27th week of 2010 patent applcation highlights part 33 |
Patent application number | Title | Published |
20100173227 | Polymer-Electrolyte Fuel Cell - Fuel cell comprising a stack of bipolar plates ( | 2010-07-08 |
20100173228 | Nanotube and Carbon Layer Nanostructured Composites - The present invention relates to nanostructured composites comprising a nanotube network which is at least partially embedded within a carbon layer. The present invention particularly relates to conducting nanostructured composites for use in the fields of energy conversion, energy storage and also the biomedical field. The present invention also relates to a process via CVD of carbon onto a catalyst layer on a substrate. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. | 2010-07-08 |
20100173229 | SHRINKABLE LABEL HAVING A HOLOGRAM LAYER AND CONTAINER WITH THE LABEL - Provided is a shrinkable label having a hologram layer that suffers no whitening even after shrink processing with relatively large shrinkage. The label therefore fits even complicated dimensions of an article and, in addition, provides a superior holographic expression. | 2010-07-08 |
20100173230 | PHOTOMASK - A photomask or equivalent optical component includes a scattering element in the medium of a substrate, which actively modifies (adjusts/filters the intensity, shape, and/or components of) light that propagates through the substrate. The substrate has a front surface and a back surface and is transparent to exposure light of a photolithography process, i.e., light of given wavelength, at least one mask pattern at the front surface of the substrate and the image of which is to be transferred to an electronic device substrate in a photolithographic process using the photomask, a blind pattern at the front surface of the substrate and opaque to the exposure light, and the scattering element. The scattering element, in addition to being formed in the medium of the substrate, is situated below the blind pattern as juxtaposed with the blind pattern in the direction of the thickness of the substrate. Also, a section of the photomask substrate is irradiated with energy which does not melt and/or vaporize the medium of the photomask substrate to form the scattering element. To this end, a femtosecond laser may be used. | 2010-07-08 |
20100173231 | LCD DEVICE INCLUDING A REFLECTION FILM HAVING A CONVEX-CONCAVE SURFACE - An LCD device includes a reflective area in each pixel. A reflection film having a convex-concave surface is provided in the reflective area, film in cross section configuration is formed. Each pixel includes a pixel electrode and a common electrode for applying a lateral electric field on a LC layer. The inclination angle of the reflection film has an inclination angle distribution, wherein the angle component in an area corresponding to the electrodes has a lower angle distribution than the angle components in an area corresponding to a gap between adjacent two of the electrodes. | 2010-07-08 |
20100173232 | MASK BLANK PROVIDING SYSTEM, MASK BLANK PROVIDING METHOD, MASK BLANK TRANSPARENT SUBSTRATE MANUFACTURING METHOD, MASK BLANK MANUFACTURING METHOD, AND MASK MANUFACTURING METHOD - A mask blank manufacturing department manufactures a mask blank by forming a thin film to be a mask pattern on a mask blank transparent substrate. When providing the mask blank to a mask manufacturing department, the mask blank manufacturing department provides optical characteristic information (transmittance variation) of the mask blank transparent substrate and optical characteristic information (transmittance variation and/or phase difference variation) of the mask blank to the mask manufacturing department. The optical characteristic information of the mask blank transparent substrate is provided to the mask blank manufacturing department from a materials processing department that manufactures mask blank transparent substrates. | 2010-07-08 |
20100173233 | PHOTOMASK BLANK, PHOTOMASK, AND METHODS OF MANUFACTURING THE SAME - A photomask blank has a light-shielding film composed of at least two layers on a transparent substrate. The light-shielding film includes a light-shielding layer made of a material mainly containing tantalum nitride and further containing xenon and a front-surface antireflection layer formed on the light-shielding layer and made of a material mainly containing tantalum oxide and further containing argon. | 2010-07-08 |
20100173234 | PHOTOMASK PRODUCING METHOD AND PHOTOMASK BLANK - In a photomask blank serving as a base member for producing a halftone-type phase shift mask in which a light-transmissive substrate is formed thereon with a light-semitransmissive phase shift pattern having a desired opening, a light-semitransmissive phase shift film, a chromium film, and an etching mask film are stacked in order on the light-transmissive substrate. The etching mask film is made of an inorganic-based material having a resistance against dry etching of the chromium film. The photomask blank further may has a resist film formed on the etching mask film. | 2010-07-08 |
20100173235 | METHOD AND APPARATUS FOR WRITING - A writing method includes calculating a proximity effect-corrected dose for correcting a proximity effect in charged particle beam writing, for each first mesh region made by virtually dividing a writing region of a target object into a plurality of first mesh regions of a first mesh size, calculating a fogging effect-corrected dose by using the proximity effect-corrected dose calculated and an area density in the first mesh size with respect to a part of a calculation region for calculating the fogging effect-corrected dose for correcting a fogging effect in the charged particle beam writing, and by using an area density in a second mesh size larger than the first mesh size with respect to a remaining part of the calculation region, synthesizing the fogging effect-corrected dose and the proximity effect-corrected dose for the each first mesh region, and writing a pattern on the target object by using a charged particle beam based on a synthesized correction dose. | 2010-07-08 |
20100173236 | EXPOSURE APPARATUS, AND METHOD OF MANUFACTURING DEVICE USING SAME - The exposure apparatus of the present invention is an exposure apparatus that illuminates an original with light from a light source so as to project a pattern of the original onto a substrate via a projection optical system for exposure, the exposure apparatus comprising a first shutter that shields light passing through a clearance between the light source and the projection optical system, and a control device that controls the opening and closing of the first shutter. While replacing a first original with a second original after an exposure operation has been completed by using the first original, the control device controls the first shutter such that the temperature of the projection optical system approaches closer to the projection optical system's saturation temperature that has been previously obtained via the second original. | 2010-07-08 |
20100173237 | Plate-making apparatus and printing plate manufacturing method - The plate-making apparatus according to an aspect of the present invention includes an exposure head which engraves a surface of a plate material by emitting a light beam toward the plate material; a scanning device which performs exposure scanning by relatively moving the plate material and the exposure head; a correction profile generation device which generates a correction profile for correcting an emission amount of the light beam emitted by the exposure head according to a characteristic difference of the plate material; and an exposure control device which, when a correction profile for a plate material to be used is generated by the correction profile generation device, uses the correction profile for the plate material to be used to control the emission amount of the light beam. | 2010-07-08 |
20100173238 | GAS CONTAMINATION SENSOR, LITHOGRAPHIC APPARATUS, METHOD OF DETERMINING A LEVEL OF CONTAMINANT GAS AND DEVICE MANUFACTURING METHOD - A gas contamination sensor includes an ion source configured to generate a beam of ions from a sample of gas to be tested, and first and second ion detectors, each positioned to receive ions from the beam of ions that are deflected by different extents. The first ion detector is configured to receive ions generated from a primary gas in the gas being tested, and the second ion detector is configured to receive ions that are generated from the contaminant gas within the sample being tested. | 2010-07-08 |
20100173239 | LOW MELT COLOR TONERS WITH FLUORESCENCE AGENTS - A low melt or ultra low melt toner includes at least one amorphous polyester of an alkoxylated bisphenol based polyester, a crystalline polyester derived from the reaction of an aliphatic dicarboxylic acid or aromatic dicarboxylic acid with an aliphatic diol, at least one colorant and at least one fluorescence agent. Methods of authentication of the toner, of authentication of documents formed from the toner, of embedding information in documents, and the like are also set forth. | 2010-07-08 |
20100173240 | POSITIVELY CHARGED DEVELOPER FOR DEVELOPMENT OF ELECTROSTATIC IMAGE AND PRODUCTION PROCESS THEREOF - A positively charged developer for development of electrostatic images, comprising positively charged toner particles and an external additive, wherein the positively charged toner particles are colored resin particles composed of aggregated and fusion-bonded particles of fine binder resin particles and fine colorant particles and having a shape factor SF-1 of 115 to 150 and a shape factor SF-2 of 110 to 140, and the external additive is an external additive containing positively charged inorganic particles subjected to a hydrophobization treatment with an amino group-containing compound, and a production process thereof. | 2010-07-08 |
20100173241 | POSITIVELY-CHARGEABLE TONER FOR DEVELOPING ELECTROSTATIC IMAGE - The present invention is to provide a positively-chargeable toner for developing electrostatic images which is applicable to a toner replenishment-type image forming device, is excellent in charge stability of toners and initial charging speed and thus producing less initial fog and being less likely to cause filming on photosensitive members upon replenishment of toners, can impart a stable charging ability to toner particles over time, and thus hardly causes deterioration of image quality due to fog or the like, and therefore is excellent in printing durability even if continuous printing of a large number of prints is performed. A positively-chargeable toner for developing electrostatic images comprising colored resin particles containing a binder resin, a colorant and a charge control agent, and an external additive, wherein the external additive contains fatty acid alkali metal salt particles or fatty acid alkaline earth metal salt particles having a number average primary particle diameter of 0.1 to 1 μm, and a content of the fatty acid alkali metal salt particles or the fatty acid alkaline earth metal salt particles is in the range from 0.01 to 0.5 parts by weight with respect to 100 parts by weight of the colored resin particles. | 2010-07-08 |
20100173242 | ELECTROPHOTOGRAPHIC TONER AND METHOD OF PREPARING THE SAME - An electrophotographic toner which includes a latex, a colorant, and a releasing agent, wherein characteristics of the electrophotographic toner measured by using a Fourier transform infrared spectroscopy in an attenuated total reflection mode (FT-IR-ATR), in which an incidence angle is changeable, satisfy Inequalities 1 through 3 presented herein. | 2010-07-08 |
20100173243 | APPARATUS AND METHOD FOR MANUFACTURING TONER - An apparatus for manufacturing toner is provided which includes a pulverizer for pulverizing a material into particles, a classifier for classifying the particles by size, a discharging path for discharging the particles from the pulverizer to the classifier, a returning path for returning relatively coarse particles among the classified particles from the classifier to the pulverizer, and a handling unit for handling particles. A method for manufacturing toner is also provided which includes pulverizing a material into particles in a pulverizer, discharging the particles from the pulverizer to a classifier via a discharging path, classifying the particles by size in the classifier, and returning relatively coarse particles among the classified particles from the classifier to the pulverizer. The handling unit is provided on at least one of the discharging path and the returning path, and includes a mechanism for preventing accumulation of the particles using airflow. | 2010-07-08 |
20100173244 | Toner Comprising Polyester, Process for Making the Toner and Uses Thereof - A process for preparing a toner comprising a binder resin and a colorant, wherein the binder resin comprises a polyester resin having an acid value greater than 5 mg KOH/g, the process comprising: providing an aqueous dispersion of polyester resin particles stabilised by an ionic surfactant and then associating the polyester resin particles. | 2010-07-08 |
20100173245 | Compositions comprising carboxy component and processes for photolithography - New photoresist compositions are provided that are useful for immersion lithography. Preferred photoresist compositions of the invention comprise one or more block copolymers. Particularly preferred photoresists of the invention can exhibit reduced leaching of resist materials into an immersion fluid contacting the resist layer dining immersion lithography processing. | 2010-07-08 |
20100173246 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION AND METHOD FOR FORMING CURED FILM USING THE SAME - The present invention provides a positive photosensitive resin composition including: a resin containing a specific acrylic acid-based constituent unit capable of undergoing dissociation of an acid-dissociable group to produce a carboxyl group, and a constituent unit having a functional group capable of reacting with the carboxyl group to form a covalent bond, the resin being alkali-insoluble or sparingly alkali-soluble and becoming alkali-soluble when the acid-dissociable group dissociates; and a compound capable of generating an acid upon irradiation with an actinic ray or radiation. The present invention also provides a method for forming a cured film using the composition. The positive photosensitive composition is excellent in the sensitivity, film residual ratio and storage stability and by the method for forming a cured film using the positive photosensitive resin composition, a cured film excellent in the heat resistance, adhesion, transmittance and the like can be provided. | 2010-07-08 |
20100173247 | SUBSTRATE PLANARIZATION WITH IMPRINT MATERIALS AND PROCESSES - The present invention relates to planarization materials and methods of using the same for substrate planarization in photolithography. A planarization layer of a planarization composition is formed on a substrate. The planarization composition contains at least one aromatic monomer and at least one non-aromatic monomer. A substantially flat surface is brought into contact with the planarization layer. The planarization layer is cured by exposing to a first radiation or by baking The substantially flat surface is then removed. A photoresist layer is formed on the planarization layer. The photoresist layer is exposed to a second radiation followed by development to form a relief image in the photoresist layer. The relief image is then transferred into the substrate. | 2010-07-08 |
20100173248 | PLATE SURFACE TREATMENT AGENT FOR LITHOGRAPHIC PRINTING PLATE AND METHOD FOR TREATING LITHOGRAPHIC PRINTING PLATE - A plate surface treatment agent for a lithographic printing plate is provided that includes a vinyl copolymer containing a monomer unit having at least one group selected from the group consisting of a phosphonic acid group, a phosphoric acid group, a carboxylic acid group, and a salt of these groups and a monomer unit having at least one group or structure selected from the group consisting of a sulfonic acid group, a salt thereof, an amide group, and a betaine structure. There is also provided a method for treating a lithographic printing plate that includes a step of imagewise exposing a lithographic printing plate precursor, a step of processing using a developer, and a step of carrying out a plate surface treatment using the plate surface treatment agent for a lithographic printing plate. | 2010-07-08 |
20100173249 | Method for Manufacturing a Semiconductor Device - Disclosed herein is a composition for removing an immersion lithography solution. The composition includes an organic solvent and an acid compound. Also disclosed is a method for manufacturing a semiconductor device including an immersion lithography process. When a photoresist pattern is formed by the immersion lithography process, an exposure process is performed on a photoresist film formed over an underlying layer with an immersion lithography exposer. Then, the composition is dripped over the wafer to remove residual immersion lithography solution on the photoresist film, thereby improving a water mark defect phenomenon. | 2010-07-08 |
20100173250 | METHOD FOR A MULTIPLE EXPOSURE, MICROLITHOGRAPHY PROJECTION EXPOSURE INSTALLATION AND A PROJECTION SYSTEM - In a method for multiply exposing at least one substrate coated with a photosensitive layer, a first exposure is carried out in accordance with a first set of exposure parameters on a first projection system ( | 2010-07-08 |
20100173251 | PHOTORESIST RESIDUE REMOVAL COMPOSITION - A photoresist residue removal composition is provided. The photoresist residue removal composition essentially contains glycolic and water, to which a pH control agent and/or a cleanability improver is selectively added. The photoresist residue removal composition has a high capability to remove residues caused by plasma etching and ashing of a metal or silicon oxide layer under a photoresist pattern, does not cause corrosion, and is eco-friendly | 2010-07-08 |
20100173252 | APPLIANCE CONTROL WITH AUTOMATIC DAMPER DETECTION - Methods and systems for operating a fuel fired appliance that may include an optional hardware component such as a damper are disclosed. In some cases, the presence of the optional hardware component is detected, and it is determined whether the optional hardware component is required for future operation of the fuel fired appliance. The fuel fired appliance may be operated normally if the optional hardware component is present and required, or, in some cases, if the optional hardware component is determined to be not required. If the optional hardware component is absent but required, normal operation of the fuel fired appliance may be stopped. | 2010-07-08 |
20100173253 | METHOD FOR OPERATING A COMBUSTION DEVICE, AND COMBUSTION DEVICE FOR CARRYING OUT THE METHOD - A combustion device ( | 2010-07-08 |
20100173254 | METHOD FOR EXTINGUISHING A CANDLE AT TIMED INTERVALS USING A COMBUSTIBLE MATERIAL - A method for extinguishing a candle at timed intervals using a combustible material is disclosed. In one exemplary embodiment, the method includes: utilizing a combustible composition adapted for application to a wick segment; utilizing a combustible first wick segment; coupling a combustible second wick segment to the combustible first wick segment; placing the combustible second wick segment adjacent to the first wick segment; and configuring the combustible second wick segment to, as the combustible first wick segment, once ignited, burns down to the combustible second wick segment, interrupt and slowly self-extinguish the burning of the first wick segment. The candle wick is configured to be relit, post extinguishment, without having to physically remove a non-combustible barrier. A combustible composition also is disclosed. A candle further is disclosed. | 2010-07-08 |
20100173255 | NOx-REDUCTION APPARATUS, METHOD OF MAKING, FURNACE, HVAC UNIT, AND BUILDING - NOx reduction apparatuses for use in heat exchangers or furnaces, HVAC units and buildings having such devices, and methods of making such devices. Wire embodiments may have a body, helix, or modified helix, and support members that extend outside the body to hold the body away from the heat exchanger or tube. The support members may be made of the wire, and may include bights, twisted bights, or larger (e.g., helical) turns, for instance, between groups of smaller helical turns. In some embodiments, a modified helix is formed by alternating bends and straight sections of wire. Some embodiments include an attachment mechanism that may be made from the wire and may include a hook. Wire may be Nichrome. Particular embodiments may allow burning of natural gas or LP without changing or removing the wire. | 2010-07-08 |
20100173256 | Surface Treated Polycrystalline Ceramic Orthodontic Bracket and Method of Making Same - An orthodontic bracket for coupling an archwire with a tooth. The orthodontic bracket comprising a ceramic injection molded (CIM) bracket body including an archwire slot that is configured to receive the archwire therein. The CIM bracket body comprising a polycrystalline ceramic. A coating of alumina or silicon dioxide is in continuous and direct contact with at least the surfaces of the archwire slot. The orthodontic bracket is characterized by unexpectedly high torque strength. The ceramic injection molded (CIM) bracket body may comprise a polycrystalline ceramic having a grain size distribution characterized by an average grain size in the range of larger than 3.4 μm to about 6 μm such that the orthodontic bracket is also characterized by unexpectedly high fracture toughness. A method of making the orthodontic bracket comprises injection molding a bracket using a ceramic powder, sintering the molded bracket, and coating the ceramic injection molded bracket. | 2010-07-08 |
20100173257 | SHADE GUIDE, METHOD FOR DISCRIMINATING TOOTH COLORS, ARTIFICIAL TOOTH MANUFACTURING METHOD - In a shade guide, a plurality of shade tabs whose colors are mutually different are arranged regularly based on the colors. The arrangement of the plurality of shade tabs is an arrangement determined based on: S values and V values that are determined according to to which areas, from among areas partitioned by a plurality of straight lines in an L*-C* plane, the coordinates of the colors of the shade tabs belong, and H values that are determined according to to which areas, from among areas partitioned by a plurality of straight lines in an a*-b* plane, the coordinates belong. S groups, each of which is a shade tab group having a common S value, are arranged in the shade guide. V rows, each of which is a shade tab group having a common V value, are arranged in each S group. In each V row, the plurality of shade tabs have mutually different H values and are aligned in an order that is in accordance with the H values. Using this shade guide enables precisely and easily discriminating the color of an evaluation target tooth. | 2010-07-08 |
20100173258 | Dental Articulator - A dental articulator is provided in which at least one of the two arms thereof has a base member that is articulated with respect to a bracket element onto which a dental model may be mounted, allowing independent movement of the dental model with respect to the pivot axis hingedly linking the arms. | 2010-07-08 |
20100173259 | DENTAL DRILL GUIDE SYSTEM - A dental drill guide system, including a handpiece guide which interfaces with a custom surgical guide. The custom surgical guide may be designed based on patient-specific data, such as medical images, for example, and fits conformingly over at least a portion of the patient's dentition at the implant site. The handpiece guide is attachable to an existing dental handpiece, and includes a guide protrusion that interfaces with a guide receptacle of the surgical guide to position and guide the movement of the drill along a desired trajectory. The guide receptacle may have a curved shape to allow for varying the position of the handpiece to aid surgeon access in the drilling procedure. | 2010-07-08 |
20100173260 | Artificial Tooth Root Implantation Position Determining Instrument, Artificial Tooth Root Implantation Position Determining Method, Guide Member Manufacturing Device, Sensor, Drill, Artificial Tooth Manufacturing Device, Computer Program, and Recording Medium - Dentition three-dimensional data and jaw-bone three-dimensional data are collected from a patient and they are combined. According to the combined data, dental crown data for making up for data on a lost tooth and occlusion data on a dental crown represented by the dental crown data are created. When an occlusion force according to the occlusion data is exerted on the occlusion face of a dental crown, a mechanical evaluation factor is produced in a jaw bone. The mechanical evaluation factor produced near the place where an artificial tooth root supporting a dental crown is to be implanted is calculated. The implantation place is determined so that the mechanical evaluation factor may be smaller and the mechanical load on the jaw bone from the opposed tooth during mastication may be lighter. | 2010-07-08 |
20100173261 | RECEIVING ELEMENT FOR AN IMPLANT - A receiving element for a dental implant, comprising a first plate and a second plate, extending perpendicular to the center axis of the receiving element and designed to detachably fix a dental implant in a stable position, wherein the plates are separated by an open portion. | 2010-07-08 |
20100173262 | Mixing tip for dental materials | 2010-07-08 |
20100173263 | ROTARY DRIVE CUTTER FOR DENTISTRY - A dental rotary drive cutting tool, which can limit breaking location to the shank side, and increase life span until breakage, is provided. A peeso reamer ( | 2010-07-08 |
20100173264 | NANOSURFACE - The invention relates to a method for modification of a biocompatible component comprising the steps of a) providing a biocompatible component at least partly covered by metallic oxide; and b) treating at least a part of said component, which part is covered by said metallic oxide, with an aqueous composition comprising oxalic acid; whereby a modified metallic oxide is obtained. The invention also relates to a biocompatible component comprising a substrate having a surface comprising a) a microstructure comprising pits separated by plateus and/or ridges; and b) a primary nanostructure being superimposed on said microstructure, said primary nanostructure comprising depressions arranged in a wave-like formation. | 2010-07-08 |
20100173265 | METHOD FOR CREATING THREE-DIMENSIONAL DATA OF POSITION OF OUTER PERIPHERY AT OCCLUSAL SURFACE SIDE OF KEEPER WITH RESPECT TO ABUTMENT FOR IMPLANT - A method for creating three-dimensional data of a position of an outer periphery at the occlusal surface side of a keeper includes steps of placing a keeper analog | 2010-07-08 |
20100173266 | SYSTEM AND METHOD FOR AUTOMATED GENERATING OF A CUTTING CURVE ON A SURFACE - In accordance with various aspects of the present invention, a system and method for automated generating of a cutting curve on a surface is provided. In accordance with an exemplary embodiment, a computer-implemented method for automated generating of a cutting curve on a gingival surface to facilitate cutting of an aligner material comprises the defining of initial gingival curves along the line around a tooth (LAT) on a patient's jaw, including within an interproximal area between teeth. The initial gingival curves are replaced with a modified, dynamic cutting curve comprising an offset adjustment configured to minimize weakening of a region of the aligner material within the interproximal area. This process for generating a modified, dynamic cutting curve within an interproximal area can be suitably applied or continued for each of other the teeth and interproximal areas between those teeth to define a complete dynamic cutting curve. The resulting complete dynamic cutting curve can then be output for conversion into machine executable code to facilitate cutting of the aligner material. | 2010-07-08 |
20100173267 | Method for producing restorative tooth preparation and treatment compositions and product - An improved product and method for production of a restorative tooth preparation and treatment composition that combines select organic acids and glutaraldehydes as a means to disinfect, desensitize, and etch in a single step that requires no rinsing. | 2010-07-08 |
20100173268 | PORTABLE TRACING DEVICE - Disclosed is a portable tracing device. The portable tracing device assists in tracing a picture from a picture paper sheet onto a plain paper sheet. The portable tracing device comprises a housing and at least one light source. The housing includes a plurality of panels configured together to define an interior volume thereof. Further, at least one panel of the plurality of panels is cut to configure at least one window to secure at least one light transmissible panel thereon for providing a support to the picture paper sheet and the plain paper sheet. Furthermore, the at least one light source is disposed within the interior volume of the housing. The at least one light source emits a path of light through the at least one light transmissible panel such that the picture of the picture paper sheet is visible onto the plain paper sheet placed thereabove. | 2010-07-08 |
20100173269 | FOOD RECOGNITION USING VISUAL ANALYSIS AND SPEECH RECOGNITION - A method and system for analyzing at least one food item on a food plate is disclosed. A plurality of images of the food plate is received by an image capturing device. A description of the at least one food item on the food plate is received by a recognition device. The description is at least one of a voice description and a text description. At least one processor extracts a list of food items from the description; classifies and segments the at least one food item from the list using color and texture features derived from the plurality of images; and estimates the volume of the classified and segmented at least one food item. The processor is also configured to estimate the caloric content of the at least one food item. | 2010-07-08 |
20100173270 | MATHEMATICS GAME - A mathematics game for playing by a plurality of players, includes a plurality of different types of dice. The dice include a first set of dice having a first predetermined number of faces with predetermined numeric values provided thereon; a second set of dice having the first predetermined number of faces with either “+” or “−” symbols provided on each of the faces (representing positive or negative); and a third set of dice having the first predetermined number of faces with different mathematical function symbols provided on the respective faces. The game also includes a score card provided for each of the plurality of players. The score card includes a first region for entering number values corresponding to a throw of the first type of dice; a second region for entering “+”/“−” values corresponding to a throw of the second type of dice; a third region for entering mathematical functions corresponding to a throw of the third type of dice; a fourth region for entering a mathematical equation based on information in the first, second and third regions; and a fifth region for entering a cumulative score of the respective player. | 2010-07-08 |
20100173271 | Computer operated by thought and emotions - My innovated computer doesn't need input devices like keyboards, mouse, light pen, etc; rather, it needs head cap in the form of comfortable headset to sense and to detect the instantaneous electrical signals generated in the brain according to the thought and emotions of the computer user as an input. The usage field of computer is as PC, Computer uses in: Investigation Purposes, Psychology, Neuro-psychiatry, Neurology. After the production of the computer Computing, information, communication and investigation fields will be revolutionized. | 2010-07-08 |
20100173272 | Method of verifying the existence of at least one unknown component in the body of a living being - Many people believe that your soul continues existing after your body is dead. The present invention is the method of verifying the existence of at least one unknown component in the body of a person or in the body of a living being. | 2010-07-08 |
20100173273 | METHOD AND DEVICE FOR TRAINING AND ASSISTING ALPINE SKIERS - A method and device are provided that allow a competent skier to train and/or assist a trainee downhill skier with the acquisition of basic downhill skiing techniques. The trainee skier is tethered to an uphill instructing skier by a pair of reins attached to the trainee at the ankles, ski tips, or to the ski tips via ski tip handles. The instructing skier has substantially independent control over each tethering point to assist or train the novice skier to execute turns, control speed, and promote proper balance and stance for the maneuver and terrain at hand. The method and device may also comprise the use of adjustable ski tip couplers that limit divergence, and optionally convergence, of the trainee's ski tips. Handicapped skiers may be assisted and guided in downhill skiing using this method and device. | 2010-07-08 |
20100173274 | METHODS AND SYSTEMS FOR TEACHING MOVEMENTS - Methods and systems for teaching movements are provided. One example method for teaching a desired movement to a subject includes presenting an idealized movement stimulus on a display during a presentation period. The method further includes reducing auditory sensory input and visual sensory input to the subject during an absorption period following the presentation period and during a practice period following the absorption period. The method further includes providing movement instruction to the subject to mimic a quality of the idealized movement stimulus with at least a portion of a subject's body during the practice period. The method further includes repeating the presenting and the reducing. | 2010-07-08 |
20100173275 | IMAGE GENERATION SYSTEM FOR DISPLAYING PRIMARY DISPLAY DATA AND SECONDARY DISPLAY DATA - Provided is an image generation system including a secondary data device having secondary display data stored thereon, and a console having a primary input communicable with a primary data source to receive primary display data therefrom. The console includes a secondary input communicable with the secondary data device to receive the secondary display data therefrom. A signal generator is in communication with the primary and secondary inputs for receiving the primary and secondary display data. The signal generator is configured to generate a display signal in a first mode for displaying images relating the primary display data and not the secondary display data, and a second mode for displaying images relating the primary display data and the secondary display data. The signal generator is configured to independently switch between generating the display signal in the first mode and the second mode. | 2010-07-08 |
20100173276 | TRAINING METHOD AND A DEVICE FOR CARRYING OUT SAID METHOD - The invention relates to training and can be used for learning and/or developing movement skills, fixing dynamic stereotypes and for training movement coordination. The aim of the invention is to provide a trainee with on-line correcting tactile feedback during training and to improve techniques and rate of a movement by bringing it as close as possible to a reference movement. The inventive training method consists, when learning a movement, in digitizing said movement, in comparing it with the digitized pattern of a reference movement and, if the trainee deviates from the reference movement, in receiving by said trainee a tactile feedback (tactile action) for on-line correcting said movement. The inventive device comprises sensors for on-line movement digitizing, a computer for comparing the thus obtained digitized movement with the reference movement (specified by an expert or simulated on the computer) for controlling the tactile feedback elements and said tactile feedback elements for performing the correction action. | 2010-07-08 |
20100173277 | Agent for Suppressing Rejection in Organ Transplantation Comprising Anti-HMGB-1 Antibody - An objective of the present invention is to provide effective methods for suppressing rejection in organ transplantation, in particular, pancreatic islet transplantation which is useful in treating diabetes. The present invention demonstrated that antibodies against HMGB-1 suppressed the rejection in pancreatic islet transplantation and promoted the survival of grafted pancreatic islets. Thus, the present invention provides agents that comprise an anti-HMGB-1 antibody for suppressing rejection in organ transplantation. | 2010-07-08 |
20100173279 | DETECTION USING PRIMERS TO REPETITIVE DNA AND TRANSCRIPTION-BASED AMPLIFICATION THEREBY - The present invention concerns identifying organisms based on detecting distinguishing patterns produced following RNA amplification that originates via a DNA template. In particular, the methods and compositions of the invention concern obtaining ds DNA from the organism in question, amplifying at least part of the DNA via RNA molecules from transcription using primers that target repetitive DNA, and detecting a hallmark pattern of the amplified RNA. | 2010-07-08 |
20100173280 | Systems for Detection and Production of Respiratory, Herpes and Enteric Viruses - The present invention generally relates to the field of diagnostic microbiology, and, more particularly, to compositions and methods for detecting and differentiating one or more viruses or other intracellular parasites present in a specimen. The present invention also provides compositions and methods to evaluate the susceptibility of organisms to antimicrobial agents. | 2010-07-08 |
20100173281 | HCV NS3 protease replicon shuttle vectors - The present invention provides for novel HCV NS3 protease replicon shuttle vectors useful for cloning in HCV polynucleotide sequences from samples of HCV-infected patients and testing the resulting replicons for drug susceptibility. | 2010-07-08 |
20100173282 | MUTATIONAL PROFILE IN HIV-1 GAG CLEAVAGE SITE CORRELATED WITH PHENOTYPIC DRUG RESISTANCE - The invention concerns novel mutations or mutational profiles of HIV-1 protease cleavage sites (CS) in the Gag region correlated with a phenotype causing alterations in sensitivity to anti-HIV drugs. The present invention also relates to the use of genotypic characterization of a target population of HIV and the subsequent association, i.e. correlation, of this information to phenotypic interpretation in order to correlate virus mutational profiles with drug resistance. The invention further relates to methods of utilizing the mutational profiles of the invention in databases, drug development, i.e., drug design, and drug modification, therapy and treatment design and clinical management. | 2010-07-08 |
20100173283 | METHOD OF PREDICTING POTENTIAL SEVERITY OF HEPATITIS E, PROBE SETS, AND PRIMER SETS - The present invention provides a method of predicting potential severity of hepatitis, includes determining that hepatitis in a subject is potentially severe when it is detected that any amino acid is mutated to an amino acid of genotype-4, the any amino acid being amino acid of an amino acid sequence in a region encoded by ORF1 of an HEV genome RNA of genotype 3, and the HEV genome RNA being contained in a specimen nucleic acid taken from the subject infected with genotype-3 HEV. | 2010-07-08 |
20100173284 | Method for Detection of HCV at the Real Time PCR with Intercalating Dye - The present invention relates to a composition for detection of HCV by a single step reaction, comprising a specific primer and probe. In particular, the present invention relates to a composition for detection of HCV by a single step reaction, comprising the primer sequences of SEQ ID NOs:1 and 2; a composition for detection of HCV by a single step reaction, comprising both the primer sequences and a probe of SEQ ID NOs:5 or 9; a method for detecting HCV by a single step reaction, comprising the steps of obtaining a sample from a subject, and amplifying and detecting HCV using the primer and probe; and a kit comprising the primer and probe, in which the HCV detection method is characterized by a single step reaction. | 2010-07-08 |
20100173285 | Methods and Compositions for Detecting a Drug Resistant Egfr Mutant - Polymerase chain reaction primers and methods directed to detecting the EGFR mutant C→T at the position corresponding to base 2369 of EGFR cDNA. The invention provides a PCR primer that hybridizes under suitable PCR conditions to a polynucleotide sequence 5′ in each respective strand to a mutation of an EGFR gene that encodes a substitution of threonine by methionine at position 790 of the EGFR polypeptide. The invention also provides a PCR primer hybridizes to a sequence that includes a mutant T at the position corresponding to base 2369 of EGFR cDNA but not to a second EGFR polynucleotide containing a wild type C. The invention provides several methods and kits for detecting a mutant epidermal growth factor receptor (EGFR) gene in a sample comprising probing the sample with a means for selectively detecting a nucleotide sequence comprising a mutant T at the position corresponding to base 2369 of EGFR cDNA, and identifying that the base at said position is T. These methods and kits are also useful to predict resistance to the therapeutic effects of gefitinib or erlotinib in a subject suffering from or suspected of having a cancer. | 2010-07-08 |
20100173286 | Mutant Cells Suitable for Recombinant Polypeptide Production - A mutated bacterial cell producing at least one heterologous polypeptide of interest, wherein said cell has a reduced expression-level of YugJ (SEQ ID NO: 2) or a homologue thereof when compared with an otherwise isogenic but non-mutated cell; methods for producing said cell, and methods for producing a polypeptide of interest using said cell. | 2010-07-08 |
20100173287 | METHOD OF ANALYZING NUCLEIC ACID - According to the present invention, stable amplification of a small amount of nucleic acid and analysis of the same with good sensitivity can be realized by improving efficiency of hybridization primers or probes with a probe. Specifically, the present invention relates to a method of analyzing nucleic acid comprising: a step of hybridizing at least one type of a first probe comprising a 1 | 2010-07-08 |
20100173288 | SERUM/PLASMA MICRONAS AND USES THEREOF - This invention provides a combination of microRNAs for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable microRNAs stably existing in the serum/plasma of a subject; and a method for evaluating the physiological and/or pathological condition of a subject, wherein the method includes determining all detectable microRNAs stably existing in the serum/plasma of a subject; and a kit for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable microRNAs that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable microRNAs stably existing in the serum/plasma of a subject. The aforementioned combination, method, kit and biochip can be used for diagnosis as well as differentially diagnosis of diseases including various tumors; various acute/chronic infectious diseases, e.g. viral diseases such as viral influenza, viral hepatitis, AIDS, SARS, bacterial diseases such as tuberculosis, bacterial pneumonia, and other acute/chronic infectious diseases caused by various pathogenic microorganisms; other acute/chronic diseases such as diseases of respiratory system, diseases of immune system, diseases of blood and hematopoietic system, diseases of circulatory system such as cardio-cerebrovascular diseases, metabolic diseases of endocrine system, diseases of digestive system, diseases of nervous system, diseases of urinary system, diseases of reproductive system and diseases of locomotor system, prediction of complications occurrence and malignant diseases relapse, evaluation of therapeutic effects, screening of pharmaceutical active ingredients, assessment of drug efficacy as well as forensic authentication and prohibited drug inspection and the like, possessing a number of advantages such as extensive detection spectrum, high sensitivity, low cost, convenience for sampling, ease for sample preservation, etc. The said method can be widely used in work related to general survey of diseases and so on, improve the low-specificity and low-sensitivity caused by individual differences which single markers are difficult to overcome, significantly increasing the clinical detection rate of diseases, all of which make it become an effective means for diagnosing diseases in an early phase. | 2010-07-08 |
20100173289 | Methods for Assessing Cancer Susceptibility to Carcinogens in Tobacco Products - The present invention demonstrates the differential sensitivity of PBLs from lung cancer patients and healthy controls to NNK-induced genetic damage. The data provide convincing evidence that the preferred CBMN assay is a robust test for detection of this sensitivity and yields results that are a good predictor of, for example, lung cancer risk. The simplicity, rapidity, and sensitivity of the CBMN test make it a valuable tool for screening and, for example, prioritizing potential cases for early detection of the disease. | 2010-07-08 |
20100173290 | MONITORING OF ENZYMATIC PROCESSES BY USING MAGNETIZABLE OR MAGNETIC OBJECTS AS LABELS - The present invention provides a method and device for monitoring an enzymatic process of a biological molecule by, at least once, during the enzymatic process determining an amount of magnetic particles attached to a sensor surface. The method and device according to embodiments of the present invention may be used for monitoring an enzymatic process as a function of time. | 2010-07-08 |
20100173291 | METHODS AND KITS FOR DETECTING FETAL CELLS IN THE MATERNAL BLOOD - Provided is a method of identifying a trophoblast by detecting in cells of a biological sample, with the proviso that the biological sample does not comprise a placental tissue, expression of a trophoblast marker selected from the group consisting of an annexin IV, a cytokeratin-7, a cytokeratin-8 and a cytokeratin-19; and classifying cells exhibiting expression of the trophoblast marker as trophoblasts. Also provided are methods of detecting a pregnancy in a subject, isolating trophoblasts from biological samples and prenatally diagnosing a conceptus using the identified trophoblasts. | 2010-07-08 |
20100173292 | NOVEL GPIIIa GENE - An object of the present invention is to provide a probe, primer, primer set and antibody for determining neonatal alloimmune thrombocytopenic purpura or the risk of developing it. According to the present invention, there is provided a probe, primer, primer set and antibody for use in the detection of the thymine residue at position 1297 in the GPIIIa. | 2010-07-08 |
20100173293 | High Density Sequence Detection Methods - A method for performing PCR on a liquid sample comprising a plurality of polynucleotide targets, wherein each polynucleotide target is present at very low concentration within the sample. The method comprises applying PCR reactants to the surface of a substrate to produce a plurality of reaction spots on the surface of the substrate; loading the liquid sample and a PCR reagent mixture onto the reaction spots; forming a sealed reaction chamber, having a volume of less than about 20 nanoliters, over each of the reaction spots; and amplifying the sample. | 2010-07-08 |
20100173294 | DIAGNOSTIC TEST FOR SUSCEPTIBILITY TO B-RAF KINASE INHIBITORS - The present invention provides methods and reagents for the detection of a mutation in BRAF and methods of selecting patients for treatment if a B-Raf kinase inhibitor, such as a selective B-Raf kinase inhibitor | 2010-07-08 |
20100173295 | FIXATION OF A BIOLOGICAL MATERIAL - The present invention relates to a method for the treatment of a biological material, comprising the steps i) providing a biological material, and ii) contacting the biological material with a first non-aqueous composition comprising: (a1) 10 to 90 vol. % methanol, and (a2) at least one additional additive, and (a3) optionally an acid. iii) transferring the biological material into a second composition (B) comprising up to 99 vol. % ethanol as well as to a new composition for preservation of a biological material usable in said method and the biological material resulting from this method, a method for the analysis of a treated biological material, various kits as well as the use of the composition in such a method. | 2010-07-08 |
20100173296 | METHODS OF STRATIFYING ADOLESCENT IDIOPATHIC SCOLIOSIS, ISOLATED NUCLEIC ACID MOLECULES FOR USE IN SAME AND KITS USING SAME - A method of stratifying a subject having adolescent idiopathic scoliosis (AIS) comprising: providing a cell sample isolated from the subject; detecting Paired-like homeodomain transcription factor 1 (Pitxi) expression in the cell sample; whereby the results of the detecting step enables the stratification of the subject having AIS as belonging to an AIS subclass. | 2010-07-08 |
20100173297 | NOVEL SERPENTINE TRANSMEMBRANE ANTIGENS EXPRESSED IN HUMAN CANCERS AND USES THEREOF - Described is a novel family of cell surface serpentine transmembrane antigens. Two of the proteins in this family are exclusively or predominantly expressed in the prostate, as well as in prostate cancer, and thus members of this family have been termed “STEAP” (Six Transmembrane Epithelial Antigens of the Prostate). Four particular human STEAPs are described and characterized herein. The prototype member of the STEAP family, STEAP-1, appears to be a type IIIa membrane protein expressed predominantly in prostate cells in normal human tissues. Structurally, STEAP-1 is a 339 amino acid protein characterized by a molecular topology of six transmembrane domains and intracellular N- and C-termini, suggesting that it folds in a “serpentine” manner into three extracellular and two intracellular loops. STEAP-1 protein expression is maintained at high levels across various stages of prostate cancer. Moreover, STEAP-1 is highly over-expressed in certain other human cancers. | 2010-07-08 |
20100173298 | HCV GENE - The present invention provides a hepatitis C virus gene, a replicon RNA derived from the gene, a replicon-replicating cell into which the replicon RNA is introduced, and a method for screening a drug using the replicon-replicating cell. By introducing a replicon RNA comprising (A) a polynucleotide having the nucleic acid sequence shown in SEQ ID NO: 5; (B) a polynucleotide having the nucleic acid sequence shown in SEQ ID NO: 7; (C) a polynucleotide coding for a polypeptide having the amino acid sequence shown in SEQ ID NO: 6; (D) a polynucleotide coding for a polypeptide having the amino acid sequence shown in SEQ ID NO: 8; or (E) a polynucleotide having a nucleic acid sequence having a homology of not less than 90% with the nucleic acid sequence shown in SEQ ID NO: 5 or SEQ ID NO: 7; or a replicon RNA of the genotype 1b comprising nucleotides coding for the 1804th amino acid leucine and the 1966th amino acid lysine in the amino acid sequence of a hepatitis C virus polyprotein and a polynucleotide coding for an NS4B protein, into a cell, the replicon-replicating cell can be prepared. By using the replicon-replicating cell, the screening for the drug can be carried out. | 2010-07-08 |
20100173299 | MUTANT NUCLEIC ACID RELATED TO CHRONIC MYELOPROLIFERATIVE DISORDER AND METHOD OF EVALUATING CHRONIC MYELOPROLIFERATIVE DISORDER - A new mutant gene related to the onset of CMPD, particularly, the new mutant gene related to the onset of CMPD in patients who develop CMPD despite of JAK2 | 2010-07-08 |
20100173300 | NONCONTACT STIRRING METHOD, NONCONTACT STIRRING APPARATUS, METHOD AND APPARATUS FOR REACTING NUCLEIC ACID HYBRIDIZATION USING THE APPARATUS, METHOD FOR DETECTING NUCLEIC ACID IN SAMPLE, APPARATUS FOR DETECTING NUCLEIC ACID, METHOD FOR DETECTING ANTIBODY IN SAMPLE, APPARATUS FOR DETECTING ANTIBODY - A noncontact stirring method, a noncontact stirring apparatus, a method and apparatus for reacting nucleic acid hybridization using the apparatus, a method for detecting nucleic acid in a sample, an apparatus for detecting nucleic acid, a method for detecting antibodies in a sample, and an apparatus for detecting antibodies in minute droplets 1 μmL or less in an electric field are proposed that can be utilized to speed up biodetection processes, hybridization processes in DNA analysis, ELISA antigen fixing processes, blocking processes, antibody-antigen reaction processes and color reaction processes; and pathogen identification, CRP tests, methods of propagating cells or bacilli such as colon bacilli in a liquid culture medium, and chemical analyses. | 2010-07-08 |
20100173301 | PROGNOSTIC TOOLS TO PREDICT THE EFFICACY OF DRUG TREATMENT TARGETING CHROMATIN DNA OR ENZYMES ACTING ON DNA - Disclosed are methods of predicting cell response to drug-based therapy using both PCR-Stop assays and real time PCR assays. Methods herein may be used for assessment of drug effect, evaluation of regimen suitability for a given patient, and/or for determination of an optimal drug dose. Also provided are isolated oligonucleotide primers such as primers capable of annealing under PCR conditions to a segment of a c-myc locus, where the primers may be used in the disclosed methods. Further disclosed are kits and systems that may be used for predicting a cell response to drug-based therapy. | 2010-07-08 |
20100173302 | POSITIVE CONTROL PROTEINS FOR GLUCOSE TRANSPORTER PROTEINS AND PROCESSES FOR THE GENERATION OF SUCH POSITIVE CONTROL PROTEINS - Positive controls for experimentation related to membrane-bound glucose transporter proteins and methods for preparing such positive controls, such proteins including GLUT1, GLUT4, GLUT5, and GLUT12. | 2010-07-08 |
20100173303 | MULTIBASE DELIVERY FOR LONG READS IN SEQUENCING BY SYNTHESIS PROTOCOLS - The present technology relates to molecular sciences, such as genomics. More particularly, the present technology relates to methods for obtaining long lengths of sequencing data. | 2010-07-08 |
20100173304 | METHOD OF DNA SEQUENCING - The invention includes a method for sequencing DNA by partially sequencing the bases of complementary strands of double-stranded DNA and combining the partial information from both strands of the double strand DNA to fully sequence the DNA. The invention also includes DNA sequences sequenced by the methods, computer readable mediums including program instructions for such methods, and kits adapted to perform such methods. | 2010-07-08 |
20100173305 | COMPOSITIONS, KITS AND RELATED METHODS FOR THE DETECTION AND/OR MONITORING OF LISTERIA - Provided are compositions, kits, and methods for the identification of | 2010-07-08 |
20100173306 | METHOD FOR DETECTING G-QUADRUPLEX, METHOD FOR DETECTING G-QUADRUPLEX-FORMING DNA AND METHOD FOR DETERMINING TELOMERASE ACTIVITY - The present invention provides a method for specifically detecting a G-quadruplex, and the like. | 2010-07-08 |
20100173307 | NUCLEIC ACID MODULES FOR EXPRESSION AND TAGGING OF MEMBRANE PROTEINS AND METHODS OF USE - Described herein are nucleic acid modules for cloning, expression and tagging of eukaryotic membrane proteins. The nucleic acid modules include a receptor for advanced glycation end products (RAGE) signal sequence, a nucleic acid sequence encoding a tag and a multiple cloning sequence (MCS). Any membrane protein of interest can be cloned into the MCS for expression in cells. The nucleic acid modules can encode any type of tag, such as an epitope tag or affinity tag. The nucleic acid modules disclosed herein can be used to express any type of membrane protein and are particularly suited to the expression and tagging of Type I and Type III membrane proteins. | 2010-07-08 |
20100173308 | Systems for genome selection - Systems, methods, compositions and apparatus relating to genome selection are disclosed. | 2010-07-08 |
20100173309 | SITU METHODS FOR GENE MAPPING AND HAPLOTYPING - The present invention is directed to in situ methods for providing a definitive haplotype of a subject. The haplotype information generated by the methods described herein is more accurate than that provided by prior art methods that only give an inferred haplotype. Accordingly, in one aspect the present invention provides an in situ method for obtaining genetic information for a polyploid subject, the method including the steps of obtaining a biological sample from the subject, the sample containing: (i) at least one paternally-derived DNA molecule, and/or (ii) at least one maternally-derived DNA molecule, analyzing any one or more of the paternally- or maternally-derived DNA molecules for nucleotide sequence information, wherein the step of analyzing determines whether any two DNA markers are present in cis on one chromosome, or in trans across two sister chromosomes. Use of in situ methods such as FISH allows for the provision of phase-specific information on DNA markers without recourse to methods for physically separating sister chromosomes. Applicants propose that method eliminates the problem of incorrect or misleading inferences concerning the phase of two or more loci within a haplotype, and allows for revelation of two or more participatory genes within a haplotype, uncomplicated by differences in modes of inheritance. | 2010-07-08 |
20100173310 | MICROCHIP LARGE-VOLUME PCR WITH INTEGRATED REAL-TIME CE DETECTION - A microfluidic device is provided with appropriate integrated structures to conduct large volume PCR and end-point or real-time capillary electrophoresis detection The microfluidic device includes a substrate having an amplification chamber of a volume of nucleic acid, wells disposed on the substrate, flow channels connecting the wells and the chamber in the substrate to allow for solution flow through the chamber, and one or more separation channels provided in the substrate and connected to the chamber for separating and detecting a fraction of the amplified nucleic acid The chamber, the flow channels, and the one or more separation channels are configured such that the hydrodynamic flow resistance of the chambers and the flow channels combined is at least 10Λ3 times smaller than the hydrodynamic flow resistance in the one or more separation channels The microfluidic device can achieve a very high sensitivity in detection while being highly cost effective | 2010-07-08 |
20100173311 | NUCLEIC ACID AMPLIFICATION WITH ALLELE-SPECIFIC SUPPRESSION OF SEQUENCE VARIANTS - The present invention is an improved method of selective amplification of certain variants of the target sequence, enhanced by allele-specific suppression of amplification of one or more of the other variants of the target sequence. The improvement is accomplished by providing an oligonucleotide, capable of hybridizing to the desired variant of the target sequence with the lesser affinity than to the undesired variants of the target sequence and optionally, by providing chemically modified primers and hot-start conditions. | 2010-07-08 |
20100173312 | GENETIC LESION ASSOCIATED WITH CANCER - The invention comprises methods for identifying mutations within the 3′ UTRs of genes that lead to increased risk or probability of developing cancer. | 2010-07-08 |
20100173313 | BIOMARKERS OF INFLAMMATION - Methods for the detection of DP | 2010-07-08 |
20100173314 | DIAGNOSTIC METHODS USING TENASCIN-W COMPOSITIONS - Tenascin-W. an extracellular matrix molecule that is specifically expressed in metastatic tumours is provided. A system comprising a sample expressing tenascin-W is used as an in vitro method for screening possible anti-tumour agents or for agents that promote osteogenesis. | 2010-07-08 |
20100173315 | Assay Particles and Methods of Use - The invention provides assay particles useful, for example, for detecting analytes and binding molecule interactions. One type of assay particle includes a core portion encased by a shell portion, wherein the shell portion comprises an inorganic phosphor that binds selectively to a target molecule. Another type of an assay particle includes a core portion encased by a shell portion, and a coat portion covering the shell portion, wherein the coat portion comprises an inorganic phosphor that binds selectively to a target molecule. A further type of assay particle includes a core portion encased by a shell portion, and a coat portion covering the shell portion, wherein the coat portion comprises an inorganic phosphor and a target selective binding moiety, and wherein the assay particle is buoyant in aqueous media. An additional type of assay particle includes a core portion encased by a shell portion, and a coat portion covering the shell portion, wherein the shell portion comprises an inorganic phosphor and the coat portion comprises a target selective binding moiety, and wherein the assay particle is buoyant in aqueous media. Also provided are kits and related methods. | 2010-07-08 |
20100173316 | PROBE, PROBE SET, PROBE CARRIER, AND TESTING METHOD - A probe, a set of probes, and a probe carrier on which the probe or the set of probes is immobilized, are provided for classification of fungus species. The probe or the set of probes is capable of collectively detecting fungus of the same species and distinguishingly detecting those fungus from fungus of other species. The probe is an oligonucleotide probe for detecting a pathogenic fungus DNA and includes at least one of base sequences of SEQ ID NOS. 1 to 2 and mutated sequences thereof. | 2010-07-08 |
20100173317 | METHOD FOR DIAGNOSING NON-SMALL CELL LUNG CANCER - Disclosed are methods for detecting non-small cell lung cancer (NSCLC) using differentially expressed genes KIF11, GHSR1b, NTSR1, and FOXM1. Also disclosed are methods of identifying compounds for treating and preventing NSCLC, based on the interaction between KOC1 and KIF11, or NMU and GHSR1b or NTSR1. | 2010-07-08 |
20100173318 | METHOD AND SYSTEM FOR MODELING CELLULAR METABOLISM - This invention relates to methods and systems for in silico or bioinformatic modeling of cellular metabolism. The invention includes methods and systems for modeling cellular metabolism of an organism, comprising constructing a flux balance analysis model, and applying constraints to the flux balance analysis model, the constraints selected from the set consisting of: qualitative kinetic information constraints, qualitative regulatory information constraints, and differential DNA microarray experimental data constraints. In addition, the present invention provides for computational procedures for solving metabolic problems. | 2010-07-08 |
20100173319 | COMPOSITIONS AND METHODS FOR CANCER DIAGNOSIS AND THERAPY - The miR15 and miR16 micro RNA genes are located at 13q14 within a 30 kb region of loss characteristic of cells from certain cancers, such as cells from chronic lymphocytic leukemia or prostate cancer. Chronic lymphocytic leukemia or prostate cancer can be diagnosed by detecting a reduction in miR15 or miR16 gene copy number, by determining miR15 or miR16 gene mutational status, or by detecting a reduction in the RNA transcribed from these genes. The miR15 or miR16 gene products can inhibit the neoplastic or tumorigenic growth of cancers such as chronic lymphocytic leukemia or prostate cancer cells when administered to subjects suffering from these diseases. | 2010-07-08 |
20100173320 | Methods for Detecting Nucleic Acids Indicative of Cancer - The invention provides methods for screening tissue or body fluid samples for nucleic acid indicia of cancer or precancer. | 2010-07-08 |
20100173321 | Making a diagnosis in cases of cardiac disease using a combination of markers - The present invention concerns methods for diagnosing myocardial infarction, for performing risk stratification of myocardial infarction, for making a prognosis of a disease course in a myocardial infarction patient, for identifying a patient with elevated risk of myocardial infarction, or combinations thereof, wherein a determination of at least three markers is performed on a patient sample. Furthermore, kits for performing the methods are provided. | 2010-07-08 |
20100173322 | Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways - The invention discloses nearly 219 novel phosphorylation sites identified in signal transduction proteins and pathways underlying Anaplastic Large Cell Lymphoma (ALCL) involving the NPM-ALK translocation/fusion, and provides phosphorylation-site specific antibodies and heavy-isotope labeled peptides (AQUA peptides) for the selective detection and quantification of these phosphorylated sites/proteins, as well as methods of using the reagents for such purpose. | 2010-07-08 |
20100173323 | GLYCOSYLATION ENGINEERED ANTIBODY THERAPY - The instant invention is drawn to methods of generating a glycosylation-engineered antibody, and using the glycosylation-engineered antibody for treating a patient, particularly a cancer patient or a patient with an immune disease or disorder. The instant invention is also drawn to methods of generating a glycosylation-engineered antibody for use in the treatment of patients having a polymorphism that does not respond to conventional antibody therapy. The instant invention is also drawn to methods of improving the biological activity of an antibody by glycosylation engineering. The instant invention is also drawn to methods of modulating antibody-dependent cell-mediated cytoxicity (ADCC) using a glycosylation-engineered antibody. | 2010-07-08 |
20100173324 | ANTI-CD27 ANTIBODY - The present invention provides a monoclonal antibody which specifically recognizes CD27 containing an O-linked sugar chain to which galactose is not bound and binds to its extracellular region, or a method for using the same. | 2010-07-08 |
20100173325 | Composition and Method for Analysis of Target Analytes - A method of detecting analytes includes providing a mixture containing analytes to be analyzed and microparticles coated with competitive inhibitors of the analytes. First antibodies are reacted with the analytes and the competitive inhibitors under competitive binding conditions. The first antibodies bound to the competitive inhibitors are measured using flow cytometry. | 2010-07-08 |
20100173326 | SUBSTRATE AND METHOD FOR PRODUCING THE SUBSTRATE - A self assembling monolayer formed by the self assembling molecules is caused to bond onto the surface of a base material, and chelators are caused to bond onto the self assembling monolayer, to produce a substrate, in which the chelators are bound to the self assembling monolayer at a density within a range from 0.4/nm | 2010-07-08 |
20100173327 | NONHUMAN MODEL ANIMAL LACKING THE ABILITY TO CONTROL LYMPHOCYTE MIGRATION - The present invention provides a animal model useful in identifying a molecule controlling in a lymphocyte-specific manner migration and thus elucidating immune-related diseases and pathogenic conditions such as allergy, autoimmune diseases, GvH and graft rejections at a molecular level, or in developing a novel therapy. A nonhuman animal model such as a DOCK2 knockout mouse, in which the function to control lymphocyte migration has been deleted or suppressed, is generated by deleting DOCK2 gene on the chromosome. In this DOCK2 knockout mouse, the function of activating Rac to mediate actin cyteskeleton, the lymphocyte migration function in response to stimuli with chemokines such as SLC, SDF-1, BLC, the homing function to secondary lymphoid organs such as spleen, lymph nodes and Peyer's patches, and the function of emigrating mature thymic T cells into peripheral blood in response to stimulus with chemokine ELC are impaired, and as a result of this, immune responses are suppressed. | 2010-07-08 |