutments for deterring tissue loss, such as loss of buccal bone, at the site of the implant/abutment. An exemplary implant may include longitudinally extending externally threaded and unthreaded regions each extending over only a circumferential portion of the external circumference of the implant. The implant may include an internal passage extending along the shaft having a frusto-conical region extending over only a circumferential portion of the internal passage. An exemplary abutment may include a distal connection end comprising a frusto-conical region thereat extending over only a circumferential portion of the external circumference of the connection end to provide a frusto-conical connection region and non-frusto-conical connection region. | 2014-08-28 |
20140242547 | DENTAL BRIDGE - A system for attaching a natural tooth to a dental implant. The system comprises a dental prosthesis and an elastomeric cushion. The dental prosthesis has a first end and a second end. The first end is fixed to a natural tooth and the second end is engaged with a dental implant. The elastomeric cushion is positioned in contact, either directly or indirectly, with at least a portion of the dental implant and at least a portion of the dental prosthesis such that the elastomeric cushion permits movement of the second end relative to the dental implant in response to movement of the natural tooth transferred through the dental prosthesis to the second end. | 2014-08-28 |
20140242548 | DENTAL BRIDGE - A system for attaching a natural tooth to a dental implant. The system comprises a dental prosthesis and an elastomeric cushion. The dental prosthesis has a first end and a second end. The first end is fixed to a natural tooth and the second end is engaged with a dental implant. The elastomeric cushion is positioned in contact, either directly or indirectly, with at least a portion of the dental implant and at least a portion of the dental prosthesis such that the elastomeric cushion permits movement of the second end relative to the dental implant in response to movement of the natural tooth transferred through the dental prosthesis to the second end. | 2014-08-28 |
20140242549 | SHELL PLATE FOR ARTIFICIAL TEETH WITH ARRANGEMENT ASSISTING FUNCTION - An artificial teeth packaging container includes an artificial teeth accommodating portion for fixing a plurality of continuously arranged artificial teeth detachably, and holding an arrangement position relation with an adjacent artificial teeth and an arrangement position relation with an upper or lower artificial molar teeth, in which the artificial teeth accommodating portion covers the plurality of artificial teeth from an occlusal plane in a state exposed around a cervical portion. | 2014-08-28 |
20140242550 | DENTAL PROSTHESIS AND METHOD FOR THE PRODUCTION THEREOF - A dental prosthesis, includes a metal framework having at least one cap, which can be joined to an abutment of a dental implant. The metal framework includes a connecting element which can be, or is, joined to the cap in the oral cavity of a patient, in particular by way of welding, soldering or gluing, wherein the cap has a tip and, on the inside, a cavity into which the abutment can be inserted through an opening located opposite the tip. It is the object to refine the dental prosthesis and/or the metal framework so as to allow improved handling and/or facilitated creation of the, in particular intra-oral, preferably welded, joint with low design complexity. This object is attained by providing a pin arranged as an axial extension in the region of the tip of the cap and the connecting element is joined to the pin. | 2014-08-28 |
20140242551 | Oral Care System and Method - An oral care system and method for the treatment of certain oral pathological conditions that require the cleaning and cleansing of the underlying scaffolding of the tooth. The oral care system and method generally includes applying chlorine dioxide liquid or gel to a diseased portion of the tooth and activating it so as to clean the aforementioned. A tool is utilized to activate the chlorine dioxide liquid thereby releasing its cleaning action. Another process utilizes repetitive steps of water and chlorine dioxide activated with a tool to cleanse the inner regions of an affected tooth. | 2014-08-28 |
20140242552 | POWDER FOR DENTAL POWDER BLASTING - The present invention relates to calcium carbonate particles, a powder mixture comprising said particles and a tooth cleaning method wherein the particles or powder mixture are used. | 2014-08-28 |
20140242553 | REAL-TIME SIMULATION SYSTEM OF THE EFFECTS OF ROTOR-WAKE GENERATED AERODYNAMIC LOADS OF A HOVER-CAPABLE AIRCRAFT ON THE AIRCRAFT ITSELF, AND METHOD THEREOF - A real-time simulation system of the aerodynamic loads generated by the wake of a rotor of a hover-capable aircraft on the aircraft itself is described, said system comprising: a cockpit seat for a pilot; a simulated control device of the aircraft able to receive a simulated command from the pilot to simulate a flight condition of the aircraft; simulation means able to generate a simulated representation of the flight condition; and a processing unit configured to receive as input a first signal associated with the command given via the control device and to generate and output a second control signal for the simulation means associated with the simulated aerodynamic loads. The processing unit cyclically generates a vortex ring with a radius, associates a number of control points with the vortex ring, computes the velocity induced on the control points, moves and updates the vortex ring, and generates the second signal on the basis of the velocities induced on the control points by the vortex rings. | 2014-08-28 |
20140242554 | SYSTEM FOR ENABLING A VISUALLY IMPAIRED OR BLIND PERSON TO USE AN INPUT DEVICE HAVING AT LEAST ONE KEY - System for enabling a visually impaired or blind person to use an input device having at least one key, comprising: at least one tactile sensor array, in particular a pressure sensor array, attachable to a fingertip of a visually impaired or blind person for acquiring a pressure distribution image of a key slightly touched by a finger of said person when attached to said finger, a pressure distribution image processing and character recognition unit that is connected to said tactile sensor array for processing said pressure distribution image and for recognizing the key label of the touched key and an audio output device that is connected to said unit for outputting and acoustic reproduction of said key label. | 2014-08-28 |
20140242555 | Braille Display Device And Method Of Constructing Same - Disclosed is a Braille display device. The device supports an array of individual Braille cells with corresponding tactile pins. The pins can be selectively lifted by way of reeds to generate Braille characters that can be felt by the user. The Braille characters can correspond to visible characters, such as characters on a computer screen. The display is refreshable to allow for the sequential display of lines, paragraphs, or pages. In accordance with the disclosure, the Braille cells are constructed in a manner that minimizes manufacturing costs and that also permits the size of the display to be greatly reduced. | 2014-08-28 |
20140242556 | DIET MANAGEMENT SYSTEM AND METHOD - The present invention relates to a diet management system and method, wherein individual information data about users going through diet management are received and users are classified by body morphology, and a user-specific customised solution is provided in accordance with user body morphology classification-based diet targets, lifestyle analysis results and condition diagnostic data, and the user's current circumstances are received and a customised solution is provided that has been changed to match therewith. The present invention makes it possible to provide, in timely fashion, a solution wherein systemic diet management is effected that matches the characteristics of each individual person who is dieting, and wherein changes are effected so as to reflect the current condition of the person who is dieting. | 2014-08-28 |
20140242557 | AUDIBLE DICTIONARY DEVICE AND METHOD - An audible dictionary device defined by a device housing having a multipart screen display, an lock button, a command button, a headphone jack, a keyboard, a speaker, and a detachable stylus. Internally, the audible dictionary device includes a power source, a processor, non-volatile memory, an internal database of reference information. In some embodiments, a network interface which enables the audible dictionary device to receive reference information from a network location is included in addition to or in the alternative of the internal database. The device executes a process by which words are looked up by a user, with the user then being provided with various reference information and be provided audibly in addition to on screen about the looked up word. | 2014-08-28 |
20140242558 | Bartender Training Method and Apparatus - A bartender training method and apparatus is provided, wherein the same can be deployed as a training course adapted to train users the art of mixology and efficient bartending skills. In an exemplary embodiment, the present invention contemplates one or more bar stations set up for making and serving mixed drinks, wherein each bar station comprises an interactive display screen and a slop bin to receive prepared drinks. The interactive display screen prompts each user with drink orders of varying complexity, whereby drink details may be provided for beginning learners and more difficult commands and routines are requested as experience is gained. Upon course completion, user performance data is used for grading purposes and for providing the user with a profile to show would-be employers. The present invention improves current methods of bartending training and emphasizes speed and efficiency of drinking making. | 2014-08-28 |
20140242559 | METHOD AND SYSTEM FOR EEG-BASED TASK MANAGEMENT - A method and system are disclosed for determining a task for a subject, which includes sensing electrical activity along a scalp of a subject; characterizing a mental state of the subject based on the electrical activity of the subject; comparing the mental state of the subject with a pre-defined task list to select a task for the subject based on the mental state of the subject; and assigning the task to the subject based on the comparison of the mental state of the subject and the pre-defined task list. | 2014-08-28 |
20140242560 | FACIAL EXPRESSION TRAINING USING FEEDBACK FROM AUTOMATIC FACIAL EXPRESSION RECOGNITION - A machine learning classifier is trained to compute a quality measure of a facial expression with respect to a predetermined emotion, affective state, or situation. The expression may be of a person or an animated character. The quality measure may be provided to a person. The quality measure may also used to tune the appearance parameters of the animated character, including texture parameters. People may be trained to improve their expressiveness based on the feedback of the quality measure provided by the machine learning classifier, for example, to improve the quality of customer interactions, and to mitigate the symptoms of various affective and neurological disorders. The classifier may be built into a variety of mobile devices, including wearable devices such as Google Glass and smart watches. | 2014-08-28 |
20140242561 | METHOD OF TREATING SPINAL PROBLEMS IN HUMANS - A medical non-invasive treatment of humans for treating spinal disorders, such as spinal curvature, osteochondrosis, scoliosis, and other related problems. The treatment includes formation of stable synaptic connections in the patient's mind by means of forming patient's conditional reflexes to the ideal way of performing an exercise, as shown by the expert. The treatment leads to formation of correct posture through the process comprising: patient being treated while standing, sitting or lying; a special film running on the screen, which shows an expert, who ideally performs exercises, and accentuates attention on certain parts of the spine by highlighting them and playing sounds of varying volume; the same parts of the patient's spine are being touched by the coach, a partner or the patient themselves simultaneously with the video. | 2014-08-28 |
20140242562 | ELECTRONIC HAND WASHING REMINDER - A motion detection device that offers an audio/video reminder to wash the hands is disclosed. The device is desirable for use in public restrooms or other environments where frequent hand washing is required. The device provides a product that can effectively increase hygienic hand washing while educating patrons of proper hand washing techniques and optionally the health benefits and/or health code requirements of doing so. | 2014-08-28 |
20140242563 | DRUG, SURGICAL, AND MEDICAL EDUCATION PROCESSES - A national standardized protocol developed by interfacing the FDA, medical societies, pharmaceutical companies, surgical companies, and patient focus groups for education patients about medications and surgical procedures which can be modified as new risks are discovered is desirable. Linking patient metadata to received information and then being able to identify patients about new risks and communicate to each patient is also desirable. Patients should receive all currently available information about a medication or surgical procedure and receive any newly discovered information. | 2014-08-28 |
20140242564 | PORTABLE LAPAROSCOPIC TRAINER - A portable surgical training device is provided. The trainer includes a top cover spaced apart from a base to form a simulated body cavity for locating model organs that are substantially obscured from the field of view of the user. The top cover includes a video display, fixed insertion ports and interchangeable inserts containing simulated tissue layers. The training device has open sides for demonstrating and training lateral surgical techniques including a simulated or live tissue colon attached to a support leg for simulating transanal minimally invasive surgery. A training endoscope with an adjustable focal length for use with the trainer and, in particular, with optical trocars is disclosed. The surgical trainer can be angled and is well suited for training laparoscopic surgery techniques and demonstrating surgical instruments. | 2014-08-28 |
20140242565 | QUALITY MANAGEMENT SYSTEM AND PROBLEM SOLVING LEARNING ENVIRONMENTS AND DESIGN FOR 21st CENTURY SKILLS - A system for managing course content for a course includes a database configured to store course content. Course content includes problem-solving learning environments and design (PSLED) blocks. An interface is configured to provide information from a PSLED block for a student. An input and output module are configured to receive and send input regarding at least one of the PSLED blocks stored in the database. An evaluation module is configured to evaluate the student based on assessment requirements in at least one of the PSLED blocks stored in the database and based on the assessment data. A mapping module is configured for analyzing and mapping attributes between PSLED blocks stored in the database, the attributes including at least one of equivalency of instructional units, equivalency of standards of learning and practice, equivalency of micro-certificates, and equivalency of micro-credentials. | 2014-08-28 |
20140242566 | TECHNIQUES FOR USE IN COMMUNICATIONS OF SYSTEMS FOR TARGETED DATACASTING - A central server outside of a school network receives assignments from educator computing devices, where each assignment includes content for distribution to student computing devices and a schedule indicating when the assignment is active for distribution. A local server within the school network receives the assignments and stores the assignments in a local server datastore. The local server receives from a gateway within the school network a request for active assignments, identifies the active assignments, and returns a list of the active assignments to the gateway. The gateway determines whether the list of the active assignments contains any assignments unretrieved by the given gateway. If so, the gateway sends to the local server a request for the unretrieved assignments. The gateway receives the requested assignments from the local server and stores them in a gateway datastore. | 2014-08-28 |
20140242567 | Underlying Student Test Error Detection System and Method - A system for improving a student's knowledge or problem solving skills that identifies errors of a student's understanding of an underlying topic or application of a requisite skill needed to answer a test question correctly. The system includes a computer with a testing software program that presents a set of two or more questions regarding a topic to a student. Associated to the topic is a set of core concepts. Each question is associated with one or more core concepts and related with the other questions so that at least one core concept matches the core concept on the other questions. When the student incorrectly answers a question, the core concepts associated with the question is reviewed and the answers to the questions containing the matching core concepts are reviewed. If a question associated with the common core concept is previously answered correctly, the core concept associated exclusively to the question answered incorrectly is deemed the source of the error. Instructional materials associated with the core concept deemed to the source of the error are provided to the student. | 2014-08-28 |
20140242568 | APPARATUS FOR REPRODUCING AND ERASING MAGNETIC VISUAL INFORMATION - The invention relates to an apparatus for temporarily displaying visual information, comprising a frame, a plate of material included in the frame that changes colour due to local pressure and when exposed to a magnetic field, assumes its original colour, a magnet movable along the plate, guide means for guiding the magnet along the sheet in a fast position, wherein the magnet is arranged for erasing a part of the plate by its magnetic field during the movement along the plate, whereby the guide means arc arranged for guiding the magnet along a path in a second position different from the first position, whereby the magnetic field generated by the magnet does not erase the first part of the plate and the device comprises operation means for operating between the first and second position of the magnet. | 2014-08-28 |
20140242569 | Poultry Performance - Methods for increasing breast muscle weight in poultry are disclosed herein. These methods can include delivery of compositions via in ovo administration. The methods disclosed herein also encompass the delivery of proteins. The methods disclosed herein are effective for increasing breast muscle weight in poultry, both in the embryo, and at slaughter age. | 2014-08-28 |
20140242570 | METHOD FOR PICKING UP CELL MATERIAL AND ASSEMBLY FOR PERFORMING SAID METHOD - In a method for picking up cell material from a culture dish a picking tool is displaced towards the cell material. Contact between the tool and the cell material is determined by carrying out capacitive measurements. After contact the tool is removed from the cell material. In an assembly for performing said method a support made of electrically conducting material supports the dish. A measurement device determines the start electrical capacity of the system composed of picking tool and support in a starting position of the tool, and determines the electrical capacity of the system when lowering the tool towards the dish. The measurement device provides signals representing the electrical capacity to a controller, which comprises a comparator for performing a comparison of the electrical capacity during lowering of the tool with the start electrical capacity. The controller controls the positioning of the tool at least based on this comparison. | 2014-08-28 |
20140242571 | OPTICAL ELEMENT, ANALYSIS EQUIPMENT, ANALYSIS METHOD AND ELECTRONIC APPARATUS - An optical element includes a metal layer in which a first direction is a thickness direction; metallic particles provided to be spaced from the metal layer in the first direction; and a light transmitting layer that separates the metal layer from the metallic particles, in which the size T of the metallic particles in the first direction satisfies a relationship of 3 nm≦T≦14 nm, and the size D of the metallic particles in a second direction orthogonal to the first direction satisfies a relationship of 30 nm≦D<50 nm. | 2014-08-28 |
20140242572 | CHROMATOGRAPHY METHOD, CHROMATOGRAPHY KIT, AND METHOD OF PRODUCING AN INSOLUBLE CARRIER FOR CHROMATOGRAPHY - A chromatography method including a step of developing a complex of a specimen and a labeled substance modified by a first bondable substance which can be bonded to the specimen on an insoluble carrier, a step of capturing the complex of the specimen and the labeled substance at a reactive site on the insoluble carrier, a step of washing the reactive site on the insoluble carrier using a washing liquid, a step of detecting the specimen which is captured at the reactive site after a signal of the labeled substance is amplified by an amplification liquid, in which the reactive site on the insoluble carrier includes (i) a second bondable substance which can be bonded to the specimen or a substance having affinity to the first bondable substance which can be bonded to the specimen, and (ii) polyethylene glycol having the molecular weight from 1,500 to 10,000. | 2014-08-28 |
20140242573 | OPTICAL ELEMENT, ANALYSIS DEVICE, ANALYSIS METHOD AND ELECTRONIC APPARATUS - An optical element includes a metal layer having a thickness in a first direction; metallic particles spaced apart from the metal layer in the first direction; and a light transmitting layer separating the metal layer from the metallic particles. The metallic particles are disposed in a lattice shape in a second direction orthogonal to the first direction and in a third direction orthogonal to the first direction and the second direction. A distance between adjacent metal particles in the second and third directions is S, and 6 nm2014-08-28 | |
20140242574 | CODON-OPTIMIZED GENE FOR MUTATED SHRIMP LUCIFERASE AND METHOD FOR USE THEREOF - There has been a demand for a codon-optimized gene for the mutated catalytic domain of | 2014-08-28 |
20140242575 | KITS AND METHODS FOR IN VITRO ANALYTE DETECTION USING PRECIPITATING COMPOUND AND POLARIZERS - The invention provides inexpensive kits and methods for determination of an analyte in a sample with very high sensitivity. Analyte can be determined using an analyte binding member such as an antibody or an oligonucleotide, which can be directly or indirectly linked to an enzyme. The kit and method uses a compound that is altered in the presence of the enzyme, and that precipitates into crystalline particulates. The reaction composition with crystalline particulates is placed between two polarizers which are in an orthogonal arrangement, and the presence of particulates is observed, correlating to the analyte in the sample. | 2014-08-28 |
20140242576 | METHODS FOR DETERMINING NUCLEOTIDE SEQUENCE REPEATS - The invention relates to methods to reduce the length of a homonucleotide repeat sequence a target DNA sequence. This is done by using an oligonucleotide primer which extends in the unaltered repeat of identical nucleotides of the target polynucleotide, the oligonucleotide primer comprises at the at the 5′ side a sequence which hybridizes with the sequence preceding the targeted sequence repeat, but the oligonucleotide primer is not 100% complementary with the sequence repeat in the target sequence. | 2014-08-28 |
20140242577 | C-PROBE LIBRARIES FOR DNA TARGET ENRICHMENT - Provided herein is a method for enriching a target nucleic acid molecule. In one embodiment, the method may involve hybridizing a C-probe to a strand of a target nucleic acid to produce a complex, enzymatically removing any 3′ overhanging end from the target nucleic acid of the complex to produce a 3′ hydroxyl group at the 3′ end; extending the 3′ end of the first sequence using the oligonucleotide sequence of the C-probe as a template; enzymatically removing any 5′ overhanging end from the target nucleic acid, either before or after the extending step, to produce an 5′ phosphate group at the end of the second sequence; and ligating the 5′ phosphate group at the end of the second sequence to the 3′ hydroxyl group at the end of the first sequence to produce a circular DNA molecule that contains the target sequence and the complement of the oligonucleotide sequence. | 2014-08-28 |
20140242578 | SIMULTANEOUS DETECTION OF MULTIPLE MIRNAS USING CAPILLARY ELECTROPHORESIS SYSTEM EQUIPPED WITH PLURAL LASER-INDUCED FLUORESCENCE DETECTORS - The present invention relates to a method for simultaneously detecting multiple miRNAs present in a sample and a kit for detecting same. According to the present invention, two or more miRNAs existing in trace amounts in a sample can be analyzed through only one measurement. The detection method of the present invention may be used for fast diagnosis of various diseases wherein miRNAs are involved, for example, cardiovascular diseases including myocardial infarction, with high accuracy. | 2014-08-28 |
20140242579 | REVERSIBLE TERMINATOR MOLECULES AND METHODS OF THEIR USE - The present invention relates generally to methods of sequencing of polynucleotides and compounds, compositions and kits useful for sequencing of polynucleotides. The chemical compounds include nucleotide and nucleoside analogs which possess a blocking group covalently attached to the 3′ hydroxyl of the sugar moiety. The blocking group may optionally be additionally covalently attached to a linker and/or detectable label. The nucleotide analogs may be ribonucleotide or deoxyribonucleotide analogs. Methods include incorporation of the reversible terminator molecules into growing polynucleotide strands by polymerase enzymes, such as in single base sequencing methodologies utilizing sequential reversible termination techniques. | 2014-08-28 |
20140242580 | METHOD FOR PREDICTING RESPONSE OR PROGNOSIS OF LUNG ADENOCARCINOMA WITH EGFR-ACTIVATING MUTATIONS - The invention provides a method for predicting the response of an EGFR-activating mutant subject suffering from a lung adenocarcinoma and receiving treatment with epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) and a method for predicting prognosis in an EGFR-activating mutant subject suffering from a lung adenocarcinoma and receiving treatment with EGFR-TKI. In the methods of the invention, clustered genomic alterations in specific chromosomes (in particular chromosomes 5p, 7p, 8q or 14q) are determined as a tool for predicting the response or prognosis. | 2014-08-28 |
20140242581 | COMPOSITIONS AND METHODS FOR GENETIC ANALYSIS OF EMBRYOS - The present disclosure provides for compositions and methods for genetic analysis of embryos. Generally, the compositions and methods provide for the acquisition of an sample containing RNA from an embryo, genetic analysis involving various techniques such as sequencing-, hybridization- or amplification-based methods, and the detection of genetic alterations that may affect the health and quality of the embryo. In some cases, compositions and methods of this disclosure may provide information useful in the selection and monitoring of embryos for implantation into a female. | 2014-08-28 |
20140242582 | DETECTION OF GENETIC ABNORMALITIES USING LIGATION-BASED DETECTION AND DIGITAL PCR - The present invention provides assays systems and methods for detection of genetic variants in a sample, including copy number variation and single nucleotide polymorphisms. The invention preferably employs the technique of tandem ligation, i.e. the ligation of two or more fixed sequence oligonucleotides and one or more bridging oligonucleotides complementary to a region between the fixed sequence oligonucleotides combined with digital PCR detection. | 2014-08-28 |
20140242583 | ASSAYS, METHODS AND COMPOSITIONS FOR DIAGNOSING CANCER - The present invention provides a method and single-tube assay for identification and quantitative analysis of differentially methylated MLH1 promoter sequences that are associated with certain types of cancer in an individual by obtaining a biological sample comprising DNA from the individual, detecting the presence of and measuring the level of methylated MLH1 promoter sequences, and comparing the presence of and level of methylation in the sample to a normalization reference of “normal” beta-actin gene promoters, wherein a difference in the level or pattern of MLH1 methylation of the sample compared to the Actin gene reference level identifies abnormally methylated MLH1 promoter sequences associated with cancer. | 2014-08-28 |
20140242584 | GENOMIC DNA EXTRACTION REAGENT AND METHOD - The present invention is directed to a genomic DNA extraction reagent and method for improved extraction of DNA from biological tissue. The extraction reagent of the invention is mixed with disrupted biological tissue to form a DNA extraction solute which is incubated in a DNA extraction step. The extraction reagent includes an alkali component to maintain the DNA extraction solute at a pH of about 10 to 14 substantially throughout the extraction step. The extraction solute is centrifuged to clarify the supernatant. The supernatant containing the extracted DNA is diluted with a neutralizing buffer resulting in a high throughout method of generating high quantities of high quality DNA. Major PCR inhibitors are managed with the unique chemical combinations of the DNA extraction reagent designed and optimized for extraction of DNA from plant tissue and cells. | 2014-08-28 |
20140242585 | Genetic Test for the Identification of Carriers of Complex Vertebral Malformations in Cattle - Genetic markers for identifying bovine carriers of complex vertebral malformation (CVM) disease gene are described. The genetic markers, including the microsatellite markers BM4129, INRAA003, BMS2790, ILSTS029, INRA123, BM220, HUJ246, BMS862, BMS937, BL1048, BMS2095 and BMS1266 and the bovine SLC35A3 gene, are located on bovine chromosome BTA3. The G/T polymorphism at position 559 of the bovine SLC35A3 gene is identified as being causative and diagnostic for CVM in cattle. | 2014-08-28 |
20140242586 | CHIMERIC PRIMERS WITH HAIRPIN CONFORMATIONS AND METHODS OF USING SAME - Methods and compositions for nucleic acid amplification, detection, and genotyping techniques are disclosed. In one embodiment, a nucleic acid molecule having a target-specific primer sequence; an anti-tag sequence 5′ of the target-specific primer sequence; a tag sequence 5′ of the anti-tag sequence; and a blocker between the anti-tag sequence and the tag sequence is disclosed. Compositions containing such a nucleic acid molecule and methods of using such a nucleic acid molecule are also disclosed. | 2014-08-28 |
20140242587 | Rapid and Reliable Detection of Infectious Agents - The present invention is directed to devices, systems and methods that enable the detection of low copy numbers of bacterial polynucleotides in a sample without having to use multiple species specific primer sequences. | 2014-08-28 |
20140242588 | METHODS AND PROCESSES FOR NON-INVASIVE ASSESSMENT OF GENETIC VARIATIONS - Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations. | 2014-08-28 |
20140242589 | HYBRIDIZATION COMPOSITIONS AND METHODS - The invention provides methods and compositions for hybridizing at least one molecule to a target. The invention may, for example, utilize a of cyclic and/or non-cyclic solvent that is non-toxic and may eliminate or reduce the amount of formamide in the hybridization composition. | 2014-08-28 |
20140242590 | FLT3 MUTATIONS ASSOCIATED WITH DRUG RESISTANCE IN AML PATIENTS HAVING ACTIVATING MUTATIONS IN FLT3 - The invention provides methods and compositions for identifying acute myeloid leukemia (AML) patients that have an increased likelihood of a relapse following treatment with AC 220. | 2014-08-28 |
20140242591 | METHOD OF DIAGNOSING AND PREVENTING PNEUMOCOCCAL DISEASES USING PNEUMOCOCCAL NEURAMINIDASES - A method of providing protection against pneumococcal infection in a subject is disclosed. The method includes steps of administering to the subject a composition that includes combination of three recombinant pneumococcal neuraminidases: NanA, NanB, and NanC of | 2014-08-28 |
20140242592 | Allele-Specific Amplification - The present invention includes a method of allele-specific amplification, utilizing an allele-specific oligonucleotide, at least partially complementary to more than one variant of the target sequence, but having a 3′-terminal nucleotide complementary to only one variant of the target sequence and having at least one nucleotide with a base covalently modified at the exocyclic amino group, wherein the allele-specific oligonucleotide is extended by a nucleotide-incorporating biocatalyst predominantly when hybridized to the variant of the target sequence for which it has said complementary 3′-terminal nucleotide. | 2014-08-28 |
20140242593 | Sample Chamber Array and Method for Processing a Biological Sample - A sample chamber array is provided. The sample chamber array may comprise at least one reservoir in fluid communication with at least one sample chamber, and a movable portion defining the sample chamber. The reservoir is fillable with a liquid biological sample. The movable portion may be movable with respect to the remainder of the sample chamber from a first position to a second position. In the first position the movable portion is concave and the sample chamber is without biological sample. In the second position the movable portion is convex and the sample chamber comprises biological sample. The movement of the movable portion to the second position causes a pressure drop to transport the biological sample into the sample chamber from the at least one reservoir. Methods for processing a biological sample and methods of making a sample chamber array are also provided. | 2014-08-28 |
20140242594 | METHODS AND COMPOSITIONS FOR PREPARATION OF NUCLEIC ACIDS - A method for isolating genomic DNA (gDNA) from a biological material. In some embodiments, the method includes (a) contacting a sample that contains gDNA with a solution of hydroxide and a detergent under conditions and for a time sufficient to degrade a cell wall, a cell membrane, a nuclear membrane, a nucleoprotein, or combinations thereof and/or to denature the gDNA; (b) mixing into the solution resulting from step (a) a solution characterized by high salt and sufficient buffering capacity to reduce the pH of the solution to less than 10, thereby producing a neutralized solution; (c) centrifuging the sample at a speed and length of time sufficient to clarify the preparation; and (d) removing insoluble material from the neutralized and clarified preparation, whereby a solution of gDNA is produced. Also provided are method for performing a quantitative polymerase chain reaction (qPCR) of a gDNA sample, methods for performing genotyping or other molecular marker analysis of a gDNA sample, and methods for determining a haplotype of a cell. | 2014-08-28 |
20140242595 | HEPATOCYTE PRODUCTION VIA FORWARD PROGRAMMING BY COMBINED GENETIC AND CHEMICAL ENGINEERING - The present invention provides methods comprising both genetic and chemical means for the production of hepatocytes from a variety of cell sources, particularly pluripotent stem cells. | 2014-08-28 |
20140242596 | Systems and Methods for Biological Analysis - A case for containing a plurality of biological samples contains a base, a substrate and a cover. The substrate is attached to the base and comprises a plurality of reaction regions configured to receive one or more biological samples. The cover comprises an inner surface and is configured to be attached to the base such that the base and cover together provide a cavity containing the substrate. The inner surface includes a central area and a recessed area disposed about the central area. The central area is configured to cover the reaction regions, while the recessed area is offset from the central area in a direction normal to the inner surface. | 2014-08-28 |
20140242597 | PREDICTING TUMOR RESPONSE TO ANTI-ERBB3 ANTIBODIES - A diagnostic method for predicting quantitatively whether a human tumor will be sensitive or resistant to treatment with an ERBB3 inhibitor, e.g, an anti-ERBB3 antibody, is disclosed. The method is based on measurement of NRG1 expression at the RNA level, or at the protein level, in a tissue sample from the tumor. | 2014-08-28 |
20140242598 | MULTIPLEX PCR-BASED TESTING OF CUTANEOUS SQUAMOUS CELL CARCINOMA AND PSEUDOEPITHELIOMATOUS HYPERPLASIA AND METHODS FOR DISTINGUISHING THE SAME - Methods for differentiating squamous cell carcinoma from pseudoepitheliomatous hyperplasia in a biological sample using KRT9 and C15orf48, methods of using differentially expressed genes as prognostic markers for squamous cell carcinoma, methods of using molecular pathways as targets for the treatment of squamous cell carcinoma, and diagnostic kits therefor. | 2014-08-28 |