30th week of 2009 patent applcation highlights part 38 |
Patent application number | Title | Published |
20090186995 | Production of Propylene-Based Polymers - In a process for producing a propylene-based olefin homopolymer or copolymer, a monomer composition comprising propylene is contacted with a polymerization catalyst system under homogeneous polymerization conditions (such as solution, supersolution or supercritical conditions), wherein the polymerization catalyst system includes an activator and a bridged bis-indenyl transition metal (group 4) compound substituted with a carbazole (unsubstituted or substituted) at the 4 position. | 2009-07-23 |
20090186996 | HAFNIUM COMPLEXES OF CARBAZOLYL SUBSTITUTED IMIDAZOLE LIGANDS - Hafnium complexes of carbazolyl substituted imidazol ligands and their use as components of olefin polymerization catalyst compositions are disclosed. | 2009-07-23 |
20090186997 | PROCESS FOR PRODUCING FLUOROELASTOMERS - An emulsion polymerization process for the production of fluoroelastomers is disclosed wherein at least one fluorosurfactant is employed as dispersant, said fluorosurfactant being a fluoroalkylphosphoric acid ester of the formula X—Rf—(CH | 2009-07-23 |
20090186998 | PARYLENE VARIANTS AND METHODS OF SYNTHESIS AND USE - Fluorinated paracyclophane compounds represented by the formula: | 2009-07-23 |
20090186999 | Low melt flow rate (MFR) propylene based polymers for injection stretch blow molding - Injection stretch blow molded (ISBM) articles and processes for forming the same are described herein. The articles include a propylene based polymer having a melt flow rate of less than 10 g/10 min. | 2009-07-23 |
20090187000 | METHOD FOR PRODUCING CELLULOSE ACYLATE RESIN FILM - A cellulose acylate resin film which can suppress generation of color nonuniformity even after exposure to high temperature and high humidity when incorporated in a liquid crystal display element can be produced. The cellulose acylate resin film is heat-treated at a temperature of Tg−30° C. to Tg+20° C., Tg representing the glass transition temperature of the cellulose acylate resin, for 10 seconds to 600 seconds while conveying the cellulose acylate resin film at a tension of 2 N/cm | 2009-07-23 |
20090187001 | Metathesis Interpolymers Having Terminal Functional Group(s) - The disclosure relates to unsaturated metathesis interpolymers having at least one or more specified terminal functional groups. The interpolymers are prepared by metathesis polymerization, and are selected from 1,5-cyclooctadiene and cyclopentene, 1,5-cyclooctadiene and cyclooctene, and cyclooctene and cyclopentene interpolymers. | 2009-07-23 |
20090187002 | Composite Solid Phase Polymerization Catalyst - The invention is a method for making condensation polymers, such as polyethylene terephthalate polyester. The method includes introducing to a polycondensation reaction a catalyst system that includes a coordination catalyst and a composite catalyst, which includes an acid component and an auxiliary component. | 2009-07-23 |
20090187003 | THERMOSETTING RESIN, THERMOSETTING COMPOSITION CONTAINING SAME, AND MOLDED PRODUCT OBTAINED FROM SAME - An object of the invention is to provide a thermosetting resin excellent in dielectric characteristics and heat resistance, and to provide a thermosetting composition comprising the thermosetting resin, as well as a molded product, substrate material for electronic devices and so forth obtained from the thermosetting resin. The present invention provides a thermosetting resin having a dihydrobenzoxazine ring structure represented by formula (I) in a main chain thereof, a thermosetting composition comprising the thermosetting resin, as well as a molded product, substrate material for electronic devices and so forth obtained from the thermosetting resin. | 2009-07-23 |
20090187004 | EXPRESSION SYSTEM FOR ENHANCING SOLUBILITY AND IMMUNOGENEICITY OF RECOMBINANT PROTEINS - Expression system for enhancing solubility and immunogenicity of recombinant proteins. The expression system includes a protein expression vector that contains a chimeric gene encoding a chimeric protein comprising: (a) a first polypeptidyl fragment at the N-terminal end of the chimeric protein, containing a protein transduction domain (PTD), or a fragment thereof, having HIV Tat PTD activity; (b) a second polypeptidyl fragment at the C-terminal end of the first polypeptidyl fragment, containing a J-domain, or a fragment thereof, having heat shock protein 70 (Hsp70)-interacting activity; and (c) a third polypeptidyl fragment at the C-terminal end of the second polypeptidyl fragment, containing a target protein or polypeptide. | 2009-07-23 |
20090187005 | ENHANCED PURIFICATION OF ANTIBODIES AND ANTIBODY FRAGMENTS BY APATITE CHROMATOGRAPHY - Methods are disclosed for use of apatite chromatography, particularly without reliance upon phosphate gradients, for purification or separation of at least one intact non-aggregated antibody, or at least one immunoreactive antibody fragment, from an impure preparation. Integration of such methods into multi-step procedures with other fractionation methods are additionally disclosed. | 2009-07-23 |
20090187006 | NOVEL PROTEIN, A GENE ENCODING THEREFOR AND A METHOD OF USING THE SAME - An object of the present invention is to search and identify novel antifungal proteins capable of inhibiting the growth of plant pathogenic microorganisms including | 2009-07-23 |
20090187007 | ANTI-HER2 ANTIBODY VARIANTS - The present invention concerns novel antibody variants, particularly anti-HER2 antibody variants having substitutions at positions within the variable domains of the heavy and light chains | 2009-07-23 |
20090187008 | ADSORBENT ADSORBING ANTIBODY AGAINST BETA 1 ADRENORECEPTOR - The present invention provides a peptide which selectively adsorbs an anti-β1 adrenoreceptor antibody being one of the contributing factors in dilated cardiomyopathy. The peptide of the invention can be immobilized on a carrier in a short period of time with rarely inducing side reactions, and adsorbent for adsorbing an anti-β1 adrenoreceptor antibody can be produced with good efficiency by using the peptide. In addition, the present invention provides an adsorbent comprising such peptide immobilized on a carrier, an adsorber wherein such adsorbent is used, and a method for adsorbing an anti-β1 adrenoreceptor antibody. The adsorbent and adsorber according to the invention can efficiently deprive an anti-β1 adrenoreceptor antibody-containing liquid, in particular body fluid, of the antibody. | 2009-07-23 |
20090187009 | SCALE-UP METHODS AND SYSTEMS FOR PERFORMING THE SAME - The present invention provides methods of and systems for translating conditions from a small-volume experiment to a larger-volume experiment. | 2009-07-23 |
20090187010 | Method of arranging ferritin and method of arranging inorganic particles - To provide a method of arranging ferritin by which a high rate of the number of the molecular film spots on which sole ferritin molecule was arranged in effect, with respect to total number of the molecular film spots provided for arranging ferritin (sole arrangement rate) is achieved is objected to. Specifically, in Fer8 ferritin having a sequence excluding 7 amino acids of from the second to the eighth, from an amino acid sequence (Fer0 sequence) translated from a naturally occurring DNA sequence, lysine at position | 2009-07-23 |
20090187011 | Method of serum pre-treatment for glycomic analysis - A means for pre-treatment in glycomic analysis of a glycoprotein is provided by the present invention. | 2009-07-23 |
20090187012 | POLARIZER, COATING LIQUID, AND MANUFACTURING METHOD FOR POLARIZER - A polarizer of the present invention comprises an azo compound which is represented by the following general formula (I). In the general formula (I), Q | 2009-07-23 |
20090187013 | SYNTHETIC HEPARIN PENTASACCHARIDES - Preparation of synthetic monosaccharides, disaccharides, trisaccharides, tetrasaccharides and pentasaccharides for use in the preparation of synthetic heparinoids. | 2009-07-23 |
20090187014 | Novobiocin Analogues - Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders, as well as cancer. | 2009-07-23 |
20090187015 | Process For Preparing Substituted Benzimidazole Compounds - The invention relates to new methods of preparing substituted benzimidazole compounds, such as 2-bromo-5,6-dichlorobenzimidazole, which are useful in the preparation of compounds having antiviral activity. | 2009-07-23 |
20090187016 | METHOD FOR PRODUCING CELLULOSE ACETALS - The present invention describes a process for preparing acetals of polysaccharides, oligosaccharides or disaccharides by dissolving these in at least one ionic liquid and reacting them with a vinyl ether. The acetalated polysaccharides or oligosaccharides obtained in this way can be crosslinked by treatment with acid. The present invention also provides acetals of polysaccharides, oligosaccharides or disaccharides and also crosslinked polysaccharides or oligosaccharides. | 2009-07-23 |
20090187017 | PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED BETA-AMINO ACID DERIVATIVES - The present invention relates to a process for the organo-catalysed kinetic racemate resolution of compounds of the general formula (II). It is thus possible through the action of catalytic amounts of enantiomerically enriched compounds of the general formula (Ia) or (Ib) to obtain on the one hand enantiomerically enriched optionally N-acylated β-amino acid esters and on the other hand enantiomerically enriched 4,5-dihydrooxazin-6-ones (oxazinones). The corresponding enantiomerically enriched β-amino acids can be formed from both easily separable classes of compounds by simple hydrolysis. | 2009-07-23 |
20090187018 | Manufacture of Pure Hydralazine Salts - The present invention provides an improved process of preparing hydralazine hydrochloride, which involves the preparation of 1-chlorophthalazine salt and further reacting with hydrazine followed by purification of hydralazine hydrochloride, which is free of phosphate, does not contain any individual impurities more than 0.05%, total impurities less than 0.5%, and a hydrazine content of not more than 0.001 %, and preferably less than 0.0003%. One benefit of improved purity is enhanced storage stability. | 2009-07-23 |
20090187019 | Process for preparing diisopropyl((1-(hydroxymethyl)-cyclopropyl)oxy)methylphosphonate - The present invention relates to a new process for preparing diisopropyl {[1-(hydroxymethyl)-cyclopropyl]oxy}methylphosphonate (2), which is a key intermediate for synthesizing an antiviral (particularly, against hepatitis B virus) nucleoside analogue. The present invention also relates to new intermediates, and a process for preparing the antiviral nucleoside analogue from the compound (2) prepared according to the present invention. | 2009-07-23 |
20090187020 | Process And Intermediate For Preparation Of Donepezil - The invention relates to new compounds of formula (III): | 2009-07-23 |
20090187021 | INDANE COMPOUNDS AS CCR5 ANTAGONISTS - The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS). | 2009-07-23 |
20090187022 | Crystalline clopidogrel hydrobromide and processes for preparation thereof - Provided are crystalline forms of clopidogrel hydrobromide and processes for their preparation. | 2009-07-23 |
20090187023 | POLYMORPHIC FORMS OF 3-(4-AMINO-1-OXO-1,3 DIHYDRO-ISOINDOL-2-YL))-PIPERIDINE-2,6-DIONE - Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione are disclosed. Compositions comprising the polymorphic forms, methods of making the polymorphic forms and methods of their use are also disclosed. | 2009-07-23 |
20090187024 | ROPIVACAINE HYDROCHLORIDE ANHYDRATE AND THE PREPARATION THEREOF - The invention pertains to a process for preparing stable anhydrous Ropivacaine hydrochloride, the process involving preparing Ropivacaine hydrochloride from Ropivacaine base, wherein Ropivacaine base is provided having a chiral purity of more than 95%, and wherein the isolation involves the use of isopropanol and hydrochloride, and is performed under water-free conditions. Ropivacaine base may be provided at high chiral purity by N-propylating L-pipecolic acid 2,6-xylidide hydrochloride in the presence of a phase transfer catalyst, wherein the reaction involves a biphasic reaction mixture containing an alkaline aqueous phase and an organic phase. The invention further pertains to stable anhydrous Ropivacaine hydrochloride obtainable by the above process. | 2009-07-23 |
20090187025 | Pharmaceutical composition for promoting angiogenesis - The present invention provides a pharmaceutical composition for promoting angiogenesis, which has an angiogenesis promoting action even in a vascular culturing system without effect of microcirculation. A pharmaceutical composition for promoting angiogenesis of the present invention comprises at least one compound selected from a group consisting of a piperidine compound represented by the general formula (1) or salts thereof: | 2009-07-23 |
20090187026 | Diastereomeric purification of rosuvastatin - The invention relates to diastereomerically pure rosuvastatin and processes for preparing diastereomerically pure rosuvastatin and its intermediates. | 2009-07-23 |
20090187027 | PROCESSES AND REAGENTS FOR SULFURIZATION OF OLIGONUCLEOTIDES - The present invention relates to processes and reagents for oligonucleotide synthesis and purification. One aspect of the present invention relates to compounds useful for activating phosphoramidites in oligonucleotide synthesis. Another aspect of the present invention relates to a method of preparing oligonucleotides via the phosphoramidite method using an activator of the invention. Another aspect of the present invention relates to sulfur-transfer agents. In a preferred embodiment, the sulfur-transfer agent is a 3-amino-1,2,4-dithiazolidine-5-one. Another aspect of the present invention relates to a method of preparing a phosphorothioate by treating a phosphite with a sulfur-transfer reagent of the invention. In a preferred embodiment, the sulfur-transfer agent is a 3-amino-1,2,4-dithiazolidine-5-one. Another aspect of the present invention relates to compounds that scavenge acrylonitrile produced during the deprotection of phosphate groups bearing ethylnitrile protecting groups. In a preferred embodiment, the acrylonitrile scavenger is a polymer-bound thiol. Another aspect of the present invention relates to agents used to oxidize a phosphite to a phosphate. In a preferred embodiment, the oxidizing agent is sodium chlorite, chloramine, or pyridine-N-oxide. Another aspect of the present invention relates to methods of purifying an oligonucleotide by annealing a first single-stranded oligonucleotide and second single-stranded oligonucleotide to form a double-stranded oligonucleotide; and subjecting the double-stranded oligonucleotide to chromatographic purification. In a preferred embodiment, the chromatographic purification is high-performance liquid chromatography. | 2009-07-23 |
20090187028 | Process for preparing Chiral Dipeptidyl Peptidase -IV Inhibitor Intermediates - A novel process is provided for the preparation of chiral trans-2,3-disubstituted 5-oxotetrahydropyrans of structural formula (I): | 2009-07-23 |
20090187029 | PROCESS FOR MAKING SALTS OF N-HYDROXY-3-[4-[[[2-(2-METHYL-1H-INDOL-3-YL)ETHYL]AMINO]METHYL]PHENYL]-2E- -2-PROPENAMIDE - Salts of N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide are prepared by various methods. | 2009-07-23 |
20090187030 | PROCESS FOR CONTINUOUSLY PREPARING N-ETHYL-2-PYRROLIDONE (NEP) - Process for the continuous preparation of N-ethyl-2-pyrrolidone (NEP) by reacting gamma-butyrolactone (GBL) with monoethylamine (MEA) in the liquid phase, wherein GBL and MEA are used in a molar ratio in the range from 1:1.08 to 1:2 an the reaction is carried out at a temperature in the range from 320 to 420° C. and an absolute pressure in the range from 70 to 120 bar. | 2009-07-23 |
20090187031 | Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof - Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided. | 2009-07-23 |
20090187032 | INDUSTRIAL PROCESS FOR THE SYNTHESIS OF 17alpha-ACETOXY-11beta-[4-(N,N-DIMETHYL-AMINO)-PHENYL]-19-NORPREGNA-4,9-D- IENE-3,20-DIONE AND NEW INTERMEDIATES OF THE PROCESS - The present invention relates to a new industrial process for the synthesis of solvate-free 17α-acetoxy-11β-[4-(N,N-dimethyl-amino)-phenyl]-19-norpregna-4,9-diene-3,20-dione [CDB-2914] of formula (I) which is a strong antiprogestogene and antiglucocorticoid agent. The invention also relates to compounds of formula (VII) and (VIII) used as intermediates in the process. | 2009-07-23 |
20090187033 | INTEGRATED METHOD FOR THE PREPARATION OF TRIOXANE FROM FORMALDEHYDE - An integrated process for preparing trioxane from formaldehyde, comprising the steps of:
| 2009-07-23 |
20090187034 | PROCESS FOR THE PREPARATION OF STIRIPENTOL PARTICLES HAVING A DEFINED PARTICLE SIZE DISTRIBUTION - The invention relates to a process for the preparation of stiripentol particles having a defined particle size distribution. | 2009-07-23 |
20090187035 | Process for production of fatty acid alkyl esters - A system and method for producing fatty acid alkyl esters is provided. The method includes forming a reactant stream, which includes triacylglycerides, alkanol, basic transesterification catalyst and, optionally, glycerol, and mixing the reactant stream under high shear mixing conditions to provide a mixed stream comprising fatty acid alkyl ester. | 2009-07-23 |
20090187036 | Nickel Compositions And Methods of Making the Same - The present invention is directed to nickel compositions and methods for making nickel oxide compositions, specifically, such metal oxide compositions having high surface area, high metal/metal oxide content, and/or thermal stability with inexpensive and easy to handle materials. | 2009-07-23 |
20090187037 | SYNTHESIS OF DIFUNCTIONAL OXYETHYLENE-BASED COMPOUNDS - A method of reacting a toluenesulfonyl-terminated polyoxyethylene compound having the formula CH | 2009-07-23 |
20090187038 | REAGENTS AND METHODS FOR THE BETA-KETO AMIDE SYNTHESIS OF A SYNTHETIC PRECURSOR TO IMMUNOLOGICAL ADJUVANT E6020 - This invention relates to the synthesis for a precursor of E6020, compound 26, via a β-keto amide alcohol intermediate, compound 22. The synthesis reacts compound 22 with compound 25 and the resultant intermediate is oxidized to produce compound 26, the precursor to E6020. Compounds 22 and 25, and their crystalline forms, represent separate embodiments of the invention. The invention also relates to compounds of formulas (3) and (4) and processes for their preparation. | 2009-07-23 |
20090187039 | Production of 3-pentenenitrile from 1,3-butadiene - A process is described for preparing 3-pentenenitrile by hydrocyanating 1,3-butadiene, wherein 1,3-butadiene is reacted with hydrogen cyanide in the presence of at least one catalyst and the stream resulting therefrom is purified distillatively, the bottom temperature during the distillation not exceeding 140° C. | 2009-07-23 |
20090187040 | FENOFIBRIC ACID POLYMORPHS; METHODS OF MAKING; AND METHODS OF USE THEREOF - Disclosed are new methods of making the fenofibric acid polymorphs as well as formulations prepared therefrom and uses thereof. | 2009-07-23 |
20090187041 | ESTERS OF (2-HYDROXY-3-OXO-CYCLOPENT-1-ENYL) ACETIC ACID AND THEIR USE FOR PREPARING (-)-R-HOMOCITRIC ACID GAMMA-LACTONE, (+)-S-HOMOCITRIC ACID GAMMA-LACTONE AND THE CORRESPONDING (-)-R-HOMOCITRIC ACID AND (+)-S-HOMOCITRIC ACID SALTS - Archiral (2-hydroxy-3-oxo-cyclopent-1-enyl) acetic acid) alkyl, alkylphenyl and phenyl esters, and a simple and efficient method for the synthesis of both enantiomers of homocitric acid gamma-lactone and the corresponding salts from these esters are described. The method is based on asymmetric oxidation of esters, and the steps of basic and acidic hydrolysis and final acidic lactonization of the homocitric acid into homocitric acid gamma-lactone. The homocitric acid salts are obtained after basic treatment of homocitric acid gamma-lactone. The esters, conditions and reagents used in chemical conversion and separating products are important constituents affording efficient and simple method for production of homocitric acid gamma-lactone and homocitric acid salts. | 2009-07-23 |
20090187042 | METHOD FOR PRODUCING ESTER CONDENSED PRODUCT - The present invention is to provide a method for preparing an ester condensate and a catalyst therefore; wherein the method enables synthesis of enormous amounts of ester condensates comprising a specific structure in good yield, by a reaction of carboxylic acid and alcohol in equimolar amounts, while generation of by-products is prevented; wherein the catalyst exhibits good catalytic efficiency as a catalyst for use, the use of the catalyst in small amount is sufficient, and the catalyst is reusable and can be used repeatedly; therefore, the method for preparing an ester condensate of the present invention and the catalyst therefore can be applied to industrial methods which are preferable in view of green chemistry. Esterification reaction is performed by using a catalyst comprising a zirconium(IV) compound and/or a hafnium(IV) compound and an iron compound and a gallium compound. It is preferable that the zirconium(IV) compound is a compound represented by Zr(OH) | 2009-07-23 |
20090187043 | Control of impurities in product glacial acetic acid of rhodium-catalyzed methanol carbonylation - The present invention relates to carbonylation of methanol, methyl acetate, dimethyl ether or mixtures thereof to produce glacial acetic acid, and more specifically to the manufacture of glacial acetic acid by the reaction of methanol, methyl acetate, dimethyl ether or mixtures thereof with carbon monoxide wherein the product glacial acetic acid contains low impurities. | 2009-07-23 |
20090187044 | FLUOROSULFONYL GROUP-CONTAINING COMPOUND, METHOD FOR ITS PRODUCTION AND POLYMER THEREOF - A compound containing two fluorosulfonyl groups which are groups convertible to sulfonic acid groups, an intermediate therefor, and methods for their production with high productivity, are provided. Also provided are a fluorosulfonyl group-containing polymer obtained by polymerizing such a compound, and a sulfonic acid group-containing polymer obtained from such a polymer. | 2009-07-23 |
20090187045 | PROCESS FOR PREPARING MONOMETHYLHYDRAZINE - The present invention relates to a process for preparing monomethylhydrazine by methylating hydrazine or hydrazinium hydrochloride or hydrazinium dihydrochloride with methyl chloride and/or a methano/HCl mixture, characterized in that the reaction mixture formed in the methylation is reacted with an organic base from the group of the alkylamines or alkanolamines and monomethylhydrazine is removed by distillation from the reaction mixture in a low boiler fraction and the low boiler fraction is optionally subjected to a further distillation. | 2009-07-23 |
20090187046 | Process to Produce Prostratin and Structural or Functional Analogs Thereof - This invention concerns a process to convert a hydroxyl group (bold in R | 2009-07-23 |
20090187047 | PROCESS FOR PRODUCING PHENOL AND METHYL ETHYL KETONE - A process for producing phenol and methyl ethyl ketone comprises contacting benzene and a C | 2009-07-23 |
20090187048 | Reactor for Preparing Organic Peroxides Via the Intermediate of a Solid Hydroperoxide - A reactor which comprises a vessel ( | 2009-07-23 |
20090187049 | Production of propylene glycol monoalkyl ether - The invention is a process for producing a propylene glycol monoalkyl ether which comprises first reacting propylene oxide and an alcohol in the presence of an alkali or alkaline earth metal alkoxide catalyst to produce an alkoxylation mixture comprising propylene glycol monoalkyl ether; distilling the alkoxylation mixture to produce a first overhead stream comprising propylene oxide and alcohol and a first bottoms stream comprising propylene glycol monoalkyl ether; and then distilling the first bottoms stream to produce purified propylene glycol monoalkyl ether as a second overhead stream. The reaction and/or one or more of the distillation steps occur in the presence of an alkali metal borohydride. The process produces propylene glycol monoalkyl ether with low UV absorbance and reduced carbonyl impurities. | 2009-07-23 |
20090187050 | METHOD FOR THE SEPARATION OF POLYMERIC BY-PRODUCTS FROM 1,4-BUTYNEDIOL - The present invention relates to a process for purifying 1,4-butynediol, which comprises compressing 1,4-butynediol to from 50 to 1500 bar, depressurizing it, waiting for phase separation to occur after depressurization and separating off the bottom phase, and a process for the hydrogenation of 1,4-butynediol to 1,4-butenediol and 1,4-butanediol using the purified 1,4-butynediol. | 2009-07-23 |
20090187051 | Process for the preparation of nitrobenzene by adiabatic nitration - This invention relates to a process for the continuous preparation of nitrobenzene. This process comprises the adiabatic nitration of benzene with a mixture of sulfuric acid and nitric acid, in which the sum of the concentrations in the reaction zone of the metal ions which form sparingly soluble metal sulfates is less than 900 mg/l, based on the volume of the aqueous phase which contains sulfuric acid. | 2009-07-23 |
20090187052 | REACTOR AND METHOD FOR REACTING AT LEAST TWO GASES IN THE PRESENCE OF A LIQUID PHASE - A reactor for reacting at least two gases in the presence of a liquid phase, provided with an external liquid phase circulation device and including at least one injector for injecting the gases and the externally circulated liquid phase. In the injector the mixing of the gases together and with the externally circulated liquid phase only begins at the outlet of the injector. | 2009-07-23 |
20090187053 | Modified ETS-10 zeolites for olefin separation - An as prepared Na-ETS-10 zeolite was modified by ion exchange with a mono-, di-, or tri-valent cation and mixtures thereof. Several of the modified ETS-10 zeolites showed improved pressure swing capacity during the selective adsorption of ethylene from an ethylene/ethane mixture, relative to Na-ETS-1 0, although the selectivity of adsorption decreased. Modification with Ba | 2009-07-23 |
20090187054 | Isomerization of Benzene-Containing Feedstocks - The benzene content in a gasoline pool is reduced by a process that hydrogenates a benzene-containing isomerization zone feedstream. The additional cyclic hydrocarbons produced by the saturation of benzene can be processed in the isomerization zone for ring opening to increase the available paraffinic feedstock or the isomerization zone can be operated to pass the cyclic hydrocarbons through to a product recovery section. The isomerization zone feedstream is treated to remove contaminants and dried before entering the hydrogenation zone. | 2009-07-23 |
20090187055 | PROCESS FOR THE PREPARATION OF STYRENE AND/OR A SUBSTITUTED STYRENE - The invention relates to a process for the preparation of styrene and/or a substituted styrene from a feed containing 1-phenylethanol and 2-phenylethanol and/or a substituted 1-phenylethanol and a substituted 2-phenylethanol, comprising a gas phase dehydration of the feed at elevated temperature in the presence of a catalyst comprising particles of alumina having a multimodal pore size distribution. | 2009-07-23 |
20090187056 | PROCESS FOR THE PREPARATION OF AN OLEFIN - Process for the preparation of an olefin comprising contacting a diluted olefinic hydrocarbon feed, containing an oxygenate feed, an olefinic co-feed and one or more diluents, with a solid zeolite catalyst to obtain a reaction product containing one or more olefins, and wherein the diluted feed is contacted with the solid zeolite catalyst at a Gas Hourly Space Velocity, as measured at standard temperature and pressure, of at least 10,000 ml diluted olefinic hydrocarbon feed/gram zeolite catalyst/hour. | 2009-07-23 |
20090187057 | PROCESS FOR THE PREPARATION OF C5 AND/OR C6 OLEFIN - Process for the preparation of C | 2009-07-23 |
20090187058 | PROCESS FOR THE PREPARATION OF AN OLEFIN - Process for the preparation of an olefin comprising a) reacting a combination of an oxygenate feed selected from the group consisting of alcohols and ethers, and an olefinic co-feed in a reactor in the presence of a one-dimensional zeolite having 10-membered ring channels to prepare an olefinic reaction mixture; b) separating the olefinic reaction mixture into at least a first olefinic product fraction and a second olefinic fraction containing olefins with 4 or more carbon atoms; and c) recycling at least part of the second olefinic fraction obtained in step b) to step a) as olefinic co-feed. | 2009-07-23 |
20090187059 | PROCESS FOR THE PREPARATION OF AN OLEFIN - Process for the preparation of ethylene and/or propylene comprising reacting an oxygenate feed and an olefinic co-feed in a reactor in the presence of a zeolite catalyst to prepare an olefinic reaction mixture; wherein the olefinic co-feed is partially obtained from an olefinic refinery stream and partially obtained from a olefinic recycle stream. | 2009-07-23 |
20090187060 | Method and Formulation for Neutralizing Toxic Chemicals and Materials - The present invention is directed to a formulation and associated method for neutralizing one or more toxic chemical and/or materials including toxic industrial chemicals and toxic industrial materials, such as irritants, heavy metals, radioactive metals, acids and acid irritants, pesticides, and various agricultural chemicals, (collectively referred to as toxic chemical, materials, or simply toxins) as well as decontaminating surfaces that have come into contact with these agents. As a result, the formulation of the present invention can be used for neutralizing a broad spectrum of toxic chemicals and materials. In one embodiment, the active ingredient comprises 2, 3, butanedione monoxime (also known as diacetyl monoxime (DAM)), and alkali salts thereof such as potassium 2,3-butanedione monoxime (KBDO). The formulation also typically includes a carrier in which the active ingredient is dispersed. In one embodiment, the carrier comprises polyethylene glycol (PEG); monomethoxypolyethylene glycol(mPEG); and combinations and derivatives thereof. | 2009-07-23 |
20090187061 | SEED MAGAZINE - The invention provides magazines for radioactive brachytherapy seeds. The seed magazines provided herein include housing, seed holder, and pusher components, and optionally have a slidable shield to protect a user from radiation. | 2009-07-23 |
20090187062 | Fixture of the Head for Transcranial Magnetic Stimulation and Transcranial Magnetic Stimulator - A transcranial magnetic stimulator according to the present invention includes fixing means for detachably fixing a magnetic field generating means and contains a fixture of a head which covers a head of an examinee to be fixed engaged with a shape of the head that is inherent to an examinee; and characterized in that: a relative position of the magnetic field generating means with respect to the head of the examinee is held constant so that the highest point of an intensity of an electric current to be induced by a magnetic field to be generated by the magnetic field generating means is constantly arranged on a target spot of a diameter not more than 10 mm, which depends on each of the examinees and is located within a cranium, by fixing the magnetic field generating means to the fixing means and a direction of a magnetic field to be generated by the magnetic field generating means and a direction of the target spot are made into a fixed relation. | 2009-07-23 |
20090187063 | INFLATABLE VENTRICULAR PARTITIONING DEVICE - This invention is directed to a device and method of using the device for partitioning a patient's heart chamber into a productive portion and a non-productive portion. The device is particularly suitable for treating patients with congestive heart failure. The device has an inflatable partitioning element which separates the productive and non-productive portions of the heart chamber and in some embodiments also has a supporting element, which may also be inflatable, extending between the inflatable partitioning element and the wall of the non-productive portion of the patient's heart chamber. The supporting element may have a non-traumatic distal end to engage the ventricular wall or a tissue penetrating anchoring element to secure the device to the patient's heart wall. | 2009-07-23 |
20090187064 | CARDIAC SLEEVE APPARATUS, SYSTEM AND METHOD OF USE - Cardiac assist sleeve and methods for using and making the cardiac assist sleeve that includes first elongate strips and second elongate strips of memory alloy that change shape to change a volume of cardiac assist sleeve. | 2009-07-23 |
20090187065 | AUTOMATIC GAIN CONTROL FOR IMPLANTED MICROPHONE - An implantable hearing instrument is provided that reduces the response to unnaturally high vibrations (e.g., due to a patient's own voice), without necessarily or substantially affecting the response to desired signals. The implantable hearing instrument system is operative to selectively alter/lower the gain of signals that have a magnitude above a predetermined threshold. Signals having unnaturally large amplitudes (e.g., due to a patient's own voice) are amplified less than desired signals, so that a patient may experience a more representative sound. | 2009-07-23 |
20090187068 | DEVICE FOR SAMPLE TAKING OR TRANSFER IN GENITAL ORGANS WITH AN IMPROVED ULTRASOUND VISIBILITY - A device whose main part is a catheter or probe which is advantageously made up by an echogenic tube on its whole length, and which is proportionally transparent. The structure is made up by a material chosen from among the group comprising amorphous thermoplastic polymer matrices incorporating a braid, strand or strip with a non metal echogenic material which is biocompatible and chosen from among filled or un-filled semi-crystalline thermoplastic polymers. | 2009-07-23 |
20090187069 | FLEXIBLE ENDOSCOPE SYSTEM AND FUNCTIONALITY - An enhanced flexibility auxiliary endoscope assembly for use with an endoscope, the assembly including at least one flexible elongate element and a flexible sleeve having a first lumen for accommodating a distal portion of an endoscope capable of assuming at least a first curvature and a second lumen for accommodating the at least one flexible elongate element, the second lumen being configured to allow the at least one flexible elongate element to assume the at least first curvature as well as at least a second curvature about the first curvature, thereby to enhance flexibility of the auxiliary endoscope assembly. | 2009-07-23 |
20090187070 | INJECTION NEEDLE FOR ENDOSCOPE, AND INNER TUBE HAVING NEEDLE BODY FIXED TO ITS DISTAL END - An injection needle for an endoscope includes an insertion portion including, an outer tube, and an inner tube movably arranged forward and backward within the outer tube, and which has a coil member and a needle body fixed to a distal portion of the inner tube, and an operating portion which is fixed to the outer tube and for operating to move the inner tube forward and backward, wherein the coil member is fitted on and is anchored to a portion opposed to a tip of the needle body, and the inner tube is fitted on and anchored to the coil member. | 2009-07-23 |
20090187071 | CAPSULE ENDOSCOPE SYSTEM AND METHOD FOR IMPLEMENTING TIME SHIFT FUNCTION THEREIN - A capsule endoscope system and related method for capturing an image of the inside of a human body using a capsule endoscope and storing or displaying the captured image in real time to implement a time shift function. The endoscopy capsule captures an image of an inside of a human body. The captured image is transmitted to an image processing unit and is displayed in real time. The image is stored in a storage unit within a predetermined storage range for the time shift function. When the time shift function is requested by a user, a progress bar is displayed, showing a progress state of the storage of the transmitted image in real time by means of an indicator. When the user moves the indicator to a past time using a user interface, a time-shifted image is displayed on the display beginning with the past time. | 2009-07-23 |
20090187072 | ENDOSCOPE AND SYSTEM AND METHOD OF OPERATION THEREOF - An endoscope including a rigid section having opposed first and second ends and an opening situated between the first and second ends, the rigid section defining a longitudinal axis; a handle portion coupled to a first end of the rigid section and having first and second scissor-type handles suitable for grasping by a user; and a base part situated at the second end of the rigid section and coupled to the first handle of the scissor-type handles such that displacement of the first handle causes a rotation of the base part. | 2009-07-23 |
20090187073 | MEDICAL DEVICE AND PROCESS OF INSTALLING MEDICAL DEVICE IN PATIENT - A medical device includes: a medical instrument introduced into a body cavity and having a contact portion that is fixed in contact with a wall within a body, and a wire; an extracorporeal device installed on a body surface and having a hole portion through which the wire can be inserted and removed, fixing mechanisms for fixing the wire inserted through the hole portion, and a housing that is fixed in contact with the body surface; and a pressure adjusting portion provided in one of the medical instrument and the extracorporeal device for maintaining a predetermined tensile force or more that is applied to the wire when the wire is fixed by the fixing mechanism with a body wall being sandwiched between the contact portion and the housing. | 2009-07-23 |
20090187074 | EPICARDIAL ACCESS AND TREATMENT SYSTEMS - Epicardial access and treatment systems are described herein where such devices may utilize multiple expanding frame members coupled to a flexible or rigid deployment catheter shaft. The multiple frame members may extend distally to collapse into a low-profile configuration and may further expand or open radially to create a working or surgical field under direct visualization and defined by the frame members and surrounding membrane while retracting any surrounding tissue. Moreover, the distal ends of each frame member may be tapered such that the frame members may close tightly relative to one another forming an atraumatic end. Any number of therapeutic tools can be passed through the catheter for performing any number of procedures on the tissue. | 2009-07-23 |
20090187075 | GUIDE WIRE ENGAGING URETEROSCOPE - This document discusses, among other things, a ureteroscope having a notch or other structure at a distal end configured to engage a guide wire and facilitate cannulation. | 2009-07-23 |
20090187076 | PIPE CONNECTION STRUCTURE IN ENDOSCOPE AND PRODUCING METHOD THEREOF - A pipe connection structure for an endoscope is provided with a pipe made of a corrosion-resistant alloy material, and a piping block made of a corrosion-resistant alloy material, the piping block having a pipe insertion hole. An end of the pipe is fitted in the pipe insertion hole and the pipe and the piping block are connected by welding by irradiating a laser beam on the entire circumference of an area where the end of the pipe is fitted in the hole formed on the piping block. An axial length of the pipe inserted in the pipe insertion hole is in a range of 0.5 to 2 times a wall thickness of the pipe. | 2009-07-23 |
20090187077 | Battery-powered light source device for endoscope - A battery-powered light source device | 2009-07-23 |
20090187078 | LIGHT SOURCE APPARATUS - The present invention relates to a light source apparatus for a laryngoscope. The light source apparatus is remotely operated. In an embodiment, it comprises a magnetically operated reed switch. A co-operating magnet in the laryngoscope blade actuates the reed switch when the blade is brought into proximity with the light source apparatus mounted in the laryngoscope handle. | 2009-07-23 |
20090187079 | SURGICAL INSTRUMENT ACCESS DEVICE - Embodiments of an access device system useful for single or limited port procedures comprises a retractor and a gel cap removably coupled to the retractor. The gel cap comprises a gel pad that acts as an artificial body wall, through which instruments may be inserted into a body cavity, either directly or through one or more trocars. The gel pad permits flexible instrument placement, as well as translational and angular degrees of freedom for the instruments while maintaining a gas tight seal. | 2009-07-23 |
20090187080 | Distraction and retraction assemblies - An assembly ( | 2009-07-23 |
20090187081 | Endonasal speculum - A short (60-70 mm) endonasal speculum for performing operations within and around the sellar region of the human head includes two side members each of which is composed of a handle and an elongated blade. The handles are attached to each other by a hinge and one of the handles includes a variable dilation control that is used to open the speculum. The elongated blades are arcuate in cross section and have distal ends that are opposed to each other in a trapezoidal configuration, either up or down, which permits greater visualization and access into the regions above and below the sella and greater instrument maneuverability within the speculum. | 2009-07-23 |
20090187082 | SYSTEMS AND METHODS FOR DIAGNOSING THE CAUSE OF TREND SHIFTS IN HOME HEALTH DATA - A system and method for determining the cause of a trend shift in physiological data received from a patient under observation includes receiving physiological data on a plurality of measured physiological parameters from the patient and performing a statistical analysis on a portion of the physiological data to determine a measured shift over a confidence interval in each of the plurality of physiological parameters. A signature shift is defined for each of the plurality of physiological parameters that is indicative of a pre-determined medical condition and the measured shift confidence interval of each of the plurality of physiological parameters is compared to these signature shifts. From this comparison between the measured shift confidence interval and the signature shift of each of the plurality of physiological parameters, a physiological assessment is formulated. | 2009-07-23 |
20090187083 | CATHETER - A catheter and associated method for taking a plurality of samples from within a length of a blood vessel. The catheter includes an elongate central body arranged to be inserted into and positioned along a central region of a blood vessel. A plurality of collection areas are defined along the elongate central body for collecting samples at the central region of the blood vessel. A plurality of mixers are provided radially outwardly of the elongate central body and arranged to create a flow of blood from a boundary layer at a wall of the blood vessel to the elongate central body. This enables the collection areas to collect samples from the boundary layer. | 2009-07-23 |
20090187084 | Flexible Carbohydrate-Bearing Polymer - A sensor for the detection or measurement of a carbohydrate analyte in fluid comprises components of a competitive binding assay the readout of which is a detectable or measurable optical signal retained by a material that permits diffusion of the analyte but not the assay components, the assay components comprising: a carbohydrate binding molecule labelled with one of a proximity based signal generating/modulating moiety pair; and a carbohydrate analogue capable of competing with the analyte for binding to the carbohydrate binding molecule, the carbohydrate analogue being a flexible water-soluble polymer comprising: polymerized or co-polymerised residues of monomer units, the monomer unit residues bearing pendant carbohydrate or carbohydrate mimetic moieties and pendant moieties which are the other of the proximity based signal generating/modulating moiety pair. | 2009-07-23 |
20090187085 | System And Method For Estimating Physiological Parameters By Deconvolving Artifacts - There is disclosed a system and methods to estimate physiological parameters. In accordance with embodiments a method is disclosed which includes generating distribution data for a plurality of signals. The method may also include deconvolving one of the plurality of signals from the other plurality of signals to produce clean signals. The clean signals may then be used to calculate physiological parameters. | 2009-07-23 |
20090187086 | Integrated White LED Illuminator and Color Sensor Detector System and Method - An improved illuminator ( | 2009-07-23 |
20090187087 | ANALYSIS OF METABOLIC GASES BY AN IMPLANTABLE CARDIAC DEVICE FOR THE ASSESSMENT OF CARDIAC OUTPUT - Analysis of metabolic gases by an implantable medical device allows the assessment of the status of a congestive heart failure patient by providing for the assessment of cardiac output. The present invention is directed to an implanted medical device configured to measure concentrations of metabolic gases in the blood to determine cardiac output of a patient. The device is also configured to measure changes in the cardiac output of a patient. The present invention is also directed to a method of measuring cardiac output by an implanted medical device. Further, the detection of changes in cardiac output utilizing an implanted medical device as disclosed herein is useful in a method of detecting exacerbation of congestive heart failure. The implanted medical device can also be used to pace a heart to modify cardiac output in a patient. | 2009-07-23 |
20090187088 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2009-07-23 |
20090187089 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2009-07-23 |
20090187090 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2009-07-23 |
20090187091 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2009-07-23 |
20090187092 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2009-07-23 |
20090187093 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2009-07-23 |
20090187094 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2009-07-23 |
20090187095 | Analyte Monitoring Device and Methods of Use - An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte. The analyte monitor may also be part of a drug delivery system to alter the level of the analyte based on the data obtained using the sensor. | 2009-07-23 |
20090187096 | Sensor Array for Nuclear Magnetic Resonance Imaging Systems and Method - The present invention generally provides improved devices, systems, and methods for measuring materials with NMR and/or MRI. Exemplary embodiments provide a sensor array for NMR mapping of the material. For example tissue can be measured with the sensor array mounted on a probe body having a distal portion which can be inserted through a minimally invasive aperture. While many tissues can be measured and/or diagnosed, one exemplary embodiment includes a probe adapted for insertion into a lumen of a blood vessel. The sensor array can provide improved spatial resolution of tissue and/or tissue structures positioned near the sensor array to diagnose potentially life threatening diseases, for example a fibrous cap covering a vulnerable plaque. In specific embodiments, the sensors are attached to an expandable member, for example a balloon, which can be inflated to urge the probe sensors radially outward to position the sensors near the tissue structures. | 2009-07-23 |