23rd week of 2010 patent applcation highlights part 68 |
Patent application number | Title | Published |
20100144537 | SMES SYSTEM, INTERFACE DEVICE FOR SMES AND DRIVING METHOD THEREOF - A loss can be reduced upon a current holding operation of a SMES. A superconducting magnetic energy storage (SMES) system includes a loop composed of a superconducting coil, a thyristor, and a synchronous rectification circuit, and a loop current flow through the loop. In a loop current hold mode, a switching control device of the synchronous rectification circuit turns on the thyristor, and the synchronous rectification circuit compensates for the loop current by rectifying an AC current from an AC power source to generate a DC current. | 2010-06-10 |
20100144585 | FABRIC SOFTENING COMPOSITIONS COMPRISING SILICONE COMPRISING COMPOUNDS - The present invention relates to a fabric softening composition which maintains physical stability upon freeze-thaw. | 2010-06-10 |
20100144588 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS - Novel iminium-type coupling agents containing proton acceptors in their iminium moiety, which can be used beneficially as coupling agents in various chemical polypeptide and/or polynucleotide syntheses, and are particularly useful as yield enhancing and racemization suppressing coupling agents for use in peptide syntheses, are disclosed. Further disclosed are a process of preparing such iminium-type coupling agents and their use in the preparation of polypeptides and/or polynucleotides. | 2010-06-10 |
20100144589 | METHODS OF PREDICTING CANCER LETHALITY USING REPLIKIN COUNTS - The present invention provides methods of predicting the relative growth rate, replication rate, or lethality of a first malignancy as compared to another malignancy or as compared to a plurality of malignancies, including methods of predicting the relative growth rate, replication rate, or relative lethality of a primary malignancy as compared to a metastatic malignancy, including comparing the concentration of Replikin sequences in the first malignancy with the concentration of Replikin sequences in another malignancy or malignancies and further provides Replikin peptides and Replikin Peak Genes identified within a malignancy for diagnostic, therapeutic, preventive, and predictive purposes. | 2010-06-10 |
20100144606 | COMBINATION 408 - The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is N-Cyclohexyl-N | 2010-06-10 |
20100144608 | Macrocyclic hepatitis C serine protease inhibitors - The present invention relates to novel macrocyclic compounds and methods of treating a hepatitis C infection in a subject in need of such therapy with said macrocyclic compounds. The present invention further relates to pharmaceutical compositions comprising the compounds of the present invention, or pharmaceutically acceptable salts, esters, or prodrugs thereof, in combination with a pharmaceutically acceptable carrier or excipient. | 2010-06-10 |
20100144609 | METHODS USING CYCLOSPORIN IN TREATING PATIENTS WITH INTRAOCULAR LENSES - Methods of treating a patient are disclosed in which a cyclosporine component is administered to the patient and an intraocular lens is inserted into an eye of the patient. One or more benefits to the patient may be obtained by practicing the present methods. | 2010-06-10 |
20100144616 | Neuroprotective methods and reagents - One aspect of the present application relates to a method for limiting damage to neuronal cells by ischemic or epoxic conditions, e.g., such as may be manifest by a reduction in brain infarct volume, by administering to an individual a hedgehog therapeutic or ptc therapeutic in an amount effective for reducing cerebral infarct volume. | 2010-06-10 |
20100144620 | COMPLEMENTATION OF FACTOR XI DEFICEINCY BY FACTOR V MUTANTS - Described are methods for preventing and/or treating bleeding in a subject with Factor XI deficiency, such as hemophilia C, which methods comprise administering to the subject APC-resistant Factor V. | 2010-06-10 |
20100144629 | METHOD TO TREAT INFLAMMATION - The present invention relates generally to the fields of pharmacology, and particularly to a method for treating inflammation, particularly inflammation of the respiratory system. The invention provides a method to reduce or ameliorate inflammation, by administering an effective amount of a protein factor originally isolated from thymic tissue, and referred to as T4 immune stimulating factor (TISF). | 2010-06-10 |
20100144662 | AMINOGLYCOSIDE ANTIBIOTICS TARGETING BACTERIAL 16S RIBOSOMAL RNA - The present invention relates to paromamine-based compounds according to formula I having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing a medicament, pharmaceutical preparations and methods for preparing said compounds | 2010-06-10 |
20100144665 | TREATMENT OF STATIN SIDE EFFECTS - The present invention relates generally to treatment of muscle pain and/or fatigue and to methods for treatment of side effects of statin therapy. In particular, the invention relates to the use of certain substituted benzoquinones, eg Coenzymes Q, particularly Coenzyme Q10 (Q10), in therapy. The invention also relates to the use of Q10 in combinative therapy with other agents such as uridine, its biological precursors or salts, esters, tautomers or analogues thereof (“uridine related compounds”). The invention is also directed to compositions, uses and combination packs or kits related to the treatment methods. | 2010-06-10 |
20100144667 | METHODS FOR FUCOIDAN PURIFICATION FROM SEA WEED EXTRACTS - Methods for purifying fucoidan in extracts from brown seaweed are disclosed. In particular, methods of purifying fucoidan in the extract to remove heavy metal ions, bacterial and endotoxin contaminants, and other impurities are disclosed. The methods include the use of a chelating agent, selective precipitation, and filtration. | 2010-06-10 |
20100144692 | Ulipristal Acetate Tablets - The invention relates to a pharmaceutical tablet for oral administration comprising ulipristal acetate together with the following excipients: a diluent in an amount of 60 to 95 wt %, a binding agent in an amount of 1 to 10 wt %, croscarmellose sodium in an amount of 1 to 10 wt %, and magnesium stearate in an amount of 0 to 5 wt %. | 2010-06-10 |
20100144694 | 1,2-DIAZETIDIN-3-ONE DERIVATIVES AND DRUGS CONTAINING SAME | 2010-06-10 |
20100144702 | INDOLE COMPOUND - The purpose of the present invention is to provide a glucokinase activator useful as a pharmaceutical agent such as an agent for the prophylaxis or treatment of diabetes, obesity and the like. The present invention provides a glucokinase activator containing a compound represented by the formula (I): wherein R | 2010-06-10 |
20100144703 | XANTHINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS - Disclosed are substituted xanthines of general formula | 2010-06-10 |
20100144711 | PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION - A pharmaceutical composition for oral administration, comprising 3-hydroxy-N | 2010-06-10 |
20100144715 | Substituted Benzodiazepinones, Benzoxazepinones and Benzothiazepinones as Sodium Channel Blockers - The present invention is directed to substituted benzodiazepinones, benzoxazepinones and benzothiazepinones compounds that are sodium channel blockers useful for the treatment of chronic and neuropathic pain. The compounds of the present invention are also useful for the treatment of other conditions, including disorders of the CNS such as anxiety, depression, epilepsy, manic depression and bipolar disorder. This invention also provides pharmaceutical compositions comprising a compound of the present invention, either alone, or in combination with one or more therapeutically active compounds, and a pharmaceutically acceptable carrier. This invention further comprises methods for the treatment of acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain and disorders of the CNS including, but not limited to, epilepsy, manic depression, depression, anxiety and bipolar disorder comprising administering the compounds and pharmaceutical compositions of the present invention. | 2010-06-10 |
20100144718 | TREATMENT OF DISEASES MODULATED BY A H4 RECEPTOR AGONIST - The invention provides a method for the treatment of H4R modulated diseases and/or conditions comprising administering to the subject an effective amount of a H4R agonist. The invention also provides a method for treating COPD comprising administering to the subject an effective amount of a H4R agonist, a H1R antagonist and an anticholinergic drug. Further, the invention provides a pharmaceutical formulation comprising a H4R agonist, a second active agent and a pharmaceutically acceptable carrier. | 2010-06-10 |
20100144720 | INHIBITORS OF HUMAN TUMOR-EXPRESSED CCXCKR2 - Pharmaceutical compositions containing organic compounds or salts thereof that serve as modulators for the SDF-1 or I-TAC chemokines are disclosed. The compounds and compositions are useful in the treatment of cancer, especially in the inhibition of cancer proliferation, growth, and metastasis. Methods of interfering with SDF-1 and/or I-TAC binding to the CCXCKR2 receptor and treating cancer using the compounds and pharmaceutical compositions of the present invention are also disclosed. | 2010-06-10 |
20100144726 | NOVEL INDOLIC DERIVATIVES, THEIR PREPARATION PROCESSES AND THEIR USES IN PARTICULAR AS ANTIBACTERIALS - The invention relates to the use of at least one compound of the formula (I), | 2010-06-10 |
20100144728 | Oxazolidinone For The Treatment And Prophylaxis Of Pulmonary Hypertension - The present invention relates to the use of factor Xa inhibitors, especially of oxazolidinones of the formula (I), for the treatment and/or prophylaxis of pulmonary hypertension, and to the use thereof for the manufacture of medicaments for the treatment and/or prophylaxis of pulmonary hypertension. | 2010-06-10 |
20100144765 | 5,6-TRIMETHYLENEPYRIMIDIN-4-ONE COMPOUNDS - Pyrimidone compounds of formula (I): | 2010-06-10 |
20100144768 | KINASE INHIBITOR COMPOUNDS - Pyrimidinone derivatives have enhanced and unexpected drug properties as inhibitors of protein kinases and are useful in treating disorders related to abnormal protein kinase activities such as inflammatory diseases and certain types of cancer. | 2010-06-10 |
20100144771 | Novel Hydantoin Derivatives for the Treatment of Obstructive Airway Diseases - The invention provides compounds of formula (I): | 2010-06-10 |
20100144777 | Method of Network-Based Identification of Multicomponent Synergy and Compositions for Use as Effective Component of Anti-Angiogenesis Medicines - A method was provided for determining synergistic effect of a medicine combination including two medicines relating to a disease on the basis of a gene network and medicine-effective genes of each and/or any of said two medicines, comprising: determining a synergy factor (ST | 2010-06-10 |
20100144780 | Salts and Mixture of 9-Oxoacridine-10-Acetic Acid with 1-Alkylamino-1-Desoxy-Polyols, Pharmaceutical Compositions Containing Said Agents and Treatment Methods - The invention relates to salts of 1-alkylamino-1-deoxypolyols and 9-oxoacridine-10-acetic acid of the general formula (I): | 2010-06-10 |
20100144792 | NEURITE FORMATION PROMOTER - The invention provides an agent for promoting ocular tissue neuritogenesis, containing N-(1-acetylpiperidin-4-yl)-4-fluorobenzamide or a pharmaceutically acceptable salt thereof, and an agent for promoting corneal neuritogenesis and retinal neuritogenesis, containing N-(1-acetylpiperidin-4-yl)-4-fluorobenzamide or a pharmaceutically acceptable salt thereof. The corneal neuritogenesis promoter can be used for the improvement of corneal sensitivity, treatment of dry eye, or treatment of a corneal epithelial disorder. The retinal neuritogenesis promoter can be used for the improvement of a visual dysfunction. | 2010-06-10 |
20100144800 | EXTENDED RELEASE TABLET FORMULATION OF NIACIN - The present invention relates to an extended release tablet formulation comprising niacin and a release retarding agent selected from hydroxypropyl cellulose, polyethylene oxide or mixtures thereof. | 2010-06-10 |
20100144818 | 1-BENZYLPYRAZOLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF - The present invention relates to compounds corresponding to formula (I): | 2010-06-10 |
20100144820 | THERAPEUTIC HPPH DOSAGE FOR PDT - A method for treating cancer and other hyperproliferative tissues in humans that can be exposed to light comprising injection of HPPH at the equivalent to a dose of 0.05 to 0.11 mg/kg of body weight 24 hours post injection and exposing the tumor or other hyperproliferative tissue to 665±10 nm of light at 50 to 200 Joules/cm | 2010-06-10 |
20100144833 | RNAi Modulation Of RSV, PIV And Other Respiratory Viruses And Uses Thereof - The present invention is based on the in vivo demonstration that RSV and PIV can be inhibited through intranasal administration of RNAi agents as well as by parenteral administration of such agents. Further, it is shown that effective viral reduction can be achieved with more than one virus being treated concurrently. Based on these findings, the present invention provides general and specific compositions and methods that are useful in reducing RSV or PIV mRNA levels, RSV or PIV protein levels and viral titers in a subject, e.g., a mammal, such as a human. These findings can be applied to other respiratory viruses. | 2010-06-10 |
20100144839 | ANTI-CANCER OLIGODEOXYNUCLEOTIDES - It is disclosed herein that suppressive ODNs are of use for preventing or delaying the formation of a tumor, reducing the risk of developing a tumor, treating a tumor, preventing conversion of a benign to a malignant lesion, or preventing metastasis. In some embodiments, methods are disclosed herein for treating, preventing or reducing the risk of developing a tumor, such as esophageal, gastrointestinal, liver, lung, skin and colon tumors or a mesothelioma. Generally, the methods disclosed herein include selecting a subject for treatment and administering to the subject a therapeutically effective amount of one or more suppressive ODN. In some examples, additional agents can also be administered to the subject of interest. | 2010-06-10 |
20100144861 | Perfluorocarbon gel formulations - A perfluorocarbon gel composition is disclosed with numerous uses including topical medical and cosmetic uses. | 2010-06-10 |
20100144866 | ANTI-FATIGUE AGENTS AND ORAL COMPOSITIONS CONTAINING ANDROGRAPHOLIDE AS ACTIVE INGREDIENT - Disclosed is a composition which is safe for a human body and an animal, can be ingested continuously on a daily basis, has an anti-fatigue activity, and is effective for the prevention or treatment of a disease or condition associated with fatigue. Specifically disclosed is an anti-fatigue agent comprising andrographolide optionally together with an α-lipoic acid as an active ingredient(s). Also disclosed is a novel oral composition comprising andrographolide and an α-lipoic acid. The anti-fatigue agent and the oral composition are useful for the prevention or treatment of chronic fatigue syndrome, overfatigue, physical fatigue, mental fatigue and organ fatigue. | 2010-06-10 |
20100144870 | CHEMICAL COMPOSITIONS AND METHODS OF MAKING THEM - Bimetal chelates are prepared from a solution formed by adding to a solvent one or more polyfunctional acids with basic salts of two or more coordination elements listed in Groups IIIA to VIIIA, Groups IB to IIIB, of periods 4 and 5 and aluminum in Group IIIB, period 3 of The Periodic Table of the Elements and recovering the chelate. Such chelates can be used to formulate useful products. | 2010-06-10 |
20100144881 | CRYSTALLINE FORMS OF A 3-CARBOXYPROPYL-AMINOTETRALIN COMPOUND - The invention provides crystalline solid forms of (S)-4-((2S,3S)-7-carbamoyl-1,1-diethyl-3-methoxy-1,2,3,4-tetrahydronaphthalen-2-ylamino)-2-cyclohexylmethyl-butyric acid. The invention also provides pharmaceutical compositions comprising such crystalline solid forms, methods of using such crystalline solid forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline solid forms. | 2010-06-10 |
20100144883 | TOPICALLY APPLICABLE COMPOSITIONS FOR THE TREATMENT OF KERATINIZATION DISORDERS - Topical compositions containing from 0.01% to 0.09% by weight of adapalene or salts thereof are useful for the treatment or prevention of keratinization disorders, particularly acne, and additionally contain at least one gelling agent selected from among carbomers, polysaccharides, cellulose and its derivatives, copolymers of acrylate and of alkyl acrylate, copolymers of acrylamide and of sodium acrylamido-2-methylpropanesulfonate, and xanthan gum. | 2010-06-10 |
20100144887 | Crystalline solid rasagiline base - The subject invention provides crystalline R(+)-N-propargyl-1-aminoindan, pharmaceutical compositions and methods of manufacture thereof. | 2010-06-10 |
20100144901 | Gel composition for medical material or hygiene material, molded article thereof and adhesive material or adhesive preparation using same - The present invention can provide a composition for a medical material or a hygiene material, which can retain a considerable amount of a chemical substance such as a drug and the like or an organic liquid component, is associated with less limitation on molding, does not easily drop off when adhered to the skin, provides a better feeling during adhesion to the skin, produces decreased adhesive residue when detached from the skin, and shows good followability to the skin. The present invention provides a gel composition obtained by crosslinking a composition for gel preparation comprising a liquid rubber having a crosslinkable functional group in a molecule and 34.6-64.6 wt % of an organic liquid component relative to the total weight of the composition for gel preparation. | 2010-06-10 |
20100144903 | METHODS OF DIAGNOSIS AND TREATMENT OF CROHN'S DISEASE - In one embodiment, this invention provides methods of diagnosing and/or predicting susceptibility to Crohn's Disease by determining the presence or absence of risk haplotypes in IL23R, IL17A, IL17RA and/or IL12RB1 locus. In another embodiment, the invention provides methods of diagnosing and/or predicting susceptibility to Crohn's Disease in an individual by determining the presence or absence of risk haplotype at the IL12RB2 locus. | 2010-06-10 |
20100144922 | PROCESS FOR PREPARING AN AQUEOUS COMPOSITE-PARTICLE DISPERSION - A process for preparing aqueous dispersions of composite particles using monomers containing silane groups. | 2010-06-10 |
20100144923 | POLYMER COMPOSITIONS WITH IMPROVED MECHANICAL PROPERTIES - The invention concerns thermoplastic materials with improved mechanical properties, comprising a matrix and inclusions. The materials comprise at least two families of inclusions defined by their type, shape and dimensions and optionally by their concentration. The materials can in particular be used for making molded thermoplastic articles. | 2010-06-10 |
20100144926 | EPOXY RESIN COMPOSITION - A resin composition comprising an epoxy compound denoted by the formula (1): | 2010-06-10 |
20100144928 | Curable Epoxy Resin Composition, Cured Body Thereof, and Use Thereof - A curable epoxy resin composition comprising at least the following components: (I) an epoxy resin; (II) a curing agent for an epoxy resin; (III) a diorganosiloxane having on both molecular terminals siloxane residual radicals represented by the following average unit formula: (XR | 2010-06-10 |
20100144960 | Release Coating Compositions Having Improved Release Force Profiles - A composition containing (A) a compound having at least one aliphatic unsaturation; (B) a cyclic organohydrogen-silicon crosslinking compound containing at least one silicon-bonded hydrogen atom (Sift) per molecule, prepared by a platinum catalyzed coupling reaction of a methylhydrogen cyclosiloxane, with a reactant containing aliphatic unsaturation, hydroxy functionalities, or a mixture of both; and (B1) a linear or branched acyclic organohydrogensilicon Crosslinking compound containing at least one silicon-bonded hydrogen atom per molecule. The composition can be used to prepare release coating compositions by adding (C) a platinum group metal-containing catalyst. Release coating compositions containing Components (B) and (B1) have better cure, better adhesion, and lower release forces, than release coating compositions containing only Component (B). | 2010-06-10 |
20100144974 | POLYPROPYLENE-BASED COPOLYMER AND FILM COMPRISING THE POLYPROPYLENE-BASED COPOLYMER - A polypropylene-based copolymer containing 50 to 95% by weight of a polymer component comprising 95% by weight or more of the constitutional unit derived from propylene and having a melting point exceeding 155° C. (component A) and 5 to 50% by weight of a copolymer component of propylene, ethylene and an α-olefin having 4 or more carbon atoms (component B) in which the content of the constitutional unit derived from propylene (X) is 10% by weight≦X<50% by weight, the content of the constitutional unit derived from ethylene (Y) is 50% by weight2010-06-10 | |
20100144976 | FUNCTIONALIZED POLYFLUORENES FOR USE IN OPTOELECTRONIC DEVICES - The present invention relates to process comprising reacting a polyfluorenes comprising at least one structural group of formula I | 2010-06-10 |
20100144977 | CURING AGENTS FOR EPOXY RESINS - A variety of curing agents for epoxy resins and methods for preparation thereof are disclosed, including compounds having the structures of formulas III and IV: | 2010-06-10 |
20100144991 | Electron Donor Composition For A Solid Catalyst, Solid Catalyst Composition Used In The Polymerisation Of A-Olefins, And Process For The Production Of A Polymer Consisting Of A-Olefin Units Using The Solid Catalyst Composition - An electron donor composition comprising a dihydroanthracene derivative and a phthalate ester. Furthermore, a solid catalyst composition comprising the electron donor composition for use in α-olefin polymerisation. Further, a process for the production of a polymer containing α-olefin monomer units with the electron donor composition. | 2010-06-10 |
20100144995 | METHOD FOR PRODUCING THERMOPLASTIC RESIN, POLYESTER RESIN AND POLYCARBONATE RESIN, AND THEIR APPLICATIONS - The invention relates to a method for producing a thermoplastic resin, comprising using a composition at least comprising a fluorene-containing dihydroxy compound represented by the following formula (1) and a fluorene-containing hydroxy compound represented by the following formula (2) in an amount of from 0.5 parts by weight to 1.5 parts by weight relative to 100 parts by weight of the fluorene-containing dihydroxy compound of formula (1). | 2010-06-10 |
20100144997 | Copolymer Rubber, Rubber Composition and Rubber Molded Product - The invention provides a copolymer rubber excellent in processability in kneading and processability in extrusion; rubber compositions containing the rubber; and crosslinked moldings of the compositions excellent in sealing properties and shape retention. A random copolymer rubber of ethylene (A), a C | 2010-06-10 |
20100145032 | NOVEL CARBOHYDRATE PROFILE COMPOSITIONS FROM HUMAN CELLS AND METHODS FOR ANALYSIS AND MODIFICATION THEREOF - The invention describes reagents and methods for specific binders to glycan structures of stem cells. Furthermore the invention is directed to screening of additional binding reagents against specific glycan epitopes on the surfaces of the stem cells. The preferred binders of the glycans structures includes proteins such as enzymes, lectins and antibodies. | 2010-06-10 |
20100145036 | CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF - The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them. | 2010-06-10 |
20100145037 | DNA AMPLIFICATION AND SEQUENCING USING DNA MOLECULES GENERATED BY RANDOM FRAGMENTATION - The present invention is directed to methods to prepare a DNA molecule or a plurality of DNA molecules by random fragmentation. In some embodiments, the present invention regards preparing a template for DNA sequencing by random fragmentation. In specific embodiments, the random fragmentation comprises chemical fragmentation, mechanical fragmentation, or enzymatic fragmentation. In further specific embodiments, a universal sequence is attached to the 3′ end of the DNA fragments, such as by ligation of an adaptor sequence or by homopolymeric tailing with terminal deoxynucleotidyltransferase. In other embodiments, a library is prepared with methods of the present invention. | 2010-06-10 |
20100145049 | PROCESS FOR MAKING N-(DIPHENYLMETHYL)PIPERAZINES - A compound of formula (8) or a salt thereof: | 2010-06-10 |
20100145050 | ORTHOGONALLY FIXED COMPOUNDS FOR ELECTROOPTICAL APPLICATIONS - The present invention relates to chemical compounds that can be used in electrooptical applications. The electrically conductive and optical properties of these compounds, e.g. hole transporting, electron transporting and/or light emitting properties can be predetermined by substituting the core structure of these compounds with respective residues. The core structure ( | 2010-06-10 |
20100145063 | 2- thioethenyl substituted carbapenem derivatives - 2-Ethenylthio-type carbapenem derivatives of formula (I) or pharmaceutically acceptable salts thereof are provided. The compounds according to the present invention have potent antimicrobial activity and a wide antimicrobial spectrum against pneumococci including penicillin resistant | 2010-06-10 |
20100145083 | PREPARATION OF BILE ACIDS AND INTERMEDIATES THEREOF - Synthetic methods for preparing deoxycholic acid and intermediates thereof are provided. | 2010-06-10 |
20100145084 | Methods for obtaining bioactive compounds from phytoplankton - Phytoplankton represent a potential source of bioactive compounds. The present disclosure provides, inter alia, methods for identifying glycerolipids and apoptosis-inducing sphingosine-like lipids from virally-infected phytoplankton. | 2010-06-10 |
20100145091 | CONVERSION OF NITRILE COMPOUNDS INTO CORRESPONDING CARBOXYLIC ACIDS AND ESTERS - Hydrocarbon compounds having at least one nitrile function are converted into compounds having at least one carboxylic function by hydrating the nitrile functions into amide functions by reaction with water in the presence of a strong inorganic acid, and then hydrolyzing the amide functions into carboxylic functions by reaction with water and a strong inorganic acid; the carboxylic compounds thus obtained can be esterified into diesters, advantageously diester solvents. | 2010-06-10 |
20100145092 | METHOD FOR THE SYNTHESIS OF (METH)ACRYLIC ESTERS CATALYSED BY A POLYOL TITANATE - The subject of the invention is a method for the synthesis of (meth)acrylic esters by transesterification in the presence of a catalyst corresponding to the formula [(R′O) | 2010-06-10 |
20100145094 | Process and Catalyst for Oxidizing Aromatic Compounds - Catalytic compositions for conversion of substituted aromatic feed materials to oxidized products comprising aromatic carboxylic acid derivatives of the substituted aromatic feed materials comprise solid particles comprising palladium in combination with at least one of antimony, bismuth and gold, and optionally, an additional metal or metalloid component effective to promote activity or selectivity of the palladium and antimony, bismuth or gold for oxidation to aromatic carboxylic acids. A process for oxidizing substituted aromatic feed materials comprises contacting the feed material with oxygen in the presence of such catalytic compositions in a liquid reaction mixture. | 2010-06-10 |
20100145097 | Preparation of acetic acid - A process for producing acetic acid is disclosed. The process comprises carbonylating methanol to form a reaction mixture and flashing the reaction mixture to form a vapor stream and a liquid stream. The flash tank is equipped with a distillation column. The vapor stream comprises acetic acid and other volatile components but essentially no catalyst. The liquid stream comprises the catalyst and sufficient amounts of water and acetic acid to carry and stabilize the catalyst. The liquid stream is recycled to the carbonylation and the vapor stream is subjected to further separation to produce essentially pure acetic acid. | 2010-06-10 |
20100145100 | PROCESS FOR THE PREPARATION OF AMINES - The present invention relates to a process for the preparation of syn-enriched 5-amino-9-isopropyl-benzonorbomene in which the ratio of compounds of formula (Ia(syn)) to compounds of formula (Ib(anti)) is from 70:30 to 99:1, which process comprises reacting a compound of formula (Il) in a pressure vessel with hydrogen in the presence of a palladium catalyst and a solvent, at a pressure of at least 2 bar and a temperature of from 00 C to 45° C., to form syn-enriched 5-amino-9-isopropyl-benzonorbomene. | 2010-06-10 |
20100145105 | NOVEL PHENYLBORONIC ACID COMPOUNDS AND INTERMEDIATES AND PROCESSES FOR THE PREPARATION THEREOF - Vitamin D derivatives, notably non-steroidal vitamin D derivatives, are prepared from novel disubstituted phenylboronic acid compounds having the formula (I): | 2010-06-10 |
20100145109 | METHOD FOR PREPARING DINITROTOLUENE - The present invention relates to a process for preparing dinitrotoluene. The process of the invention for preparing dinitrotoluene from mononitrotoluene, which comprises carrying out a mononitrotoluene nitration reaction using a nitrating mixture comprising nitric acid, sulphuric acid and water resulting in a two-phase medium and separating the organic and aqueous phases of said two-phase medium, is characterized in that the mononitrotoluene nitration is carried out using a nitrating mixture comprising at most 10% by weight of water resulting in a two-phase medium, in that the organic and aqueous phases of said two-phase medium are separated, and in that the aqueous phase derived from the separating operation is recycled, at the end of the mononitrotoluene nitration reaction and before the separation of the organic and aqueous phases, such that the weight ratio of the aqueous phase to the organic phase is at least equal to 1.2. | 2010-06-10 |
20100145110 | Conversion of fluorocarbons - A process is disclosed for the conversion of fluorocarbons into fluorinated unsaturated compounds useful as monomers or other chemical precursors, such as C | 2010-06-10 |
20100145125 | PROCESS OF PRODUCING LIGHT OLEFINS THROUGH THE CONVERSION OF METHANOL AND ETHANOL - The present invention discloses a process of producing light olefins through the conversion of methanol and ethanol. The process comprises: feeding a first portion of a feed via a distributor at the bottom of a fluidized-bed reactor to a reaction zone containing a catalyst; feeding a second portion of the feed from at least one location above the distributor to the reaction zone; contacting the feed with the catalyst and allowing it to react, to give a stream containing ethylene and propylene; and withdrawing the stream containing ethylene and propylene from the top of the reactor, and passing it to a separation system to separate ethylene and propylene, wherein the first portion of the feed and the second portion of the feed comprises each independently methanol or ethanol or the both, with a proviso that the total feed comprises both methanol and ethanol, and a weight ratio of methanol to ethanol in the total feed is in a range of from 99:1 to 0.1:1. | 2010-06-10 |
20100145161 | SYSTEM AND METHOD FOR REMOTE AND MOBILE PATIENT MONITORING SERVICE USING HETEROGENEOUS WIRELESS ACCESS NETWORKS - A system and method for remote and mobile patient monitoring service is provided using heterogeneous wireless access in which each patient is equipped with a remote monitoring device with a heterogeneous wireless transceiver. This can be a value-added service provided by a Healthcare service provider (i.e., a hospital or healthcare center) for which the Healthcare service provider can pay to the wireless network service provider (i.e., a network operator). With heterogeneous wireless access, a remote/mobile patient can use different types of wireless technologies (e.g., WiMAX-based WMAN and WiFi-based WLAN technologies) to transfer monitored bio-signal data to the healthcare center. The monitoring device can buffer and then transmit the bio-signal data to the healthcare center through the heterogeneous radio access network. In this device, there can be two buffers used to store bio-signal data, each with different priority. The scheduler in this device can make an optimal decision on data transmission. Also, a method is provided to minimize the cost of network connections for remote/mobile patient monitoring. | 2010-06-10 |
20100145163 | Patient Monitoring Apparatus - A patient monitoring system including a sensing-recording device that attaches to a patient and a probe utilized by attending personnel at a trauma site. After an initial interaction between the probe and the sensing-recording device, the sensing-recording device samples one or more physiological parameters and stores time stamped readings in a first memory. The probe is adapted to take other measurements, download the data from the first memory of the sensing-recording device, manipulate the collective data and return data to a second memory in the sensing-recording device. The sensing-recording device continues to accumulate data in the first memory during transport of the patient from a trauma site to a medical facility. | 2010-06-10 |
20100145165 | Notification System - The invention relates to a process and apparatus for notifying medical staff that an event or action is due on the basis of one or more physiological variation of a patient. In particular the invention relates to a notification system for anaesthetists to provide medication. | 2010-06-10 |
20100145168 | Method for assessing endothelial function - The system assesses the endothelial function of a subject. Particularly, peripheral tissue perfusion measurements taken in a subject are compared to reference perfusion data and the comparison yields the assessment of endothelial function. The reference may be data indicative of peripheral tissue perfusion in a healthy person. Also, peripheral tissue perfusion measurements taken in a subject when perfusion is in an unperturbed state (the reference) can be compared to perfusion measurements taken promptly after a challenge to normal or unperturbed tissue perfusion of the subject. | 2010-06-10 |
20100145175 | SYSTEMS AND METHODS FOR VERIFICATION OF SAMPLE INTEGRITY - Disclosed are methods and apparatus for determining analyte concentration in a sample such as bodily fluid. Systems and methods disclosed herein can include an additive system for adding an additive to a sample to reduce the adverse affects of bubbles and microbubbles in the sample. Some systems and methods disclosed herein include performing an auxiliary measurement cycle in the event of a failure of a scheduled measurement cycle. Some systems and methods disclosed herein include a measurement system configured for use with multiple patients. | 2010-06-10 |
20100145177 | Stapedius Muscle Electrode - The invention relates to a stapedius muscle electrode array for detecting the action elements generated when a human stapedius muscle is contracted. Said array comprises an electrode ( | 2010-06-10 |
20100145187 | Catheter - So that a catheter can be made visible in ultrasound images easily and with relatively little effort, and hence positional control of a catheter can be enabled with relatively little effort, an ultrasound marking recognizable in the body of a living being by means of ultrasound is provided at the distal end of a catheter, wherein the catheter has a lumen, and the ultrasound marking is arranged in the lumen near the distal end such that it is removable via a proximal end of the catheter. | 2010-06-10 |
20100145188 | IMAGING DIAGNOSTIC DEVICE, MEASUREMENT POINT SETTING METHOD, AND PROGRAM - An image diagnostic device of the present invention includes image display means ( | 2010-06-10 |
20100145202 | METHOD AND APPARATUS FOR DETERMINING INFORMATION CONCERNING THE IDENTITY OF AN INDIVIDUAL - A method of determining information concerning the identity of an individual comprising measuring at least one biometric of the individual comprising at least one bio-potential waveform generated by the individual's heart, extracting a plurality of characteristics from the bio-potential waveform comprising any of an approximate location of a point of a P peak, an approximate location of a Q-point of a QRS peak system, an approximate location of an R-point of a QRS peak system, an approximate location of an S-point of a QRS peak system, an approximate location of a point of a T peak, using the characteristics to calculate at least one waveform parameter, comparing at least one calculated waveform parameter with at least one previously-acquired waveform parameter to generate a score, and using the score to determine information concerning the identity of the individual. | 2010-06-10 |
20100145204 | ALTERNANS AND PHARMACOLOGICAL AGENTS - First cardiac signal data generated from measured heart beats of a subject is received. Characteristics of alternans occurring in the received first cardiac signal data are determined. Second cardiac signal data generated from measured heart beats of the subject after a change relating to an administration of a pharmacological agent is received. Characteristics of alternans occurring in the received second cardiac signal data are determined. The characteristics of alternans occurring in the received first cardiac signal data are compared with the characteristics of alternans occurring in the received second cardiac signal data. | 2010-06-10 |
20100145231 | System for measuring space width of joint, method for measuring space width of joint and recording medium - A method for measuring space width of joint includes: a joint image input step of inputting an image of a joint; a contour detecting step of detecting contours of a pair of bones constituting the joint; a measurement range setting step of setting a measurement range of a space of the joint based on the contours detected in the contour detecting step; a space width calculating step of calculating a space width which is a distance between the pair of bones within the measurement range set in the measurement range setting step; and a display step of displaying the space width calculated in the space width calculating step. | 2010-06-10 |
20100145233 | SYSTEM AND METHOD FOR TRAINING HUMAN SUBJECTS TO IMPROVE OFF-AXIS NEUROMUSCULAR CONTROL OF THE LOWER LIMBS - Anterior cruciate ligament (ACL) is the most commonly injured knee ligament in sports-related activities, especially in pivoting sports. Considering that the knee is free to flex/extend but has much more limited motions about the off-axis (tibia rotation and valgus/varus), ACL injuries are often associated with excessive off-axis loadings. A pivoting/sliding mechanism combined with sagittal plane movement/exercise is described as a diagnostic tool to evaluate off-axis neuromechanical and anatomical risk factors of noncontact ACL injuries. The pivoting/sliding mechanism is also described as an intervention tool for off-axis training, possibly based on the diagnosis, to reduce the incidence of ACL injuries. Training outcome can also be evaluated using the pivoting/sliding mechanism. In general, the pivoting/sliding mechanism can be used with many sagittal plane exercise machines and used to improve off-axis control of the lower limbs and reduce lower limb injuries. | 2010-06-10 |
20100145237 | FITNESS DEVICE - The inventive fitness device is embodied in the form of an article of clothing, consisting of a pair of trousers, for example, consisting of an airtight outer skin ( | 2010-06-10 |
20100145271 | METHOD TO SENSE TEMPERATURE IN AN IMPLANTABLE PUMP - An implantable drug infusion pump for delivering drug therapy is made more reliable and its performance improved by monitoring drug pump temperature. Monitoring pump temperature can also provide for temperature-related drug therapy modification. | 2010-06-10 |
20100145277 | CANNULA - A cannula ( | 2010-06-10 |
20100145281 | Harness Interface Conduit, Tether Line, and Swivel for Use in Animals - A harness for use in coupling with an animal interface, the animal interface comprising one or more of conduits for transmitting fluid, electrical signals, or optical signals. Swivel extension tether for quick connect to harness, dual-ended swivel, an extension line, and connection to upstream monitoring equipment. Method for using the harness in an animal for fluid communication access, an electrical signal interface, and an optical interface. | 2010-06-10 |
20100145287 | ASSEMBLY FOR CONDITIONING AND DISPENSING A MEDICAL LIQUID - This assembly is of the type including: a vessel ( | 2010-06-10 |
20100145291 | DEODORIZING FILTER AND EXCRETA RECEPTACLE HAVING THE SAME - [Problem] To provide a deodorizing filter that even in long-term use, is free from clogging by excrements and can maintain a favorable gas venting function, and to provide an excrements collector having the deodorizing filter. | 2010-06-10 |
20100145297 | SINGLE DOSE MEDICATION CONTAINER - A portable shatter-proof container for liquid medication is adapted for measuring, labeling, and dispensing single dosages of prescribed medication. The apparatus is comprised of a three-dimensional graduated tube having a snap-closure lid and a base for allowing the apparatus to stand upright. The tube has graduated marks in imperial and metric measurements and can hold a reasonable volume, i.e. one dose, of liquid. With its rectangular shape, the narrow length contains the graduated markings of imperial measurement on one side and metric markings on the opposing side. The wider front includes an adhesive label for writing information such as patient name, date, contents, and dosing instructions. Liquid medicine is poured directly from the original medicine bottle into the apparatus, thereby allowing for measurement of contents as it is filled. The snap-closure lid allows the container to be transported, without concern of spillage. The contents are then consumed by drinking the measured liquid from the disposable container. | 2010-06-10 |
20100145332 | SURGICAL SYSTEM AND SURGICAL METHOD - A surgical system includes: a treatment portion for treating living body tissue targeted for treatment; an ultrasound supplying section for supplying ultrasound via ultrasound transducers which produce ultrasound vibration; a radio-frequency electrical power supplying section for supplying, to the treatment portion, radio-frequency electrical power having an output wave-form defined by a base frequency and a repetition frequency; and a controlling section for controlling at least one of a voltage root-mean-square value and a crest factor, so that the voltage peak value of the output wave-form of the radio-frequency electrical power does not exceed a fixed value. | 2010-06-10 |
20100145333 | Light emitting electrosurgical scalpel - An improved electrosurgical scalpel, with light emission, for generating electrical signals intended for applications to the body of a patient via an electrosurgical electrode is provided. An electrosurgical scalpel includes a handle with a receptacle portion of a conductive member for mounting and retaining an electrode blade, a light source with a power source encapsulated within the handle and a means to direct the light emitted outwardly towards the electrode tip. Operation of a switch on the handle to an on position serves to complete a circuit, activating the light source and, thereby directing light through an opening or upper portion and out from the first end of the handle towards the distal end of the electrode blade. | 2010-06-10 |
20100145343 | APPARATUS AND METHOD FOR SCULPTING THE SURFACE OF A JOINT - Methods and devices for sculpting bones, particularly in preparation for implanting prosthetic devices to replace articulating bone joint surfaces. Improved bone removal devices including burr mills driven by gears and loop drives are provided. Reciprocating cutters and belt cutters are also provided. Some devices have either integral or removable expandable portions to vary the force and bone resection depth. Devices can have irrigation ports and plenums to remove bone fragments. Some cutters are dual cutters, adapted to remove bone in two or more regions, such as the knee joint, simultaneously. | 2010-06-10 |
20100145350 | Syringe Plunger Seal - A bone filler delivery device includes a syringe assembly. The syringe assembly has a barrel with a first opening for dispensing bone filler and a second opening adapted to receive a plunger. A plunger is adapted to mate with the barrel to define a bone filler dispensing chamber therein. The plunger can move through the barrel in an axial direction. A seal is coupled to the plunger and is adapted to seal against the barrel. The seal includes an annular body and an annular first lip that extends from the body in a first direction and is adapted to flex toward the barrel when the plunger is moved through the barrel toward the first opening. | 2010-06-10 |
20100145371 | Embolectomy Catheters And Methods For Treating Stroke And Other Small Vessel Thromboembolic Disorders - Embolectomy catheters, rapid exchange microcatheters, systems and methods for removing clots or other obstructive matter (e.g., thrombus, thromboemboli, embolic fragments of atherosclerotic plaque, foreign objects, etc.) from blood vessels. This invention is particularly useable for percutaneous removal of thromboemboli or other obstructive matter from small blood vessels of the brain, during an evolving stroke or period of cerebral ischemia. In some embodiments, the embolectomy catheters of this invention are advanceable with or over a guidewire which has been pre-inserted through or around the clot. Also, in some embodiments, the embolectomy catheters include clot removal devices which are deployable from the catheter after the catheter has been advanced at least partially through the clot. The clot removal device may include a deployable wire nest that is designed to prevent a blood clot from passing therethrough. The delivery catheter may include telescoping inner and outer tubes, with the clot removal device being radially constrained by the outer tube. Retraction of the outer tube removes the constraint on the clot removal device and permits it to expand to its deployed configuration. An infusion guidewire is particularly useful in conjunction with the embolectomy catheter, and permits infusion of medicaments or visualization fluids distal to the clot. | 2010-06-10 |
20100145374 | SYSTEM FOR OPERATING AND CONTROLLING A PNEUMATICALLY DRIVEN VITRECTOMY PROBE - A pneumatically driven vitrectomy probe system includes a movable member disposed within a cylinder to define an enclosed pressure chamber, which has an inlet and an outlet. A pressure transducer senses the pressure level within the enclosed pressure chamber, and a valve communicates pressurized air to the inlet of the enclosed pressure chamber based on the pressure level. A displacement device coupled to the movable member extends and retracts the movable member within the enclosed pressure chamber, to respectively increase and decrease the pressure level of pressurized air communicated via the chamber outlet. The pressurized air is communicated to enclosed volume within a pneumatically activated vitrectomy probe, which includes a hollow inner cutting member disposed within the hollow outer member. Upon extension of the displacement member, the resulting increase in pressure level of the pressurized air in the enclosed volume acts against the biasing spring to move the hollow inner cutting member, to cut vitreous material extending within the hollow outer member. | 2010-06-10 |
20100145377 | Lancing Device For Minimizing Pain - The present invention provides a lancing device designed for minimizing pain to the user, comprising a probe with cam profile responsible for controlling the lancet speed such that the lancet enters the skin relatively fast, decelerates smoothly and gradually to zero velocity at maximum depth of penetration and retracts slowly and controllably. The housing of the lancet comprises of leaf springs and set of guides for minimizing or eliminating pitching or vibration of the lancet during lancing, hence reducing the pain experienced by the user. The lancing device is further equipped with a gear-damper system for minimizing or eliminating noise produced during lancing process. | 2010-06-10 |
20100145378 | Percutaneous Gastroplasty - Disclosed are methods and apparatus for implantation into the walls of an organ such as the stomach. Deformable or inflatable anchors with a connector between are used to pull the walls of the organ together, or to implant devices in the wall of the organ. Also disclosed are surgical instruments useful in practicing the disclosed methods. | 2010-06-10 |
20100145380 | THROMBOSIS FILTER WITH COVER LAYER - A method is provided for applying a cover layer ( | 2010-06-10 |
20100145405 | Systems and Methods for Controlling Ventricular Pacing in Patients with Long Inter-Atrial Conduction Delays - Techniques are provided for use by implantable medical devices for controlling ventricular pacing. In one example, optimal atrio-ventricular and interventricular pacing delay values are determined for pacing the heart of the patient based, in part, on a measured inter-atrial conduction delay. Atrio-ventricular conduction delays are then measured within the patient. The atrio-ventricular pacing delays are compared with the measured atrio-ventricular conduction delays. If the atrio-ventricular pacing delays are less than the measured atrio-ventricular conduction delays, biventricular pacing is delivered using the atrio-ventricular pacing delay and the interventricular pacing delay. However, if the atrio-ventricular pacing delays are not less than the corresponding atrio-ventricular conduction delays, as can occur if the inter-atrial conduction delay is large, then alternative pacing regimes are selectively enabled, such as monoventricular pacing in the chamber having the longer conduction delay value, biventricular pacing with negative hysteresis, or biventricular pacing with pacing delays reduced using predetermined offset values. | 2010-06-10 |
20100145408 | Splanchnic Nerve Stimulation For Treatment of Obesity - A method for the treatment of obesity or other disorders by electrical activation or inhibition of the sympathetic nervous system is disclosed. This activation or inhibition can be accomplished by stimulating the greater splanchnic nerve or other portion of the sympathetic nervous system using an electrode. This nerve activation can result in reduced food intake and increased energy expenditure. | 2010-06-10 |