33rd week of 2010 patent applcation highlights part 45 |
Patent application number | Title | Published |
20100210649 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS - The present invention is directed to pyridazinone compounds of formula (I) and furan compounds of formula (II), pharmaceutical compositions of compounds of formula (I) and (II), kits containing these compounds, methods of syntheses, and a method of treatment of a proliferative disease in a subject by administration of a therapeutically effective amount of a compound of formulae (I) or (II). Both classes of compounds were identified through screening of a collection of small molecule libraries. | 2010-08-19 |
20100210650 | ISOXAZOLE COMPOUND FOR THE TREATMENT OF CANCER - The use of 5-(2,4-Dihydroxy-5-isopropyl-phenyl)-4-(4-morpholin-4-ylmethyl-phenyl)-isoxazole-3-carboxylic acid ethylamide or a tautomer thereof or a pharmaceutically acceptable salt or a hydrate or a solvate for the treatment of cancer of the bladder, the colon, the liver, the lung, the breast, the vagina, the ovaries, the pancreas, the kidney, the stomach, the gastrointestinal tract, the prostate, the head and neck, the peritoneal cavity, the thyroid, the bone, the brain, the central nervous system and/or the blood and/or for the treatment of myelodysplastic syndrome, systemic mastocytosis, von Hippel-Lindau syndrome, multicentric Castleman disease and/or psioriasis. | 2010-08-19 |
20100210654 | NOVEL P2Y12 RECEPTOR ANTAGONISTS - The present invention relates to novel P2Y | 2010-08-19 |
20100210660 | Heterocyclic FXR Binding Compounds - The present invention relates to compounds which bind to the NRI H4 receptor (FXR) and act as agonists or partial agonists of the NR1 H4 receptor (FXR). The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds, and to a process for the synthesis of said compounds. | 2010-08-19 |
20100210665 | DIARYLHYDANTOIN COMPOUNDS - The present invention relates to diarylhydantoin compounds, including diarylthiohydantoins, and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer. | 2010-08-19 |
20100210666 | METHODS OF USING A G PROTEIN-COUPLED RECEPTOR TO IDENTIFY PEPTIDE YY (PYY) SECRETAGOGUES AND COMPOUNDS USEFUL IN THE TREATMENT OF CONDITIONS MODULATED BY PYY - The present invention relates to methods of using GPR119 receptor to identify peptide YY (PYY) secretagogues and compounds useful in the treatment of conditions modulated by PYY, such as conditions modulated by stimulation of NPY Y2 receptor (Y2R). Agonists of GPR119 receptor are useful as therapeutic agents for treating or preventing a condition modulated by PYY, such as a condition modulated by stimulation of Y2R. Conditions modulated by PYY such as may be a condition modulated by stimulation of Y2R include bone-related conditions, metabolic disorders, angiogenesis-related conditions, ischemia-related conditions, convulsive disorders, malabsorptive disorders, cancers, and inflammatory disorders. | 2010-08-19 |
20100210670 | METHODS AND COMPOSTIONS UTILIZIING QUINAZOLINONES - Quinazolinones of formulae (a, b, c and d) are disclosed. They are useful for treating cellular proliferative diseases and disorders associated with KSP kinesin activity. | 2010-08-19 |
20100210671 | Quinazolinone T-Type Calcium Channel Antagonists - The present invention is directed to quinazolinone compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved. | 2010-08-19 |
20100210677 | NOVEL COMPOUND, CORRESPONDING COMPOSITIONS, PREPARATION AND/OR TREATMENT METHODS - Disclosed is a novel crystalline form of topotecan monohydrochloride pentahydrate, which is a pentahydrate of 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione monohydrochloride, corresponding pharmaceutical compositions, methods preparation and/or use thereof to treat anti-viral and/or cancer-related diseases. | 2010-08-19 |
20100210684 | Amine salt of carbostyril derivative - The invention provides an amine salt of a carbostyril derivative formed from a carbostyril derivative represented by the formula (1) [wherein R is a halogen atom; the substituted position of the side chain is 3- or 4-position in the carbostyril skeleton; and the bonding between 3- and 4-positions of the carbostyril skeleton is a single bond or a double bond] and an amine; and the invention is useful as drugs for treating various diseases, especially as aqueous formulations due to the superior water solubility and the superior pharmacologic effects. | 2010-08-19 |
20100210693 | BENZYLETHER AND BENZYLAMINO BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE - The present invention is directed to compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved. | 2010-08-19 |
20100210694 | NEW NO-DONOR ASPIRIN DERIVATIVES - The present invention refers to new NO-donors aspirin derivatives, a process for their preparation and pharmaceutical compositions containing them. | 2010-08-19 |
20100210695 | COMPOSITIONS AND METHODS FOR TREATING SKIN DISORDERS - The present invention is directed to pharmaceutical compositions formulated for topical administration comprising an inhibitor of carnitine palmitoyl transferase (CPT1) and methods for treating skin disorders, such as psoriasis, by administration of a CPT1 inhibitor. In particular embodiments, the invention provides a pharmaceutical composition formulated for topical administration comprising the CPT1 inhibitor ST1326. In other embodiments, the invention provides a method of treating a skin disorder, such as psoriasis by administration of the CPT1 inhibitor ST1326. | 2010-08-19 |
20100210698 | PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PESTS - A pesticidal composition comprising [2,5-dioxo-3-(2-propynyl)-1-imidazolidinyl]methyl 3-(2-methyl-1-propenyl)-2,2-dimethylcyclopropanecarboxylate and 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl 3-(2-cyano-1-propenyl)-2,2-dimethylcyclopropanecarboxylate as active ingredients, and a pests-controlling method characterized by applying an effective amount of said pesticidal composition to the pests or a locus where the pests inhabit, have an excellent controlling effect on the pests. | 2010-08-19 |
20100210710 | THERAPEUTIC siRNA MOLECULES FOR REDUCING VEGFR1 EXPRESSION IN VITRO AND IN VIVO - The invention relates to nucleic acid molecule compositions for use in modulating the expression and activity of VEGF pathway genes and decreasing unwanted neovascularization, including tumor angiogenesis, by RNA interference and methods and compositions comprising the nucleic acid molecules. | 2010-08-19 |
20100210712 | Short RNA Antagonist Compounds for the Modulation of Target mRNA - The invention provides LNA gapmer oligomers of between 10-20 nucleobases in length, which have a total of 1-3 phosphodiester internucleoside linkages. Such oligomers have been found to have superior bioavailability and have also been found to selectively accumulate in kidney cells. | 2010-08-19 |
20100210714 | Her-2/neu DNA Vaccine Having Anti-Cancer Activity - The present invention relates to human Her-2/neu expressing plasmid constructs having anti-cancer activity and a DNA vaccine comprising same for preventing and/or treating cancer. The Her-2/neu DNA vaccines of the present invention can be effectively used as a therapeutic vaccine in reducing metastasis after tumor surgery or as a prophylactic vaccine for people with genetic high risk. | 2010-08-19 |
20100210721 | POLYENYLCYCLOPROPANECARBOXYLIC ESTERS WITH HIGH INSECTICIDAL ACTIVITY - Described are new insecticide compounds that are derived from 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylic acid, also known as chrysanthemic acid, insecticidal compositions that contain the compounds, methods of synthesizing the compounds and methods of eliminating harmful insects from a substrate including bringing the substrate into contact with an effective amount of one or more such compounds. | 2010-08-19 |
20100210723 | Lipase inhibitor - An object of the present invention is to provide a fat-soluble lipase inhibitor which can contribute to prevention or treatment of obesity due to excessive fat intake or diseases caused by obesity, can be added to fats and oils of all types, and can mildly inhibit hydrolysis by lipase. The present invention is a lipase inhibitor containing, as the active ingredient, at least one substance which is a fat-soluble substance selected from among SLS type triacylglycerols (i.e., symmetric triacylglycerols composed of S which represents a short-chain fatty acid having from 2 to 6 carbon atoms and L which represents a long-chain fatty acid having from 16 to 22 carbon atoms), LUU type and UUL type triacylglycerols (i.e., asymmetric triacylglycerols composed of L which represents a long-chain saturated fatty acid having from 16 to 22 carbon atoms and U which represents an unsaturated fatty acid having from 16 to 22 carbon atoms) and glyceryl ether lipids wherein a long-chain alkyl or alkenyl chain is attached to the 1- or 3-position of the glycerin via an ether bond. | 2010-08-19 |
20100210731 | Modafinil Compositions - Polymorphs and solvates of racemic, enantiomerically pure, and enantiomerically mixed modafinil are formed and discussed. In addition, said forms are described as useful for the treatment of many conditions including, but not limited to, narcolepsy. | 2010-08-19 |
20100210734 | METHOD OF USING CALCITRIOL FOR TREATING INTRAOCULAR DISEASES ASSOCIATED WITH ANGIOGENESIS - The present invention provides a method of treating pathologies resulting from neovascular growth in the eye such as those manifested as retinopathy of prematurity, diabetic retinopathy and macular degeneration. The invention comprises the administration of an effective amount of calcitriol that is administered at doses less than toxicity and results in a significant reduction in the formation of neo-vascular growth. The invention can be used to treat existing diseases or prophylactically to treat those at risk. | 2010-08-19 |
20100210735 | Modulating the Activity of Nuclear Receptors in Order to Treat Hypoxia-Related Disorders - The subject invention provides methods for treating hypoxia-related conditions by modulating the activity of certain nuclear receptors. Specifically exemplified herein are materials and methods for treating cancer and other pathological conditions involving hypoxia and/or abnormal or excessive neovascularization. | 2010-08-19 |
20100210736 | METHOD FOR STABILIZING CALCIUM PHOSPHATES FINE PARTICLES, METHOD FOR MANUFACTURING CALCIUM PHOSPHATES FINE PARTICLES BY USING THE METHOD, AND USE THEREOF - The present invention provides a method for stabilizing fine particles of calcium phosphates without lowering their solid phase forming activity. | 2010-08-19 |
20100210739 | Slurry reactor fines segregation and removal - The embodiments of the present invention are characterized by degasifying a portion of a gas and slurry mixture in a three-phase slurry process and lowering the solids content of the degassed slurry portion to below about 20 wt %. The degassed and lowered solids content slurry portion is then introduced into a fines separation device for separation and removal of fines. The foregoing procedure has been found to increase the effectiveness of the fines separation device. | 2010-08-19 |
20100210740 | MODULAR REACTOR FOR EXOTHERMIC/ENDOTHERMIC CHEMICAL REACTIONS - Modular reactor for exothermic/endothermic chemical reactions which take place in three-phase systems, comprising a series of modules, superimposed with respect to each other, fixed to each other by means of coupling flanges, each module consisting of an external cylindrical body and a series of tube bundles, for the circulation of a thermal-exchange fluid, positioned inside said body. | 2010-08-19 |
20100210747 | COMPOSITIONS AND USE OF TRANS-1,1,1,4,4,4-HEXAFLUORO-2-BUTENE FOAM-FORMING COMPOSITION IN THE PREPARATION OF POLYISOCYANATE-BASED FOAMS - A foam-forming composition is disclosed which includes both trans-1,1,1,4,4,4-hexafluoro-2-butene and an active hydrogen-containing compound having two or more active hydrogens. Also disclosed is a closed-cell polyurethane or polyisocyanurate polymer foam prepared from reaction of effective amounts of the foam-forming composition and a suitable polyisocyanate. Also disclosed is a process for producing a closed-cell polyurethane or polyisocyanurate polymer foam comprising: reacting an effective amount of the foam-forming composition and a suitable polyisocyanate. | 2010-08-19 |
20100210749 | Oxime ester compounds and photosensitive resin compositions using the same - [Purpose] To provide highly-sensitive oxime ester compounds as photopolymerization initiators in photosensitive resin compositions. | 2010-08-19 |
20100210754 | X-ray Opaque Barium-Free Glasses and Uses Thereof - Zirconium-containing BaO— and PbO-free X-ray opaque glasses having a refractive index n | 2010-08-19 |
20100210760 | PROCESS FOR MANUFACTURING MODIFIED CONJUGATED DIENE POLYMER, COMPOSITION COMPRISING THE POLYMER, AND TIRE COMPRISING THE COMPOSITION - The present invention has an object to provide a conjugated diene-based polymer, subjected to a vulcanization treatment to make a vulcanized rubber, the vulcanized rubber useful as a material for tire treads excellent in the balance among wet skid characteristics, low hysteresis loss, abrasion resistance, breaking strength and rigidity, and to provide its manufacturing process. According to the present invention, there is provided the process for manufacturing a modified conjugated diene-based polymer having a modifying group in its molecule, the process including a step of obtaining a conjugated diene-based polymer by polymerizing a conjugated diene compound, or a conjugated diene compound and an aromatic vinyl compound, by using an alkaline metal-based initiator or an alkaline earth metal-based initiator in a hydrocarbon solvent, and a step of reacting active terminals of the polymer with a glycidylamino group-containing low molecular compound having two or more tertiary amino groups and three or more glycidyl groups bonded to the amino groups in a molecule of the compound, and an oligomer of a dimmer or more of the low molecular compound as modifying agents, wherein the reaction is performed using 75 to 95% by mass of the low molecular compound and 25 to 5% by mass of the oligomer based on the total amount of the modifying agents. | 2010-08-19 |
20100210770 | ELASTOMERIC COMPOSITE - An elastomeric composite comprising a synthetic rubber which incorporates a biofiller is provided. | 2010-08-19 |
20100210771 | METHOD FOR PRODUCING A THICKENER DISPERSION - A method is described for producing an aqueous thickener dispersion from a monomer composition made of at least one ethylenically unsaturated carboxylic acid and at least one ethylenically unsaturated hydrophobic monomer,
| 2010-08-19 |
20100210772 | NEAR-INFRARED ABSORBING COMPOSITION AND NEAR-INFRARED ABSORBING FILTER - A near-infrared absorbing composition which is imparted with a function of absorbing near-infrared rays emitted from a display such as a plasma display, capable of reducing the number of lamination steps resulting in excellent production efficiency, capable of resisting to color non-uniformity of a filter even after a long-term use at high temperature or high humidity, and capable of preventing an increase in haze, and a near-infrared absorbing filter having a near-infrared absorbing layer comprising the composition. The near-infrared absorbing composition has composite tungsten oxide fine particles which are dispersed in a resin including carboxyl groups and has an acid number of 0.6 or more and 30 or less. | 2010-08-19 |
20100210776 | Treatment Compositions for Fresh Concrete or Mortar Surfaces Which Offer Improved Adhesion Capacity and Water Retention Power - The invention relates to compositions intended, to be applied to the surfaces of freshly poured mortars and/or concretes, before the beginning of the setting, in order simultaneously to prevent the evaporation of the water present in said mortars and/or concretes, which is necessary for their setting and then for their hardening, and in order to create, on said treated surfaces, high adhesiveness for the finishing materials intended to cover them, these compositions being provided in the form of aqueous emulsions comprising at least one paraffin wax (a), alone or in combination with at least one hydrocarbon compound (b) and/or with at least one other hydrocarbon compound (c) different from the hydrocarbon compound (b), and also comprising at least one latex (d) formed of a colloidal aqueous emulsion of at least one polymer, and at least one pulverulent inorganic or organic filler (e). | 2010-08-19 |
20100210778 | CARBONATE POLYMER BLENDS WITH REDUCED GLOSS - Disclosed is a carbonate polymer blend composition comprising (a) a carbonate polymer, (b) a propylene polymer, (c) a compatibilizing graft copolymer, (d) a polymer selected from a graft modified propylene polymer and/or an alpha-olefin carboxylic acid copolymer, and/or an olefin block copolymer, optionally (e) a filler, (f) optionally a thermoplastic resin other than (a), (b), (c), or (d) and (g) optionally one or more additive selected from stabilizers, pigments, mold release agents, flow enhancers, or antistatic agents. Said carbonate polymer blend composition has a good balance of physical properties, impact resistance, process-ability, and reduced gloss in molded articles. | 2010-08-19 |
20100210783 | POLYCYCLOOLEFIN (PCO) THERMOSET ASSEMBLY AND PROCESS FOR ITS PREPARATION - The present invention relates to a polycycloolefin (PCO) thermoset network assembly and a process for its preparation obtainable by polymerising a first reactive composition comprising a norbornene-type cycloolefin monomer in the presence of a Mo- or W-catalyst to obtain a PCO-Mo/W-network and polymerising a second reactive composition comprising a nor-bornene-type cycloolefin monomer in the presence of a Ru-catalyst on said PCO-Mo/W-network to obtain a PCO thermoset network assembly. | 2010-08-19 |
20100210784 | EMULSION POLYMER COMPRISING ACTIVATORS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF IN TWO-COMPONENT OR MULTICOMPONENT SYSTEMS - Emulsion polymer which can be obtained by polymerization of a mixture. The emulsion polymer of the invention makes it possible to provide two-component or multicomponent systems which cure by means of a redox initiator system and have a controllable pot life, in which use is preferably made of two monomers which swell the emulsion polymer to different extents and of which that having a sufficient swelling action is stored separately from the emulsion polymer, preferably together with a peroxide in an organic solvent, until the system is used. The system is used in adhesives, pourable resins, floor coatings and other reactive coatings, sealing compositions, impregnation compositions, embedding compositions, compositions for producing artificial marble and other artificial stones, compositions for reactive pegs, dental compositions, porous plastic moulds for ceramic objects or in unsaturated polyester resins and vinyl ester resins. | 2010-08-19 |
20100210791 | Multimodal Polyethylene Copolymer Resin Composition, a Preparation Process Therefor and a Polymeric Product Comprising the Same - The invention relates to a multimodal polyethylene copolymer resin composition comprising (a) a lower molecular weight (LMW) ethylene polymer fraction and (b) a higher molecular weight (HMW) ethylene copolymer fraction, wherein the higher molecular weight (HMW) ethylene copolymer fraction comprises (b1) a higher molecular weight (HMW) ethylene copolymer subfraction having a weight average molecular weight at least 2 times the weight average molecular weight (Mw) of said multimodal polyethylene copolymer resin composition, which (b1) higher molecular weight (HMW) ethylene copolymer subfraction amounts from about 1-30 wt % of the total amount of the multimodal polyethylene copolymer resin composition and comprises comonomers in amount of at least about 1 wt % of the total amount of comonomer present in said multimodal polyethylene copolymer resin composition, a process for its preparation and its use. | 2010-08-19 |
20100210792 | DRUG DELIVERY - Formulations of drugs and crystalline side chain polymers to provide controlled and/or sustained release drug formulations. | 2010-08-19 |
20100210795 | GAS-PHASE PROPYLENE POLYMERIZATION PROCESS USING STAGED ADDITION OF ALUMINUM ALKYL - An olefin polymerization process comprises gas-phase polymerization of at least one olefin monomer in more than one polymerization zones using a high activity Ziegler-Natta catalyst system comprising a solid, magnesium-supported, titanium-containing component and an aluminum alkyl component comprising introducing the titanium-containing component and an aluminum alkyl component into the first polymerization zone and then introducing additional aluminum alkyl component into a subsequent polymerization zone without added titanium-containing component. | 2010-08-19 |
20100210798 | CATALYST FOR THE POLYMERIZATION OF OLEFINS - The present invention relates to catalysts systems for the polymerization of ethylene and its mixtures with olefins CH | 2010-08-19 |
20100210811 | POLYCARBONATE RESIN COMPOSITION AND METHOD OF PRODUCING THE SAME - The present invention relates to a polycarbonate resin composition which comprises a polycarbonate resin having the repeating unit that is represented by the following general formula (1) and a hydroxyl group at terminal thereof and has the concentration of the terminal hydroxyl group of 1000 ppm or more. | 2010-08-19 |
20100210813 | SYSTEM AND METHOD FOR REDUCING OFF-GASSING OF POLYPHENYLENE SULFIDE - The techniques provide a system and a method of producing polyphenylene sulfide (PPS) polymer. The PPS polymer is produced by reacting a sulfur source and a dihaloaromatic compound in the presence of a polar organic compound in a polymerization mixture in a polymerization vessel. The PPS polymer is washed with a base to lower the oligomer content of the PPS polymer and thus the off-gassing during processing. | 2010-08-19 |
20100210814 | FUSION-FREE HYDROLYSIS OF POLYPHOSPHORIC ACID IN SPUN MULTIFILAMENT YARNS - The present invention relates to processes for hydrolyzing polyphosphoric acid in spun multifilament yarns. | 2010-08-19 |
20100210822 | MODIFIED RECOMBINANT HUMAN ENDOSTATIN AND USES THEREOF - Provided is a kind of modified recombinant human endostatin that has the structure of CH | 2010-08-19 |
20100210826 | HGF BETA CHAIN VARIANTS - The invention provides HGF/Met modulators comprising HGF having mutations in regions that affect HGF function, and antagonists that target said regions. The invention further provides methods of identifying, making and using these modulators. | 2010-08-19 |
20100210827 | Preparation Method Of Recombinant Protein By Use Of A Fusion Expression Partner - The present invention relates to a preparation method using a fusion expression partner. The method includes preparing a polynucleotide encoding a fusion expression partner selected from the group consisting of SlyD (FKBR type peptidyl prolyl cis-trans isomerase). Crr (glucose-specific phosphotransferase (PTS) enzyme IIA component). RpoS (RNA polymerase sigma factor) PotD (Spermidine/putrescine-binding periplasmic protein), and RpoA (RNA polymerase alpha subunit), and an expression vector linking a polyDNA fragment of a heterologous protein, preparing a transformant by introducing the expression vector into a host cell, inducing the expression of a recombinant protein by culturing a transformant, and obtaining the expression. In the preparation method of the recombinant protein, the heterologous protein may enhance the water-solubility and folding of the recombinant protein, overcome the limitations about the water-solubility and folding which the conventional fusion expression partners have, and be used widely in the production of pharmaceutical and industrial proteins. | 2010-08-19 |
20100210832 | BIDIRECTIONAL PROMOTERS IN NANNOCHLOROPSIS - Exemplary embodiments provided herein include novel promoters isolated from the microalgae, Nannochloropsis. These promoters drive gene expression in a bidirectional manner, and are especially useful for the genetic manipulation of Nannochloropsis and other organisms. The inventors herein successfully used these promoters (in both parallel and antiparallel orientations with respect to a Sh ble gene cassette) to impart zeocine-resistance to Nannochloropsis. | 2010-08-19 |
20100210839 | SELECTIVE PHOSPHODIESTERASE 9A INHIBITORS AS MEDICAMENTS FOR IMPROVING COGNITIVE PROCESSES - The invention relates to the use of selective phosphodiesterase 9A (PDE9A) inhibitors for producing medicaments for improving perception, concentration, cognitive processes, learning and/or memory. | 2010-08-19 |
20100210846 | Process for preparing 2-(2-pyridylmethyl)-sulfinyl-1H-benzimidazoles and the intermediate compounds used therein - The present invention relates to a process for preparing 2-(2-pyridylmethyl)sulphinyl-1H-benzimidazoles that are proton pump inhibitors, using as intermediates 2-benzimidazolyl-sulphinic acid derivatives. The present invention also relates to the intermediate compounds, their use and a process for the preparation thereof. These novel intermediate compounds are 2-benzimidazolylsulphinicacid esters that are obtained from their corresponding alkaline salts, which are in turn obtained by oxidation of substituted 2-mercaptobenzimidazoles. The intermediate compounds of the invention are converted into 2-(2-pyridylmethyl)sulphinyl-1H-benzimidazoles by reaction with substituted 2-methylpyridines. | 2010-08-19 |
20100210847 | PROCESS FOR THE PREPARATION OF PANTOPRAZOLE SODIUM AND PANTOPRAZOLE SODIUM SESQUIHYDRATE - The present invention relates to a process for the preparation of pantoprazol sodium sesquihydrate of formula (I) and pantoprazole sodium. | 2010-08-19 |
20100210850 | PROCESS FOR THE PREPARATION OF 6-SUBSTITUTED-IMIDAZO [2,1-B] THIAZOLE-5-SULFONYL HALIDE - The present invention is related to the a new process for the preparation of 6-substituted-imidazo[2,1-b]thiazole-5-sulfonyl halides of formula (I), comprising gradually adding a compound of formula (II), into a heated solution of R | 2010-08-19 |
20100210851 | PROCESS FOR PREPARING OXAZOLIDINE- AND OXAZOLIDINONE-AMINODIOLS - A method of preparing oxazolidine-protected and oxazolidinone-protected aminodiol compounds is disclosed. These compounds tend to be useful as intermediates in processes for making Florfenicol and related compounds. | 2010-08-19 |
20100210861 | PROCESS AND SYSTEMS FOR INTEGRATED DEACIDIFICATION OF VEGETABLE OIL OR ANIMAL FATS AND CONVERSION OF FREE FATTY ACIDS INTO MONOHYDRIC ALCOHOL ESTERS - Methods and systems for producing both purified triacylglycerides and fatty acid-monohydric alcohol esters from a feed material comprising vegetable oil or animal fat with elevated levels of free fatty acids is disclosed. Various embodiments include adsorptive techniques. | 2010-08-19 |
20100210865 | Compounds isolated from antrodia cinnamomea and use thereof - The present invention relates to novel compounds from | 2010-08-19 |
20100210873 | METHOD FOR PRODUCING CARBOXYLIC ACID - It is an object of this invention to provide a method for efficiently synthesizing monocarboxylic acid, dicarboxylic acid, and tricarboxylic acid with the use of unsaturated triacyl glycerol as a starting material and hydrogen peroxide as an oxidant. Such method comprises allowing unsaturated triacyl glycerol to react with hydrogen peroxide in the presence of a quaternary ammonium polybasic acid hydrogen salt and at least one member selected from the group consisting of tungstic acid, heterotungstic acid, and salts thereof. | 2010-08-19 |
20100210874 | Process and Plant for Urea Production - A process for producing urea is disclosed, wherein liquid ammonia and carbon dioxide are reacted in a high-pressure synthesis section ( | 2010-08-19 |
20100210883 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUNDS - Disclosed are methods for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of formula (I): | 2010-08-19 |
20100210884 | PROCESS FOR PRODUCING PENTAFLUOROETHANE - The present invention relates to a process for producing pentafluoroethane. More particularly, the subject of the invention is a continuous process for producing pentafluoroethane comprising (i) a step of fluorinating perchloroethylene (PER) with hydrofluoric acid, in the gas phase, in the presence of a catalyst, (ii) a step of separating the products issuing from step (i) in order to give a fraction of light products and a fraction of heavy products, comprising hydrofluoric acid, unreacted perchloroethylene and under-fluorinated products, and (iii) a step of pretreating the fraction of heavy products before recycling to step (i). | 2010-08-19 |
20100210886 | Production of High Purity Ethylbenzene From Non-Extracted Feed and Non-Extracted Reformate Useful Therein - A process for producing an ethylbenzene product having a purity of at least 99.50 percent based on the weight of ethylbenzene present in the product by the ethylation of the benzene present in non-extracted feed, e.g., non-extracted hydrocarbon composition. The non-extracted feed is substantially free of both C | 2010-08-19 |
20100210892 | IMPLANTS INCLUDING SPACERS FOR USE IN BRACHYTHERAPY AND OTHER RADIATION THERAPY THAT RESIST MIGRATION AND ROTATION - A brachytherapy implant includes a plurality of protrusions to reduce a tendency of the implant to migrate and rotate within a patient's body after implantation. Embodiments of the present invention are directed to spacers that resist migration and rotation. This abstract is not intended to be a complete description of the invention. | 2010-08-19 |
20100210893 | APPARATUS AND METHOD FOR ELECTROMAGNETIC TREATMENT OF PLANT, ANIMAL, AND HUMAN TISSUE, ORGANS, CELLS, AND MOLECULES - An apparatus and method for electromagnetic treatment of plants, animals, and humans comprising: configuring at least one waveform according to a mathematical model having at least one waveform parameter, said at least one waveform to be coupled to a target pathway structure; choosing a value of said at least one waveform parameter so that said at least waveform is configured to be detectable in said target pathway structure above background activity in said target pathway structure; generating an electromagnetic signal from said configured at least one waveform; and coupling said electromagnetic signal to said target pathway structure using a coupling device. | 2010-08-19 |
20100210899 | Method for percutaneous lateral access to the left ventricle for treatment of mitral insufficiency by papillary muscle alignment - This invention relates to devices and methods for the therapeutic changing of the geometry of the left ventricle of the human heart. Specifically, the invention relates to the left-ventricular lateral wall introduction of an anchoring device to align the papillary muscles. | 2010-08-19 |
20100210901 | Devices, Systems and Methods For Diagnosing and Treating Sinusitis and Other Disorders of the Ears, Nose and/or Throat - Sinusitis, enlarged nasal turbinates, tumors, infections, hearing disorders, allergic conditions, facial fractures and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies, endoscopic studies and transillumination studies. Access and occluder devices may be used to establish fluid tight seals in the anterior or posterior nasal cavities/nasopharynx and to facilitate insertion of working devices (e.g., scopes, guidewires, catheters, tissue cutting or remodeling devices, electrosurgical devices, energy emitting devices, devices for injecting diagnostic or therapeutic agents, devices for implanting devices such as stents, substance eluting devices, substance delivery implants, etc. | 2010-08-19 |
20100210907 | INTUBATION TUBE - An interventional aid for medical interventions, including a tube body with a tube jacket which permits intubation and which, while leaving a lumen to permit ventilation, includes a functional aid for performing an interventional function. The functional aid includes an orientation mechanism orienting the tube body during the medical intervention. | 2010-08-19 |
20100210915 | SURGICAL LIFT DEVICE TO ASSIST IN SURGICAL ACCESS THROUGH SKIN, TISSUE AND ORGANS - A surgical lift device includes a suction member for detachably contacting an external skin surface of a human body wall and holding the external skin surface by application of negative pressure between the suction member and the external skin surface. The suction member has a gripping force sufficient to permit lifting of the human body wall to an elevated position and to hold the human body wall in the elevated position. The suction member has a load-bearing domed structure which determines the lifting of the human body wall during application of negative pressure. The surgical lift device further includes a low friction entry port device arranged on the dome structure, wherein the low friction entry port device has a low friction port fixture for inserting a tool. | 2010-08-19 |
20100210917 | MEANS OF DIRECT VISUALIZATION THROUGH A CURVED APPROACH PATH - A coupled pair of retractors which are coupled at the distal end to allow the handles at the proximal end to be urged apart to increase the distance between handles to allow for direct line of sight to the surgical site while also allowing the use of curved tools and curved access to the surgical site. A cannula with a cross section taken perpendicular to a straight portion of the cannula that increases between the proximal end of the cannula and the distal end of the cannula allows for direct line of sight to the surgical site while also allowing the use of curved tools and curved access to the surgical site. These tools may be used in a postero-lateral approach from an incision in the back to a target position adjacent to the spine. | 2010-08-19 |
20100210918 | TASK LIGHT - In one aspect, the invention is directed to a treatment light comprising a support member having at least two light source support portions: each support portion adapted to be operatively connected a light source; each light source comprising one or more LEDs, particularly a plurality of LEDs associated with a focusing material which focuses the LED emitted lights into cones, the at least two light sources adapted to be fixed at spaced apart positions proximate to either side of the head of a user, the support members defining a space for positioning the head of the user next to and potentially in between the at least two light sources. Preferably, the potential contact surfaces have a steady state temperature of no greater than 120 degrees Fahrenheit when tested at an ambient temperature of 72 degrees Fahrenheit. According to one embodiment of the invention, the potential contact surfaces are no hotter than 100 degrees Fahrenheit despite generating a cumulative output of 60 to 65 watts of power. | 2010-08-19 |
20100210921 | SCALE-TYPE NONCONSTRAINED HEALTH CONDITION EVALUATING APPARATUS AND METHOD - A scale-type nonconstrained health condition evaluating apparatus includes a load cell sensor for sensing a ballistocardiogram signal and a weight signal from a measured person, an electrocardiogram sensor for sensing an electrocardiogram signal from the measured person, and a signal processor for calculating at least one of the heart rate, normalized stroke volume force, blood pressure and equilibrium sense abnormality of the measured person from the ballistocardiogram, weight and electrocardiogram signals sensed by the load cell sensor and the electrocardiogram sensor. | 2010-08-19 |
20100210926 | Apparatus and Method for Detecting at Least One Vital Parameter of a Person; Vital Parameter Detection System - What is described is an apparatus for detecting at least one vital parameter of a person, including: an optoelectronic sensor arrangement for detecting the at least one vital parameter by means of light transmission or light remission, the optoelectronic sensor arrangement including a light source and a light-sensitive element, wherein for detecting the vital parameter by means of light transmission, the light source is arranged in a first side part of a support frame of a pair of spectacles, and the light-sensitive element is arranged in a second side part of the support frame which is opposite the first side part, and wherein for detecting the at least one vital parameter by means of light remission, the light source and the light-sensitive element are arranged in the same side part of the support frame of the pair of spectacles. | 2010-08-19 |
20100210930 | Physiological Blood Gas Detection Apparatus and Method - The present disclosure is directed to methods and physiological sensing devices for determining blood gas concentrations in a human or animal subject. Such devices may further detect and measure the subject's heart rate. | 2010-08-19 |
20100210935 | CHIN ADHESIVE AND METHOD FOR USE - The current invention is an apparatus that comfortably fits on an individual's chin and holds electrodes in place. | 2010-08-19 |
20100210938 | Navigation System for Cardiac Therapies - An image guided navigation system for navigating a region of a patient includes an imaging device, a tracking device, a controller, and a display. The imaging device generates images of the region of a patient. The tracking device tracks the location of the instrument in a region of the patient. The controller superimposes an icon representative of the instrument onto the images generated from the imaging device based upon the location of the instrument. The display displays the image with the superimposed instrument. The images and a registration process may be synchronized to a physiological event. The controller may also provide and automatically identify an optimized site to navigate the instrument to. | 2010-08-19 |
20100210939 | Method and Apparatus for Surgical Navigation - Disclosed is a surgical navigation system for tracking an instrument relative to a patient. The system can track a portion of the patient, an instrument, and/or both relative to image data, a coordinate system, an atlas, a morphed atlas, or combinations thereof. The system can include a tracking device on the instrument to provide six degree of freedom information regarding the location of the instrument. | 2010-08-19 |
20100210949 | ULTRASONIC TRANSMITTER/RECEIVER DEVICE, ULTRASONIC PROBE AND ULTRASONIC DIAGNOSTIC APPARATUS - The ultrasonic transmitter/receiver device comprises a transmission section which transmits ultrasonic waves generated by a piezoelectric element when a transmission signal is inputted, a reception section which is superposed directly or indirectly on the transmission section and outputs a reception signal generated by a piezoelectric element when ultrasonic waves are received, a pair of a transmission signal wire and a transmission grounding wire for supplying the transmission signal to the transmission section, and a pair of a reception signal wire and a reception grounding wire for taking the reception signal from the reception section. The transmission grounding wire and the reception grounding wire are used in common as a common grounding wire. The common grounding wire and the transmission signal wire, and further the common grounding wire and the reception signal wire are disposed on different side surfaces of the transmission section and the reception section superposed with each other. | 2010-08-19 |
20100210950 | OPTO-ELECTRICAL ULTRASOUND SENSOR AND SYSTEM - An opto-electrical ultrasound sensor, preferably for the use in medical diagnostics, comprising at least one light source ( | 2010-08-19 |
20100210951 | Optical System for Imaging of Tissue Lesions - The present disclosure, according to one embodiment, relates to an optical device for direct visualization, imaging, and spectroscopic measurements of tissue abnormalities at various anatomical sites. Such sites include, but are not limited to, the oral cavity, the cervix, and the skin. In one embodiment, the device comprises: a frame; at least one light-emitting diode light source mounted on the frame for illuminating a tissue, wherein the at least one light-emitting diode light source is chosen from a fluorescent light source, a polarized white light source, and an unpolarized white light source; at least one loupe mounted on the frame for visually observing the tissue; at least one filter disposed between the tissue and the loupe for filtering light reflected from the tissue; and an energy source operably connected to the at least one light-emitting diode light source. | 2010-08-19 |
20100210955 | DEVICE FOR TREATMENT OF ANEURYSM - In a method, system and device for treating aneurysm a member is placed around the aneurysm, the aneurysm can be treated and monitored. The member can comprise a sensor placed in relation to a wall portion of the aneurysm for generating a signal corresponding to a parameter related to the aneurysm or the treatment of the aneurism. For example the size of the aneurysm such as the diameter of the aneurysm can be monitored. Hereby changes in the aneurism can be detected and information about the changes of the aneurysm can be used when determining how to treat the aneurysm. | 2010-08-19 |
20100210965 | APPARATUS AND METHOD FOR THE DETECTION OF NEUROMUSCULAR SIGNALS - A multi-electrode assembly for use in neuromuscular testing, the multi-electrode assembly comprising: | 2010-08-19 |
20100210966 | Firing System For Biopsy Device - A biopsy system for harvesting tissue samples from a suspect tissue mass in a body of a living being, e.g. in per-cutaneous aspiration biopsy, comprises a hollow needle ( | 2010-08-19 |
20100210967 | SURGICAL KITS AND METHODS - A kit for implantation of material into a body, a kit for extraction of tissue from a body and a tissue transplantation kit. A method for implanting material into a body, a method for extracting tissue from a body and a method for transplanting tissue into a body. | 2010-08-19 |
20100210970 | PIERCING DEVICE, BLOOD INSPECTION DEVICE, AND PIERCING METHOD - A piercing device, a blood inspection device, and a piercing method that facilitate timing management for piercing. The piercing device has a housing ( | 2010-08-19 |
20100210973 | Medical pressure measuring device - A medical pressure measuring device placed upon a patient's foot for accurately measuring pounds pressure as the patient stands and ambulates includes a flexible wrap having hook and loop fastening connections, a flat load cell sensor on the wrap bottom interconnected to a readily and easily viewable digital display for showing a digital readout of pounds pressure and power for the digital display being provided by a flat lithium nickel size battery and the wrap adaptable for fitting onto adult-size or child-size feet. | 2010-08-19 |
20100210974 | AUTOMATIC DISCRIMINATION OF DYNAMIC BEHAVIOUR - There is a distributive sensing technology that can discriminate between the causes of dynamic disturbances. The system applies sensing elements within a sensing medium, and the medium couples the dynamic disturbance and the sensors. By interpreting the responses of the medium, the nature of the disturbance can be discriminated in a way as to determine a description, class or category. There is a method of categorizing the dynamic body behavior, the method comprising: providing a sensing medium during at least a period of the dynamic behavior of the body; providing a plurality of sensors coupled to the sensing medium; obtaining a sensory data time series from each sensor, the sensing medium and the sensors being arranged such that the obtained sensory data time series are not independent from one another; specifying a dynamic behavior category; and processing the sensory data time series. Apparatus for performing the method is also described. | 2010-08-19 |
20100210981 | SLIMMING APPARATUS THAT OPERATES BY IMPROVING CUTANEOUS CIRCULATION - A slimming apparatus operates by improving cutaneous circulation during activity in the fat burning pulse range carried out on endurance training equipment. The apparatus includes a main body with a fastening element in the form of a cuff which has at least two chambers that are independent of one another and that can be supplied with a fluid independent of one another. A simple configuration and high therapeutic effect can be achieved in such a way that a first chamber consists of a first main section which is arranged in a substantially linear fashion, with several first branch sections branching off from said main section. A second chamber consists of a second main section, with several second branch sections branching off from said section, which second sections are each arranged between the first branch sections. The apparatus can be attached to different body parts and includes a belt which is arranged with at least two chambers which are independent from one another. The apparatus further includes one pump for generating the alternating pressure load and a fastening cuff which press the basic body onto the human body in order to start the operation of the pressure chamber. | 2010-08-19 |
20100210982 | Method And System For Providing Segmental Gradient Compression - A system for providing segmental gradient compression to a body of a patient of the type comprising a wrap applied to an appendage of the patient. The system includes a control unit, a compression bladder, a barrier disposed within the compression bladder and defining a passive port, and first and second chambers disposed within the compression bladder. The first and second chambers are defined by the barrier and are fluidly coupled to each other via the passive port. This arrangement defines a flow path of a gas from the first chamber to the second chamber through the passive port. Inflation of the compression bladder with the gas results in sequential inflation of each chamber of the plurality of chambers thereby applying gradient circumferential pressure to the appendage of the patient. | 2010-08-19 |
20100210985 | SHOULDER ORTHOSIS - A shoulder orthosis ( | 2010-08-19 |
20100210990 | CATHETER/FISTULA NEEDLE TO BLOODLINE CONNECTION ASSURANCE DEVICE - In general, multiple embodiments of a catheter/fistula needle to bloodline connection assurance device, which secures and strengthens a connection between an extension tube end of a catheter or fistula needle and a bloodline are provided. A first embodiment of the assurance device is configured to be compatible with any industrial catheter/fistula needle female luer connector and is specifically configured for use with a bloodline connector having locking clips which are biased slightly outwardly from the bloodline connector. The first embodiment of the assurance device is cylindrical and includes clamshell halves that open rotatably about at least one hinge. The first embodiment of the assurance device includes an upper, threaded portion and a lower housing portion. The interior wall of the upper portion defines a plurality of barbs configured to engage with distal or moveable ends of the locking clips. Each locking clip is biased slightly outwardly to enable the distal or moveable end of the locking clip to fit between two respective barbs. The barbs are spaced as close together as possible to prevent any axial movement of the bloodline connector when the assurance device is engaged about the mated connectors. | 2010-08-19 |
20100211000 | Method and system for sealing percutaneous punctures - A device for sealing a puncture in a patient includes a sealing component including an elongate control member configured to pass through a puncture in skin of a patient. The sealing component also includes an expandable member disposed near a distal end of the control member, and a tip releasably attached to the elongate control member distal to the expandable member. The device also includes a sealing material delivery component including a delivery tube through which the control member of the sealing component is configured to extend. The delivery tube is configured to deliver sealing material through an opening in a distal end of the delivery tube. | 2010-08-19 |
20100211004 | MEDICINE CUP COMBINED WITH GAUGE FOR CHECKING RISK OF OBJECTS CAUSING A BABY TO CHOKE - A babycare device combines in one piece a medicine cup ( | 2010-08-19 |
20100211009 | PERFUSION CATHETER HAVING ARRAY OF FUNNEL SHAPED MEMBRANES - An agent delivery catheter configured to deliver an agent to an inner surface of a patient's body lumen wall by forming an array of cells defining agent containment chambers at multiple locations along the catheter's shaft, while minimizing ischemic conditions during the procedure. | 2010-08-19 |
20100211010 | TOPICAL ANESTHETIC AND ANTISEPTIC DISPENSING DEVICE - Embodiments of the present invention provide a topical anesthetic and antiseptic dispensing device article of manufacture. In an embodiment of the invention, the article of manufacture includes a penetrating instrument including an elongated body with first and second distal end such that at least one of the distal ends includes a penetrating edge. By way of example, the penetrating instrument can be a syringe, an IV catheter needle assembly, a pressurized tube holder configured with a needle for blood draw, or a scalpel, to name a few possibilities. The article of manufacture also includes a container coupled to the elongated body of the penetrating instrument. The container provides at least one chamber. Finally, the article of manufacture includes a nozzle connected to the container and configured to dispense pressurized content of the container responsive to activating a trigger communicating with the nozzle. | 2010-08-19 |
20100211018 | INSTRUMENT FOR SUPPRESSING DRUG CRAVING AND KIT FOR SUPPRESSING DRUG CRAVING - The kit for suppressing drug craving K is used by connecting an instrument for suppressing drug craving | 2010-08-19 |
20100211020 | LUER-TYPE NEEDLE-FREE VALVE FITTING WITH BYPASS - Embodiments of luer-type needle-free valve devices are disclosed. One of the novel aspects of the invention is its ability to transform from an open state to a closed state. The open position eliminates the potential for a differential pressure to exist between the volume connected to the inlet and outlet of the valve fitting. The closed position enables the device to maintain a differential pressure between the volume connected to the inlet and outlet of the valve fitting. The invention is useful in manufacturing sterile medical devices by allowing all surfaces to communicate with the sterilizing agent when the valve is in an open configuration when it is in a closed position. | 2010-08-19 |
20100211029 | ASPIRATION SYSTEM FOR REMOVING LIQUID OTHER THAN URINE DISCHARGED BY THE HUMAN BODY - An aspiration system for removing liquid other than urine, which liquid is discharged from the human body, comprises a disposable body interface device having a liquid collection chamber. A liquid sensor detects the presence of liquid within the chamber, and controls application of aspiration suction to remove liquid from the liquid collection region. The body interface device may be a wound dressing, and the liquid wound exudate. The aspiration suction is controlled to remove only excess wound exudate. | 2010-08-19 |
20100211030 | WOUND TREATMENT APPARATUS WITH A CONTROL SYSTEM CONNECTED TO A FLOW METER AND A PRESSURE SENSOR - Apparatus and a method are described for the provision of topical negative pressure therapy, the apparatus comprising: an aspirant pump for moving aspirated fluid through said apparatus; aspirant conduit means operably connected to a dressing covering a wound being aspirated; a waste container operably connected to the aspirant conduit and for receiving wound exudate therein; the waste container having a fluid exit port for the flow of gaseous aspirated fluid therefrom, the exit port having filter means associated therewith for preventing aspirated liquid from passing therethrough; a fluid flow path on the exit side of said waste container for the flow of aspirated gaseous fluid therethrough; | 2010-08-19 |
20100211032 | ASPIRATION SYSTEM FOR REMOVING URINE DISCHARGED BY THE HUMAN BODY, AND LIQUID SENSOR THEREFOR - An aspiration system for removing urine from the human body comprises a disposable body interface device having a liquid collection chamber. A detachable or permanently attached non-contact liquid sensor disposed outside the liquid collection chamber detects the presence of urine within the chamber. The non-contact sensor is selected from: a capacitance sensor; an ultrasonic sensor; a piezo-resonant sensor; and a temperature sensor. | 2010-08-19 |
20100211037 | ABSORBENT ARTICLE COMPRISING AN ABSORBENT ELEMENT COMPRISING A LIQUID ABSORBENT THERMOPLASTIC COMPOSITION - The present invention relates to absorbent articles, typically for feminine protection, including a topsheet, a backsheet and an absorbent element positioned between the tospheet and the backsheet, said absorbent element includes a fluid storage layer which a liquid absorbent thermoplastic composition. The absorbent thermoplastic composition is a polymeric base material having particles of water-insoluble water-swellable absorbent material dispersed therein. The liquid absorbent thermoplastic composition is configured in a plurality of unattached spaced apart zones. | 2010-08-19 |
20100211040 | APPARATUS AND METHOD FOR DISPENSING FLUID THROUGH A PORT CONNECTOR - A dispensing apparatus and method for dispensing fluid from a container is disclosed. The dispensing apparatus includes a container for storing fluid and a dispensing cap. The dispensing cap includes a bottom portion configured to be attachable to the container and a port connector including a bottom cylindrical end for attaching the port connector through a hole in the bottom portion of the dispensing cap. The dispensing cap also includes a protective cap connectable to a top cylindrical end of the port connector for providing access to the dispensing cap. A dispensing instrument is arranged to be connectable to the top cylindrical end of the port connector to retrieve liquid stored in the container attached to the dispensing cap. | 2010-08-19 |
20100211042 | Drug Delivery Device - Embodiments of the invention generally provide a device and method for minimizing injection pain and preventing needle clogging during injection of a drug formulation into skin. Generally, the invention provides a device comprising a needle having a point to penetrate skin on one end, a hub having a diameter larger than that of the needle attached to the opposite end of the needle and connectable to a housing defining a chamber for receiving a formulation, and a polymer wrap attached to the hub, wherein the polymer wrap is tapered to the needle so as to pass through skin when the point is inserted into the skin, and wherein a space between the needle and the polymer wrap lies in a flow path of the formulation into the skin, such that formulation is injected through the space between the needle and the polymer wrap. | 2010-08-19 |
20100211051 | System and method for descemet's stripping automated endothelial keratoplasty (DSAEK) surgery - The system for donor cornea implantation includes a preparation base having a well for receiving a posterior lamellar donor corneal lenticule, a cartridge disengageably mounted on the base adjacent the well, and a handle for disengageable attachment to a posterior end portion of the cartridge. In drawing the donor lenticule from the well into and through a bore or chamber of the cartridge, from the posterior end, the lenticule is caused to assume a double coil configuration. After attachment of the handle, removal of the assembly from the preparation base, and insertion of blade and adjacent body portions of the cartridge through an incision in the cornea, the coiled donor lenticule is pulled from the cartridge bore through its forward end, to uncoil automatically within the anterior chamber of the recipient's eye. | 2010-08-19 |