28th week of 2010 patent applcation highlights part 33 |
Patent application number | Title | Published |
20100178614 | METHOD FOR MANUFACTURING A LENS - In the present invention a mask ( | 2010-07-15 |
20100178615 | METHOD FOR REDUCING TIP-TO-TIP SPACING BETWEEN LINES - This invention provides a method for reducing tip-to-tip spacing between lines using a combination of photolithographic and copolymer self-assembling lithographic techniques. A mask layer is first formed over a substrate with a line structure. A trench opening of a width d is created in the mask layer. A layer of a self-assembling block copolymer is then applied over the mask layer. The block copolymer layer is annealed to form a single unit polymer block of a width or a diameter w which is smaller than d inside the trench opening. The single unit polymer block is selectively removed to form a single opening of a width or a diameter w inside the trench opening. An etch transfer process is performed using the single opening as a mask to form an opening in the line structure in the substrate. | 2010-07-15 |
20100178616 | METHOD OF MAKING A ROUGH SUBSTRATE - A method of making a rough substrate includes: (a) forming a first oxide layer; (b) coating a photoresist layer; (c) exposing and developing the photoresist layer; (d) etching parts of the first oxide layer such that parts of the first oxide layer are formed into a plurality of sacrificial protrusions; (e) removing the photoresist regions; (f) depositing on the substrate layer and the sacrificial protrusions a second oxide layer; (g) etching the second oxide layer so as to leave portions of the second oxide layer; and (h) etching additionally the sacrificial protrusions, the substrate layer, and the portions of the second oxide layer, thereby producing a plurality of flat recess bottom faces, and substrate protrusions. | 2010-07-15 |
20100178617 | PATTERNING PROCESS - A pattern is formed by coating a chemically amplified positive resist composition comprising a resin comprising acid labile group-containing recurring units and a photoacid generator onto a substrate, drying to form a resist film, exposing the resist film to high-energy radiation, PEB, developing to form a positive pattern, illuminating or heating the positive pattern to eliminate acid labile groups for increasing alkaline solubility and to induce crosslinking for imparting solvent resistance, coating a reversal film, forming a space pattern, and shrinking the space pattern. | 2010-07-15 |
20100178618 | PATTERNING PROCESS - A pattern is formed by coating a chemically amplified positive resist composition comprising a resin comprising acid labile group-containing recurring units and a photoacid generator onto a substrate, drying to form a resist film, exposing the resist film to high-energy radiation through a phase shift mask having a lattice-like array of shifters, PEB, developing to form a positive pattern, illuminating or heating the positive pattern to eliminate acid labile groups for increasing alkaline solubility and to induce crosslinking for imparting solvent resistance, coating a reversal film, and dissolving away the positive pattern in an alkaline wet etchant to form a pattern by way of positive/negative reversal. | 2010-07-15 |
20100178619 | METHOD FOR ENHANCING LITHOGRAPHIC IMAGING OF ISOLATED AND SEMI-ISOLATED FEATURES - The present invention relates to photolithography methods for enhancing lithographic imaging of isolated and semi-isolated features. A first layer of a first photoresist is formed over a substrate. A second layer of a second photoresist is formed over the first layer. The second photoresist includes a polymer containing an absorbing moiety. The second layer is exposed through a first patterned mask and developed to form a first relief image. The first relief image and the first layer are exposed through a second patterned mask. One of the first and the second patterned masks includes a dense pattern, while the other includes an isolated or a semi-isolated pattern. The first relief image and base soluble regions of the first layer are removed to form a second relief image with an isolated or a semi-isolated pattern. The second layer can also be bleachable upon exposure and bake in the present invention. | 2010-07-15 |
20100178620 | INVERTED PATTERN FORMING METHOD AND RESIN COMPOSITION - A method for forming an inverted pattern includes forming a photoresist pattern on a substrate, filling a space formed by the photoresist pattern with a resin composition including a polysiloxane and a solvent, and removing the photoresist pattern to form an inverted pattern. The resin composition includes (A) a polysiloxane obtained by hydrolysis and condensation of two types of hydrolysable silane compounds having a specific structure, and (B) an organic solvent containing an alcohol or ether having a specific structure. | 2010-07-15 |
20100178621 | DETERMINATION METHOD, EXPOSURE METHOD, DEVICE FABRICATION METHOD, AND STORAGE MEDIUM - The present invention provides a method of determining a structure of an antireflection coating formed on a substrate as an exposure target of an exposure apparatus, the method comprising steps of calculating, an intensity distribution of light diffracted by an original, based on information of an effective light source formed on a pupil plane of a projection optical system, and information of an original pattern, extracting diffracted light having an intensity of not less than a threshold from the intensity distribution calculated in the calculating step, and determining the structure of the antireflection coating, formed on the substrate, such that a reflectance of the antireflection coating falls within a target range when an incident angle of the diffracted light, which has the intensity of not less than the threshold and is extracted in the extracting step, on the antireflection coating formed on the substrate is an input. | 2010-07-15 |
20100178622 | OPERATING METHOD FOR A SOLID FUEL BURNER - The invention belongs to the engineering domain of heating systems, in particular heating systems for chipped to free-flowing fuels in solid form and relates to an operating method for a solid fuel burner. The aim of the invention is to design an operating method for a solid fuel burner, which achieves an efficient operating mode for said burner with the main focus on minimizing the production of aggressive substances such as acids. To achieve this, according to the invention, the burner operation has a double or triple combustion phase profile and the burner operates with two different groups of combustion material. | 2010-07-15 |
20100178623 | GAS SWITCH CAPABLE OF ADJUSTING FIRE INTENSITY FINELY - A gas switch capable of adjusting fire intensity finely includes a gas switch capable of adjusting fire intensity finely, comprising a switch body inside which a guide is installed, a fastener set that revolves inside the switch body and includes a hollow fastener and a fastener rod moving elastically through the faster, a drive component installed inside the switch body, which contains a rotating rod that can move along and rotate round the same shaft of the fastener set, a guide rod placed on the rotating rod and leaning on the guide, a regulating block installed movably at one end of the rotating rod and leaning against the fastener rod, and a connecting component for linking the drive component with the fastener set flexibly. | 2010-07-15 |
20100178624 | Method of Manufacturing Carbon-Rich Product and Co-Products - A method in which a parent hydrocarbon-rich material is processed so as to produce both a carbon-rich solid material that has a higher carbon to hydrogen ratio than that of the parent material and a carbon-deficient combustible gas that has a lower carbon to hydrogen ratio than the parent material. In the process, the material is activated by exposing it to a hot gas stream having elevated levels of one or both of carbon dioxide and water vapor. The combustible gas is combusted to produce heat. At least about 80% of the heat is used in one or more endothermic steps that include drying coal or biomass. | 2010-07-15 |
20100178625 | CANDLE BURNING DEVICE - The invention relates to a candle burning device, for example, a candle follower, which comprises a substantially planar body defining an outer rim, a plurality of vent openings, and an approximately centralized depressed recess, the recess defining an aperture for receiving a candle wick; a flange extending downward from the outer rim of the body; and wherein the device is formed of a heat conducting material. | 2010-07-15 |
20100178626 | BURNER HAVING VARIABLE OUTPUT STRUCTURE - An object of the present invention is to provide a burner having variable output structure that maintains the speed of a mixture injected through flame holes at a predetermined speed or more by supplying gas through a gas valve at a predetermined pressure or more, and prevents the occurrence of backfire at a low output by adjusting an opened area of the flame holes. In order to achieve the object, according to the present invention, a burner having variable output structure includes a flame-hole plate that includes a plurality of flame holes formed on the surface thereof exposed to a combustion chamber, and a flame hole adjusting unit that changes an output by adjusting the size of each flame hole according to load required in a combustion device. | 2010-07-15 |
20100178627 | AUTOMATIC FEED OVEN - An automatic feed oven for material processing ( | 2010-07-15 |
20100178628 | ORTHODONTIC DEVICE AND ORTHODONTIC METHOD - An orthodontic device and an orthodontic method that can prevent an orthodontic treatment from being eccentrically performed while aligning straightly tooth. The orthodontic device includes teeth-attachment unit attached to an orthodontic tooth object; and hook member provided in the teeth-attachment unit and having a connection part of traction unit for orthodontic treatment that is located in the vicinity of a center of resistance (CR) of a tooth. In addition, the orthodontic device includes teeth-attachment unit; and hook member provided in the teeth-attachment unit and having a connection part of traction unit for orthodontic treatment that is located in the vicinity of at least gingiva. Since the teeth-attachment unit of a bracket or a button is substantially horizontal to a traction line of the traction unit, it is possible to perform the orthodontic treatment effectively without eccentric phenomenon in which the tooth and a dental root are tilted. | 2010-07-15 |
20100178629 | SELF-LIGATING ORTHODONTIC BRACKET AND DEVICES FOR DEPLOYING SAME - An orthodontic bracket for coupling an archwire with a tooth includes a bracket body having an archwire slot for receiving the archwire and a movable member engaged with the bracket body and movable between opened and closed positions. The movable member includes a leading edge having a non-uniform pushing element configured to guide the archwire into the archwire slot as the movable member is closed. An associated method includes providing a movable member for an orthodontic bracket and providing a non-uniform pushing element on a leading edge thereof. The pushing element may include a chamfer formed along the leading edge of the movable member. | 2010-07-15 |
20100178630 | Dental Tray - The present invention is dental tray for applying treatment gels to a person's teeth. The dental tray is sized and shaped to accommodate the dental arch of a person's oral cavity and is constructed from a temperature-dependent material such that the dental arch forms to the shape of the person's teeth profile at temperatures at or above that of the person's oral cavity. Once the dental tray is fitted to the person's specific teeth profile, a treatment gel is applied to the dental tray, the dental tray reinserted and the treatment gel applied to the person's teeth by contact therewith. In one embodiment of the present invention, the treatment gel is applied to the unformed dental tray such that the dental tray is fitted to the person's teeth profile simultaneous with the treatment thereof. | 2010-07-15 |
20100178631 | Maxillary Bone Cutting and Injection System and Method of Using the Same - A bone cutting and injecting device for cutting maxillary bone and injecting a filler through the maxillary bone under a subantral membrane to separate the subantral membrane from the maxillary bone and fill the space formed therebetween. The device includes a hollow tubular element having a diameter sized to be inserted into a pilot hole in the maxillary bone, a piston longitudinally displaceable within the hollow tubular element, and a cutter mounted to the piston and operably disposed adjacent the distal end of the hollow tubular element. A fluid path is defined through the hollow tubular element for guiding the filler, and the cutter is configured to redirect the filler in a transverse or radial direction relative to the longitudinal axis of the tubular element. | 2010-07-15 |
20100178632 | Injection Distraction Device - A system for mitigating pain in a patient associated with needle penetration in the administration of medication, and in particular to a vibratory device configured to be utilized with a variety of existing hand-held intra-oral dental drills or like devices. The preferred embodiment of the present invention teaches a disposable or non-disposable vibratory tip formed to engage an off-the-shelf intra-oral dental drill, the vibratory tip utilizing an off-axis weight associated with a shaft drive engaging the dental drill, to provide a vibratory sensation to an application tip, the application tip configured to engage an area of a patient's mouth targeted for the subsequent needled administration of local anesthetic, or other medication. In use, the application tip is applied to the patient, the dental drill is engaged to rotate the shaft drive of the vibratory tip, vibrating same for period of time, so as to decrease the sensation of pain associated with the subsequent needle penetration. | 2010-07-15 |
20100178633 | APPARATUS AND METHOD FOR REMOVING ENAMEL FROM A PERSON'S TOOTH - According to one embodiment, an apparatus for removing enamel from a person's tooth includes a blade portion and a handle portion. The blade portion includes an abrasive surface adapted to remove enamel from the tooth in response to reciprocating movement of the abrasive surface against the enamel. The handle portion is coupled to the blade portion and includes first and second regions, the first region is proximal and the second region is distal to the blade portion. The first region includes a substantially solid cross-section with a substantially circular perimeter. The second region includes a substantially solid cross-section with at least a substantially semi-circular perimeter, the solid cross-section defining a notched region. The apparatus is adapted to be inserted via a pressure fit into a corresponding opening in a driver mechanism adapted to drive reciprocating movement of the blade portion and the abrasive surface. | 2010-07-15 |
20100178634 | DENTAL SANDING STRIP - An improved dental sanding strip for removing material between the teeth is provided. The dental sanding strip includes a lead portion extending from one end of the dental sanding strip to facilitate the insertion of the strip into the space between the teeth. The dental sanding strip is an elongated strip of film having a first end and a second end. The first end having an abrasive portion and the second end having a holding portion. A lead portion extends from the first end, the area having the abrasive portion. The lead portion is affixed to the first end in a suitable manner such as with adhesive or by heat welding. The first end of the dental sanding strip is tapered toward the lead portion providing a gradual transition from the lead portion to the full width dental sanding strip. The lead portion of the dental sanding strip is inserted between the teeth by first inserting a free end of the lead portion into the space between the teeth. The dentist then grasps the lead portion and pulls the lead portion thereby permitting the abrasive portion of the dental sanding strip to contact the area on the tooth to be removed. The dentist may then manipulate the dental sanding strip to remove any unwanted material between the teeth. The dentist uses a back-and-forth motion, or a circular motion, to remove the unwanted material between the teeth. | 2010-07-15 |
20100178635 | Dental Prosthesis Stabilizer - An improved dental prosthesis stabilizer includes two arms connected to each other by a hinge joint and with which an upper dental prosthesis and a lower dental prosthesis are coupled to one another. A spring is provided at the hinge joint with which the upper prosthesis and the lower prosthesis are pushed away from each other. At least one of the arms is telescopic and is formed of a bent distal end of the spring, which can be axially moved in a bent guide. The guide is fixed on the upper dental prosthesis or the lower dental prosthesis or is embedded therein. | 2010-07-15 |
20100178636 | CERAMIC BODY AND PROCESS FOR THE PREPARATION THEREOF - A process for the preparation of ceramic dental implants having a surface for improving osseointegration, wherein the following process steps are performed for preparing such surface: —preparation of a ceramic blank having a surface; —treating at least one partial area of the surface of the ceramic blank by an ablating process that produces a surface roughness of the surface that corresponds to a treatment by sand blasting under a blasting pressure of from 1.5 bar to 8 bar and with a grain size of the blasting media used for sand blasting of from 30 μm to 250 μm; —followed by a chemical treatment of said at least one partial area of the surface of the ceramic blank treated with the ablating process; —followed by a thermal treatment of the blank whose surface has been subjected to said ablating and chemical treatments at temperatures of >125° C. > A ceramic body obtainable by the process according to the invention is also described. | 2010-07-15 |
20100178637 | INTERACTIVE METHOD FOR HELPING THE DRIVER OF A MOTOR VEHICLE TO ADOPT AN ECONOMICAL DRIVING STYLE AND VEHICLE USING THIS METHOD - The invention relates to an interactive driving assistance method. This method involves selecting a desired driving style, and analysing (F | 2010-07-15 |
20100178638 | Method for teaching grammar through a series of steps - A method for teaching grammar where each lesson focuses on a different element of grammar id disclosed. These lessons are preferably arranged not by parts of speech, but rather are grouped such that subsequent lessons build on previously learned lessons. Identifying an element of grammar is achieved through a series of steps, whereby if these steps are followed exactly, the element of grammar can easily be identified. At least one of the steps includes a question, where the answer the question is the element of grammar to be identified by the user. | 2010-07-15 |
20100178639 | TRAINING ASSISTING APPARATUS, TRAINING ASSISTING METHOD, AND TRAINING ASSISTING PROGRAM - An examinee is subjected to an image or a sound suitable for the examinee's overcoming his worries in accordance with change in a physical state of the examinee. The training assisting apparatus according to the present invention is at training assisting apparatus for assisting an examinee in overcoming the examinee's worries by displaying a training image, including: a display section that displays the training image; a display ratio storage section that stores a change quantity of a display ratio of the training image displayed on the display section, in association with a physical state of the examinee; a physical state acquiring section that acquires the physical state of the examinee looking at the training image displayed on the display section; a display ratio extraction section that extracts the change quantity of the display ratio of the training image stored in the display ratio storage section in association with the physical state of the examinee acquired by the physical state acquiring section; and a display control section that changes the display ratio of the training image displayed on the display section, in accordance with the display ratio of the training image extracted by the display ratio extraction section. | 2010-07-15 |
20100178640 | COMPUTERIZED TEST APPARATUS AND METHODS FOR QUANTIFYING PSYCHOLOGICAL ASPECTS OF HUMAN RESPONSES TO STIMULI - A computerized method and apparatus for measuring effects of distraction on a human subject, including presenting at least one stimulus, at least one visual distraction and at least one audio distraction to a subject; measuring at least one aspect of at least one of the subject's commissions and omissions responsive to the stimulus; computing an indication of quality of at least one of the subject's commissions and omissions when visual distraction is present; and computing an indication of quality of at least one of the subject's commissions and omissions when audio distraction is present. | 2010-07-15 |
20100178641 | Apparel fastening learning apparatus - An apparel fastener learning apparatus for developing and disabled children, the mentally impaired, and the elderly is described that includes a first fastener plate having a plug and a second plate having a socket. The first plate has a predefined shape that is approximately identical to the shape of the second plate. The first plate includes a symbol that is in accordance with the shape of the fastener apparatus. In a first position, the first and second plates are snapped with the plug and the socket. In a second position, the first plate and the second plate are separated from each other. The first plate is snapped with only the second plate of the same fastener apparatus and not with a second plate of another fastener apparatus. In one embodiment, the fastener plates are securely coupled with apparels either by sewing along predefined holes or by using prongs. | 2010-07-15 |
20100178642 | SIMULATION DEVICE FOR TRACKING THE RESPECTIVE MOTIONS OF AT LEAST TWO INSTRUMENTS - The present invention relates to a simulation device ( | 2010-07-15 |
20100178643 | ANASTOMOSIS DEPLOYMENT FORCE TRAINING TOOL - An anastomosis training device and related methods of use that provides medical professionals with real-time feedback of pulling force. The anastomosis training device can include a housing portion, a spring member, a proximal catheter portion and a distal catheter portion. The housing portion can include an external tubing member that slidingly retains an internal tubing element and the spring member. A proximal wire assembly attaches the spring member to a manipulation assembly and a distal wire assembly attaches the spring member to a retention member that allows the anastomosis training tool to be anchored to a suitable surface. As a user applies a pulling force to the manipulation assembly, the internal tubing member is slidably withdrawn from the external tubing member to expose a visible force scale that indicates the level of pulling force being applied by the user. | 2010-07-15 |
20100178644 | INTERACTIVE SIMULATION OF BIOLOGICAL TISSUE - A simulator simulates interaction between a surgical tool and biological tissue, providing real time visual and/or haptic feedback. The simulator receives tool input device information representative of a user's movement of a physical tool. The simulator simulates, based on the tool input device information, an interaction between the simulated tool and simulated biological tissue. The simulator uses multiple computational threads, some of which provide their calculations to interrelated threads for use. The simulator displays a visual representation of the simulated interaction between the simulated tool and the simulated biological tissue and provides haptic feedback to the user. The threads may operate asynchronously and have different spatial and/or temporal resolutions. Threads may be selectively activated and deactivated. Threads may move their spatial coverage. | 2010-07-15 |
20100178645 | PARTICIPANT RESPONSE SYSTEM WITH QUESTION AUTHORING/EDITING FACILITY - A participant response system ( | 2010-07-15 |
20100178646 | DEMONSTRATIVE METHODS FOR TOILET TISSUE PRODUCTS - Demonstrative methods for sanitary tissue products, for example toilet tissue products, and more particularly, methods for demonstrating absorbency-based consumption differences between two or more toilet tissue products, and toilet tissue product packages and marketing articles that evidence absorbency-based consumption differences between toilet tissue products are provided. | 2010-07-15 |
20100178647 | SIMULATION OF NORMAL FRESH BLOOD PLATELETS - The present invention provides for novel analogs of fresh human platelets for use in hematological instrument. Methods for preparing such analogs are also described. | 2010-07-15 |
20100178648 | IN VITRO METHODS FOR EVALUATING THE IN VIVO EFFECTIVENESS OF DOSAGE FORMS OF MICROPARTICULATE OR NANOPARTICULATE ACTIVE AGENT COMPOSITIONS - Disclosed are in vitro methods for evaluating the in vivo redispersibility of dosage forms of poorly water-soluble active agents. The methods utilize media representative of in vivo human physiological conditions. | 2010-07-15 |
20100178649 | GENOMICS-BASED QUALITY DIAGNOSTICS FOR PREDICTION OF COLD-SWEETENNG DURING STORAGE IN PROCESSING POTATO - The invention relates to the field of quality testing of fresh potato products. Methods, carriers and kits for determining and/or predicting the quality stage of potato batches are provided. | 2010-07-15 |
20100178650 | CAPILLARY-BASED CELL AND TISSUE ACQUISITION SYSTEM (CTAS) - The present invention relates to a capillary-based cell and tissue acquisition system that integrates the capillary approach with a microscope manipulator to collect and sort cells of interest. Cells of interest are determined by using a laser beam focus to identify the initial contact between the capillary and the cells. | 2010-07-15 |
20100178651 | Bifunctional Predictors of Cancer Treatment Sensitivity and Resistance - The present invention provides the identification of genes that are expressed in tumors to indicate responsiveness or resistance to an agent or class of agents. More particularly, these genes show expression associated with responsiveness to one agent or class of agents is inversely related to expression in association with another class of agents. One or more of theses genes of the present invention can be used as markers (or surrogate markers) to identify tumors that are likely to be successfully treated by the responsive agent as well as to identify tumors that should avoid treatment by the resistant agent. | 2010-07-15 |
20100178652 | Materials and Methods for the Detection, Prevention and Treatment of Autoimmune Disease - The subject invention provides materials and methods for the detection, prevention, and treatment of diabetes and other autoimmune conditions. | 2010-07-15 |
20100178653 | GENE EXPRESSION SIGNATURE FOR CLASSIFICATION OF CANCERS - The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules relating thereto. Classification according to a microRNA tree-based expression framework allows optimization of treatment, and determination of specific therapy. | 2010-07-15 |
20100178654 | REAGENT AND REAGENT KIT FOR ANALYSIS OF IMMATURE LEUKOCYTE - The present invention provides a reagent for analysis of immature leukocytes comprising:
| 2010-07-15 |
20100178655 | SINGLE-CELL NUCLEIC ACID ANALYSIS - The present invention provides methods for analysis of genomic DNA and/or RNA from small samples or even single cells. Methods for analyzing genomic DNA can entail whole genome amplification (WGA), followed by preamplification and amplification of selected target nucleic acids. Methods for analyzing RNA can entail reverse transcription of the desired RNA, followed by preamplification and amplification of selected target nucleic acids. | 2010-07-15 |
20100178656 | Multiple Analysis of Blood Samples - The invention relates to a method for detecting a plurality of antigenic molecules carried by erythrocytes and/or a plurality of anti-erythrocyte antibodies of an individual, comprising bringing a sample into contact with distinguishable beads, on which are attached a) antibodies specific for said antigens, or b) erythrocytes, erythrocyte membrane fragments or blood group antigens. | 2010-07-15 |
20100178657 | MOLECULAR ASSEMBLY ON A SUBSTRATE - The present invention relates to a molecular assembly on a substrate usable for studying and/or performing biological interactions and/or reactions The invention further relates to an in vitro method to provide a substrate with a heparin coating presenting biotinylated biomolecules comprising linking avidin to a surface capable of binding avidin. A heparin conjugate is then linked to the avidin treated surface to form a layer of heparin thereon. Finally, a biotinylated biological probe or biomolecule is linked to the avidin through the layer of heparin thereby forming an essentially biologically inert surface with biotinylated probes extending out from the surface. | 2010-07-15 |
20100178658 | SCREENING ASSAYS FOR INHIBITORS OF BETA AMYLOID PEPTIDE ION CHANNEL FORMATION - Screening assays and methods of employing the screening assays designed to identify potential inhibitors of amyloidal neurodegenerative disease. The screening assays comprises providing a membrane construct disposed on a substrate and contacting the membrane construct with Aβ peptide capable of forming an Aβ peptide ion channel in the construct. The membrane construct is then contacted with a test compound. Aβ peptide ion channel activity is determined after the construct has incubated with the Aβ peptide in the presence and in the absence of the test compound. A reduction in the Aβ peptide ion channel activity of the membrane construct contacted with the test compound in comparison to a different membrane construct contacted with the same Aβ peptide in the absence of said test compound indicates that the test compound is an inhibitor of amyloidal neurodegenerative disease. | 2010-07-15 |
20100178659 | METHOD OF MEASURING HbA1c - A method of measuring HbA1c is provided that, even with a whole blood sample after storage, measurement accuracy substantially equal to a whole blood sample right after collection can be maintained. Whole blood is stored in a presence of a glycolytic inhibitor and protease is added to the stored whole blood sample to cleave hemoglobin in the whole blood sample. Then a glycated part of a hemoglobin fragment thereby obtained is treated with fructosyl amine oxidase. Thereafter, a glycation degree of HbA1c is determined by measuring a redox reaction between the glycated part and the fructosyl amine oxidase. Further, instead of storage of the whole blood in a presence of the glycolytic inhibitor, a strong electrolyte substance such as KCl, K | 2010-07-15 |
20100178660 | METHODS AND KITS FOR DETECTING HEMOGLOBIN IN TEST SAMPLES - The present invention relates to methods of detecting hemoglobin in a test sample. These methods can be used to diagnose a subject suffering from a genetic disorder relating to hemoglobin metabolism, to determine the eligibility of a subject to be a blood donor, to determine the age of a stored blood sample or to identify a hemolyzed plasma sample. The present invention also relates to kits for use in the above described methods. | 2010-07-15 |
20100178661 | AUTOMATIC TISSUE MICROARRAY APPARATUS AND METHOD FOR ARRAYING TISSUE USING THE SAME - Disclosed is an automatic tissue microarray apparatus that includes: a sample module being drivable and providing a space for mounting at least one donor block and at least one recipient block; an extract module being drivable in at least two directions and having at least one punching tip for punching a tissue from the at least one donor block and arraying the punched tissue in the at least one recipient block; and a controller for controlling the driving operations of the sample module and the extract module and, in response to an externally applied command, the punching and arraying operations of the extract module. The present invention securely provides convenience in use with improved work efficiency and contributes to precision of punching and arraying operations. | 2010-07-15 |
20100178662 | NON-INVASIVE HUMAN-HEALTH-MEASUREMENT SYSTEM AND METHOD - Methods and hand-held devices non-invasively measure a health parameter in an individual or a plurality of individuals. Plural hand-held devices may be provided to plural individuals. Each device may compute a score based on the assayed health parameter in the individual. A server on a computer network may receive the scores and determine a pattern based on the scores. The hand-held devices may be further configured to receive additional data from the individuals regarding activities that may affect the individuals' scores. The server may receive the additional data from the devices and determine additional patterns. | 2010-07-15 |
20100178663 | Apparatus And Methods For The Detection Of Plasma Metanephrines - Embodiments of the present invention feature the determination of normetanephrine, metanephrine and 3-methoxytyraminein raw human plasma with minimal sample pretreatment using a weak cationic extraction media to provide a selective sample clean-up and HILIC chemistries as indicators of pheochromoacytoma. | 2010-07-15 |
20100178664 | OPTICAL MEASUREMENT METHOD FOR DETERMINING THE PH OF A MEDIUM USING AGELADINE A AS A FLUORESCENT PH INDICATOR - An optical measurement method for determining a pH of a medium includes adding a fluorescent pH indicator to the medium. The pH indicator is based on naturally-obtained or synthesized ageladine A. The pH indicator is irradiated with light of at least one wavelength so as to provide fluorescence excitation of the pH indicator. An emitted fluorescence intensity of the pH indicator is detected as a measure for the pH of the medium. | 2010-07-15 |
20100178665 | Monitoring and Manipulating Cellular Transmembrane Potentials using Nanostructures - The use of nanostructures to monitor or modulate changes in cellular membrane potentials is disclosed. Nanoparticles having phospholipid coatings were found to display improved responses relative to nanoparticles having other coatings that do not promote localization or attraction to membranes. | 2010-07-15 |
20100178666 | SYSTEMS AND METHODS FOR FOCUSING PARTICLES - Provided is a method of focusing particles. The method includes: providing a suspension of the particles in a suspending medium; and flowing the suspension along a channel, such that the flowing suspension occupies a certain volume that has at least one cross-sectional dimension smaller than 100 μm. The suspending medium has such viscoelastic properties, that flowing the suspension in the channel directs at least some of the particles towards a focus region, enclosed in said certain volume. | 2010-07-15 |
20100178667 | PERIODIC ACID-SCHIFF STAINING WITH DETECTION IN THE INFRARED RANGE - Provided is a method of detecting the presence and quantitating the amount of glycogen from a biological sample. This method employs PAS staining with detection in the infrared range. | 2010-07-15 |
20100178668 | BIOLOGICAL REACTION APPARATUS WITH DRAINING MECHANISM - A biological reaction apparatus for receiving at least one substrate having a sample located in a sample region, and a separate cover, such that a reaction chamber is formed between the cover and substrate over the sample region, wherein the apparatus includes a locating means to locate the substrate; a cover locating means for locating and moving the cover with respect to the substrate; a fluid dispensing means for dispensing fluid into the reaction chamber; and a draining mechanism; wherein the draining mechanism includes wicking means. | 2010-07-15 |
20100178669 | Method for the Intensive Extraction of Cellular Compounds from Micro-Organisms by Continuous Culture and Extraction, and Corresponding Device - HA method is provided for extracting cellular compounds from micro-organisms. The method includes culturing the micro-organisms and extracting the cellular compounds from the micro-organisms. Each step is carried out in a continuous manner, wherein the extraction step is carried out separately from the culture step and in conditions of biocompatibility with the micro-organisms. The method further includes at least one step of recovering the cellular compounds and at least one step of recirculating the micro-organisms towards the culture step. | 2010-07-15 |
20100178670 | PROCESSES OF PRODUCING FERMENTATION PRODUCTS - The invention relates to a process of fermenting material derived from lignocellulose-containing material into a fermentation product by fermenting said material derived from lignocellulose-containing material using a fermenting organism obtained from a process of fermenting starch-containing material. | 2010-07-15 |
20100178671 | VECTOR CONSTRUCTS AND METHODS FOR EXPRESSING AND SECRETING POLYPEPTIDES IN FILAMENTOUS FUNGI USING A SELF-PROCESSING 2A CLEAVAGE SITE - The invention relates to a vector construct for expressing and secreting polypeptides in filamentous fungi, comprising, in 5′3′ direction, in functional linkage,
| 2010-07-15 |
20100178672 | CHO CELL - The current invention comprises a CHO cell which is expressing a constitutively active mitogenic receptor, a method of obtaining such a CHO cell, and a method for the expression of a heterologous polypeptide using a CHO cell according to the invention. | 2010-07-15 |
20100178673 | Methods of Gene Amplification and Expression - Disclosed are methods relating to amplification and expression of a nucleic acid sequence encoding a polypeptide of interest in recombinant cells, and cell lines and polypeptides produced from such methods. The methods disclosed herein permit the amplification of cell lines that express a polypeptide of interest in a relatively short period of time through the use of a bioreactor. | 2010-07-15 |
20100178674 | RECOVERY AND PURIFICATION OF B-PHYCOERYTHRIN PRODUCED BY PORPHYRIDIUM CRUENTUM USING TWO-AQUEOUS-PHASE SYSTEMS AND ISOELECTRIC PRECIPITATION - This invention focuses on a novel process in which | 2010-07-15 |
20100178675 | SYSTEM FOR EXTRACTING PROTEIN FROM A FERMENTATION PRODUCT - A method of producing bioproducts from a feedstock in a system configured to produce ethanol and distillers grains from a fermentation product is disclosed. A system configured to process feedstock into a fermentation product and bioproducts including ethanol and meal is disclosed. A bioproduct produced from a fermentation product produced from a feedstock in a biorefining system is disclosed. | 2010-07-15 |
20100178676 | METHODS FOR ANTIBODY PRODUCTION - The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system. | 2010-07-15 |
20100178677 | SYSTEM AND PROCESS FOR BIOMASS TREATMENT - A system including an apparatus is presented for treatment of biomass that allows successful biomass treatment at a high solids dry weight of biomass in the biomass mixture. The design of the system provides extensive distribution of a reactant by spreading the reactant over the biomass as the reactant is introduced through an injection lance, while the biomass is rotated using baffles. The apparatus system to provide extensive assimilation of the reactant into biomass using baffles to lift and drop the biomass, as well as attrition media which fall onto the biomass, to enhance the treatment process. | 2010-07-15 |
20100178678 | Method for producing cyclopent-4-ene-1,3-diol or cyclopent-4-ene-1,3-diol derivatives - The invention relates to a method for producing cis-cyclopent-4-ene-1,3-diol and cis-cyclopent-4-ene-1,3-dialkanoates by selective cis-1,2-reduction of 4-hydroxycyclopent-2-enone by means of a hydroboron, in the presence of substoichiometric quantities of a trivalent rare earth metal compound, to form cyclopent-4-ene-1,3-diol which can then be optionally reacted with an acylation agent to form cis-cyclopent-4-ene-1,3-dialkanoates, in order to simplify the reprocessing and without intermediate isolation. | 2010-07-15 |
20100178679 | PRODUCTION OF ISOPRENOIDS - The present invention provides methods for a robust production of isoprenoids utilizing the DXP biosynthetic path-way. The invention also provides nucleic acids, enzymes, expression vectors, and genetically modified host cells for carrying out the subject methods. | 2010-07-15 |
20100178680 | ROTATABLE PERFUSED TIME VARYING ELECTROMAGNETIC FORCE BIOREACTOR AND METHOD OF USING THE SAME - A rotatable perfused time varying electromagnetic force bioreactor with a rotatable perfusable culture chamber and a time varying electromagnetic force source operatively connected to the rotatable perfusable culture chamber. In use, the rotatable perfused time varying electromagnetic force bioreactor supplies a time varying electromagnetic force to the rotatable perfusable culture chamber of the rotatable perfused time varying electromagnetic force bioreactor to expand cells contained therein. | 2010-07-15 |
20100178681 | LIPID-FREE SCAFFOLDS FOR HUMAN VOLUME REPLACEMENT OR CELL CULTURE AND USE THEREOF - The present invention relates to lipid removed scaffolds(lipid-free scaffolds) for human tissue volume replacement or cell culture. More particularly, the present invention relates to a method for preparing lipid removed scaffolds(lipid-free scaffolds) for human tissue volume replacement or cell culture, the method comprising the steps of: fragmenting fat tissue to isolate lipids by ultrasonic treatment or high pressure nozzle spray; removing the isolated lipids and fat tissue from which lipids were not isolated to sterilize. According to the present invention, lipids are removed from fat tissue only by physical treatment to maintain the volume thereof and microstructures such as cellular membrane as much as possible and thus the inventive scaffolds are useful for human tissue volume replacement. | 2010-07-15 |
20100178682 | FLOW CYTOMETER HAVING CELL-SORTING FUNCTION AND METHOD OF SEPARATING LIVING CELLS - A liquid sample flow containing living cells is irradiated with measurement laser light and the photo data of at least either scattering light or fluorescence that is generated by each of the living cells in the liquid sample flow due to the irradiation with the measurement laser light is acquired. Based on the photo data thus acquired, it is determined whether each of the cells assignable to the respective photo data is an unnecessary living cell or a target living cell. Based on the determination results, a pulse voltage is then applied exclusively to the living cells having been determined as unnecessary living cells so that the unnecessary living cells are damaged and killed. | 2010-07-15 |
20100178683 | HAIR FOLLICLE GRAFT FROM TISSUE ENGINEERED SKIN - The present invention provides a hair graft comprising (a) tissue engineered skin comprising a tissue engineered epidermal layer, a tissue engineered dermal layer, and hair follicle progenitor cells and (b) a scaffold. The invention also provides methods of making and using the hair grafts of the present invention. | 2010-07-15 |
20100178684 | TRANSGENIC ONCOLYTIC VIRUSES AND USES THEREOF - The present disclosure relates to a recombinant oncolytic virus useful for inhibiting the growth of or killing tumor cells. More specifically, the recombinant oncolytic virus contains a heterologous nucleic acid sequence encoding an inflammation suppressive gene including, but not limited to, natural killer cell inhibitor, a chemokine binding protein, and an NF-κB inhibitor. Alternatively, the recombinant oncolytic virus contains a two or more heterologous nucleic acid sequences encoding one or more inflammation suppressive genes including, but not limited to, natural killer cell inhibitor(s), one or more chemokine binding protein(s), and/or one or more NF-κB inhibitor(s). Optionally, a recombinant oncolytic virus may further comprise one or more heterologous viral internal ribosome entry site (IRES) that is neuronally-silent. Such recombinant oncolytic viruses can be used to treat singular tumors or multi-focal tumors, such as those found in hepatocellular carcinoma or other cancers. | 2010-07-15 |
20100178685 | METHOD AND DEVICE FOR AERATION, PARTICULARLY FOR MICROBIOLOGICAL FERMENTATION AND FOR CELL CULTIVATION - The invention relates to a method and a device for aeration, particularly for microbiological fermentation and for cell cultivation in a closed chamber. The invention comprises a sterilizable reactor ( | 2010-07-15 |
20100178686 | Method and Apparatus for Providing a Photobioreactor - The present invention provides for a photobioreactor for the cultivation of photosynthetic microorganisms and comprises a hydraulic circuit through which an aqueous solution containing culture of at least one type of photosynthetic organism circulates and gets exposed to a light source. The photobioreactor also comprises a means for feeding carbon dioxide into the system, a means for oxygen degasification, and a means for injecting nutrients into the system. The hydraulic circuit is comprised of two open receiving channels at the same relative elevation, a set of transparent or translucent tubes which connect receiving channels to each other, and at least one fluid moving device to move the fluid from the first to the second receiving channels through the tubes. Each receiving channel also comprises a dam which assists in maintaining two different surface levels of the aqueous solution within the upstream and downstream portions of each receiving channel. | 2010-07-15 |
20100178687 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 2010-07-15 |
20100178688 | ACOUSTIC WAVE BIOSENSOR FOR THE DETECTION AND IDENTIFICATION OF CHARACTERISTIC SIGNALING MOLECULES IN A BIOLOGICAL MEDIUM - An acoustic wave biosensor comprises a plurality of spaced apart electrodes disposed on a substrate of piezoelectric material and having a biolayer matched to a specific type of autoinducer signaling molecule to be detected. The biolayer comprises a layer of heterobifunctional molecules disposed on the electrodes and on the piezoelectric material between the electrodes, and a plurality of bioreceptor molecules which bind exclusively with the specific type of autoinducer signaling molecule to be detected. The bioreceptor molecules are supported by the layer of heterobifunctional molecules, and a hydrogel layer surrounds the bioreceptor molecules to support a three-dimensional structure thereof. The bioreceptor molecules can bind with the specific type of autoinducer signaling molecule to be detected, and the biolayer is reactive thereto such that corresponding autoinducer signaling molecules bind to the biolayer and detectably vary acoustic characteristics of the acoustic wave biosensor. | 2010-07-15 |
20100178689 | DEVICE FOR DECANTATION DEPOSITION OF CELLS ON AN ANALYSIS PLATE - A device includes a reception chamber ( | 2010-07-15 |
20100178690 | BIOMOLECULE DETECTION APPARATUS AND BIOMOLECULE MEASUREMENT SYSTEM - The present invention relates to a biomolecule detection apparatus and a biomolecule measurement system. A biomolecule detection apparatus according to an aspect of the invention may include: an upper disc having a fluid inlet in a thickness direction through which a fluid is introduced to the inside; a lower disc laminated to the upper disc and having a fluid outlet in a thickness direction through which the fluid exits to the outside; detection units provided on each of the upper disc and the lower disc and including spherical microbeads having surfaces coated with materials used to capture biomolecules; and via holes provided along the edge of each of the upper disc and the lower disc so that the fluid flows between the upper disc and the lower disc. | 2010-07-15 |
20100178691 | Systems, Methods, and Apparatus for Single Molecule Sequencing - An embodiment generally relates to a system for analysis of an analyte. The system can include a transparent substrate. The system also includes an excitation light source configured to induce an evanescent wave excitation of a fluorescently labeled molecule near the access to the transparent substrate and a detector for detecting the fluorescently labeled molecule. | 2010-07-15 |
20100178692 | MODEL CELL CHIP, APPARATUS FOR EVALUATING DRUG EFFECT USING THE MODEL CELL CHIP AND METHOD OF EVALUATING DRUG EFFECT - The present invention provides an apparatus for evaluating a drug effect enabling on-chip evaluation of the effect of a drug while the drug is acting on hERG-expressing cells. The present invention also provides a myocardial toxicity test apparatus and method therefor enabling in vitro myocardial toxicity testing that has previously been performed in vivo. | 2010-07-15 |
20100178693 | GAS DECOMPOSING APPARATUS - A gas cracking apparatus adapted to simultaneously efficiently discharge gas heavier than air and gas lighter than air resulting from assimilations of malodorous gas and greenhouse gas. The main frame of the gas cracking apparatus includes a closed metallic circular tube or angular tube. This tube is provided at its superior portion with a superior vent and provided at its inferior portion with an inferior vent, and the tube is further provided with a gas inlet disposed between the superior vent and the inferior vent. | 2010-07-15 |
20100178694 | CELL CULTURE MODULE - A cell culture module includes a sealing member | 2010-07-15 |
20100178695 | SPECIMEN PREPARATION APPARATUS, SPECIMEN PREPARATION/ANALYSIS SYSTEM AND SPECIMEN PLATE - Provided is a specimen preparation apparatus capable of supplying a specimen from the specimen preparation apparatus to a specimen analyzer without burdening an operator. This specimen preparation apparatus comprises a stained specimen preparation part for preparing a specimen on a slide glass and staining the specimen, a keeping part for storing the stained specimen slide glass prepared in the stained specimen preparation part and a control part for deciding whether to supply the stained specimen slide glass to the keeping part or to the external apparatus. | 2010-07-15 |
20100178696 | IN VIVO GENOME-WIDE MUTAGENESIS - Disclosed herein are compositions and methods for deleting or duplicating DNA in a mammalian genome. Also disclosed are compositions and methods for generating a random genome-wide chromosome rearrangement. Also disclosed are compositions and methods for streamlined construction of gene targeting vectors. | 2010-07-15 |
20100178697 | SYSTEM, APPARATUS AND METHOD FOR MATERIAL PREPARATION AND/OR HANDLING - Oscillating angularly rotating a container containing a material may cause the material to be separate. Denser or heavier material may unexpectedly tend to collected relatively close to the axis of rotation, while less dense or light material may tend to collect relatively away from the axis of rotation. Oscillation along an arcuate path provides high lysing efficiency. Alternatively, a micromotor may drive an impeller removably received in a container. Lysing may be implemented in batch mode, flow-through stop or semi-batch mode, or flow-through continuous mode. Lysing particulate material may exceed material to be lysed or lysed material and/or air may be essentially eliminated from a chamber to increase lysing efficiency. | 2010-07-15 |
20100178698 | TISSUE CULTURE DEVICE - A tissue culture device includes a container having one or more upstanding walls extending upwardly from a floor. The floor of the container has a media having nutrients or growth substances therein. A plurality of plant tissues are within the container compartment and are placed upon a screen between the plant tissues and the media. The screen is tamped downwardly onto the media so that the plant tissues can get nutrients from the media, and so that waste products are transferred into the media. The screen is also removable through the open end of the container so as to remove all of the plurality of the plant tissues from the container at once. The plant tissue device can then be placed in another container having any cultured media as needed for the correct maintenance, propagation and development of plant tissue in culture. | 2010-07-15 |
20100178699 | MULTI-CHAIN LIPOPHILIC POLYAMINES - There are provided multi-chain lipophilic polyamine compounds and derivatives thereof, pharmaceutical formulations comprising the same, method of making and using said compounds or formulations. | 2010-07-15 |
20100178700 | NOVEL THYMIC CELLULAR POPULATIONS AND USES THEREOF - The present invention relates generally to novel thymic cellular populations and, more particularly, to novel thymic epithelial cellular populations. Most particular, the present invention is directed to novel thymic epithelial progenitor cell populations. The cellular populations of the present invention are useful in a wide range of clinical and research settings including, inter alia, the in vitro or in vivo generation of thymic epithelial cell populations and the therapeutic or prophylactic treatment of a range of conditions via the administration of these cells. Also facilitated is the design of in vitro based screening systems for testing the therapeutic impact and/or toxicity of potential treatment or culture regimes to which thymic epithelial cells may be exposed. In another aspect, the present invention is directed to a method of identifying thymic epithelial cellular subpopulations and, more particularly, thymic epithelial progenitors by screening for the co-expression of markers including MHC Class II, UEA1 and Ly51. This method is useful in a range of applications including, but not limited to, assessing or monitoring for the presence of thymic epithelial cell populations and/or facilitating the isolation of or enrichment for these cellular populations of use in a range of research and clinical applications. | 2010-07-15 |
20100178701 | PROLIFERATION CULTURE METHODS USING MICRO-SCAFFOLDS FOR REGULATIONS OF CELL-TO-CELL SIGNALS - The present invention aims to provide a three-dimensional cell culture method for increasing cell proliferation efficiency by suitably regulating the proliferation-inducing and proliferation-inhibitory signals between cells, which are the greatest variables in proliferation efficiency. For this purpose, the present invention provides a method for culturing cells using micro-scaffolds by the regulation of cell-to-cell signals, the method comprising repeatedly performing any one or both of the following processes a) and b) so as to regulate proliferation-inducing and proliferation-inhibitory signals between the cells: a) a process of gradually adding the micro-scaffolds, in which a small amount of the micro-scaffolds are used in an initial stage in order to maintain a suitable distance between the cells (cell concentration relative to the micro-scaffolds), and the amount of the micro-scaffolds is then increased slowly according to cell proliferation rate! and b) a periodic shaking process, in which shaking is performed in order to separate connected cells from each other by a physical force, after the cells are incubated for more than a given period of time. | 2010-07-15 |
20100178702 | EXTRACELLULAR VESICLES FROM NON-PATHOGENIC AMOEBAE USEFUL AS VEHICLE FOR TRANSFERRING A MOLECULE OF INTEREST TO AN EUKARYOTIC CELL - The invention relates to membrane vesicles from non-pathogenic amoeba, in particular from the amoeba | 2010-07-15 |
20100178703 | SINGLE-SENSOR METER SYSTEM WITH NO SENSOR HANDLING AND METHOD OF USING THE SAME - A single-sensor meter system for dispensing sensors for testing of an analyte concentration in a fluid comprises a container assembly and a single-sensor meter. The container assembly includes inner and outer cartridges. The inner cartridge includes a plurality of test sensors and a mechanical mechanism. The container assembly forms exactly one opening for dispensing the test sensors one at a time. The opening is covered by an end cap so as to assist in preventing or inhibiting moisture from entering the interior of the container assembly. The mechanical mechanism is adapted to advance the plurality of test sensors. The single-sensor meter is adapted to align with and operatively connects to the container assembly. The single-sensor meter includes a test-sensor extraction mechanism adapted to grip a test sensor and pull the test sensor through the opening to a dispensed position. | 2010-07-15 |
20100178704 | RAPID SENSING OF TOXIC METALS WITH HYBRID INORGANIC MATERIALS - Methods for rapid sensing of dissolved toxic heavy metals use a hybrid inorganic material (“HIM”), which is synthesized from hydrated iron oxide (“HFO”) and calcium magnesium silicate. HIM thus synthesized is used in sensing dissolved toxic heavy metals. Water containing toxic heavy metals (e.g., lead, copper, zinc, nickel, etc.) is passed through a sorbent bed of HIM, whereupon it shows a sharp drop in pH after a certain length of time. The presence of HFO and calcium magnesium silicates in HIM synergistically provide a precipitous drop in pH, which is characteristic of the concentration and type of toxic heavy metal. Therefore, observing a change in pH indicates the presence and identity of heavy metal ions in a test water sample. | 2010-07-15 |
20100178705 | Apparatus, System And Method For Consumer Detection Of Contaminants In Food Stuffs - An apparatus, system and method of detecting contaminants, such as melamine, in at least one ingestible item. The apparatus, system and method may include a disposable notched probe having therein at least one send and one receive fiber optic, or electrical, or heat source, and a reactant associated with said disposable notched probe, wherein a reaction of the reactant with at least a portion of the ingestible item indicates, to the consumer user, a presence of a contaminant. | 2010-07-15 |
20100178706 | METHOD FOR MONITORING CONCENTRATION OF WATER BORNE SUBSTANCE IN AN AQUEOUS MEDIUM - A method for monitoring the concentration of water borne substances in an aqueous medium, by introducing a defined amount of the aqueous medium into a gas circulatory system of an analytical apparatus which extends through a high temperature reaction chamber and a measuring chamber. The introducing of the aqueous medium occurs upstream of the high temperature reaction chamber or into it. The aqueous medium is evaporated in the high temperature reaction chamber, the water borne substance with at least one reaction partner in the high temperature reaction chamber reacts to a gaseous reaction product, and a current value of a measured variable is registered, which is a function of the concentration of the chemical species of the reaction product in the gas circulatory system. The concentration of the chemical species of the reaction product in the gas circulatory system depends, on the one hand, on a time-dependent state of the gas circulatory system and, on the other hand, on the concentration of the substance in the aqueous medium; ascertaining the concentration of the substance in the aqueous medium by applying the current value of the measured variable,wherein, in the ascertaining of the concentration of the substance in the aqueous medium, the contribution to the concentration of the chemical species of the reaction product in the gas circulatory system by the state of the gas circulatory system is ascertained on the basis of a model of the state, and a correction of the concentration of the chemical species of the reaction product in the gas circulatory system occurs on the basis of this contribution. | 2010-07-15 |
20100178707 | VITAMIN D DEFICIENCIES - Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided. | 2010-07-15 |
20100178708 | LIQUID FLUID TESTING INSTRUMENT AND TESTING METHOD - Printed surface | 2010-07-15 |
20100178709 | Magnetic Microspheres For Use In Fluorescence-Based Applications - Microspheres, populations of microspheres, and methods for forming microspheres are provided. One microsphere configured to exhibit fluorescent and magnetic properties includes a core microsphere and a magnetic material coupled to a surface of the core microsphere. About 50% or less of the surface of the core microsphere is covered by the magnetic material. The microsphere also includes a polymer layer surrounding the magnetic material and the core microsphere. One population of microspheres configured to exhibit fluorescent and magnetic properties includes two or more subsets of microspheres. The two or more subsets of microspheres are configured to exhibit different fluorescent and/or magnetic properties. Individual microspheres in the two or more subsets are configured as described above. | 2010-07-15 |
20100178710 | Mass Labels - A mass label for labelling and detecting a biological molecule by mass spectroscopy, which label comprises the following structure: X-L-M wherein X is a mass marker moiety comprising the following group: formula (I), wherein the cyclic unit is aromatic or aliphatic and comprises from 0-3 double bonds independently between any two adjacent atoms; each Z is independently N, N(R | 2010-07-15 |
20100178711 | VIAL SYSTEM AND METHOD FOR PROCESSING LIQUID-BASED SPECIMENS - A vial-based system and method for handling and processing specimens of particulate matter-containing liquid directly in the vial. A processing assembly, which includes a stirrer and a particulate matter separation chamber, is releasably coupled to the inside of the vial cover. The processing assembly remains with the cover when the vial is opened to insert a specimen therein. Application of a particular external force to the closed vial detaches the processing assembly from the cover so that it remains in the vial, for access by automated or manual laboratory equipment, when the cover is subsequently removed. | 2010-07-15 |
20100178712 | Microplates containing microsphere fluorescence standards, microsphere standards, and methods for their use - Microplates containing spherical “microsphere” fluorescence standards are disclosed. The microplates can be prepared using several methods including airbrushing, application with an inkjet printer, or controlled evaporation. Spherical bead standards containing two or more regions stained with dyes of different fluorescence lifetimes, and methods for their preparation are also disclosed. The microplates can be used as calibration standards for fluorescence and confocal microscopes, and as calibration tools for microscope-based high content screening (“HCS”) instruments. | 2010-07-15 |
20100178713 | TARGET SUBSTANCE-DETECTING ELEMENT - A substrate of a target substance-detecting element for detecting a target substance in a specimen based on localized surface plasmon resonance comprises a supporting member and a metal nano-dot group provided on the supporting member, metal nano-dots each of which is comprised in the metal nano-dot group and adjacent to each other are arranged with a gap between the metal nano-dots of not larger than 30 nm. | 2010-07-15 |