22nd week of 2010 patent applcation highlights part 56 |
Patent application number | Title | Published |
20100137586 | Process for the Preparation of Gefitinib - There is provided a compound of formula (III), and a process for preparing a compound of formula (V) comprising converting a compound of formula (III) to the compound (V), wherein (X) is fluoro, chloro, bromo or iodo. There is also provided a process for preparing a compound of formula (XI) comprising converting a compound of formula (X) to the compound (XI). The compounds (V) and (XI) so prepared may be used in a process for preparing gefitinib. | 2010-06-03 |
20100137587 | Heterocyclic compound and use thereof - Compounds represented by the formulas | 2010-06-03 |
20100137588 | METHOD FOR PREPARING ORTHO-SUBSTITUTED AMINOFERROCENES - The present disclosure relates to a method for preparing an ortho-substituted aminoferrocene comprising reacting an aminoferrocene with a Lewis acid and a lithiating reagent in the presence of an electrophile to form the ortho-substituted aminoferrocene. | 2010-06-03 |
20100137589 | GAS SCRUBBER AND USE OF THE GAS SCRUBBER IN MELAMINE PRODUCTION - In a gas scrubber, a gas stream containing at least one sublimed substance is brought in contact with a liquid or melt stream containing at least one thermally convertible substance, which has a lower temperature than the gas stream. For the intensive and intimate mixing of the gas stream with the liquid or melt stream, an orifice plate with a plurality of holes each surrounded by a retaining edge is provided in the upper part of the gas scrubber, and above the orifice plate inlets for the gas stream and the liquid or melt stream are provided. | 2010-06-03 |
20100137590 | N[S(4-ARYL-TRIAZOL-3-YL)alpha-MERCAPTOACETYL] -P-AMINO BENZOIC ACIDS AS HIV REVERSE TRANSCRIPTASE INHIBITORS - A series of S-triazolyl α-mercaptoacetanilides having N-(α-mercaptoacetyl) p amino benzoic acid derivatives. | 2010-06-03 |
20100137591 | PROCESS FOR PREPARING 3-METHYL-4-PHENYLISOXAZOLO [3,4-D]PYRIDAZIN-7(6H)-ONE - A process for preparing 3-methyl-4-phenylisoxazolo[3,4-d]pyridazin-7(6H)-one which process comprises the steps of: (a) reacting 1-phenylbutane-1,3-dione with ethyl 2-chloro-2-(hydroxyimino)actetate; and (b) subsequently reacting the product from step (a) with hydrazine or an hydrate thereof to yield 3-methyl-4-phenylisoxazolo-[3,4-d]pyridin-7(6H)-one, wherein step (b) is carried out on the mixture resulting from step (a) without isolating ethyl 4-benzoyl-5-methylisoxazole-3-carboxylate therefrom. | 2010-06-03 |
20100137592 | PROCESS FOR PREPARING PURINE DERIVATIVE - A process for the preparation of famciclovir a compound of Formula (I) and its intermediates. | 2010-06-03 |
20100137593 | CRYSTALS OF PHENYLALANINE DERIVATIVES AND PRODUCTION METHODS THEREOF - The present invention provides crystals of phenylalanine derivatives of the formula (I): | 2010-06-03 |
20100137594 | TETRAZOYLOXIME DERIVATIVE AND PLANT DISEASE CONTROL AGENT - According to the present invention, a tetrazoyloxime derivative and a salt thereof, which are excellent in a control effect against plant disease injury, and a plant disease controlling agent containing the same as an active ingredient are provided. The tetrazoyloxime derivative has a structure represented by formula (1) shown below: | 2010-06-03 |
20100137595 | VAGINAL ODORANTS - Use vaginal odorant compounds for controlling motile cell chemotaxis. | 2010-06-03 |
20100137596 | Photochromic diarylethene containing coordination compounds and the production thereof - Diarylethene-containing ligands and their coordination compounds are described. The ligands display photochromism with UV excitation, while the coordination compounds display photochromism with both excitation in the UV region and excitation into lower energy absorption bands characteristic of the coordination compounds, through which the excitation wavelengths for the photocyclization can be extended from λ≦340 nm to wavelengths beyond 470 nm. Switching of the luminescence properties of the compounds has also been achieved through photochromic reactions. | 2010-06-03 |
20100137597 | SYNTHESIS Of DIETHYLPHOSPHONATE - This application discloses a novel process for the preparation of phosphonate esters useful as intermediates in the preparation of himbacine analogs, themselves useful as thrombin receptor antagonists. The chemistry taught herein can be exemplified by the following scheme: | 2010-06-03 |
20100137598 | Process for Preparing Hydrocodone Using a Super Acid - The present disclosure generally relates to a process for converting a fused, tricyclic compound to a fused, tetracyclic compound that includes a furan ring therein. More particularly, the present disclosure related to a process for preparing a hydrocodone compound, or a compound structurally related thereto, and in particular (+)-hydrocodone, by subjecting a structurally corresponding sinomenine starting compound to a super acid-assisted furan ring closure reaction. | 2010-06-03 |
20100137599 | PROCESS FOR PREPARING 1,4-BUTANDIOL MONITRATE - The present invention relates to a process for the preparation of 1,4-butanediol mononitrate as intermediate for large scale preparation of high purity nitrooxybutyl ester of pharmaceutically active compounds. | 2010-06-03 |
20100137600 | Photogenerated reagents - This invention describes reagent precursors and methods for chemical and biochemical reactions. These reagent precursors that can be activated in solution upon irradiation to generate reagents required for the subsequent chemical reactions. Specifically, photogenerated reagents (PGR) are useful for controlling parallel combinatorial synthesis and various chemical and biochemical reactions. | 2010-06-03 |
20100137601 | THIAZOLYLIMIDAZOLE DERIVATIVES AN THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN - The present invention relates to thiazolylimidazole derivatives of the general formula (I) in which: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3; and R | 2010-06-03 |
20100137602 | PROCESS AND INTERMEDIATES FOR PREPARING ARZOXIFENE - The present invention provides for novel compounds of formula I wherein X is S or S(O); R | 2010-06-03 |
20100137603 | DIALKYLPHENYL COMPOUNDS HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY - This invention relates to compounds of formula I: | 2010-06-03 |
20100137604 | METHOD OF MAKING PIPERIDINE DERIVATIVES - The present invention relates to a process for the preparation of piperidine derivatives including sufentanil, and their pharmaceutically acceptable salts, such as the citrate salt | 2010-06-03 |
20100137605 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES - The present invention is directed to a process for preparing the piperidine derivative compound 4-[4-[4-hydroxydiphenylmethyl)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethylphenylacetic acid of formula | 2010-06-03 |
20100137606 | NOVEL COMPOUND HAVING BETA-SECRETASE INHIBITORY ACTIVITY - A novel compound represented by the formula (1) below which has β-secretase inhibitory activity, its pharmaceutically acceptable salt or a prodrug thereof. | 2010-06-03 |
20100137607 | BARIUM SALT OF BENZIMIDAZOLE DERIVATIVE - The invention relates to crystalline barium salt of (S)-omeprazole, which is (S)- | 2010-06-03 |
20100137608 | POLY-N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES AND N-HETEROCYCLIC CARBENE TRANSITION METAL COMPLEXES FOR CARBON-SULFUR AND CARBON-OXYGEN COUPLING REACTIONS - Methods for carbon-sulfur (C—S) or carbon-oxygen (C—O) coupling reactions are provided. The methods involve the use of a transition metal complex comprising a heterocyclic carbene ligand complexed with a transition metal. Transition metal complexes comprising a heterocyclic carbene ligand complexed with nickel are also provided. The nickel heterocylic carbene complexes may be used for C—S or C—O coupling reactions. | 2010-06-03 |
20100137609 | METHOD FOR PRODUCING PURIFIED AMMONIUM SALT OF FLUORINATED BIS-SULFONYLIMIDE - Methods for preparing an ammonium salt and a lithium salt of a fluorinated bis-sulfonylimide by a practical and efficient method with a high yield with a small number of steps. Further, a high purity ammonium salt of a fluorinated bis-sulfonylimide useful for the method for producing a lithium salt is provided. | 2010-06-03 |
20100137610 | Indole compound - The purpose of the present invention is to provide a glucokinase activator useful as a pharmaceutical agent such as an agent for the prophylaxis or treatment of diabetes, obesity and the like. | 2010-06-03 |
20100137611 | THIAZOLOTHIAZOLE DERIVATIVE - A thiazolothiazole derivative is represented by the following Formula (I). In Formula (I), each R | 2010-06-03 |
20100137612 | METHOD FOR PRODUCTION OF 3-HYDROXYPROPAN-1-ONE COMPOUND FOR PRODUCTION OF 2- PROPEN-1-ONE COMPOUND AND METHOD FOR PRODUCTION OF ISOXAZLINE COMPOUND - There is provided a novel intermediate for producing pesticides. A method for producing 1,3-bis(substituted phenyl)-3-substituted-3-hydroxypropan-1-one compound of Formula (3) comprises reacting an aromatic ketone compound of Formula (4) and a substituted acetophenone compound of Formula (5) as starting raw materials in an organic solvent or water in the presence or absence of an additive in the presence of a base in a suspended state. A method for producing 1,3-bis(substituted phenyl)-3-substituted-2-propen-2-one compound of Formula (2) comprises dehydrating the compound of Formula (3). A method for producing compound (2) in one step comprises reacting compound (4) and compound (5) to obtain compound (3). Further, a method for producing an isoxazoline compound of Formula (1) comprises reacting compound (2) and a hydroxylamine in an aliphatic or an aromatic hydrocarbon solvent which is optionally substituted by a halogen atom by adding an additive selected from a phase-transfer catalyst, a C | 2010-06-03 |
20100137613 | PROCESS FOR EPROSARTAN - The present invention provides an improved and commercially viable process for preparation of eprosartan and its pharmaceutically acceptable acid addition salts thereof in high purity and in high yield. Thus, for example, methyl 4-[[2-butyl-5-formyl-1 H-imidazol-1-yl]methyl]benzoate is reacted with ethyl 2-carboxy-3-(2-thienyl)propionate in the presence of a base, such as piperidine or piperidinium propionate in propionic acid, in cyclohexane solvent to give ethyl (αE)-α-[(2-n-butyl-1-[(4-(methoxy-carbonyl) phenyl]methyl]-1 H-imidazol-5-yl]methylene-2-thiophene propionate substantially free of decarboxylate impurity namely, ethyl 3-(2-thienyl)propionate, which is then subjected to base hydrolysis followed by treatment with methanesulfonic acid to obtain eprosartan mesylate in high purity and in high yield. | 2010-06-03 |
20100137614 | NEGATIVELY CHARGED MINOR GROOVE BINDERS - The present invention provides a negatively charged minor groove binding compound, oligonucleotide conjugates comprising the same, and methods for using the same. The negatively charged minor groove binding compounds of the present invention comprises an acidic moiety that is capable of being ionized under physiological conditions. In particular, the negatively charged minor groove binding compound of the present invention comprises a binding moiety that binds preferentially into a minor groove of a double, triple or higher stranded DNA, RNA, PNA or hybrids thereof. The binding moiety comprises at least one aryl moiety and an acidic moiety which is covalently attached to a phenyl portion of the aryl moiety or to a heteroatom of a heteroaryl portion of the aryl moiety. | 2010-06-03 |
20100137615 | Homogeneous Asymmetric Hydrogenation Process - Provide that a useful catalyst for homogeneous hydrogenation, particularly a catalyst for homogeneous asymmetric hydrogenation for hydrogenation, particularly asymmetric hydrogenation, which is obtainable with comparative ease and is excellent in economically and workability, and a process for producing a hydrogenated compound of an unsaturated compound, particularly an optically active compound using said catalyst with a high yield and optical purity. | 2010-06-03 |
20100137616 | INDOLE COMPOUNDS USEFUL AS SEROTONIN SELECTIVE AGENTS - Novel indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds. | 2010-06-03 |
20100137617 | METHOD FOR PRODUCING AROMATIC COMPOUND - Disclosed is a method for producing an aromatic compound represented by the general formula (2) below, which is characterized in that a compound represented by the general formula (1) below is reacted with a sulfur compound (at least one member selected from the group consisting of sulfur, hydrogen sulfide, metal hydrosulfides and metal sulfides) or a selenium compound. (In the formula (1), R | 2010-06-03 |
20100137618 | METHOD FOR SCREENING FOR COMPOUNDS SELECTIVELY INTERACTING WITH RAD9 - Natural and synthetic compounds of Formulae Ia-Ie having a lactone structure, in particular Securolide, have been determined to be effective anti-tumor compounds which target the hrad9 gene and/or protein encoded thereby or complex containing the protein and/or the p53 gene and/or protein. Securolide is cytoselective for mutants of hRad9 based on studies conducted in Rad9 mutant yeast strains. Securolide appears to interact with mutant hRad9 in cancer cells to produce DNA lesions which result in apoptosis. Studies have demonstrated that Securolide is useful for treating proliferation disorders such as melanoma, leukemia, breast cancer, lung cancer, ovarian cancer, colon cancer, esophagus cancer, liver cancer, and lymphatic cancer, and to alleviate pain associated with the cancer. Other compounds effective for the treatment of cancer and optionally pain associated therewith may also be identified using the same assays, for example, by screening for efficacy in assays using Rad9 and/or p53 defective mutant yeasts. | 2010-06-03 |
20100137619 | CRYSTALLINE POLYMORPHIC FORMS OF OLOPATADINE HYDROCHLORIDE AND PROCESSES FOR THEIR PREPARATION - The invention relates to new polymorphic forms of olopatadine hydrochloride, designated herein as olopatadine hydrochloride Forms A and B, and methods of preparing, purifying and treating them. | 2010-06-03 |
20100137620 | PROCESS FOR THE PREPARATION OF 1,4-DIALKYL-2,3-DIOL-1,4-BUTANEDIONE - The present invention relates to a process for the preparation of compounds of a 1,4-dialkyl-2,3-diol-1,4-butanedione by a acidic aldol condensation between an alkyl glyoxal and an α-hydroxy ketone. | 2010-06-03 |
20100137621 | PROCESS AND APPARATUS FOR REDUCING HEAVY BYPRODUCT FORMATION DURING DISTILLATION - A process and apparatus for recovering dichlorohydrins from a mixture comprising dichlorohydrins, water, one or more compounds selected from esters of dichlorohydrins, monochlorohydrins and/or esters thereof, and multihydroxylated-aliphatic hydrocarbon compounds and/or esters thereof, and optionally one or more substances comprising chlorinating agents, catalysts and/or esters of catalysts while minimizing formation of heavies is disclosed. | 2010-06-03 |
20100137622 | INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-- DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS - The present invention relates to a process for the synthesis of the known 17-acetoxy-11-β-[4-(dimethyl amino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione (further on CDB-4124) of formula (I) from 3,3-[1,2-ethandiyl-bis(oxy)]-oestr-5(10),9(11)-dien-17-one of formula (II). Compound CDB-4124 belongs to the group of anti-hormones. The process has the following steps: i) formation of an epoxide; ii) addition of hydrogen cyanide; iii) silylation of a hydroxyl group; iv) reaction with 4-(dimethylamino)-phenyl magnesium bromide Grignard reagent in the presence of CuCl (Teutsch reaction); v) silylation of a hydroxyl group with trimethyl chlorosilane; vi) reaction with diisobutyl aluminum hydride and after addition of acid to the reaction mixture; vii) methoxy-methylation with methoxy-methyl Grignard reagent formed in situ, while hydrolyzing the trimethylsilyl protective groups; viii) oxidation of a hydroxyl group with dicyclohexyl carbodiimide in the presence of dimethyl sulfoxide and a strong organic acid (Swern oxidation), and in given case after purification by chromatography; ix) acetylation of a hydroxyl group with acetic anhydride in the presence of perchloric acid, and in given case, purification by chromatography. The invention also relates to new intermediates of the process. | 2010-06-03 |
20100137623 | STABLE CATALYST PRECURSOR OF RH COMPLEX CATALYSTS - The present invention relates to the preparation and use of stable catalyst precursors of rhodium complex catalysts. | 2010-06-03 |
20100137624 | PROCESS FOR PREPARING DIALKYL OXIDE METALLOCENES OR DIARYL OXIDE METALLOCENES - Process for preparing bridged, stereorigid, stereomerically pure dialkoxide metallocenes, diaryl oxide metallocenes and preferably diphenoxide metallocenes of the general formula Q(Cp)(Cp′)M(OR | 2010-06-03 |
20100137625 | PROCESS FOR PREPARING 1,5-PENTANEDIOL AND/OR 1,6-HEXANEDIOL - An objective is to provide a process for preparing 1,5-pentanediol and/or 1,6-hexanediol comprising esterifying, with an alcohol such as methanol, ethanol, butanol or 1,6-hexanediol, a mixture of carboxylic acids such as glutaric acid, adipic acid and 6-hydroxycaproic acid which are a by-product in preparation of cyclohexanone by oxidation of cyclohexane with oxygen or an oxygen-containing gas; and hydrogenating the resulting esterified product in the presence of a copper-containing catalyst, which process is an industrially suitable process for preparing 1,5-pentanediol and/or 1,6-hexanediol in a high yield while controlling deterioration of the catalyst. The above objective is achieved by hydrogenating the esterified product with a catalyst obtained by prereducing a copper-containing catalyst in an alcohol having an acid value (AV) of 0.5 mg KOH/g or less or an ester having an acid value (AV) of 0.5 mg KOH/g or less. | 2010-06-03 |
20100137626 | ORGANIC SILANE COMPOUND FOR FORMING SI-CONTAINING FILM BY PLASMA CVD AND METHOD FOR FORMING SI-CONTAINING FILM - An organic silane compound for forming a Si-containing film by plasma CVD is provided. The silane compound contains 2 or more silicon atoms bonded by an intervening straight chain or branched oxygen-containing hydrocarbon chain having 4 to 8 carbon atoms containing a bond represented by C | 2010-06-03 |
20100137627 | 3-(2-Alkoxycarbonyloxy-Phenyl) Acrylic Acid Esters and Their Use as Precursors for the Delivery of Olfactory Compounds - A compound of formula (I), their use as precursors and a method of their production | 2010-06-03 |
20100137628 | PROCESS FOR THE SYNTHESIS OF (METHOXY-1-NAPHTHYL) ACETONITRILE AND APPLICATION IN THE SYNTHESIS OF AGOMELATINE - Process for the industrial synthesis of the compound of formula (I) | 2010-06-03 |
20100137629 | METHOD FOR THE CRYSTALLIZATION OF 2-(4-N,N-DIETHYL AMINO-2-HYDROXY BENZOYL)-BENZOIC ACID-N-HEXYL ESTER - The present invention relates to a method for the crystallization of n-hexyl 2-(4-N,N-diethylamino-2-hydroxybenzoyl)benzoate, to a method for the production of pourable or flowable particles of crystalline n-hexyl 2-(4-N,N-diethylamino-2-hydroxybenzoyl)benzoate and to specific pourable or flowable particles of crystalline n-hexyl 2-(4-N,N-diethylamino-2-hydroxybenzoyl)benzoate. | 2010-06-03 |
20100137630 | Manufacture of Purified Alcohols - Acetals are formed from an aldehyde hydrogenation product mixture comprising alcohols and at most | 2010-06-03 |
20100137631 | BATCH ESTERIFICATION - The efficiency of catalysed batch esterification reactions is improved by the use of a particular temperature and pressure profile during the reaction cycle. In particular elevated pressure is maintained to prevent alcohol boil off during initial mixing and reaction of the reactants prior to any catalyst addition, and preferably the pressure is reduced rapidly after the desired reaction temperature has been reached. | 2010-06-03 |
20100137632 | PROCESS FOR OSELTAMIVIR PHOSPHATE - The present invention provides an improved and commercially viable process for the preparation of oseltamivir phosphate. Thus, for example, ethyl (3R,4R,5S)-4-amino-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate is acetylated with acetic anhydride in methylene chloride in the presence of triethyl amine in the absence of water to give ethyl (3R,4R,5S)-4-(acetylamino)-5-azido-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate. | 2010-06-03 |
20100137633 | Process For Deacetalisation Of Alpha Aminoacetals - The invention relates to a process for the preparation of N-protected α-aminoaldehydes by deacetalization of the acetal functional group of corresponding N-protected α-aminoacetals using formic acid. | 2010-06-03 |
20100137634 | Hole jet reactor and a process for the preparation of an isocyanate using the reactor - The present invention relates to a hole-jetting type reactor and its applications, in particular to a process for the production of isocyanates by the phosgenation of aliphatic or aromatic diamines or triamines in the gas phase using this reactor. The present invention achieves a good mixing and reacting result of the gas-phase phosgenation reaction at a high temperature by improving the mixing of reactants in the reactor to reduce the possibility of forming swirls and eliminate negative pressure produced at a local jet area, which can finally reduce back-mixing and formation of solid by-products. | 2010-06-03 |
20100137635 | RADICAL SCAVENGER AND ACTIVE OXYGEN ELIMINATING AGENT - It is an object to provide a radical scavenger, an active oxygen-scavenging agent and the like, which are highly efficacious clinically and novel, and so as to attain the object, 3,4-dihydroxyphenylalanine derivatives such as N-β-alanyl-5-S-glutathionyl-1-3,4-dihydroxyphenylalanine (5-S-GAD) or pharmaceutically acceptable salts thereof are contained as an active ingredient. | 2010-06-03 |
20100137636 | IDENTIFICATION OF A NITRILASE FROM B. JAPONICUM BY RATIONAL GENOME MINING AND METHODS OF USE - The present disclosure relates to methods of rational genome mining. A method may include narrowing the number of clones that would otherwise need to be screened and/or identifying a gene with a desired catalytic activity. The disclosure also relates to a nitrile hydrolase from | 2010-06-03 |
20100137637 | CARBON-SUPPORTED GOLD CATALYST - The invention relates to processes for preparing supported gold catalysts on carbon supports, wherein the support is contacted with aqueous solution or suspension of a chloroauric acid precursor. The invention also relates to a carbon-supported gold catalyst and to the use thereof for oxidation of alcohols, aldehydes, polyhydroxy compounds and carbohydrates. | 2010-06-03 |
20100137638 | METHOD FOR PRODUCING ALPHA, BETA-UNSATURATED CALBOXYLIC ACID - Disclosed is a method for producing an α, β-unsaturated carboxylic acid from an olefin or an α, β-unsaturated aldehyde, while suppressing dissolution of a silica carrier, which is a carrier for a silica-supported noble metal-containing catalyst, in a water-containing solvent. Specifically disclosed is a method for producing an α, β-unsaturated carboxylic acid through oxidation of an olefin or an α, β-unsaturated aldehyde in a water-containing solvent in the presence of a silica-supported noble metal-containing catalyst in a reactor, in which at least one of silicic acid and ions thereof is supplied into the reactor. | 2010-06-03 |
20100137639 | PREPARATION OF ORGANIC COMPOUNDS FOR ENHANCED REACTIVITY - The present invention provides an improved method for preparing, purifying, precipitating, etc., a subject compound for use in a subsequent reaction carried out in suspension. The present invention relies on a precipitating solvent being added to an aqueous solution comprising the subject compound to form a precipitate of the subject compound, which may be further dried and/or purified. Compositions made according to present methods have improved characteristics and properties, such as increased surface and/or reduced density, resulting in a higher reactivity in a subsequent reaction carried out in suspension. | 2010-06-03 |
20100137640 | PRODUCTION OF PROPIONIC ACID - The invention relates to a method for obtaining propionic acid from the catalytic dehydration of glycerol, and to the propionic acid obtained by this method and using glycerol. | 2010-06-03 |
20100137641 | GENE INVOLVED IN QUORUM-SENSING SYSTEM OF ACETIC ACID BACTERIUM, ACETIC ACID BACTERIUM BRED BY MODIFICATION OF THE GENE AND METHOD FOR PRODUCTION OF VINEGAR BY USING THE ACETIC ACID BACTERIUM - The object of the present invention is to provide a method for efficiently producing vinegar that contains a higher concentration of acetic acid, wherein a gene involved in the acetic acid fermentation ability is obtained, the acetic acid fermentation ability of an acetic acid bacterium is improved by reducing or deleting the function of the protein encoded by the gene. An acetic acid bacterium with a remarkably improved acetic acid fermentation ability was obtained by obtaining genes encoding an acyl homoserine lactone synthase and an acyl homoserine lactone receptor-type transcription factor that are involved in the quorum-sensing system in the acetic acid bacterium, and modifying the genes so as to reduce or delete the function of the quorum-sensing system. Further provided is a method for more efficiently producing vinegar containing a higher concentration of acetic acid by using the acetic acid bacterium. | 2010-06-03 |
20100137642 | Low metal loaded, alumina supported, catalyst compositions and amination process - The present invention provides catalyst compositions useful for transamination reactions. The catalyst compositions have a catalyst support that includes transitional alumina, use a low metal loading (for example, less than 25 wt. %), and do not require the presence of rhenium. The catalyst compositions are able to advantageously promote transamination of a reactant product (such as the transamination of EDA to DETA) with excellent activity and selectivity, and similar to transaminations promoted using a precious metal-containing catalyst. | 2010-06-03 |
20100137643 | METHOD FOR SYNTHESIZING CYCLOHEXYL-SUBSTITUTED PHOSPHINES - The present invention relates to a process for preparing cyclohexyl-substituted phosphines. The invention further relates to a process for preparing cyclohexyl-substituted phosphine oxides which can be used as intermediates in the preparation of cyclohexyl-substituted phosphines. | 2010-06-03 |
20100137644 | Process for the preparation of trans-2,3-disubstituted naphthoquinones - The invention concerns a new process for the preparation of naphthoquinones, in particular an improved process for the preparation of 2,3-disubstituted 1,4-naphthoquinones, in the trans configuration. | 2010-06-03 |
20100137645 | Process for Decomposing Cyclohexylhydroperoxide - The present invention relates to a process for decomposing cyclohexylhydroperoxide into cyclohexanone, said process comprising mixing an organic feed solution comprising cyclohexylhydroperoxide with an aqueous base solution in the absence of a transition metal catalyst resulting in a mixture comprising (i) an aqueous phase and (ii) an organic phase comprising cyclohexanone and cyclohexanol. | 2010-06-03 |
20100137646 | PROCESS FOR THE PREPARATION OF XANTHOPHYLL CRYSTALS - The invention describes the preparation and isolation of xanthophylls from plant sources. whereby a transesterification process is utilized without the necessity of an aqueous format. | 2010-06-03 |
20100137647 | PRODUCTION OF GASOLINE FROM FERMENTABLE FEEDSTOCKS - Methods are disclosed for forming heptan-4-one, and, optionally, heptan-4-ol, from fermentable sugars. The sugars are fermented using a bacteria or yeast that predominantly forms butyric acid. The butyric acid is subjected to catalytic ketonization conditions to form heptan-4-one, with concomitant loss of water and carbon dioxide. The heptan-4-one can be subjected to catalytic hydrogenation to form heptan-4-ol, an either of these can be included in gasoline compositions. In one aspect, the fermentable sugars are derived from lignocellulosic materials such as wood products, switchgrass, or agricultural wastes, which are delignified to form lignin, cellulose and hemicellulose. The cellulose and hemicellulose can be depolymerized to form glycose and xylose, either or both of which can be fermented by the bacteria. Thus, the methods described herein can convert biomass to a fuel composition or fuel additive, which can be used in a conventional gasoline engine, unlike traditional fuels such as ethanol or biodiesel. | 2010-06-03 |
20100137648 | 6,8,10-UNDECATRIEN-3-ONE OR 6,8,10-UNDECATRIEN-4-ONE, AND AROMA COMPOSITIONS - This invention offers 6,8,10-undecatrien-3-one or 6,8,10-undecatrien-4-one which are represented by the following formula (1) | 2010-06-03 |
20100137649 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon - A process for preparing a detergent alcohol mixture comprising the steps of providing one or more poly-branched poly-olefins, wherein the poly-branched poly-olefins must contain one non-branched terminal olefin and one or more additional branched olefins in the molecule; hydroformylating said poly-branched poly-olefins to produce a poly-branched olefin containing aldehyde product with one or more olefins or mixture thereof; reducing the aldehyde product of step (b) in the presence of hydrogen and a hydrogenation catalyst to form a poly-branched detergent alcohol mixture; and removing said poly-branched alcohol mixture from said catalyst and branched aldehydes, alcohols and surfactants produced from the products of this process. | 2010-06-03 |
20100137650 | SHELL CATALYST, PROCESS FOR ITS PREPARATION AND USE - The present invention relates to a shell catalyst, a process for its preparation and also the use of the shell catalyst according to the invention. | 2010-06-03 |
20100137651 | METHOD FOR PRODUCTION OF A LIQUID COMPOSITION OF AN ORTHO-DIHYDROXYBENZYL COMPOUND OF HIGH PURITY AND SAID COMPOSITION - The invention relates to a process for the preparation of a liquid composition of an ortho-dihydroxybenzyl compound of high purity characterized in that it consists inpurifying the initial ortho-dihydroxybenzyl compound by distillation and recovering the condensed ortho-dihydroxybenzyl compound in an apparatus resistant to corrosion by the latter, and then mixing it with an organic solvent in a storage tank which is lined or made of a material which does not lead to metallic pollution. The invention also relates to a liquid composition of an ortho-dihydroxybenzyl compound of high purity comprising said compound and an organic solvent of said compound obtained according to said process. | 2010-06-03 |
20100137652 | MULTI-STAGE PROCESS AND APPARATUS FOR RECOVERING DICHLOROHYDRINS - A process and apparatus for recovering dichlorohydrins from a mixture comprising dichlorohydrins, one or more compounds selected from esters of dichlorohydrins, monochlorohydrins and/or esters thereof, and multihydroxylated-aliphatic hydrocarbon compounds and/or esters thereof, and optionally one or more substances comprising water, chlorinating agents, catalysts and/or esters of catalysts is disclosed. The mixture is distilled or fractionated to separate a lower boiling fraction comprising dichlorohydrin(s) from the mixture to form a higher boiling fraction comprising the residue of the distillation or fractionation. The higher boiling fraction is stripped to recover remaining dichlorohydrins. Advantages include more efficient recovery of dichlorohydrins for a given distillation column, less waste due to avoiding the conditions conducive to the formation of heavy byproducts, and reduced capital investment in recovery equipment. | 2010-06-03 |
20100137653 | PROCESS AND APPARATUS FOR RECOVERY OF DICHLOROHYDRINS VIA CODISTILLATION - A process and apparatus for recovering dichlorohydrins from a mixture comprising dichlorohydrins, one or more compounds selected from esters of dichlorohydrins, monochlorohydrins and/or esters thereof, and multihydroxylated-aliphatic hydrocarbon compounds and/or esters thereof, and optionally one or more substances comprising water, chlorinating agents, catalysts and/or esters of catalysts is disclosed. The mixture is stripped to recover dichlorohydrin(s) while distilling or fractionating the mixture to separate a lower boiling fraction comprising dichlorohydrin(s) from the mixture in one step. Advantages include more efficient recovery of dichlorohydrins for a given distillation column, less waste due to avoiding the conditions conducive to the formation of heavy byproducts, and reduced capital investment in recovery equipment. | 2010-06-03 |
20100137654 | Method for Converting Glycerol to Propanol - A method and apparatus for converting glycerol into propylene glycol by directing a basic glycerol containing feed and a hydrogen containing gas into a reaction zone including a fixed bed of catalyst that is operating at glycerol conversion conditions where the reactor includes and at least one quench zone and directing a quench material into the quench zone. | 2010-06-03 |
20100137655 | PROCESS FOR THE BIOLOGICAL PRODUCTION OF 1,3-PROPANEDIOL FROM GLYCEROL WITH HIGH YIELD - The present invention provides a method for the anaerobic production of 1,3 propanediol, by culturing a | 2010-06-03 |
20100137656 | METHOD FOR IMPROVING THE COLOR NUMBER OF TRIMETHYLOLPROPANE - The present invention relates to a method for the production of trimethylolpropane with a low color number by treatment with activated carbon. | 2010-06-03 |
20100137657 | COMBINED TEMPERATURE CONTROLLED WATER ADSORPTION AND TWO STAGE HEAT PUMP PROCESS FOR FUEL ETHANOL DEHYDRATION - Systems and processes for dehydration of a process stream in the production of motor fuel grade ethanol (MFGE) can include temperature controlled adsorption of water in the process stream, and heat pumping to transfer heat from the process stream to a heat sink using one or more stages of heat pumping. One stage of heat pumping can be achieved during the regeneration process of a temperature controlled adsorber by desorbing the adsorbed water at a thermal condition enabling useful heat recovery. Another stage of heat pumping can be achieved during the adsorption process of a temperature controlled adsorber by transferring the heat of water adsorption to a heat sink. The heat sink with respect to each stage of heat pumping can be a solids separation unit, such as a beer column. | 2010-06-03 |
20100137658 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUNDS - Provided is a process for making 2-chloro-1,1,1,2-tetrafluoropropane. The process has the step of hydrofluorinating 2-chloro-3,3,3-trifluoropropene in the presence of a catalyst selected from the group consisting of SbCl | 2010-06-03 |
20100137659 | PROCESS FOR THE SYNTHESIS OF 2,2',6-TRIBROMOBIPHENYL - A process for the synthesis of 2,2′,6-tribromobiphenyl. | 2010-06-03 |
20100137660 | PROCESS FOR THE CRYSTALLIZATION SEPARATION OF P-XYLENE - Provided is a process for crystallization separating p-xylene, comprising: a) feeding a mixed xylenes stream comprising greater than or equal to 60% by weight, of p-xylene, such as 60% to 98% by weight of p-xylene, to a crystallization unit to perform cooling crystallization, to obtain a slurry comprising p-xylene crystals; and b) feeding the slurry to a filtration and purification unit, to obtain a mother liquor, washings, and p-xylene, wherein the filtration and purification unit uses a simulated moving bed or a combination of multiple moving beds. | 2010-06-03 |
20100137661 | Production of High Purity Cumene From Non-Extracted Feed and Hydrocarbon Composition Useful Therein - A non-extracted hydrocarbon composition feed is substantially free of both C | 2010-06-03 |
20100137662 | Production of Diesel Fuel from Biorenewable Feedstocks Using Non-Flashing Quench Liquid - A process has been developed for producing diesel boiling range fuel from renewable feedstocks such as plant oils and animal oils, fats, and greases. The process involves treating a renewable feedstock by hydrogenating and deoxygenating to provide a hydrocarbon fraction useful as a diesel or aviation boiling range fuel or fuel blending component. If desired, the hydrocarbon fraction can be isomerized to improve cold flow properties. A portion of the hydrogenated and deoxygenated feedstock is used as a non-flashing liquid quench stream to control the temperature of the hydrogenation and deoxygenation reactor. | 2010-06-03 |
20100137663 | Combination of Hydrogenation and Base Catalyzed Depolymerization for Lignin Conversion - A process for the conversion of lignin to chemical precursors is presented. The process comprises treating the lignin to form less acidic compounds. The process includes reacting lignin with a hydrogenation catalyst under a hydrogen atmosphere to convert acidic oxygenate compounds to less acidic oxygenates or hydrocarbons. The oxygenate compounds are reacted in a dehydrogenation and deoxygenation process to remove the oxygen and to convert the cyclic hydrocarbons back to aromatic compounds. | 2010-06-03 |
20100137664 | PROCESS FOR 1,3-BUTADIENE SEPARATION FROM A CRUDE C4 STREAM WITH ACETYLENE CONVERTER - Disclosed is a method of recovering 1,3-butadiene from a C4 stream containing butane, isobutane, 2-butene, 1-butene, isobutene, butadiene and acetylene. The process of recovering highly pure 1,3-butadiene includes acetylene conversion for selectively converting acetylene through liquid-phase hydrogenation, so that the acetylene content is decreased to 70 wt ppm or less, and 1,3-butadiene extraction using an extractive distillation column, a pre-separator, a solvent stripping column, a solvent recovery column, and a purification column. Through the acetylene conversion, the concentration of vinylacetylene is decreased to 70 wt ppm or less, after which 1,3-butadiene is recovered using only one extractive distillation column, thereby considerably decreasing the degree of utility and the loss of streams in the course of extraction. The number of units necessary for the process is decreased, thus remarkably reducing the time during which impurities can accumulate in a processing unit. | 2010-06-03 |
20100137665 | Process for Lignin Conversion to Chemicals or Fuels with H2 Generated from Lignin Depolymerization Products - A process is presented for the production of high value chemicals from lignin. The process comprises combining several internal steps to use the hydrogen generated by the process, rather than adding an external source of hydrogen. The process can combine the decomposition of oxygenates formed during the deoxygenation process with hydrogenation of deoxygenated lignin compounds. | 2010-06-03 |
20100137666 | CATALYST FOR AROMATIZATION OF LOWER HYDROCARBONS AND PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS - A catalyst for aromatizing a lower hydrocarbon, in order to increase the amount of production of useful aromatic compounds, such as benzene and toluene, by improving the methane conversion rate, the benzene formation rate, the naphthalene formation rate and the BTX formation rate (or a total formation rate of benzene, toluene and xylene) is such that molybdenum and silver are loaded on a metallosilicate as a substrate. It is more preferable to obtain the aromatizing catalyst by loading molybdenum and silver after modifying a zeolite formed of the metallosilicate with a silane compound that has a molecular diameter larger than a pore diameter of the zeolite and that has an amino group, which selectively reacts at a Bronsted acid point of the zeolite, and a straight-chain hydrocarbon group. | 2010-06-03 |
20100137667 | Aromatic Isomerization Catalyst and Isomerization Process - One exemplary embodiment can be an extruded C8 alkylaromatic isomerization catalyst. The extruded catalyst can include:
| 2010-06-03 |
20100137668 | OLIGOMERIZATION PROCESS - A process for oligomerizing isoolefins, the process including: feeding an isoolefin to an oligomerization reaction zone; feeding an oxygen-containing reaction moderator to the oligomerization reaction zone; concurrently in the oligomerization reaction zone: contacting the isoolefin with an oligomerization catalyst to convert at least a portion of the isoolefin to oligomers comprising dimers and trimers of the isoolefin; reacting a portion of the moderator with a portion of at least one of the isoolefin and the oligomers to form an oxygenated oligomerization byproduct; recovering an effluent from the oligomerization reaction zone comprising the oligomers and the oxygenated oligomerization byproduct; fractionating at least a portion of the effluent to recover a fraction comprising the oxygenated oligomerization byproduct and the trimers and a fraction comprising the dimers. | 2010-06-03 |
20100137669 | ETHYLENE TETRAMERIZATION CATALYST SYSTEMS AND METHOD FOR PREPARING 1-OCTENE USING THE SAME - Disclosed herein is a method of preparing 1-octene at high activity and high selectivity while stably maintaining reaction activity by tetramerizing ethylene using a chromium-based catalyst system comprising a transition metal or a transition metal precursor, a cocatalyst, and a P—C—C—P backbone structure ligand represented by (R | 2010-06-03 |
20100137670 | PROCESS AND APPARATUS FOR INJECTING OXYGEN INTO A REACTION GAS FLOWING THROUGH A SYNTHESIS REACTOR - Synthesis reactor comprising an apparatus for injecting oxygen, which can be initially charged in pure form, as air, or mixed with inert gas or water vapor, into a reaction gas which can flow through the synthesis reactor which finds use, for example, in an oxydehydrogenation plant, wherein oxygen and reaction gas have different temperatures, wherein a distribution element is provided upstream of the device for accommodating a catalyst charge in flow direction of the reaction gas, said distributor element comprising a distributor body, two tube plates and a multitude of gas guide tubes for passing the reaction gas through, and the oxygen can be supplied to the chamber between the gas guide tubes, wherein at least one baffle plate is arranged orthogonally to the gas guide tubes and divides the intermediate space into at least two distributor chambers, wherein the distributor chambers are connected to one another or merge into one another fluidically through one or more orifices, at least one gas line leads into the first distributor space in flow direction, through which the oxygen can be supplied, and the lower tube plate is provided in flow direction with a multitude of orifices in the form of nozzles, bores or the like, through which the oxygen can leave the intermediate space, wherein a solids-free gas mixing zone is provided below the lower tube plate. | 2010-06-03 |
20100137671 | METHOD FOR TREATING SPENT POT LINER - The present invention relates to a method for treating spent pot liner material (SPL) containing carbon and/or an inorganic material, the method comprising: providing a plasma furnace having first and second electrodes for generating plasma and a crucible having a non-electrically conductive inner surface, heating the SPL material in the crucible in the presence of a flux material and an oxidant by passing an arc between the first and second electrodes via the SPL material to form a molten slag material and convert at least some of the carbon in the SPL material to CO and/or CO2 and/or incorporate at least some of the inorganic material into the molten slag material. | 2010-06-03 |
20100137672 | DEGRADATION OF PHOSPHATE ESTERS BY MOLYBDOCENE AND TUNGSTOCENE DERIVATIVES - Degradation of phosphate esters, particularly neurotoxins and pesticides, is performed using metallocene derivatives, more particularly molybdocene and tungstocene derivatives. A metallocene derivative is hydrolyzed and then reacted with a phosphate ester. The preferred metallocene derivatives are molybdocene and tungstocene derivatives. The phosphate esters can include, but are not limited to, VX, VE, VG, VM, GB, GD, GA, GF, parathion, paraoxon, triazophos, oxydemeton-methyl, chlorpyrifos, fenitrothion and pirimiphos-methyl, representing both chemical warfare agents as well as pesticides and insecticides. | 2010-06-03 |
20100137673 | DOSIMETRY IMPLANT FOR TREATING RESTENOSIS AND HYPERPLASIA - The present invention discloses a method of selectively providing radiation dosimetry to a subject in need of such treatment. The radiation is applied by an implant comprising a body member and | 2010-06-03 |
20100137674 | BRACHYTHERAPY TREATMENT OF THE SPINE WITH IRRADIATED IMPLANTS - A spinal implant configured to facilitate focused treatment of spinal tumors includes a plurality of irradiated implant seeds configured to concentrate the dosage and duration of radiation treatment of tumors. | 2010-06-03 |
20100137675 | BONE CONDUCTION DEVICES GENERATING TANGENTIALLY-DIRECTED MECHANICAL FORCE USING A ROTATIONALLY MOVING MASS - A bone conduction device, comprising: a sound input element configured to receive an acoustic sound signal; an electronics module configured generate an electrical signal representing said acoustic sound signal; and a transducer, comprising a mass configured to move in a rotational direction, configured to generate a vibrational force in a tangential direction with respect to a recipient's bone. | 2010-06-03 |
20100137676 | N-ACETYLCYSTEINE AMIDE (NAC AMIDE) FOR TREATMENT OF OXIDATIVE STRESS ASSOCIATED WITH INFERTILITY - An in vitro culture and/or fertilization medium containing N-acetylcysteine amide (NAC amide) reduces or prevents oxidative stress and free radical formation that contribute to the cellular damage and eventual demise of sperm, oocytes and embryos that are cultured, fertilized and maintained in vitro. The NAC amide-containing medium composition for in vitro culture and fertilization is suitable for use in the culture of oocytes, in the culture and development of early embryos, in the preparation or culture of sperm, and in the pre-treatment of oocytes or sperm. The NAC amide-containing composition supports the growth of viable embryos until blastocyst stage. | 2010-06-03 |
20100137677 | METHOD FOR TREATMENT AND PREVENTION OF PARASTOMAL HERNIAS - A method and device for preventing or treating parastomal hernia is provided. The method can include positioning a graft material between a rectus sheath and a rectus abdominus muscle surrounding a stoma. | 2010-06-03 |
20100137678 | SELF-ADJUSTING ATTACHMENT STRUCTURE FOR A CARDIAC SUPPORT DEVICE - A cardiac support device including a jacket and elastic attachment structure for self-securing the jacket to a heart. The attachment structures can include undulating metal and polymer elements, a silicone band and elastomeric filaments on a base end of the jacket. | 2010-06-03 |
20100137679 | MINIMALLY INVASIVE BREAST LIFT METHOD WITH A SUPERIOR TISSUE SUPPORT AND AN INFERIOR ANCHOR - Described are methods and apparatus for use in supporting tissue in a patient's body. In some embodiments, the patient's breast or another tissue is supported. One method involves introducing a superior soft tissue anchor into a patient, the anchor having an inferiorly facing total surface area; and introducing at least one inferior soft tissue anchor into the patient, such that the at least one inferior soft tissue anchor is suspended from the superior soft tissue anchor, the sum of all of the at least one inferior soft tissue anchors having a superiorly facing total surface area. The inferiorly facing total surface area of the superior anchor can be greater, such as at least two times greater than the superiorly facing total surface area of the at least one inferior anchor. | 2010-06-03 |
20100137680 | MEDICAL MANIPULATOR DEVICE AND ACTUATOR SUITABLE THEREFOR - A clean and inexpensive medical manipulator device can be provided in which a risk of failure caused by current leakage or disconnection is eliminated and reliability is higher than in a manipulator device using an electrically driven actuator or electric motor. The medical manipulator device includes a stage section | 2010-06-03 |
20100137681 | ENDOSCOPIC INSTRUMENT MANAGEMENT SYSTEM - Endoscopic instrument management systems are described herein which allow one or more operators to manage multiple different instruments utilized in endoscopic procedures. In one aspect, responsibility for instrumentation management between one or more operators may be configured such that a first set of instruments is controlled by a primary operator and a second set of instruments is controlled by a secondary operator. The division of instrumentation may be facilitated by the use of separated instrumentation platforms or a single platform which separates each instrument for use by the primary operator. Such platforms may be configured as trays, instrument support arms, multi-instrument channels, as well as rigidized portions of instruments to facilitate its handling, among others. In another aspect, one or more plastically deformable instrument manifolds are provided to guide flexible endoscopic instruments into and through an endoscopic access device. | 2010-06-03 |
20100137682 | ENDOSCOPE - There is provided an endoscope capable of observing cells at a desired position existing in the depth direction with a simple structure as compared to the conventional configuration. The endoscope includes an insert unit to be inserted into a biological body, a low-scaling observation system for observing an observation position in a biological body with a low scaling, and a high-scaling observation system for observing a target position of the aforementioned observation position as a local position with a high scaling. The high-scaling observation system includes a plurality of illumination units for applying illumination light for high-scaling observation of the target position. The illumination units are arranged at predetermined positions of the end face of the insert unit. | 2010-06-03 |
20100137683 | CAPSULE-TYPE ENDOSCOPE HAVING SENSOR AND COMMUNICATION METHOD THEREOF - Disclosed is a capsule-type endoscope, including: a lens for obtaining an image inside the body, one or more sensors for obtaining information related to the inside of the body, a controller for interleaving the information detected by the one or more sensors with the image captured by the lens and encoding the image interleaved with the sensor data for signal output, and a transmitter for transmitting a signal from the controller. | 2010-06-03 |
20100137684 | ENDOSCOPE SYSTEM WITH SCANNING FUNCTION - An endoscope system has an optical fiber configured to transmit illumination light emitted from a light source to the tip portion of a scope; a scanner configured to spirally scan a target area with illumination light by vibrating the tip portion of said optical fiber; and an image generator configured to generate image data from image-pixel signals obtained from the light reflected from the target area. Then, the scanner scans the illumination light in a circular motion midway through a spiral scanning procedure. | 2010-06-03 |
20100137685 | DEVIATED VIEWING RIGID VIDEOENDOSCOPE WITH ADJUSTABLE FOCUSING - The disclosure relates to a deviated viewing rigid videoendoscopic probe with adjustable focusing, comprising a rigid inspection tube and a control handle attached to the inspection tube, the inspection tube having a longitudinal axis and a distal part comprising an image capture device having a viewing axis different from the longitudinal axis, the control handle comprising a rotation control device for making the viewing axis turn around the longitudinal axis, and a focusing control device of the image capture device for longitudinally moving in the inspection tube a part of the image capture device, the rotation control device and the focusing control device being respectively configured to make the viewing axis turn and focus the image capture device, independently from one another. | 2010-06-03 |