27th week of 2010 patent applcation highlights part 41 |
Patent application number | Title | Published |
20100174029 | SOFT POLYOLEFIN COMPOSITIONS WITH IMPROVED PROCESSABILITY - Soft polyolefin composition with improved processability comprising from 8 to 45% by weight of a polypropylene component (A), from 82 to 45% by weight of an elastomeric component (B), and from 10 to 25% by weight of a viscosity reducing agent (C) comprising polybutene-1 and paraffinic wax or grease. The composition is easily processable also by injection moulding and has better tensile properties than compositions in which processability is improved by visbreaking. | 2010-07-08 |
20100174030 | THERMOPLASTIC ARTICLES COMPRISING CYCLOBUTANEDIOL HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN - This invention relates to thermoplastic article having one or more decorative materials embedded therein which is obtained by applying heat and pressure to one or more laminates wherein at least one of said laminates comprises, in order, (1) an upper sheet material; (2) one or more decorative materials; and (3) a lower sheet material; wherein the upper and lower sheet materials are formed from a polyester/aromatic polycarbonate blend wherein the thermoplastic article comprises at least one polyester composition comprising at least one polyester which comprises terephthalic acid and 2,2,4,4-tetramethyl-1,3-cyclobutanediol. | 2010-07-08 |
20100174031 | SYNTHETIC RESIN PROCESS AND ARTICLE USEFUL FOR PLATING APPLICATIONS - A method for processing reinforcing filler-filled synthetic resins and applications made therefrom wherein the resulting articles have the ability to be plated to form a structurally aesthetic product substantially free of visual defects. The process utilizes an accelerated heat and cool process to form a resin-rich surface that is substantially free of any reinforcing fillers, such as fiber strands and/or bundles, on the external surface of the article. As such, the resulting article is capable of being plated to form an article that is substantially free of visual defects caused by these fillers on the surface of the article. | 2010-07-08 |
20100174032 | Barrier Coating Comprising a Polyurethane Dispersion and Elastomeric Material - A barrier coating comprising a polyurethane dispersion and an elastomeric material is disclosed. The polyurethane comprises at least 30 weight percent of meta-substituted aromatic material. Methods for improving barrier using the coatings are also disclosed. | 2010-07-08 |
20100174033 | THERMOPLASTIC ARTICLES COMPRISING CYCLOBUTANEDIOL HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN - This invention relates to thermoplastic article having one or more decorative materials embedded therein which is obtained by applying heat and pressure to one or more laminates wherein at least one of said laminates comprises, in order, (1) an upper sheet material; (2) one or more decorative materials; and (3) a lower sheet material; wherein the upper and lower sheet materials are formed from a polyester/aromatic polycarbonate blend wherein the thermoplastic article comprises at least one polyester composition comprising at least one polyester which comprises terephthalic acid and 2,2,4,4-tetramethyl-1,3-cyclobutanediol. | 2010-07-08 |
20100174034 | THERMOPLASTIC ARTICLES COMPRISING CYCLOBUTANEDIOL HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN - This invention relates to thermoplastic article having one or more decorative materials embedded therein which is obtained by applying heat and pressure to one or more laminates wherein at least one of said laminates comprises, in order, (1) an upper sheet material; (2) one or more decorative materials; and (3) a lower sheet material; wherein the upper and lower sheet materials are formed from a polyester/aromatic polycarbonate blend wherein the thermoplastic article comprises at least one polyester composition comprising at least one polyester which comprises terephthalic acid and 2,2,4,4-tetramethyl-1,3-cyclobutanediol. | 2010-07-08 |
20100174035 | POLYSILOXANE AND URETHANE MODIFIED WATER-REDUCIBLE ALKYD RESINS - Urethane and siloxane modified water-reducible alkyd resins ABCDE, comprising moieties derived from polyhydric alcohols A, modified fatty acids B made by grafting olefinically unsaturated carboxylic acids B2 onto fatty acids B1, ungrafted fatty acids C, silanol or alkoxysilyl functional siloxane oligomers or polymers D, and polyfunctional isocyanates E, a process for their production, and a method of use thereof in coating binders. | 2010-07-08 |
20100174036 | Preparation of polyolefin-based adhesives - Disclosed is a method for preparing polyolefin-based adhesives. In the method, a maleated polyolefin is blended, in sequence, with a polyolefin elastomer and then with a linear low density polyethylene. The polyolefin-based adhesive made according to the method of the invention shows improved clarity and adhesion in multilayer polyolefin films. | 2010-07-08 |
20100174037 | SLURRY PHASE POLYMERISATION PROCESS - A polymerisation process is disclosed in which polyethylene is produced in slurry in a polymerisation reactor in the presence of a Ziegler Natta catalyst and an activator, and slurry containing the polymer is withdrawn from the reactor and transferred to a flash tank operating at a pressure and temperature such that at least 50 mol % of the liquid component of the slurry is withdrawn from the flash tank as a vapour and at least 98 mol %, more preferably at least 98.5 mol %, and most preferably at least 99.5 mol %, of the vapour withdrawn from the flash tank is capable of being condensed at a temperature of between 15 and 40C without compression, wherein a by-product suppressor, which reduces the amount of by-product formed per unit of polyethylene produced by at least 10% compared with an identical polymerisation process where the by-product suppressor is not present, is used in the reactor. | 2010-07-08 |
20100174038 | PROCESS FOR PRODUCING SOLID CATALYST COMPONENT PRECURSOR FOR OLEFIN POLYMERIZATION - A production process is provided for an olefin polymerization catalyst component precursor, including the step of adding an organomagnesium compound to a solution containing a Si—O bond-containing silicon compound, a titanium compound represented by a defined formula, and a solvent, in an amount of 2.5 to 90 mol, per one liter of the solvent, of magnesium atoms contained in the organomagnesium compound added. Also provided are a production process of an olefin polymerization catalyst component using the above precursor; a production process of an olefin polymerization catalyst using the above catalyst component; and a production process of an olefin polymer using the above catalyst. | 2010-07-08 |
20100174039 | Catalyst system for polymerizing cyclic olefin having polar functional group, polymerizing method using the catalyst system, olefin polymer produced by the method and optical anisotropic film comprising the olefin polymer - A catalyst system capable of producing a cyclic olefin polymer having a polar functional group and a high molecular weight with a high yield in which a catalyst is not deactivated due to polar functional groups of monomers, and a method of producing polymers using the same are provided. The catalyst system for polymerization of olefin according to the present invention has good thermal and chemical stability, and thus, in the method of preparing polyolefin using the catalyst system, the deactivation of a catalyst due to a polar functional group of the monomer can be prevented, and thus a high yield of the cyclic olefin polymer with a high molecular weight can be obtained when a ratio of the catalyst to the monomer is 1:5000, and the removal of a catalyst residue is not required. | 2010-07-08 |
20100174040 | PROCESS FOR PREPARING ACRYLATE COPOLYMERS - The present invention relates to a method of producing polymers by free-radical polymerization in solution, wherein the polymerization initiator used is an ethanol-soluble initiator, and the solution polymerization is carried out in an alcoholic solvent which comprises 5 to 50% by weight of water. | 2010-07-08 |
20100174041 | SELF-HEALING POLYMERS - It has been determined that the important factors necessary for self-healing polymers include: good impact strength, control of the degree of crystallinity, low melting point (for materials shot at approximately 25° C.), and the ability to melt flow. Polymeric structures fabricated from suitable self-healing polymeric materials are also described. | 2010-07-08 |
20100174042 | AROMATIC COMPOUND AND SULFONATED POLYARYLENE POLYMER - Sulfonated polymers have excellent processability and methanol resistance. | 2010-07-08 |
20100174043 | PROCESS FOR PRODUCING ORIENTED THERMOPLASTIC RESIN FILM, APPARATUS THEREFOR AND BASE FILM FOR OPTICAL FILM - Electromagnetic waves radiated when a formed polyester film | 2010-07-08 |
20100174044 | POLYESTER RESIN, METHOD OF PRODUCING THE SAME, COMPOSITION FOR MOLDED ARTICLE AND MOLDED ARTICLE - Provide are a novel polyester resin that can be used for producing a molded article excellent in impact resistance, and a method of producing the polyester resin. The polyester resin has structural units represented by the following general formulae (1) and (2), and contains the structural unit represented by the general formula (2) at a content of 50.1 mol % or more to 99.9 mol % or less with respect to the total of the structural units represented by the general formulae (1) and (2). The method of producing a polyester resin, includes copolymerizing a furandicarboxylic acid or an ester thereof with ethylene glycol and diethylene glycol. In the formula, R | 2010-07-08 |
20100174045 | NONTOXIC POLYETHOXYSILOXANE MATERIAL OR THE PRODUCTION OF BIOLOGICALLY RESORBABLE AND OR BIOACTIVE ARTICLES CONTAINING POLYETHOXYSILOXANE MATERIAL, THE PRODUCTION THEREOF, AND THE USE THEREOF - The present invention relates to a polyethoxysiloxane (PES) material to be obtained in that (a) a first hydrolysis condensation reaction of a maximum of one group X of one or more different Si compounds of the formula (I) SiX4 (I) in which the groups X are the same or different and represent hydroxy, hydrogen, or ethoxy (EtO), are catalyzed in an acidic fashion at an initial pH value of 0 to ≦7, is conducted in the presence of ethanol (EtOH) or an ethanol-water mixture as a solvent over a time period of 1 to 24 hours at a temperature of 0° C. to 78° C., (b) a second hydrolysis condensation reaction of the material obtained in step (a) is conducted while simultaneously removing the solvent by successive evaporation in a gas diffusion-tight container at a pressure of 100 to 1013 mbar, preferably at a slight negative pressure of 300 mbar to 800 mbar and a temperature of 50-78° C. until a drastic increase in viscosity (at a shear rate of 10 s | 2010-07-08 |
20100174046 | POLYETHYLENE IMINE BASED PIGMENT DISPERSANTS - This invention refers to a novel process for the synthesis of polyethylene imine (PEI)-based pigment dispersants characterized by a “grafting from” approach, allowing the manufacture of solvent based dispersant systems. The polyethylene imine (PEI)-based pigment dispersant can be presented by the formula (I) X-(T) | 2010-07-08 |
20100174047 | Coordination Polymer Crystal With Porous Metal-Organic Frameworks and Preparation Method Thereof - Disclosed is a coordination polymer crystal with porous metal-organic frameworks (MOFs), in which, while a crystal state of the coordination polymer crystal is maintained, an additional material selected from the group consisting of an organic compound, a metal cluster, and an organometallic compound is chemically bonded to the coordination polymer crystal. Therefore it is possible easily adsorb and store more guest molecules regardless of a change in an ambient temperature or pressure due to the chemically bonded additional material. | 2010-07-08 |
20100174048 | Processes for Preparing a Polypeptide - The present invention relates to an improved process for preparing a polypeptide or pharmaceutically acceptable salt thereof comprising L-tyrosine, L-alanine, L-glutamate, and L-lysine. The polypeptide or pharmaceutically acceptable salt thereof is preferably glatiramer acetate. The process comprises: (a) polymerizing a mixture of N-carboxyanhydride of L-tyrosine, N-carboxyanhydride of L-alanine, N-carboxyanhydride of a protected L-glutamate and N-carboxyanhydride of a protected L-lysine, in a polar aprotic solvent in the presence of an initiator, to form a protected polypeptide; (b) admixing an acid with the protected polypeptide formed in Step (a) and a solvent, to form a product; and (c) admixing a substance selected from the group consisting of an alkali or alkaline earth metal hydroxide, a carbonate, a hydrogencarbonate, and mixtures thereof, with the product formed in Step (b), and a solvent or a mixture of a solvent and water, to form a deprotected polypeptide or a pharmaceutically acceptable salt thereof. | 2010-07-08 |
20100174049 | Reversed mammalian protein-protein interaction trap - The invention relates to a recombinant receptor, comprising a ligand-binding domain and a signaling domain that comprises a heterologous bait polypeptide, which receptor is inactivated by binding of a prey polypeptide to the heterologous bait peptide, either in presence or absence of a ligand binding to the ligand-binding domain. The receptor is activated by addition of a compound that disrupts the bait-prey interaction. The invention also relates to a method of screening compounds that disrupt compound-compound binding using the recombinant receptor. | 2010-07-08 |
20100174050 | EXPRESSION OF POLYPEPTIDES FROM THE NUCLEAR GENOME OF OSTREOCOCCUS SP - A method of producing at least one polypeptide from the nuclear genome of | 2010-07-08 |
20100174051 | Asymmertric porous adsorptive bead - The present invention relates to an asymmetric chromatography media suitable for separations applications, particularly as packed bed, fluidized bed or magnetized bed chromatography media. In certain embodiments, the asymmetric chromatography media comprises asymmetric particles, preferably beads, having at least two distinct, controlled pore size distributions. Preferably one of the distinct pore size distributions is in an internal region of the particle, and the other is in an external region or coating on the particle. These distinct pore size distributions can be modified with uniform or alternatively unique functional groups or mixtures of functional groups. The present invention allows for the control over pore size distribution within an asymmetric porous particle by providing a distinct internal region, preferably in the form of a bead, and a distinct external region, preferably in the form of a coating on the bead. | 2010-07-08 |
20100174052 | SEPARATION METHOD USING POLYMER MULTI PHASE SYSTEMS - The present invention relates to a process of isolating one or more target compounds, wherein the clarification of feed is performed using partitioning in a multiphase system comprising a first polymer, which is a synthetic poly(acid), a second synthetic polymer, which is a poly(ether), and at least one salt, which clarification is followed by at least one step of affinity chromatography. The molecular weight of the poly(acid) may be in the range of 1000-100,000 Da. The target compound is preferably a biomolecule, such as a monoclonal antibody. | 2010-07-08 |
20100174053 | COVALENT DIABODIES AND USES THEREOF - The present invention is directed to diabody molecules and uses thereof in the treatment of a variety of diseases and disorders, including immunological disorders, infectious disease, intoxication and cancers. The diabody molecules of the invention comprise two polypeptide chains that associate to form at least two epitope binding sites, which may recognize the same or different epitopes on the same or differing antigens. Additionally, the antigens may be from the same or different molecules. The individual polypeptide chains of the diabody molecule may be covalently bound through non-peptide bond covalent bonds, such as, but not limited to, disulfide bonding of cysteine residues located within each polypeptide chain. In particular embodiments, the diabody molecules of the present invention further comprise an Fc region, which allows antibody-like functionality to engineered into the molecule. | 2010-07-08 |
20100174054 | Compositions of Aminoacyl-tRNA Synthetase and Uses Thereof - Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNA's/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs. | 2010-07-08 |
20100174055 | ASSAY FOR BCR/ABL GENE REARRANGEMENT - The present invention provides a simple high-throughput assay for detecting bcr/abl translocations. The method includes qualitative PCR methods for identifying the particular amplified translocation (e1a2 or b2a3/b3a2) and real time PCR for quantifying an amount of bcr/abl transcript (e1a2, b2a3 and b3a2). Quantitative measurement of ber/abl transcript in accordance with the methods of the invention is useful for monitoring response to therapy. | 2010-07-08 |
20100174056 | RECOMBINANT TUMOR SPECIFIC ANTIBODY AND USE THEREOF - The invention provides a family of antibodies that specifically bind the human epithelial cell adhesion molecule. The antibodies comprise modified variable regions, more specially, modified framework regions, which reduce their immunogenicity when administered to a human. The antibodies, when coupled to the appropriate moiety, may be used in the diagnosis, prognosis and treatment of cancer. | 2010-07-08 |
20100174057 | DENGUE SEROTYPE 2 ATTENUATED STRAIN - The invention relates to live attenuated VDV2 (VERO-Derived Vaccine Dengue serotype 2) strains which have been derived from the wild-type dengue-2 strain 16681 by passaging on PDK and Vero cells and nucleic acids thereof. The invention further relates to a vaccine composition which comprises a VDV2 strain. | 2010-07-08 |
20100174058 | FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS - Oligonucleotide probes containing two labels are provided and are useful in hybridization assays. The probes can also contain a minor groove binding group. | 2010-07-08 |
20100174059 | PROCESS FOR THE PRODUCTION OF NUCLEOTIDE SUGARS - The current invention provides methods (e.g., large-scale processes) for the production of nucleotide sugars, which are modified with a polymeric modifying group, such as poly(alkylene oxide) moieties (e.g., poly(ethylene glycol) or poly(propylene glycol)) moieties. A typical process of the invention includes anion exchange chromatography followed by an ultrafiltration procedure, such as tangential flow filtration. The process of the invention provides modified nucleotide sugars in unexpectedly high purity and high overall yields. | 2010-07-08 |
20100174060 | LYOCELL FIBER FOR TIRE CORD AND TIRE CORD COMPRISING THE SAME - The present invention relates to a lyocell fiber having superior the crystalline properties, which are measured by wet-treated and dry-treated condition under high temperature and high pressure conditions compared to measurement under standard conditions, and to a tire cord comprising the lyocell fiber. According to the present invention, the lyocell fiber has strength, elongation, and modulus that are superior to those of a conventional rayon, even when the lyocell fiber is wet- and dry-treated under high temperature and high pressure conditions by specifying water-washing conditions of a spinning machine, thereby improving dimensional stability of a tire cord when it is applied to the tire cord. | 2010-07-08 |
20100174061 | PLANTS WHICH SYNTHESIZE A MODIFIED STARCH, PROCESS FOR THE PRODUCTION THEREOF AND MODIFIED STARCH - Nucleic acid molecules are described encoding a starch granule-bound protein as well as methods and recombinant DNA molecules for the production of transgenic plant cells and plants synthesizing a modified starch with modified viscosity properties and a modified phosphate content. Moreover, the plant cells and plants resulting from those methods as well as the starch obtainable therefrom are described. | 2010-07-08 |
20100174062 | MODIFIED XANTHAN GUM, MODIFIED GUM ARABIC, AND MODIFIED TAMARIND SEED GUM, AND METHODS FOR CROSSLINKING XANTHAN GUM, GUM ARABIC, AND TAMARIND SEED GUM - An object is to provide a modified xanthan gum, a modified gum arabic, and a modified tamarind seed gum produced by crosslinking a naturally occurring polysaccharide such as xanthan gum, gum arabic, or tamarind seed gum, by irradiating them with radiation, and methods for crosslinking xanthan gum, gum arabic, and tamarind seed gum. | 2010-07-08 |
20100174063 | Polysaccharide Produced by Microorganism Belonging to Genus Bifidobacterium - A polysaccharide comprising galactose, glucose, rhamnose, and pyruvic acid as constituents, wherein the galactose, glucose, and rhamnose are contained in a molar ratio of 4:2:1, and the pyruvic acid is contained in an amount of 4 to 7 wt %. The polysaccharide can be obtained by culturing | 2010-07-08 |
20100174064 | FORMS OF RIFAXIMIN AND USES THEREOF - The present invention relates to Rifaximin polymorphic forms, to their use in medicinal preparations and to therapeutic methods using them. | 2010-07-08 |
20100174065 | COMPOUNDS - The present invention relates to novel oxadiazole derivatives having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders. | 2010-07-08 |
20100174066 | PROCESS FOR PREPARING CRYSTALLINE FORM I OF OLANZAPINE - A process for preparing olanzapine Form I comprises: a) cooling a concentrated solution of olanzapine; b) isolating wet crystals of olanzapine Form I; and c) drying wet crystals and recovering olanzapine Form 1. Drying can be conducted by stepwise increases in the drying temperatures, with extended holding times at each temperature condition. | 2010-07-08 |
20100174067 | Method for Producing Scopine Esters - The invention relates to a novel method for producing scopine esters of the general formula (1), wherein X—, R, R1, R2, R3, R4, R3′, R4′, R6 and R6′ can have the meanings indicated in the claims and in the description. | 2010-07-08 |
20100174068 | Complex of Ruthenium and Osmium, Method of Production Thereof and Use Thereof As (Pre)Catalysts of the Metathesis Reaction - Complexes of ruthenium and osmium according to the invention are represented by formula (1), in which M denotes ruthenium or osmium, L denotes a neutral ligand selected from the group comprising amines, imines, phosphines (preferably stilbines, arsines, alcohols, thiols, ethers and thioethers or an N-heterocyclic carbene (NHC) ligand). The compounds of formula (1) occur in the form of two isomers: trans and cis. The method of production of complexes of ruthenium and osmium of formula (1) according to the invention is based on reacting an intermediate of formula (5) with a carbene complex of ruthenium or osmium. The invention also relates to the use of the complexes according to the invention for carrying out metathesis reactions. | 2010-07-08 |
20100174069 | LIGHT-EMITTING MATERIAL COMPRISING ORTHOMETALATED IRIDIUM COMPLEX, LIGHT-EMITTING DEVICE, HIGH EFFICIENCY RED LIGHT-EMITTING DEVICE, AND NOVEL IRIDIUM COMPLEX - A light-emitting material comprising a compound having a partial structure represented by following formula (21) or a tautomer thereof: | 2010-07-08 |
20100174070 | LIGHT-EMITTING MATERIAL COMPRISING ORTHOMETALATED IRIDIUM COMPLEX, LIGHT-EMITTING DEVICE, HIGH EFFICIENCY RED LIGHT-EMITTING DEVICE, AND NOVEL IRIDIUM COMPLEX - A compound represented by following formula (23): | 2010-07-08 |
20100174071 | LIGHT-EMITTING MATERIAL COMPRISING ORTHOMETALATED IRIDIUM COMPLEX, LIGHT-EMITTING DEVICE, HIGH EFFICIENCY RED LIGHT-EMITTING DEVICE, AND NOVEL IRIDIUM COMPLEX - A synthesis method of a compound having a partial structure represented by following formula (21) or a tautomer thereof, the method comprising reacting at least one of a ligand and a dissociation product thereof with an iridium compound at a room temperature or at an elevated temperatures in the presence or absence of a solvent or in the presence or absence of a base: | 2010-07-08 |
20100174072 | SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS - The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib. | 2010-07-08 |
20100174073 | PROCESS FOR THE PREPARATION OF ALFUZOSIN AND SALTS THEREOF - The present invention relates to novel N-[3-[(4-acyl-/aroyl-substituted amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furancarboxamide derivatives, and a process for the preparation thereof. The novel compounds are useful for preparing alfuzosin or a pharmaceutically acceptable salt thereof in high yield and purity. | 2010-07-08 |
20100174074 | NOVEL BENZOPHENONE HYBRIDS AS POTENTIAL ANTICANCER AGENTS AND A PROCESS FOR THE PREPARATION THEREOF - Disclosed herein are benzophenone hybrids with potent anticancer activities and processes for creation of the same. | 2010-07-08 |
20100174075 | USE OF NITRIC OXIDE-RELEASING STATINS IN THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION - The present invention relates to the use of nitric oxide-releasing statins of formula (I) for the treatment of pulmonary arterial hypertension. | 2010-07-08 |
20100174076 | COUMARIN DERIVATIVES USEFUL AS TNF ALPHA INHIBITORS - Novel compounds composition capable of inhibiting TNFα and having antiimmunionflammatory and autoimmune properties useful in a pharmaceutical composition, such as for a drug containing this as an active ingredient; and a therapeutic method with the use of these novel compounds. | 2010-07-08 |
20100174077 | Processes and intermediates - The invention relates to compounds and processes useful for the preparation of protease inhibitors, particularly serine protease inhibitors. The protease inhibitors are useful for treatment of HCV infections. | 2010-07-08 |
20100174078 | Bipyridine metal complexes for use as light-emitting material - The present invention relates to light emitting materials comprising novel ortho-metalated transition metal complexes [ĈN] | 2010-07-08 |
20100174079 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PHOSPHOROUS COMPOUND - Disclosed is a process for producing an optically active phosphorus compound having an R- or S-type absolute configuration on phosphorus in a simple manner and at high efficiency, while avoiding racemization. | 2010-07-08 |
20100174080 | NOVEL PALONOSETRON SALTS AND PROCESSES FOR PREPARATION AND PURIFICATION THEREOF - Provided are novel salts of 2-(1-azabicyclo-[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one, methods of using such salts, and processes for producing such salts | 2010-07-08 |
20100174081 | PRODUCTION PROCESS OF OPTICALLY ACTIVE 3-QUINUCLIDINOL DERIVATIVE - A process is provided for efficiently producing an optically active 3-quinuclidinol derivative of high optical purity using a readily available ruthenium compound as an asymmetric reduction catalyst. This process is a process for producing an optically active 3-quinuclidinol derivative represented by the following formula (III) comprising asymmetrically hydrogenating a 3-quinuclidinone derivative represented by the following formula (I) in the presence of a ruthenium compound (II) represented by formula (II): Ru(X)(Y)(Px) | 2010-07-08 |
20100174082 | (1R,1'R)-ATRACURIUM SALTS SEPARATION PROCESS - The present invention provides an improved method for obtaining cisatracurium besylate, which preferably chromatographically separating cisatracurium besylate from a mixture of (1R,1′R)-atracurium isomers via flash chromatography | 2010-07-08 |
20100174083 | METHOD FOR THE PREPARATION OF MONTELUKAST - A method of preparation of Montelukast of formula (I) by reaction of the compound of formula (III) and a compound of formula (IX), characterized in that the reaction is carried out in the presence of a base, an inert solvent and a component increasing selectivity of the process, especially of a polyether of general formula (XIII), wherein R stands for hydrogen or an alkyl and the value of n varies from 1 to 40, polyethyleneglycol of general formula (XIV), wherein n=1 to 40 or a crown-ether of formulae (XV), (XVI) or (XVII). | 2010-07-08 |
20100174084 | 2-Alkoxy-6-alkyl-phenyl-substituted Spirocyclic Tetramic Acid Derivatives - The invention relates to novel 2-alkoxy-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives of the formula (I) | 2010-07-08 |
20100174085 | CRYSTALLINE POLYMORPHIC FORMS OF FEXOFENADINE - The present invention is related to a novel polymorph of Fexofenadine and processes of preparation thereof. | 2010-07-08 |
20100174086 | ELECTRON-TRANSPORTING MATERIALS AND PROCESSES FOR MAKING THE SAME - Compound of formula C is made by reacting a compound of formula A with an pyridyl boronic acid or pyridyl borate ester to form a compound of formula B; and | 2010-07-08 |
20100174087 | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE ESOMEPRAZOLE - The present invention provides an improved and commercially viable process for preparation of substantially enantiomerically pure esomeprazole in neutral form or as a pharmaceutically acceptable salt or as its solvates including hydrates. Thus, for example, a compound containing a mixture of 1-(S)-camphorsulfonyl-5-methoxy-2-[(3,5-dimethyl-4-methoxy-2-pyridyl)methyl-(S)-sulfinyl]-1H-benzimidazole and 1-(S)-camphorsulfonyl-6-methoxy-2-[(3,5-dimethyl-4-methoxy-2-pyridyl)methyl-(S)-sulfinyl]-1H-benzimidazole is hydrolyzed with barium hydroxide, isolated the resulting esomeprazole barium salt followed by neutralization with an acid to yield substantially enantiomerically pure esomeprazole in neutral form and then converted into its pharmaceutically acceptable salts. | 2010-07-08 |
20100174088 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOL THIENYLAMINE COMPOUNDS AND DERIVATIVES THEREOF USEFUL AS SODIUM/PROTON EXCHANGER TYPE 3 INHIBITORS - The present invention is an improved process for the preparation of a sodium/proton exchange inhibitor of sub-type 3 (NHE-3) useful in the treatment of sleep apnea and other related respiratory disorders. The improved synthesis of the NHE-3 inhibitor, more specifically a benzimidazol thienylamine, utilizes novel reagents and chemical intermediates and thereby results in an improved yield and purity of the final product with less reaction or synthetic steps required | 2010-07-08 |
20100174089 | HETEROARYL ARYL ETHERS - The present invention relates to a process for the preparation of optionally substituted heteroaryl aryl ethers, in particular of phenoxypyridines. | 2010-07-08 |
20100174090 | METHODS OF PREPARING PRIMARY, SECONDARY AND TERTIARY CARBINAMINE COMPOUNDS IN THE PRESENCE OF AMMONIA - The present application relates to novel methods for the preparation of primary, secondary and tertiary carbinamine compounds, particularly the preparation of compounds of formulae I, IV and VI, from a carbonyl compound of formula II in the presence of ammonia or an ammonium equivalent of the formula NH | 2010-07-08 |
20100174091 | Process for the preparation of tetrazolytetrahydrocyclopentapyrazoles - A process for the preparation of a compound of formula (I), or a salt, hydrate or solvate thereof; wherein R | 2010-07-08 |
20100174092 | NOVEL 5 SUBSTITUTED HYDANTOINS - The present invention relates to 5-substituted hydantoins, a process for the preparation of 5-substituted hydantoins and the use of 5-substituted hydantoins in the preparation of enantiomerically enriched α-amino acids. Furthermore, the present invention relates to the preparation of pharmaceutically active products such as perindopril and ramipril using the novel 5-substituted hydantoins. | 2010-07-08 |
20100174093 | PROCESS FOR THE PRODUCTION OF PYRAZOLES - A process for the production of a compound of formula (I), which comprises a) reacting a compound of formula (II), wherein R | 2010-07-08 |
20100174094 | Method for the Production of N-Substituted (3-Dihalomethyl-1-Methyl-Pyrazole-4-yl) Carboxamides - The present invention relates to a process for preparing N-substituted (3-dihalomethylpyrazol-4-yl)carboxamides of the formula (I) | 2010-07-08 |
20100174095 | ORGANIC COMPOUND, SEMICONDUCTOR FILM ELECTRODE EMPLOYING THE ORGANIC COMPOUND, PHOTOELECTRIC CONVERSION ELEMENT EMPLOYING THE ORGANIC COMPOUND, AND PHOTOELECTROCHEMICAL SOLAR CELL EMPLOYING THE ORGANIC COMPOUND - The present invention provides: an organic compound increasing an open circuit voltage, and showing high photoelectric conversion efficiency; a semiconductor film electrode employing the organic compound as a dye; a photoelectric conversion element employing the semiconductor film electrode; and a photoelectrochemical solar cell employing the photoelectric conversion element. The organic compound is represented by the following general formula: | 2010-07-08 |
20100174096 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives - Useful industrial methods for producing optically active fluoropyrrolidine derivatives as useful fluorinated intermediates are disclosed. | 2010-07-08 |
20100174098 | 3-ETHYLOXETHANE COMPOUND HAVING HYDROXYL GROUP AND METHOD FOR PRODUCING THE SAME - Disclosed is a 3-ethyloxethane compound having a hydroxyl group which is represented by the following general formula (1). (1) (In the formula, A represents an alkylene group having 3-5 carbon atoms which may have an ether bond or an alkylene group having 3-5 carbon atoms which may be substituted by a hydroxyl group.) The 3-ethyloxethane compound having a hydroxyl group can be produced by reacting a 3-ethyloxethane compound represented by the general formula (2) below, a diol compound represented by the general formula (3) below and a base. (2) (In the formula, X represents a leaving group.) (3) (In the formula, A is as defined above.) | 2010-07-08 |
20100174099 | Propylene oxide reactor gas distribution system - A device for reacting fluids comprising:
| 2010-07-08 |
20100174100 | METHOD FOR PRODUCING PROPYLENE OXIDE - A method is for producing propylene oxide, including reacting propylene, hydrogen, and oxygen, in an acetonitrile solvent or in a mixture of solvents which include acetonitrile and water, in presence of a titanosilicate catalyst and a palladium catalyst supported on a carrier, the propylene being fed into the reaction in the form of liquefied propylene. This realizes efficient production of propylene oxide. | 2010-07-08 |
20100174101 | Process for the manufacture of 7-alpha-[9-(4,4,5,5,5-penta fluoropentylsulphinyl) nonyl]estra-1,3,5-(10)- triene-3,17-beta-diol - The present invention provides a novel multi-step process for the manufacturing Fulvestrant, which is economical and convenient to operate at commercial scale, and requires only simple chromatographic separations after the coupling step of adding the side chain to the 7 position of the steroid. | 2010-07-08 |
20100174102 | PROCESS FOR THE PREPARATION OF AN OXALIPLATIN - The present invention relates to an improved process for the preparation of oxaliplatin, the obtained oxaliplatin preparation and its use in cancer therapy. | 2010-07-08 |
20100174103 | MATERIAL FOR FORMING SILICON-CONTAINING FILM, AND SILICON-CONTAINING INSULATING FILM AND METHOD FOR FORMING THE SAME - A silicon-containing film-forming material includes at least one organosilane compound shown by the following general formula (1). | 2010-07-08 |
20100174104 | COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES - Asymmetric cyclopropanation of olefins with diazosulfones. | 2010-07-08 |
20100174105 | Production of Substituted Phenylene Aromatic Diesters - The present disclosure is directed to the production of 5-tert-butyl-3-methyl-1,2-phenylene dibenzoate and the purification thereof. Synthesis pathways for a precursor to 5-tert-butyl-3-methyl-1,2-phenylene dibenzoate are provided. The precursor is 5-tert-butyl-3-methylcatechol. | 2010-07-08 |
20100174106 | HETEROGENEOUS ORGANOTIN CATALYSTS - Supported heterogeneous organotin catalysts of the formula X1, X2, or X3: | 2010-07-08 |
20100174107 | ACCELERATED SYNTHESIS OF SUBSTITUTED HYDROXYMETHYL PHENOLS - This disclosure relates to process for the preparation of a compound of formula (I) wherein R is hydrogen, a straight or branched C | 2010-07-08 |
20100174108 | PROCESS FOR THE SEPARATION OF PROBUCOL DERIVATIVES - Provided are methods for the separation of mono-substituted probucol derivatives from a mixture of both mono- and di-substituted probucol derivatives. In particular, methods are provided for the separation of mono-carboxy substituted probucol derivatives from a mixture of mono- and di-carboxy substituted probucol derivatives. | 2010-07-08 |
20100174109 | METHOD FOR PRODUCING ETHYLENICALLY UNSATURATED GROUP-CONTAINING ISOCYANATE COMPOUND HAVING ETHER BOND - To provide a method for producing an ethylenically unsaturated group-containing isocyanate compound having an ether bond under such conditions that the ether bond is unlikely to be cleaved and the polymerization of an unsaturated group can be suppressed. The method for producing an ethylenically unsaturated group-containing isocyanate compound having an ether bond of the present invention is a method for producing an ethylenically unsaturated double bond-containing isocyanate compound from an amino alcohol having an ether bond and is characterized in that a reaction solvent in which the solubility of hydrogen chloride is 0.1 mole percent or less at 25° C. is used. | 2010-07-08 |
20100174110 | PROCESS FOR THE MANUFACTURE OF ALKYLAMINO ALKYLENE PHOSPHONIC ACIDS - A process for the manufacture of alkylamino alkylene phosphonic acids is disclosed. In detail, a specific phosphonate is reacted with an agent selected to yield an alkylamino moiety substituted by a radical selected from OH, OR′, NH2, NHR′, N(R′) | 2010-07-08 |
20100174111 | PROCESS FOR PURIFICATION OF ARYL CARBOXYLIC ACIDS - Disclosed herein is a process for purifying aryl carboxylic acids, in particular terephthalic acid, wherein the impure acid is dissolved or dispersed in an ionic liquid and a non-solvent is added to precipitate the purified acid. The present disclosure further relates to compositions comprising terephthalic acid and one or more ionic liquids. | 2010-07-08 |
20100174112 | PROCESS FOR PRODUCING ACRYLIC ACID - A process which enables production of acrylic acid on an industrial scale at high productivity with stability, comprising production of acrylic acid by oxidation of propane with molecular oxygen, is provided. The process is characterized in characterized by re-use of the gas containing unreacted propane, as obtained after recovering acrylic acid from the gas produced of the reaction, as a recycling gas after removing at least a part of carbon dioxide from the same gas. | 2010-07-08 |
20100174113 | AROMATIC SULPHONYLIMIDES, PREPARATION THEREOF AND USE THEREOF AS ELECTROLYTE - The invention relates to a process for preparing aromatic sulphonylimides, to the sulphonylimides obtained, and to the use thereof as salt of an electrolyte. The sulphonylimides correspond to the formula [R—SO | 2010-07-08 |
20100174114 | PROCESS FOR THE PREPARATION OF DI- AND POLYAMINES OF THE DIPHENYLMETHANE SERIES - The present invention relates to a process for the preparation of di- and polyamines of the diphenylmethane series, and to the preparation of di- and polyisocyanates of the diphenylmethane series from these di- and polyamines. The di- and polyamines of the diphenylmethane series are prepared by the reaction of aniline and formaldehyde in the presence of hydrochloric acid. In the present invention, the formaldehyde employed is used as an aqueous solution which contains less than 0.001 wt % of metal ions which are divalent and/or more than divalent. | 2010-07-08 |
20100174115 | TETRAMINE COMPOUND AND ORGANIC EL DEVICE - The present invention provides a method for producing a tetramine compound represented by formula (1): | 2010-07-08 |
20100174116 | Activated Base Metal Catalysts - Nitro-compounds are hydrogenated with an activated Ni catalyst that is doped during and/or after activation with one or more elements from the list of Mg, Ca, Ba, Ti, Zr, Ce, Nb, Cr, Mo, W, Mn, Re, Fe, Co, Ir, Ni, Cu, Ag, Au, Rh, Ru and Bi whereas the Ni/Al alloy may not, but preferentially can contain prior to activation one or more doping elements from the list of Ti, Ce, V, Cr, Mo, W, Mn, Re, Fe, Ru, Co, Rh, Ir, Pd, Pt and Bi. If the Ni/Al alloy contained one or more of the above mentioned suitable alloy doping elements prior to activation, the resulting catalyst can then be doped with one or more of the elements from the list of Mg, Ca, Ba, Ti, Zr, Ce, V, Nb, Cr, Mo, W, Mn, Re, Fe, Ru, Co, Rh, Ir, Ni, Pd, Pt, Cu, Ag, Au and Bi by their adsorption onto the surface of the catalyst. | 2010-07-08 |
20100174117 | METHOD FOR PRE-TREATING HYDROAMINATION CATALYSTS - The present invention relates to a process for the pretreatment of hydroamination catalysts, wherein the hydroamination catalyst is brought into contact with an ammonia-comprising mixture before the reaction of olefins with ammonia, a primary or secondary amine, with the ammonia-comprising mixture comprising less than 40% by weight of olefin | 2010-07-08 |
20100174118 | PROCESS FOR PRODUCTION OF CAROTENOID - A method for producing a composition containing carotenoid at a content of 80% or greater, characterized in performing extraction on a culture of a microorganism, a concentrate of the culture, or a dried substance thereof with at least one selected from the group consisting of lower alcohols, water-containing lower alcohols, lower dialkylketones and ethers; and then washing a precipitate, obtained by concentrating the extract solution, with at least one selected from the group consisting of lower alcohols, water-containing lower alcohols, hydrocarbon-based solvents and lower dialkylketones; and food, a pharmaceutical composition or a cosmetic substance comprising the carotenoid-containing composition. | 2010-07-08 |
20100174119 | PROCESS FOR THE PREPARATION OF ALDEHYDES - The present invention is related to a method for the production of an aldehyde by reducing an ester of a carboxylic acid with H-DIBAL (diisobutylaluminium hydride). | 2010-07-08 |
20100174120 | PROCESSES FOR MAKING DIBUTYL ETHERS FROM ISOBUTANOL - Processes for preparing dibutyl ethers from isobutanol using an ionic liquid. | 2010-07-08 |
20100174121 | PRODUCTION OF BUTENES AND DERIVATIVES THEREFROM FROM DRY ETHANOL - The present invention relates to the production of butenes and derivatives thereof from dry ethanol, optionally obtained from a fermentation broth. The butenes thus produced find use as intermediates for the production of polyethylenes and other materials. | 2010-07-08 |
20100174122 | PROCESS FOR PRODUCTION OF HALOGEN-SUBSTITUTED BENZENEDIMETHANOL - A process for the production of a halogen-substituted benzenedimethanol represented by the formula (2): | 2010-07-08 |
20100174123 | PREPARATION OF HYDROFLUOROOLEFINS BY DEHYDROFLUORINATION - A dehydrofluorination process is disclosed for making hydrofluoroolefins of the structure R | 2010-07-08 |
20100174124 | PROCESS AND APPARATUS EMPLOYING MICROCHANNEL PROCESS TECHNOLOGY - This invention relates to a process for conducting a hydrocracking or a hydrotreating process in a microchannel reactor. This invention also relates to a process and apparatus for flowing a vapor and liquid into a plurality of microchannels in a microchannel processing unit. | 2010-07-08 |
20100174125 | FLUIDIZED CATALYTIC CRACKER WITH ACTIVE STRIPPER AND METHODS USING SAME - A staged fluidized catalytic cracker and method for cracking a hydrocarbonaceous material includes a plurality of staged reactors that have catalyst particles flowing in series from one reactor to the next and hydrocarbon feed that is delivered in parallel to the reactors. Between each reactor the partially spent catalyst is actively stripped to partially reactivate the catalyst. Once the catalyst is fully spent in the final reactor the catalyst can be oxidatively regenerated. | 2010-07-08 |
20100174126 | OLIGOMERIZATION PROCESS - A process for oligomerization of isobutene, the process including: feeding a hydrocarbon stream comprising n-butane, 1-butene, 2-butene, isobutane, and isobutene to a catalytic distillation reactor system comprising a hydroisomerization catalyst; feeding hydrogen to the catalytic distillation reactor system; concurrently in the catalytic distillation reactor system: contacting the 1-butene with the hydrogen in the presence of the hydroisomerization catalyst to convert at least a portion of the 1 -butene to 2-butene; separating the isobutane and the isobutene from the n-butane and the 2-butene; recovering the isobutane and the isobutene from the catalytic distillation reactor system as an overheads fraction; recovering the n-butane and the 2-butene from the catalytic distillation reactor system as a bottoms fraction; contacting the overheads fraction in an oligomerization reaction system with an oligomerization catalyst to convert a portion of the isobutene to oligomers. | 2010-07-08 |
20100174127 | Converaion of ethanol broth to LPG and gasoline - A process for converting a dilute ethanol solution to liquid hydrocarbon fuels such as LPG and gasoline by preferentially driving-off the ethanol molecules in the solution across the liquid-air interface and streaming same into a heating and catalytic reacting system maintained at the conversion conditions. The concentration of the dilute ethanol solutions are in the range of from 5% to 15% ethanol and the reacting system comprises a zeolite type of catalyst such as ZSM-5. | 2010-07-08 |
20100174128 | Butane Absorption System for Vent Control and Ethylene Purification - The present invention describes a n-butane absorption process for purifying the ethylene product from an ethane oxidation process. The ethane oxidation product is fed to a series of absorption towers using a n-butane solvent that remove the inert components as well as purifying the ethylene from the product. A first absorption tower uses n-butane as a solvent to absorb both the ethane and ethylene, allowing for inert gasses to be removed from the stream. An ethylene-rich side stream from this tower is sent to an ethylene purification tower where ethylene is purified using n-butane solvent. The bottom stream from the first absorption tower is then sent to an intermediate ethylene recovery tower where crude ethylene is purified, and the overhead ethylene stream being sent to the ethylene purification tower. The bottoms stream, along with the bottoms stream of the ethylene purification tower, both of which comprise mostly ethane and n-butane, are then sent to a stripper tower for ethane recovery and n-butane solvent recover. | 2010-07-08 |
20100174129 | HIGH THROUGHPUT PROPYLENE FROM METHANOL CATALYTIC PROCESS DEVELOPMENT METHOD - A catalytic process development apparatus and method for simulating a commercial scale methanol and/or DME to propylene catalytic conversion system that includes a plurality of series-connected plug-flow reactors. The method involves simulating the operation of the series-connected plug-flow reactors by operating a series of multistage series-connected laboratory scale plug-flow reactors, the stages of which each containing a zeolite catalyst bed, each of the laboratory scale reactors corresponding to a separate one of the commercial scale series-connected reactors. Fresh feed, including methanol and/or DME, is supplied to the first of the laboratory scale reactor stages, and selected ones of steam, methanol and/or DME, contaminants and reaction products are supplied to selected ones of the laboratory scale reactor stages. The simulation is repeated at different sets of operating conditions and catalyst characteristics. | 2010-07-08 |