30th week of 2011 patent applcation highlights part 47 |
Patent application number | Title | Published |
20110184151 | SINGLE DOMAIN ANTIBODIES DIRECTED AGAINST EPIDERMAL GROWTH FACTOR RECEPTOR AND USES THEREFOR - The present invention relates to polypeptides derived from single domain heavy chain antibodies directed to Epidermal Growth Factor Receptor. It further relates to single domain antibodies that are Camelidae VHHs. It further relates to methods of administering said polypeptides orally, sublingually, topically, intravenously, subcutaneously, nasally, vaginally, rectally or by inhalation. It further relates to protocols for screening for agents that modulate the Epidermal Growth Factor Receptor, and the agents resulting from said screening. The invention further a method for delivering therapeutic molecules to the interior of cells. | 2011-07-28 |
20110184152 | Biological Products - A multivalent antibody fusion protein which comprises an immunoglobulin moiety, for example a Fab or Fab′ fragment, with a first specificity for an antigen of interest, and further comprises two single domain antibodies (dAb) with specificity for a second antigen of interest, wherein the two single domain antibodies are linked by a disulfide bond. There is also provided particular dual specificity antibody fusion proteins comprising a Fab or Fab′ fragment and one or more single domain antibodies which may be stabilised by a disulfide bond therebetween. | 2011-07-28 |
20110184153 | MODIFIED GHERLIN PEPTIDES - The present invention provides a novel peptide-type compound which induces secretion of growth hormone and which has the activity of increasing the intracellular calcium ion concentration, wherein at least one amino acid is replaced by a modified amino acid and/or a non-amino acid compound, or a pharmaceutically acceptable salt thereof. | 2011-07-28 |
20110184154 | CELL BROTH CLARIFICATION AND HOST CELL PROTEIN REMOVAL - The present invention relates to a method for clarification of, and removal of host cell proteins from, a cell broth consisting essentially of viable cells, a culture medium and a secreted desired biological substance having an overall positive charge in the cell broth by contacting the cell broth with a particulate anion exchanger, allowing an adequate incubation time to result in formation of a cell pellet and a supernatant layer, separating the resulting cell pellet from the supernatant layer. The present invention further relates to a method for the recovery of a secreted desired biological substance from the cell broth by extracting the secreted desired biological substance from the supernatant layer. | 2011-07-28 |
20110184155 | CARRIER POLYMER PARTICLE, PROCESS FOR PRODUCING THE SAME, MAGNETIC PARTICLE FOR SPECIFIC TRAPPING, AND PROCESS FOR PRODUCING THE SAME - Carrier polymer particles comprising organic polymer particles having a particle diameter of 0.1 to 20 micrometers and a saccharide with which the surface of the organic polymer particles is covered, the organic polymer particles and the saccharide being chemically bonded. | 2011-07-28 |
20110184156 | PRECURSORS FOR DEPOSITION OF METAL OXIDE LAYERS OR FILMS - Rare earth metal precursors, for use in MOCVD techniques have a ligand of the general formula OCR | 2011-07-28 |
20110184157 | Methods of Producing Bacterial Alginates - Methods for mass producing bacterial alginate, bacterial cultures for producing alginate, and pharmaceutical compositions containing bacterial alginate are contemplated. | 2011-07-28 |
20110184158 | HYDRATES OF ERYTHROMYCIN SALTS, PREPARATION AND USE THEREOF - The present invention relates to a macrolide derivative as well as preparation and use thereof. The macrolide derivative of the present invention, i.e., a hydrate of erythromycin salts, has a molecular formula of C | 2011-07-28 |
20110184159 | PROCESS FOR PRODUCTION OF RADIOPHARMACEUTICALS - The present invention relates to novel processes for the production of F-18 labeled radiotracers for Positron Emission Tomography (PET). The invention also comprises radiopharmaceutical kits using these processes. | 2011-07-28 |
20110184160 | NUCLEIC ACID MOLECULE ENCODING CONSENSUS INFLUENZA A HEMAGGLUTININ H1 - Provided herein are nucleic acid sequences that encode novel consensus amino acid sequences of HA hemagglutinin, as well as genetic constructs/vectors and vaccines expressing the sequences. Also provided herein are methods for generating an immune response against one or more Influenza A serotpyes using the vaccines that are provided. | 2011-07-28 |
20110184161 | USE OF MICROARRAYS FOR GENOMIC REPRESENTATION SELECTION - The present invention provides novel methods for reducing the complexity of a genomic sample for further analysis such as direct DNA sequencing, resequencing or SNP calling. The methods use pre-selected immobilized oligonucleotide probes to capture target nucleic acid molecules from a sample containing denatured, fragmented genomic nucleic acid. The disclosed method provides for cost-effective, flexible and rapid enrichment of target nucleic acid from complex biological samples. | 2011-07-28 |
20110184162 | METHOD FOR RAPID ISOLATION OF RNA AND A KIT THEREOF - The present invention relates to a method for rapid isolation of RNA. More particularly, it relates to a method for isolation of RNA using two-solution system. The present invention also relates to a RNA isolation kit. | 2011-07-28 |
20110184163 | Enzymatic Nucleic Acid Synthesis: Compositions and Methods for Inhibiting Pyrophosphorolysis - Nucleotide triphosphate probes containing a molecular and/or atomic tag on a a γ and/or β phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed. | 2011-07-28 |
20110184164 | Pathogen-Resistant Fabrics - A pathogen-resistant fabric comprising one or more photocatalysts capable of generating singlet oxygen from ambient air. The pathogen-resistant fabric may optionally include one or more singlet oxygen traps. | 2011-07-28 |
20110184165 | Aggregate Zeolitic Absorbents, Their Method of Preparation and Their Uses - The invention relates to aggregate zeolitic adsorbents based on faujasite X type zeolite powder having a low silica content and small crystals, exchanged with barium or based on faujasite X type zeolite having a low silica content and small crystals, exchanged with barium and potassium. | 2011-07-28 |
20110184166 | GEOMETRIC SYNTHESIS OF PORPHYRIN RODS - A method of making a compound of Formula I′ | 2011-07-28 |
20110184167 | PROCESS FOR THE PREPARATION OF TEMSIROLIMUS AND ITS INTERMEDIATES - Novel intermediates, process for their preparation and their use in the preparation of therapeutically effective antineoplastic agents, in particular Temsirolimus of formula (I). | 2011-07-28 |
20110184168 | LONG WAVELENGTH THIOL-REACTIVE FLUOROPHORES - Reactive fluorescent dyes compositions and methods of using same are disclosed. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed having thiol-reactive groups. Squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus dyes are disclosed that exhibit a fluorescence emission of at least about 575 nm. Biosensors are disclosed having a binding protein and a squaraine nucleus, Nile Red nucleus, benzodioxazole nucleus, coumarin nucleus or aza coumarin nucleus. | 2011-07-28 |
20110184169 | PROCESS OF ISOLATING ENANTIOMER COMPONENT FROM ENANTIOMER MIXTURES BY PARTICLE-SIZE-CONTROLLED CRYSTALLIZATION - The present invention discloses a process for isolating enantiomer components from a mixture of enantiomers through particle-size-controlled crystallization, comprising the steps of: (a) forming a solution of a mixture of enantiomers (R) and (S) in a solvent in the absence of any further additives or agents; (b) seeding the solution of step (a) simultaneously or consecutively with seed crystals of enantiomer (R) and with seed crystals of enantiomer (S), wherein the seed crystals of enantiomer (R) differ in size and/or in quantity from the seed crystals of enantiomer (S) to allow separation of the crystals composed of a mixture enriched with enantiomer (R) from the crystals composed of a mixture enriched with enantiomer (S); (c) inducing simultaneous crystallization of enantiomer (R) and enantiomer (S); and (d) isolating crystals composed of a mixture enriched with enantiomer (R) from crystals composed of a mixture enriched with enantiomer (S) through size separation of the crystals, preferably through sieving, melting or sedimentation, in particular through sieving. | 2011-07-28 |
20110184170 | METALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME - The present invention relates to an organic electroluminescence device containing a light emitting metallic compound of Chemical Formula 1. In the Chemical Formula 1, M is selected from Ir, Pt, Rh, Re, and Os, and m is 2, provided that m is 1 when M is Pt. | 2011-07-28 |
20110184171 | ACYLATION OF HINDERED AMINES AND FUNCTIONALIZED BIS-PEPTIDES OBTAINED THEREBY - Functionalized bis-peptides as well as other amide-containing compounds are obtained by acylation of hindered amines. The functionalized bis-peptides are useful as shape-programmable nanostructures that are immune to denaturation and that contain arrays of functional groups having designed catalytic, protein-binding and/or sensor capabilities. | 2011-07-28 |
20110184172 | PROCESS FOR THE PREPARATION OF METHYL ESTER OF ROSUVASTATIN - Process for the preparation of enantiomerically pure methyl ester of rosuvastatin has been developed, wherein the crude methyl ester ester is first purified by preparative chromatography, followed by crystallization. | 2011-07-28 |
20110184173 | Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity - The present invention is a compound having the general formula (I), (II), or (III) or a pharmacologically acceptable salt, solvate, or hydrate thereof, and a pharmaceutical composition containing such a compound, or its pharmacologically acceptable ester, or other pharmacologically acceptable derivative thereof as an active ingredient. The compound has an excellent ACAT 2-inhibiting activity by a mechanism different from that of a statin drug and is useful as a therapeutic or prophylactic agent for obesity, adiposis, hyperlipidemia, hypercholesterolemia, disorder of lipid metabolism, and arteriosclerosis, as well as obesity-derived hyperlipidemia, hypercholesterolemia, disorder of lipid metabolism, arteriosclerosis, and hypertension. | 2011-07-28 |
20110184174 | Processes for the Synthesis of Levocetirizine and Intermediates for Use Therein - The present invention provides a compound of formula (IV) | 2011-07-28 |
20110184175 | METHOD FOR PRODUCING BSH DERIVATIVE AND BSH DERIVATIVE - Disclosed is a method for producing a BSH derivative, which comprises a step of addition-reacting BSH with an α,β-unsaturated nitrile compound in the presence of a base. Various BSH derivatives obtained by the method are also disclosed. | 2011-07-28 |
20110184176 | PRODUCING METHOD OF NITROGEN CONTAINING CONDENSED HETEROCYCLIC COMPOUND - Provided is a method for producing a nitrogen-containing condensed heterocyclic compound containing the step of: reacting a compound represented by Formula (1a) or Formula (1b) with a compound represented by Formula (2) under existence of cupper or a cupper ion, and a ligand to produce a nitrogen-containing condensed heterocyclic compound represented by Formula (3a) or Formula (3b): | 2011-07-28 |
20110184177 | CXCR2 INHIBITORS - The invention relates to compounds of the formula I: | 2011-07-28 |
20110184178 | POLYMORPHS OF 5-(3-(ETHYLSULFONYL)PHENYL)-3,8-DIMETHYL-N-(1-METHYLPIPERIDIN-4-YL)-9H-PY- RIDO[2,3-B]INDOLE-7-CARBOXAMIDE AND METHODS OF USE THEREFOR - The invention relates to polymorphic forms of 5-(3-(ethylsulfonyl)phenyl)-3,8-dimethyl-N-(1-methylpiperidin-4-yl)-9h-pyrido[2,3-b]indole-7-carboxamide (referred to herein as Compound I), which has the formula: | 2011-07-28 |
20110184179 | Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy) phenylmethyl)carbamide and its Tartrate Salt and Crystalline Forms - Disclosed herein are methods for synthesizing N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)-phenylmethyl)carbamide. Also disclosed herein is the hemi-tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)-phenylmethyl)carbamide and methods for obtaining the salt. Further disclosed are various crystalline forms of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)-phenylmethyl)carbamide and its hemi-tartrate salt including various polymorphs and solvates. | 2011-07-28 |
20110184180 | Process for Preparing Aryl- and Heteroarylacetic Acid Derivatives - The present invention relates to a novel process for preparing α-arylmethylcarbonyl compound of the formula (III), characterized in that aryl- and heteroarylacetic acids and derivatives thereof of the formula (I) are reacted with α-halomethylcarbonyl compounds of the formula (II) in the presence of a palladium catalyst, of a phosphine ligand, of an inorganic base and of a phase transfer catalyst, optionally using an organic solvent. | 2011-07-28 |
20110184181 | ELECTROCHROMIC MATERIALS AND ELECTROCHROMIC DEVICES USING THE SAME - Disclosed herein are novel electrochromic materials. The electrochromic materials are viologens into which an imidazole derivative is asymmetrically introduced. The electrochromic materials can be used in a variety of electrochromic displays, including electrochromic windows and smart windows. Also disclosed herein are electrochromic devices that use the electrochromic materials. | 2011-07-28 |
20110184182 | COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF - Disclosed herein are novel compounds which are useful as intermediates for producing substituted sulfoxide compounds and a process for producing the same. Further disclosed is a process for producing the substituted sulfoxide compounds used as pharmacologically active agents, employing the novel intermediates of the present invention. | 2011-07-28 |
20110184183 | METHOD FOR PREPARING A NON-HYDRATABLE CRYSTAL FORM - A method is disclosed for preparing a non-hydratable crystal form from a hydratable crystal form of 3-bromo-1-(3-chloro-2-pyridinyl)-N-[4-cyano-2-methyl-6-[(methylamino)-carbonyl]phenyl]-1H-pyrazole-5-carboxamide (Compound 1). | 2011-07-28 |
20110184184 | METHOD FOR SEPARATING AND PURIFYING alpha- UNSATURATED AMINE COMPOUND - A method for purifying an α-unsaturated amine compound represented by Formula (1), the method comprising a step of extracting with water the compound of Formula (1) from a crude product of the α-unsaturated amine compound represented by Formula (1), and a step of extracting with a pyridine solvent the α-unsaturated amine compound of Formula (1) from the aqueous solution containing the compound of Formula (1) obtained in the previous step to obtain a pyridine solvent solution of the compound of Formula (1): | 2011-07-28 |
20110184185 | Methods Of Preparing Thiazolidines - The present invention provides methods of preparing thiazolidines, and in particular methods of preparing ribose-cysteine. | 2011-07-28 |
20110184186 | PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME - The present invention provides a process for preparing thiazole derivatives of formula (I), that activate the delta subtype of the human Peroxisome Proliferator Activated Receptor (hPPAR δ), and also provides compounds of formula (II), (IV), (X), (XI) and (XII), intermediate compounds for preparation of the above compounds of formula (I). | 2011-07-28 |
20110184187 | PROCESS FOR THE PREPARATION OF TETRAZOLE DERIVATIVES FROM ORGANO BORON AND ORGANO ALUMINIUM AZIDES - The present invention relates to a method for preparing substituted tetrazoles, compounds obtained according to this method, new reactants and new tetrazole derivatives. | 2011-07-28 |
20110184188 | Insecticidal Benzenedicarboxamide Derivative - The present invention relates to a novel benzenedicarboxamide derivative and the use thereof as an insecticide having the formula (I) wherein the chemical groups W | 2011-07-28 |
20110184189 | PROCESS FOR THE PREPARATION OF N-(1-BENZO[B]THIEN-2-YLETHYL)-N-HYDROXYUREA - A method of preparation of N-(1-benzo[b]thien-2-ylethyl)-N-hydroxyurea of formula (I) with the use of a reaction of 1-(benzo[b]thien-2-yl)-ethanol of formula (II) with hydroxyurea of formula (III) in organic solvents, organic acids, their mixtures or in mixtures thereof with water, being catalyzed by strongly acidic cation exchangers or various hydrogen sulphates. | 2011-07-28 |
20110184190 | COMPOUNDS USEFUL IN THE SYNTHESIS OF HALICHONDRIN B ANALOGS - In general, the invention features compounds useful for the synthesis of analogs of halichondrin B, such as eribulin or pharmaceutically acceptable salts thereof, e.g., eribulin mesylate. Exemplary compounds are of formula (I), (II), or (III): | 2011-07-28 |
20110184191 | TWO-ZONE FLUIDISED-BED REACTOR | 2011-07-28 |
20110184192 | PROSTAGLANDIN SYNTHESIS AND INTERMEDIATES FOR USE THEREIN - Fused cyclopentane—4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A: | 2011-07-28 |
20110184193 | PROCESS FOR PRODUCING SPIROGLYCOL - In the production of spiroglycol by the reaction of pentaerythritol and hydroxypivalaldehyde in water in the presence of an acid catalyst, (A) a total content of amines and amine salts in hydroxypivalaldehyde is reduced to 1.5% by weight or lower; (B) seed crystals are added to the reaction system before initiating the reaction and/or during the reaction in an amount from 1.5 to 30% by weight on the basis of the total feed amount of pentaerythritol, hydroxypivalaldehyde, water, the acid catalyst and the seed crystals, each being fed into the reaction system; (C) the pH of the reaction system is kept from 0.1 to 4.0 from initiation of the reaction to completion of the reaction; and (D) the sum of a maximum theoretical amount of spiroglycol to be synthesized from pentaerythritol and hydroxypivalaldehyde to be fed into the reaction system and an amount of spiroglycol contained in the seed crystals to be added to the reaction system is controlled within a range from 5 to 35% by weight on the basis of the total feed amount. The spiroglycol produced has an increased particle size. By washing the spiroglycol with a basic solution, the heat stability is improved. | 2011-07-28 |
20110184194 | Surfactant Compositions and Synthesis - Disclosed herein are environmentally benign surfactants including TPGS-550-M, TPGS-750-M and TPGS-1000-M that comprises of diesters composed of racemic α-tocopherol, MPEG-550, MPEG-750 and MPEG-1000, respectively, and a succinic acid fragment. Also disclosed are novel and efficient methods for their synthesis. The surfactants are designed as an effective nanomicelle-forming species for dissolution of hydrophobic compounds and composition and for general use in metal-catalyzed cross-coupling reactions in water. | 2011-07-28 |
20110184195 | PROCESS FOR THE HYDROGENOLYSIS OF FURFURYL DERIVATIVES - The present invention relates to a process for the hydrogenolysis of a furfuryl derivative to 2-methylfuran derivative, comprising: (a) contacting under liquid phase conditions a solution of the furfuryl derivative in a solvent having a boiling point above the boiling point of furfuryl derivative with hydrogen in the presence of a catalyst comprising a hydrogenation compound to form a 2-methylfuran derivative and water, at a temperature and pressure suitable to maintain the furfuryl derivative in the solvent in the liquid phase, and (b) continuously distilling the 2-methylfuran derivative from the reaction mixture. | 2011-07-28 |
20110184196 | Preparation of azide-modified carbon surfaces for coupling to various species - The invention relates to carbon surfaces modified with one or more azide groups. The invention also relates to methods of modifying carbon surfaces with one or more azide groups. | 2011-07-28 |
20110184197 | EFFECTIVE HYDROGENATION PROCESS - The invention relates to an effective process for producing plant stanol by hydrogenating plant sterol in an organic solvent at a hydrogen pressure of 1-200 bar in the presence of a hydrogenation catalyst. | 2011-07-28 |
20110184198 | New Process for Isomerizing Fused Bicyclic Structures and Preparation of Vitamin D Analogs Comprising the Same - The present invention concerns a process of isomerizing trans fused bicyclic derivatives into cis fused bicyclic derivatives and the preparation of vitamin D or analogs thereof comprising said isomerisation step. | 2011-07-28 |
20110184199 | Methods For Producing Paricalcitol - The present invention is directed to novel processes for the preparation of paricalcitol to novel intermediates used in these processes, and to processes for preparation of the novel intermediates. | 2011-07-28 |
20110184200 | DELTA-8 DESATURASE AND ITS USE IN MAKING POLYUNSATURATED FATTY ACIDS - Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding a delta-8 desaturase along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using this delta-8 desaturase in plants and oleaginous yeast are disclosed. | 2011-07-28 |
20110184201 | METHODS AND COMPOSITIONS FOR REFINING LIPID FEED STOCKS - The present invention relates to systems and methods of using fatty acid alkyl ester solutions to refine feed stocks before converting the feed stocks into fatty acid fatty acid alkyl esters. In an embodiment, the invention includes a method for producing fatty acid alkyl esters. The method can include mixing a crude lipid feed stock with a refining solution to form a crude product mixture, the refining solution comprising greater than about 10 wt. % fatty acid alkyl esters. The method can include extracting the liquid phase from the crude product mixture to obtain a purified lipid feed stock. The method can also include reacting the purified lipid feed stock with an alcohol to form a product mixture comprising fatty acid alkyl esters. In an embodiment, the invention includes a method of making a fatty acid alkyl ester composition. The method can include extracting lipids from a corn-based ethanol production byproduct, adding an alcohol solution to the lipids to form a reaction mixture, and contacting the reaction mixture with a metal oxide catalyst. Other embodiments are included herein. | 2011-07-28 |
20110184202 | SURFACE ENHANCED RAMAN SPECTROSCOPY USING SHAPED GOLD NANOPARTICLES - Surface enhanced Raman scattering (SERS) spectra of 4-mercaptobenzoic acid (4-MBA) self-assembled monolayers (SAMs) on gold substrates is presented for SAMs onto which gold nanoparticles of various shapes have been electrostatically immobilized. SERS spectra of 4-MBA SAMs are enhanced in the presence of immobilized gold nanocrystals by a factor of 10 | 2011-07-28 |
20110184203 | PROCESS FOR PREPARING DIENYL-RUTHENIUM COMPLEXES - The present invention relates to a single-stage process for preparing dienyl-ruthenium complexes of the formula Ru(+II)(dienyl) | 2011-07-28 |
20110184204 | CATALYTIC SYSTEMS FOR THE CONVERSION OF HYDROCARBONS TO FUNCTIONALIZED PRODUCTS - This invention discloses methods and processes for selectively converting hydrocarbons such as methane to materials such as alcohols or other materials containing more reactive functionalities. | 2011-07-28 |
20110184205 | REMOVAL OF EXTRANEOUS METALS FROM SILICON COMPOUNDS BY ADSORPTION AND/OR FILTRATION - The invention relates to a process for treating a composition containing silicon compounds, especially organosilanes and/or inorganic silanes, and at least one extraneous metal and/or a compound containing extraneous metal, wherein the composition is contacted with at least one adsorbent and/or a first filter and then a composition in which the content of the extraneous metal and/or of the compound containing extraneous metal has been reduced is obtained. The invention further relates to the use of organic resins, activated carbon, silicates and/or zeolites and/or else of at least one filter with small pore sizes to reduce the level of the compounds mentioned. | 2011-07-28 |
20110184206 | CATALYST FOR PRODUCING CARBOXYLIC ACID ESTERS, PROCESS FOR PRODUCING SAME AND PROCESS FOR PRODUCING CARBOXYLIC ACID ESTERS (AS AMENDED) - Disclosed is a catalyst for use in production of carboxylic acid ester by reacting (a) aldehyde and alcohol, or (b) one or more types of alcohols, in the presence of oxygen; wherein oxidized nickel and X (wherein X represents at least one element selected from the group consisting of nickel, palladium, platinum, ruthenium, gold, silver and copper) are loaded onto a support within the range of the atomic ratio of Ni/(Ni+X) of from 0.20 to 0.99. | 2011-07-28 |
20110184207 | Method of Fabricating Glycol Monoalkyl Ether Acetate Using Acidic Ionic Liquid Catalyst - A new method for fabricating glycol monoalkyl ether acetate (GMAEA) is provided. A Bronsted acidic ionic liquid is used. After some reactions, two layers of materials are formed. A product of GMAEA is obtained at the upper layer. The lower layer is the ionic liquid. Thus, the ionic liquid is reusable for re-fabricating the product. And, furthermore, waste acid is reduced. | 2011-07-28 |
20110184208 | CATALYTIC OXIDATION REACTIONS IN SUPERCRITICAL OR NEAR-SUPERCRITICAL WATER FOR THE PRODUCTION OF AN AROMATIC CARBOXYLIC ACID - An oxidation process for the production of an aromatic carboxylic acid, said process comprising contacting in the presence of a catalyst, within a continuous flow reactor, one or more precursor(s) of the aromatic carboxylic acid with an oxidant, such contact being effected with said precursor(s) and the oxidant in an aqueous solvent comprising water under supercritical conditions or near supercritical conditions, wherein said catalyst comprises copper. | 2011-07-28 |
20110184209 | PROCESS FOR PRODUCING CARBONYL DIFLUORIDE - An object of the invention is to provide efficient, simple and inexpensive processes for the production of carbonyl difluoride, which is an attractive and important compound as a semiconductor etching gas or a semiconductor cleaning gas. | 2011-07-28 |
20110184210 | CONTINUOUS METHODS AND REACATOR USED FOR THE PRODUCTION OF ALKYLAMINES - In the continuous process for preparing alkylamines by reacting C | 2011-07-28 |
20110184211 | Offgas Cleanup in Olefin Hydroformylation - In the hydroformylation of C5-C14 olefins with cobalt catalyst to produce C6-C15 oxygenates, where offgasses from the hydroformylation or cobalt removal step contain volatile cobalt compounds, the cobalt compounds are recovered by scrubbing the offgas with a liquid, and recycling the liquid to the cobalt removal step. Suitable scrubbing liquids are the organic cobalt-depleted hydroformylation reaction product or a downstream derivative thereof, or an aqueous solution of a Co | 2011-07-28 |
20110184212 | PROCESS FOR PREPARING NEOPENTYL GLYCOL BY CRACKING HIGH BOILERS OCCURING IN THE PRODUCTION PROCESS - The present invention relates to a process for obtaining neopentyl glycol by hydrogenating cracking of high-boilers occurring in the production process in the presence of copper-chromite catalysts. The hydrogenating cracking proceeds in the absence of solvent at a temperature of 140 to 220° C. and at pressures of 7 to 28 MPa. | 2011-07-28 |
20110184213 | Fractional Condensation Processes, Apparatuses and Systems - The present invention provides fractional condensation apparatuses, systems and methods that can recover volatile products from highly diluted liquid and vapor feed mixtures with high purity and recovery yield, both in batch and continuous distillation, while being also designed to achieve low-cost and efficient recovery processes. Single apparatuses and columns can be connected to each other to expand or shrink the column length for desired separation. The apparatuses, systems and methods can be applied to separate mixtures with both narrow and wide boiling point ranges. | 2011-07-28 |
20110184214 | PROCESS OF MAKING FLUOROOLEFINS BY THERMAL DECOMPOSITION OF FLUORINATED MATERIALS - Process for producing fluorinated olefins from fluorinated materials, the process comprising thermally decomposing the fluoropolymers into fluoroolefins in a reactor having a feeding zone where the fluorinated materials are fed into the reactor and a decomposition zone where the fluorinated materials are thermally decomposed and wherein the thermal decomposition is carried out in the presence of microwave irradiation. | 2011-07-28 |
20110184215 | BIOMASS PYROLYSIS IN REFINERY FEEDSTOCK - This invention relates to biomass pyrolysis through the use of a hot liquid refinery feedstock as a heat transfer medium, preferably a vacuum gas oil feedstock. | 2011-07-28 |
20110184216 | PREPARATION OF HETEROGENEOUS CATALYSTS USED IN SELECTIVE HYDROGENATION OF GLYCERIN TO PROPENE, AND A PROCESS FOR THE SELECTIVE HYDROGENATION OF GLYCERIN TO PROPENE - The present invention relates to a process of formulating and preparing supported multi-metal catalysts based on metal oxides and inorganic salts of metals. The impregnation technique is employed by two methods: the slurry method and the modified-pH variation method, which are used in two steps for obtaining the catalyst. The present invention also relates to a process called Glycerol to Propene (GTP) process, corresponding to the transformation of glycerol or glycerin to propene. The reaction involved in the process of the present invention is the selective hydrogenation of glycerin, which takes place by contact of the charge of glycerin carried by hydrogen in a continuous stream system on the catalytic bed containing multi-metal catalysts, specifically prepared for this purpose. | 2011-07-28 |
20110184217 | Method of Enhancing an Aromatization Catalyst - A hydrocarbon aromatization process comprising adding a nitrogenate, an oxygenate, or both to a hydrocarbon stream to produce an enhanced hydrocarbon stream, and contacting the enhanced hydrocarbon stream with an aromatization catalyst, thereby producing an aromatization reactor effluent comprising aromatic hydrocarbons, wherein the catalyst comprises a non-acidic zeolite support, a group VIII metal, and one or more halides. Also disclosed is a hydrocarbon aromatization process comprising monitoring the presence of an oxygenate, a nitrogenate, or both in an aromatization reactor, monitoring at least one process parameter that indicates the activity of the aromatization catalyst, modifying the amount of the oxygenate, the nitrogenate, or both in the aromatization reactor, thereby affecting the parameter. | 2011-07-28 |
20110184218 | USE OF SWING PRELIMINARY ALKYLATION REACTORS - Alkylation systems and processes are described herein. The alkylation system generally includes a preliminary alkylation system containing a preliminary alkylation catalyst therein and adapted to contact an aromatic compound and an alkylating agent with the preliminary alkylation catalyst so as to alkylate the aromatic compound and form a preliminary output stream, wherein the preliminary alkylation system includes a first preliminary alkylation reactor and a second preliminary alkylation reactor connected in parallel to the first preliminary alkylation reactor and a primary alkylation system adapted to receive the preliminary output stream and contact the preliminary output stream and the alkylating agent with a primary alkylation catalyst disposed therein so as to form a primary output stream. | 2011-07-28 |
20110184219 | ALKYLATION PROCESS COMPRISING MONITORING IONIC LIQUID CATALYST ACIDITY - A process for determining ionic liquid catalyst deactivation including (a) collecting at least one sample of an ionic liquid catalyst; (b) hydrolyzing the at least one sample to provide at least one hydrolyzed sample; (c) titrating the at least one hydrolyzed sample with a basic reagent to determine a volume of the basic reagent necessary to neutralize a Lewis acid species of the ionic liquid catalyst; and (d) calculating the acid content of the at least one sample from the volume of basic reagent determined in step (c) is described. Processes incorporating such a process for determining ionic liquid catalyst deactivation are also described. These processes are an alkylation process, a process for controlling ionic liquid catalyst activity in a reaction producing by-product conjunct polymers, and a continuous process for maintaining the acid content of an ionic liquid catalyst at a target acid content in a reaction producing by-product conjunct polymers. | 2011-07-28 |
20110184220 | METHODS FOR THE TREATMENT OF RADIATION OR CHEMOTHERAPY-INDUCED TISSUE DAMAGE - The present invention relates to methods for preventing or treating toxicities associated with exposure to ionizing radiation or to chemotherapy. Particularly, the present invention relates to methods for preventing or treating toxicities associated with radiation or chemotherapy comprising administering to a subject in need of such treatment polypeptide complexes comprising an IL-6 linked to a soluble IL-6 receptor, the polypeptide complexes capable of preventing or treating toxicities, particularly xerostomia. | 2011-07-28 |
20110184221 | ELONGATED LIFETIME X-RAY METHOD AND APPARATUS USED IN CONJUNCTION WITH A CHARGED PARTICLE CANCER THERAPY SYSTEM - The system uses an X-ray imaging system having an elongated lifetime. Further, the system uses an X-ray beam that lies in substantially the same path as a charged particle beam path of a particle beam cancer therapy system. The system creates an electron beam that strikes an X-ray generation source located proximate to the charged particle beam path. By generating the X-rays near the charged particle beam path, an X-ray path running collinear, in parallel with, and/or substantially in contact with the charged particle beam path is created. The system then collects X-ray images of localized body tissue region about a cancerous tumor. Since, the X-ray path is essentially the charged particle beam path, the generated image is usable for precisely target the tumor with a charged particle beam. | 2011-07-28 |
20110184222 | BRACHYTHERAPY DEVICE - A brachytherapy device is configured for use in a system having a fluid source. The brachytherapy device includes a balloon assembly including an inflation conduit coupled to a distensible portion. The inflation conduit is configured to facilitate passage of an inflation fluid received from the fluid source to the distensible portion. The distensible portion is configured to respond to the inflation fluid by expanding. The distensible portion has an outer surface with an oval profile. A treatment delivery shaft extends into a region within the distensible portion. The treatment delivery shaft is configured to deliver a treatment material to a location in the region. | 2011-07-28 |
20110184223 | METHODS, APPARATUS, AND SYSTEMS FOR MAGNETIC STIMULATION - A coil suitable for tissue stimulation and especially for transcranial magnetic stimulation (TMS) may be used in conjunction with a pulse generator to induce electric field in the brain with less attenuation in depth compared to existing TMS coils. In an example, a coil winding is formed in a solenoid configuration around the head. Various related features, methods, and embodiments are described. | 2011-07-28 |
20110184224 | SELF-CONTAINED HEART PUMP, AND METHOD IMPLEMENTED IN SUCH A PUMP - A heart pump includes:
| 2011-07-28 |
20110184225 | STEP TRAINER FOR ENHANCED PERFORMANCE USING RHYTHMIC CUES - A person's step length and rate may be measured, for example, through sensors that collect spatial and temporal gait parameter data. The measurements are then used to determine the rate of a rhythmic auditory cue to improve the person's gait. For example, a system links sensors to detect step rate and length to an audio cue provided to headphones, while providing the appropriate algorithms to accomplish real time adjustments to the audio cues as needed to better help change the person's step length vs. step rate ratio in a desired direction depending on therapeutic or performance goals. | 2011-07-28 |
20110184226 | DISSOLVABLE PROTECTIVE TREATMENT FOR AN IMPLANTABLE SUPPORTIVE SLING - The invention provides, in one embodiment, a sling assembly including an implantable supportive sling and a biocompatible dissolvable protective treatment on at least a portion of the sling. | 2011-07-28 |
20110184227 | PROSTHETIC DEVICE AND METHOD OF MANUFACTURING THE SAME - An implantable device for use in tissue and ligament repair comprising at least one knitted section and at least one single continuous fiber traversing the at least one knitted section, the at least one single continuous fiber forming a plurality of traverses extending through the at least one knitted section. The implantable device may comprise at least one single continuous silk fiber. The implantable device is suitable for use in a variety or reconstructive or support applications such as breast reconstruction, mastoplexy, breast augmentation revision, breast augmentation support, standard breast augmentation, chest wall repair, organ support, body contouring, abdominoplasty, facial reconstruction, hernia repair, and pelvic floor repair. | 2011-07-28 |
20110184228 | COMPOSITE SURGICAL IMPLANTS FOR SOFT TISSUE REPAIR - According to one aspect of the invention, composite implants for soft tissue repair a provided which comprise (a) a substantially two-dimensional piece of biologic matrix material and (b) one or more non-absorbable synthetic polymeric filaments. | 2011-07-28 |
20110184229 | LAPAROSCOPIC GASTRIC BAND WITH ACTIVE AGENTS - A gastric banding system is provided which generally includes a gastric band and an active agent, for example, a metabolic agent or satiety inducing agent. The band may be structured to contain the agent and permit controlled release of the agent to the patient while the band is positioned around the stomach. Methods for treating obesity are also provided which include positioning a gastric band on the stomach of a patient and administering a satiety inducing agent to the patient while the gastric band is positioned on the stomach. In one embodiment, the active agent may be contained in a reservoir and dispensed to a portion of the patient's body. | 2011-07-28 |
20110184231 | DEFLECTABLE INSTRUMENT PORTS - An instrument port for a single instrument comprises an elongate tube having a lumen. The elongate tube has a rigid section of fixed shape, and a more distal deflectable section. An actuator is coupled to the rigid section of the elongate tube. The actuator has an instrument pathway in communication with the lumen of the tube. The instrument pathway is positioned such that a distal end of a medical instrument may be inserted through the instrument pathway and the lumen and out the distal end of the lumen into a body cavity. Manipulation of the instrument handle engages actuation elements that extend between the actuator and the deflectable section, causing movement of deflectable section and thus moving the instrument tip within the body. The port includes a mount that can be coupled to a stabilization arm within the operating room, allowing the port to be supported and maintained in a chosen position and orientation. | 2011-07-28 |
20110184232 | ENDOSCOPIC SURGICAL INSTRUMENT - A series of integrally formed segments ( | 2011-07-28 |
20110184233 | INSTRUMENT FOR AN ENDOSCOPE - An endoscope instrument includes an insertion tube of longitudinal axis possessing a proximal portion for connection to an actuation support and a distal portion presenting an outlet section occupied by a viewing zone and by at least one outlet orifice for passing at least one appliance for occupying a retracted position inside the tube and a working position in which the appliance occupies at least a portion of the outlet section. The distal portion of the insertion tube includes at least one radially deformable wall over a portion of its length extending from the outlet section, enabling the outlet section of the distal portion of the tube to be increased on the appliance passing from its retracted position in which the appliance does not stress the deformable wall to its working position in which the deformable wall is stressed radially. | 2011-07-28 |
20110184234 | DEVICE AND METHOD FOR MINIMALLY INVASIVE SPINAL INTERVENTION - The invention proposes a device for minimally invasive intervention in the skeletal region, in particular on the spinal column, having at least the following two elements:
| 2011-07-28 |
20110184235 | CAPSULE TYPE ENDOSCOPE INCLUDING MAGNETIC DRIVE - The present invention discloses a magnet driven capsule type endoscope comprising an image recording unit as well as an image data processing unit, a position sensor for providing data about the position of the capsule type endoscope with respect to the direction of gravitation, a data transmitting unit, an energy source for supplying the units and the sensor with energy and a permanent magnet. In accordance with the invention, the permanent magnet is arranged offset with respect to the center of gravity and to the geometrical center of the capsule type endoscope. | 2011-07-28 |
20110184236 | IMAGING APPARATUS, ENDOSCOPE SYSTEM, AND METHOD OF CONTROLLING IMAGING APPARATUS - An imaging apparatus includes an imaging section that images an object, an observation mode setting section that sets an observation mode when the imaging section images the object, and a control section that controls an image read mode in which an image is read from the imaging section and a in-focus object plane of the imaging section based on the observation mode set by the observation mode setting section. | 2011-07-28 |
20110184237 | ENDOSCOPE IMAGE PICK-UP APPARATUS - An image pick-up unit inserted in the body picks up an image of the body, and transmits by radio the image to an extra-corporeal unit which is arranged outside the body. The image pick-up unit includes an image pick-up portion capturing an image, a data transmitting portion for transmitting the image obtained by the image pick-up portion to the extra-corporeal unit at a plurality of transmitting ratios, a characteristic amount detecting portion for detecting a predetermined amount of characteristics based on the image, and a determining portion for determining a valid image based on an output from the characteristic amount detecting portion. The data transmitting portion controls the data transmitting ratio in accordance with the determining result of the determining portion. | 2011-07-28 |
20110184238 | IMAGE-BASED GLOBAL REGISTRATION SYSTEM AND METHOD APPLICABLE TO BRONCHOSCOPY GUIDANCE - A global registration system and method identifies bronchoscope position without the need for significant bronchoscope maneuvers, technician intervention, or electromagnetic sensors. Virtual bronchoscopy (VB) renderings of a 3D airway tree are obtained including VB views of branch positions within the airway tree. At least one real bronchoscopic (RB) video frame is received from a bronchoscope inserted into the airway tree. An algorithm according to the invention is executed on a computer to identify the several most likely branch positions having a VB view closest to the received RB view, and the 3D position of the bronchoscope within the airway tree is determined in accordance with the branch position identified in the VB view. The preferred embodiment involves a fast local registration search over all the branches in a global airway-bifurcation search space, with the weighted normalized sum of squares distance metric used for finding the best match. | 2011-07-28 |
20110184239 | METHODS AND SYSTEMS FOR DISABLING AN ENDOSCOPE AFTER USE - Various embodiments comprise endoscopes for viewing inside a cavity of a body such as a vessel like a vein or artery. These endoscopes may include a usage detector and a disabling device coupled to the usage detector, wherein the disabling device is configured to disable the endoscope at least partly in response to an electrical, optical, and/or mechanical output from the usage detector. | 2011-07-28 |
20110184240 | METHOD FOR CONTACT-FREE MAGNETIC NAVIGATION - In a method and a system for contact-free magnetic navigation of a magnetic body in a work space that is at least partially filled with a fluid, a thickening agent is added to the fluid. The use of a thickening agent as an additive for such a fluid is also described. | 2011-07-28 |
20110184241 | EXTENDABLE ARTICULATED PROBE DEVICE - An articulate probe device includes a first mechanism, a second mechanism, and an overtube mechanism. The first mechanism includes a proximal link which is movable coupled to a first intermediate link, a plurality of intermediate links, and a distal link which is moveably coupled to a second one of the intermediate links. The second mechanism includes a proximal link which is movable coupled to a first intermediate link, a plurality of intermediate links, and a distal link which is moveably coupled to a second one of the intermediate links. The overtube mechanism includes a proximal link which is movable coupled to a first intermediate link, a plurality of intermediate links, and a proximal link which is moveably coupled to a second one of the intermediate links. Further, at least one of the first mechanism, second mechanism, and overtube mechanism is steerable and extendable beyond the other mechanisms. | 2011-07-28 |
20110184242 | BENDABLE STRUCTURE AND A METHOD FOR BENDING A STRUCTURE - The invention relates to a bendable structure | 2011-07-28 |
20110184243 | ENDOSCOPE WITH DIFFERENT COLOR LIGHT SOURCES - Disclosed are systems and methods involving an endoscope system having a plurality of different illumination sources. Such illumination sources can be controlled to provide various illumination effects. In certain embodiments, illumination sources can be controlled so that resulting outputs can be combined to yield, for example, an intensity profile that approximates a desired source such as a Xenon lamp. In certain embodiments, illumination sources can be activated in sequence so as to allow, for example, use of a monochromatic detector to generate a color image. In certain embodiments, illumination sources can be controlled so as to allow switching between two or more illumination modes. | 2011-07-28 |
20110184244 | MEDICAL EQUIPMENT AND ENDOSCOPE APPARATUS - A medical equipment includes an optical connector that detachably connects a plug to a receptacle provided in an equipment main body to optically connect a plug-side optical fiber fixed to the plug and a receptacle-side optical fiber fixed to the receptacle. The plug and the receptacle have plural engagement pairs each having a protrusion that protrudes in an insertion direction of the plug and an engagement part that is adapted to be engaged with the protrusion. Engagement beginning positions of the engagement pairs where the protrusions and the engagement parts begin to engage are different along the insertion direction. Each engagement pair has a narrower engagement gap between the protrusion and the engagement part than that between the protrusion and the engagement part of any pair which begin to engage earlier as the plug is inserted than the protrusion and the engagement part of each engagement pair. | 2011-07-28 |
20110184245 | TISSUE MONITORING SURGICAL RETRACTOR SYSTEM - An apparatus for monitoring the characteristics of tissue adjacent a surgical site and communicating that information to a health care provider includes a retractor, a sensor, and a processing system. The sensor is disposed on the retractor and is configured to measure a parameter indicative of at least one characteristic of the tissue adjacent the first or the second blade. The processing system is in communication with the sensor and configured and arranged to receive information from the sensor indicative of the measured parameter. It includes a threshold stored therein indicative of excessive trauma to the tissue and it is configured in a manner such that it compares the received information to the stored threshold and communicates information to the health care provider regarding the comparison. | 2011-07-28 |
20110184246 | SURGICAL RETRACTOR - A surgical retractor including a pair of handles mounted for pivotal movement about a pivot pin, a pair of arm members each terminating at a distal end in a downwardly depending blade and attachable to a respective handle at a proximal end. On application of hand pressure by an operator to the pair of handles of the surgical retractor rotates each handle and arm member about the pivot pin and causes the blades to move apart so that in use in a surgical site the blades abut against and retract tissue matter. | 2011-07-28 |
20110184247 | COMPREHENSIVE MANAGEMENT OF HUMAN HEALTH - A health guidance system receives health information from input devices and other sources, tracks one or more health goals, and enforces those goals by acting upon other devices. The health guidance system collects health information to paint a comprehensive picture of the user's health. The system uses the information it collects to interact with a variety of devices to enforce the user's health goals and ensure accountability. Thus, the health guidance system provides a comprehensive software system for collecting health information and using that information to produce positive changes in the health of users. | 2011-07-28 |
20110184248 | STORAGE MEDIUM HAVING STORED THEREIN INFORMATION PROCESSING PROGRAM, INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD, AND INFORMATION PROCESSING SYSTEM - A storage medium is provided having stored therein an information processing program executable by a computer of an information processing device which performs predetermined processes based on biological parameters acquired from a user. The information processing program causes the computer to function as: first biological parameter acquisition means for acquiring a first biological parameter from the user during a first period; second biological parameter acquisition means for acquiring a second biological parameter from the user, within the first period, during the acquisition of the first biological parameter, or on and after a first time point after the acquisition of the first biological parameter; and first process execution means for executing a first process from the first time point, based on the first biological parameter and the second biological parameter. | 2011-07-28 |
20110184249 | REMOTE PATIENT MONITORING SYSTEM - The remote patient monitoring system includes a camera and radio connection device having electronic circuitry disposed in a housing. The device facilitates connection of interchangeable cameras and reconfigurable radios for remote monitoring of visually observable health indicia of a patient by a remotely located health professional. The system may also include a remote server for management of a plurality of patient sites and monitoring devices. The patient health related video images are digitally transmitted from the patient site to the remote health care provider over the Internet. | 2011-07-28 |
20110184250 | EARLY WARNING METHOD AND SYSTEM FOR CHRONIC DISEASE MANAGEMENT - A computer-implemented method and system are provided for assisting a plurality of patients manage chronic health conditions. The method, for each patient, comprises: (a) receiving information from the patient or a member of a patient care network on an expected patient activity at a given future time period; (b) determining expected transient local ambient conditions in the patient's surroundings during the expected patient activity at the given future time period; (c) predicting health exacerbations for the patient using a stored computer model of the patient based on a desired patient control set-point range, the expected patient activity, and the expected transient local ambient conditions; and (d) proactively sending a message to the patient or a member of the patient care network before the given future time period, the message alerting the patient or a member of the patient care network of the predicted health exacerbations for the patient and identifying one or more corrective actions for the patient to avoid or mitigate the predicted health exacerbations. | 2011-07-28 |
20110184251 | BONE MINERAL DENSITY RATIOS AS A PREDICTOR OF OSTEOARTHRITIS - The present invention relates to systems, compositions, and methods for using bone mineral density ratios as a predictor of osteoarthritis. In particular, the present invention relates to comparing ratios of bone mineral density involving bones that are periarticular to determine a risk assessment for features of osteoarthritis. | 2011-07-28 |