24th week of 2012 patent applcation highlights part 54 |
Patent application number | Title | Published |
20120149851 | SEPARATING AGENT FOR OPTICAL ISOMERS - To provide a novel separating agent for optical isomers based on a polymer having an optically active moiety, provided is a separating agent for optical isomers formed of: a helical polymer obtained by using an aromatic isonitrile as a monomer having an amide group in which an optically active amino acid is amide-bonded to an aromatic ring; and a carrier for carrying the helical polymer by being chemically bonded to an end of the helical polymer. | 2012-06-14 |
20120149852 | POLYIMIDE NANOWEB WITH AMIDIZED SURFACE AND METHOD FOR PREPARING - The present invention is directed to the preparation and use of aromatic polyimide nanowebs with amide-modified surfaces. Uses include as a filtration medium, and as a separator in batteries, particularly lithium-ion batteries. The invention is also directed to a filtration apparatus comprising the aromatic polyimide nanoweb with amide-modified surface. The invention is further directed to a multi-layer article comprising the aromatic polyimide nanoweb with amide-modified surface, and to an electrochemical cell comprising the multi-layer article. | 2012-06-14 |
20120149853 | NOVEL METHOD FOR PRODUCING POLYPHENYLENE ETHER - Method for producing polyphenylene ether, comprising preparing a polymerization solution of 10-25 parts by mass of a phenolic compound (M) and 75-90 parts by mass of an aromatic solvent (A) with the total of the compound and the solvent being 100 parts by mass, and 0.1-10 parts by mass of a catalyst (C) containing a metal salt; performing oxidative polymerization of the phenolic compound (M) by passing oxygen-containing gas through polymerization solution; stopping polymerization by mixing aqueous chelating agent solution into polymerization solution; subjecting a diphenoquinone compound produced as a by-product to quinone binding process or removal by reduction; and obtaining polyphenylene ether by separating aqueous phase through liquid-liquid separation. In the method for producing a polyphenylene ether, 0.001-0.004 part by weight of an ion catalyst (D) is added into the polymerization solution before the liquid-liquid separation. | 2012-06-14 |
20120149854 | NANO-LINKED HETERONUCLEAR METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS - The present invention provides polymerization catalyst compositions employing novel heterodinuclear metallocene compounds. Methods for making these new dinuclear metallocene compounds and for using such compounds in catalyst compositions for the polymerization of olefins are also provided. | 2012-06-14 |
20120149855 | Nano-Linked Metallocene Catalyst Compositions and Their Polymer Products - The present invention provides polymerization catalyst compositions employing novel dinuclear metallocene compounds. Methods for making these new dinuclear metallocene compounds and for using such compounds in catalyst compositions for the polymerization and copolymerization of olefins are also provided. | 2012-06-14 |
20120149856 | CATALYST ACTIVATION IN A DUAL REACTOR PROCESS - Catalysts are activated in a dual reactor solution process by adding substoichiometric and superstoichiometric amounts of an ionic activator to an organometallic polymerization catalyst in a first and second reactor respectively. The new activation method allows one to alter process conditions in a favorably way with minimum impact to process economics. The new activation method also provides polymers which give films having improved optical properties. | 2012-06-14 |
20120149857 | CATALYST SYSTEM AND A PROCESS FOR THE PRODUCTION OF POLYETHYKLENE - The invention relates to a catalyst system comprising I. a solid reaction product obtained by reaction of: (a) a hydrocarbon solution comprising (1) an organic oxygen containing magnesium compound (2) an organic oxygen containing titanium compound and (3) at least one compound containing zirconium and/or hafnium (b) a mixture comprising a metal compound having the formula MeR | 2012-06-14 |
20120149858 | Controlled Distribution of Active Sites in Ziegler-Natta Catalyst Systems - The present invention provides a method for improving and controlling the activity of Ziegler-Natta catalyst systems. | 2012-06-14 |
20120149859 | LATEX FOR DIP MOLDING, COMPOSITION FOR DIP MOLDING, PREPARATION METHOD OF DIP MOLDED PRODUCT, AND DIP MOLDED PRODUCT PREPARED THEREBY - Provided are a latex for dip molding, a composition for dip molding, a preparation method of a dip molded product, and a dip molded product prepared thereby. The latex for dip molding includes a conjugated diene monomer, an ethylenically unsaturated nitrile monomer, and an ethylenically unsaturated acid monomer, wherein the latex further includes sodium methallyl sulfonate as a copolymerizable ionic monomer. A dip molded product having excellent tensile strength, elongation, and touch may be obtained from a composition using the latex according to the present invention, and the generation of limitations, such as non-uniformity of physical properties and difficulties in product management, may be prevented. | 2012-06-14 |
20120149860 | FLUOROALKYL GROUP-CONTAINING N-SUBSTITUTED (METH)ACRYLAMIDE COMPOUND, POLYMER THEREOF , AND USE THEREOF - A compound represented by the following formula (a): | 2012-06-14 |
20120149861 | LACTAM-BASED COMPOUNDS WITH A URETHANE OR UREA FUNCTIONAL GROUP, AND USES THEREOF - Compounds comprising a lactam moiety, and a urethane or urea functional group are presented. By a preferred synthesis route, they are prepared using at least one polymerizable compound comprising an isocyanate moiety and reacting it with at least one hydroxyalkyl lactam compound or one aminoalkyl lactam compound. In preferred embodiments the lactam moiety is a pyrrolidone or caprolactam ring, and the polymerizable compound is a functionalized aryl isocyanate. The compounds and homopolymers and non-homopolymers thereof find useful application in a wide variety of arts, including: adhesive, agricultural, biocides, cleaning, coating, electronics, encapsulation, membrane, microelectronics, oilfield, performance chemical, personal care, sealant, and sensor applications. | 2012-06-14 |
20120149862 | PROCESS FOR PREPARING POLYESTER ALCOHOLS - The invention relates to a process for preparing polyester alcohols by catalytic reaction of at least one at least polyfunctional carboxylic acid with at least one polyfunctional alcohol and/or by catalytic ring-opening polymerization of cyclic esters in the presence of catalysts, wherein a zeolite is used as catalyst. | 2012-06-14 |
20120149863 | ISOSORBIDE - CONTAINING POLYCARBONATES AND THEIR PREPARATION - Provided herein are isosorbide-based bisphenol polymer structural units and methods of making the same. These structural units may be polymerized with one or more other types of structural units to form polymers, such as polycarbonates. | 2012-06-14 |
20120149864 | POLY(ORTHOESTER) POLYMERS, AND METHODS OF MAKING AND USING SAME - Poly(orthoester) polymers, and methods of making and using such poly(orthoester) polymers are provided. The poly(orthoester) polymers can be useful for applications including, for example, medical devices and pharmaceutical compositions. In a preferred embodiment, the poly(orthoester) polymers are biodegradable. | 2012-06-14 |
20120149865 | NOVEL METHOD FOR PRODUCING POLYPHENYLENE ETHER - Method for producing polyphenylene ether, comprising preparing a polymerization solution of 10-25 parts by mass of a phenolic compound (M) and 75-90 parts by mass of an aromatic solvent (A) with the total of the compound and the solvent being 100 parts by mass, and 0.1-10 parts by mass of a catalyst (C) containing a metal salt; performing oxidative polymerization of the phenolic compound (M) by passing oxygen-containing gas through polymerization solution; stopping polymerization by mixing aqueous chelating agent solution into polymerization solution; subjecting a diphenoquinone compound produced as a by-product to quinone binding process or removal by reduction; and obtaining polyphenylene ether by separating aqueous phase through liquid-liquid separation. In the method for producing a polyphenylene ether, 0.001-0.004 part by weight of an ion catalyst (D) is added into the polymerization solution before the liquid-liquid separation. | 2012-06-14 |
20120149866 | Solvent resistant polymers - What is disclosed relates to polymers that resist dissolution in organic solvents, are vasodilators, and are tunable explosives. These polymers also form solvent resistant coatings and solvent resistant fibers as well as bonding materials. | 2012-06-14 |
20120149867 | Method For Processing Crustaceans And Products Thereof - The present invention contemplates the creation of a low fluoride oil processed from a phospholipid-protein complex (PPC) formed immediately upon a crustacean (i.e., for example, krill) catch. The process comprises disintegrating the crustaceans into smaller particles, adding water, heating the result, adding enzyme(s) to hydrolyze the disintegrated material, deactivating the enzyme(s), removing solids from the enzymatically processed material to reduce fluoride content of the material, separating and drying the PPC material. Then, using extraction with supercritical CO | 2012-06-14 |
20120149868 | PURIFICATION OF PEPTIDES PREPARED BY SOLID PHASE SYNTHESIS - The invention relates to an effective process for purifying a peptide which has been prepared by solid phase peptide synthesis. Also encompassed by the invention is a kit comprising reagents for said process and the purified peptide obtained by said process. | 2012-06-14 |
20120149869 | ALPHA-CONOTOXIN PEPTIDES - The invention relates to relatively short peptides (termed α-conotoxins herein), about 10-30 residues in length, which are naturally available in minute amounts in the venom of the cone snails or analogous to the naturally available peptides, and which preferably include two disulfide bonds. | 2012-06-14 |
20120149870 | Sequentially arranged streptavidin-binding modules as affinity tags - The present invention relates to sequentially arranged streptavidin-binding binding modules which may in particular be used as affinity tags. The affinity tags comprise at least two individual modules capable of mediating avidic binding to streptavidin. | 2012-06-14 |
20120149871 | Synthetic, Defined Fibronectin Mimetic Peptides And Surfaces Modified With The Same - The present invention discloses compositions for applications that mimic fibronectin coated surfaces. Advantageously, such compositions provide an animal free (xeno-free, and human-component-free), synthetic, chemically defined surface that mimics at least one of the functionalities of fibronectin. | 2012-06-14 |
20120149872 | Channel-based purification device - The present invention relates to a device for purifying an analyte from a fluid sample. The device comprises a channel or tubing having an inner surface that binds to the analyte of interest in the fluid sample. As the fluid sample flows through the channel, the analyte of interest binds to the inner wall of the channel. The bound analyte is then eluted using a small bolus of elution buffer. The channel generates a high surface area for capturing the analyte in a large volume sample, but allows low liquid elution volume for concentrating the analyte into a small volume. | 2012-06-14 |
20120149873 | METHOD FOR PURIFYING ALBUMIN - An improved method for purifying albumin, a variant or fragment thereof, a fusion protein comprising albumin, a variant or fragment thereof, or a conjugate comprising albumin, a variant or fragment thereof is disclosed. | 2012-06-14 |
20120149874 | METHOD FOR PREPARING RECOMBINANT GLYCOPROTEINS WITH HIGH SIALIC ACID CONTENT - The present disclosure relates to a method for preparing recombinant glycoproteins with high sialic acid content. More specifically, for UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE/MNK) enzyme where point mutation was induced by substituting arginine at position 263 by leucine only or by further substituting arginine at position 266 by glutamine, epimerase activity is constantly maintained, and overexpressed cells thereof experience an increase in intracellular cytidine monophosphate (CMP)-sialic acid content, irrespective of CMP-sialic acid concentration. Particularly, since in an glycoprotein(such as, erythropoietin and thrombopoietin)-producing host cell where point mutationinduced GNE/MNK, human alpha-2,3-sialyltransferase and a CMP-sialic acid transporter gene are simultaneously overexpressed, intracellular content of CMP-sialic acid and sialic acid in glycoprotein increases in cells, overexpression in a host cell producing a sialylated recombinant glycoprotein the three genes above may be useful for preparing glycoprotein with increased sialic acid content. | 2012-06-14 |
20120149875 | AFFINITY CHROMATOGRAPHY MATRIX - The present invention relates to a method of separating one or more immunoglobulin containing proteins from a liquid. The method includes first contacting the liquid with a separation matrix comprising ligands immobilised to a support; allowing the immunoglobulin containing proteins to adsorb to the matrix by interaction with the ligands; followed by an optional step of washing the adsorbed immunoglobulin containing proteins; and recovering said immunoglobulin containing proteins by contacting the matrix with an eluent which releases the proteins. The method improves upon previous separation methods being that each of the ligands consists essentially of a monomer or dimer SpA or protein Z or a functional variant thereof. | 2012-06-14 |
20120149876 | Stable Heterodimeric Antibody Design with Mutations in the Fc Domain - The provided scaffolds have heavy chains that are asymmetric in the various domains (e.g. CH2 and CH3) to accomplish selectivity between the various Fc receptors involved in modulating effector function, beyond those achievable with a natural homodimeric (symmetric) Fc molecule, and increased stability and purity of the resulting variant Fc heterodimers. These novel molecules comprise complexes of heterogeneous components designed to alter the natural way antibodies behave and that find use in therapeutics. | 2012-06-14 |
20120149877 | TUMOR-SPECIFIC RECOGNITION MOLECULES - The invention relates to recognition molecules which are directed towards tumors and can be used in the diagnosis and therapy of tumor diseases. | 2012-06-14 |
20120149878 | PROTEIN PURIFICATION - Methods of reducing high molecular weight species (HMW) formation in a sample containing a protein purified using ion exchange (IEX) chromatography are disclosed, as are a number of related methods, e.g., methods of reducing on-column denaturation of a protein in a protein sample purified using an ion exchange (IEX) column or resin. The methods share characteristics of including arginine, glycine and/or histidine in the buffers used during the ion exchange (IEX) chromatography. | 2012-06-14 |
20120149879 | BISPECIFIC ANTI-EGFR/ANTI-IGF-1R ANTIBODIES - The present invention relates to bispecific antibodies against EGFR and against IGF-1R, methods for their production, pharmaceutical compositions containing said antibodies, and methods of treatment using the antibodies. | 2012-06-14 |
20120149880 | Nucleic Acid Cassette For Producing Recombinant Antibodies - The invention provides a nucleic acid cassette comprising components in the following structure: A-B-C, wherein “A” is a nucleic acid sequence encoding a light chain of a first antibody (or antigen binding domain thereof), “B” is a nucleic acid sequence encoding a 2A peptide, “C” is a nucleic acid sequence encoding a heavy chain of a second antibody (or antigen binding domain thereof), and “-” is a phosphodiester or phosphorothioate bond. Also provided is a nucleic acid cassette with the structure A-p-B-C, where “p” is a nucleic acid encoding a protease recognition site, Also provided are methods for making recombinant antibodies using the nucleic acid cassette of the invention, cells and vector comprising the nucleic acid cassette of the invention, and kits for making the nucleic acid cassette of the invention. | 2012-06-14 |
20120149881 | APOPTOTIC ANTI-IGE ANTIBODIES - The present application relates to apoptotic anti-IgE antibodies, nucleic acid encoding the same, therapeutic compositions thereof, and their use in the treatment of IgE-mediated disorders. | 2012-06-14 |
20120149882 | YKL-40 MONOCLONAL ANTIBODY - The present invention relates to monoclonal anti-human YKL-antibodies which are capable to modulate biological processes in which YKL-40 plays a prominent role, e.g. inhibit the growth and/or inducing apoptosis of cells, in particular cancer cells. The invention also relates to pharmaceutical compositions comprising said antibodies and uses said antibodies and/or pharmaceutical compositions for treatment of a disease wherein inhibition of cell growth, cell differentiation, remodelling of extracellular matrix, metastasis and/or induction of cell death due to apoptosis is a prerequisite for successful curing. An antibody of the invention is capable of inhibiting biological function of YKL-40 in the above mentioned processes by binding to a specific epitope on YKL-40. | 2012-06-14 |
20120149883 | Detection and quantification of modified proteins - The invention provides a method detecting and quantifying proteins by mass spectrophotometric analysis using peptide internal standards and provides a highly sensitive way of detecting protein modifications. In one aspect, the invention provides a method for determining a site of ubiquitination in a polypeptide and for evaluating ubiquitination targets in a population of polypeptides. In this way, a proteome ubiquitination map can be obtained which comprises information relating to the ubiquitination states of a plurality of cellular polypeptides. Maps can be obtained for a variety of different types of cells and cell states. For example, ubiquitination targets in normal and diseased cells can be evaluated. Preferably, the map is stored as data files in a database. Individual ubiquitinated polypeptides identified can be used to generate molecular probes diagnostic of a cell state and/or can serve as targets for agents that modulate one or more cellular processes. | 2012-06-14 |
20120149884 | SPECIFIC ANTIBODY SELECTION BY SELECTIVE ELUTION CONDITIONS - Methods for preparing high avidity anti-antigen polyclonal antibody preparations by antigen affinity column purification and high avidity anti-antigen polyclonal antibody preparations are described. | 2012-06-14 |
20120149885 | DOWNSTREAM BIOPROCESSING DEVICE - Large-scale downstream processing of secreted recombinant proteins is provided in a single device, wherein the contents of a plurality of bioreactors are combined simultaneous to their harvesting and purification resulting in significant savings of time and the cost of manufacturing. | 2012-06-14 |
20120149886 | PRODUCTION OF CAROTENOIDS IN OLEAGINOUS YEAST AND FUNGI - The present disclosure provides systems for producing engineered oleaginous yeast or fungi that express carotenoids. | 2012-06-14 |
20120149887 | ALKYNYL SUGAR ANALOGS FOR LABELING AND VISUALIZATION OF GLYCOCONJUGATES IN CELLS - Methods for metabolic oligosaccharide engineering that incorporates derivatized alkyne-bearing sugar analogs as “tags” into cellular glycoconjugates are disclosed. Alkynyl derivatized Fuc and alkynyl derivatized ManNAc sugars are incorporated into cellular glycoconjugates. Chemical probes comprising an azide group and a visual or fluorogenic probe and used to label alkyne-derivatized sugar-tagged glycoconjugates are disclosed. Chemical probes bind covalently to the alkynyl group by Cu(I)-catalyzed [3+2] azide-alkyne cycloaddition and are visualized at the cell surface, intracellularly, or in a cellular extract. The labeled glycoconjugate is capable of detection by flow cytometry, SDS-PAGE, Western blot, ELISA, confocal microscopy, and mass spectrometry. | 2012-06-14 |
20120149888 | SYNTHESIS OF ARA-2'-O-METHYL-NUCLEOSIDES, CORRESPONDING PHOSPHORAMIDITES AND OLIGONUCLEOTIDES INCORPORATING NOVEL MODIFICATIONS FOR BIOLOGICAL APPLICATION IN THERAPEUCTICS, DIAGNOSTICS, G- TETRAD FORMING OLIGONUCLEOTIDES AND APTAMERS - The present invention relates to synthesis, purification and methods to obtain high purity novel 2′-arabino-O-methyl nucleosides and the corresponding phosphoramidites of various arabinonucleoside bases and introduction of such units into defined sequence synthetic DNA and RNA. Various synthetic oligonucleotides, such as HIV integrase inhibitor 14-mer and thrombin binding oligonucleotide, thrombin-1, bearing ara-2′-omethyl modification have been synthesized. It is anticipated the oligonucleotides incorporating these monomers will exhibit biological activities related to antisense approach approach, design of better SiRNA's, diagnostic agents. Similarly, it is anticipated that oligonucleotides incorporating such novel nucleosides will be useful to develop therapeutic candidates designing stable G-quadruplexes and Aptamers for oligonucleotide structure, folding topology, evaluation of biochemical properties and design and develop as therapeutic agents. It is further anticipated that the nucleosides, phosphates and triphosphates of this invention could develop as therapeutic agents. | 2012-06-14 |
20120149889 | Methods and compositions of DNA ligands for arthropod-borne pathogen detectionand prophylaxis or therapy - Specific DNA ligand sequences for binding various arthropod-borne pathogens including arboviruses, rickettsia and parasites are described. Each of these sequences or their linear, two- and three-dimesional linked sequences can function in varying assay and sensor formats with varying degrees of success. Linkage of the whole or partial DNA sequences (putative binding sites) can be used to enhance specificity and affinity towards complex targets, thereby improving assay selectivity and sensitivity in many instances. In addition, the DNA sequences may bind and neutralize or prevent infection from arthropod-borne viruses, rickettsia and Leishmania or other parasites. | 2012-06-14 |
20120149890 | Polynucleotides Encoding Thymidine Kinase Mutants - The present invention provides isolated nucleic acid molecules encoding a Herpesviridae thymidine kinase enzyme comprising one or more mutations, at least one of the mutations encoding an amino acid substitution located toward the N-terminus from a DRH nucleoside binding site which increases a biological activity of the thymidine kinase, as compared to unmutated thymidine kinase. Such mutations include amino acid substitutions within a Q substrate binding domain which increases a biological activity of the thymidine kinase, as compared to unmutated thymidine kinase. Within a further aspect, fusion proteins are provided which have both guanylate kinase and thymidine kinase biological properties. Also provided are vectors suitable for expressing such DNA molecules, as well as methods for utilizing such vectors. | 2012-06-14 |
20120149891 | BRASSICA INDEHISCENT1 SEQUENCES - The present application provides | 2012-06-14 |
20120149892 | Nucleic Acid Molecules Encoding Antibodies That Bind Cell-Associated CA 125/O772P - The present invention provides antibodies, and antigen-binding fragments of antibodies, fusion polypeptides and analogs that preferentially bind cell-associated CA 125/O772P polypeptides relative to shed CA 125/O772P polypeptides. The present invention further provides methods of preventing, managing, treating or ameliorating one or more symptoms associated with a CA 125/O772P-related disorder. In particular, the present invention provides methods of preventing, managing, treating, or ameliorating one or more symptoms associated with a cell proliferative disorder, such as cancer, e.g., ovarian cancer. The present invention still further provides methods for diagnosing a CA 125/O772P-related disorder or predisposition to developing such a disorder, as well as methods for identifying antibodies, and antigen-binding fragments of antibodies, that preferentially bind cell-associated CA 125/O772P polypeptides relative to shed CA 125/O772P polypeptides. | 2012-06-14 |
20120149893 | MODULATION OF EIF4E-BP2 - Compounds, compositions and methods are provided for modulating the expression of eIF4E-BP2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding eIF4E-BP2. Methods of using these compounds for modulation of eIF4E-BP2 expression and for diagnosis and treatment of diseases and conditions associated with expression of eIF4E-BP2 are provided. | 2012-06-14 |
20120149894 | NOVEL CATIONIC LIPIDS WITH VARIOUS HEAD GROUPS FOR OLIGONUCLEOTIDE DELIVERY - The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with siRNA, to facilitate the cellular uptake and endosomal escape, and to knockdown target mRNA both in vitro and in vivo. | 2012-06-14 |
20120149895 | PROCESS FOR DIMETHYLATION OF ACTIVE METHYLENE GROUPS - The present invention discloses a process for dimethylation of active methylene groups. Specifically, the invention discloses a process for preparing 3-amino-2,2-dimethylpropanamide. Compounds produced by the present dimethylation process such as 3-amino-2,2-dimethylpropanamide can be used as intermediates in the route of synthesis of therapeutic, prophylactic or diagnostic agent, for example aliskiren or cryptophycin. Particularly, the invention relates to embodiments further extending to processes for preparing pharmaceutical dosage form comprising said therapeutic, prophylactic or diagnostic agents. More specifically, the invention relates to the use of compounds produced by the present dimethylation process for the manufacture of therapeutic, prophylactic or diagnostic agents or for the manufacture of pharmaceutical dosage forms comprising said therapeutic, prophylactic or diagnostic agents. The processes according to the present invention can be beneficially applied for the synthesis of various active pharmaceutical ingredients, such as aliskiren or crypthophycin. | 2012-06-14 |
20120149896 | METHOD FOR SEPARATION OF HMX AND RDX - The present invention is directed to a method for effectively separating HMX and RDX from HMX/RDX-included explosives, respectively, without using a harmful organic solvent, the method capable of respectively separating HMX and RDX from HMX/RDX-included explosives by selectively dissolving RDX included in explosives by using a difference between solubility parameters of HMX and RDX with respect to compressed dimethylether. The present invention is further directed to an apparatus for respectively separating HMX and RDX from HMX/RDX-included explosives comprising a dimethylether supplying unit, an explosive particle dissolving unit, and an explosive particle collecting unit. | 2012-06-14 |
20120149897 | METHOD OF PREPARING NITROGEN-DOPED GRAPHENE AND NITROGEN-DOPED GRAPHENE PREPARED THEREBY - The present invention relates to a method of preparing a nitrogen-doped graphene comprising preparing a Edge-Functionalized Graphene by binding a graphite with a organic material having amino groups and functional groups such as carboxy acid group through an electrophilic substitution reaction, and heat treating the resultant Edge-Functionalized Graphene, and a nitrogen-doped graphene prepared thereby. According to the present invention, by a more inexpensive and simpler method, a nitrogen-doped graphene can be prepared at higher purity and higher yield. The nitrogen-doped graphene obtained by the present invention has very excellent physical and electric properties, and particularly has a superior oxygen reduction capability, compared with the platinum catalyst used at cathode of a H | 2012-06-14 |
20120149898 | DIHYDRODIAZEPINES USEFUL AS INHIBITORS OF PROTEIN KINASES - The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. | 2012-06-14 |
20120149899 | PROCESS FOR PRODUCING BENZO[B][1,4]DIAZEPINE-2,4-DIONE COMPOUND - The present invention provides an industrially advantageous, simple, and efficient process for producing a key intermediate of a benzo[b][1,4]diazepine-2,4-dione compound, which is a therapeutic medicine for arrhythmia. | 2012-06-14 |
20120149900 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF - Fluorinated compounds and methods of making fluorinated compounds are described herein. | 2012-06-14 |
20120149901 | HYDROSILYLATION METHOD, METHOD FOR PRODUCING ORGANOSILICON COMPOUND, AND ORGANOSILICON COMPOUND - A hydrosilylation method is provided. In this hydrosilylation method, silylation of the carbon atom other than the terminal carbon atom and generation of the by-product isomer by internal migration of the double bond are suppressed without sacrificing the hydrosilylation reactivity, even if an olefin compound having tertiary amine atom which can be a catalyst poison was used. In the hydrosilylation, an olefin compound having carbon-carbon unsaturated bond, and a compound having hydrogensilyl group are reacted in the presence of an acid amide compound, a nitrile compound and an aromatic hydroxyl compound, or an organoamine salt compound, by using catalytic action of platinum and/or its complex compound. | 2012-06-14 |
20120149902 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVE - Provided is a compound represented by the Formula (I) having a HER2 inhibitory action or a pharmacologically acceptable salt thereof, | 2012-06-14 |
20120149903 | PROCESS FOR PREPARING AND PURIFYING 3-AMINOPROPANOL - The present invention relates to a process for purifying a reaction output which comprises 3-aminopropanol and is obtained in the reaction of ethylene cyanohydrin with hydrogen in the presence of ammonia, which comprises distilling the reaction output comprising 3-aminopropanol in two or more stages, the ammonia content of the reaction output comprising 3-aminopropanol before introduction into the first distillation stage being 1% by weight or less and the temperature in the distillation stages being not more than 135° C. | 2012-06-14 |
20120149904 | BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS - The present invention relates to compounds of formula | 2012-06-14 |
20120149905 | PROCESS FOR THE MANUFACTURE OF ROSUVASTATIN CALCIUM USING CRYSTALLINE ROSUVASTATIN ETHYL ESTER - The present invention relates to an improved process to prepare Rosuvastatin calcium of Formula (I), with good quality. Further, the present invention also relates to a crystalline polymorphic form of Rosuvastatin ethyl ester. | 2012-06-14 |
20120149906 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS - Chiral ruthenium catalysts comprising salen and alkenyl ligands are provided for stereoselective cyclopropanation, and methods of cyclopropanation are provided. The chiral ruthenium catalyst is prepared in situ by combining an alkenyl ligand, a deprotonated chiral salen ligand, and a ruthenium (II) metal. A preferred catalyst is prepared in situ by combining 2,3-dihydro-4-venylbenzofuran, deprotonated 1,2-cyclohexanediamino-N,N′-bis(3,5-di-t-butyl-salicylidene) and RuCl | 2012-06-14 |
20120149907 | PROCESS FOR PREPARING TRICHLOROAMMINEPLATINATE SALT AND THE PRODUCTS OBTAINED THEREIN - The present invention relates to a process for preparing a trichloroammineplatinate salt by reacting a tetrachloroplatinate salt in aqueous solution in the presence of ammonium chloride and an alkali chloride with one or more carbonate salts selected from the group consisting of potassium, sodium and ammonium carbonate while keeping the pH value below 7 during the reaction; the product obtained therein and a use thereof. | 2012-06-14 |
20120149908 | TRIAZOLYLPIPERIDINE DERIVATIVES AND METHOD FOR MAKING THE SAME - In a first aspect, the present invention relates to a method for the preparation of alkynylpiperidine and alkynylpiperidine derivatives. In particular, a method is provided for preparing alkynylpiperidine derivatives starting from epoxide compounds. Further, the alkynylpiperidine derivatives according to the present inventions are substituted trans-3-4-alkynylpiperidine derivatives. In another aspect, triazolylpiperidine compounds and methods for said preparation are provided. In particular, the triazolylpiperidine compounds according to the present invention are obtained by reacting an alkynylpiperidine derivatives with an organic azid, preferably, in the presence of a Cu (I) or Ru catalyst. In a preferred embodiment, 1,4-disubstituted or 1,5-disubstituted 1,2,3-triazolylpiperidine compounds are provided. | 2012-06-14 |
20120149909 | N-SUBSTITUTED-N-PHENYLETHYLSULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY - Novel compounds are continually sought after to treat and prevent diseases and disorders. The invention relates to N-substituted-N-phenylethylsulfonamides useful for being biologically and pharmacologically screened, and to contribute to the exploration and identification of new lead molecules that are capable of modulating the functional activity of a biological target. | 2012-06-14 |
20120149910 | Pesticidal Carboxamides - The object of the present invention is to provide novel carboxamides which exhibit an excellent pesticidal activity as pesticides. Disclosed are the carboxamides represented by the following Formula (I): | 2012-06-14 |
20120149911 | DERIVATIVE N-THIOLATED 2-OXAZOLIDINONE ANTIBIOTICS - This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against | 2012-06-14 |
20120149912 | PROCESS FOR THE PREPARATION OF 1-BENZYL-3-HYDROXYMETHYL-1H-INDAZOLE AND ITS DERIVATIVES AND REQUIRED MAGNESIUM INTERMEDIATES - The present invention relates to the process for the conversion of 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (II), to the 1-benzyl-3-hydroxylmethyl-1H-indazole according to formula (I). | 2012-06-14 |
20120149913 | SILANOL-CONTAINING TRIARYLAMINE DERIVATIVES - Provided are triarylamine derivatives excellent in compatibility with various organic solvents or resins, capable of forming a silicon-oxygen bond on the surface of an inorganic material, and allowing easy purification; a preparation process of the triarylamine derivative; an intermediate product of the triarylamine derivative; an inorganic composite material obtained by bonding the triarylamine derivative to the surface of an inorganic material; and a preparation process of the inorganic composite material. | 2012-06-14 |
20120149914 | Method for Synthesizing Substituted Aminocyclohexanone Compounds - A method of synthesizing a substituted aminocyclohexanone compound comprising reacting a compound of formula (II) | 2012-06-14 |
20120149915 | METHOD FOR SYNTHESIS OF N-ALKYL CARBAZOLE AND DERIRATIVES THEREOF - Disclosed is a process for the preparation of N-alkyl carbazole. Said process comprises: a) chlorinating cyclohexanone to form 2-chlorocyclohexanone; b) reacting 2-chlorocyclohexanone with N-ethyl aniline to form 2-(N-ethyl anilino) cyclohexanone; c) cyclizing 2-(N-ethyl anilino) cyclohexanone by refluxing with simultaneous water removal to obtain 9-ethyltetrahydrocarbazole; d) treating 9-ethyl-tetrahydrocarbazole with concentrated hydrochloric acid followed by water wash for removing N-ethyl aniline; e) dehydrogenating 9-ethyltetrahydrocarbazole by heating 9-ethyltetrahydrocarbazole in a solvent, in presence of a catalyst to obtain N-alkyl carbazole. | 2012-06-14 |
20120149916 | NOVEL COMPOUND - A compound represented by general formula (c1) (R | 2012-06-14 |
20120149917 | (E)-N-MONOALKYL-3-OXO-3-(2-THIENYL) PROPENAMINE AND PROCESS FOR PRODUCING THE SAME AND PROCESS FOR PRODUCING (E,Z)-N-MONOALKYL-3-OXO-3-(2-THIENYL) PROPENAMINE - The present invention provides a process for producing (E)-N-monoalkyl-3-oxo-3-(2-thienyl)propenamine represented by Formula (1); | 2012-06-14 |
20120149918 | PROCESS FOR THE MANUFACTURE OF 3-DIBUTYLAMINO-6-METHYL-7-ANILINOFLUORAN - A process for the preparation of 3-dibutylamino-6-methyl-7-anilinofluoran and a heating- and pressure sensitive recording material are claimed. | 2012-06-14 |
20120149919 | MALEIC ANHYDRIDE SYNTHESIS CATALYST PRECURSOR AND PROCESS FOR ITS PREPARATION - A process for preparing a vanadium, phosphorus, and oxygen comprising catalyst precursor for preparing maleic anhydride by heterogeneously catalyzed gas-phase oxidation of a hydrocarbon having at least four carbon atoms, which comprises
| 2012-06-14 |
20120149920 | Method for the production of a mixture of lactide derivatives - A mixture of cyclic diesters derived from lactic acid and in cases a mixture of a racemate of dilactide may be produced in several different processes. In some instances, the process can thereby start from the corresponding alpha-hydroxycarboxylic acids, the corresponding cyclic diesters or oligomers of the corresponding alpha-hydroxycarboxylic acids. | 2012-06-14 |
20120149921 | TERTIARY ALCOHOL DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION - A polymer compound for a photoresist composition (a) having a high dissolution rate in a developing solution after exposure and (b) exhibiting little swelling during development. A tertiary alcohol derivative that is a raw material for the polymer compound. A tertiary alcohol that is an intermediate of the tertiary alcohol derivative. The tertiary alcohol is represented by formula (3): | 2012-06-14 |
20120149922 | CATALYTIC CONVERSION OF CELLULOSE TO LIQUID HYDROCARBON FUELS BY PROGRESSIVE REMOVAL OF OXYGEN TO FACILITATE SEPARATION PROCESSES AND ACHIEVE HIGH SELECTIVITIES - Described is a method to make liquid chemicals. The method includes deconstructing cellulose to yield a product mixture comprising levulinic acid and formic acid, converting the levulinic acid to γ-valerolactone, and converting the γ-valerolactone to pentanoic acid. Alternatively, the γ-valerolactone can be converted to a mixture of n-butenes. The pentanoic acid can be decarboxylated yield 1-butene or ketonized to yield 5-nonanone. The 5-nonanone can be hydrodeoxygenated to yield nonane, or 5-nonanone can be reduced to yield 5-nonanol. The 5-nonanol can be dehydrated to yield nonene, which can be dimerized to yield a mixture of C | 2012-06-14 |
20120149923 | BISPHENOL POLYMER STRUCTURAL UNITS AND METHOD OF MAKING THE SAME - Provided herein are isosorbide-based bisphenol polymer structural units and methods of making the same. These structural units may be polymerized with one or more other types of structural units to form polymers, such as polycarbonates. | 2012-06-14 |
20120149924 | PROCESS FOR THE PRODUCTION OF FURFURAL FROM PENTOSES AND/OR WATER SOLUBLE PENTOSANS - The invention is directed to a process for production of furfural from pentoses and/or water-soluble pentosans, said process comprising converting said pentoses and/or water soluble pentosans in aqueous solution in a first step to furfural and in a second step feeding the aqueous solution containing furfural obtained in step one to the top of a distillation column to produce an aqueous, liquid downflow, which column is heated at the bottom part thereof, using at least one reboiler to produce an upflow steam flow, recovering a water and furfural containing vapor product stream from the top of said column, compressing said vapor flow and condensing it on the hot side of the reboiler at the bottom of said column to produce sufficient steam in said bottom part of the column to produce said upflow steam flow, and to recover an aqueous furfural containing solution as the condensate in the reboiler. | 2012-06-14 |
20120149925 | PROCESS FOR PREPARING TAXOIDS FROM BACCATIN DERIVATIVES USING LEWIS ACID CATALYST - The present invention relates to a process of preparing a taxoid (X) by reacting a protected baccatin derivative (B) with a β-lactam (C) in the presence of one or more Lewis acids and a base agent. The present invention also relates to a process of preparing the protected baccatin derivative (B) from a baccatin derivative (A) comprising a protection reaction catalyzed by one or more Lewis acids with an optional base agent. | 2012-06-14 |
20120149926 | PROCESS FOR IMPROVING THE SELECTIVITY OF AN EO CATALYST - The present invention relates to a process for improving the overall selectivity of an EO process for converting ethylene to ethylene oxide utilizing a highly selective EO silver catalyst containing a rhenium promoter wherein following normal operation a chloride strip of the chloride on the surface of the catalyst is conducted in order to remove a portion of the chlorides on the surface of the catalyst. The chloride strip involves the addition of certain saturated hydrocarbons to the feed. Following the chloride strip, the catalyst is optionally re-optimized. | 2012-06-14 |
20120149927 | Method for treating pyropheophytin-containing compositions - The present invention provides methods and uses for treating pyropheophytin-containing compositions, particularly in order to remove pyropheophytin therefrom. The compositions are typically plant, algal, or bacterial derived products such as vegetable oils. The method comprises a step of contacting the compositions with an enzyme having pyropheophytinase activity. Also provided are related apparatus and products for performing such methods and uses. | 2012-06-14 |
20120149928 | CANOLA OIL FROM HYBRID BRASSICA VARIETIES - Canola oils from hybrid | 2012-06-14 |
20120149929 | PROCESS FOR PRODUCING SILANE COUPLING AGENT - Provided is a process for producing a silane coupling agent, which can shorten the time required for the production process. A process for producing a silane coupling agent, characterized by comprising a step of reacting a silane compound (A) with a compound (B) which has a hydroxyl group and further contains an atom having an unshared electron pair other than an oxygen atom derived from the hydroxyl group, in the presence of a metal-containing catalyst (m) to obtain a silane compound (C) which has an alkoxyl group containing the atom having the unshared electron pair other than the oxygen atom derived from the hydroxyl group. | 2012-06-14 |
20120149930 | HAIR CARE COSMETIC - Disclosed herein is a hair care cosmetic which contains an organopolysiloxane defined in following (i) or (ii):
| 2012-06-14 |
20120149931 | Use of hydrophilic-rich alkylmethylsiloxane-dimethylsiloxane-polyoxyalkylene copolymers as emulsifiers for the preparation of cosmetic o/w emulsions of improved aesthetic properties and mildness - This invention relates to the use of hydrophilic-rich, rake-type alkylmethylsiloxane-dimethylsiloxane-polyoxyalkylene copolymers. | 2012-06-14 |
20120149932 | PHOSPHORUS-CONTAINING COMPOUNDS USEFUL FOR MAKING HALOGEN-FREE, IGNITION-RESISTANT POLYMERS - Phosphorus-containing compounds useful for flame retardant epoxy resins are disclosed. The flame retardant epoxy resins may be used to make electrical laminates. This invention is particularly useful in end use applications in which a low bromine or low halogen content is required or desired. | 2012-06-14 |
20120149933 | AMMOXIDATION CATALYST AND METHOD FOR PRODUCING NITRILE COMPOUND USING THE SAME - The present invention provides an ammoxidation catalyst containing vanadium oxide, titanium oxide and diamond. | 2012-06-14 |
20120149934 | PHOTO-CROSSLINKER - Described herein is a linking agent that includes a polymeric or non-polymeric core molecule and one or more photoreactive groups covalently attached to the core molecule by one or more linking elements that include a urea linkage, a carbamate linkage, or a combination thereof. | 2012-06-14 |
20120149935 | Plasticiser Alcohol And Production Improvement - Embodiments of the invention disclosed herein relate to a process for the production of a C | 2012-06-14 |
20120149936 | METHOD FOR PRODUCING A CRYSTALLINE SOLID FROM GLYCINE-N,N-DIACETIC ACID DERIVATIVES WITH SUFFICIENTLY REDUCED HYGROSCOPICITY - The present invention relates to a process for preparing a crystalline solid from glycine-N,N-diacetic acid derivatives (e.g., MGDA) of sufficiently low hygroscopicity, which is characterized in that at least one crystalline compound of the formula I is introduced as seed, and a spray granulation is carried out with at least one compound of the formula I, preferably followed by a heat treatment. | 2012-06-14 |
20120149937 | METHOD FOR PRODUCING HYDROXYCARBOXYLIC ACID DERIVATIVE - To provide a method for the production of a hydroxycarboxylic acid derivative, by which a hydroxycarboxylic acid derivative, which can be reused in various applications, can be obtained from a polyamide at a high yield without consuming a large amount of energy. A method for the production of a hydroxycarboxylic acid derivative, which is characterized by including allowing an alcohol in a supercritical state to act on a polyamide in the presence of a carboxylic acid derivative to depolymerize the polyamide to obtain the hydroxycarboxylic acid derivative. | 2012-06-14 |
20120149938 | Processes For The Preparation Of 2,5-Dihydroxybenzenesulfonic Acid Salts - Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5 2,5-dihydroxybenzenesulfonic acid are provided. | 2012-06-14 |
20120149939 | Recovery of Acetic Acid from Heavy Ends in Vinyl Acetate Synthesis Process - Recovery of acid, and in particular acetic acid, in a vinyl acetate production process. Vinyl acetate production produces heavy ends that comprise acetate containing compounds, such as monomers and polymers. Acid preferably is recovered by hydrolyzing the heavy ends and separating the resulting hydrolyzed stream to recover acid formed from the from acetate containing compounds. | 2012-06-14 |
20120149940 | Integrin Modulators and Methods for Their Use - 1,5-Dithiaocta-2,7-diene-5-oxide-1-yl (DODOyl) compounds and derivatives thereof, referred to collectively as DODOyl-derived compounds (DDCs), and chiral enantiomers and derivatives thereof, are described, which are integrin modulators that modulate integrin-mediated functions and/or processes. Pharmaceutical compositions containing integrin modulators and chiral enantiomers thereof, and methods for using integrin modulators and chiral enantiomers thereof are further described. | 2012-06-14 |
20120149941 | Oxidation of Hydrocarbons - In a process for oxidizing a hydrocarbon to a corresponding hydroperoxide, alcohol, ketone, carboxylic acid or dicarboxylic acid, the hydrocarbon is contacted with an oxygen-containing gas in the presence of a catalyst comprising a cyclic imide of the general formula (I): | 2012-06-14 |
20120149942 | METHOD FOR HANDLING AQUEOUS SOLUTION CONTAINING WATER-SOLUBLE SUBSTANCE, METHOD FOR MANUFACTURING ALKYLBENZENE HYDROPEROXIDE, AND METHOD FOR MANUFACTURING HYDROXYBENZENE - There is provided a method for handling an aqueous solution containing a water-soluble substance that changes into a water-insoluble substance over time, including a step of bringing the aqueous solution to be treated containing the water-soluble substance that changes into the water-insoluble substance over time into contact with a water-insoluble organic solvent, and extracting the water-soluble substance into the water-insoluble organic solvent. Preferably, the water-soluble substance is alkylbenzene hydroperoxide, and the water-insoluble substance is alkylbenzene hydroperoxide-derived alcohol. Preferably, the aqueous solution to be treated is an alkaline aqueous phase separated in a water-washing step in a process of manufacturing the alkylbenzene hydroperoxide that has an alkali extraction step, the water-washing step, an oxidation step, and a reaction solution separation step. | 2012-06-14 |
20120149943 | PROCESS FOR THE PREPARATION OF RING COMPOUNDS - In a process for the preparation of ring compounds via a combinatorial synthesis, the reaction procedure is based on a Suzuki coupling; subsequent halo-demetallation and finally a further Suzuki coupling. The Suzuki couplings are each carried out with a boronic acid or a boronic acid ester. The reaction procedure uses provides novel ring compounds and uses novel synthesis units used for this purpose. The novel ring compounds are suitable for use as constituents in liquid-crystalline mixtures. | 2012-06-14 |
20120149944 | FLUID-SPARGED HELICAL CHANNEL REACTOR AND ASSOCIATED METHODS - A method of reacting compounds can include directing a liquid into a helical constrained flow ( | 2012-06-14 |
20120149945 | SKEWED AND MIDDLE ATTACHED LINEAR CHAIN ALKYLPHENOL AND METHOD OF MAKING THE SAME - A process for preparing an alkylated hydroxyl aromatic compound comprising reacting | 2012-06-14 |
20120149946 | PROCESS FOR THE PREPARATION OF 2,2,4,4-TETRAALKYLCYCLOBUTANE-1,3-DIOLS - Disclosed is a process for the preparation of a 2,2,4,4-tetraalkylcyclobutane-1,3-diols by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione in the presence of a catalyst comprising ruthenium deposited on a carbon nanotube support. The process is useful for the preparation of 2,2,4,4-tetramethylcyclobutane-1,3-diol. The process may be carried out in the presence or absence of a solvent and in the liquid or vapor phase. Also disclosed is a process for modifying the cis:trans ratio of the 2,2,4,4-tetramethylcyclo-butane-1,3-diol hydrogenation product by contacting the diol with hydrogen in the presence of a supported ruthenium catalyst. | 2012-06-14 |
20120149947 | PROCESS FOR THE PREPARATION OF 2,2,4,4-TETRAALKYLCYCLOBUTANE-1,3-DIOLS - Disclosed is a process for the preparation of a 2,2,4,4-tetraalkylcyclobutane-1,3-diol by hydrogenation of the corresponding 2,2,4,4-tetraalkylcyclobutane-1,3-dione in the vapor phase in the presence of a supported catalyst. The process is useful for the preparation of 2,2,4,4-tetramethylcyclobutane-1,3-diol from 2,2,4,4-tetramethylcyclobutane-1,3-dione. The process can produce a 2,2,4,4-tetraalkylcyclobutane-1,3-diol product having a cis:trans isomer ratio of 1:1 or greater. | 2012-06-14 |
20120149948 | PROCESS FOR THE ISOMERIZATION OF 2,2,4,4-TETRAALKYLCYCLOBUTANE-1,3-DIOLS - Disclosed is a process for the isomerization of 2,2,4,4-tetraalkylcyclobutane-1,3-diols, such as 2,2,4,4-tetramethylcyclobutane-1,3-diol, by contacting the diol with a supported ruthenium catalyst in the presence of hydrogen at elevated pressures and temperatures. The process is carried under conditions in which there is no net production of 2,2,4,4-tetraalkylcyclobutane-1,3-diol. The process may be carried out in the presence or absence of a solvent and in the liquid or vapor phase. | 2012-06-14 |
20120149949 | PROCESS FOR PRODUCING ETHANOL USING A STACKED BED REACTOR - The present invention produces ethanol in a stacked bed reactor that comprises a first catalyst comprising platinum and tin and a second catalyst comprising copper or an oxide thereof. The crude ethanol product may be separated and ethanol recovered. | 2012-06-14 |
20120149950 | PLANT FOR THE HOMOGENEOUS OXIDATION OF METHANE-CONTAINING GAS AND PROCESS FOR THE OXIDATION OF METHANE-CONTAINING GAS - The invention relates to the process for homogenous oxidation of methane-containing gas comprising feeding of methane-containing gas preheated to 430-450° C. to at least three sequentially installed oxidation reactors, wherein each reactor, with the exception of the last one, is independently connected to waste-heat boilers, the reactors are fed with oxygen for oxidation of methane-containing gas, wherein the gas mixture temperature is increased to 540-560° C. with subsequent rapid quenching-cooling of the gas mixture to 440-450° C. in waste-heat boilers where steam is formed which is fed to a rectification tower for separation of end products, from the last reactor the reaction mixture is fed to a separator, from the separator the liquid phase is fed to the rectification stage where rectified methanol, ethanol and formaldehyde are produced, and the gas phase is fed for cleaning it of SO2, CO and CO2, and in the process, partial purging of the circulation cycle is performed to remove inert gases, and after cleaning and purging the cycle is completed by replenishing the gas-phase/cycled gas with the original methane-containing gas and re-feeding, the resulting gas to the reactor. The invention makes it possible to increase efficiency, increase product yield and improve the environmental situation. | 2012-06-14 |