22nd week of 2013 patent applcation highlights part 48 |
Patent application number | Title | Published |
20130137827 | Process for Polymerizing Olefin-Based Polymers Containing High Molecular Weight Fractions in Condensed and Super-Condensed Mode - A process for producing an olefin-based polymer in a polymerization reactor including a fluidized bed, a disengaging section and a neck connecting the bed and disengaging section, at least one monomer, in the gas phase, in the presence of at least one catalyst containing at least two transition metals, one of the at least two transition metals being Ti, at least one cocatalyst, a composition having at least one compound selected from formula (I), and/or at least one compound selected from formula (II): (R1CO | 2013-05-30 |
20130137828 | POLYETHYLENE COMPOSITIONS, METHODS OF MAKING THE SAME, AND ARTICLES PREPARED THEREFROM - The invention is related to compositions suitable for the fabrication of pipes, and other articles, with excellent performance properties. The invention provides a composition, comprising a blend, wherein said blend comprises a high molecular weight ethylene-based interpolymer and a low molecular weight ethylene-based interpolymer, and the high molecular weight ethylene-based interpolymer is a heterogeneously branched linear or a homogeneously branched linear ethylene-based interpolymer, and has a density from 0.922 g/cc to 0.929 g/cc, and a high load melt index (I21) from 0.2 g/10 min to 1.0 g/10 min, and the low molecular weight ethylene-based interpolymer is heterogeneously branched linear or a homogeneously branched linear ethylene-based interpolymer, and has a density from 0.940 g/cc to 0.955 g/cc, and a melt index (I2) from 6 g/10 min to 50 g/10 min. The blend has a single peak in an ATREF profile eluting above 30° C., and has a coefficient of viscosity average molecular weight (CMv) less than −0.0032 in the log (calculated Mv) versus elution temperature, said CMv calculated in the range of elution temperatures from 70° C. to 90° C. The Mv is the viscosity average molecular weight. | 2013-05-30 |
20130137829 | Functionalization of Vinyl Terminated Polymers by Ring Opening Cross Metathesis - This invention relates to a polymer of a cyclic olefin and a vinyl terminated macromonomer, and processes for the production thereof. | 2013-05-30 |
20130137830 | Functionalized High Vinyl Terminated Propylene Based Oligomers - This invention relates to a functionalized co-oligomer having an Mn of 300 to 30,000 g/mol comprising 10 to 90 mol % propylene and 10 to 90 mol % of ethylene, wherein the oligomer has at least X % allyl chain ends, where: 1) X=(−0.94 (mole % ethylene incorporated)+100), when 10 to 60 mole % ethylene is present in the co-oligomer, and 2) X=45, when greater than 60 and less than 70 mole % ethylene is present in the co-oligomer, and 3) X=(1.83*(mole % ethylene incorporated)−83), when 70 to 90 mole % ethylene is present in the co-oligomer. This invention also relates to a functionalized homo-oligomer, comprising propylene, wherein the oligomer has: at least 93% allyl chain ends, an Mn of about 500 to about 20,000 g/mol, an isobutyl chain end to allylic vinyl group ratio of 0.8:1 to 1.2:1.0, and less than 100 ppm aluminum. This invention also relates to a process of making functionalized homo- or co-oligomer, comprising propylene, wherein the productivity is greater than 4500 g/mmol Hf (or Zr)/hour. | 2013-05-30 |
20130137831 | OPTIMIZED DRUG CONJUGATES - The invention generally relates to optimized drug conjugates. | 2013-05-30 |
20130137832 | COMMON SOLVENT PROCESS FOR PRODUCING HIGH MOLECULAR WEIGHT HALOGENATED RUBBER - The invention relates to an energy efficient, environmentally favourable process for the preparation of halogenated rubbers, in particular chloro- and bromobutyl rubber, that uses a common aliphatic medium of specific composition for both solution polymerization and subsequent halogenation of the rubber. More particularly, the invention relates to a process that employs a common aliphatic medium for both solution polymerization and halogenation of rubber with intermediate removal of un-reacted monomers. | 2013-05-30 |
20130137833 | RESIN COMPOSITION FOR SOLAR CELL ENCAPSULANT, AND SOLAR CELL ENCAPSULANT AND SOLAR CELL MODULE USING THE SAME - A resin composition for a solar cell encapsulant containing an ethylene.α-olefin copolymer and an organic peroxide or a silane coupling agent or the like, and having superior heat resistance, transparency, flexibility and adhesion property to a glass substrate, as well as good balance between rigidity and cross-linking efficiency, the solar cell encapsulant and a solar cell module using the same. | 2013-05-30 |
20130137834 | MODIFICATION OF PROPYLENE POLYMERS - The invention relates to a process for increasing the melt flow index of a propylene polymer, the process comprising melt mixing the propylene polymer in the presence of aqueous hydrogen peroxide. | 2013-05-30 |
20130137835 | Preparation of Polyphosphazene Microspheres - Methods of producing polyphosphazene microspheres comprising admixing aqueous solutions of a water-soluble polyphosphazene and an organic amine, or salt thereof, are disclosed. | 2013-05-30 |
20130137836 | Methods for Removing Polymer Skins from Reactor Walls - Methods for removing polymer skins or build-up from reactor walls in polymerization reactor systems containing a loop slurry reactor are disclosed. Such methods can employ removing some or all of the comonomer from the reactor system in combination with increasing the polymerization temperature of the loop slurry reactor. | 2013-05-30 |
20130137837 | ETHYLENE COPOLYMER WITH IMPROVED IMPACT RESISTANCE - Provided are ethylene copolymers with excellent impact resistance. More specifically, provided are ethylene copolymers satisfying certain correlation between the falling dart impact strength (F) or high rate impact resistant breakage energy (E) and Vicat softening point. The ethylene copolymers with improved impact properties are applicable to film, injection, compound, sheet, roto, pipe or blow molding. | 2013-05-30 |
20130137838 | NICKEL-BASED CATALYST COMPOSITION - In general the present invention provides a process for forming conjugated diene polymer, the process comprising the step of polymerizing conjugated diene monomer in the presence of a catalytically effective amount of a catalyst composition formed by combining (a) a nickel-containing compound, (b) an alkylating agent, (c) a fluorine-containing compound, (d) a carboxylic acid, and (e) an alcohol. | 2013-05-30 |
20130137839 | Long Chain Branched Polymers and Methods of Making Same - A polymer having a long chain branching content peaking at greater than about 20 long chain branches per million carbon atoms, and a polydispersity index of greater than about 10 wherein the long chain branching decreases to approximately zero at the higher molecular weight portion of the molecular weight distribution. A polymer having a long chain branching content peaking at greater than about 8 long chain branches per million carbon atoms, a polydispersity index of greater than about 20 wherein the long chain branching decreases to approximately zero at the higher molecular weight portion of the molecular weight distribution. A polymer having a long chain branching content peaking at greater than about 1 long chain branches per chain, and a polydispersity index of greater than about 10 wherein the long chain branching decreases to approximately zero at the higher molecular weight portion of the molecular weight distribution. | 2013-05-30 |
20130137840 | Processes of Controlling Molecular Weight Distribution in Ethylene/Alpha-Olefin Compositions - The present invention relates to compositions and processes of making ethylene/α-olefins. More particularly, the invention relates to processes of producing ethylene/α-olefin compositions having a controlled molecular weight distribution. The molecular weight distribution is controlled, for example, by controlling the relative monomer concentrations during contact with a pre-catalyst and/or using a catalyst comprising a catalytic amount of a molecule having the structure: | 2013-05-30 |
20130137841 | SELF-ASSEMBLED MULTI-NUCLEAR CATALYST FOR OLEFIN POLYMERIZATION - A self-assembled olefin polymerization catalyst comprising a transition metal complex according to formula (I) A-[(L | 2013-05-30 |
20130137842 | ORGANIC SEMICONDUCTOR COMPOUND, AND ORGANIC THIN FILM INCLUDING THE ORGANIC SEMICONDUCTOR COMPOUND - An organic semiconductor compound may be represented by the above Chemical Formula 1 or Chemical Formula 2, and an organic thin film may include the organic semiconductor compound according to Chemical Formula 1 or 2. | 2013-05-30 |
20130137843 | POLYPROPYLENE GRIDS MANUFACTURED WITH A BETA NUCLEATION ADDITIVE, THE METHOD OF MANUFACTURE AND USES THEREOF - Integral polymer grids, such as geogrids, are made by stretching and orienting a polypropylene starting sheet material having a defined pattern of holes or depressions in which the polypropylene is at least 50%, and preferably up to about 80%, beta crystals caused by adding a beta nucleating agent to the polypropylene, preferably in concentrations between about 10 ppm to about 100 ppm. Such beta nucleated polypropylene grids exhibit increased yield and break tensile strengths, increased 2% and 5% tensile strengths, increased modulus characteristics, increased torsional stiffness, increased impact strength, and increased grid junction strength. Methods for manufacturing the beta nucleated polypropylene mesh grids are disclosed, along with applications for stabilizing particulate material in civil engineering structures, and the like. | 2013-05-30 |
20130137844 | Polymerizable Silicone Copolyol Macromers And Polymers Made Therefrom - A polymerizable dimethicone copolyol macromer composition is synthesized by reacting itaconic anhydride with a dimethicone copolyol. During the reaction itaconic anhydride spontaneously isomerizes to citraconic anhydride which in turn is esterified by the dimethicone copolyol. The obtained macromers are copolymerizable with olefinically unsaturated monomers. Polymers containing the macromer repeating units are useful in a variety of applications including personal care, textile and industrial formulations to deliver softness, lubricity, fixative, water repellency, gloss, surface modification, and surfactant properties. | 2013-05-30 |
20130137845 | PRODUCTION METHOD FOR A WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER RESIN, A WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER RESIN PRODUCED BY MEANS OF THE METHOD, AND A COMPOUND OF THE WHOLLY AROMATIC LIQUID CRYSTALLINE POLYESTER RESIN - Disclosed are a production method for a wholly aromatic liquid crystalline polyester resin, a wholly aromatic liquid crystalline polyester resin produced using the method, and a compound of the wholly aromatic liquid crystalline polyester resin. The disclosed production method for a wholly aromatic liquid crystalline polyester resin comprises the steps of synthesizing a wholly aromatic liquid crystalline polyester resin by synthesizing a wholly aromatic liquid crystalline polyester prepolymer by a condensation polymerization of a monomer and then reducing the pressure inside a reaction vessel containing the synthesized prepolymer at a predetermined internal pressure reduction rate of the reaction vessel. | 2013-05-30 |
20130137846 | POLYIMIDE FIBER WITH HIGH STRENGTH AND HIGH MODULUS AND ITS PREPARATION METHOD - A high-strength high-modulus polyimide fiber and its preparation method pertain to the technical field of high-performance organic fiber. This fiber includes the polyimide (PI) fiber made from 3,3′,4,4′-biphenyl tetracarboxylic diandhydride (BPDA), p-phenylenediamine (pPDA) and 2-(4-aminophenyl)-1H-benzimidazol-5-amine (BIA), wherein the molar ratio between PPDA and BIA is 1:10˜3:1. During the synthesis, other diamine and diandhydride monomers may also be added. In the preparation process, the gradient temperature reaction method and one-step continuous preparation method are adopted, the synthesis and processing difficulty caused by the increase of the content of BIA is overcome, the problem of poor uniformity and stability of fiber is solved and PI fiber with high strength and high modulus is obtained. Its strength may reach 4.5 GPa and modulus may reach 201 GPa. Moreover, the sources of the raw materials are extensive, the spinning process is continuous, the cost is low, the efficiency is high and industrial production may be realized. | 2013-05-30 |
20130137847 | POLY(DIHYDROFERULIC ACID) A BIORENEWABLE POLYETHYLENE TEREPHTHALATE MIMIC DERIVED FROM LIGNIN AND ACETIC ACID AND COPOLYMERS THEREOF - An embodiment of the invention is directed to a biorenewable thermoplastic, poly(dihydroferulic acid) (PHFA), which is an effective polyethylene terephthalate (PET) mimic. In another embodiment of the invention, a biorenewable thermoplastic copolymer, poly(dihydroferulic acid-co-ferulic acid) is an effective polystyrene mimic. The PHFA and the copolymer can be prepared by the homocondensation of acetyldihydroferulic acid or the copolymerization of acetyldihydroferulic acid with acetylferulic acid, which are monomers that can be synthesized from starting materials isolated from lignin, rice bran, or other biorenewable sources. | 2013-05-30 |
20130137848 | ORGANIC SEMICONDUCTOR COMPOUND, ORGANIC THIN FILM INCLUDING THE ORGANIC SEMICONDUCTOR COMPOUND AND ELECTRONIC DEVICE INCLUDING THE ORGANIC THIN FILM, AND METHOD OF MANUFACTURING THE ORGANIC THIN FILM - An organic semiconductor compound may include a structural unit represented by the aforementioned Chemical Formula 1 and an organic thin film and an electronic device may include the organic semiconductor compound. | 2013-05-30 |
20130137849 | DIPEPTIDE LINKED MEDICINAL AGENTS - A non-enzymatically self cleaving dipeptide element is provided that can be linked to known medicinal agents via an amide bond. The dipeptide will spontaneously be cleaved from the medicinal agent under physiological conditions through a reaction driven by chemical instability. Accordingly, the dipeptide element provides a means of linking various compounds to known medicinal agents wherein the compounds are subsequently released from the medicinal agent after a predetermined time of exposure to physiological conditions. For example, the dipeptide can be linked to an active site of a drug to form a prodrug and/or the dipeptide may comprise a depot polymer to sequester an injectable composition comprising the complex at the point of administration. | 2013-05-30 |
20130137850 | NOVEL POLYMER AND PROCESS FOR PRODUCING THE SAME - An objective of the invention is to provide an excellent biomaterial having a good operability and a high safety; the solution is a polymer having one or more peptide units represented by formula (1) as described below and one or more saccharide residues derived from polysaccharides: | 2013-05-30 |
20130137851 | TARGETED DELIVERY OF ANTIMICROBIAL AGENTS - A cationic antimicrobial peptide (CAMP) conjugate is disclosed. The CAMP conjugate may be made by identifying a suitable carrier peptide; identifying a suitable antimicrobial agent; creating a conjugate by conjugating the peptide with the antimicrobial agent; and evaluating and refining the conjugate. The peptide may be short peptide based on the sequence of a CAMP, such as human β-defensin-3. The peptide can be directly connected to the antimicrobial agent or through a linker segment. The antimicrobial agent may be connected to the peptide or the linker segment through stable or cleavable bonding. The peptide may carry and facilitate the delivery of the conjugated antimicrobial agent to a microbe. | 2013-05-30 |
20130137852 | NOVEL COMPOUNDS AS DPP-IV INHIBITORS AND PROCESS FOR PREPARATION THEREOF - The present invention relates to process for preparation of novel compounds which are acting as inhibitors of dipeptidyl peptidase-IV enzyme and is depicted by the structural formula as given below: Formula VI. Which are useful in the treatment or prevention of diseases in which the dipeptidylpeptidase-IV enzyme is involved, such as diabetes and particularly type-2 diabetes. | 2013-05-30 |
20130137853 | METHOD FOR PRODUCING PEPTIDE - Peptides may be produced by using (A) a first amino acid or peptide, which is converted into its ionic liquid form through the formation of an ionic bond, as a substance serving as both a reaction solvent and a reaction starting material; and reacting the first amino acid or peptide with (B) an ester of second amino acid or peptide, in the absence of any peptide hydrolase or any condensation agent, in the presence of water in an amount of not more than 20% by mass relative to the total mass of the reaction system to form a peptide bond between the first amino acid or peptide and the second amino acid or peptide. By means of this process, it is possible to synthesize a peptide at a high concentration and at a high yield, and this method is excellent for producing peptides on an industrial scale. | 2013-05-30 |
20130137854 | COLLAGEN MIXTURE AND METHOD OF MAKING THE SAME - A collagen mixture having a portion of unhydrolyzed eggshell membrane collagen and Avian collagen. | 2013-05-30 |
20130137855 | HUMANIZED ANTI-INTERLEUKIN 3 RECEPTOR ALPHA CHAIN ANTIBODIES - The present disclosure provides antibodies that bind to interleukin-3 receptor alpha chain and uses thereof. | 2013-05-30 |
20130137856 | PROTEIN BINDING DOMAINS STABILIZING FUNCTIONAL CONFORMATIONAL STATES OF GPCRS AND USES THEREOF - The present invention relates to the field of GPCR structure biology and signaling. In particular, the present invention relates to protein binding domains directed against or capable of specifically binding to a functional conformational state of a G-protein-coupled receptor (GPCR). More specifically, the present invention provides protein binding domains that are capable of increasing the stability of a functional conformational state of a GPCR, in particular, increasing the stability of a GPCR in its active conformational state. The protein binding domains of the present invention can be used as a tool for the structural and functional characterization of G-protein-coupled receptors bound to various natural and synthetic ligands, as well as for screening and drug discovery efforts targeting GPCRs. Moreover, the invention also encompasses the diagnostic, prognostic and therapeutic usefulness of these protein binding domains for GPCR-related diseases. | 2013-05-30 |
20130137857 | TRANSGLYCOSYLATION ACTIVITY OF GLYCOSYNTHASE MUTANTS OF AN ENDO-BETA-N-ACETYLGLUCOSAMINIDASE (ENDO-D) FROM STREPTOCOCCUS PNEUMONIAE - The present invention provides for recombinant Endo-D and selected mutants that exhibit reduced hydrolysis activity and increased transglycosylation activity for the synthesis of glycoproteins wherein a desired sugar chain is added to a core fucosylated or nonfucosylated GlcNAc-protein acceptor by transglycosylation. Such recombinant Endo-D and selected mutants are useful for efficient glycosylation remodeling of IgG1-Fc domain. | 2013-05-30 |
20130137858 | IMMOBILIZED PROTEINS AND METHODS AND USES THEREOF - The invention relates to the field of covalently attaching proteins to a substrate, particularly to methods of immobilizing proteins by posttranslationally modifying a cysteine residue of said protein through the addition of functional groups. The invention also relates to biological molecules used in such techniques, including proteins, and detection methods and kits that utilize such immobilized proteins, such as a microdevice or “protein chip”, a high-throughput screening device, and for the microscopy of proteins on a surface. | 2013-05-30 |
20130137859 | METHODS OF CRYSTALLISING PERFORIN - A method for isolating crystals of perforin including the step of: crystallising perforin from solution at pH 6.4 to 8.0 and 20±5° C. | 2013-05-30 |
20130137860 | Purification Of Proteins - The present invention relates to a selectively soluble polymer capable of binding to a desired biomolecules in a mixture containing various biological materials and the methods of using such a polymer to purify a biomolecule from such a mixture. The polymer is soluble in the mixture under a certain set of process conditions such as pH or temperature and/or salt concentration and is rendered insoluble and precipitates out of solution upon a change in the process conditions. The polymer is capable of binding to the desired biomolecule (protein, polypeptide, etc) and remains capable of binding to that biomolecule even after the polymer is precipitated out of solution. The precipitate can then be filtered out from the remainder of the stream and the desired biomolecule is recovered such as by elution and further processed. | 2013-05-30 |
20130137861 | NOVEL METHODS FOR THE SYNTHESIS AND PURIFICATION OF OLIGOMERS - A reagent for oligonucleotide synthesis or purification, wherein the reagent has a structure of: | 2013-05-30 |
20130137862 | CELLULOSE CROSSLINKED FIBERS MANUFACTURED FROM PLASMA TREATED PULP - Intrafiber crosslinked cellulose pulp fibers manufactured from a plasma-treated pulp sheet are provided. The provided fibers have lower knot content and increased wet bulk compared to an untreated pulp sheet. Methods for forming the fibers are also provided. | 2013-05-30 |
20130137863 | Preparation of caprolactone, caprolactam, 2,5-tetrahydrofuran-dimethanol, 1,6-hexanediol or 1,2,6-hexanetriol from 5-hydroxymethyl-2-furfuraldehyde - The present invention relates to a method for preparing caprolactone, comprising converting 5-hydroxymethyl-2-furfuraldehyde by hydrogenation into at least one intermediate compound selected from the group of 2,5-tetrahydrofuran-dimethanol, 1,6-hexanediol and 1,2,6-hexanetriol,and preparing caprolactone from said intermediate compound. | 2013-05-30 |
20130137864 | PROCESS FOR THE PREPARATION OF LINEZOLID - The present invention provides an improved process for the preparation of Linezolid of formula (D. The present invention relates to preparation of intermediate (R)—N-[[3-[3-fluoro-4-morpholinyl]phenyl|-2-oxo-5-oxazolidinyl]methanol of formula (II), Linezolid amine of formula (Ia) and their use in the preparation of Linezolid. The present invention further provides process for the preparation of Form I of Linezolid of formula (I). | 2013-05-30 |
20130137865 | HETEROARYL-PYRAZOLE DERIVATIVE - A compound represented by formula [I] and a pharmaceutically accepted salt of said compound are a novel compound and a pharmaceutically accepted salt thereof which exert antagonistic activity against group II metabotropic glutamate (mGlu) receptors, and are effective as a novel preventive or therapeutic agent for disorders such as mood disorders (depressive disorder, bipolar disorder, etc.), anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, posttraumatic stress disorder, a specific phobic disorder, acute stress disorder, etc.), schizophrenia, Alzheimer's disease, cognitive impairment, dementia, drug dependence, convulsions, shivering, pain, sleep disorders, and the like. | 2013-05-30 |
20130137866 | Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device - As a novel substance having a novel skeleton, a novel organometallic complex that can emit phosphorescence in the green to red wavelength region and has high emission efficiency and a high yield of synthesis is provided. One embodiment of the present invention is an organometallic complex in which a diketone having a five-membered or six-membered alicyclic structure composed of carbon and hydrogen is a ligand. | 2013-05-30 |
20130137867 | NOVEL CRYSTAL OF ERLOTINIB BASE AND THE PREPARATION METHOD THEREOF - A novel crystal of antitumor drug erlotinib base and its preparation method are provided in the present invention. A preparation method of erlotinib hydrochloride with high-purity is also provided in the present invention. | 2013-05-30 |
20130137868 | SALTS OF RALTEGRAVIR - The present invention provides novel salts of raltegravir, processes for their preparation and pharmaceutical compositions comprising them. The present invention also provides crystalline sodium salt of raltegravir, process for its preparation and pharmaceutical compositions comprising it. The present invention further provides a process for the preparation of amorphous sodium salt of raltegravir. The present invention further provides a process for the preparation of raltegravir potassium crystalline form H | 2013-05-30 |
20130137869 | LUMINOPHORES - There is described a non-planar iridium-ligand complex with accessible triplet states and a molecular structure that confers liquid-crystal like properties. | 2013-05-30 |
20130137870 | Tridentate Platinum (II) Complexes - A platinum (II) complex of general formula (II), | 2013-05-30 |
20130137871 | METHOD OF SYNTHESIZING A COMPLEX [MN (NNS)2] ACTIVE AGAINST THE MALARIA PARASITE PLASMODIUM FALCIPARUM - Metal complex of Manganese(II) containing a dithio-based ligand have been synthesized and characterized by elemental analysis, mass spectrometry, Proton NMR and FT-IR spectrometry. A single crystal X-ray structure of the cadmium complex has been analyzed. The metal complex was subjected to biological tests on falcipain-2 (FP-2) and falcipain-3 (FP-3) cysteine protease enzymes from the malaria parasite | 2013-05-30 |
20130137872 | METHOD OF SYNTHESIZING A COMPLEX [CU(NNS)CL] ACTIVE AGAINST THE MALARIA PARASITE PLASMODIUM FALCIPARUM - Metal complex of Copper (II) containing a dithio-based ligand have been synthesized and characterized by elemental analysis, mass spectrometry, Proton NMR and FT-IR spectrometry. A single crystal X-ray structure of the copper complex has been analyzeThis paper describes the synthesis and characterization of the said metal complex containing deprotonated 3-[1-(2-pyridyl) ethylidene]hydrazinecarbodithioate ligand (FIG. | 2013-05-30 |
20130137873 | Polycyclo Dyes and Use Thereof - The invention relates to a family of fluorescent compounds that comprise a bridged polycyclo moiety. The compounds can be chemically linked to biomolecules, such as proteins, nucleic acids, and therapeutic small molecules. The compounds can be used for imaging in a variety of medical, biological and diagnostic applications, and are particularly useful for the in vivo imaging of regions of interest within a mammal. | 2013-05-30 |
20130137874 | One-Pot Preparation of Hexahydroisoquinolines from Amides - The present invention provides an efficient process for the preparation of hexahydroisoquinolines from amides. In particular, the invention provides a good yielding, one-pot process for the synthesis of hexahydroisoquinolines. | 2013-05-30 |
20130137875 | NUCLEIC ACID DETECTIONS AND METHODS OF THEIR USE - The invention describes the preparation and use of fluorescent stains for nucleic acids derived from unsymmetrical cyanine dyes, dimmers, trimers, or tetramers. In particular, the invention describes unsymmetric cyanine dyes, dimmers, trimer and tetramers having a water soluble substituent. The dyes of the invention possess superior fluorescent properties when complexed with nucleic acids, and have utility in any application which requires detection of nucleic acids, such as detection of nucleic acids in solution, in gels, in blots, in microarrays, and in bacteria and cells, and for use in analysis of cell structure, membrane integrity, and function. The presence of the water soluble substituent results in improved water soluability and stability, resulting in improved detection of nucleic acids. | 2013-05-30 |
20130137876 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PEST CONTROL AGENT - The present invention offers compounds or their salts expressed by formula (I) | 2013-05-30 |
20130137877 | ANTIVIRAL COMPOUNDS - The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds. | 2013-05-30 |
20130137878 | PROCESS FOR MANUFACTURE OF TELMISARTAN - A process for preparing telmisartan by reacting 2-n-propyl-4-methyl-6-(1′-methylbenzimidazol-2′-yl)benzimidazole with a compound of formula (IV) | 2013-05-30 |
20130137879 | FLUORESCENT PROBE COMPOUNDS, PREPARATION METHOD AND USE THEREOF - A fluorescence probe compound, its preparation method and use are provided. The said compound is represented by the general formula I, wherein, each of R | 2013-05-30 |
20130137880 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-SUBSTITUTED-3-FORMYL-2-HYDROXYPROPANOIC ACID COMPOUND - The present invention provides a production method of optically active 3-substituted-3-formyl-2-hydroxypropanoic acid compound (4), which includes a step of reacting glyoxylic acid compound (1-1) or (1-2) with aldehyde (2) in the presence of optically active pyrrolidine compound (3); | 2013-05-30 |
20130137881 | METHOD FOR PRODUCING A METHYLENE DISULFONATE COMPOUND - The present invention provides a method for producing a methylene disulfonate compound including reacting, in the presence of an acid and a dehydrating agent, a formaldehyde compound with at least one salt of alkanedisulfonic acid selected from the group consisting of alkali metal salts of alkanedisulfonic acid and alkaline earth metal salts of alkanedisulfonic acid each represented by a specific formula. According to the method of the present invention, a methylene disulfonate compound can be obtained in a simple manner at low cost. | 2013-05-30 |
20130137882 | PROCESS FOR THE SYNTHESIS OF 2,5-FURANDICARBOXYLIC ACID - Process for the synthesis of 2,5-furandicarboxylic acid through the oxidation of -hydroxymethylfurfural in a flow of oxygenor a compound containing oxygen, catalysed by a supported catalyst containing a metal of the platinum group, carried out in aqueous solution in which the pH is maintained higher than 7 and lower than 12 through the addition of a weak base. | 2013-05-30 |
20130137883 | Process for Production of Triterpene Alcohol - A process for producing triterpene alcohol, comprising sequentially conducting the following steps (A) to (C):
| 2013-05-30 |
20130137884 | METHODS FOR THE PURIFICATION OF DEOXYCHOLIC ACID - Synthetic methods for preparing deoxycholic acid and intermediates thereof, high purity synthetic deoxycholic acid, compositions and methods of use are provided. Also, provided are processes for the synthesis of 12-keto or 12-α-hydroxy-steroids from Δ-9,11-ene, 11-keto or 11-hydroxy-β-steroids. This invention is also directed to novel compounds prepared during the synthesis. This invention is also directed to the synthesis of deoxycholic acid starting from hydrocortisone. | 2013-05-30 |
20130137885 | PROCESS FOR INTRODUCING A DOUBLE BOND INTO POSITION 15, 16 OF A STEROID - The invention relates to a process for the preparation of a compound of formula | 2013-05-30 |
20130137886 | Extraction Of Lipids From Living Cells Utilizing Liquid CO2 - A process for the extraction of lipids from living cells utilizing liquid carbon dioxide optionally in the presence of a porous inorganic matrix or polymer coating as well as additional solvents to improve extraction efficiency. The cells may also optionally be treated a photosensitive material to promote cellular photosynthesis. | 2013-05-30 |
20130137887 | PRODUCTION OF TRIACYLGLYCERIDES FROM RENEWABLE BIOMASS USING OLEAGINOUS MICROORGANISMS - The embodiments disclosed herein relate to bacterial cell production of triacylglycerides from renewable biomass resources. | 2013-05-30 |
20130137888 | Catalyst for Akili-Free Purification of Oil Raw Materials from Mercaptans - A catalyst for alkali-free purification of oil raw materials includes a solid metalocomplex or a liquid metalocomplex with a general formula (Cu | 2013-05-30 |
20130137889 | STRECKER REAGENTS, THEIR DERIVATIVES, METHODS FOR FORMING THE SAME AND IMPROVED STRECKER REACTION - Strecker reagents, their derivatives and methods for forming the same and improved Strecker reaction are provided. The electrophiles for asymmetric Strecker reaction include achiral N-phosphorazides, N-phosphoramides, N-phosphonyl imines and their derivatives. The nucleophiles for asymmetric Strecker reaction include chiral BINOL-derived azides, amides, imines and their derivatives, the chiral and achiral diol-based cyanides and their derivatives, the chiral and achiral diamine-based cyanides and their derivatives, the chiral and achiral amino alcohol-based cyanides and their derivatives, the Strecker nucleophiles that are derived from chiral and achiral hydroxyl carboxylic acids and amino acids. Methods of forming the electrophile for asymmetric Strecker reaction comprise the reactions with steps of: a) synthesizing phosphoryl chloride from achiral diamine; b) synthesizing phosphorous azide; c) synthesizing phosphoramide; d) synthesizing the corresponding achiral N-phosphonyl imines. The asymmetric catalytic Strecker reaction of new achiral N-phosphonyl imines has been developed to give excellent enantioselectivity (up to >99% ee) and yields (up to >97%). | 2013-05-30 |
20130137890 | PROCESS FOR THE PREPARATION OF TAPENTADOL - Disclosed herein is an improved process for the preparation of 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol of Formula-I and its pharmaceutically acceptable salt which comprises the reaction of (S)-1-(dimethylamino)-2-methylpentan-3-one of formula VIII with 3-bromo anisole of formula II under Grignard conditions to get the compound (2S, 3R)-1-(dimethylamino)-3-(3-methoxyphenyl)-2-methyl pentan-3-ol of formula V followed by activation of the —OH group of the formula V to convert into sulfonate esters of formula IX, which are on reductive deoxygenation to yield (2R,3R)-3-(3-methoxyphenyl)-N,N,2-trimethylpentan-1-amine of formula VII and demethylation of formula VII to obtain the compound 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol of Formula-1. | 2013-05-30 |
20130137891 | METHOD OF MAKING AMORPHOUS RESIN FOR USE IN ROBUST SOLID INK APPLICATIONS - Methods for making amorphous resins for use in robust solid ink applications are disclosed in which an organic acid is reacted with an alcohol in the presence of a solvent in the amount of from about 0.5 to about 1.5 grams of solvent per gram of reaction product. The reaction product is an ester of tartaric acid or an ester of citric acid. | 2013-05-30 |
20130137892 | PROCESS FOR PREPARING ISOCYANATES BY PHOSGENATION OF THE CORRESPONDING AMINES IN THE GAS PHASE - A process for preparing isocyanates by phosgenation of the corresponding amines in a fluidized-bed reactor (R), wherein a gas stream ( | 2013-05-30 |
20130137893 | PROCESS FOR PREPARING AND PURIFYING SALTS OF ACRYLAMIDO-2-METHYLPROPANESULFONIC ACID - A process for preparing salts of acrylamido-2-methylpropanesulfonic acid (A) using the steps of:
| 2013-05-30 |
20130137894 | CHEMICALLY-MODIFIED GRAPHENE AND METHOD FOR PRODUCING THE SAME - A chemically-modified graphene includes a graphene layer and a plurality of functional groups that are grafted to the graphene layer and each of which is represented by —CO—R—COOH, wherein R is an optionally substituted C | 2013-05-30 |
20130137895 | METHOD FOR THE EXTRACTION OF SHIKIMIC ACID - This invention is directed to the production of shikimic acid from | 2013-05-30 |
20130137896 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND - The present invention provides a novel process for preparing a sulfur-containing 2-ketocarboxylate compound without using any enzyme. The process comprises a step of oxidizing a hydroxyacetate compound having an optionally-substituted sulfur-containing hydrocarbon group at 2-position in the presence of ruthenium metal or a ruthenium compound. Preferably, the step is carried out under pressurized condition, and more preferably, in the presence of at least one typical metal selected from the group consisting of an alkali metal compound and an alkaline earth metal compound. | 2013-05-30 |
20130137897 | PROCESS FOR PREPARING SULFUR-CONTAINING 2-KETOCARBOXYLATE COMPOUND - The present invention provides a novel process for preparing a sulfur-containing 2-ketocarboxylate compound without using any enzyme. The process comprises a step of oxidizing a hydroxyacetate compound having an optionally-substituted sulfur-containing hydrocarbon group at 2-position in the presence of a vanadium compound. Preferably, the step is carried out further in the presence of oxygen, and more preferably, in the presence of an organic solvent. | 2013-05-30 |
20130137898 | Electrochemical Co-Production of Chemicals Utilizing a Halide Salt - The present disclosure includes a system and method for co-producing a first product and a second product. The system may include a first electrochemical cell, at least one second reactor, and an acidification chamber. The method and system for co-producing a first product and a second product may include co-producing a carboxylic acid and at least one of an alkene, alkyne, aldehyde, ketone, or an alcohol while employing a recycled halide salt. | 2013-05-30 |
20130137899 | PROCESS FOR PRODUCING FLUORINE-CONTAINING SULFONYLIMIDE COMPOUND - In this process for producing a fluorine-containing sulfonylimide compound, a process for producing a fluorine-containing sulfonylimide compound ((Rf | 2013-05-30 |
20130137900 | NOVEL METHOD OF PREPARING SECONDARY AMINE COMPOUND USING MICROFLOW REACTOR - Disclosed is a novel method of preparing a secondary amine compound using a microflow reactor. According to the method, a primary amine compound and a halide compound are allowed to react with each other in the microflow reactor, such that the production of a tertiary amine compound or an ammonium salt is minimized, whereby the secondary amine compound is efficiently prepared. | 2013-05-30 |
20130137901 | SYNTHESIS OF POLYALKYLENEPOLYAMINES HAVING A LOW COLOR INDEX BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION IN THE PRESENCE OF HYDROGEN - Process for the preparation of polyalkylenepolyamines by homogeneously catalyzed alcohol amination, in which aliphatic amino alcohols are reacted with one another or aliphatic diamines or polyamines are reacted with aliphatic diols or polyols with the elimination of water in the presence of a homogeneous catalyst and in the presence of hydrogen gas. Polyalkylenepolyamines obtainable by such processes and polyalkylenepolyamines comprising hydroxy groups, secondary amines or tertiary amines. Uses of such polyalkylenepolyamines as adhesion promoters for printing inks, adhesion promoters in composite films, cohesion promoters for adhesives, crosslinkers/curing agents for resins, primers for paints, wet-adhesion promoters for emulsion paints, complexing agents and flocculating agents, penetration assistants in wood preservation, corrosion inhibitors, immobilizing agents for proteins and enzymes. | 2013-05-30 |
20130137902 | Monophosphorus Ligands And Their Use In Cross-Coupling Reactions - Phosphine ligands of the formula Ia, IB and mixtures thereof. | 2013-05-30 |
20130137903 | INTEGRATED PROCESS FOR PRODUCING POLYVINYL ALCOHOL OR A COPOLYMER THEREOF AND ETHANOL - Ethanol is produced from acetic acid or acetic anhydride or a mixture of acetic acid and acetic anhydride by a hydrogenation reaction. The acetic acid or acetic anhydride or a mixture of acetic acid and acetic anhydride is produced from methyl acetate by a carbonylation reaction. The methyl acetate is produced as a byproduct during the conversion of a vinyl acetate polymer or copolymer to a polymer or copolymer of vinyl alcohol. By integrating processes as described herein, a valuable product, i.e. ethanol, is produced from a methyl acetate byproduct. | 2013-05-30 |
20130137904 | INTEGRATED PROCESS FOR PRODUCING POLYVINYL ALCOHOL OR A COPOLYMER THEREOF AND ETHANOL - Ethanol is produced from methyl acetate by a hydrogenolysis reaction. The methyl acetate is produced as a byproduct during the conversion of a vinyl acetate polymer or copolymer to a polymer or copolymer of vinyl alcohol. The hydrogenolysis reaction also produces methanol. At least a portion of this methanol is converted to acetic acid by reaction with carbon monoxide in a carbonylation reaction. At least a portion of this acetic acid is converted to ethanol by a hydrogenation reaction with hydrogen. By integrating the processes as described herein, a valuable product, i.e. ethanol, is produced from a methyl acetate byproduct. | 2013-05-30 |
20130137905 | INTEGRATED PROCESS FOR PRODUCING POLYVINYL ALCOHOL OR A COPOLYMER THEREOF AND ETHANOL - Ethanol is produced from methyl acetate by a hydrogenolysis reaction. The methyl acetate is produced as a byproduct during the conversion of a vinyl acetate polymer or copolymer to a polymer or copolymer of vinyl alcohol. The hydrogenolysis reaction also produces methanol. At least a portion of this methanol is converted to acetic acid by reaction with carbon monoxide in a carbonylation reaction. At least a portion of this acetic acid is converted to vinyl acetate monomer by a reaction with oxygen and ethylene. The vinyl acetate is polymerized to form the vinyl acetate polymer or copolymer. By integrating the two processes, a valuable product, i.e. ethanol, is produced from a methyl acetate byproduct. | 2013-05-30 |
20130137906 | Treatment of Recycle Gas from Acid Hydrogenation - In a process for producing ethanol, acetic acid is contacted with hydrogen in a reaction zone in the presence of a hydrogenation catalyst to form a crude ethanol product comprising ethanol, hydrogen and carbon monoxide. At least a portion of the crude ethanol product is separated to yield a vapor stream and a liquid stream, wherein the vapor stream comprises hydrogen and carbon monoxide, and wherein the liquid stream comprises ethanol. At least a portion of the vapor stream is contacted with a methanation catalyst under conditions such that carbon monoxide reacts with hydrogen in the vapor stream portion to produce a treated stream comprising methane, hydrogen and less carbon monoxide than the vapor stream. At least a portion of the treated stream is returned directly or indirectly to the reaction zone and ethanol is recovered from the liquid stream. | 2013-05-30 |
20130137907 | PROCESS FOR THE PRODUCTION OF MIDDLE DISTILLATE FROM A CONVENTIONAL HEAVY FEEDSTOCK INCLUDING A STEP FOR SELECTIVE HYDROGENATION OF THE EX FCC HCO CUT - The present invention describes a process for the conversion of a heavy feedstock for improving the production and selectivity for middle distillate, said process using a catalytic cracking unit followed by a unit for selective hydrogenation of the heavy distillate cut (HCO) or any other cut rich in triaromatic compounds before recycling it to the FCC reaction zone in order to maximize the middle distillate cut. | 2013-05-30 |
20130137908 | PROCESS FOR DEHYDRATION AND ISOMERIZATION OF C4 ALCOHOLS USING AN AMORPHOUS SOLID WITH SUITABLE POROSITY - The present invention relates to a method of producing C4 olefins, from a feed of C4 monohydric alcohol, in which a reaction of dehydration of the monohydric alcohol to at least one olefin, and a reaction of skeletal isomerization of at least one of the olefins produced in one and the same reaction vessel, are carried out in the presence of an alumina-based catalyst with adapted porosity. | 2013-05-30 |
20130137909 | FLUIDIZED CATALYTIC CRACKING OF PARAFFINIC NAPHTHA IN A DOWNFLOW REACTOR - A process for producing a product stream consisting primarily of the lower olefins ethylene, propylene and butylenes, and of gasoline is provided. The process includes cracking a mixture of paraffinic naphtha feedstream and regenerated catalyst in a downflow reactor. The reaction product stream is separated from the spent catalyst and subsequently fractionated into individual product streams, while the spent catalyst is regenerated and recycled. | 2013-05-30 |
20130137910 | Alkylation Process - The present invention provides an improved process for the catalytic conversion of a feedstock comprising an alkylatable aromatic compound and an alkylating agent to form a conversion product comprising the desired alkylaromatic compound by contacting said feedstock in at least partial liquid phase under catalytic conversion conditions with a catalyst composition comprising a porous crystalline material having a structure type of FAU, BEA* or MWW, or a mixture thereof, wherein the porous crystalline material has a Relative Activity measured at 220° C. as an RA | 2013-05-30 |
20130137911 | CATALYTIC COMPOSITION AND PROCESS FOR THE SELECTIVE DIMERIZATION OF ISOBUTENE - Catalytic composition comprising at least one Brønsted acid, designated HB, dissolved in a non-aqueous liquid medium of general formula Q | 2013-05-30 |
20130137912 | CATALYTIC COMPOSITION CONTAINING AN ACID FUNCTION AND A PROCESS FOR THE SELECTIVE DIMERIZATION OF ISOBUTENE - Catalytic composition comprising at least one non-aqueous ionic liquid medium of general formula Q | 2013-05-30 |
20130137913 | PROCESS FOR THE REJUVENATION OF A SPENT MOLECULAR SIEVE CATALYST - The present invention relates to a process for the rejuvenation of a spent molecular sieve, comprising at least the steps of:
| 2013-05-30 |
20130137914 | PROCESS TO MAKE PROPYLENE FROM ETHYLENE AND EITHER DIMETHYL ETHER, OR METHANOL AND DIMETHYL ETHER - The present invention is a process to make propylene comprising: | 2013-05-30 |
20130137915 | FLEXIBLE ENERGY FILTER FOR ION BEAM THERAPY - An energy filter allows, particularly at lower beam energies, a determined spread of the beam energies in order to preserve the beam edges and to spread the Bragg peak at each individual beam energy. The energy filter behaves similarly to a ridge filter and spreads out the Bragg peak of a low energy proton beam (70-100 MeV) so that energy modulation of the beam can be done with steps of 5 mm in one go over the full range of 235-70 MeV. Due to its mechanical flexibility, the energy filter can be placed on the skin of the patient which minimizes the effect of scattering in the filter due to the short distance behind a layer of a plurality of metal particles within a flexible soft plastic sheet to the skin of the patient. | 2013-05-30 |
20130137916 | RADIOTHERAPY COMBINED WITH HYPOXIC CELL SENSITIZERS - The invention discloses a method of treating cancer in a patient, comprising administering to the patient a radiation sensitizer selected from nitroimidazoles in an amount effective to sensitize a patient to radiation and subjecting the patient to radiation therapy. In certain embodiments the radiation sensitizer is etanidazole or doranidazole. | 2013-05-30 |
20130137917 | Double emulsion core-shell nano-structure and preparation methods thereof - A double-emulsion core-shell nano-structure and preparation methods thereof is provided. The double-emulsion core-shell nano-structure is a structure of an oil shell enclosing a water core. The double-emulsion core-shell nano-structure can be prepared by simply mixing and stirring to emulsify an aqueous solution of a water soluble polymer and an organic solution of hydrophobic paramagnetic nanoparticles. | 2013-05-30 |
20130137918 | DEVICES AND METHODS OF LOW FREQUENCY MAGNETIC STIMULATION THERAPY - Described herein, in certain embodiments, are devices and methods for modulating the electrical activity of a brain in a targeted manner using a weak magnetic field, generally field with a strength of less than about 100 Gauss. The magnetic field is varied over time in a periodic manner, generally with a frequency tuned to specifically affect one of the intrinsic frequencies of the brain, optionally the alpha frequency. The “Low Field Magnetic Stimulation” devices and methods described herein modulate the electrical activity of a brain without requiring medication. Methods and devices described herein gently “tune” the brain and affect mood, focus, and cognition of human subjects. | 2013-05-30 |
20130137919 | MEDITATION ENHANCEMENT BOX HAVING MAGNETS AND BOADING BALL INSIDE - Meditation enhancement box is made of brass or copper, with magnets bonded to each corner and boading ball. The box can be a cube of about 5.08 cm. All magnets are pointed to center of box using a same polarity, and chime sound is produced during usage. Method for using box for meditation as follows: box rests in middle of palm in one hand, feeling weight of box and moving hand slowly clockwise and counterclockwise in circles, and vertical circles, initiating rhythmic breathing while moving hand; upon reaching relaxed state, index finger is placed on top of box and moving from middle towards edge of box in circles; turning over box to one adjacent side in a direction using free hand, followed by breathing in and out for 10 to 15 seconds while rotating the box in one adjacent side, and followed by rotating in another adjacent side, respectively. | 2013-05-30 |
20130137920 | Steerable Guide Member and Catheter - Medical devices are described and illustrated herein. In particular, steerable guide members and catheters useful in the identification and treatment of bodily passages are provided. Methods of identifying and treating bodily passages are also provided. | 2013-05-30 |
20130137921 | PROPELLING SYSTEM AND CAPSULE APPLYING THE SAME - A propelling system disposed in a chamber of a capsule is provided. The propelling system includes a mass and a damping module. The mass is configured for vibrating in the chamber along a plurality of directions. The damping module is coupled between the mass and the capsule for absorbing the kinetic energy of the mass, the damping module provides the smallest damping effect along a first direction. The disclosure further provides a capsule, which includes a shell having a chamber and at least one aforementioned propelling system disposed in the chamber. Accordingly, the capsule can be autonomously propelled by the propelling force autonomously produced by the propelling system. | 2013-05-30 |
20130137922 | Endoscope - An endoscope includes a tube having including a compartment extending in a longitudinal direction. A flexible strip has a diameter smaller than a diameter of the compartment. The flexible strip is received in the compartment and slideable relative to the tube in the longitudinal direction. The flexible strip is made of a super elastomer having an original shape before deformation. The flexible strip is capable of restoring the original shape after larger deformation. An image capturing module is mounted to the flexible strip. The image capturing module can transmit light beam and capture images. | 2013-05-30 |
20130137923 | Endoscope and illumination apparatus for endoscope - An illumination apparatus for an endoscope guiding externally-entering light to a transparent light-guiding body including an annular-shaped annular portion, the annular portion including an inner circumferential face and an outer circumferential face, and making the light exit from the annular portion as illuminating light, wherein the light-guiding body includes: a notch portion formed by cutting out a part of the annular portion so as to form a line extending perpendicularly from the outer circumferential face toward the inner circumference side of the annular portion from a line extending from a point on an outer circumference of a circle in a cross section of the annular portion; and an incident portion that allows the light to enter in a direction along the line extending from the point on the outer circumference, the direction being a direction perpendicular to a cutout surface of the notch portion provided in the annular portion. | 2013-05-30 |
20130137924 | IMAGE PICKUP APPARATUS - An actuator has a magnet moved together with a moving lens frame, an SMA wire capable of extending and contracting in a moving direction I of the moving lens frame with execution or non-execution of energization thereof, a fixing member made of a magnetic material attached to a distal end of the SMA wire, a pressing spring which urges the fixing member toward the magnet along the moving direction I, and a stopper member and a stopper portion which limits the movement of the magnet along the moving direction I at a first position or a second position. | 2013-05-30 |
20130137925 | ENDOSCOPE APPARATUS - A distal end barrel that holds a light guide bundle and an electronic image pickup unit inside a distal end portion is formed in such a manner that the distal end barrel is divided in a first distal end barrel arranged on the distal end side of the distal end portion and a second distal end barrel supported via the first distal end barrel so as not to be exposed at an outer surface of the distal end portion, the second distal end barrel holding the light guide bundle and the electronic image pickup unit, and the second distal end barrel includes a member having a thermal conductivity higher than the thermal conductivity of the first distal end barrel, thereby protecting the image pickup device from thermal damage without an increase in temperature of the outer surface of the distal end portion. | 2013-05-30 |
20130137926 | IMAGE PROCESSING APPARATUS, METHOD, AND PROGRAM - Obtaining a surface image captured by an endoscope inserted in a tubular organ associated with a surrounding blood vessel and representing an inner surface of a wall of the organ, generating, from a three-dimensional image representing a three-dimensional area including the organ, an adjacent blood vessel image depicting a portion of the blood vessel adjacent to the wall from a viewpoint in the three-dimensional image corresponding the viewpoint of the surface image, generating, from a three-dimensional image representing a three-dimensional area including a surrounding area of the organ, a surrounding blood vessel image depicting the blood vessel from a viewpoint in the three-dimensional image corresponding the viewpoint of the surface image, and causing the surface image, adjacent blood vessel image, and surrounding blood vessel image to be displayed in this order on a display unit. | 2013-05-30 |