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26th week of 2013 patent applcation highlights part 58
Patent application numberTitlePublished
20130165875TRANSDERMAL ABSORPTION PREPARATION - The present, invention relates to a transdermal absorption preparation. The transdermal absorption preparation of the present invention comprises a drug-containing adhesive layer, a drug-protective layer and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, rubber, an adhesion-imparting resin, an antioxidant, and a transdermal absorption promoter. Also, the present invention provides a transdermal absorption preparation comprising a drug-containing adhesive layer, a drug-protective layer, and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, acrylic rubber, an anti-crystallisation agent, and a transdermal absorption promoter. When the transdermal absorption preparation of the present invention is used for the treatment of Parkinson's disease or restless leg syndrome, no side effect due to an increase in the initial drug concentration in blood occurs and the skin penetration effect of the drug is excellent.2013-06-27
20130165876PATCH PREPARATION - The present invention relates to a patch preparation having a central part and a peripheral part surrounding the central part, the patch preparation comprising: a patch preparation main body having a support and an adhesive layer which contains a drug and is formed on the support; and a release liner laminated on the adhesive layer, wherein the peripheral part has a predetermined area, and a peel force between the adhesive layer and the release liner in the predetermined area is greater than a peel force between the adhesive layer and a release liner in the central part.2013-06-27
20130165877AUGMENTED CHEST TUBE DRAINAGE SYSTEM AND METHOD WITH VOLUME SENSING, AUTOMATED ALERTS AND MESSAGING CAPABILITY - Systems and methods that can augment conventional chest tube drainage canisters are discussed. One such system can monitor a chest tube drainage canister that collects fluid and includes a volume sensor that can determine a volume of the fluid. Such a system can also include a control component that calculates a flow rate of the fluid. The control component can compares the volume and the flow rate with one or more predetermined conditions, and the control component provides at least one notification to a healthcare professional when at least one of the predetermined conditions are met. Additionally, a user interface can be provided for monitoring fluid volume and flow rate, entering alerts capable of defining conditions for notification of healthcare professionals, and entering contact information for automatic notification of healthcare professionals via email or text message in connection with the alerts.2013-06-27
20130165878Wound Filler Material with Improved Nonadherency Properties - An apparatus for promoting the healing of an exuding wound includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained. The cover may form a substantially fluid-tight seal around the wound and permit fluid communication between the reservoir and a vacuum source suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound. A wound filler positioned between the wound and the wound cover includes a fibrous material treated with a surface modification additive.2013-06-27
20130165879Location of Fatty Acid Esters on Tampons and Toxin Inhibiting Efficacy - The application of active ingredients, exemplified by GML, to absorbent fibers, such as rayon fibers, used in tampon manufacture at very low levels has been found to maintain efficacy in the inhibition of the production of toxic shock syndrome toxin one (TSST-1) produced by 2013-06-27
20130165880ANTIMICROBIAL DISPOSABLE ABSORBENT ARTICLES - Disposable absorbent articles comprising an absorbent material and an antimicrobial composition are disclosed. The antimicrobial composition includes a carrier comprising fatty alcohol and a poly(alkyleneoxy) polymer, and an antimicrobial agent. The antimicrobial composition may be coated on to component substrates such as nonwovens and films, that are incorporated into disposable absorbent articles, such as disposable infant diapers, adult incontinence articles, feminine hygiene articles such as sanitary napkins, wound dressings, bandages, panty liners and tampons, personal care wipes and household wipes to provide odor control, and control of microbial growth.2013-06-27
20130165881LEAKAGE-REDUCING DRESSING - An adhesive dressing that reduces the leakage of wound exudate from the dressing, comprising an adhesive-coated backing sheet; and an absorbent island adhered to said adhesive-coated backing sheet by said adhesive, having a first end and a second end, wherein the absorption capacity of the absorbent island is higher at the first end than at the second end. The adhesive dressing of the invention provides extended wear time for the dressing when it is applied to wounds.2013-06-27
20130165882BODILY FLUID ABSORBENT ARTICLE - A bodily fluid absorbent article adapted to absorb bodily fluid over a wide range thereof. An absorbent structure in the bodily fluid absorbent article includes an upper absorbent component and a lower absorbent component. The absorbent structure further includes one of a dispersing surface constituting the upper absorbent component and kept in contact with the lower absorbent component and a dispersing surface constituting the lower absorbent component and kept in contact with the upper absorbent component. Such dispersing surface exhibits a dispersion velocity for bodily fluid higher than those exhibited by the absorbent sections defined immediately above and under this dispersing surface.2013-06-27
20130165883NONWOVEN FABRIC, METHOD FOR PRODUCING IT, AND ABSORBENT ARTICLE - A nonwoven fabric that minimizes the condition of rewet-back in which fluid absorbed into an absorbent body exudes out to the front side, as well as a method for producing it. The nonwoven fabric has a mutually perpendicular machine direction (MD), cross-machine direction (CD) and thickness direction, and has in the thickness direction a front side and a back side on the side opposite it, having on the front side heights and recesses formed so as to extend in an alternating fashion parallel to each other in the MD direction, forming repeating corrugations in the CD direction, and on the back side a back side section formed across the entire side, the heights being composed of height tips located at the tips of the heights and neck sections connecting the height tips with the back side section, the cross-sectional widths of the neck sections being narrower than the height tips in a cross-section of the heights in the CD direction, and having spaces between the recesses formed by the two neck sections supporting each of the adjacent height tips, and the back side section.2013-06-27
20130165884LINER FOR INCONTINENCE - A liner for incontinence includes a skin contact side sheet, a non-skin contact side sheet, and an absorbent body arranged between these sheets and including an absorbent material. The absorbent material includes 30 to 70 mass % of SAP. The liner includes a main body and wings in an intermediate region of the main body. An SAP basis weight in the intermediate region is larger than in front and rear regions of the main body. The main body includes a front compressed region which is positioned between the intermediate region and the front region immediately in front of a urinating position (UP) of a wearer when worn, side compressed regions which extend from the intermediate region to the front region and rear region, respectively, and a rear compressed region which extends in the rear region in substantially the width direction. At the compressed regions, the absorbent body is continuous.2013-06-27
20130165885ABSORBENT ARTICLE - An absorbent article, such as a sanitary napkin and the like, constituted of an absorbing body between permeable (skin contact surface) and impermeable (skin non-contact surface) sheets, is provided with intermittent recess grooves formed in a longitudinal direction on the absorbent article on the skin non-contact surface side of the absorbing body, a plurality of laterally elongated peripheral embosses formed at intervals in the longitudinal direction of the absorbent article on absorbent body areas located peripherally to the recess grooves, and an absorbing body deficit portion formed at least between the recess grooves. Thus achieved are close contact with buttock cleavage and prevention of leakage to the rear.2013-06-27
20130165886Absorbent Core and Disposable Absorbent Product with Such Absorbent Core - A disposable absorbent product extends along a longitudinal dimension and a width dimension. The absorbent product has a backsheet, a topsheet overlaying the backsheet, and an absorbent core disposed between the backsheet and the topsheet for absorbing and retaining fluid secreted by a wearer of the absorbent product. The absorbent core includes a pair of arm portions and a pair of leg portions, with the arm and leg portions protruding laterally and longitudinally from a central portion of the absorbent core.2013-06-27
20130165887PACKAGE COMPRISING PEELABLE OVERLABEL - Packages for containing consumer goods are disclosed. The consumer goods may be disposable, durable or semi-durable. Absorbent article is one class of disposable articles that may be contained by packages. The packages comprise an opening that is covered by an overlabel. The overlabel is at least partially peeled off of the package so that articles contained within the package can be removed through the now exposed opening. In some embodiments, the package can be reclosed by covering the opening with the overlabel. A consumer may wish to dispose of a used article by placing the article back into the package via the opening and re-adhering the overlabel.2013-06-27
20130165888PACKAGE STRUCTURE - A package structure that includes wings that extend from both sides in the width direction provided on an absorbent article. On first regions on the clothing side of the wings and second regions on the clothing side of the backing sheet, adhesive for affixing the absorbent article to underwear is applied. With the wings folded toward the skin-contacting side of the surface sheet, a water-degradable release sheet is provided so as to cover the first regions. Wrapping sheet is non-water-degradable, is peelable from the underwear-affixing adhesive and is provided so as to cover the second regions.2013-06-27
20130165889INCONTINENCE LINER - An incontinence liner includes a liquid permeable skin contact side sheet, a liquid impermeable non-skin contact side sheet, and an absorptive body arranged between the skin contact side sheet and non-skin contact side sheet. The absorptive body includes a front region, a rear region, and an intermediate region between the front region and the rear region. The liner further has a pair of wings for fastening the liner to clothing, which are adjoining the intermediate region and are bent and superposed over the intermediate region when worn. The absorptive body includes a hygroscopic material. The basis weight of the hygroscopic material in the intermediate region is greater than the basis weight of the hygroscopic material in the front region and the basis weight of the hygroscopic material in the rear region.2013-06-27
20130165890Disposable Absorbent Product with Elastic Leg Opening Regions and Related Methods - A disposable absorbent product extends along a longitudinal dimension and a width dimension. The absorbent product has a backsheet, a topsheet overlaying the backsheet, and an absorbent core that is disposed between the backsheet and the topsheet for absorbing and retaining fluid secreted by a wearer of the absorbent product. The absorbent product also has a first multidirectional stretch material layer, adjacent the backsheet, that defines a first contoured leg opening of the absorbent product adapted to fit around a first leg of the wearer of the absorbent product.2013-06-27
20130165891Tampon - A pledget for a tampon having improved leakage prevention of bodily fluid after the tampon is inserted in the vagina. The pledget has a contact member in communication with the absorbent core of the pledget. The contact member can have a contact element which can expand outward from the pledget upon contact with bodily fluid.2013-06-27
20130165892Fluid Management Device with Fluid Transport Element for use within a Body - A fluid management device for use in a mammalian body has at least one fluid transport element capable of interfacing with a mammalian body element to provide a substantially uninterrupted fluid conduit. The fluid conduit provides a fluid path between at least one fluid transport element and the storage element. A distal portion of the at least one fluid transport element is capable of extending away from the fluid storage element, and the at least one fluid transport element has a Wing Stiffness of less than about 10 g2013-06-27
20130165893TAMPON WITH FLEXIBLE PANELS - An intravaginal device has a fluid storage element having a longitudinal axis and is in fluid communication with at least one flexible panel.2013-06-27
20130165894TAMPON WITH FLEXIBLE PANELS - An intravaginal device has a fluid storage element having a longitudinal axis and is in fluid communication with at least one flexible panel.2013-06-27
20130165895PANT-TYPE ABSORBENT ARTICLE - A pant-type absorbent article having an absorbent assembly having an absorbent core and a chassis, wherein the front and back portions are joined to each other along two opposite longitudinal side edges to define a waist-opening and a pair of leg-openings, at least one of the front and back portions has an elastic web material, a crotch portion located between the front portion and the back portion in the longitudinal direction of the article, the front portion having a length in the longitudinal direction, the back portion having a length in the longitudinal direction, and the crotch portion having a length in the longitudinal direction, the absorbent assembly overlapping a distance with both the front and back portions, the article having a longitudinal and a transverse direction, wherein the absorbent assembly overlaps no more than 20% of the surface area of each of the front and back portions.2013-06-27
20130165896DISPOSABLE ABSORBENT PRODUCT WITH BONDED LATERAL REGIONS AND RELATED METHODS - A disposable absorbent product extends along a longitudinal axis and a transverse axis orthogonal to the longitudinal axis. The product has a topsheet, and a backsheet overlaying the topsheet, with the topsheet and backsheet jointly defining first and second side edges of the product on respective sides of the longitudinal axis. An absorbent core is disposed between the topsheet and the backsheet for storing fluid secreted by the wearer of the product. The absorbent core has first and second lateral edges respectively inboard of the first and second side edges of the product so as to define respective first and second lateral portions of the product that are free of the absorbent core. The product also has a plurality of folds parallel to the transverse axis, and a plurality of bonds in at least one of the first or second lateral portions that secure the plurality of folds in place.2013-06-27
20130165897DISPOSABLE ABSORBENT PRODUCT WITH FASTENING COMPONENTS AND RELATED METHODS - A disposable absorbent product extends along a longitudinal axis between front and back longitudinal ends of the product, and along a transverse axis. The product has a topsheet defining an interior face of the product configured to face a wearer thereof during use, and a backsheet overlaying the topsheet, the backsheet defining an exterior face of the product. An absorbent core is disposed between the topsheet and the backsheet for storing fluid secreted by the wearer of the product. The product also includes a first pair of fastening components, each being formed from a partially cut-out portion of the disposable absorbent product so as to be pivotally coupled to a remainder of the product, such that pivotal movement of the fastening components relative to a remainder of the product defines at least one aperture that extends between the interior and exterior faces of the product.2013-06-27
20130165898REFASTENABLE DISPOSABLE GARMENT HAVING A CURLED EDGE, AND PROCESS FOR MAKING SAME - A refastenable disposable garment defines a longitudinal direction and a transverse direction, and comprises a first waist region contiguous with a first waist edge. The first waist region defines first and second side edges transversely spaced apart and defines first and second surfaces. The first waist region is elastomeric proximal both the first and second side edges. The garment can include a second waist region and a crotch region that interconnects the first and second waist regions. The garment comprises non-extensible, relatively rigid first and second fastening components attached to the first surface of the first waist region adjacent the first and second side edges, respectively. The first waist region defines first and second flange portions transversely outward of the first and second fastening components, respectively. Each flange portion is transversely curled toward the second surface. A process for making such an article is also disclosed.2013-06-27
20130165899DOSING UNIT, AMBULATORY INFUSION DEVICE COMPRISING DOSING UNIT AND METHOD FOR OPERATING A DOSING UNIT - A dosing unit for an ambulatory infusion device and a method of operation are disclosed. The dosing unit includes a stationary member, a movable member, and a plunger. The movable member and the stationary member, together, make a charging valve and a discharging valve. The plunger is located, at least in part, in a metering cavity of the movable member and the movable member is adapted to selectively couple and decouple a driving unit, such that, by operating the driving unit with the movable member being coupled with the driving unit, the movable member moves with the plunger to maintain a position of the plunger relative to the movable member along a displacement axis, and by operating the driving unit with the movable member being decoupled from the driving unit, the plunger is displaced while the position of the movable member is maintained.2013-06-27
20130165900FLUID COMPONENT ANALYSIS SYSTEMS AND METHODS FOR GLUCOSE MONITORING AND CONTROL - Disclosed are methods and apparatus for determining analyte concentration in a sample such as bodily fluid. Systems and methods disclosed herein can also include a treatment dosing system to infuse or inject a treatment drug (e.g., insulin or glucose) and provide glycemic control. The dose of the treatment drug may be based on the concentration of the analyte or the average value for the concentration of the analyte and/or the rate of change of the value of the concentration of the analyte.2013-06-27
20130165901SYSTEMS AND METHODS FOR DETERMINING INSULIN THERAPY FOR A PATIENT - In example methods and systems described, insulin therapy for a patient can be determined. At least one of a short-acting subcutaneous insulin dosage recommendation, a correction subcutaneous insulin dosage recommendation, an intravenous insulin dosage recommendation, a recommended amount of carbohydrates to be administered to the patient, or combinations thereof, can be determined. In addition, information indicating a confirmation of a nutrition intake for the patient, and a long-acting insulin-on-board for the patient can be received, and based on this information, a required long-acting subcutaneous or intravenous insulin dosage for the patient can be determined. The short-acting subcutaneous or intravenous insulin dosage recommendation can be adjusted based, at least in part, on a difference between the long-acting insulin-on-board and the required long-acting subcutaneous or intravenous insulin dosage.2013-06-27
20130165902MICRONEEDLE ARRAY APPLICATOR AND METHOD FOR APPLYING A MICRONEEDLE ARRAY - A microneedle array applicator is configured to apply a microneedle array in cosmetic and medical applications. The microneedle array applicator has a holding apparatus configured to define detachable holding of a microneedle array comprising a planar substrate. The microneedle array applicator also has a drive mechanism for driving the microneedle array in a first direction perpendicular to the planar substrate and in a second direction parallel to the planar substrate. A method for applying a microneedle array includes the microneedle array applicator enabling safe breaking off of the microneedles, optionally laden with an active ingredient, in the skin.2013-06-27
20130165903METHOD AND APPARATUS FOR CONTROLLED OCCLUSION - A controlled volume inflation-deflation device to inflate a balloon to occlude a blood vessel by dialing a knob that locks at rotational positions to locate a plunger at equally spaced locations within a syringe of the inflation-deflation device. The inflation-deflation device includes a releasable latch to lock the proximal and distal housings together to hold the plunger forward for occlusion, and to separate and hold the proximal and distal housings to retract the plunger for perfusion. When the inflation-deflation device is returned to the latched position, the balloon is re-inflated to its previous occlusive diameter. Also, an extension tube made of a lower modulus outer material co-extruded over and miscible with a higher modulus inner material may be used to produce a suitably low compliance extension tube for the inflation-deflation device. The balloon may have tapered ends and a cylindrical center portion so that it increases by more equal increments in outer diameter in response to incremental equal increases in inflation volume.2013-06-27
20130165904Apparatus and Method Pertaining to the Monitoring of Injection Pressure During Administration of Nerve Blocks - A control circuit that operably couples to a display and to a nerve block injection pressure sensor provides a display of both a current nerve block injection pressure value and a current nerve block injection pressure categorical range. That categorical range can comprise, for example, one of a plurality of available categorical ranges which may be visually differentiated from one another by color. The control circuit can also detect (and display) a maximum nerve block injection pressure value (and/or calculate a mean nerve block injection pressure value) as corresponds to a given monitored nerve block injection procedure. The control circuit can also detect negative nerve block injection pressure events and identify those events as aspiration events to facilitate keeping a count of aspiration events during the course of a given nerve block injection procedure. The control circuit can also help ensure observe of the proper patient laterality if desired.2013-06-27
20130165905Stretch Valve Balloon Catheter and Methods for Producing and Using Same - A safety catheter includes a flexible, multi-lumen shaft having an outer diameter, a distal tip, a proximal catheter end with a drain end and a proximal inflation end. The multi-lumen shaft defines a drain lumen, a distal hollow balloon portion, at least one inflation lumen, and a drainage port. A hollow stretch valve is coaxially disposed in the inflation or drainage lumen, or both, has a fixed portion within the inflation or drainage lumen, or both, and prevents fluid from passing through the drainage port in a steady state and has a sliding portion slidably disposed within the inflation or drainage lumen, or both, such that, in a stretched state when the proximal catheter end is stretched, the sliding portion slides within the inflation or drainage lumen, or both to permit fluid to pass through the balloon drainage port and/or wall of the catheter.2013-06-27
20130165906ADMINISTRATION APPARATUS, OPERATING METHOD THEREOF AND ADMINISTRATION METHOD - An administration apparatus to administer an inhibitor drug to a patient to inhibit cell division of a malignant cell includes an administration unit configured to administer the inhibitor drug to the patient; an administration timing storage unit configured to store an administration time to start an administration of the inhibitor drug; a time measurement unit configured to measure a current time; and a control unit configured to drive and control the administration unit so as to administer the inhibitor drug to the patient when the current time coincides with the administration time. The administration time is set on a basis of a pre-determined phase of a cell cycle of the malignant cell.2013-06-27
20130165907INSTRUMENT WITH REMOVABLE TIP - A laparoscopic instrument is disclosed, including an elongated tube defining a proximal portion and a distal portion; an end effector removably coupled to the distal portion, the end effector including first and second elements pivotably coupled to one another; an anchor coupled to the tube and a pivot point of the end effector to restrict axial movement of the end effector; and a sleeve movably coupled to the tube, where the sleeve is slidable across at least a portion of the end effector to secure the end effector to the tube.2013-06-27
20130165908POSITIONING DEVICE AND ARTICULATION ASSEMBLY FOR REMOTE POSITIONING OF A TOOL - A device for use in guiding the position of a surgical tool from a remote location is disclosed. The device includes a handle, an elongate shaft mounted on the handle, an elongate articulation assembly carried at its proximal end to the shaft and adapted to receive the surgical tool at the assembly's distal end, and a cable operatively connecting the handle to the articulation assembly. The position of the articulation assembly is controlled by rotating a knob on the handle, which moves the articulation into different angled configurations depending on whether the knob is rotated in clockwise or counterclockwise directions.2013-06-27
20130165909OPERATING ELEMENT FOR MEDICAL, PREFERABLY SURGICAL INSTRUMENTS WITH THREE-FINGER HOLD - An instrument includes a motor unit with a slide or piston. The operating direction of the slide or piston may be adapted to the bending and stretching movement of the user's index finger. A resiliently elastic extension or tongue transfers the bending and stretching movement of the index finger to the slide or piston on the side of the motor unit. The tongue is fixedly coupled to the slide or piston and extends above the handpiece along a gripping portion. The resilient flexibility of the tongue is selected so that it can be easily bent by the index finger resting on the tongue toward the gripping portion of the handpiece, which then serves as a contact or stop element for an operating element at the tongue and thus ensures fixed clamping of the handpiece between the thumb, the middle finger and the index finger.2013-06-27
20130165910STEERABLE LASER PROBE - A steerable laser probe may include a handle, an actuation structure of the handle, a housing tube, a flexible tube, an optic fiber, and a wire having a pre-formed curve. The flexible tube may be disposed within the housing tube wherein a distal end of the flexible tube projects out from a distal end of the housing tube. The optic fiber may be disposed within an inner bore of the handle, the housing tube, and the flexible tube. The wire may be disposed within the housing tube.2013-06-27
20130165911Patient Interface With Variable Applanation - A variable-applanation patient interface can include a lens support system, attachable to a distal end of an ophthalmic surgical laser system; a contact lens, supported by the lens support system and configured to make contact with an eye-surface; and an adjustable coupler, coupled to at least one of the lens support system and the contact lens, and configured to be coupled to a non-central region of the eye-surface, to accommodate the contact lens to contact a central region of the eye-surface with a central applanation, to enable a change between the central applanation and an extended applanation, and to accommodate the contact lens to contact an extended region of the eye-surface larger than the central region with the extended applanation.2013-06-27
20130165912Hair Treatment System and Method - A hand held device generates a predetermined number of pulses of electromagnetic radiation having a predetermined electromagnetic spectrum, a predetermined duration, a predetermined inter-pulse interval, and a predetermined total energy. The pulse sequence is delivered to a skin surface to reduce or eliminate Xray or ultraviolet radiation damage to the skin surface.2013-06-27
20130165913MOISTURE TRANSPORT SYSTEM FOR CONTACT ELECTROCOAGULATION - An apparatus and method for use in performing ablation or coagulation of organs and other tissue includes a metallized fabric electrode array which is substantially absorbent and/or permeable to moisture and gases such as steam and conformable to the body cavity. The array includes conductive regions separated by insulated regions arranged to produce ablation to a predetermined depth. Following placement of the ablation device into contact with the tissue to be ablated, an RF generator is used to deliver RF energy to the conductive regions and to thereby induce current flow from the electrodes to tissue to be ablated. As the current heats the tissue, moisture (such as steam or liquid) leaves the tissue causing the tissue to dehydrate. Suction may be applied to facilitate moisture removal. The moisture permeability and/or absorbency of the electrode carrying member allows the moisture to leave the ablation site so as to prevent the moisture from providing a path of conductivity for the current.2013-06-27
20130165914BALLOON CATHETER - Thermal conduction to a non-target tissue is unfailingly blocked off to select and effectively ablate only a target tissue. A catheter shaft 2013-06-27
20130165915ENERGY DELIVERY SYSTEMS AND USES THEREOF - The present invention relates to comprehensive systems, devices and methods for delivering energy to tissue for a wide variety of applications, including medical procedures (e.g., tissue ablation, resection, cautery, vascular thrombosis, treatment of cardiac arrhythmias and dysrhythmias, electrosurgery, tissue harvest, etc.). In certain embodiments, systems, devices, and methods are provided for treating a tissue region (e.g., a tumor) through application of energy.2013-06-27
20130165916METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example method may include a method for treating tissue near a body passageway using an apparatus including a catheter having a plurality of electrodes, a radio-frequency energy generator, and a controller coupling the energy generator to the plurality of electrodes and configured to selectively energize the electrodes. The method may include using the apparatus to subject the tissue near the body passageway to a plurality of energy treatment cycles. The treatment cycle may include determining desired voltages for at least a subset of the electrodes for maintaining a predetermined target temperature profile proximate the subset of electrodes, setting an output voltage of the energy generator to correspond to the desired voltage determined for one of the electrodes, and energizing at least some of the electrodes at the output voltage to deliver energy to the body passageway.2013-06-27
20130165917METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example method may include renal-denervation treatment method. The method may include delivering an RF energy treatment to a tissue proximate a renal artery using a catheter assembly of a renal denervation catheter system. The denervation system may include an RF energy generator coupled with the catheter assembly by a controller. The method may also include applying neural activity stimulation to the tissue proximate the renal artery using the catheter assembly, assessing stimulated neural activity response of the tissue using the catheter assembly, and determining a parameter of the RF energy treatment based on the assessed neural activity.2013-06-27
20130165918ELECTROSURGERY DETECTION - A device includes a plurality of electrodes and a detection module. The plurality of electrodes are configured to acquire an electrical signal in a patient. The detection module is configured to determine whether the acquired electrical signal includes signal content in each of N different frequency bands and detect operation of an electrosurgical device on the patient based on how many of the N different frequency bands include signal content. N is an integer that is greater than 1.2013-06-27
20130165919IMPEDANCE RESPONSIVE ABLATION RF DRIVING FOR MODERATING RETURN ELECTRODE TEMPERATURE - The inventive method for ablating a tissue mass associated with a human or animal patient being treated comprises positioning an ablating electrode in a tissue mass to be ablated. A plurality of return electrodes are positioned on the patient. Electrical energy is applied between the return electrodes and the ablating electrode. The temperature of the return electrodes is measured to generate a temperature measurement signal which is used to control ablation current through the return electrodes.2013-06-27
20130165920NERVE MODULATION SYSTEM HAVING HELICAL GUIDE - Systems for nerve modulation and methods for making and using the same are disclosed. An example system for nerve modulation may include a first elongate element having a distal end and a proximal end and having a helical guide having a proximal end and a distal end. The system may also include a second elongate element having a distal end and a proximal end and having a nerve modulation element proximate the distal end. A sheath may be disposed about both the first and second elongate elements. Pulling proximally on the proximal end of the first elongate element may cause simultaneous radial and longitudinal displacement of the nerve modulation element.2013-06-27
20130165921DEVICE AND METHODS FOR NERVE MODULATION - The disclosure pertains to an intravascular system for nerve modulation through a wall of a blood vessel and methods of use therefor, wherein the system is capable of nerve modulation by one or more ablations of a blood vessel adjacent to the nerve to be modulated. The intravascular system is suited for modulation of renal nerves.2013-06-27
20130165922ELECTROPHYSIOLOGY LOOP CATHETER - A catheter including control, localization, and/or fluid delivery features, and methods of using the same. One embodiment is directed to an electrophysiology catheter including a superelastic wire and a cable, and a method of controlling the catheter using the cable. Another embodiment is directed to an electrophysiology catheter including an adhesive to bias the orientation of the catheter. A further embodiment is directed to an electrophysiology catheter including adhesive and one or more cables, and a method of controlling the catheter using the one or more cables. Another embodiment is directed to a method including acts of injecting a fluid into the heart of a patient and adjusting the diameter of an arcuate curve of the catheter. Further embodiments are directed to a catheter having multiple position sensors on an arcuate curve of the catheter, or a position sensor associated with a movable electrode of the catheter.2013-06-27
20130165923METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example device may include a catheter extending along a longitudinal axis. A balloon may be coupled to an end of the catheter. The balloon having a plurality of cylindrical treatment zones extending along the longitudinal axis in an expanded state. A plurality of electrode assemblies may be coupled to the balloon. Each electrode assembly may include a distal electrode pad and a proximal electrode pad.2013-06-27
20130165924METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example device may include an expandable balloon including an outer surface. At least one flexible circuit may be mounted on the outer surface of the expandable balloon. The at least one flexible circuit may include a first insulating layer, at least one heat sensing device positioned at least partially within the first insulating layer, a conductive layer above the first insulating layer, at least a portion of which is electrically coupled to the heat sensing device, a second insulating layer above the conductive layer, and at least one electrode associated with the conductive layer.2013-06-27
20130165925METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example medical device may include a catheter. The catheter may include an elongate flexible catheter body. An expandable structure may be associated with the catheter body and may include a radially expandable balloon and a plurality of flexible circuits extending along an outer surface of the balloon. Each flexible circuit may include at least one electrode and at least one temperature sensor. The expandable structure may have an outer diameter of less than 4 mm when in an expanded configuration.2013-06-27
20130165926METHODS AND APPARATUSES FOR REMODELING TISSUE OF OR ADJACENT TO A BODY PASSAGE - Medical devices and methods for making and using the same are disclosed. An example medical device may include a catheter shaft. An expandable member may be coupled to the catheter shaft. A plurality of flexible electrode assemblies may be coupled to the expandable member. A control unit may be coupled to the electrode assemblies. The control unit may be configured to energize the electrode assemblies for approximately 10 seconds to less than approximately 1 minute.2013-06-27
20130165927SURGICAL CLAMP HAVING TREATMENT ELEMENTS - A medical device is provided having a means for actuating a pair of opposing jaw members. The jaw members are movable relative to one another from a first position, wherein the jaw members are disposed in a spaced apart relation relative to one another, to a second position, wherein the jaw members cooperate to grasp tissue therebetween. An ablation tool is connected to at least one of the jaws members, such that the jaw members are capable of conducting ablation energy through the tissue grasped therebetween.2013-06-27
20130165928Systems and Methods Employing Radiofrequency Energy for Skin Treatment - This disclosure relates generally to electrosurgical methods and devices. In one embodiment, an electrosurgical device is provided suitable for applying phase controlled RF energy to a treatment site. The electrosurgical device comprises a multi-electrode electrosurgical probe electrically coupled to a plurality of RF generators. Also provided are methods of use of such an electrosurgical device, as well as other electrosurgical devices. The methods and devices disclosed herein find utility, for example, in the field of medicine.2013-06-27
20130165929HAND ACTIVATED SURGICAL INSTRUMENT - An electronic circuit assembly for use with a hand-held surgical instrument including a housing that accepts a detachable handpiece for providing ultrasonic energy, a first and second user-controlled power activation member for controlling the level of ultrasonic energy, a handpiece connector configured to electrically connect the handpiece to the electronic circuit assembly. The handpiece connector allows the handpiece to rotate about a longitudinal axis of the housing and maintain continuous electrical contact between the handpiece and the electronic circuit assembly.2013-06-27
20130165930BOLT AND TOOL WITH ANTI-TORQUE FEATURES - A system for fixing a wire to a surface of an external fixator having a wire adapted to extend through bony structure fastened with respect to the surface. A bolt having a shaft which comprises a threaded section, a head section and at least one clamping element is provided wherein the bolt is adapted to extend through an opening in the external fixation element with a nut, and clamps the wire to the surface. A counter torque tool is used to provide a counter torque while fastening the wire with the bolt and the nut. The bolt comprises a counter torque opening and wherein the counter torque tool comprises a section which is adapted to engage into the counter torque opening of the bolt to apply the counter torque.2013-06-27
20130165931OUTRIGGER WITH LOCKING MECHANISM - A method is for connecting an outrigger to a clamp in an external fixation system. A moveable member and a slide lock are couplied to an elongated member of the outrigger. The elongated member has a length, a distal end, a proximal end and a threaded portion on the distal end. The threaded portion has a keyed portion. The moveable member is moveable along the elongated member. The slide lock has a keyed portion and an engagement surface. The distal end of the elongated member is coupled to an opening of the clamp such that the engagement surface of the slide lock engages a portion of the clamp. The keyed portion of the threaded portion and the keyed portion of the slide lock are operably associated with each other to permit longitudinal movement of the slide lock along the length of the elongated member while preventing rotation. The engagement surface of the slide lock has a non-smooth texture and faces in a direction that is away from the moveable member.2013-06-27
20130165932FIXATION CLAMP WITH THUMBWHEEL - A fixation clamp, more particularly for use in an external fixation system for holding bone fragments adjacent to each other with the help of fixation elements, has at least one clamping assembly having at least one reception opening to accommodate a fixation element along the longitudinal axis of the reception opening. At least one locking element extends through the clamping assembly which locking element provides a clamping force to clamp the fixation element upon tensioning the locking element. The fixation clamp further comprises an actuation element which is in connection with the locking element such that the locking element is actuateable by means of the actuation element, and the actuation element is designed such that it is detachable from the locking element after use and that remounting onto the locking element is prevented after having detached the actuation element from the locking element.2013-06-27
20130165933BONE PLATE SYSTEM AND METHOD - In one aspect, a bone plate system is provided including a bone plate and a plurality of cable connector devices configured to be inserted into throughbores formed in bone portions and through openings of the bone plate member aligned therewith. The cable connector devices each include opposite end portions with one end portion configured to abut against the bone adjacent the throughbore and the other end portion configured to be operatively fixed to the bone plate member with the cable portion extending therebetween and in the bone throughbore for securing the bone plate member to the bone portion with the cable connector devices including a cable portion thereof extending in the bone throughbore.2013-06-27
20130165934Static Compression Device - A device for compressing two or more adjacent bones includes a male plate attachable to a first one bones and having a central protrusion extending away from the male plate along a longitudinal axis, a female plate attachable to a second one of the bones and having a channel substantially parallel to the longitudinal axis and adapted to conformally receive the central protrusion when the plates are aligned, and a locking mechanism configured to: hold the male plate and the female plate together when the plates are aligned; allow the male plate and the female plate to move with respect to each other under compression along the longitudinal axis when the protrusion is engaged with the channel; and prevent movement of the male plate with respect to the female plate when a desired, measurable amount of force is applied to the first bone with respect to the second bone.2013-06-27
20130165935EXPANDABLE RETROGRADE DRILL - An orthopedic reamer, including a first shaft; a second shaft movably disposed within at least a portion of the first shaft; a handle movably coupled to at least one of the first or second shafts; a drilling element coupled to a distal portion of the second shaft; and a plurality of cutting elements, each cutting element having a first portion connected to the first shaft and a second portion connected to the second shaft. The plurality of cutting elements are controllably transitionable from i) a substantially linear configuration parallel to the first and second shafts to ii) an angled configuration with respect to the first and second shafts.2013-06-27
20130165936SYSTEM AND METHOD FOR A MODULAR RESECTION GUIDE - A modular bone resection guide system includes a positioning base configured to be attached to a bone, a modular resection block configured to be removably attached to various locations of the positioning base and a cutting tool configured to be supported and guided by the modular resection block while cutting the bone.2013-06-27
20130165937SURGICAL NAVIGATION - A method of surgical navigation into the brain includes establishing a trajectory through the skull into the brain to a target, drilling a hole in the skull using a drill, and verifying the trajectory of the drilled hole during drilling using image guidance. A surgical navigation system includes a cannulated drill, a cannulated access member, and a coupling member for coupling the access member to the drill and for maintaining alignment of the cannulations in the drill and the access member. The access member is movable relative to the coupling member such that the access member can be secured to tissue while the coupling member maintains the alignment of the cannulations. A surgical kit includes a cannulated drill, a cannulated access member, a coupling member for coupling the access member to the drill, and a probe for receipt within the cannulated drill.2013-06-27
20130165938PROSTHETIC FEMORAL STEM FOR USE IN HIGH IMPACT HIP REPLACEMENT - A total hip femoral prosthesis provides a shortened neck and more proximal coating level. Additionally, a means for strengthening the neck may be incorporated to increase stress transfer to the native bone. A method for reducing potential impingement that results from a high neck resection level includes instrumentation for cutting chamfered surfaces into the bone surrounding the proximal end of the implant. Instrumentation and methods of creating chamfered cuts are disclosed.2013-06-27
20130165939Patient Specific Implants and Instrumentation For Patellar Prostheses - Patient specific implants and instrumentation for replacing a portion of a patella. Methods for producing patient specific implants and instrumentation include conducting imaging studies of the patient's native patella, deriving measurements of the patella and surrounding soft tissues from the imaging studies, manufacturing customized implants and instrumentation specific to the derived measurements, and implanting a customized implant using the customized instrumentation. Patient specific instrumentation includes: a patellar clamp ring, an anterior clamp, a restraining arm, a posterior clamping surface, a dual bore reaming collet, a reamer, a reaming depth gauge, and a resection cutting guide. Patient specific portions of a patellar implant include: topography of the posterior articular surface, facet angle, shape and dimensions of the anterior attachment surface, implant length, implant width, implant thickness and the outer perimeter shape of the implant.2013-06-27
20130165940METHOD AND APPARATUS FOR USE IN BALANCING LIGAMENTS OF A KNEE - An orthopaedic surgical instrument includes an orthopaedic distraction device sized to be positioned between a distal end of a patient's femur and a proximal end of the patient's tibia and configured to apply force between the patient's femur and the patient's tibia. The orthopaedic surgical instrument also includes a user-operated control device operable to actuate the orthopaedic distraction device to apply force between the patient's femur and the patient's tibia. In actuating the orthopaedic distraction device, a rotary input of the user-operated control device that is coupled to the orthopaedic distraction device may be used. The orthopaedic surgical instrument also includes a display positioned on an outer surface of the orthopaedic distraction device and a circuit configured to control the display. The display is configured to provide visual feedback indicative of force applied by the distraction device.2013-06-27
20130165941GUIDE FOR ACETABULAR COMPONENT POSITIONING - Apparatus for aligning a surgical instrument, such as an acetabular cup inserter, with a direction guide that defines an orientation in space for insertion of the cup. The apparatus comprises a parallel guide having a first arm for alignment with the direction guide and a second arm spaced from the first arm but maintained in parallel relationship with it. The cup inserter can be aligned with the first arm by aligning it with the second arm.2013-06-27
20130165942Length-Adjustable Vertebral Body Balloon - A length-adjustable vertebral body balloon catheter in which the location of the balloon can now be manipulated once an access cannula has been placed in the vertebral body. The device includes a collet such as a Touhy-Borst valve that allows the clinician2013-06-27
20130165943INTRAOCULAR LENS SURGICAL SYSTEM AND METHOD - Various systems, apparatuses, and processes may be used for performing intraocular lens surgery. In some implementations, a system for intraocular lens surgery may include a first body, a second body, and flexible joint. The first body may be adapted to receive an intraocular lens, and the second body may include a passage adapted to facilitate folding the intraocular lens as the lens is advanced through the passage. The flexible joint may be interposed in a gap between the first body and the second body.2013-06-27
20130165944APPARATUS, SYSTEMS, AND METHODS FOR REMOVING OBSTRUCTIONS IN THE URINARY TRACT - Systems and methods are provided for removing an obstruction from a ureter using a catheter including a distal end sized for introduction into a ureter, an infusion lumen, and an aspiration lumen. An infusion tip is provided on the distal end that includes infusion ports communicating with the infusion lumen, and one or more aspiration ports communicating with the aspiration lumen. One or more sources of fluid and/or vacuum are connectable to the tubular member such that fluid is delivered into the infusion lumen and suction is delivered into the aspiration lumen. A controller is coupled to the source(s) to control delivery of fluid to generate a radially outward pressure against a wall of a ureter adjacent the infusion tip and to control suction through the aspiration port(s) to apply a suction force against a kidney stone located adjacent the infusion tip.2013-06-27
20130165945METHODS AND DEVICES FOR CONTROLLING A SHAPEABLE INSTRUMENT - Systems and methods are described herein that improve control of a shapeable or steerable instrument using shape data. Additional methods include of controlling a shapeable instrument within an anatomical region using a robotic medical system.2013-06-27
20130165946APPARATUS FOR A ROBOTIC CONTROL AND GUIDANCE SYSTEM - An apparatus for a robotically controlled medical device guidance system comprises a manipulator assembly and a medical device cartridge. The manipulator assembly includes a housing, an electrical port having a first end configured for mating with a complementary electrical connector of a cable, and a manipulation base disposed within the housing and including an electrical interface. The electrical interface is electrically connected to a second end of the electrical port. The cartridge is configured to be removably attached to the manipulation base. The cartridge includes an electrical interface configured to electrically contact the electrical interface of the manipulation base when the cartridge is attached to the base, and a medical device associated therewith. The medical device includes a sensor and a corresponding lead wire. The lead wire is electrically connected to and between the sensor and the electrical interface of the cartridge.2013-06-27
20130165947CONNECTION METHOD FOR MEMS NAVIGATION UNIT FOR COMPUTER-ASSISTED SURGERY - A computer-assisted surgery (CAS) navigation assembly comprises a micro-electromechanical sensor (MEMS) navigation unit having one or more MEMS to provide at least orientation data. A support receives the MEMS navigation unit therein, the support being adapted to be mounted on the instrument in a fixed orientation relative to established navigated features of the instrument. At least two mating ball-in-socket features are disposed between the MEMS navigation unit and the support at opposed ends thereof for releasably engaging the MEMS navigation unit in precise orientational alignment within the receptacle, the at least two mating ball-in-socket features comprising catches aligned along an axis extending between the opposed ends, at least one of the catches being a biased catch. A method of connecting a MEMS navigation unit with a mating support fixed to a CAS instrument navigated by the CAS system is also provided.2013-06-27
20130165948ROBOTIC CONTROL OF AN ENDOSCOPE FROM BLOOD VESSEL TREE IMAGES - A robot guiding system employs a robot unit (2013-06-27
20130165949SOFT TISSUE COAPTOR AND DEVICE FOR DEPLOYING SAME - A soft tissue coaptor and a soft tissue coaptor deployment device are disclosed which deliver a soft tissue coaptor or clip to a desired location for tissue repair. The soft tissue coaptor and soft tissue coaptor deployment device have particular application in surgical and microsurgical settings such as cardiac, vascular, and ophthalmic surgery.2013-06-27
20130165950SYSTEM AND METHOD TO ACHIEVE RECIPROCATING ROTATIONAL MOTION OF THE DISTAL MEMBER OF A DEVICE BY APPLYING TRANSLATIONAL FORCES - A medical device includes an elongate body extending from a proximal portion which, in an operative configuration, remains outside a living body, to a distal end which, in the operative configuration, extends through a body to a position adjacent to a target portion of tissue to be treated and a spool rotatably coupled to the distal portion of the elongate body, the spool including a distal portion coupled to an end effector of the device along with a flexible member extending from the proximal portion of the elongate body, a first portion of the flexible member being wound about the spool in a first direction and a second portion of the flexible member wound about the spool in a second direction opposite the first direction, ends of the first and second portions extending to the proximal portion of the elongate body.2013-06-27
20130165951Surgical clip applier - A surgical clip applier with scissor-type operating handle and clip applying cartridge in which handle has housing of upper and lower shells that defines socket for receiving cartridge, includes a lever arm actuated linear translator for linear reciprocating movement delivered to the cartridge, and an anti-backup mechanism for full forward and release strokes of the handle, and in which cartridge includes jaws for applying clips, safety means to ensure opening of jaws for each cycle, a puller bar for receiving motion from handle and timing of jaw operation to clip feed, a magazine for feeding clips to jaws in proper sequence, and a lockout mechanism to render applier inoperative after using last clip.2013-06-27
20130165952ARTICULATING CLIP APPLIER CARTRIDGE - An end effector is provided and includes a distal housing portion and a proximal housing portion interconnected to one another by a knuckle portion, wherein the knuckle portion permits rotation of the distal housing portion relative thereto and articulation of the distal housing portion relative to the proximal housing portion; a jaw assembly supported in the distal end of the distal housing portion, the jaw assembly including a first jaw and a second jaw movable between a spaced apart and an approximated position; and a plurality of fasteners loaded within the distal housing portion, each of the plurality of fasteners defining a fastener axis extending in a direction substantially parallel to a pair of legs thereof, each of the plurality of fasteners being arranged within the base portion such that the fastener axis is disposed at an angle with respect to a longitudinal axis of the distal housing portion.2013-06-27
20130165953SUTURE CLIP DEPLOYMENT DEVICES - Suture clip deployment devices for applying suture clips to sutures are described. Some embodiments can include a generally tubular main body and a vacuum port located at the distal end, a hollow inner body longitudinally slidable within the main body and extending from the main body at its distal end, and a suture recess located in the generally tubular main body. At least one suture clip configured to frictionally fit on an outer surface of the inner body is deployed during use. Clip deployment can occur after a vacuum source is applied to the device so as to draw the suture into the device. The suture lines can be retrieved through the suture recess, and the device can be actuated so as to deliver the suture clip off the delivery device and onto the suture, locking the suture in place.2013-06-27
20130165954CONTINUOUS SUTURE PASSING INSTRUMENT - Suture passing devices that may be used in both open and endoscopic surgical procedures and that are designed to continuously deploy suture. The surgical device is provided with a handle assembly including an actuator in communication with a pair of advancement wheels and a built-in spool of suture (with a long length of material that can be fed through tissue and cut at desired locations). By moving the actuator linearly, the advancement wheels rotate, causing the spool to rotate and advance the suture through a shaft of the instrument to the tissue to be sutured, in a continuous manner.2013-06-27
20130165955ENDOSCOPIC FASCIAL CLOSURE SYSTEMS AND METHODS FOR USING SAME - A system for closure of a fascial opening is disclosed. The system may include a first capture device for pulling one end of a suture through fascial tissue on one side of a fascial opening, and a second capture device for pulling an opposing end of the suture through the fascial tissue on an opposite side of the fascial opening. A trapping device for locating and engaging the first capture device can be used, prior to the capture device being pulled through the fascial tissue, so that the trapping device can subsequently pull the suture to facilitate closure of the fascial opening. Methods and apparatuses for closure of a fascial opening are also disclosed.2013-06-27
20130165956Suture Passer Guides and Related Kits and Methods - A suture passer guide that includes an elongate member having a longitudinal axis and defining a first proximal opening and a first distal opening. The first proximal and distal openings are substantially aligned with one another such that a suture passer can be extended through the first proximal and distal openings at an acute angle relative to the longitudinal axis of the elongate member. The suture passer guide can be configured to be passed through a central lumen of an endoscopic port.2013-06-27
20130165957Implantable Prosthetic Devices and Solvent-Casting Methods for Manufacturing Same - Implantable prosthetic devices are provided. Such devices include substantially planar supports such as a mesh for surgical use made of polypropylene, and a porous coating membrane formed on at least one face of said support, said porous membrane being formed in situ on the support by the solvent casting technique. Methods for making such prosthetic devices are also provided.2013-06-27
20130165958INTRAVASCULAR DEVICE - An intravascular device can comprise a carrier and an expansion apparatus. The device can be used for intravascular treatment of atherosclerotic plaque. The carrier can be reversibly expandable and collapsible within a vessel and can have ribbon strips extending between opposite ends in a longitudinal direction of the carrier. The ribbon strips can each be formed with a plurality of elongated protrusions thereon. The expansion apparatus can be used to actuate the ribbon strips each with the plurality elongated protrusions to pierce a luminal surface of the plaque with lines or patterns of microperforations which act as serrations for forming cleavage lines or planes in the plaque.2013-06-27
20130165959ADJUSTABLE RESECTION DEVICE AND RELATED METHODS OF USE - A medical device and related method of use for resecting a tissue. The medical device may include an elongate member having a proximal end, a distal end, and a lumen extending therebetween. The elongate member may include a distal portion defining a cavity having an opening. In addition, a mechanism may be configured to adjust a volume of the cavity by altering a depth of the cavity.2013-06-27
20130165960System and Methods of Using Image-Guidance for Providing an Access to a Cochlear of a Living Subject - A system and methods for providing an access to a cochlea of a living subject. In one embodiment of the present invention, a method comprises the steps of operating a surgical instrument towards a region of interest of the living subject for opening an access to the cochlea of the living subject from the lateral edge of the skull of the living subject to the cochlea of the living subject, and intra-operatively monitoring at least a part of the surgical instrument so that the surgical instrument is operated substantially along a predetermined path.2013-06-27
20130165961LANCET CARTRIDGE - A lancet cartridge is provided with a skin contact section that is held in the interior of a lancet holder and that includes a second pricking opening. A first pricking opening is formed to a size such that a skin contact section can be accommodated therein. Upon pressing in the pricking direction, the skin contact section is accommodated in the first pricking opening, and the leading end section of a pricking member protrudes through the second pricking opening.2013-06-27
20130165962SURGICAL DEVICE, METHOD OF PERFORMING SURGERY USING SAME, AND SURGICAL DEVICE KIT - A surgical device for severing a targeted tissue structure embedded within biological tissue of a patient includes a solid needle having an elongated length and extending lengthwise between opposing first and second ends. The solid needle includes an outer surface and a needle cross-sectional dimension, A hollow needle is slidingly received along the solid needle. The hollow needle includes a needle passage having a passage cross-sectional dimension. A surgical filament is operatively connected to the solid needle and has a filament cross-sectional dimension. The passage cross-sectional dimension can be greater than the sum of the needle cross-sectional dimension and the filament cross-sectional dimension such that the solid needle and the surgical filament can co-extend through the needle passage in substantially freely sliding relation to the hollow needle. A surgical device kit and methods of use are also included.2013-06-27
20130165963Devices and Methods for Occluding or Promoting Fluid Flow - Devices and methods for occluding or promoting fluid flow through openings are disclosed. In one exemplary embodiment an occlusion device is provided having an expandable outer elongate tubular body, a guide member extending from a distal end of the outer body, and a slide tube disposed within the outer body, the proximal portions of the outer body and the slide tube being fixedly mated. The slide tube is configured to slide distally within the outer tubular body when the tubular body is expanded to form wings. A tether can be included as part of the device and it can be used to assist in positioning and locking a location of the device in an opening. Exemplary methods for delivering devices disclosed herein are also provided.2013-06-27
20130165964ACTIVE PRESSURE CONTROL FOR VASCULAR DISEASE STATES - A system includes a sensor, a controller and an actuator. The sensor is configured to provide a signal corresponding to pressure in a vascular system. The controller is configured to receive the signal and generate an output. The actuator is coupled to the controller and configured to modulate an element of the vascular system based on the pressure.2013-06-27
20130165965PRESSURE TRANSDUCER EQUIPPED CARDIAC PLUG - Disclosed herein is a pressure sensing left atrial occluding implantable medical device. The implantable medical device includes a cardiac plug and a micro electro-mechanical system (“MEMS”). The cardiac plug includes an expandable lobe and an expandable disc proximal the lobe. The expandable lobe is configured to expand into an anchoring arrangement within the left atrial appendage. The expandable lobe is configured to expand into an occluding arrangement with the left atrial appendage. The MEMS is coupled to the cardiac plug proximal of the disc. The MEMS is configured to sense surrounding fluid pressure.2013-06-27
20130165966Devices, Systems and Methods for Closure of Cardiac Openings - The invention generally relates to devices, systems, and methods for percutaneous closure of cardiac openings and obliteration of the cardiac cul-de-sacs. In one embodiment, a closure device includes a patch with an adhesive and/or a removable frame. The patch may be placed across a cardiac opening, such as a patent foramen ovale, or across a cardiac cul-de-sac, such as a left atrial appendage. In another embodiment, a closure device includes a balloon together with adhesives and/or substances for stimulating tissue growth coated on, or contained within, the balloon. The balloon may be inserted into a cardiac opening, such as the patent foramen ovale, or into a cardiac cul-de-sac, such as a left atrial appendage.2013-06-27
20130165967HEART OCCLUSION DEVICES - This disclosure is directed to an aperture occlusion device and a method for occluding an aperture, including a perimembranous ventricular septal defect. The aperture occlusion device includes a wire frame element. The wire frame forms geometric shapes that include an occluder region and a securing region. The occluder region and the securing region are separated by an attachment region including a waist. The occluder region and securing region can include membranous coverings. The device can be attached to a delivery hub. The wires forming the occluder region and securing region can have a shape-memory capability such that they can be collapsed and distorted in a sheath during delivery, but resume and maintain their intended shape after delivery.2013-06-27
20130165968APPARATUS AND METHODS FOR SEALING A VASCULAR PUNCTURE - An apparatus for sealing a puncture includes a cartridge, a pusher member, a sealant, and a tamping device on a proximal end of the cartridge. During use, the cartridge, sealant, and pusher member are advanced over a positioning member and into the puncture by advancing a cartridge hub carrying the tamping device. When further distal advancement of the cartridge is limited, the cartridge hub is further advanced, activating the tamping device, and causing the pusher member to advance relative to the sealant to compress the sealant within the puncture.2013-06-27
20130165969DEVICE FOR CONTROLLING A BLOOD FLOW PRODUCED IN A HEMORRHAGIC AREA - A device for controlling blood flow occurring in a haemorrhagic zone of a biological tissue, includes a flexible plate arranged to be placed opposite this zone, the flexible plate including: substantially leaktight peripheral supporting elements, for applying on the tissue so that the zone is surrounded; a back wall delimiting, with the supporting elements, opposite the zone, a hollow space; connecting elements connecting the hollow space, externally to the flexible plate, to an external aspiration source for creating a vacuum in the hollow space for aspirating and tightly applying the surface of the tissue against the peripheral supporting elements; and a hollow stud placed between the zone and the back wall and hollowed out in its centre on the side of the zone along an axis substantially perpendicular to the back wall, and arranged to be in contact with the zone when the vacuum is created in the space.2013-06-27
20130165970BONDING TISSUES AND CROSS-LINKING PROTEINS WTH NAPHTHALIMIDE COMPOUNDS - Naphthalimide compounds are used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together, and bond tissues and other biomaterials together. A naphthalimide-labeled biomolecule, such as a naphthalimide-labeled chitosan, is also capable of bonding tissues without subsequent direct illumination of the contacted tissue area. The naphthalimide compounds may be used in tissue or arterial repair, stabilization of an expanded arterial wall after angioplasty, tethering pharmaceutical agents to tissue surfaces to provide local drug delivery, and for chemically bonding skin care products, sunscreens, and cosmetics to the skin.2013-06-27
20130165971BARB CONFIGURATIONS FOR BARBED SUTURES - A barbed suture for connecting tissue, and a combination surgical needle with a barbed suture. The suture includes an elongated body and a plurality of barbs projecting from the body. Each barb causes the suture to resist movement in an opposite direction from which the barb faces. The disposition of the barbs on the body may be staggered, twist cut multiple spiral, overlapping, or random. Also, the configuration of the barbs may be a certain spirality angle α, barb cut angle Θ, barb cut depth, barb cut length, barb cut distance, corrugated barb underside, arcuate barb base, or varying barb size.2013-06-27
20130165972TENSIONABLE KNOTLESS ANCHOR SYSTEMS AND METHODS OF TISSUE REPAIR - Systems and methods for soft tissue to bone repairs, without knot tying. The soft tissue repair systems include self-cinching constructs with splices and loops that are pre-loaded onto modified knotless anchors (for example, swivel and/or screw-in suture anchors and/or push-in suture anchors with a distal eyelet) to position the self-locking, adjustable construct at the repair site. The systems allow for knotless tensioning of the tissue after the knotless anchors have been implanted.2013-06-27
20130165973COMPACT LINE LOCKS AND METHODS - A line lock includes a body at least partially bounding two passageways that cooperate to receive a locking portion of a line such as a suture in such a manner that the locking portion can only be drawn through the passageways along one direction. A second suture locking portion may also be received by the passageways, or by one of the two passageways in combination with a third passageway. The body may have an elongated, compact shape that is easily implantable in the body.2013-06-27
20130165974SYSTEMS AND METHODS FOR POSTERIOR DYNAMIC STABILIZATION OF THE SPINE - Devices, systems and methods for dynamically stabilizing the spine are provided. The devices include an expandable spacer having an undeployed configuration and a deployed configuration, wherein the spacer has axial and radial dimensions for positioning between the spinous processes of adjacent vertebrae. The systems include one or more spacers and a mechanical actuation means for delivering and deploying the spacer. The methods involve the implantation of one or more spacers within the interspinous space.2013-06-27