32nd week of 2010 patent applcation highlights part 47 |
Patent application number | Title | Published |
20100204005 | METHOD FOR STARTING THE COMBUSTION ENGINE DURING A LOAD SHIFT IN PARALLEL HYBRID VEHICLES - A method for starting the internal combustion engine, in parallel hybrid vehicles, in which the internal combustion engine is started, during a shift under load in purely electric driving operation, by the electric machine. | 2010-08-12 |
20100204006 | METHOD FOR THE OPERATION OF A DRIVE TRAIN - A method of operating a drive train comprising a hybrid drive with a combustion engine and an electric motor; a transmission positioned between the hybrid drive and the output; and a clutch positioned between the combustion engine and the electric motor. When the electric motor exclusively drives the vehicle, the combustion engine can be started by engaging the clutch. At the time when the electric motor permanently or without traction force interruption is coupled to the output, and the rotational speed of the electric motor is greater than the starting rotational speed of the combustion engine, and a clutch, positioned between the combustion engine and the electric motor, is engagedly and disengagedly controlled so that the clutch is brought into slippage, via partial engagement, to start the combustion engine, and thereafter the clutch is completely disengaged before reaching a synchronous rotational speed between the combustion engine and the electric motor. | 2010-08-12 |
20100204007 | METHOD FOR CONTROLLING AN AUTOMATIC TRANSMISSION OF A MOTOR VEHICLE - A method of controlling an automatic transmission of a vehicle in which a hold gear function is activated by a driver request and is deactivated independently of a return condition. To allow an effective, safe to operate, and comfortable use, the return condition depends on one of the following criteria or a useful combination of the same: a flexible time span, consideration of the vehicle stand still time; a rotational speed of the vehicle engine, or one or several parameters which correlate with the engine rotational speed, a new, the same, or a different drive request by the driver, a change in the operating condition of the vehicle, and a plausibility check occurring during the startup procedure. | 2010-08-12 |
20100204008 | Hydraulic Pressure Supply Device for Industrial Vehicle - A first hydraulic circuit leads, as clutch control pressure, pressurized oil supplied from a first hydraulic pump, to a transmission control device after regulating the pressurized oil, and leads, as torque converter operation oil, pressured oil to a torque converter, and leads pressurized oil to an oil cooler. Through a second hydraulic circuit, pressurized oil from a second hydraulic pump is distributed to a circuit portion downstream of the pressure regulation valve and upstream of a safety valve and to a circuit portion downstream of the torque converter and upstream of the oil cooler. A flow control device changes a proportion of a rate of flow in the second hydraulic circuit so that a proportion of the rate of flow to the circuit portion downstream of the torque converter and upstream of the oil cooler increases as pressure at an entrance of the torque converter increases. | 2010-08-12 |
20100204009 | HYDRAULIC CONTROL DEVICE OF AUTOMATIC TRANSMISSION - A dual purpose pressure adjusting valve provides a hydraulic pressure upon failure of electric power supply and controls the hydraulic pressure selectively directed toward a high clutch and a low & reverse brake using a line pressure, that bypasses a manual valve, as a source pressure. A switching valve switches hydraulic pressure feeding passages of the high clutch and low & reverse brake in response to selection of a range position between D-range position and R-range position. A first rotation member and a transmission input shaft are connected to each other when the high clutch is engaged. The first rotation member is a member other than a transmission output gear. A high clutch inhibitor valve uses D-range pressure PD as a signal pressure and is arranged between the switching valve and the high clutch. The high clutch inhibitor valve opens a communication between the dual purpose pressure adjusting valve and the high clutch when the signal pressure is applied thereto and doses the communication between the dual purpose pressure adjusting valve and the high clutch when the signal pressure is not applied thereto. | 2010-08-12 |
20100204010 | METHOD AND DEVICE FOR CONTROLLING A CLUTCH - A method and a device for controlling a clutch, for example an automatic friction clutch forming part of a drive train of a motor vehicle, for a torque transfer between an engine and a transmission, with the clutch having significant clutch way points assigned to it. For achieving the operational readiness of the clutch over the shortest possible time period, whereby an accurate clutch adjustment is still guaranteed, a clutch way point coordinate system is monitored by checking the point of engagement of the clutch, established through a learning process and having at least a relevant clutch way point for the starting procedure. In case of any recognized change(s), the clutch way point is suitably corrected or otherwise used as is. | 2010-08-12 |
20100204011 | VEHICLE CONTROLLER AND CONTROL METHOD - The invention relates to a controller for a vehicle having installed thereon a drive power source, a transmission, and a torque converter that is equipped with a lockup clutch and is provided between the drive power source and the transmission. The controller includes a detection unit that detects an actual revolution speed of the drive power source, and a control unit that controls the lockup clutch so that a state of the lockup clutch becomes any state from among a disengaged state, an engaged state, and a slip state. When executing a slip control, the control unit compares the actual revolution speed with the target revolution speed, and feedback controls a transmission torque of the lockup clutch on the basis of a comparison result of the actual revolution speed and a target revolution speed so as to cause the actual revolution speed to follow the target revolution speed. | 2010-08-12 |
20100204012 | ABDOMINAL EXERCISER WITH ELECTRONIC COACHING DEVICE - An abdominal exercise apparatus includes a device that instructs and encourages a user. The apparatus comprises a slide member positioned in a channel of a body. The slide member has a user engagement end extending from the channel for engaging a targeted muscle area of the user. A resilient member biases the body and slide in one direction. Handles are attached to the body at opposing locations, and extend away from the body. The instructional device instructs users how to perform multiple phase abdominal exercises and provides motivation. The instructional device comprises a microprocessor, a sound creating mechanism, a visual display, and a user interface. The sound creating mechanism produces prerecorded instructions or motivation. The visual display includes lights to visually instruct the user of the proper amount of time for each phase of an exercise. The user interface allows for a user to select various exercise routines and levels. | 2010-08-12 |
20100204013 | Actual roadway condition simulation system and method - The present invention discloses an actual roadway condition simulation system and method. The system includes a driving recoding device, a computer and a training platform. The computer receives and calculates data filed in the driving recording device and then transmits the data to the training platform, and the training platform produces resistance strength. The method includes: the driving recording device receiving a GPS positing packet signal and accessing data to be filed, and then transmitting the data to the computer; the computer displaying an electronic map and a driving path track; and the training platform producing resistance strength, thereby simulating the variations of the resistance strength of an actual path and achieving the effect of simulating actual roadway condition. | 2010-08-12 |
20100204014 | CORE STABILIZING RUNNING EXERCISE SYSTEM AND APPARATUS - An exercise apparatus in this disclosure includes a doorway mountable runner restraint device. The device has a generally rigid, preferably padded, belly pad that is placed against and in front of a user's pelvis and abdominal area. A pair of cords are attached to the belly pad, each having an opposite end attached to an elastic member. Each of the elastic members is, in turn, attached to an anchor which is removably fastened to a door, a doorway frame, or sandwiched between a closed door and the doorway frame. A user fastens the apparatus in place in a doorway, faces away from the doorway, and places the belly pad against his or her torso directly over the pelvis area, and then runs in a direction away from the doorway. The elastic members resist and restrain the user from substantial movement away from the doorway but stretch to allow forward running movement. | 2010-08-12 |
20100204015 | Interactive system for exercise condition and method thereof - An interactive system for exercise condition and a method thereof are described. In the system and method, a trainer terminal gives an exercise direction to a trainee terminal through a server according to exercise data and physiological data that represent the trainee terminal generated by a measurement equipment, so as to solve the problem existing in the prior art that the trainee might be injured due to the continuous and inappropriate fitness exercise because a fitness trainer has no time to give the exercise direction, thereby achieving the technical efficacy of real-time and long-time continuously giving the appropriate exercise direction to the trainee. | 2010-08-12 |
20100204016 | System and method for editing walking procedure - A system and a method for editing a walking procedure are provided. Various walking parameters of the user are operated by loading a walking mode, so as to obtain walking steps of the user corresponding to each time parameter of the walking mode. Further, the walking procedure is converted to a walking pattern procedure, and the walking pattern procedure is provided to the user for dynamically editing and modifying. Finally the walking procedure is stored. Thus, a problem that a personal walking procedure cannot be provided is solved, thereby providing the personal walking procedure and improving exercise efficiency. | 2010-08-12 |
20100204017 | Adaptive motion exercise device with plural crank assemblies - An exercise device includes a first crank arm assembly and a second crank arm assembly supporting opposite portions of a guide. A first foot pad is coupled to the guide to reciprocate along the guide. A foot pad link has a first end portion pivotably connected to the foot pad and a second end portion pivotably supported about an axis that is movable along one of a plurality of user selectable paths, each of the plurality of user selectable paths having a different length. | 2010-08-12 |
20100204018 | Treadmill Cross Training Conversion - This device comprises two upward extending arms and adjustable mounting brackets that can be attached independently to the handrails of most treadmills and affords users an opportunity to exercise the upper body in an action similar to cross country skiing. | 2010-08-12 |
20100204019 | METHOD AND DEVICE FOR ADJUSTING THE DISTANCE BETWEEN TWO MEMBERS, AT LEAST ONE OF WHICH IS MOBILE, AND SWIMMING HARNESS USING THE SAME - An elastic link for adjusting the distance between two members, at least one of which is mobile, is characterised in that it includes at least two elastic yarns each attached through one of the opposite ends thereof to two points distant from each other of an intermediate portion of a strap located between the extreme portions of the latter, under conditions such that when a tensile force is applied on said strap, the first elastic yarn is stretched first, the second elastic yarn being then stretched based on the magnitude of the applied tensile force. | 2010-08-12 |
20100204020 | Exercise Device - The present invention resides in an exercise device that is lightweight and easy to transport, and is particularly effective in improving neuromuscular/proprioceptive coordination, balance and core strength. The exercise device draws on the well known physical fitness benefits of canoe and kayak paddling, and at the same time is a device that can be used in a gym, home, office, or at any land site desired. The exercise device of the present invention comprises a pole that can be grasped in two hands similar to grasping a canoe or kayak paddle. A yoke is positioned at one end of the pole. A roller is held axially in the yoke. A variable resistance brake controls the ease with which the roller is able to rotate within the yoke. An adjustment means may be positioned on the pole that allows the user of the device to control the variable resistance. | 2010-08-12 |
20100204021 | TORSO EXERCISE MACHINE - A lower torso exercise machine for a user having a frame; a user support structure mounted to the frame, the user support structure including a seat and a pelvic stabilizing pad, the seat being mounted to the frame below and at an angle oblique to the pelvic stabilizing pad; and a footrest attached to the frame in front of the user support structure for pushing against by the user's feet, the seat and the stabilizing pad being adjustably positionable relative to the footrest such that the user can selectively adjust the force of the user's pushing against the footrest to enable the user to push the user's pelvis into the stabilizing pad to a degree that immobilizes the user's pelvis. | 2010-08-12 |
20100204022 | Training apparatus - The present invention is to provide a training apparatus capable of providing the soft and highly elastic muscles of shoulder parts, arm parts, and a rear part without the hardening of the muscles and loads on the body, such as muscle pain and fatigue. The training apparatus | 2010-08-12 |
20100204023 | ADJUSTABLE RESISTANCE EXERCISE DEVICE - A resistance exercise device enables resistance training by using one or more retractable cables that provide resistance to the user when the user pulls on the cable(s). The resistance exercise device provides a retraction force to retract the cable(s), which is independent of a resistance force applied to the cable(s). The resistance exercise device may thus allow adjustment of the resistance force without affecting the retraction force. | 2010-08-12 |
20100204024 | ADJUSTABLE RESISTANCE EXERCISE DEVICE - A resistance exercise device enables resistance training by using one or more retractable cables that provide resistance to the user when the user pulls on the cable(s). The resistance exercise device provides a retraction force to retract the cable(s), which is independent of a resistance force applied to the cable(s). The resistance exercise device may thus allow adjustment of the resistance force without affecting the retraction force. | 2010-08-12 |
20100204025 | ABDOMINAL EXERCISE MACHINE - A sports fitness/rehabilitation machine assists in strengthening the abdominal muscle region and includes a base having a main adjustment assembly, an upper adjustable support pivotally attached to the main adjustment assembly, and a lower adjustable support pivotally attached to said main adjustment assembly. The machine may also include an upper adjustable support arm, handle bars, a back and headrest pad, a leg adjustment member, and a foot rest, or any combination of these additional features. | 2010-08-12 |
20100204026 | WORKOUT BAR - Preferably, the invention is concerned with a unique “w” shaped exercise bar, a short elongated central shaft that easily comes apart, a pair of hand grip portions disposed on either side of the central shaft, and a pair of removable jump rope handles with adjustable color coded-retractable ropes hidden inside the handles. When together, the bar is ergonomically designed to fit the smaller frames of the age demographic it is intended for (children ages 8 and up), allowing them to perform many exercises in the field of musculoskeletal strengthening, musculoskeletal flexibility, and cardiovascular conditioning. When the bar is taken apart and transformed, the individual pieces complete a pair of light weight dumbbells and an adjustable jump rope designed to fit any child's size from 3 ft to 7 ft tall. | 2010-08-12 |
20100204027 | THERAPEUTIC EXERCISE APPARATUSES - Described herein are exercise apparatuses suitably adapted for use by crippled persons for exercising their hips and legs. In one embodiment, an apparatus with a supporting structure and a seat mounted on the supporting structure. A cushion comprising a pad for splaying the knees of a user is mounted on the supporting structure. In another embodiment, there is a docking station suitably adapted for wheelchair users with a supporting structure protruding therefrom. A cushion is mounted on the protrusion for splaying the knees of the user. In yet another embodiment, a semispherical shaped seat is mounted on a supporting structure that can be adjusted to position a user near a handlebar structure with a supporting structure protruding therefrom. A cushion is mounted for splaying the knees of the user. Optionally, the cushions in the example embodiments may further comprise a patella pad. A knee spreader ball detached from the exercise apparatus permits training without the fixed cushion and, in a further form permits transport of a user without tangling the feet of the user. | 2010-08-12 |
20100204028 | System for Changing and Inserting or Placing Tools on a Machine Tool and Tool Magazine for Storing Tools - The present invention relates to a system for changing and inserting or placing tools on a machine tool, comprising a tool magazine for storing a plurality of tools and a handling device for taking the tools out of the tool magazine, wherein according to the invention the tool magazine is formed such that the tools are stored on top of each other on different levels inside the tool magazine, the levels overlapping each other such that compartments for receiving the tools are formed which are each arranged on the levels along a circular arc or a circular arc segment, and the handling device being adapted to take the tools out of the compartments radially inwardly and/or radially outwardly. Furthermore, the present invention relates to a tool magazine of such system and a machine tool in combination with such system. | 2010-08-12 |
20100204029 | DRESSING ROLL MOUNTING DEVICE - A dressing roll mounting device for mounting a dressing roll to a dresser shaft of a grinding wheel dressing unit is provided. The dressing roll mounting device includes a mounting sleeve to be positioned at a free end of the dresser shaft, the outer face of the mounting sleeve being provided with a conical mounting region serving as a centering and pushing-on aid during mounting of the dressing roll to the dresser shaft. The maximum outside diameter of the conical mounting region is smaller than or corresponding to a dressing roll reception diameter of the dresser shaft. | 2010-08-12 |
20100204030 | Collapsed Tubular Carton Erecting Apparatus & Methods - Methods and apparatus ( | 2010-08-12 |
20100204031 | CORE WINDER WITH FORMING UNIT WITH A TOOTHED BELT - A core winder is disclosed for forming tubes from at least one helically wound strip of web material, including: a spindle, about which the strip or strips of web material are wound; a forming unit including a belt entrained about at least two pulleys, at least one of which is motorized. The belt forms a loop about the forming spindle. The belt has a front face provided with a toothing cooperating with one of the pulleys, which is also toothed. | 2010-08-12 |
20100204032 | SEPARATOR FOR SEPARATING AIR AND FROM A DENTAL WASTE WATER MIXTURE - The present invention relates to a separator for separating air and possibly present solids from a mixture of dental waste water, comprising an air-water separator, wherein a mixture supply tube opens into a centrifuge drum, an air discharge duct extends from the centrifuge drum to the mixture supply tube and the centrifuge drum includes an upper drain edge over which a water outlet is guided onto the outside of the centrifuge drum. In accordance with the invention, the separator is characterized in that the mixture supply tube opens onto a central turbine wheel arranged above the centrifuge drum bottom and an impeller of a waste water delivery pump, which communicates with the water outlet, is arranged on an outside of the centrifuge drum in the vicinity of the centrifuge drum bottom. | 2010-08-12 |
20100204033 | ZIRCONIUM DIOXIDE POWDER AND ZIRCONIUM DIOXIDE DISPERSION - Zirconium dioxide powder in the form of aggregated primary particles, having a BET surface area of 30 to 150 m2/g and a Berger whiteness of at least 88%. It is prepared by atomizing a solution which comprises an organic zirconium compound and mixing it with a combustion gas and air and allowing the mixture to burn in a flame into a reaction chamber surrounded by a casing, where the temperature in the reaction chamber and along the side of the wall of the casing facing the reaction chamber is at least 500° C. Dispersion comprising the zirconium dioxide powder. Use of the zirconium dioxide powder and of the dispersion for producing ceramics. | 2010-08-12 |
20100204034 | DIELECTRIC CERAMIC COMPOSITION AND ELECTRONIC COMPONENT - The dielectric ceramic composition comprising a main component including a compound satisfying a compositional formula of (Sr | 2010-08-12 |
20100204035 | HIGH STRENGTH CLAY BLEND FOR SANITARY WARE - A blend of ball clays for use as the ball clay component of a slip to produce a ceramic sanitary ware item by a slip casting process. The clay blend including 20-50 percent of a fine-grained ball clay with a low carbon content and 45-55 percent of its particles having a size less than 0.5 microns and about 85-95 percent of the particles less than about 20 microns. | 2010-08-12 |
20100204036 | NOx PURIFYING CATALYST - Disclosed is a NOx purifying catalyst which is capable of removing NOx sufficiently efficiently even during operations at low temperatures such as operations in diesel cars. Specifically disclosed is a NOx purifying catalyst for processing NOx in an exhaust gas by performing lean/rich control of air-fuel ratio of the exhaust gas. This NOx purifying catalyst comprises at least a first catalyst layer containing a β zeolite containing iron element and a second catalyst layer containing a noble metal, a cerium oxide material and a specific zirconium oxide material. The second catalyst layer and the first catalyst layer are sequentially arranged on a carrier in such a manner that the first catalyst layer forms the uppermost layer. | 2010-08-12 |
20100204037 | SELF-CLEANING SURFACE COATING (PHOTOCATALYSIS) - A self-cleaning surface coating is easy and inexpensive to produce because it has only a simple titanium dioxide layer. | 2010-08-12 |
20100204038 | Catalysts based on metal complexes for the synthesis of optically active chrysanthemic acid - Catalysts are described based on metal complexes derived from optically active s compounds, chosen from the classes consisting of bisoxazolines and salicylaldimines supported on an organic or inorganic matrix and employed in particular for the synthesis of optically active chrysanthemic acid. | 2010-08-12 |
20100204039 | Exhaust Gas-Purifying Catalyst - The exhaust gas-purifying catalyst includes at least one of a first composite oxide represented by a formula A(Al | 2010-08-12 |
20100204040 | VISIBLE-LIGHT-RESPONSIVE PHOTOCATALYST POWDER, METHOD OF MANUFACTURING THE SAME, AND VISIBLE-LIGHT-RESPONSIVE PHOTOCATALYTIC MATERIAL, PHOTOCATALYTIC COATING MATERIAL AND PHOTOCATALYTIC PRODUCT EACH USING THE SAME - A visible-light-responsive photocatalyst powder includes a tungsten oxide powder. When the tungsten oxide powder is measured by X-ray diffractometry, (1) among intensity ratios of a peak A (2θ=22.8 to 23.4°), a peak B (2θ=23.4 to 23.8°), a peak C (2θ=24.0 to 24.25°), and a peak D (2θ=24.25 to 24.5°), an A/D ratio and a B/D ratio each fall within a range of 0.5 to 2.0, and a C/D ratio falls within a range of 0.04 to 2.5, (2) an intensity ratio (E/F) of a peak E (2θ=33.85 to 34.05°) to a peak F (2θ=34.05 to 34.25°) falls within a range of 0.1 to 2.0, and (3) an intensity ratio (G/H) of a peak G (2θ=49.1 to 49.7°) to a peak H (2θ=49.7 to 50.3°) falls within a range of 0.04 to 2.0, and the tungsten oxide powder has a BET specific surface area in a range of 1.5 to 820 m | 2010-08-12 |
20100204041 | VISIBLE-LIGHT-RESPONSIVE PHOTOCATALYST POWDER, AND VISIBLE-LIGHT-RESPONSIVE PHOTOCATALYTIC MATERIAL, PHOTOCATALYTIC COATING MATERIAL AND PHOTOCATALYTIC PRODUCT EACH USING THE SAME - A visible-light-responsive photocatalyst powder includes a tungsten oxide powder. The tungsten oxide powder has color whose a* is −5 or less, b* is −5 or more, and L* is 50 or more when the color of the powder is expressed by an L*a*b* color system. Further, the tungsten oxide powder has a BET specific surface area in a range of 11 to 820 m | 2010-08-12 |
20100204042 | PREMIXTURE FOR PREPARING AN ABSORBENT FOR REMOVING ACIDIC GASES FROM FLUID STREAMS - A premix is described for producing an absorption medium for removing acid gases from fluid streams. The premix comprises at least one alkanolamine, piperazine and water, the premix having a total amine content of more than 65% by weight, the molar ratio of water to piperazine in the premix being 1.6 to 4.8. The premix is characterized by a low solidification point. It is diluted with water and/or alkanolamine to give the ready-to-use absorption medium. | 2010-08-12 |
20100204043 | ADSORBENT FOR SELECTIVE ADSORPTION OF CARBON MONOXIDE AND PROCESS FOR PREPARATION THEREOF - The present invention relates to an adsorbent for separating carbon monoxide from a gas mixture including hydrogen gas and a method of preparing the same. The adsorbent for selectively separating monoxide includes a solid material, which is a solid support impregnated and dispersed with a cuprous salt by bringing the solid support into contact with a cuprous salt solution stabilized by dissolving a cuprous salt or a cuprous salt mixture in a solvent. The adsorbent is advantageous in that the selectivity for carbon monoxide is improved, so that the amount of carbon monoxide included in the gas mixture is decreased to infinitesimal quantities, thereby producing high-purity hydrogen products. | 2010-08-12 |
20100204044 | Carrier and method of producing the same - The method of producing a carrier of the invention includes a step of kneading the starting carrier components, solid binding agent, liquid binding agent and diluted nitric acid water. The starting carrier components comprise aluminum hydroxide, pseudoboehmite, γ-alumina, powdery silica gel, powdery natural silica and zeolite. The solid binding agent comprises a powder of α-starch (rice), α-starch (potato), α-starch (tapioca), funori (glue plant), crystalline cellulose and powdery cellulose. The liquid binding agent comprises colloidal alumina, colloidal silica and polyvinyl alcohol. As a de-firing agent, further, there are used wood powder, charcoal powder, rice flour, wheat flour, barley flour, buck wheat flour and corn. The carrier has a pore volume in a range of 0.52 to 0.84 cc/g and a side crushing strength in a range of 2.2 to 11.0 kgf/particle. | 2010-08-12 |
20100204045 | Systemicity Enhancers - A copolymer obtainable by polymerization of
| 2010-08-12 |
20100204046 | Processes for the Control of Undesired Vegetation - Improved agricultural processes for the controlled cultivation of crops are disclosed. In one aspect, crops of different types, namely that is to say crops grown from seeds, plants or cultivars having resistance to two (or more) different classes of herbicides, are treated to control undesired vegetative growth using a single class of herbicides. | 2010-08-12 |
20100204047 | Alkoxylated asymmetric alkylamine surfactants as adjuvants - The present invention generally relates to a herbicidal formulation that comprises at least one phenoxy acid herbicide or an agriculturally acceptable salt or derivative thereof, and a surfactant adjuvant, wherein said surfactant adjuvant comprises at least one alkoxylated asymmetric alkylamine surfactant having the formula (I) wherein R1 is a straight or branched chain, saturated or unsaturated hydrocarbyl group having from 8 to 24 carbon atoms; R2 is a C1-C4 alkyl group or a benzyl group; A is an alkylene group containing from 2-4 carbon atoms; x is 1-30; and y is 0-10; or a quaternised derivative of (I) having the formula (II) wherein R1 is a straight or branched chain, saturated or unsaturated hydrocarbyl group having from 8 to 24 carbon atoms; R2 is a C1-C4 alkyl group or a benzyl group; A is an alkylene group containing from 2-4 carbon atoms; x is 1-30; y is 0-10; R3 is a C1-C4 alkyl group; and Y | 2010-08-12 |
20100204048 | METHOD FOR THE IMPROVED USE OF THE PRODUCTION POTENTIAL OF TRANSGENIC PLANTS - The invention relates to a method for improving the utilization of the production potential of transgenic plants by treating the plant with an effective amount of at least one compound of the formula (I) | 2010-08-12 |
20100204049 | OXIDE SUPERCONDUCTING FILM AND METHOD OF PREPARING THE SAME - The present invention relates to a method of preparing an oxide superconducting film, the method includes reacting a metal acetate containing metal M selected from the group consisting of lanthanum, neodymium and samarium with fluorocarboxylic acid having not less than three carbon atoms, reacting barium acetate with fluorocarboxylic acid having two carbon atoms, reacting copper acetate with fluorocarboxylic acid having not less than two carbon atoms, respectively, followed by refining reaction products, dissolving the reaction products in methanol such that a molar ratio of the metal M, barium and copper is 1:2:3 to prepare a coating solution, and coating a substrate with the coating solution to form a gel film, followed by calcining and firing the gel film to prepare an oxide superconducting film. | 2010-08-12 |
20100204050 | TARGET PREPARATION FOR PARALLEL SEQUENCING OF COMPLEX GENOMES - The present invention provides a method for the isolation and analysis of a target nucleic acid, the target nucleic acid being present in a sample of genomic DNA, comprising the steps of a) fragmentation of the genomic DNA, b) hybridization of the genomic DNA on a nucleic acid solid support, the solid support comprising a plurality of oligonucleotide probes, the probes being characterized in that each probe is at least partially complementary to the sequence of the target nucleic acid or its complement, under hybridization conditions, characterized in that the plurality of probes hybridizes to fragments of the target nucleic acid but does not hybridize to other nucleic acids which are present in the sample, c) stripping off the target molecules hybridized to the nucleic acid array, d) overlap extension synthesis in order to generate double stranded overlap extension synthesis product, e) fragment polishing, and f) adaptor ligation. | 2010-08-12 |
20100204051 | Hereditary Hemochromatosis Gene - The invention relates generally to the gene, and mutations thereto, that are responsible for the disease hereditary hemochromatosis (HH). More particularly, the invention relates to the identification, isolation, and cloning of the DNA sequence corresponding to the normal and mutant HH genes, as well as the characterization of their transcripts and gene products. The invention also related to methods and the like for screening for HH homozygotes and further relates to HH diagnosis, prenatal screening and diagnosis, and therapies of HH disease, including gene therapeutics, protein and antibody based therapeutics, and small molecule therapeutics. | 2010-08-12 |
20100204052 | Protein scaffolds and uses thereof - The present invention provides thrombospondin, thyroglobulin and trfoil/PD monomer domains and multimers comprising the monomer domains are provided. Methods, compositions, libraries and cells that express one or more library member, along with kits and integrated systems, are also included in the present invention. | 2010-08-12 |
20100204053 | ASSAYS FOR THE IDENTIFICATION OF COMPOUNDS THAT MODULATE BONE FORMATION AND MINERALIZATION - This invention demonstrates that KRC molecules have multiple important functions as modulating agents in regulating a wide variety of cellular processes including bone formation and mineralization. TGF-β signaling in osteoblasts promotes the formation of a multimeric complex between KRC, Runx2, Smad3, and the E3 ubiquitin ligase, WWP1 which inhibits Runx2 function due to the ability of WWP1 to promote Runx2 polyubiquitination and proteasome-dependent degradation. Furthermore, KRC and WWP1 form a complex with RSK2 which inhibits RS K2 function due to the ability of WWP1 to promote RSK2 ubiquitination. Methods for identifying modulators of KRC activity are provided. Methods for modulating an immune response, bone formation and mineralization and KRC-associated disorders using agents that modulate KRC expression and/or activity are also provided. | 2010-08-12 |
20100204054 | METHODS FOR IDENTIFYING INHIBITORS OF BOTULINUM NEUROTOXINS - A system and method for identifying a botulinum neurotoxin inhibitor employing a botulinum neurotoxin substrate complex having a peptide substrate, preferably SNAP-25, a reporter domain on one side of said peptide substrate and an immobilization domain on the opposite side of said peptide substrate. The botulinum neurotoxin inhibitor is identified by its ability to decrease the relative amount of cleaved complex, detected through measuring a decrease in complex bound to a solid support. The method of the present invention also utilizes novel cells that express a botulinum neurotoxin substrate complex. The methods of the present invention are adapted for cell based screening to monitor the catalytic activity of a BoNT in living cells and to identify molecules that inhibit the catalytic activity of a BoNT in living cells. Also provided are novel stable cell lines that express the botulinum toxin substrate complex and viral vectors capable of efficiently expressing an active light chain of the BoNT within mammalian cells. | 2010-08-12 |
20100204055 | AUTOANTIBODY DETECTION SYSTEMS AND METHODS - Autoantibodies in biological samples such as serum can result from changes to biomolecules (e.g., proteins, polysaccharides, and lipids) that are associated with disease. Such autoantibodies are useful biomarkers because they frequently appear early in disease and are readily accessible, particularly in biological fluids such as blood and serum. CT antigens are particularly useful for detecting autoantibodies correlated with cancer. Numerous population-based profiles for pluralities of different autoantibody species, at least some of which are specifically reactive with CT antigens, allow for simultaneous assessment of multiple disease-associated analytes is a single test, which can be more effective in diagnostics and drug development than individual profiles. The instant invention provides autoantibody detection array devices that include a plurality of independently selected autoantibody-reactive reagent species, such as full-length CT antigens or the antigenic portions thereof, disposed on a substrate. Such arrays can be used to screen biological samples taken from patients or other subjects for diagnostic, drug development, and other applications. | 2010-08-12 |
20100204056 | QUALITY-CONTROL AND ALIGNMENT ELEMENT FOR ASSAY SUBSTRATES - A method for fabricating and assessing the quality of printing on substrates used for chemical or biological array testing, and method for ascertaining relative consistency of the deposit reproducibility is described. Generally, the method involves: providing a substrate, providing a solution mixture of a capture moiety and a colorant; depositing an amount of said solution mixture onto said substrate, monitoring the substrate such that the visible indicator colorant manifests in a co-extensive fashion as with the capture moiety on the substrate. In another aspect, the invention relates to a sensor or assay device comprising a physical complex of a number of capture agents and an amount of colorants adhere to least a part of a surface of a substrate. | 2010-08-12 |
20100204057 | SUBSTRATE FOR MICROARRAY, METHOD OF MANUFACTURING MICROARRAY USING THE SAME AND METHOD OF OBTAINING LIGHT DATA FROM MICROARRAY - Provided is a substrate that is used to produce a microarray, wherein the substrate includes; a fiducial mark disposed on the substrate, and a probe immobilization region disposed on the substrate, wherein a surface of the first fiducial mark is a hydrophobic and a probe immobilization compound is immobilized on the probe immobilization region. | 2010-08-12 |
20100204058 | Profiling for Determination of Response to Treatment for Inflammatory Disease - The present invention relates to compositions and methods for treating, characterizing, and diagnosing autoimmune diseases or other inflammatory diseases. In particular, the present invention provides gene expression profiles as well as novel TKI Responsive Signature(s) useful for the diagnosis, characterization, prognosis and treatment of autoimmune disease or other inflammatory diseases. | 2010-08-12 |
20100204059 | CDR-Anchored Amplification Method - A method of obtaining nucleic acid encoding a plurality of antibodies is provided. In certain embodiments, the method comprises obtaining from an immunized animal nucleic acid encoding the amino acid sequence of the heavy and light chains of a second antibody that binds to the antigen as a first antibody and differs in amino acid sequence to the first antibody, wherein the obtaining is done by amplification using: i. a first primer pair that includes oligonucleotides are complementary to CDR-encoding regions first antibody. | 2010-08-12 |
20100204060 | HYPOXIA-INDUCIBLE PROTEIN 2 (HIG 2), A DIAGNOSTIC MARKER FOR CLEAR CELL RENAL CELL CARCINOMA - The present invention provides a method for inhibiting growth of a cancer cell, particularly a renal cell carcinoma, by contacting the cell with a composition composed of an HIG2 siRNA or HIG2 antibody. Methods of diagnosing renal cell cancer are also provided within the present invention. | 2010-08-12 |
20100204061 | Method and system for determining whether a drug will be effective on a patient with a disease - A process of determining whether a patient with a disease or disorder will be responsive to a drug, used to treat the disease or disorder, including obtaining a test spectrum produced by a mass spectrometer from a serum produced from the patient. The test spectrum may be processed to determine a relation to a group of class labeled spectra produced from respective serum from other patients having the or similar clinical stage same disease or disorder and known to have responded or not responded to the drug. Based on the relation of the test spectrum to the group of class labeled spectra, a determination may be made as to whether the patient will be responsive to the drug. | 2010-08-12 |
20100204062 | CALIBRATION METHODS FOR MULTIPLEXED SENSOR ARRAYS - The present invention relates to the calibration of devices using a secondary binding agent or reference material. In one embodiment, the present invention provides a method of calibrating a nanosensor by providing a nanosensor comprising an analyte binder attached to a reference binder, extracting a calibration curve from binding a reference material to the reference binder, and calibrating the nanosensor by using the calibration curve to correct for device variation. | 2010-08-12 |
20100204063 | DNA CHIP PACKAGE AND METHOD FOR FABRICATING THE SAME - A DNA chip package includes; a base substrate, a photoresist layer disposed on the base substrate, at least one DNA chip mounting groove disposed in the photoresist layer and exposing the base substrate therethrough, and at least one DNA chip mounted in the at least one DNA chip mounting groove. | 2010-08-12 |
20100204064 | INTEGRATED BIO-CHIP AND METHOD OF FABRICATING THE INTEGRATED BIO-CHIP - An integrated bio-chip includes; a sample detection portion including at least one light receiving device which detects fluorescent light emitted from at least one sample, a light transfer portion disposed on a light incident surface of the sample detection portion, and which includes at least one excitation light absorbing waveguide which absorbs an excitation light and transmits the fluorescent light emitted from the at least one sample, and a sample reaction portion disposed adjacent to an incident end of the at least one excitation light absorbing waveguide, and including at least one reaction region on which the at least one sample is attached, wherein the sample detection portion, the light transfer portion, and the sample reaction portion are integrally coupled to each other as a single component. | 2010-08-12 |
20100204065 | MICROARRAY USING LAMINAR FLOW AND METHOD OF PREPARING THE SAME - A microarray including hydrogel and a plurality of probes which are immobilized in discrete regions of the hydrogel, and a method of preparing the same are provided. When using the microarray and method, a solid substrate is not required and many biomolecules can be immobilized in a small volume, thereby obtaining high sensitivity. Since gel can be cut to obtain many pieces, many microarrays can be prepared at once. | 2010-08-12 |
20100204066 | WATER ABSORBING POLYMERS FOR TREATMENT OF BRINES AND WATER-BASED DRILLING FLUIDS - A method for removing water from a wellbore fluid is disclosed. The method may include the steps of contacting a wellbore fluid with a water absorbing polymer, where the wellbore fluid includes an aqueous fluid, allowing the water absorbing polymer to interact with the wellbore fluid for a sufficient period of time so that the water absorbing polymer absorbs at least a portion of water in the aqueous fluid, and separating the water absorbing polymer containing the absorbed water from the wellbore fluid. | 2010-08-12 |
20100204067 | Drilling Fluid Additive and Method for Improving Lubricity or Increasing Rate of Penetration in a Drilling Operation - The present invention relates to a drilling fluid additive for improving lubricity or rate of penetration (ROP) in a drilling operation, such as an oil and gas drilling operation. The additive comprises particles of wax or waxy substance, or a mixture of two or more types of said particles having distinct properties, such as particle size, type of wax or waxy substance, melt point, solubility, dissolution rate, hardness, shape, blocking ability, or a combination thereof. In certain embodiments, the additive is environmentally friendly and biodegradable. The invention also relates to a drilling fluid comprising the drilling fluid additive of the invention. A method of improving lubricity or increasing ROP in a drilling operation is also provided, as well as a use of particles of wax or waxy substance or mixture thereof as a drilling fluid additive for improving lubricity or increasing ROP in a drilling operation. | 2010-08-12 |
20100204068 | Methods for controlling depolymerization of polymer compositions - A method of controlling or arresting the rate of depolymerization of a polymer composition during a biocide treatment by controlling the pH of the composition, and use of such methods in oilfield applications. | 2010-08-12 |
20100204069 | METHOD OF STIMULATING SUBTERRANEAN FORMATION USING LOW pH FLUID - Hydraulic fracturing is conducted by use of a well treatment fluid which contains a guar gum derivative as viscosifying or gelling polymer, an organic zirconate complex of a zirconium metal and an alkanol amine as crosslinking agent and a hydroxylated glycine as crosslinking delaying agent. The fluid is characterized by a low pH, generally greater than or equal to 3.0 and less than or equal to 5.0. | 2010-08-12 |
20100204070 | LOW DENSITY COMPOSITE PROPPING AGENTS - Composite propping agents of low density and of high mechanical strength are based on a thermoplastic polymer matrix, in particular having low compressive deformation at high temperatures are especially useful in the field of well fracturing for the recovery of sludges, liquids and gases present in underground reservoirs, and in particular in the field of the extraction of hydrocarbons, such as crude oil or natural gas. | 2010-08-12 |
20100204071 | AQUEOUS PARTICULATE SLURRY COMPOSITIONS AND METHODS OF MAKING SAME - A sand slurry composition and a method for making sand slurries are disclosed. The sand slurry composition is comprised of sand, an aqueous liquid and a chemical compound that renders the surface sand of hydrophobic. The method is comprised of rendering sand surface hydrophobic during or before making the slurry. This method and composition can find many applications in different industries, especially in various oil field applications. | 2010-08-12 |
20100204072 | Nanoparticle graphite-based minimum quantity lubrication method and composition - A lubricant composition is disclosed that includes (a) a machining oil and (b) an exfoliated graphite nanoparticle (EGN) material stably dispersed in the machining oil. The lubricant composition is a stable suspension and is suitable for use as a liquid lubricant in a Minimum Quantity Lubrication (MQL) process. In the MQL process, the lubricant composition is applied/transferred to a worksite in the form of a mist. The presence of the EGN material in the lubricant composition provides high-temperature stability and lubricity under MQL conditions. A very small amount is transferred especially at high cutting speeds where the mist of the machining oil evaporates, but the EGN material remains on the surface to provide lubricity. Any operation involving machining can benefit from this lubricant composition. The method provides important benefits of reducing chipping on cutting tools and providing the additional lubricity especially when the cutting become very hot and thus extending tool life. | 2010-08-12 |
20100204073 | ENGINE WEAR PROTECTION IN ENGINES OPERATED USING ETHANOL-BASED FUEL - Lubricant formulations and methods for producing lubricant formulations are described that provide improved wear protection in engines operated using ethanol-based fuels. The improved wear protection may be provided by an increased amount of overbased calcium detergent present in the formulation. | 2010-08-12 |
20100204074 | Compounds That Are Liquid At Ambient Temperature - Disclosed are ionic liquids that have a low melting point. Said liquids are provided in the form of compounds that are selected among the group comprising tetraalkyl ammonium salts, benzyl trialkyl ammonium salts, tetraalkyl phosphonium salts, and benzyl trialkyl phosphonium salts, provided that at last two alkyl groups represent aliphatic radicals with chain lengths ranging from 8 to 10 C atoms, and provided that not all alkyl radicals are identical. | 2010-08-12 |
20100204075 | Environmentally compatible hydraulic fluid - Environmentally safe and compatible fluids that are useful as lubricants, and especially as hydraulic fluids, in mobile machinery are formulated to be non-contaminating when accidentally contacted with surrounding vegetation, and removable from vegetation by simply washing the vegetation with tap water. The fluids of the invention are polyalkylene glycol-based and having an ethylene oxide to propylene oxide ratio of from about 68:32 to about 78:22. | 2010-08-12 |
20100204076 | GELLED NAIL POLISH REMOVER - A gelled nail polish remover includes of a thickening agent of approximately 1.0%-5.0% by weight, low volatility organic solvents of approximately 85%-99% by weight, a skin conditioning agent of approximately 0.1%-5.0% by weight, and an antioxidant of approximate 0.15%-0.3% by weight, which are mixed to form a gel for removing nail polish and featuring low toxin, low volatility, low flammability, and almost no odor smell. | 2010-08-12 |
20100204077 | Method for Cleaning Processing Equipment, Such As Filters - A method for cleaning process apparatus used for production of liquids, especially for cleaning filters, for example membrane filters. The apparatus is contacted with a solution of peroxydisulphate. It is especially preferred that the cleaning process is carried out at a temperature between 15 and 95° C. | 2010-08-12 |
20100204078 | METHOD FOR FOAMING A CLEANING COMPOSITION - A method for foaming a cleaning composition is provided. The method includes mixing a cleaning composition and air in a mechanical foaming head to generate a foam without the use of a non-air containing propellant. The cleaning composition includes about 0.01 wt. % to about 10 wt. % total amount of surfactant, at least about 80 wt. % water and a glycol ether solvent. The glycol ether solvent includes one or more glycol ethers, each having a HLB value of at least about 6.9 and an OHLB value of between about 12 and about 20. The weight ratio of the glycol ether solvent to the total amount of surfactant is at least about 1:100. | 2010-08-12 |
20100204079 | Cleaning Enzymes and Malodor Prevention - The present invention provides compositions comprising an acyltransferase and an alcohol substrate for the acyl-transferase. In some particularly preferred embodiments, the composition finds use in production of a fragrant ester. In some other embodiments, the composition finds use in laundry detergents to clean stains that contain at least one triglyceride. In some further embodiments, the compositions are used to produce compounds with cleaning properties (e.g., a surfactant ester). | 2010-08-12 |
20100204080 | Novel Cellulases and Their Uses - The present invention provides novel cellulase fusion proteins, preparations of cellulase fusion proteins and compositions of cellulase fusion proteins. The present invention further provides cellulase expression vectors, host cells expressing cellulase and methods for preparing such vectors and cells. Uses of cellulases, cellulase preparations and cellulase compositions in the textile, detergent, pulp and paper industries are also provided. | 2010-08-12 |
20100204081 | RHEOLOGY MODIFIER FOR AQUEOUS SURFACTANT-BASED FORMULATIONS - The present invention relates to aqueous formulations useful in useful in personal care, oral care, household and institutional applications which contain polymers comprised of water soluble synthetic backbone with covalently connected hydrophobic ends can deliver ‘salt-like’ rheology to surfactant formulations containing surfactant concentrations at which thickening by salt is not effective. | 2010-08-12 |
20100204082 | Alkaline compositions and methods of producing same - Compositions, such as alkali builder compositions for the laundry industry, are provided and include water, an alkali metal hydroxide component, a chelating component and a hydroxyethyliminodiacetic acid (HEIDA) component. Methods for producing such compositions are also disclosed. | 2010-08-12 |
20100204083 | PROCESS FOR THE PREPARATION OF ETHYLGERANONITRILE - The present invention relates to a method of producing ethylgeranonitrile through reaction of ethylheptenone with a deprotonated nitrile and, if appropriate, subsequent saponification and decarboxylation. Moreover, the invention relates to mixtures comprising 3,7-dimethyl-2,6-nonadienenitrile and at least one compound selected from the group of compounds 3,7-dimethyl-3,6-nonadienenitrile and 3-methylene-7-methyl-6-nonenenitrile, and to fragrance compositions comprising these. | 2010-08-12 |
20100204084 | Cyclohexene Derivatives and Their Use as Odorants - The present invention relates to a process for the production of formyl cyclohexene derivatives which are suitable as odorants as such or as intermediates for the preparation of further odorants. In particular the present invention relates to a domino-methylenation-Diels-Alder reaction of α,β-unsaturated aldehydes using formaldehyde in the presence of 1,3-butadienes | 2010-08-12 |
20100204085 | STRUCTURE-BASED DESIGN OF PEPTIDE INHIBITORS OF AMYLOID FIBRILLATION - The invention provides methods for designing peptides that inhibit aggregation in target polypeptides. The candidate inhibitory peptidic compounds have an oligomeric sequence that forms energetically-favorable interactions with the amino acid sequence of the steric zipper region of the target protein, and also possess a zipper-disrupting feature that disrupt the peptide stacking at the steric zipper region. This method can be used to obtain inhibitory peptides to disrupt fibril formation involving any protein for which a steric zipper sequence can be identified. The invention also provides inhibitory peptidic compounds, which can be used in pharmaceutical compositions and methods for treating polypeptide aggregation-associated diseases or conditions. | 2010-08-12 |
20100204086 | BONE MORPHOGENIC PROTEINS (BMP), BMP RECEPTORS AND BMP BINDING PROTEINS AND THEIR USE IN THE DIAGNOSIS AND TREATMENT OF GLAUCOMA - The present invention provides methods and kits for diagnosing and treating glaucoma. | 2010-08-12 |
20100204087 | TRIBONECTINS - The invention features a tribonectin and a method of tribosupplementation carried out by administering tribonectins directly to an injured or arthritic joint. | 2010-08-12 |
20100204088 | Cyclic Peptide Antitumor Agents - Cyclic peptide compounds and derivatives thereof having antitumor activity as shown by treatment of human melanoma, pancreatic, breast, prostate cancer cells. | 2010-08-12 |
20100204089 | PHOSPHORYLATED PYRONE ANALOGS AND METHODS - The invention relates to phosphorylated polyphenols, phosphorylated flavonoids, and phosphorylated pyrone analogs. Methods and compositions for the modulation of side effects of substances using such phosphorylated compounds are described. Methods and compositions are described for the modulation of blood-tissue barrier (BTB) transporter activity to increase the efflux of drugs and other compounds out of a physiological compartment and into an external environment. In particular, the methods and compositions disclosed herein provide lowered side effects when phosphorylated pyrone analogs are coadministered with therapeutic agents. | 2010-08-12 |
20100204090 | USE OF A PEPTIDE AS A THERAPEUTIC AGENT - The present invention is directed to the use of the peptide compound Cyclo(-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg) as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Cyclo(-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg) optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent. | 2010-08-12 |
20100204091 | SIVA Ubiquitination and/or Degradation-Related Activity and Modulators Thereof - The present invention relates to the ubiquitination and/or degradation-related activity of a SIVA polypeptide and to agents capable of modulating said activity. | 2010-08-12 |
20100204092 | Activin-actrii antagonists and uses for increasing red blood cell levels - In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans. | 2010-08-12 |
20100204093 | USE OF HEAT SHOCK ACTIVATORS FOR TISSUE REGENERATION - The present invention generally provides therapeutic compositions and methods for treating a disease, disorder, or injury characterized by a deficiency in cell number. The method involves inducing a heat shock response in tissue or organ effected by disease and recruiting stem cells to repair or regenerate the disease-effected tissue. | 2010-08-12 |
20100204094 | DIURETIC AND NATRIURETIC POLYPEPTIDES - This document provides diuretic and natriuretic polypeptides. For example, this document provides polypeptides having diuretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have diuretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing diuretic and/or natriuretic activities within a mammal. | 2010-08-12 |
20100204095 | Genetically Modified TFPI And Method Of Making The Same - The present invention provides long half life genetically modified TFPI sequences (LTFPI) for anticoagulation. On the genetically modified TFPI sequence, the lysine at the carboxy-terminal sites 241, 254, 260 and 261 are replaced by alanin and the amino acid asparagine at glycosylation sites 117, 167, 228 and the amino acids serine and threonine at glycosylation sites 174 and 175 are substitutionally mutated. The present invention also provides methods of making the LTFPI through high efficient LTFPI expression from yeast production system. | 2010-08-12 |
20100204096 | TREATMENT OF INFLAMMATION, DEMYELINATION AND NEURONAL/AXONAL LOSS - The invention relates to compositions and methods for treating or preventing inflammation in a mammal comprising mucosal administration of an effective amount of an E-selectin polypeptide. Such compositions and methods are useful for treating or preventing a variety of conditions and diseases, including, for example, stroke, vascular dementia and autoimmune or inflammatory demyelinating diseases such as multiple sclerosis. | 2010-08-12 |
20100204097 | THERAPEUTIC METHODS USING A THYMUS PEPTIDE - A method for treating or preventing a disease involving a cell having a T1/ST2 receptor, including administering to subject in need thereof a therapeutically effective amount of a thymic peptide, is provided. Also provided is a method for inhibiting the pathological effects of activated monocytes in a subject in need thereof including treating the monocytes with an effective amount of the thymic peptide. | 2010-08-12 |
20100204098 | PEPTIDES WITH ANTIFUNGAL ACTIVITY - The present invention relates to antifungal and/or antibacterial peptides, especially antifungal peptides obtained from insect species, particularly lepidopterans. The present invention also provides methods of using these antifungal peptides to treat or prevent fungal growth for a variety of purposes such as; protecting plants from fungal infections, treating fungal infections of animals, especially humans, and prevention of food spoilage. | 2010-08-12 |
20100204099 | TREATMENT OF TYPE 2 DIABETES, METABOLIC SYNDROME, MYOCARDIAL INJURY AND NEURODEGENERATION WITH HUMANIN AND ANALOGS THEREOF - Provided are methods of using humanin and humanin analogs to treat a mammal exhibiting or at risk for insulin resistance, increase insulin sensitivity in a mammal exhibiting or at risk for insulin resistance, treat type-2 diabetes mellitus, metabolic syndrome, and neurodegeneration, treat and prevent myocardial injury, and determine longevity. | 2010-08-12 |
20100204100 | BIOLOGICAL AGENTS ACTIVE IN CENTRAL NERVOUS SYSTEM - Cell-permeant fusion peptides Tat-PDZ can dose-dependently reduce the threshold for anesthesia. PDZ domain-mediated protein interactions at synapses in the central nervous system play an important role in the molecular mechanisms of anesthesia. Moreover, Tat-PDZ cell-permeant fusion peptides are delivered intracellularly into neurons in the central nervous system subsequent to intraperitoneally injection. By in vitro and in vivo binding assays, we found that the Tat-PDZ dose-dependently inhibited the interactions between NMDARs and PSD-95. Furthermore, behavior testing showed that animals given Tat-PDZ exhibited significantly reduced established inflammatory pain behaviors compared to vehicle-treated group. Our results indicate that by disrupting NMDAR/PSD-95 protein interactions, the Tat-PDZ cell-permeable fusion peptides provide a new approach for inflammatory pain therapy. | 2010-08-12 |
20100204101 | METHOD AND PRODUCT FOR TREATMENT AND/OR PREVENTION OF COMPLICATIONS OF PREMATURITY - The present invention relates to a composition comprising Insulin Growth Factor I (IGF-I) or an analog thereof in combination with Insulin Growth Factor Binding Protein (IGFBP) or an analog thereof, said combination having a molar ratio of IGF-I to IGFBP being lower than equimolar, preferably in the range from 1:20 to 1:3.33, for use in the treatment of a patient suffering from complications of preterm birth, very preterm birth and/or extremely preterm birth, as well as a method for treating a patient suffering from complications of preterm birth, very preterm birth and/or extremely preterm birth. | 2010-08-12 |
20100204102 | HYBRID GEL COMPRISING CHEMICALLY CROSSLINKED HYALURONIC ACID DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME - The present invention provides a composition comprising a hyaluronic acid derivative having a crosslinking group(s) and a hydrophilic polysaccharide derivative having a hydrophobic group(s), wherein the hyaluronic acid derivative having a crosslinking group(s) is prepared by crosslinkage formation reaction in hyaluronic acid or a derivative thereof having a crosslinkable group(s) in the presence of the hydrophilic polysaccharide derivative wherein the hydrophilic polysaccharide derivative may have a crosslinkable group(s). | 2010-08-12 |
20100204103 | HELICAL SYNTHETIC PEPTIDES THAT STIMULATE CELLULAR CHOLESTEROL EFFLUX - The present invention provides peptides comprising at least one amphipathic alpha helix and having a cholesterol mediating activity and an ABCA stabilization activity. The invention further provides methods of using such peptides. | 2010-08-12 |
20100204104 | FUSION PROTEINS CONTAINING TWO TGF-BETA BINDING DOMAINS OF TGF-BETA TYPE II RECEPTOR - The disclosure provides fusion proteins that contain two TGF-β binding domains of TGF-β type II receptor joined to each other by a linker. For example, the C terminus of the first TGF-β binding domain is joined by a short peptide linker (e.g., a 9-glycine linker) to the N terminus of the second TGF-β binding domain. Despite the proximity of the C terminus of the first domain to N terminus of the second domain, such a fusion protein effectively neutralizes TGF-β, in some cases, similarly to anti-TGF-β antibodies. | 2010-08-12 |