29th week of 2010 patent applcation highlights part 43 |
Patent application number | Title | Published |
20100184563 | Athletic Performance Monitoring Systems and Methods in a Team Sports Environment - Systems and methods for sensing and monitoring various athletic performance metrics, e.g., during the course of a game, a practice, a training session, training drills, and the like, are described. These systems and methods can provide useful metrics for players and coaches relating to athletic performances in various sports, including various team sports. | 2010-07-22 |
20100184564 | Athletic Performance Monitoring Systems and Methods in a Team Sports Environment - Systems and methods for sensing and monitoring various athletic performance metrics, e.g., during the course of a game, a practice, a training session, training drills, and the like, are described. These systems and methods can provide useful metrics for players and coaches relating to athletic performances in various sports, including various team sports. | 2010-07-22 |
20100184565 | Device for Optimized Exercise Training of a Diabetic - A system is disclosed for optimizing exercise training of a diabetic exerciser. Computer software accepts physical status data and, in preferred embodiments, information regarding available exercise equipment, and formulates therefrom an optimized diet and exercise program, which is downloaded to an MP3 player or similar portable electronic device. The portable device directs the exerciser during workouts, while communicating with a blood glucose monitor and preferably with a heart rate monitor so as to monitor the exerciser's blood glucose level and heart rate during exercise, and warn the exerciser if the blood glucose level exceeds specified bounds. The portable device records a log of physiological data, exercise performed, and food consumed, for later upload to the computer and possible transmission to a healthcare provider. Preferred embodiments include only software. Other embodiments include a portable device, blood glucose monitor, heart rate monitor, or communications enabler. | 2010-07-22 |
20100184566 | DEVICE FOR STRENGTHENING TONGUE MUSCLE - To provide a tongue muscle-strengthening device which can prevent or recover a poor posture that is attributed to no development of lingual adhesion in the mandible to the skull due to the decreased function of tongue muscles, stress-induced disorder that is attributed to the hyperfunction of the masticatory muscle group and tongue muscles in the cerebral cortex motor area, as well as the dysfunction and an aesthetic impairment of the mouth and which can actualize lingual adhesion. The tongue muscle-strengthening device in the invention of this application is composed of the part of maxillary teeth contact that is in contact with the maxillary teeth, the parts of dorsum of tongue and palate contact that are respectively in contact with the dorsum of tongue and palate, as well as the part of connection that connects the part of maxillary teeth contact with the parts of dorsum of tongue and palate contact. The user brings the part of palate contact into contact with the palate by inserting the part of maxillary teeth contact into the maxillary teeth, by bringing the part of dorsum of tongue contact into contact with the dorsum of tongue, by bringing the lingual apex into contact with the part of lingual apex contact, and by elevating the dorsum of tongue, and maintains the condition for a while. The elasticity of the part of connection places a sustained and strong burden on tongue muscles and strengthens tongue muscles. Furthermore, the tongue muscle-strengthening device in the invention of this application has good usability because it is an intraoral device. | 2010-07-22 |
20100184567 | Portable acrobatic trainer apparatus - One embodiment of a portable acrobatic training apparatus (I) with which to support and instruct athletes learning back handsprings having opposing flat vertical ends ( | 2010-07-22 |
20100184568 | Body-Stimulating Apparatus with an Oscillating Footplate - An apparatus for the stimulation of the body has a footplate, which is connected to two oscillation devices and that are present on a supporting plate, which each have a driven shaft. Braces are fastened on the extremities of the shafts, which are eccentric with respect to the shafts. Plates are fastened on the footplate, which are provided with slots in which the braces can be moved. The apparatus also has guiding elements fastened on the supporting plate, which can be moved in vertical guides that are formed by slots present in the plates. | 2010-07-22 |
20100184569 | PORTABLE EXERCISE DEVICE AND SYSTEM INCLUDING SAME - A portable exercise device. The portable exercise device includes a recoil assembly, a clutch assembly, an adjustable resistance assembly, a housing assembly, and a flexible cable member. The clutch assembly is coupled to the recoil assembly. The adjustable resistance assembly is coupled to the clutch assembly. The housing assembly includes a first portion and a second portion. The first portion defines and opening therethrough and surrounds the recoil assembly and the clutch assembly. The second portion is rotatably coupled to the first portion, defines a configured projection, and surrounds the adjustable resistance assembly. The flexible cable member is coupled to the recoil assembly, and extends through the opening defined by the first portion of the housing assembly. | 2010-07-22 |
20100184570 | DUMBBELL ASSEMBLY - A dumbbell assembly includes a dumbbell unit having a handgrip portion, and a support base for seating the dumbbell unit thereon. The dumbbell unit has a handgrip portion and a carrying structure disposed movably above the support base. A user can raise the carrying structure to attach the handgrip portion and hold the handgrip portion and the carrying structure for carrying the whole dumbbell assembly by one hand. | 2010-07-22 |
20100184571 | RESISTANCE ARRANGEMENT OF A WAIST-TWISTING MACHINE - A resistance arrangement of a waist-twisting machine, wherein the waist-twisting machine includes a rotating disc for the lower limb of the operator to stand thereon and swiveled under application of force, a rotating handlebar for the upper limb of the operator to hold thereon and swiveled under application of force, and a coupling mechanism for synchronically and reversely coupling the rotating disc and the rotating handlebar. Moreover, a resistance-adjustable apparatus is interposed between the bottom base and the upright rod transmission shaft. | 2010-07-22 |
20100184572 | EXERCISER FOR THE SAKE OF TRAINING THE ABDOMINAL MUSCLE GROUP - An exerciser for the sake of training the abdominal muscle group, wherein the operator may rotate on his backbone for taking a twisting exercise for his upper and lower bodies in reverse (different) direction; and wherein the exerciser includes a rotating disc mechanism for the lower limb of the operator to stand thereon and swiveled under application of force, a rotating handlebar mechanism for the upper limb of the operator to hold thereon and swiveled under application of force, and a coupling mechanism for synchronically and reversely coupling the rotating disc mechanism and the rotating handlebar mechanism. | 2010-07-22 |
20100184573 | Fitness Apparatus - An fitness apparatus is adapted for use by employing, a first shaft member, a second shaft member, at least one receptacle, and at least one substantially perpendicular extension. The first shaft member includes a longitudinal portion, a base portion, and a longitudinal sleeve portion extending from opposing ends, while the longitudinal sleeve portion is configured to receive a second shaft member. The second shaft member includes a plate member and a sub-member which extend from opposing ends, while the sub-member is configured to adapt the longitudinal sleeve portion. The at least one substantially perpendicular extension extends from the at least one receptacle. The first shaft member and the second shaft member cooperate to secure the fitness apparatus between two or more planes. | 2010-07-22 |
20100184574 | CUTTING TOOL REMOVAL AND INSTALLATION ASSIST DEVICE - A method of replacing a cutting tool in a tool magazine in a machine center includes providing a mounting frame having a pair of guide rails and a tool changing jig, pushing the tool changing jig toward the tool magazine until the tool changing jig contacts a rear positive stop, pivoting the clamp arms to an open position, cranking the lifting assembly upward until a V-shaped block assembly contacts the cutting tool, pivoting the clamp arms to a closed position, dislodging the cutting tool from the tool magazine, pulling the tool changing jig away from the tool magazine until the tool changing jig contacts a front positive stop on the mounting frame, replacing the cutting tool in the tool changing jig, and pushing the tool changing jig toward the tool magazine until the cutting tool is inserted and locked into the tool magazine. | 2010-07-22 |
20100184575 | METHODS AND SYSTEMS FOR MONITORING THE OPERATION OF A ROBOTIC ACTUATOR - A robotic tool changer and systems and methods for controlling the operation of a robotic tool changer are provided. The tool changer, methods, and systems include a robot-side component mountable to a robot arm end interface; a tool-side component adapted to engage a tool; a first slave module associated with the robot-side component and adapted to communicate with a first master module; and a second master module associated with the robot-side component and adapted to communicate with a second slave module associated with the tool. The second slave module may include a temporary power supply, for example, a battery or a capacitor, for instance, a super capacitor. Aspects of the invention are advantageous for performing high-speed robotic connections and disconnections, and for providing tool and tool changer performance information gathering. | 2010-07-22 |
20100184576 | METHOD AND APPARATUS FOR INTRODUCING OBJECTS INTO A SMOKING ARTICLE - An apparatus for introducing objects into a smoking article comprises a reservoir for providing a plurality of objects to be introduced into the smoking article, a rotatable wheel for delivering the objects to the location where the objects are to be introduced into the smoking article, a transfer chamber for transferring the objects to the rotatable wheel, the transfer chamber being arranged between the reservoir and the rotatable wheel and being designed such that the objects are aligned into a single vertically arranged layer therein, and means for moving the objects from the single layer in the transfer chamber in a direction towards or along the peripheral surface of the rotatable wheel. | 2010-07-22 |
20100184577 | APPARATUS FOR FORMING CURLS IN REINFORCING MATERIAL-ATTACHED PROFILE STRIP, METHOD FOR PRODUCING SPIRAL PIPE, AND APPARATUS FOR PRODUCING SPIRAL PIPE - In an embodiment, a long reinforcing material-attached profile strip ( | 2010-07-22 |
20100184578 | Swing Bucket Centrifuge Rotor - A centrifuge rotor includes a rotor body having a central hub and first and second bucket receiving spaces defined on diametrically opposed sides of the rotor body. A first pair of bucket supports is supported by the rotor body for pivotally supporting a swing bucket in the first bucket receiving space, and a second pair of bucket supports is supported by the rotor body for pivotally supporting a swing bucket in the second bucket receiving space. The rotor further includes reinforcing material wound around oppositely disposed ones of the first and second pairs of bucket supports. | 2010-07-22 |
20100184579 | THREE-PHASE SEPARATOR - A separator including a separator drum having a conical interior and rotatably mounted at an axial end about a vertical axis of rotation. A rotating spindle is located at either a lower or upper end of the separator drum and is configured to drive the separator drum. The rotating spindle is disposed in an oscillating manner about a hinge point. Also included is supply tube for a product to be processed and two fluid outlets. One fluid outlet is for a light phase and one fluid outlet is for a heavy phase. A solids material discharge opening is located in an area of the separator drum's largest inner circumference. Further included is a separation pan assembly. A pressure chamber is configured to be acted upon by a fluid to change a location of a separation zone between the light phase and the heavy phase. | 2010-07-22 |
20100184580 | Glass-ceramic sealant for planar solid oxide fuel cells - Glass-ceramic sealant is disclosed for planar solid oxide fuel cells. The glass-ceramic sealant includes 0 to 40 mol % of silicon oxide, 0 to 15 mol % boron oxide, 0 to 10 mol % of aluminum oxide, 0 to 40 mol % of barium oxide, 0 to 15 mol % of calcium oxide, 0 to 15 mol % of lanthanum oxide and 0 to 5 mol % of zirconium dioxide. At 0° C. to 600° C., the thermal expansion coefficient of the sealant is 8 to 10 ppm/° C. | 2010-07-22 |
20100184581 | GLASS YARNS CAPABLE OF REINFORCING ORGANIC AND/OR INORGANIC MATERIALS - The invention relates to a glass yarn capable of being obtained by a method consisting of mechanically drawing molten glass threads flowing from orifices disposed at the base of a die, of which the chemical composition is substantially free from boron oxide and comprises the following constituents within the limits defined hereinafter expressed in percentages by weight: | 2010-07-22 |
20100184582 | MIXED POWDER AND SINTERED BODY, MIXED CERMET POWDER AND CERMET, AND FABRICATION METHODS THEREOF - A mixed powder and a sintered body obtained by sintering the mixed powder. The mixed powder includes a solid-solution powder with complete solid-solution phase. The solid-solution powder includes a carbide or a carbonitride of at least two metals selected, including Ti, from metals of Groups IVa, Va and VIa of the periodic table, or a mixture thereof. A mixed cermet powder and a cermet obtained by sintering the mixed cermet powder are also disclosed. The mixed cermet powder includes at least a cermet powder with complete solid-solution phase. The cermet powder includes a carbide or a carbonitride of at least two metals selected, including Ti, from metals of Groups IVa, Va and VIa of the periodic table, or a mixture thereof, and at least one metal selected from the group consisting of Ni, Co and Fe. Also disclosed are a sintered body and a fabrication method of a cermet. | 2010-07-22 |
20100184583 | DENSE BORON CARBIDE CERAMIC AND PROCESS FOR PRODUCING THE SAME - An aspect of the present invention is to provide an economical production technology for obtaining a dense boron carbide ceramic product without impairment to excellent mechanical properties, which boron carbide ceramics are inherently equipped with, by conducting heating under normal pressure without application of pressure and without needing addition of a large amount of a sintering additive to a raw material or needing any special additive or treatment. The present invention provides a production process in which, upon heating a boron carbide green body under normal pressure without application of pressure after pressing a boron carbide powder material to obtain the boron carbide green body, the boron carbide green body is heated with one of a powder, green body or sintered body, which contains at least one of aluminum and silicon, being disposed in a furnace. | 2010-07-22 |
20100184584 | UNSHAPED REFRACTORY MATERIAL, A PROCESS FOR PRODUCING AN EARTH-MOIST, UNSHAPED REFRACTORY MATERIAL, AND USE OF THE UNSHAPED REFRACTORY MATERIAL - The invention relates to an unshaped refractory material, to a process for producing an earth-moist, unshaped refractory material, and also to the use of the unshaped refractory material. | 2010-07-22 |
20100184585 | Triboceramic Compound - The present invention relates to the machine buiding industry and it is used for coating of friction surfaces by triboceramics to decrease wear and to reduce the friction coefficient. The triboceramic compound contains oxides—magnesium oxide MgO, silica SiO | 2010-07-22 |
20100184586 | METAL CATALYST AND METHOD FOR PRODUCTION THEREOF - The present invention relates to a metal catalyst containing fine metal particles, characterized in that the fine metal particles have a particle diameter of 3 nm or less and also have a proportion of metallic bond state of 40% or more, which is ascribed by subjecting to waveform separation of a binding energy peak peculiar to the metal as measured by using an X-ray photoelectron spectrometer. The fine metal particles are preferably fine platinum particles. The fine metal particles are preferably supported on the surface of carrier particles by reducing ions of metal to be deposited through the action of a reducing agent in a reaction system of a liquid phase containing the carrier particles dispersed therein, thereby to deposit the metal on the surface of carrier particles in the form of fine particles. The proportion of metallic bond state of the fine metal particles is adjusted within the above range by reducing after deposition thereby to decrease the oxidation state. | 2010-07-22 |
20100184587 | PALLADIUM-GOLD CATALYST SYNTHESIS - A supported palladium-gold catalyst is produced under mild conditions using a commonly available base, such as sodium hydroxide (NaOH) or sodium carbonate (Na | 2010-07-22 |
20100184588 | METHODS OF MAKING CATALYTIC MATERIALS BY DISPERSION OF NANOPARTICLES ONTO SUPPORT STRUCTURES - Methods are disclosed herein for improving efficient catalyst utilization in processes including thermal catalysis using dry nanoparticle promoters, rather than salts of metal promoters in liquid form. Using selected process steps, the nanoparticles are more controllably dispersed on primary support particles, for effective use on secondary supports when it desired to bring reactants into contact with the secondary support. Applications that generally make use of these catalysts can be but are not limited to: emission abatement catalysts, generation of syngas, generation of liquid fuels from syngas, safety systems (hydrogen recombination catalysts in nuclear power plants) and many industrial processes. | 2010-07-22 |
20100184589 | HONEYCOMB CATALYTIC ARTICLE - There is provided a honeycomb structure where a catalyst is loaded on surfaces of inner pores of the surface layer and on a surface of the surface layer; a relation between a catalyst area proportion A of the catalyst to a gap area proportion B of a gap in a cross-section of the surface layer on the inlet side is 1% | 2010-07-22 |
20100184590 | HONEYCOMB BODY HAVING A METALLIC FOIL WITH AN OXIDE COAT, FOIL HAVING AN OXIDE COAT AND METHOD FOR PRODUCING AN OXIDE COAT ON A METALLIC FOIL - A honeycomb body, in particular a catalyst carrier body, includes metallic foil of high-temperature corrosion-resistant steel with connecting points and an oxide layer with a thickness of 60 to 80 or 70 to 75 nm on each surface. The foil is composed of steel with chromium and aluminum components, particularly 1 to 5% aluminum. The oxide layer is substantially aluminum oxide or γ-aluminum oxide with a uniform thickness having a tolerance of less than 10% or less than 5% on all surfaces. The oxide layer may be on a rolled foil having a mean surface roughness of greater than 0.3 or 0.5 μm or approximately 0.6 μm in rolling direction and/or transversely thereto. The honeycomb body is durable under high loads and has defined connecting points. A foil having an oxide coat and a method for producing an oxide coat on a metallic foil are also provided. | 2010-07-22 |
20100184591 | METHOD OF PREPARING HETEROPOLY ACID CATALYST - The present invention relates to a method of preparing a heteropoly acid catalyst used for the production of methacrylic acid by gas phase oxidation of methacrolein, more precisely a method of preparing a heteropoly acid catalyst comprising the steps of preparing a slurry by adding metal precursors and ammonium salt to protonic acid Keggin-type heteropoly acid aqueous solution and stirring thereof; and drying, molding and firing the slurry to give a catalyst. The present invention provides a method of preparing a heteropoly acid catalyst exhibiting high methacrolein conversion rate and methacrylic acid selectivity without pre-firing process by using high purity protonic acid Keggin-type heteropoly acid and ammonium salt. | 2010-07-22 |
20100184592 | PARTICLES OR COATING FOR SPLITTING WATER - The aim of the invention is to provide particles or coatings for splitting water, which are largely protected from corrosive damage. To this end, the particles or the coating consist(s) of a nucleus or a sub-layer and a shell or top layer,
| 2010-07-22 |
20100184593 | METHOD TO ACTIVATE A CATALYST FOR A CONTINUOUS PROCESS FOR THE PREPARATION OF PHENOL FROM BENZENE IN A FIXED BED REACTOR - A process to activate a titanium silicalite catalyst for the oxidation of benzene to phenol is provided. The catalyst is activated in the reactor for the oxidation by feeding to a reactor containing the titanium silicalite catalyst, during a time of from 2 to 6 hours, at a temperature ranging from 20 to 120° C., an aqueous solution of ammonium acid fluoride in a concentration ranging from 0.1% to 1% by weight; and hydrogen peroxide in a concentration ranging from 3% to 10% by weight; feeding water to the reactor at the end of the reaction; and drying or calcining the catalyst contained in the reactor to obtain the activated catalyst. The catalyst is represented by the formula: | 2010-07-22 |
20100184594 | Water-Absorbing Polymeric Particles and Method for the Production Thereof - The present invention relates to a water absorbing material obtainable by a process comprising the steps of bringing particles of a non surface-crosslinked water-absorbing polymer in contact with
| 2010-07-22 |
20100184595 | TRANSITION METAL COMPLEX ANION-BASED HYDROGEN STORAGE MATERIAL SYSTEM - An exemplary embodiment and associated method of use discloses a hydrogen storage system that liberates hydrogen and includes a combination of at least one complex hydride containing a cation and a complex hydride anion based on boron, aluminum or nitrogen, together with an approximately stoichiometric or chemically equivalent amount of at least one other complex hydride containing a cation and a complex hydride anion based on a transition metal. | 2010-07-22 |
20100184596 | METHOD FOR THE CONTROL OF WEEDS IN TURF - The present invention relates to a method for controlling weeds in turfgrass, which comprises applying to the turfgrass, the locus thereof or seeds thereof a herbicidally effective amount of 4-Hydroxy-3-[2-(2-methoxyethoxymethyl)-6-trifluoromethylpyridine-3-carbonyl]-bicyclo[3.2.1]oct-3-en-2-one or a composition which contains said compound. | 2010-07-22 |
20100184597 | Method for producing transgenic plants resistant to weed control compounds which disrupt the porphyrin pathways of plants - A method for producing a transgenic plant which is resistant to a weed control compound is disclosed. In the inventive method, a nucleotide sequence encoding a variant of plant protoporphyrinogen IX oxidase that lacks the FAD binding sequence is introduced into a plant cell. The nucleotide sequence is expressed and the plant cell is regenerated into a transgenic plant. | 2010-07-22 |
20100184598 | 4-AZA INDOLE DERIVATIVES AND THEIR USE AS FUNGICIDES - The present invention relates to a method of preventing and/or controlling fungal infection in plants and/or plant propagation material comprising applying to the plant or plant propagation material a fungicidally effective amount of a compound of formula (I) or a salt of N-oxide thereof. In addition, the present invention also relates to a compound of formula (I). | 2010-07-22 |
20100184599 | HERBICIDE COMPOSITION COMPRISING HERBICIDE COMPOUND IN ACID FORM AND ACIDIFYING AGENT - Described are herbicide compositions and methods for their preparation and use, in particular, herbicide compositions and methods relating to herbicide compositions containing herbicide compounds in acid form, and further including an acidifying agent. | 2010-07-22 |
20100184600 | Stable Ethylene Inhibiting Compounds and Methods for Their Preparation - A method to inhibit the ethylene response in plants with cyclopropene compounds by first generating stable cyclopropane precursor compounds and then converting these compounds to the gaseous cyclopropene antagonist compound by use of a reducing or nucleophilic agent. | 2010-07-22 |
20100184601 | Method and Means Relating to Multiple Herbicide Resistance in Plants - Methods for overcoming multiple herbicide resistance (MHR) in plants using inhibitors of GST suppression of Formula (I), novel chemical inhibitors of Formula (Ia), compositions comprising compounds of Formula (I), and uses and methods relating thereto. | 2010-07-22 |
20100184602 | HERBICIDALLY AND INSECTICIDALLY ACTIVE PHENYL-SUBSTITUTED PYRIDAZINONES - The invention describes phenyl-substituted pyridazinones of the formula (I) as herbicides and insecticides. | 2010-07-22 |
20100184603 | Alcohol alkoxylates, compositions containing these, and use of the alcohol alkoxylates as adjuvants for the agrochemical field - The present invention relates to certain alcohol alkoxylates of the amphiphilic type, to agrochemical compositions comprising them, and to the use of the alcohol alkoxylates as activity-enhancing adjuvant in the agrochemical sector and in particular in the sector of plant protection. The alcohol alkoxylates are alkoxylated alcohols of the formula (I) | 2010-07-22 |
20100184604 | SUPERCONDUCTING ELEMENT JOINT, A PROCESS FOR PROVIDING A SUPERCONDUCTING ELEMENT JOINT AND A SUPERCONDUCTING CABLE SYSTEM - The invention relates to a superconducting element joint comprising a joint between two superconducting elements comprising at least one direct SC-SC transition joint. By the invention an improved superconducting element joint may be obtained. | 2010-07-22 |
20100184605 | PLANT FARNESYLTRANSFERASES - This invention relates to an isolated nucleic acid fragment encoding a farnesyltransferase subunit. The invention also relates to the construction of a chimeric gene encoding all or a portion of the farnesyltransferase subunit, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the farnesyltransferase subunit in a transformed host cell. | 2010-07-22 |
20100184606 | Methods For Selective Targeting - A selective targeting method is disclosed which comprises contacting a peptide library with an anti-target to allow the peptides to bind; separating non-binding peptides from the anti-target bound peptides, contacting the non-binding anti-target peptides with a target allowing the unbound peptides to bind with the target to form a target-bound peptide complex; separating the target-bound peptide complex from peptides which do not bind to the target, and identifying the target-bound peptides. In one embodiment the target is skin or hair. In another embodiment the anti-target is hair when the target is skin, and the anti-target is skin when the target is hair. | 2010-07-22 |
20100184607 | MONOSACCHARIDE COMPOUNDS AND METHODS THEREFOR - A monosaccharide compound of formula I as shown in the specification. Processes for the preparation of the compound of formula I and methods of screening for antibacterial or antibiotic compounds involving the compound of formula I. | 2010-07-22 |
20100184608 | REFERENCE GENES FOR THE NORMALIZATION OF GENE EXPRESSION ANALYSIS DATA - The present invention relates to reference genes, primers, and probes for the normalization of gene expression analysis data from blood samples of a patient. The invention further relates to a method for the normalization of gene expression analysis data with the aid of reference genes, primers, or probes. | 2010-07-22 |
20100184609 | USE OF A TERNARY MATRIX AS AN ADAPTER FOR MOLECULAR BIOLOGICAL INFORMATION, AND A METHOD TO SEARCH AND TO VISUALIZE MOLECULAR BIOLOGICAL INFORMATION STORED IN AT LEAST ONE DATABASE - It is proposed by the present invention the use of ternary matrices as an adapter of molecular biological information for integration of the said biological information. Another exclusive aspect of the present invention consists in a method of search and visualization of molecular biological information stored in at least one database, wherein a preferred implementation of the method is made using a computer program and wherein the same may be accessed using a computer network such as the Internet. | 2010-07-22 |
20100184610 | METHOD OF PROGNOSIS - Provided are methods, kits and arrays for use in determining susceptibility to keloid formation. These determine susceptibility based on comparison of gene expression in a patient of interest with expression in a control sample. If expression of at least one gene, selected from the group of genes set out in Table 1, is decreased in a sample representative of gene expression in the patient compared to expression of the same gene (or genes) in the control sample this is indicative of a susceptibility to keloid formation. | 2010-07-22 |
20100184611 | ENCODED SELF-ASSEMBLING CHEMICAL LIBRARIES (ESACHEL) - The invention concerns a chemical compound comprising a chemical moiety (p) capable of performing a binding interaction with a target molecule (e.g. a biological target) and further comprising an oligonucleotide (b) or functional analogue thereof. In a first embodiment according to the invention, the chemical compound is characterized in that the oligonucleotide (b) or functional analogue comprises at least one self-assembly sequence (b | 2010-07-22 |
20100184612 | NOVEL TRIPLE TAG SEQUENCE AND METHODS OF USE THEREOF - The present disclosure relates to novel triple tag sequences that may comprise a 6× histidine tag, a c-myc tag and a V5 tag. The present disclosure also provides polynucleotides, proteins, vectors and host cells that comprise the triple tag sequence of the present disclosure, including libraries of such polynucleotides, proteins, vectors and host cells. The novel triple tag sequences of the present disclosure may be used in phage display vectors and phage libraries and in methods for detection, screening, capture, purification, quantitation, and/or recovery of proteins of interest to which they are linked. Proteins of interest include antibodies such as single chain antibodies, single chain antibodies, and Fab fragments of antibodies or peptides such as non-antibody peptides. | 2010-07-22 |
20100184613 | Proteome Epitope Tags and Methods of Use Thereof in Protein Modification Analysis - Disclosed are methods for reliably detecting the presence of proteins, including proteins with various post-translational modifications (phosphorylation, glycosylation, methylation, acetylation, etc.) in a sample by the use of one or more capture agents that recognize and interact with recognition sequences uniquely characteristic of a protein or a set of proteins (Proteome Epitope Tags, or PETs) in the sample. Arrays comprising these capture agents or PETs are also provided. | 2010-07-22 |
20100184614 | MICROARRAY SYSTEMS AND METHODS FOR IDENTIFYING DNA-BINDING PROTEINS - Disclosed are methods for identifying double-stranded nucleic acid protein binding sites and double-stranded nucleic acid binding proteins. The method can include contacting a sample with at least one partially double-stranded nucleic acid probe under conditions that permit binding of double-stranded binding proteins and partially double-stranded nucleic acid probes. In particular examples, the partially double-stranded nucleic acid probes include a first portion of single-stranded nucleic acid at least about 15 nucleotides in length with a unique index sequence and a second portion of double-stranded nucleic acid greater than about 8 base pairs in length with a potential binding site for a double-stranded nucleic acid binding protein. The protein bound partially double-stranded nucleic acid probe can then be isolated and detected by hybridization to a nucleic acid indexing probe. Also disclosed are kits and devices for carrying out the methods. | 2010-07-22 |
20100184615 | Display of Binding Agents - The present invention relates to a method of preparing a genetic package displaying oligomers of modular antibody domains binding to a target and to a scaffold ligand as well as to vectors and libraries of genetic packages produced thereby. The invention further relates to methods of selecting suitable linker sequences for use in such oligomer display. | 2010-07-22 |
20100184616 | SPATIALLY CONTROLLED ILLUMINATION OF BIOLOGICAL SAMPLE ARRAY THROUGH WEDGE-SHAPED SUPPORT - Two-dimensional samples or sample arrays such as electrophoresis gels and microplates, containing fluorescently labeled species, are illuminated by an illumination device that includes a slab of non-autofluorescing or low-autofluorescing material shaped to receive excitation light from one or more edges and to distribute the light to emerge from an upper surface of the slab at a uniform intensity along the length and width of the upper surface. | 2010-07-22 |
20100184617 | CHARACTERIZATION OF MICROARRAYS BY NANOGOLD STAINING - Methods for determining the quality of a biomolecular microarray to determine suitability of the microarray for performing specific binding reactions, such as hybridization, are provided. Methods are based on staining a microarray with a solution of detectable nanoparticles that reversibly stain the biomolecules through an electrostatic interaction to select microarrays that meet quality standards for hybridization reactions. A gold nanoparticle solution based staining method for DNA microarrays is provided. Destaining methods allowing multiple rounds of hybridization of nanogold stained microarrays are provided. Microarrays selected by methods of the invention are provided. | 2010-07-22 |
20100184618 | DNA LIGATION ON RNA TEMPLATE - Disclosed are methods and compositions for detection and amplification of nucleic acids, wherein two DNA strands hybridized to an RNA strand are ligated. In one aspect, the disclosed methods include removal of an energy source, such as ATP, upon charging a ligase to form an enzyme-AMP intermediate, and then adding substrate, which results in one complete round of RNA-templated DNA ligation. In another aspect, the ligation reaction is accomplished by use of a mixture of at least two different ligase enzymes. The disclosed methods and compositions for RNA-templated DNA ligation may be particularly useful for detection of RNA sequence variants, for example RNA splice variants, and for quantitative expression analysis. | 2010-07-22 |
20100184619 | METHOD FOR ANALYZING ORGANELLE-LOCALIZED PROTEIN AND MATERIAL FOR ANALYSIS - A method for analyzing an organelle-localized protein, which enables one to determine whether or not a test protein localizes to an organelle, comprising the steps of: (a) a step of introducing a fusion peptide (a), which comprises one half-peptide of an intein, one half-peptide of a fluorescent protein and an organelle-targeting signal peptide, into a eukaryotic cell; (b) a step of introducing a test protein bound to a fusion peptide (b), which comprises the other half-peptide of the fluorescent protein and the other half-peptide of the intein, into the eukaryotic cell; and (c) a step of detecting fluorescence signal emitted by the fluorescent protein, and a material for analysis to be used in such method are provided. | 2010-07-22 |
20100184620 | METHOD OF BIOLOGICAL AND MEDICAL DIAGNOSTICS USING IMMUNE PATTERNS OBTAINED WITH ARRAYS OF PEPTIDE PROBES - Immune-chips, which are arrays of peptides probes are used to obtain a pattern which characterizes the global immune reactivity status of the human or other organism, are described. The peptide probes participate in immune reactions with antibodies and immune receptors of the investigated organisms to generate an immune pattern on the chip, which are detected and stored as patterns in databases. The patterns are then compared with other patterns observed with the same array and obtained under physiological, pathological and experimental conditions from the same or other organisms. The comparison is used to classify the state of the investigated organisms based on similarity to other observed states. The immune chips and the obtained patterns can be used for clinical diagnosis and biological studies, such as the investigation of similarities between physiological, pathological or experimental processes. | 2010-07-22 |
20100184621 | METHOD AND DEVICE FOR FORMING BIOLOGIC CELL AGGREGATES - The invention relates to a method for cultivating biologic cells ( | 2010-07-22 |
20100184622 | SUBSTRATE FOR BIOCHIP AND BIOCHIP - A substrate for biochips with which immobilization is easy, which does not exhibit self-fluorescence, which is easy to manufacture, and which is excellent in flatness and surface precision, is disclosed. A substrate having a substrate body of the biochip, which is made of a metal, and a carbon layer having functional groups formed on the metal substrate body is used as a substrate for biochips. Since the substrate body of the substrate for biochips is made of a metal, the substrate is not only easy to manufacture, but also free from cracking and chipping, so that it allows easy handling, and high flatness and surface precision can be attained. Therefore, the problem that the optical system is hard to focus when detecting fluorescence does not occur. Moreover, since the substrate body is made of a metal, it does not emit fluorescence by itself. In addition, since the carbon layer has functional groups such as amino groups, biologically relevant substances can be easily immobilized. | 2010-07-22 |
20100184623 | GENE-ARRAY OPERATION CHIP DEVICE - A gene-array operation chip device includes a reaction chamber, and a plurality of inlet holes connected respectively to agitation channels for creating agitation currents within the reaction chamber. Each agitation channel has two ends respectively connected to one of the inlet holes and to the reaction chamber. The agitation channels are inclined with respect to radial directions about an axis of the reaction chamber. Preferably, a flow channel interconnecting two reaction chambers has a hydrophobic wall surface to limit a fluid from flowing naturally between the chambers. In an embodiment, the reaction chamber is a hybridization chamber provided with a membrane-array. | 2010-07-22 |
20100184624 | ARRAYS AND METHODS COMPRISING M. SMITHII GENE PRODUCTS - The present invention encompasses arrays and methods related to the genome of | 2010-07-22 |
20100184625 | Biomarkers for Inflammatory Bowel Disease and Irritable Bowel Syndrome - The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome. | 2010-07-22 |
20100184626 | ARRAYS OF BIOLOGICAL MEMBRANES AND METHODS AND USE THEREOF - The present invention overcomes the problems and disadvantages associated with prior art arrays by providing an array comprising a plurality of biological membrane microspots associated with a surface of a substrate that can be produced, used and stored, not in an aqueous environment, but in an environment exposed to air under ambient or controlled humidities. Preferably, the biological membrane microspots comprise a membrane bound protein. Most preferably, the membrane bound protein is a G-protein coupled receptor, an ion channel, a receptor serine/threonine kinase or a receptor tyrosine kinase. | 2010-07-22 |
20100184627 | OLIGONUCLEOTIDE MEDIATED NUCLEIC ACID RECOMBINATION - Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided. | 2010-07-22 |
20100184628 | BIS-SULFHYDRYL MACROCYCLIZATION SYSTEMS - The present invention provides novel peptidomimetic macrocycles and methods for their preparation and use, as well as amino acid analogs and macrocycle-forming linkers, and kits useful in their production. | 2010-07-22 |
20100184629 | CELL TRAY SYSTEMS AND METHODS - A method and system for describing a cell tray are described. The method and system includes providing a first layer and a second layer. The first layer is of an optically transparent substrate material. The second layer is on top of the first layer, the second layer includes a plurality of cell wells, each of the plurality of cell wells being formed by penetrating the second layer to a preselected depth. | 2010-07-22 |
20100184630 | BREAKING THE RHEOLOGY OF A WELLBORE FLUID BY CREATING PHASE SEPARATION - Embodiments of this invention relate to compositions and methods of treating a subterranean formation penetrated by a well bore including introducing a Theological polymer into a subterranean formation, introducing a partitioning agent into a subterranean formation and forming a heterogeneous mixture comprising a dispersed Theological polymer-rich phase and a partitioning agent-rich phase, wherein the viscosity of the mixture is lower than the viscosity of the mixture when no partitioning agent is present. Embodiments of this invention relate to compositions and methods of treating a surface in contact with a wellbore and/or a subterranean formation penetrated by a well bore including forming a heterogeneous mixture comprising a dispersed Theological polymer-rich phase and a partitioning agent-rich phase at the surface of the subterranean formation, and introducing the mixture into a subterranean formation, wherein the viscosity of the mixture within the subterranean formation is lower than the viscosity of the mixture when no partitioning agent is present and wherein the viscosity of the mixture within the subterranean formation is lower than the viscosity of the mixture when the mixture is formed at the surface of the subterranean formation. | 2010-07-22 |
20100184631 | PROVISION OF VISCOUS COMPOSITIONS BELOW GROUND - A method of providing a viscous emulsion at a subterranean location accessible via a wellbore, begins by providing an aqueous/aqueous emulsion comprising two aqueous solutions which, at surface temperature and pressure, are able to co-exist as separate aqueous phases in contact with each other. The two phases contain respective solutes which are sufficiently incompatible that they cause phase separation. The dispersed phase is rich in one solute, which may be a thickening polymer, while continuous phase is rich in a second solute, which may comprise surfactant. A hydrophobic liquid is dispersed in this emulsion to become the dispersed phase of a viscous emulsion whose continuous phase is provided by the aqueous/aqueous emulsion. The hydrophobic liquid and the aqueous/aqueous emulsion may be pumped separately down the wellbore to the subterranean location, and allowed to mix there so as to form the viscous emulsion at the subterranean location. On mixing, surfactant from the aqueous/aqueous emulsion may migrate to the oil/water interface, allowing the aqueous phases to become one phase with the result that the emulsion is further thickened by any thickening polymer in its composition. Even more thickening can be achieved by crosslinking the thickening polymer. | 2010-07-22 |
20100184632 | Automatic or Machine Dishwashing Compositions of Sulfonated Estolides and Other Derivatives of Fatty Acids and Uses Thereof - Sulfo-estolides and methods of making them are described. Useful methods include acid side bleaching, partial hydrogenation of the fatty acid, pretreatment of the fatty acid to provide color inhibition, acid side hydrolysis of the sulfo-estolides, or conversion of SHP to an essentially fully hydrolyzed product (HSHP) or a partially hydrolyzed product (PHSHP). Formulations and concentrated formulations of automatic dishwasher detergent or machine wash detergent compositions containing sulfo-estolides, among others, are also included. | 2010-07-22 |
20100184633 | Light Duty Liquid Detergent Compositions of Sulfonated Estolides and Other Derivatives of Fatty Acids and Uses Thereof - Light duty liquid detergent formulations that contain sulfo-estolide surfactants, sulfo-estolide derivatives and salts of sulfo-estolides are disclosed. The compositions of the presently described technology are useful for soil removal applications including, but not limited to, washing dishes by hand. | 2010-07-22 |
20100184634 | Process For Preparing Fabric Softener Compositions - A process is disclosed for preparing a fabric softener composition containing a quaternary ammonium salt, and a silicone or organic oil. The process involves forming a thick phase aqueous dispersion of the quaternary ammonium salt with the silicone or organic oil, and further admixing additional water to form a fabric softener composition. | 2010-07-22 |
20100184635 | COMPOSITION AND METHOD - A structured composition contains an organic phase containing a fragrance composition, wherein the organic phase is structured by a structuring polymer which contains fatty acid dimer/trimer containing moieties and urea and/or urethane linkages. The structured composition is particularly suitable for use as an air freshener or candle. | 2010-07-22 |
20100184636 | Method of Regulating Mammalian Target-of-Rapamycin Activity by Interaction Between Phospholipase D and Raptor - The present invention relates to a method of regulating mammalian target-of-rapamycin (mTOR) by regulating a phospholipase D (PLD) activity that generates a complex with mTOR. Further, the present invention also relates to a method of screening inhibitors of mTOR, and a method and a composition for treating mTOR-related metabolic diseases by inhibiting mTOR. | 2010-07-22 |
20100184637 | PHARMACEUTICAL AND/OR COSMETIC COMPOSITION CONTAINING AN ACTIVE ANTIOXYDANT PRINCIPLE AND CELL ENERGY ACTIVATOR - A cosmetic or pharmaceutical composition, and particularly dermatological composition, comprising, in a physiologically adapted medium, as active principle, polypeptides or peptides, and methods of administering a composition capable of increasing cell energy and to protect the skin from oxidative damage. Also, a cosmetic treatment procedure aimed at protecting the skin and the skin appendages from external aggressions and to combat skin aging. | 2010-07-22 |
20100184638 | Galanin Receptors and Brain Injury - There is provided the use of a GALR2-specific agonist in the preparation of a medicament for the prevention or treatment of brain injury, damage or disease, wherein the brain injury or damage is caused by one of: embolic, thrombotic or haem-orrhagic stroke; direct or indirect trauma or surgery to the brain or spinal cord; ischaemic or embolic damage to the brain during cardiopulmonary bypass surgery or renai dialysis; reperfusion brain damage following myocardial infarction; brain disease; chemical damage as the result of excess alcohol consumption or administration of chemotherapy agents for cancer treatment; radiation damage; or immunological damage as the result of bacterial or virai infection. The brain disease may be one of Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis or variant Creutzfeld Jacob Disease. | 2010-07-22 |
20100184639 | NUCLEIC ACIDS AND POLYPEPTIDES SPECIFIC OF THE NEISSERIA GENUS PATHOGENIC STRAINS - The invention concerns nucleic acids coding for polypeptides specific of the | 2010-07-22 |
20100184640 | DOG DIABETES - A method a method for diagnosing susceptibility to diabetes in a non-human animal, the method comprising: a) identifying whether or not a polymorphism as defined in Table 4 or a polymorphism which is in linkage disequilibrium with such a polymorphism is present in the genome of the animal; and b) thereby diagnosing whether the animal is susceptible to diabetes, wherein optionally the said identifying is carried out on a sample from the animal. | 2010-07-22 |
20100184641 | Novel Plasma Protein Affinity Tags - Method for increasing half-life of therapeutic agents in plasma and novel polypeptide derivatives. | 2010-07-22 |
20100184642 | Transgenic Plants Expressing Cobalamin Binding Proteins - The present invention relates to the use of transgenic plants for the expression of vitamin B12 (cobalamin) binding proteins. Plant cells are transformed with nucleotide sequences adapted for expression and secretion of vitamin B12 binding proteins. The present invention also relates to the use of recombinant vitamin B12 binding proteins from plants in analytical tests and treatment of vitamin B12 deficiency. Also disclosed is a method for purification of recombinant vitamin B12 binding proteins. | 2010-07-22 |
20100184643 | Methods and Compounds Regulating the Erythroid Response to Iron Deficiency - The present invention discloses the signaling pathway involved in erythroid repression by iron deficiency. Further disclosed is a non-toxic small-molecule compound which potently reverses the erythroid repression caused by iron deficiency. The present invention further encompasses novel compounds for inhibition of red cell production, useful, for example, in the treatment of polycythemia vera, a malignancy causing uncontrolled red cell production. These inhibitory compounds also promote megakary-ocytic lineage commitment and may therefore be useful for augmentation of platelet production. The present invention further discloses isocitrate reversal of iron deprivation. | 2010-07-22 |
20100184644 | MUCOSAL REPAIR BY TFF DIMER PEPTIDES - The present invention relates to the use of trefoil factor 1 (TFF1) and trefoil factor 3 (TFF3) dimers and a pharmaceutical composition comprising TFF dimers for increasing the viscosity of mucin in mucus layers and the repair of damaged mucus layers in the gastrointestinal tract (mouth, oesophagus, stomach, small and large intestine, colon) the respiratory passages, the eye, the urinary system (including the bladder) and the cervis uteri. | 2010-07-22 |
20100184645 | STITCHED POLYPEPTIDES - The present invention provides inventive stitched polypeptides, pharmaceutical compositions thereof, and methods of making and using inventive stitched polypeptides. | 2010-07-22 |
20100184646 | MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN - The present invention relates to peptide ligands of the melanocortin receptors, in particular the melancortin-4 receptor, and as such, are useful in the treatment of disorders responsive to the activation of this receptor, such as obesity, diabetes mellitus and sexual dysfunction. | 2010-07-22 |
20100184647 | Use of Epinecidin-1 Peptides and Anti-lipopolysaccharide Factor Peptides for Treating Microbial Infection - Treatments of trichomonas, propionibacterium, or yeast infection using an epinecidin-1 peptide or an anti-lipopolysaccharide factor peptide. | 2010-07-22 |
20100184648 | Therapeutic agent for non-alcoholic fatty liver disease, and screening method for drug candidate compound for treatment or prevention of non-alcoholic fatty liver disease - A therapeutic agent for a non-alcoholic fatty liver disease comprising a melanin-concentrating hormone receptor antagonist as an active ingredient, which is developed based on a novel mechanism of action that a melanin-concentrating hormone receptor is involved in non-alcoholic fatty liver diseases. A method for screening a drug candidate compound for the treatment or prevention of a non-alcoholic fatty liver disease by utilizing the mechanism. | 2010-07-22 |
20100184649 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS - The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against | 2010-07-22 |
20100184650 | Treating post-seizure patients - Patients are subject to a post-seizure treatment regime to separately inhibitor consecutive targets of an epileptogenic cascade comprising neurotransmitter receptor signaling, kinase/phosphatase activity, protein translation, and apoptosis or inflammation. | 2010-07-22 |
20100184651 | TARGETED FUSION PROTEINS FOR CANCER THERAPY - The invention relates to fusion proteins useful as therapeutics against cancer. The fusion protein comprises of cell-targeting moiety and apoptosis-inducing moiety. Cell-targeting moiety and apoptosis-inducing moiety are linked by a flexible linker, which are specifically recognized by cancer specific protease and cleaved in situ to release the apoptotic domain. In particular, the invention is illustrated by a recombinant fusion protein between human Vasoactive Intestinal Peptide (VIP) and BH3 domain of Bcl2 family protein, linked by a linker that has site for cancer specific proteases. The fusion protein specifically targets VIP receptor over-expressing cancer cells and induces cell-specific apoptosis after cleavage at the linker site by cancer specific proteases. Such fusion proteins are useful for the delivery of therapeutic/apoptotic moiety (peptides) to specific cells with perturbed expression of, but not limited to neuropeptide receptors. | 2010-07-22 |
20100184652 | PEPTIDE INHIBITORS OF ABL KINASES - Provided are purified compounds comprising SEQ ID NO:1, where the tyrosine at residue (10) is phosphorylated. Also provided are purified compounds comprising SEQ ID NO:1, where the amino acid sequence of the compound is less than 400 amino acids. Additionally provided are methods of determining whether an agent is a candidate inhibitor of an Abl kinase. Further provided are methods of inhibiting an Abl kinase. Also provided are methods of treating a patient having a condition characterized by a mutant AbI kinase. Additionally provided are methods of treating a patient at risk for a condition characterized by a mutant AbI kinase. Methods of labeling an AbI kinase are also provided. Additionally, methods of isolating an Abl kinase from a tissue are provided. | 2010-07-22 |
20100184653 | Derivates of Polyethylene Glycol Modified Thymosin Alpha 1 - Pharmaceutical compositions that include thymosin alpha 1 peptide derivatives modified at the C-terminal of the peptide chain with polyethylene glycol, and their pharmaceutical acceptable salts, are generally disclosed. Also, new methods used to prepare these thymosin alpha 1 peptide derivatives modified at the C-terminal of the peptide chain with polyethylene glycol are generally provided. The presently disclosed compounds and their salts can be prepared administered to humans to treat immune disease and can also be used in adjuvant treatment. | 2010-07-22 |
20100184654 | ANTI-MICROBIAL TARGETING CHIMERIC PHARMACEUTICAL - The present invention is based on the discovery of a composition that provides targeted anti-microbial effect. Specifically the composition contains a targeting moiety which recognizes a target microbial organism and an anti-microbial peptide moiety which has anti-microbial activity. In addition, the present invention provides methods of treating a microbial infection, e.g., on mucosal surfaces by using the compositions provided by the present invention. | 2010-07-22 |
20100184655 | MODIFIED ERYTHROPOIETIN - This invention relates to novel protein conjugates, in particular, to novel pegylated proteins, and their methods of making and use. One aspect of the present invention relates to pegylated-erythropoietin having greater clinical efficacy and stability during shipment and storage than current erythropoietin formulations. | 2010-07-22 |
20100184656 | PANTROPIC NEUROTROPHIC FACTORS - Pantropic neurotrophic factors which have multiple neurotrophic specificities are provided. The pantropic neurotrophic factors of the present invention are useful in the treatment of neuronal disorders. Nucleic acids and expression vectors encoding the pantropic neurotrophins are also provided. | 2010-07-22 |
20100184657 | METHODS OF TREATING EPITHELIAL LESIONS OUTSIDE THE STOMACH AND INTESTINES - Intestinal trefoil factors and nucleic acids encoding intestinal trefoil factors are disclosed. The intestinal trefoil factors disclosed are resistant to destruction in the digestive tract and can be used for the treatment of peptic ulcer diseases, inflammatory bowel diseases, and other insults. | 2010-07-22 |
20100184658 | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF TYPE 1 DIABETES - The present invention relates generally to the identification of biological markers associated with an increased risk of developing Diabetes, as well as methods of using such biological markers in diagnosis and prognosis of Diabetes. The biological markers of the invention may indicate new targets for therapy or constitute new therapeutics for the treatment or prevention of Diabetes. | 2010-07-22 |
20100184659 | Sustained-Release Formulations Comprising Crystals, Macromolecular Gels, and Particulate Suspensions of Biologic Agents - The present invention is directed to sustained release formulations of biologic agents which permit persistent bioavailability. Preferred biologic agents include bone morphogenetic proteins. Diseases susceptible to amelioration and/or treatment with the formulations of the present invention include skeletal tissue diseases such as, but not limited to, osteoarthritis and other osteochondral diseases. The sustained release formulations of the present invention are especially suitable for treatment of minimally-vascularized or non-vascularized tissue sites such as, but not limited to, intra joint, interarticular, or intraminiscal sites. | 2010-07-22 |
20100184660 | SINGLE EXON GENES ENCODING FOR NOVEL BIO-ACTIVE PEPTIDES - The present invention relates to novel bio-active peptide hormone, process for the production of the same, and use of the same. The present invention identified novel bioactive peptide precursor and salts thereof which can be used as drugs, for example therapeutic polypeptides, ligands to discover relevant targets (e.g. GPCRs) or targets for drug intervention. | 2010-07-22 |
20100184661 | CONJUGATE COMPRISING ANGIOSTATION OR ITS FRAGMENT, THE METHOD FOR PRODUCING THE CONJUGATE AND USE THEREOF - The present invention provides an anti-tumor or anti-angiogenesis medicament, the combination or kit containing the medicament, and the method for producing the same. The anti-tumor or anti-angiogenesis medicament contains a conjugate comprising a modifying agent and the angiostatin or its fragments, wherein the conjugate exhibits prolonged in vivo half-life as compared to an unmodified angiostatin or its fragments. The modifying agent is selected from the group consisting of macromolecular polymers, protein molecules or fragments thereof, peptides, small molecules, or chemical substances of any other forms. | 2010-07-22 |
20100184662 | METHOD FOR ASSAYING ANTIBODIES IN BODY FLUIDS BY IMMUNE REACTION WITH GLYCOPROTEIN 2 (GP2) FROM ZYMOGENIC GRANULES OF THE PANCREAS FOR THE DIFFERENTIAL DIAGNOSIS OF INFLAMMATORY INTESTINAL DISEASES AND CHRONIC PANCREATITIS - The invention relates to a method for the detection of antibodies from body fluids via immune reaction with GP2 from pancreatic zymogenic granules, immunoreactive sequences or analogs thereof, excluding tissue sections. | 2010-07-22 |