34th week of 2009 patent applcation highlights part 39 |
Patent application number | Title | Published |
20090208899 | Fluid bypass device for handheld dental devices - A bypass device and kit for delivering a fluid to a dental area for use with a dental handpiece. The device comprises a fluid reservoir, a length of hollow tubing that will be attached externally to the handpiece, and a nosepiece connected to the tubing. Fluid is delivered to the dental area through the nosepiece, independently of the dental handpiece. | 2009-08-20 |
20090208900 | Bifunctional dental apparatus - The invention teaches an apparatus used in dental care service for providing gaseous oxygen to a patient and removing dental impurities from the patient's mouth concurrently. The apparatus includes a first bendable nozzle for dispensing gaseous oxygen to a space near the patient's nose and a second bendable nozzle for sucking dental impurities from the patient's mouth. | 2009-08-20 |
20090208901 | Dental implement for tooth restoration - A dental implement comprising a biasing ring and a pair of opposing tines. The biasing ring includes a substantially hoop-like configuration terminating at two opposing ends which are spaced apart from each other a distance. The pair of opposing tines extend inwardly from each of the two ends of the biasing ring toward each other. Each of the pair of opposing tines is coupled to the respective opposing end about a central region thereof and extends radially outwardly therefrom. Each tine includes a front face having opposing sides, a top end and a bottom end. The front face is defined by two inwardly inclined surfaces which start at the opposing sides and incline inwardly toward each other and intersect to form a peak that extends at least partially between the top end and the bottom end of the front face. The peaks of the opposing tine assemblies face each other. | 2009-08-20 |
20090208902 | DENTAL DRILL MADE OF PLASTICS - The invention refers to a dental drill comprising a head provided with cutting edges, which has an at least rounded basic shape, wherein two of the cutting edges at the front side merge into a transitional cutting edge, characterized in that the dental drill is made of a plastics material which has a hardness between 60 and 250 Knoop. | 2009-08-20 |
20090208903 | METHOD FOR MANUFACTURING DISPOSABLE ROTARY CUTTING TOOLS AND DISPOSABLE ROTARY TOOL FOR DENTAL OR MEDICAL APPLICATIONS - The shank ( | 2009-08-20 |
20090208904 | Dental implant - A dental implant is described, which has an internal axial force absorbing the dissipating member encased within resilient material so as to suspend a prosthetic supporting section. | 2009-08-20 |
20090208905 | EXPANDABLE DENTAL IMPLANTS OF HIGH SURFACE AREA AND METHODS OF EXPANDING THE SAME - A dental implant system for placement within a jaw of a patient includes an envelope including an outer surface and an inner surface defining a barrel. At least one barrier is located in the barrel. The barrel having a first region on one side of the barrier and a second region on an opposing side of the barrier. An expander member is movable within the barrel along a longitudinal axis of the barrel from the first region to the second region. The barrier prohibits the expander member from moving from the second region to the first region. | 2009-08-20 |
20090208906 | DENTAL IMPLANT - A dental prosthesis comprises an implant, an abutment and a crown. The implant has distal and proximal portions with the implant proximal portion including distal and proximal segments. The implant proximal segment has an outer surface. The abutment has distal and proximal segments and defines an abutment shoulder therebetween. The abutment shoulder is configured to circumferentially engage the outer surface of the implant proximal segment such that an implant abutment joint is defined therebetween. The crown is configured to be positioned over the abutment and the implant such that the crown covers the implant abutment joint. The implant proximal segment has an annular concave cross-section such that the crown distal end has a rounded shape to reduce the potential for stress cracking of the crown. | 2009-08-20 |
20090208907 | DENTAL IMPLANT - The invention relates to dentistry, in particular to a group of dental implants used for two-stage implantation into the alveolar bone. Said invention makes it possible to create the conditions for successful ingrowth of bone and soft tissues into the implant obtainable by the best ingrowth of the bone tissue into the internal porous structure and the soft tissue ingrowth into a surface porous three-dimensional structure in the area of the alveolar bone. The inventive cylindrical implant, the base of which is made of titanium, comprises a cavity for the porous structure and a channel for injecting medicinal preparations, wherein the base is embodied in the form of an external thread-shaped spiral which is fastened to three longitudinal reinforcing ribs arranged inside the spiral together with the porous structure, the pore size of which ranges from 150 to 300 mkm. | 2009-08-20 |
20090208908 | Notched pontic and system for fabricating dental appliance for use therewith | 2009-08-20 |
20090208909 | DENTAL FILLERS AND COMPOSITIONS INCLUDING PHOSPHATE SALTS - The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes a phosphate salt. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment. Dental compositions, and methods of using dental compositions that include a phosphate salt and a hardenable resin or a water-dispersible, polymeric film former are also provided. | 2009-08-20 |
20090208910 | AUTOMATED EXECUTION AND EVALUATION OF NETWORK-BASED TRAINING EXERCISES - This disclosure generally relates to automated execution and evaluation of computer network training exercises, such as in a virtual machine environment. An example environment includes a control and monitoring system, an attack system, and a target system. The control and monitoring system initiates a training scenario to cause the attack system to engage in an attack against the target system. The target system then performs an action in response to the attack. Monitor information associated with the attack against the target system is collected by continuously monitoring the training scenario. The attack system is then capable of sending dynamic response data to the target system, wherein the dynamic response data is generated according to the collected monitor information to adapt the training scenario to the action performed by the target system. The control and monitoring system then generates an automated evaluation based upon the collected monitor information. | 2009-08-20 |
20090208911 | FLIGHT SIMULATOR YOKE - A flight simulator yoke is provided having a single handle having a handgrip and yoke shaft operable from a left side of a user, wherein a neutral position for the handle is at a 45 degree angle. The yoke may further include two trim axes traverse to each other; and two moveable spring devices. The spring devices are operatively coupled to the trim axes, each spring device having a positive center detent, wherein the positive center detent requires a predetermined amount of force in order to move the yoke along each trim axis. The flight simulator yoke may simulate a yoke of a Cirrus aircraft. | 2009-08-20 |
20090208912 | Process that produces two-dimensional symbols from words - A process that occurs within a border made up of the twenty-six-letter English alphabet that produces two-dimensional symbols from words by creating one continuous line from the first letter of a word being processed to the next letter of the same word being processed. This process continues in one unbroken line until the last letter of the word being processed has been reached. Once the last letter of the word being processed has been reached, the process stops. | 2009-08-20 |
20090208913 | SYSTEM AND METHOD FOR EXPRESSIVE LANGUAGE, DEVELOPMENTAL DISORDER, AND EMOTION ASSESSMENT - In one embodiment, a method for detecting autism in a natural language environment using a microphone, sound recorder, and a computer programmed with software for the specialized purpose of processing recordings captured by the microphone and sound recorder combination, the computer programmed to execute the method, includes segmenting an audio signal captured by the microphone and sound recorder combination using the computer programmed for the specialized purpose into a plurality recording segments. The method further includes determining which of the plurality of recording segments correspond to a key child. The method further includes determining which of the plurality of recording segments that correspond to the key child are classified as key child recordings. Additionally, the method includes extracting phone-based features of the key child recordings; comparing the phone-based features of the key child recordings to known phone-based features for children; and determining a likelihood of autism based on the comparing. | 2009-08-20 |
20090208914 | Door Breach Training System - A door breach training system comprising a first restraint assembly connecting a door to a frame. The door is attached to a lock jamb of the frame with a first restraint assembly that exposes a shear joint to impact from a projectile, such as shotgun round. Another embodiment further comprises attachment of the door to the hinge jamb with at least one second restraint assembly that functionally simulates a typical door hinge and exposes a shear joint to impact from a ballistic round. The preferred embodiment includes replaceable lock panels and hinge panels that are designed to break in a known manner in order to replicate those same failure modes for both door locks and door hinges in typical residential and commercial construction environments. | 2009-08-20 |
20090208915 | CLINICAL ASSESSMENT AND TRAINING SYSTEM - A system for medical training includes an anatomical simulator modeled after at least a portion of a body, the simulator including at least one external surface, and at least one cavity in fluidic communication with the external surface via a cavity. The system further includes at least one internal sensor positioned at an internal location of the anatomical simulator, the internal sensor positioned to receive an internal input based on forces applied from within the cavity, at least one external sensor positioned at an external location of the anatomical simulator and to receive an external input based on forces applied to the external surface, and a feedback display system in communication with the sensors to simultaneously record external sensor readings from the at least one external sensor and internal sensor readings from the at least one internal sensor and at least one time measurement device. | 2009-08-20 |
20090208916 | System for delivering an educational program to a remote site and for monitoring participation therein - A system for delivering an educational program to a participant at a remote site and for monitoring participation therein. The system includes a server computer, a client computer and prompting means to monitor participation by the participant. The server computer has educational program software and interacts with the client computer in order to make an educational presentation to the participant. If the participant does not adequately respond, the prompting means terminate the educational program. | 2009-08-20 |
20090208917 | DEVELOPMENTAL SYSTEM FOR TEACHING CHILDREN HEALTHY MIND, BODY AND SOCIAL HABITS - An apparatus and method for planning and tracking meals and activities comprising a display panel having a first and second side, a plurality of manipulatives for releasable attachment to the first and second sides, and an attachment device for releasably securing the display panel to a surface. A portion of the first side of the display panel bears indicia defining a category of food and a drink item. A portion of the second side of the display panel bears indicia defining an activity. The manipulatives bear indicia defining a food item, a drink item, and a serving size. In one embodiment the manipulatives and the indicia on the first and second sides of the display panel are color coordinated such that an individual may plan and track meals and activities. | 2009-08-20 |
20090208918 | METHODS AND DEVICES FOR EX-VIVO MAINTENANCE OF BONE MARROW, HEMATOPOIESIS AND BLOOD CELL PRODUCTION - Devices and methods are provided for the ex vivo maintenance of bone marrow ‘niches’ or normal physiologic home of bone marrow (BM). Intact bone marrow is perfused with a medium that supports cell viability. Stem and progenitor cells may be maintained, expanded or differentiated within the system, screened for responses to various agents, or used to generate blood products. | 2009-08-20 |
20090208919 | PARTICLE MATRIX FOR STORAGE OF BIOMOLECULES - Matrices for manipulation of biopolymers, including the separation, purification, immobilization and archival storage of biopolymers is disclosed. | 2009-08-20 |
20090208920 | ASSAY DEVICE AND METHOD - There is provided an assay device comprising a lid and a base, said base comprising, a sample addition zone, a reaction zone and an absorbing zone, said components being in fluid connection and being part of a fluid passage leading from the sample addition zone to the absorbing zone, wherein: (a) a sample addition well is integrated in the lid, (b) the absorbing zone consists of an area on an non-porous substrate, having substantially perpendicular projections, said projections defining a volume, which together with the volume of the fluid passage defines the sample volume subjected to the assay, and (c) at least one filter is between the sample addition well and the sample addition zone. There is further provided methods for handling samples. | 2009-08-20 |
20090208921 | METHODS OF DETECTION OF CANCER USING PEPTIDE PROFILES - The disclosed methods address the identification and monitoring of cancer in a subject using serum peptide profiles. Such profiles allow the detection of the differential presence of certain serum peptide markers in comparison with controls. The profiles can be determined employing mass spectrometry. | 2009-08-20 |
20090208922 | FET BASED SENSOR FOR DETECTING BIOMOLECULE, METHOD FOR PREPARING THE SAME, AND METHOD FOR DETECTING BIOMOLECULE USING THE FET BASED SENSOR - Provided is a SWNT-FET-based sensor for detection of biomolecules including an increased Schottky contact area, a method for preparing the same, and a method for detection of biomolecules using the SWNT-FET-based sensor. According to the method of the present invention, a SWNT-FET-based sensor for detection of biomolecules having a thin and increased Schottky contact area can be obtained. The biomolecule detection sensor exhibits a superior detection sensitivity, and can effectively detect both nonspecific adsorption of biomolecules and specific biomolecule-biomolecule interactions, even at a low concentration of 1 pM, for example. | 2009-08-20 |
20090208923 | System and method for diagnosing diseases - One aspect of the invention provides a method of diagnosing a disease condition, comprising measuring presence or amount of a targeted protein or a degradation product of said protein in a collected biological sample as a marker for the disease condition. The targeted protein or degradation product is selected for measurement based on a prior identification of a measurable half-life at a predetermined time period, including the time at which said method is conducted, and correlating said measuring with the presence or absence of the disease condition. The targeted protein or degradation product may be identified by selecting a protein known or suspected to be a diagnostic marker for the disease condition, analyzing degradation of the protein in the collected biological sample, and selecting a protein or degradation product that exhibits a measurable half-life at a predetermined period of time. The analyzing may include identifying degradation product(s) of the protein as a function of time, and half-life of the protein and the degradation product(s). | 2009-08-20 |
20090208924 | Generation of Replication Competent Viruses for Therapeutic Use - The present invention relates to the generation or replication-competent viruses having therapeutic utility. The replication-competent viruses of the invention can express proteins useful in the treatment of disease. | 2009-08-20 |
20090208925 | Methods and Compositions for Determining Hypersusceptibility of HIV-1 to Non-Nucleoside Reverse Transcriptase Inhibitors - This invention relates to methods for determining hypersusceptibility of HIV-1 viruses to non-nucleoside reverse transcriptase inhibitors (NNRTIs) based on the viral genotypes. The methods generally comprise detecting, in a gene encoding reverse transcriptase of the HIV-1, the presence of a mutation at codon 65, 69, or 74 alone or in combination with one or more mutations at certain other codons. Combinations of mutation associated with hypersusceptibility to NNRTIs are also disclosed. | 2009-08-20 |
20090208926 | DIAGNOSIS OF LIVER PATHOLOGY THROUGH ASSESSMENT OF PROTEIN GLYCOSYLATION - Methods for diagnosing pathology of the liver in a subject suspected of having such pathology are disclosed. The methods comprise quantifiably detecting glycosylation, and more specifically fucosylation, on proteins in biological fluids, and comparing the detected glycosylation with reference values for the glycosylation of such proteins in healthy or disease states. | 2009-08-20 |
20090208927 | Methods of detecting sequence-specific DNA binding proteins - Compositions and methods are provided for detecting and measuring DNA-binding proteins. The compositions and methods permit the simultaneous or near-simultaneous detection of multiple DNA-binding proteins in a multiplex or array format, and can be used to generate profiles of DNA binding activity by proteins, specifically, transcription factors. Multiple protein-DNA binding events in a single sample may be detected and quantitated in a high-throughput, format. | 2009-08-20 |
20090208928 | Method and device for the in vitro detection of polycystic ovarian syndrome (pcos) and pathologies involving cardiovascular risk - The invention relates to a method and device for the in vitro detection of polycystic ovary syndrome (PCOS) and pathologies involving cardiovascular risk. An in vitro assay method and assay device (kit) for the diagnosis of the presence or the predisposition to suffer from PCOS and/or cardiovascular risk factors including: general obesity, abdominal obesity, hypertension, glucose intolerance, diabetes, hyperinsulinemia, general hypercholesterolemia, hypercholesterolemia with high LDL-cholesterol levels, low HDL-cholesterol levels and hypertriglyceridemia, as well as the grouping of some of these cardiovascular risk factors known as metabolic syndrome. The method and the kit are characterized in that they are based on the detection of at least one genotype or haplotype of a polymorphism in the CAPN5 gene selected from: Nt g.86 A>G, Nt g.344 G>A, Nt c.1320 C>T and Nt c.1469 G>A or combinations thereof. | 2009-08-20 |
20090208929 | Method Of In-Vitro Detection And Quantification Of HIV DNA By Quantitative PCR - Process for the detection and quantification in-vitro of HIV DNA by quantitative PCR. The invention consists of developing pairs of oligonucleotides capable of hybridizing with fragments of the gag gene sequence present in the genome of the HIV virus. These oligonucleotides permit amplification of the viral DNA by quantitative PCR. Even in the case of samples with low viral load, the invention permits detection of the HIV DNA virus by juxtaposition either of a conventional PCR with a quantitative PCR, or with a double nested quantitative PCR, using different pairs of primers in each amplification. The invention, compared with the known methods, allows determining qualitatively and quantitatively, in-vitro, the presence of HIV DNA in samples, in a rapid, reproducible manner and with high sensitivity. | 2009-08-20 |
20090208930 | Dna decontamination method - The invention is related to a method for amplifying a methylated target nucleic acid in a sample while avoiding amplification of a non-methylated target nucleic acid by inactivating it. This is accomplished by a restriction enzyme digest after bisulfite treatment of the target nucleic acid. The invention is further related to the use of a restriction enzyme to avoid amplification of a non-methylated target nucleic acid while amplifying a methylated target nucleic acid in a sample and kits for performing the methods according to the invention. | 2009-08-20 |
20090208931 | Gene Expression Level Normalization Method, Program and System - It is an object to improve the reliability and accuracy of normalization of gene expression levels, which have been measured separately, by providing a method for the acquisition of an index of high reliability and high accuracy as an index for performing the normalization such that the gene expression levels can be compared and verified. Provided is a method for normalizing a gene expression level, which has been measured for an analysis of a gene expression, by using plural gene expression levels measured for an acquisition of an index. The method includes acquiring a correlation among the plural gene expression levels measured for the acquisition of the index, and using the thus-acquired correlation as an index for normalizing the gene expression level measured for the analysis of the gene expression. The correlation function can be obtained by using, as function values, correlations among plural gene expression levels under at least two sets of experimental conditions (numerals | 2009-08-20 |
20090208932 | Methods Of Detecting An Analyte In A Sample - The invention relates to methods for detecting an analyte in a sample. The methods rely on the activity of polymerases upon polynucleotide substrates which are linked to a molecule, for example an antibody, which binds the analyte. Activity of the polymerases can be detected by the incorporation of suitably labelled nucleotides, and/or the incorporation of hapten conjugated nucleotides capable of binding a suitably labelled ligand of the hapten. | 2009-08-20 |
20090208933 | Method For Diagnosis And/Or Prognosis Of A Septic Syndrome - The present invention relates to a method for the diagnosis/prognosis of a septic syndrome based on a biological sample from a patient, characterized in that it comprises the following steps:
| 2009-08-20 |
20090208934 | PECAM-1 GENOTYPE - The invention relates to methods of identifying inter-patient differences in genotype of PECAM- | 2009-08-20 |
20090208935 | Reagents and methods for identifying and modulating expression of tumor senescence genes - This invention identifies tumor senescence genes induced by treatment with cytotoxic agents. The invention provides reagents and methods for identifying compounds that induce expression of these cellular genes and produce cellular senescence, particularly senescence in tumor cells. The invention also provides reagents that are recombinant mammalian cells containing recombinant expression constructs that express a reporter gene under the transcriptional control of a promoter for a gene the expression of which is modulated in senescent cells, and methods for using such cells to identify compounds that modulate expression of these cellular genes. | 2009-08-20 |
20090208936 | IDENTIFICATION OF MOLECULAR INTERACTIONS AND THERAPEUTIC USES THEREOF - We report the real-time monitoring of protein-protein interactions without labeling either of the two interacting proteins, posing minimum effects on the binding properties of the proteins. In particular, the methods provide protein/aptamer complexes to probe the interactions in a competitive assay where the binding of an aptamer to its target protein is altered by a second protein that interacts with the target protein. Two signal transduction strategies, fluorescence resonance energy transfer (FRET) and fluorescence anisotropy, are described. | 2009-08-20 |
20090208937 | Recurrent gene fusions in prostate cancer - Recurrent gene fusions in prostate cancer of androgen regulated genes or housekeeping genes and ETS family member genes are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided. | 2009-08-20 |
20090208938 | Use of the MCM8 Gene for the Preparation of a Pharmaceutical Composition - The use of the human or animal MCM8 gene coding for a DNA helicase, or parts of the gene, or transcripts thereof, or antisense nucleic acids able to hybridize with part of the transcripts, or silencing RNA derived from parts of the transcripts and able to repress the MCM8 gene, or proteins or peptidic fragments translated from the transcripts, or antibodies directed against the proteins or peptidic fragments for the preparation of a pharmaceutical composition for the treatment of a human or animal pathology linked to a dysfunction of the expression of the MCM8 gene, or of human or animal cancers. | 2009-08-20 |
20090208939 | Identification of Molecular Diagnostic Markers for Endometriosis in Blood Lymphocytes - The invention comprises a method of identifying or predicting the predisposition to endometriosis in a female subject comprising determining the level of gene expression of at least one differentially-expressed gene or protein or peptide of peripheral blood leukocytes in a sample of peripheral blood leukocytes or peripheral blood in a subject to provide a first value, determining the level of gene expression of the at least one differentially-expressed gene or protein or peptide of said leukocytes in a control or reference standard to provide a second value, and comparing whether there is a difference between the first value and second value. | 2009-08-20 |
20090208940 | METHOD FOR DETECTING C. ALBICANS - A HWP1 gene sequence or fragment or variants thereof as a target region in a nucleic acid based assay for | 2009-08-20 |
20090208941 | Method for investigating cytosine methylations in dna - A method for sensitive and specific detection of cytosine methylation is described wherein the DNA to be analyzed is subjected to initial enrichment. More specifically, said enrichment can be effected in a methylation-specific, sequence-specific or origin-specific fashion. Thereafter, the enriched DNA is converted in a methylation-specific fashion. The converted DNA can be analyzed using various methods, particularly real-time PCR methods. | 2009-08-20 |
20090208942 | Method and Apparatus for Correlating Levels of Biomarker Products with Disease - In one aspect the invention is a method of testing for one or more colorectal pathologies or one or more subtypes of colorectal pathology (in one embodiment colorectal cancer) in a test individual by providing data corresponding to a level of products of selected biomarkers and applying the data to a formula to provide an indication of whether the test individual has one or more colorectal pathologies or one or more subtypes of colorectal pathology. In some aspects the method is computer based and a computer applies the data to the formula. In other aspects a computer system is configured with instructions that cause the processor to provide a user with the indication of whether the test individual has colorectal pathology. Also encompassed are kits for measuring data corresponding to the products of selected biomarkers which in some embodiments include a computer readable medium. Also encompassed are kits and methods of monitoring therapeutic efficacy of treatments for one or more colorectal pathologies. | 2009-08-20 |
20090208943 | Method for the High Throughput Screening of Transposon Tagging Populations and Massive Parallel Sequence Identification of Insertion Sites - Method for the identification of a gene in a transposon population, comprising isolating genomic DNA, optionally pooling the DNA, restrict the DNA in the pools using an enzyme, ligate adaptors, amplifying the adaptor-ligated fragments with primers, one of which is a primer complementary to a border of a transposon sequence, high throughput sequencing of the fragments, aligning the fragments with known sequences in a database and thereby identifying gene candidates. | 2009-08-20 |
20090208944 | ASSESSING OUTCOMES FOR BREAST CANCER PATIENTS TREATED WITH TAMOXIFEN - This document provides methods and materials related to assessing the likely outcome for mammals (e.g., humans) with cancer (e.g., breast cancer). For example, methods and materials that involve assessing a breast cancer patient's cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) genotype to determine the likelihood of the beast cancer patient to experience breast cancer relapse or death are provided. Methods and materials that involve assessing the likelihood that a breast cancer patient being treated with tamoxifen will experience side effects such as hot flashes also are provided. | 2009-08-20 |
20090208945 | Method for the Prediction of Adverse Drug Responses to Stains - The invention provides diagnostic methods and kits including oligo and/or polynucleotides or derivatives, including as well antibodies determining whether a human subject is at risk of getting adverse drug reaction after statin therapy. Still further the invention provides polymorphic sequences and other genes. The present invention further relates to isolated polynucleotides encoding a SADR gene polypeptide useful in methods to identify therapeutic agents and useful for preparation of a medicament to treat statin induced adverse drug reactions (SADR), the polynucleotide is selected from the group comprising: SEQ ID 1-35 with allelic variation as indicated in the sequences section contained in a functional surrounding like full length cDNA for SADR gene polypeptide and with or without the SADR gene promoter sequence. | 2009-08-20 |
20090208946 | Rationale, Methods, and Assays for Identifying Human and Non-Human Primate Taste Specific Genes and Use Thereof in Taste Modulator and Therapeutic Screening Assays - This invention relates to novel rationale and methods for identifying human and primate taste-specific genes, including genes involved in salty taste perception, especially human salty taste perception, but also genes involved in sweet, bitter, umami, and sour taste perception, and genes involved in other taste cell or taste receptor related activities such as digestive function and digestive related diseases, taste cell turnover, immunoregulation of the oral and digestive tract, and metabolic regulation such as in diabetes and obesity, the genes identified using these methods, and assays for identifying taste modulators (enhancers or blockers) and potential therapeutics using these genes. These compounds have potential application in modulating (enhancing or blocking) taste perception, especially salty taste perception and as potential therapeutics. In addition, this invention relates to novel methods for identifying taste-specific genes that can be used as markers for different taste cell types, including sweet, bitter, umami, sour, salty, and other taste cells in mammals as well as assays that measure the activity of the sweet, bitter, umami, or sour receptor in the presence of these genes to identify modulators of sweet, bitter, umami, and sour taste and to identify therapeutics especially for treating digestive or metabolic disorders, taste loss, and oral infections. Particularly, the genes identified herein and antibodies or oligos thereto can be used as markers to identify and/or purify specific taste cells e.g., from taste cell suspensions by use of FACS or magnetic bead cell selection or other known cell purification and isolation procedures. | 2009-08-20 |
20090208947 | PRIMERS, METHODS AND KITS FOR AMPLIFYING OR DETECTING HUMAN LEUKOCYTE ANTIGEN ALLELES - The present invention describes primers, methods and kits for amplifying and identifying HLA alleles. Using these primers, all HLA alleles at a single locus can be amplified using either a multiplex or non-multiplex PCR approach. Within sets of the primers, control primer pairs may be used to produce control amplicons of a predetermined size from an HLA allele only if a particular HLA locus is present in the sample. The present invention further describes primers for sequencing HLA alleles following amplification. Methods and kits for using the primers are also disclosed. | 2009-08-20 |
20090208948 | DETECTION OF TOXIGENIC STRAINS OF CLOSTRIDIUM DIFFICILE - Primers and probes for detection of toxin-producing (toxigenic) strains of | 2009-08-20 |
20090208949 | PHOSPHATIDYLINOSITOL PHOSPHATE KINASE TYPE I GAMMA SPLICE VARIANTS AS BIOMARKERS AND DRUG TARGETS FOR EPITHELIAL CANCERS - The present invention relates generally to the field of phosphatidylinositol based signaling pathways, and more specifically to the use of novel members of these pathways for disease prognosis and treatment. In some aspects, the present invention relates to the use of novel splice variants of type I phosphatidylinositol phosphate kinase γ, named PIPKIγ 700 and PIPKIγ 707, to determine breast cancer and breast cancer prognosis. | 2009-08-20 |
20090208950 | METHODS OF IDENTIFYING AN ORGANISM FROM A HETEROGENEOUS SAMPLE - This disclosure features methods of identifying at least one organism from a heterogeneous sample. The methods include: (a) obtaining a nucleic acid from at least one organism in a heterogeneous sample; (b) imaging said nucleic acid; (c) obtaining a restriction map of said nucleic acid; and (d) correlating the restriction map of said nucleic acid with a restriction map database, thereby identifying at least one organism in the heterogeneous sample. | 2009-08-20 |
20090208951 | DETECTION OF T-DNA - The present invention relates to a method for the detection of transgenic DNA (tDNA) in a living being and to a kit for performing such a method. | 2009-08-20 |
20090208952 | UTILITY OF RET MUTANT IN DIAGNOSIS AND TREATMENT OF MELANOMA - The invention relates to a method of detecting a RET mutant in a melanoma cell. Also disclosed is a method of modulating the activity of a RET mutant in a melanoma cell with an agent that interferes with the activity of the RET mutant. | 2009-08-20 |
20090208953 | NEUROFIBROMIN PATHWAY MODULATORS - The present invention encompasses methods for treating neurofibromatosis and methods for screening for modulators of the neurofibromin pathway. | 2009-08-20 |
20090208954 | PRIMER SET FOR AMPLIFICATION OF UGT1A1 GENE, REAGENT FOR AMPLIFICATION OF UGT1A1 GENE CONTAINING THE SAME, AND THE USES THEREOF - Primer sets for amplifying target regions containing sites to be detected in the UGT1A1 gene by a gene amplification method are provided, wherein the primer sets can amplify the regions specifically. Three pairs of primer sets are used including forward primers consisting of the base sequences of SEQ ID NOs: 4 or 81, 21, and 42 as well as reverse primers consisting of the base sequences of SEQ ID NOs: 13 or 91, 29 and 48, respectively. The use of these primer sets makes it possible to amplify three target regions including parts where three types of polymorphisms (UGT1A1*6, UGT1A1*27, and UGT1A1*28) of the UGT1A1 gene are generated, respectively, in the same reaction solution at the same time. | 2009-08-20 |
20090208955 | METHODS FOR IDENTIFYING SEQUENCE MOTIFS, AND APPLICATIONS THEREOF - The present invention relates to methods and algorithms that can be used to identify sequence motifs that are either under- or over-represented in a given nucleotide sequence as compared to the frequency of those sequences that would be expected to occur by chance, or that are either under- or over-represented as compared to the frequency of those sequences that occur in other nucleotide sequences, and to methods of scoring sequences based on the occurrence of these sequence motifs. Such sequence motifs may be biologically significant, for example they may constitute transcription factor binding sites, mRNA stability/instability signals, epigenetic signals, and the like. The methods of the invention can also be used, inter alia, to classify sequences or organisms in terms of their phylogenetic relationships, or to identify the likely host of a pathogenic organism. The methods of the present invention can also be used to optimize expression of proteins. | 2009-08-20 |
20090208956 | PRIMER SET FOR AMPLIFYING CYP2C9 GENE, REAGENT FOR AMPLIFYING CYP2C9 GENE CONTAINING THE SAME, AND THE USES THEREOF - A primer set for amplifying a region including a site to be detected of CT2C9*3 in the C-YT2C9 gene by a gene amplification method is provided, wherein the primer set can amplify the region specifically. A pair of primer set is used including a forward primer consisting of the base sequence of SEQ ID NO: 4 as well as a reverse primer consisting of the base sequence of SEQ ID NO: 17. The use of this primer set makes it possible to specifically and efficiently amplify a target region including the site where a polymorphism, CYP2C9*3, of the CYP2C9 gene is generated. | 2009-08-20 |
20090208957 | Alternate labeling strategies for single molecule sequencing - Systems and methods of enhancing fluorescent labeling strategies as well as systems and methods of using non-fluorescent and/or non-optic labeling strategies, e.g., as with single molecule sequencing using ZMWs, are described. | 2009-08-20 |
20090208958 | METHODS AND KITS FOR DETECTING SINGLE NUCLEOTIDE POLYMORPHISMS OF CHROMOSOME IMPLICATED IN PREMATURE CANITIES - Methods and kits for diagnosing a predisposition to premature canities in an individual are disclosed. A method for diagnosing a predisposition to premature canities in an individual comprises detecting at least one SNP marker of the human chromosome 9, selected from the group consisting of rs306534, rs3739902, rs575916, and rs365297. A kit for diagnosing a predisposition to premature canities comprises a means for detecting in a sample of human genetic material, the allele of a SNP marker of the human chromosome 9 selected from the markers rs306534, rs3739902, rs575916 and rs365297; and a positive or negative control. | 2009-08-20 |
20090208959 | FLUORESCENCE-LABELED OLIGONUCLEOTIDE TO DETECT NUCLEIC ACID AND METHOD FOR ACQUIRING INFORMATION ABOUT DOUBLE-STRAND FORMATION BY USING FLUORESCENCE-LABELED OLIGONUCLEOTIDE TO DETECT NUCLEIC ACID - A fluorescence-labeled oligonucleotide to detect nucleic acid has a base sequence complementary to the nucleic acid chain to be detected and changes in fluorescence characteristics upon double-strand formation with the nucleic acid chain to be detected. The label is an intercalating fluorescent dye and a non-intercalating fluorescent dye. The intercalating fluorescent dye acquires excited energy upon absorption of light and gives it to the non-intercalating fluorescent dye, and the non-intercalating fluorescent dye receives the excited energy to emit light. | 2009-08-20 |
20090208960 | METHODS FOR IDENTIFYNG CELLULAR MODULATORS OF DISAGGREGATION ACTIVITY OR AGGREGATION ACTIVITY IN AN ANIMAL - Methods for identifying a cellular modulator of a biological disaggregation activity or a biological aggregation activity of an animal are provided. Methods for identifying a compound which modulates biological disaggregation activity or a biological aggregation activity in a biological sample are provided. | 2009-08-20 |
20090208961 | COMPOSITIONS AND METHODS FOR USE IN ANALYTICAL REACTIONS - Compositions, methods, substrates and systems for use in analysis of single molecule reactions and particularly single molecule nucleic acid sequence analysis. Compositions that include non-reactive, distinguishable or undetectable competitive substrates for the reaction system of interest are provided, as well as their use in systems and substrates for such applications, such compounds typically preferably polyphosphate chains or analogous structures. | 2009-08-20 |
20090208962 | MARKERS FOR BREAST CANCER - Correlations between polymorphisms and breast cancer are provided. Methods of diagnosing, prognosing, and treating breast cancer are provided. Systems and kits for diagnosis, prognosis and treatment of breast cancer are provided. Methods of identifying breast cancer modulators are also described. | 2009-08-20 |
20090208963 | Gene Involved in V(D)J recombination and/or DNA repair - The invention relates to a new gene and protein involved in V(D)J recombination and repair. The invention also relates to methods of diagnosis and therapy using these genes and protein. The invention also relates to transgenic animals over- and under-expressing said gene. | 2009-08-20 |
20090208964 | Soybean Polymorphisms and Methods of Genotyping - Polymorphic soybean DNA loci are useful for genotyping between at least two varieties of soybean. Sequences of the loci are useful for designing primers and probe oligonucleotides for detecting polymorphisms in soybean DNA. Polymorphisms are useful for genotyping applications in soybean. The polymorphic markers are useful to establish marker/trait associations, e.g. in linkage disequilibrium mapping and association studies, positional cloning and transgenic applications, marker-aided breeding and marker-assisted selection, and identity by descent studies. The polymorphic markers are also useful in mapping libraries of DNA clones, e.g. for soybean QTLs and genes linked to polymorphisms. | 2009-08-20 |
20090208965 | AUTOMATED METHOD FOR DETECTING CANCERS AND HIGH GRADE HYPERPLASIAS - Automated methods for detecting cancer and related hyperplasias in biological samples. | 2009-08-20 |
20090208966 | METHOD FOR REMOVING A FLUID SUBSTANCE FROM A CLOSED SYSTEM - A cap which can form an essentially leak-proof seal with an open-ended vessel capable of receiving and holding fluid specimens or other materials for analysis. To minimize potentially contaminating contact between a fluid sample present in the vessel and humans or the environment, the present invention features a cap having a frangible seal which is penetrable by a plastic pipette tip or other fluid transfer device. The cap further includes a filter for limiting dissemination of an aerosol or bubbles once the frangible seal has been pierced. The filter is positioned between the frangible seal and a retaining structure. The retaining structure is positioned on the cap above the filter and may be used to contain the filter within the cap. The material of the retaining structure may be penetrable by a fluid transfer device. | 2009-08-20 |
20090208967 | Genetic Polymorphisms As Predictive Diagnostics For Adverse Drug Reactions (ADR) And Drug Efficacy - The invention provides diagnostic methods and kits including oligo and/or polynucleotides or derivatives, including as well antibodies determining whether a human subject is at risk of getting adverse drug reaction after statin therapy or whether the human subject is a high or low responder or a good a or bad metabolizer of statins. The invention provides further diagnostic methods and kits including antibodies determining whether a human subject is at risk for a cardiovascular disease. Still further the invention provides polymorphic sequences and other genes. | 2009-08-20 |
20090208968 | COMPOSITIONS AND METHODS FOR DETECTION OF HEPATITIS A VIRUS NUCLEIC ACID - Nucleic acid oligomeric sequences and in vitro nucleic acid amplification and detection methods for detecting the presence of HAV RNA sequences in samples are disclosed. Kits comprising nucleic acid oligomers for amplifying and detecting HAV nucleic acid sequences are disclosed. | 2009-08-20 |
20090208969 | Polynucleotides and Polypeptides Encoding Receptors - Receptor polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing receptor polypeptides and polynucleotides in the design of protocols for the treatment of diseases and diagnostic assays for such conditions. | 2009-08-20 |
20090208970 | Probe for detection and quantification of inositol-1,4,5-trisphosphate and a method for detecting and quantifying inositol-1,4,5-trisphosphate using the same - A probe for detection and quantification with high accuracy in a noninvasive manner as to where and when inositol-1,4,5-trisphosphate is generated in living cells, and a method for detecting and quantifying inositol-1,4,5-trisphosphate using the probe. | 2009-08-20 |
20090208971 | Insulin promoter factor 1 as target/marker of beta cell failure - The present invention relates to the monitoring of disease progression and diagnosis of beta-cell failure in diabetes by measuring levels of IPF-1 in a liquid sample, and to screening for novel compounds for the prevention and/or treatment of diabetes. | 2009-08-20 |
20090208972 | CYTOTOXIC PROTEIN AND UTLIZATION THEREOF - This invention relates to a new cytotoxic protein (M toxin, mucous layer devastating toxin) produced by | 2009-08-20 |
20090208973 | Methods to identify compounds useful for the treatment of proliferative and differentiative disorders - The present invention relates to the discovery, identification and characterization of nucleotides that encode novel substrate-targeting subunits of ubiquitin ligases. The invention encompasses nucleotides encoding novel substrate-targeting subunits of ubiquitin ligases: FBP1, FBP2, FBP3, FBP4, FBP5, FBP6, FBP7, FBP8, FBP9, FBP10, FBP11, FBP12, FBP13, FBP14, FBP15, FBP16, FBP17, FBP18, FBP19, FBP20, FBP21, FBP22, FBP23, FBP24, and FBP25, transgenic mice, knock-out mice, host cell expression systems and proteins encoded by the nucleotides of the present invention. The present invention relates to screening assays that use the novel substrate-targeting subunits to identify potential therapeutic agents such as small molecules, compounds or derivatives and analogues of the novel ubiquitin ligases which modulate activity of the novel ubiquitin ligases for the treatment of proliferative and differentiative disorders, such as cancer, major opportunistic infections, immune disorders, certain cardiovascular diseases, and inflammatory disorders. The invention further encompasses therapeutic protocols and pharmaceutical compositions designed to target ubiquitin ligases and their substrates for the treatment of proliferative disorders. | 2009-08-20 |
20090208974 | Human Neuronal Attachment Factor-1 - A human F-spondin-like protein and DNA (RNA) encoding such protein and a procedure for producing such protein by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for treating spinal cord injuries and damage to peripheral nerves by promoting neural-cell adhesion and neurite extension, inhibiting tumor metastases and tumor angiogenesis, and stimulating wound repair. Antagonists are also disclosed which may be utilized to prevent malaria. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example, cancer, are also disclosed. | 2009-08-20 |
20090208975 | Device and methods for detecting a target cell - The present invention relates to devices for detecting intact target cells in a sample comprising a detection zone comprising an immobilized specific binding reagent, capable of forming a complex with a target analyte on a target cell. Once labeled, detection of the label indicates the absence, presence and/or amount of the target cell in a sample. The embodiments further relate to kits comprising the devices, and methods of using the devices to screen for the presence, absence, and/or amount of a target cell in a sample. | 2009-08-20 |
20090208976 | Regulation of F1-ATPase Beta Subunit Cellular Location - It has been discovered that the ability of analogues to affect binding of a labeled β-casomorphin (an enterostatin antagonist) to recombinant rat F | 2009-08-20 |
20090208978 | Panel Cell Used for Granulocyte Antibody Detection - A panel cell for detecting anti-HNA antibody is disclosed. The panel cell is obtained by introducing a DNA coding for an HNA antigen corresponding to the anti-HNA antibody into a cell so as to enable the expression of the DNA under the condition for use in the detection procedure, wherein the cell for DNA introduction exhibits no detectable reaction with anti-HLA-ABC antibody, anti-HLA-DR antibody, anti-HLA-DQ antibody, anti-HLA-DP antibody, anti-HNA-1 antibody, anti-HNA-2a antibody, anti-HNA-3a antibody, anti-HNA-4 antibody, anti-HNA-5 antibody, and serum from normal subject, in the detection procedure. The panel cell allows accurate and rapid detection of granulocyte antibody. | 2009-08-20 |
20090208979 | Method for identifying antipsychotic drug candidates - The present invention provides a method for identifying a compound or a combination of compounds having a pharmacological behavior that qualifies it as a candidate for clinical development of a drug for treatment of a psychiatric disease or disorder, preferably schizophrenia. According to this method, a candidate drug is assessed for its ability to produce a biochemical profile, in either or both in vitro and in vivo test systems, which is similar to a unique reference biochemical profile obtained following treatments with drugs or drug combinations effective against both positive and negative symptoms of psychiatric diseases or disorders. | 2009-08-20 |
20090208980 | METHOD OF IDENTIFYING CANCER BIOMARKERS AND CANCER PROGRESSION - An efficient method for identifying important cancer biomarkers and identifying progression of bladder cancer using pro-u-PA as a clinical tool is provided. Searching for biomarkers critical for bladder carcinoma diagnosis and prognosis, secreted proteomes of highly malignant U1 and pre-malignant U4 cell lines are first analyzed. Proteins in the cultured media of the U1 and U4 cell-lines were systematically examined by SDS-PAGE combined with MALDI-TOF mass spectrometry. Expression of pro-u-plasminogen activator (pro-u-PA) was confirmed by Western blot analysis and further evaluated. A statistically significant relationship between the low level and absence of pro-u-PA in urine with high stages and grades of the tumor samples was established. Constitutive expression of Ras dominant negative protein led to increased expression of pro-u-PA in cultured media, indicating the loss of pro-u-PA is associated with oncogenic transformation. The loss of pro-u-PA in urine has been identified as a marker of more advanced bladder carcinoma. | 2009-08-20 |
20090208981 | Method for Analysis of Interaction Between Small Molecules and Cells and Apparatus thereof - A method and an apparatus are provided for analyzing the interaction between small molecules and cells without using density gradient and antibody but using a column packed with identical resin particles. The interactions between cell surface and resin particles resulting in the different retention time of cells treating by different small molecules in the column contributed to examining whether the small molecule could interact with cell or not. This invention can also apply small molecule screening, drug screening through examining the retention time by using the column. | 2009-08-20 |
20090208982 | ASSAY METHOD FOR HUMAN OROTATE PHOSPHORIBOSYLTRANSFERASE PROTEIN - To establish an immunoassay method for human OPRT. | 2009-08-20 |
20090208983 | Diagnose device for measuring the ratio of proteins with similar structure - The present invention relates to a diagnostic device for measuring the ratio of similar structural proteins among the proteins secreted in a liquid test sample taken from diagnosis subject. In further detail, the test device according to the present invention comprises detection marker-antibody conjugate recognizing the same site on two or more similar structural proteins and a detection zone in which antibody specifically recognizes each of said proteins via formation of sandwich type complex, wherein said antibodies form a set, and the present Invention relates to a diagnostic device for early diagnosis of polycystic ovary syndrome, abnormal pregnancy, prostatic carcinoma etc. based on determination of the ratio of follicle stimulating hormone and luteinizing hormone in case of polycystic ovary syndrome, the ratio between hCG isomers in case of abnormal pregnancy, and the ratio of prostate-specific antigens (PSA) in case of prostatic carcinoma. | 2009-08-20 |
20090208984 | DETECTION OF FOOD SPECIFIC HUMAN IgG4 ANTIBODIES - This invention particularly discloses an improved immunoassay method for the sensitive and specific detection of food specific human IgG4 antibodies. A sample diluent comprising a chaotrophic agent is used to reduce the occurrence of nonspecific antibody-dietary antigen interactions. To reduce competition between IgE and IgG4 antibodies for specific epitopes on dietary antigens a heat denaturing step is included to inactivate IgE antibodies. Finally, a signal amplification step is included in the assay to reduce the amount of sample required to perform the assay. | 2009-08-20 |
20090208985 | Method Of Evaluating Degree Of Skin Sensitivity Using Squamous Cell Carcinoma Antigen As An Indicator Thereof - The present invention provides a method for evaluating the degree of skin sensitivity by using the expression of squamous cell carcinoma antigen (SCCA) in skin corneocytes as an indicator thereof. | 2009-08-20 |
20090208986 | Method and kit for diagnosing acute myocardial infarction - Disclosed herein are method and kit for diagnosing acute myocardial infarction which is capable of predicting and diagnosing whether coronary artery disease is proceed to myocardial infarction or not by using an increase in triglyceride level in high density lipoprotein (HDL) or low density lipoprotein (LDL), a decrease in cholesterol level in HDL, increase of interleukin-6, CETP (cholesteryl ester transfer protein) and apo (apolipoprotein) C-III as a biomarker that are characteristic changes occurred only in sera of myocardial infarction patients among patients with coronary artery disease. | 2009-08-20 |
20090208987 | Method and Composition for Stabilizing Liquid Reagents - The invention relates to methods and compositions for removing a dissociated species from a fluid medium solution during and after it has detached from a solid-phase immersed in said medium, thereby allowing the concentration of free species to remain close to zero, and for improving the signal to noise ratio in assays. This is achieved by employing a substrate, such as a scavenging solid-phase, having an attached binding partner or partners (“scavenger”) for the specifically binding species and which is present during storage. This substrate may also contain regions for binding signal generating components attached to the solid-phase. This substrate binds any free species bleeding off the solid phase, increasing the reliability and sensitivity of assays. A subset of the substrates in the invention additionally forms cross-linked networks of solid-phase particles that further increase the sensitivity of assays. | 2009-08-20 |
20090208988 | Protocol and Apparatus for Determining Heparin-induced Thrombocytopenia - A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis parameters. The measured blood hemostasis parameters permit determination of heparin-induced thrombocytopenia II complex (HiT II). | 2009-08-20 |
20090208989 | Fluorescence Spectropscopy In Absorbing Media - The invention relates to processes and devices for detecting an analyte in a sample by fluorescence measurement. | 2009-08-20 |
20090208990 | HUMAN PROTEIN ACYL TRANSFERASES AND METHODS OF USES THEREFOR - The present invention provides the identification of human Ras palmitoyl acyl transfersase complexes, and nucleic acids coding therefor. In addition, methods of screening for modulators of human Ras palmitoyl acyl transfersase, including high throughput yeast screens, are also provided. | 2009-08-20 |
20090208991 | Prediction of bone marrow toxicity - The likelihood that a compound will exhibit bone marrow toxicity in an in vivo assay predicted by the ability of the compound to inhibit at least eight kinases from a selected group. | 2009-08-20 |
20090208992 | PARAOXONASE 1 ENZYMATIC ACTIVITY, A RISK INDICATOR FOR MAJOR ADVERSE CARDIOVASCULAR EVENTS - Provided herein are methods for assessing the risk a subject or patient without significant evidence of cardiovascular disease has of experiencing a major adverse cardiac event or requiring revascularization near term. Also provided are methods of determining whether a subject who has experienced a major adverse cardiac event is at risk of experiencing a recurrent major adverse cardiac event near term. The present methods comprise determining the levels of paraoxonase 1 enzymatic activity in the blood, serum, plasma, or any combination of said bodily fluids in the subject. | 2009-08-20 |
20090208993 | Peptide substrates recognisable by a botulinum toxin a, bont/a and the use thereof - The present invention relates to a peptide substrate selectively recognized by botulinum toxin type A, BoNT/A, comprising a Nop-(Z)-Pya fragment in the peptide structure thereof, wherein Z represents an amino acids chain, preferably RA, said fragment being cleaved by said toxin. Said invention also relates to the substrate use, in particular for carrying out methods for detecting, identifying and/or dosing botulinum toxin type A, at very low concentrations (of the order of 20 pg), or inhibitors and/or activators of the metallopeptidase activity of said toxin and thereby making it possible to quantify the power thereof. | 2009-08-20 |
20090208994 | GENETIC INCORPORATION OF 3-AMINOTYROSINE INTO REDUCTASES - This invention provides reductase proteins that comprise NH | 2009-08-20 |
20090208995 | PRO-CLOTTING ENZYME, AND METHOD FOR DETECTION OF ENDOTOXIN OR (1-3)-BETA-D-GLUCAN USING THE SAME - Objects of the present invention are to provide a DNA fragment encoding a | 2009-08-20 |
20090208996 | Method and Kit for Detecting Microorganisms On A Household Surface - This invention is directed to a method and kit for detecting microorganisms on a surface. The invention involves contacting a household surface with a cleaning composition comprising hydrogen peroxide and then placing an acoustic device in close proximity to the household surface to determine if the microorganisms are still present. | 2009-08-20 |
20090208997 | GPR18 as a Biomaker for TH1 Mediated Immune Response - The present invention provides the use of GPR18 in diseases or disorders mediated by Th1 cell activation. | 2009-08-20 |
20090208998 | D/P CREATININE MARKER, METHOD OF DETERMINING D/P CREATININE, AND INTENDED USE THEREOF - A method of indirectly determining D/P creatinine for easily judging a peritoneal function is provided that does not require blood sampling or multiple recoveries of dialysis effluent. The method includes preparing a dialysis effluent obtained by peritoneal dialysis, measuring at least one protein marker selected from the group consisting of prealbumin, haptoglobin, alpha 1-microglobulin, C4, and total protein that are contained in the dialysis effluent, and determining D/P creatinine indirectly from the correlation equation that represents the relationship between the marker concentration and the D/P creatinine value that has been prepared beforehand. Furthermore, the PET category is determined indirectly from the D/P creatinine, which has been determined indirectly, based on the known reference value. | 2009-08-20 |
20090208999 | Crystalline amoxicillin trihydrate powder - The invention relates to crystalline amoxicillin trihydrate powder having a bulk density higher than 0.45 g/ml. The invention also relates to a process for preparing crystalline amoxicillin trihydrate powder, said process comprising: crystallizing amoxicillin trihydrate from a solution containing dissolved amoxicillin; separating the crystals from said solution; and drying the separated crystals, resulting in crystalline powder having a bulk density higher than 0.45 g/ml. | 2009-08-20 |