22nd week of 2009 patent applcation highlights part 47 |
Patent application number | Title | Published |
20090137802 | A2B ADENOSINE RECEPTOR ANTAGONISTS - Disclosed are processes for the synthesis of novel compounds that are A | 2009-05-28 |
20090137803 | 5-PROTECTED AMINOPYRIMIDINE COMPOUND, PRODUCTION METHOD THEREOF AND INTERMEDIATE THEREFOR - The present invention provides a production method of 5-aminopyrimidine compound represented by the formula (5) by reacting a glycine compound represented by the formula (1) with t-butoxybisdimethylaminomethane, dimethylformamidedimethylacetal or dimethylformamidediethylacetal to produce a dialkylaminomethylene compound represented by the formula (2), reacting the compound of formula (2) in the presence of an acid to produce a hydroxymethylene compound represented by the formula (3), and reacting the compound of formula (3) with an amidine compound represented by the formula (4) or a salt thereof. | 2009-05-28 |
20090137804 | Compounds and Compositions as Protein Kinase Inhibitors - The invention relates to compounds of formula (I) | 2009-05-28 |
20090137805 | N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES - The present invention relates to novel amides and a process for preparing these amides. | 2009-05-28 |
20090137806 | DUAL NK1/NK3 RECEPTOR ANTAGONISTS - The present invention provides a method for the treatment of schizophrenia which comprises administering a compound of formula | 2009-05-28 |
20090137807 | Electrochromic material with improved lifetime - Disclosed are viologen derivatives as an electrochromic material having improved stability and lifetime, a metal oxide electrode including the same, and an electrochromic device using the viologen derivative as an electrochromic material. The viologen derivative includes a suitable regulator group capable of increasing ΔE that is a potential difference between E | 2009-05-28 |
20090137808 | PROCESS FOR MANUFACTURING BISPHOSPHONIC ACIDS - A manufacturing process for the preparation of bisphosphonic acids and in particular zoledronic acid is provided wherein diglyme, monoglyme, or a mixture thereof, is utilized to produce a homogenous, water soluble, solid reaction mass that upon cooling, dissolving in water and stripping results in a high purity product and comparatively good yield. wherein Ri is selected from the group consisting of | 2009-05-28 |
20090137809 | Demethylation of 14 hydroxy substituted alkaloid derivatives - The present invention is directed to a method for demethylating 14-hydroxy substituted alkaloid derivatives, in particular of 14-hydroxy-17-methyl-4,5-epoxymorphinane-6-on-derivatives. This is achieved by reacting a starting compound with a compound of general formula R | 2009-05-28 |
20090137810 | Synthetic Methods and Intermediates for Stereoisomeric Compounds Useful for the Treatment of Gastrointestinal and Central Nervous System Disorders - The subject invention provides methods and/or processes for making stereoisomeric compounds of formula (X): | 2009-05-28 |
20090137811 | PROCESS FOR THE PREPARATION OF DONEPEZIL AND INTERMEDIATE COMPOUNDS THEREOF AS WELL AS HYDRATES OF DONEPEZIL - The present invention relates to a new process for the preparation of intermediate compounds useful in the manufacture of donepezil, or a pharmaceutically-acceptable salt thereof, and also relates to processes for preparing donepezil and to the novel intermediates per se. In addition the invention relates to various hydrated forms of donepezil. | 2009-05-28 |
20090137812 | PROCESS FOR PRODUCING 1-BENZYL-4-[5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE - Disclosed herein the process for producing 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2yl)methyl]piperidine or its salt thereof employing novel intermediates. | 2009-05-28 |
20090137813 | PROCESS FOR PRODUCTION OF CAREBASTINE - Processes are disclosed for preparing piperidine derivative compounds of the formulae I, II or III: | 2009-05-28 |
20090137814 | Synthesis of diaminodinitropyridine - A process for the preparation of diaminodinitropyridine or diaminodinitrobenzene by contacting an aminopyridine or aminobenzene with oleum and nitric acid, wherein the improvement comprises adding at least about 1% molar excess of nitric acid, based upon the aminopyridine or aminobenzene, with stirring for at least two hours to form first the intermediate sulfonic acid, and then diaminodinitropyridine or diaminodinitrobenzene, and use of such products in the preparation of rigid rod polymers is disclosed. | 2009-05-28 |
20090137815 | Process for Making Cytokine Inhibiting Compounds Containing 4- and 5-Imidazolyl Rings and the Intermediates Thereof - Disclosed are processes for making compounds containing 4- and 5-imidazolyl rings, also disclosed are the inter-mediates useful in the processes disclosed herein. | 2009-05-28 |
20090137816 | Process for the manufacture of diaminofurazan - This invention consists of a method for converting diaminoglyoxime to diaminofurazan that can be carried out efficiently at about atmospheric pressure without the need for high pressure containment apparatus. | 2009-05-28 |
20090137817 | SPATIALLY-DEFINED MACROCYCLIC COMPOUNDS USEFUL FOR DRUG DISCOVERY - Novel spatially-defined macrocyclic compounds containing specific conformational control elements are disclosed. Libraries of these macrocycles are then used to select one or more macrocycle species that exhibit a specific interaction with a particular biological target. In particular, compounds according to the invention are disclosed as agonists or antagonists of a mammalian motilin receptor and a mammalian ghrelin receptor. | 2009-05-28 |
20090137818 | Crystal structure of human coronavirus 229E main proteinase and uses for developing SARS inhibitors - The invention relates to a method of developing a main proteinase SARS inhibitor. Human coronaviruses are major causes of upper respiratory tract illnesses in humans, in particular, the common cold. Recent investigations have shown that a novel coronavirus causes the Severe Acute Respiratory Syndrome (SARS), a disease that is characterized by high fever, malaise, rigor, headache, non-productive cough or dyspnea, which is rapidly spreading. Within the scope of the invention, based on the structural analysis of the binding mode of the SARS M | 2009-05-28 |
20090137819 | Method of Producing Optically Active 4-Amino-3-Substituted Phenylbutanoic Acid - The present invention provides a method of producing a compound (IIa) or a compound (IIb), provides a method of producing a compound (IIIa) or a compound (IIIb), provides a method of producing a compound (Va) or its salt or a compound (Vb) or its salt, provides a method of producing a compound (IIIa) or a compound (IIIb), further, provides a method of producing a compound (Va) or its salt or a compound (Vb) or its salt including these production methods. | 2009-05-28 |
20090137820 | PROCESS FOR PRODUCTION OF METHYLENE DISULFONATE COMPOUND - The present invention provides a process for producing a methylene disulfonate compound in a simple manner at low cost. | 2009-05-28 |
20090137821 | Method of making dorzolamide hydrochloride - Processes for the preparation of dorzolamide hydrochloride and an intermediate of Formula IV, | 2009-05-28 |
20090137822 | Process for preparing 3-substituted thiophene - The present invention relates to a process for preparing a 3-substituted thiophene represented by the formula (2): | 2009-05-28 |
20090137823 | (E)-N-Monoalkyl-3-Oxo-3-(2-Thienyl) Propenamine and Process for Producing the Same and Process for Producing (E,Z)-N-Monoalkyl-3-Oxo-3-(2-Thienyl) Propenamine - The present invention provides a process for producing (E)-N-monoalkyl-3-oxo-3-(2-thienyl)propenamine represented by Formula (1); | 2009-05-28 |
20090137824 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES - The present invention concerns a metallocene-based phosphine ligand for use in enantioselective catalysis, the ligand having the Formula (I): Wherein M is a metal; Z is P or As; L is a suitable linker; R | 2009-05-28 |
20090137825 | METHOD OF PRODUCING A CARBOXYLIC ALKYL ESTER - The present invention relates to a novel process for preparing alkyl polycarboxylates from an aqueous solution of an ammonium salt of the polycarboxylic acid by reactive distillation, and to a process for hydrogenating the alkyl carboxylates prepared in this way. | 2009-05-28 |
20090137826 | Method for preparing 4beta-amino-4'-demethyl-4-desoxypodophyllotoxin - The invention relates to a method for synthesizing 4β-amino-4′-demethyl-4-desoxypodophyllotoxin of formula (1), characterized by comprising the following successive steps: a) reacting, in a pure weak acid or in a mixture consisting of acid, water and of organic solvent, without another solvent, at a temperature higher than the ambient temperature, thiourea with 4β-halogenoacetamido-4′-demethyl-4-desoxypodophyllotoxin, and; b) recovering the 4β-amino-4′-demethyl-4-desoxypodophyllotoxin. | 2009-05-28 |
20090137827 | SILICON-TITANIUM MIXED OXIDE-CONTAINING DISPERSION FOR THE PRODUCTION OF TITANIUM-CONTAINING ZEOLITES - Dispersion containing pyrogenic silicon-titanium mixed oxide powders with a silicon dioxide content of 75 to 99.99 wt.-% and a titanium dioxide content of 0.01 to 25 wt. %, water and a basic, quaternary ammonium compound, wherein the mean aggregate diameter of the particles of the silicon-titanium mixed oxide powder in the dispersion is 200 nm at most. Process for the production of a titanium-containing zeolite with the use of the dispersion. | 2009-05-28 |
20090137828 | Synthesis of 1A-Fluoro-25-Hydroxy-16-23E-Diene-26,27-Bishomo-20-Epi-Cholecalciferol - The invention provides a method of producing 20-methyl vitamin D3 compounds of formula (I). The method includes allylic and olefin oxidation, de-carbonylation, carbonyl reduction, fluoride substitution, epoxide deoxygenation, and Wittig-type couplings. | 2009-05-28 |
20090137829 | Methods for Preparation and Use of Strong Base Catalysts - Methods for preparation of a unique superbase catalyst consisting of mixture of polyether alcohol and base in which a polyether alcohol superbase is produced by the removal of water or alcohol at elevated temperatures to form a polyether alcohol alkoxide. The superbase catalyst is useful in, but not limited to, quantitative isomerization of alkyl esters of vegetable oils containing interrupted double bond systems to yield esters with conjugated double bond systems, alkylations, arylations, acylations, aminations, condensations, eliminations, isomerizations, rearrangements, and Wittig reactions. | 2009-05-28 |
20090137830 | Process for the preparation of a metal-organic compound comprising a spectator ligand - The invention relates to a process for the production of an organometallic compound according to formula (1): MAL | 2009-05-28 |
20090137831 | Fluorinated Alkanesulfonic Acid Esters and Amides and Processes for Making and Using the Same - The invention provides novel aryl and aliphatic esters of fluorinated alkanesulfonic acids. The invention also provides novel fluorinated alkanesulfonamides and a process to make the same. The invention also provides a process for the arylation of an amine by contacting the amine with an aryl ester of a fluorinated alkanesulfonic acid. | 2009-05-28 |
20090137832 | PROCESSES FOR PURIFYING DIARYL CARBONATES - Processes comprising: transesterifying a dialkyl carbonate and an aromatic hydroxyl compound in the presence of a transesterification catalyst to provide a diaryl carbonate product comprising the transesterification catalyst as an impurity; subjecting the diaryl carbonate product to distillation in a first distillation column having an upper part and a lower part, wherein the upper part comprises a rectifying section and the lower part comprises a stripping section; and withdrawing a first sidestream from the first distillation column, wherein the first sidestream comprises a purified diaryl carbonate. | 2009-05-28 |
20090137833 | Process for industrially producing dialkyl carbonate and diol - It is an object of the present invention to provide a specific process that enables a dialkyl carbonate and a diol to be produced on an industrial scale of not less than 2 ton/hr and not less than 1.3 ton/hr respectively with high selectivity and high productivity stably for a prolonged period of time through a reactive distillation system of taking a cyclic carbonate and an aliphatic monohydric alcohol as starting materials, continuously feeding the starting materials into a continuous multi-stage distillation column in which a catalyst is present, and carrying out reaction and distillation simultaneously in the column. Although there have been many proposals regarding processes for the production of the dialkyl carbonate and the diol through the reactive distillation method, these have all been on a small scale and short operating time laboratory level, and there have been no disclosures whatsoever on a specific process or apparatus enabling mass production on an industrial scale. According to the present invention, there is provided a specific continuous multi-stage distillation column having a specified structure, and a production process using this continuous multi-stage distillation column, according to which the dialkyl carbonate and the diol can be produced on an industrial scale of not less than 2 ton/hr and not less than 1.3 ton/hr respectively each with a selectivity of not less than 95%, preferably not less than 97%, more preferably not less than 99%, stably for not less than 1000 hours, preferably not less than 3000 hours, more preferably not less than 5000 hours. | 2009-05-28 |
20090137834 | LEVODOPA PRODRUGS, AND COMPOSITIONS AND USES THEREOF - Prodrugs of levodopa, methods of making prodrugs of levodopa, methods of using prodrugs of levodopa, and compositions of prodrugs of levodopa are disclosed. | 2009-05-28 |
20090137835 | PROCESSES FOR INTERMEDIATES FOR MACROCYCLIC COMPOUNDS - The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates: | 2009-05-28 |
20090137836 | PROCESSES FOR PREPARING LOW-ACID POLYALKYLENE TEREPHTHALATE FROM DIOL-CAPPED PRE-POLYMER AND LINEAR OLIGOMER RECYCLATE AND USING SUCH IN THE PRODUCTION OF MACROCYCLIC POLYESTER OLIGOMER - The invention relates to a method for producing low-acid polyalkylene terephthalate from which MPO can be advantageously manufactured. In certain embodiments, low-acid polybutylene terephthalate (PBT) is prepared by reacting low molecular weight, diol-stopped PBT pre-polymer with a linear oligomer recyclate in refluxing ortho-dichlorobenzene (oDCB) solvent. The linear oligomer recyclate may be a by-product of the depolymerization/cyclization of the low-acid PBT, thereby synergistically increasing overall conversion of reactants to the MPO product, cyclic polybutylene terephthalate (cPBT). | 2009-05-28 |
20090137837 | METHODS OF SYNTHESIZING CINACALCET AND SALTS THEREOF - Methods of preparing cinacalcet, cinacalcet derivatives, and salts thereof is disclosed herein. Also disclosed herein are polymorphs of cinacalcet, compositions of cinacalcet, and methods of treating a subject by administering cinacalcet, wherein cinacalcet is prepared by the disclosed methods. | 2009-05-28 |
20090137838 | Esters with antimicrobial, bioresistant and fungal resistant properties - A bromine/nitro moiety linked into the backbone of an ester or other compound over a wide range of occurrence rates provides antimicrobial, bio-resistant and fungal resistant properties for metal working fluids (MWF)s and other coatings. The moiety can be have the bromo and nitro groups linked to the same or different carbon atoms. The present invention also relates to urethanes, urea, amides, imides, carbonates, ethers, siloxanes, and many other types of linkages essential to MWF bases. | 2009-05-28 |
20090137839 | METHOD FOR PRODUCING (2-FORMYL-1-ALKENYL) CYCLOPROPANE COMPOUND - A method for producing a (2-formyl-1-alkenyl)cyclopropane compound represented by the formula (1): | 2009-05-28 |
20090137840 | Fluorinated Alkanesulfonic Acid Anhydrides and Processes for Making the Same - The invention provides a process for the preparation of fluorinated alkanesulfonic acid anhydrides by contacting alkanesulfonic acids with phosphorus pentoxide, the phosphorus pentoxide being provided as a dispersion in an inert oil. The invention also provides novel fluorinated alkanesulfonic acid anhydrides including 2-hydrotetrafluoroethanesulfonic acid anhydride. | 2009-05-28 |
20090137841 | PROCESS FOR THE PREPARATION OF AROMATIC DERIVATIVES OF 1-ADAMANTANE - Process for the obtaining of 1-adamantane (tricycle[3.3.1.1 (3,7)]decane) derivatives, or of a pharmaceutically acceptable salt thereof, based on a carboxylation reaction, via metallation, of a precursor compound with an adequate leaving group. It also comprises the preparation of the precursor compound by means of a selective coupling of the corresponding boron, magnesium or zinc derivative with the corresponding disubstitute aromatic derivative. It is especially useful for the obtaining of Adapalene at industrial scale with good yield and high purity. | 2009-05-28 |
20090137842 | PREGABALIN -4-ELIMINATE, PREGABALIN 5-ELIMINATE, THEIR USE AS REFERENCE MARKER AND STANDARD, AND METHOD TO PRODUCE PREGABALIN CONTAINING LOW LEVELS THEREOF - The present invention provides 3-(aminomethyl)-5-methylhex-4-enoic acid (Pregabalin-4-eliminate or PRG-4E) and 3-(aminomethyl)-5-methylhex-5-enoic acid (Pregabalin-5-eliminate or PRG-5E), and their uses as reference markers and standards for determining the purity of Pregabalin. The invention also provides a method to produce Pregabalin containing low levels of these impurities. | 2009-05-28 |
20090137843 | METHOD FOR PRODUCING ORGANIC ACID - A novel method is provided whereby a free organic acid can be produced particularly from an ammonium salt of an organic acid having a high melting point obtainable by bioconversion of a carbon source in the presence of a neutralizing agent, efficiently at a low cost, and the used material for reaction and a byproduct can be recycled for reuse without being disposed. | 2009-05-28 |
20090137844 | Crystallization process - The invention relates to a process for the production of tamsulosin hydrochloride crystals where the crystal size distribution is controlled by controlling the temperature where hydrochloric acid is added to the reaction mixture. | 2009-05-28 |
20090137845 | Novel 4-Dedimethylaminotetracycline derivatives - The present invention provides new chemically modified 4-dedimethylaminotetracycline compounds that can be substituted with aryl, alkenyl, or alkynyl groups. The 7, 8, and/or 9 positions and methods for preparing such compounds. Other tetracycline compounds include the 4-dedimethylaminotetracycline derivatives with an oxime group, NH-Alkyl, or N—NH-Alkyl group substituted at the C4 position as well as C2 Mannich derivatives. The present invention also provides a method of treating a mammal suffering from conditions or diseases by administering to the mammal an effective amount of the new chemically modified tetracycline compounds. | 2009-05-28 |
20090137846 | Processes for the synthesis of O-Desmethylvenlafaxine - The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine. | 2009-05-28 |
20090137847 | Decomposing system for polyisocyanate residues, and start-up method for the same - An object of the invention is to provide a decomposing system for polyisocyanate residues that is capable of suppressing reaction of polyisocyanate residues with high temperature and high pressure water to allow smooth start-up of the operation, and a start-up method for the decomposing system for the polyisocyanate residues. The decomposing system is used for hydrolyzing the polyisocyanate residues to polyamine using high temperature and high pressure water, comprising a hydrolyzer, a water feed pipe connected to the hydrolyzer, a residual feed pipe connected to the water feed pipe, a solvent feed line for filling an organic solvent in a solvent filling portion of the residual feed pipe, and a solvent draining line. Upon start-up of the operation, the organic solvent is previously filled in the solvent filling portion via the solvent feed line and the solvent draining line, first, and then, the high temperature and high pressure water is fed from the water feed pipe to the hydrolyzer. Then, the organic solvent is fed from the residual feed pipe to the water feed pipe, first, and then, the polyisocyanate residues are fed thereto. | 2009-05-28 |
20090137848 | PROCESS FOR THE MANUFACTURE OF POLYPHENOLS - An improved process for the manufacture of a polyphenol compound such as bisphenol-A by introducing into a reaction zone a phenolic compound reactant, a carbonyl compound reactant, and a catalyst promoter comprising bismethylthiopropane added to the reaction system in certain specific locations, and reacting the ingredients within the reaction zone in the presence of an acid catalyst. | 2009-05-28 |
20090137849 | METHOD FOR THE SEPARATION OF POLYMERIC BY-PRODUCTS FROM 1,4-BUTYNEDIOL - The present invention relates to processes for making 1,4-butanediol, 1,4-butenediol, or a mixture thereof by processing 1,4-butynediol in a dynamic mixing apparatus in an inert gas atmosphere at from 25 to 150° C. at a shear rate in the radial gap between rotor and stator of the mixing apparatus of more than 100 000 sec | 2009-05-28 |
20090137850 | Method for Hydrating Olefins - A novel olefin hydration method is provided for efficiently producing alcohols by hydration of olefins containing 2 to 5 carbon atoms in the presence of a catalyst. Thus, alcohols are produced by hydrating olefins containing 2 to 5 carbon atoms at reaction temperature of 100 to 250° C. in the presence of a solid acid catalyst consisting of carbonaceous materials containing sulfonic acid groups obtained from an organic matter by carbonization and sulfonation. In carrying out this method, the organic matter is preferably an aromatic hydrocarbon or a saccharide, the olefin is preferably propylene or a butenes, and the hydration reaction temperature is not lower than 120° C., more preferably not lower than 150° C. | 2009-05-28 |
20090137851 | Purification of glycerin obtained as a bioproduct from the transesterification of triglycerides in the synthesis of biofuel - Methods for purifying glycerin contaminated with one or more lower boiling alcohols such as methanol, ethanol, straight, branched or cyclic C3-C6 alcohols, and the like. The methods are particularly useful for purifying crude glycerin phases recovered from the synthesis of biofuels. The present invention uses distillation techniques to strip alcohol contaminants from glycerin. In contrast to conventional methods that carry out distillation either under substantially anhydrous or very wet conditions, the present invention carries out distillation in the presence of a limited amount of water, e.g., from about 0.8 to about 5 parts by weight of water per 100 parts by weight of contaminated glycerin to be purified. | 2009-05-28 |
20090137852 | METHOD FOR PRETREATING AND REGENERATING CATALYSTS USED IN A PROCESS FOR MAKING FLUOROIODOALKANES - A process for the preparation of a fluoroiodoalkane represented by the structural formula CF | 2009-05-28 |
20090137853 | Process for the Preparation of 1,1,1,3,3-Penta-Fluoropropane and/or 1,1,1,3,3,3-Hexafluoropropane - A process for the manufacture of CF | 2009-05-28 |
20090137854 | Integration of molecular redistribution and hydroisomerization processes for the production of paraffinic base oil - The process as described herein produces a moderately aromatic isoparaffinic base oil from a distillate range product. This process comprises: (a) providing a distillate range paraffin feed comprising paraffins and cycloparaffins; (b) mildly reforming the distillate range paraffin feed to convert at least a portion of the cycloparaffins to alkylaromatics and provide a mildly reformed distillate range stream; (c) treating a stream comprising the mildly reformed distillate range stream in a molecular redistribution reactor to provide a distributed stream; (d) dewaxing at least a portion of the distributed stream to provide a dewaxed stream; (e) combining at least a portion of the dewaxed stream with the stream to be processed in the molecular redistribution reactor to provide the distributed stream; and (f) isolating a moderately aromatic isoparaffinic base oil from the dewaxed stream. According to another aspect, the process generates low ring content isoparaffinic base oil by hydrotreating the moderately aromatic isoparaffinic base oil. | 2009-05-28 |
20090137855 | Alkylaromatics Production - A process is described for producing an alkylaromatic compound in a multistage reaction system comprising at least first and second series-connected alkylation reaction zones each containing an alkylation catalyst. A first feed comprising an alkylatable aromatic compound and a second feed comprising an alkene and one or more alkanes are introduced into said first alkylation reaction zone. The operating conditions, e.g. temperature and pressure, of the first alkylation reaction zone are controlled effective to cause the alkylatable aromatic compound to be partly in the vapor phase and partly in the liquid phase, and the ratio of the volume of liquid to the volume of vapor of the feed in each zone to be from about 0.1 to about 10. The aromatic compound and the alkene of the feed are reacted in the presence of the alkylation catalyst to form an effluent comprising the alkylaromatic compound, unreacted alkylatable aromatic compound, any unreacted alkene and the alkane. The effluent is withdrawn from the first alkylation reaction zone and then supplied to the second alkylation reaction zone without removal of the alkane. | 2009-05-28 |
20090137856 | METHOD AND DEVICE FOR PRODUCING LOWER OLEFINS FROM OXYGENATES - Method and device for manufacturing at least one low olefin from an oxygenate-containing first reaction mixture ( | 2009-05-28 |
20090137857 | METHOD FOR PREPARATION OF ETHYLENE AND PROPYLENE BY CATALYTIC CRACKING USING A FLUID-BED CATALYST - A method for preparation of ethylene and propylene by catalytic cracking using a fluid-bed catalyst. The main technical problems to be solved are a relatively high reaction temperature, and low activities and poor selectivities of the catalyst at a low temperature, during the reaction for preparing ethylene and propylene by catalytically cracking naphtha. The fluid-bed catalyst is a composition of the chemical formula Mo | 2009-05-28 |
20090137858 | SYSTEM AND METHOD FOR TREATING INFECTIOUS WASTE MATTER - A system and method is provided for producing a safely disposable end product from waste matter containing undesirable materials, such as infectious, biohazardous, hazardous, or radioactive elements. The method comprises the steps of providing a highly alkaline solvent, immersing the waste matter containing the undesirable materials within the highly alkaline solvent, and heating the solvent. The waste matter containing the undesirable materials is allowed to remain within the solvent until digested, thereby forming a solution void of any infectious or biohazardous elements and/or containing a decreased concentration of radioisotope. | 2009-05-28 |
20090137859 | PASSAGE EXPANSION DEVICE FOR PATIENTS - A method for opening a portion of a passageway of a patient is disclosed. The patient has a first metallic structure attached to a portion of the patient's neck. The method includes obtaining a second magnetic structure, placing the second magnetic structure proximate the first metallic structure attached to the portion of the patient's neck, and pulling the second magnetic structure away from the patient's neck to thereby open the passageway. | 2009-05-28 |
20090137860 | Biomedical Device for Treating by Virtual Immersion - The invention relates to a biomedical device comprising computing means, immersion means for dipping a patient in a virtual intelligent environment, an interface for controlling the computing means, operating the immersion means and for collecting results of related medical means and different means for obtaining said results. The inventive device is characterized in that the computing means are used for controlling the immersion means in such a way that virtual three-dimensional therapeutic environments comprising a virtual person in the form of the patient, a closed three-dimensional envelop emitting at a determined light frequency which envelops the person and any scenery in which the virtual person and the closed radiating envelop thereof are located for receiving a determined psycho-neuro-immunologic response, which is positive for the organism, are formed. In particular the inventive method consists in progressively increasing the light frequency of the closed envelop and of the person receiving said radiation. | 2009-05-28 |
20090137862 | ADJUSTABLE TISSUE SUPPORT MEMBER - The present disclosure relates to implants having two arms and a support portion configured to support a body tissue, such as a urethra. The implants are anchored in soft tissue with tissue anchors having a plurality of barbs. The tissue anchors contain an aperture through which a portion of arm is maintained. A locking member is disposed within at least one of the arms to facilitate fixation of the arm to at least one of the anchors. | 2009-05-28 |
20090137863 | Heart wall tension reduction apparatus - An apparatus for treatment of a failing heart by reducing the wall tension therein. In one embodiment, the apparatus includes a tension member for drawing at least two walls of a heart chamber toward each other. | 2009-05-28 |
20090137864 | Method and apparatus for treating pelvic organ prolapse - A method of treating pelvic organ prolapse is provided. The method generally includes the steps of establishing a first pathway between the external perirectal region of the patient to the region of the ischial spine in tissue on one side of the prolapsed organ, followed by establishing a second pathway in tissue on the contralateral side of the prolapsed organ. A support member, which includes a central support portion and two end portions, is positioned in a position to reposition said prolapsed organ in said organ's anatomically correct location. The end portions of the support member are introduced through the respective tissue pathways, followed by adjustment of the end portions so that the support member is located in a therapeutic relationship to the prolapsed organ that is to be supported. An apparatus and kit for said treatment is further provided. | 2009-05-28 |
20090137865 | Tissue Stabilizer and Methods of Use - Devices and methods are disclosed for stabilizing tissue within a patient's body during a surgical operation to provide a relatively motionless surgical field. The devices involve tissue stabilizers which provide superior engagement with a tissue structure to be stabilized, for example the beating heart. The tissue stabilizer may have one or more stabilizer feet which provide for adjustment of the orientation of the features which engage the surface of the tissue structure. In one instance, the orientation may be adjusted to ensure the engaging features will be properly aligned with the surface of the tissue structure before engagement. In addition, once engaged with or connected to the tissue structure the orientation may be adjusted to yield an optimum surgical presentation of a portion of the tissue structure, for instance a coronary artery or the like. The tissue stabilizer may be configured to use friction, negative pressure, or both to engage the surface of the heart. | 2009-05-28 |
20090137866 | Medical or veterinary digestive tract utilization systems and methods - Systems and methods are described for implementing or deploying medical or veterinary utility modules (a) operable for mooring at least partly within a digestive tract, (b) small enough to pass through the tract per vias naturales and including a wireless-control component, (c) having one or more attachment protrusions positionable adjacent to a mucous membrane, (d) configured to facilitate redundant modes of attachment, (e) facilitating a “primary” material supply deployable within a stomach for an extended and/or controllable period, (f) moored by one or more adaptable extender modules supported by a subject's head or neck, and/or (g) configured to facilitate supporting at least a sensor within a subject's body lumen for up to a day or more. | 2009-05-28 |
20090137867 | ENDOSCOPE TREATMENT SYSTEM - An endoscope treatment system includes: an endoscope; and a treatment tool that has a sheath that is inserted in a channel of an insertion portion of the endoscope, in which projection portions that project outward from the sheath in the radial direction are provided, and engagement portions that engage the projection portions are provided near the channel of the endoscope. | 2009-05-28 |
20090137868 | ENDOSCOPE SYSTEM - An endoscope system of the invention includes: a first endoscope capable of picking up an image of a subject; a first illuminating section capable of emitting first illuminating light; a second endoscope capable of picking up an image of the subject illuminated by the first light from a direction different from the first endoscope; a second illuminating section capable of emitting second illuminating light; a video signal processing section for generating a video signal based on a signal picked-up by the second endoscope; a display section for displaying an image of the subject obtained by the video signal processing section; an emphasis instructing section for instructing an emphasis on an image obtained based on the first light; and an emphasis control section for controlling to emphasize the subject image obtained based on the first light according to an operation of the emphasis instructing section. | 2009-05-28 |
20090137869 | SELF-ADVANCING DEVICE - A device which includes an elongate body with a movable mass arranged for sliding movement within the body is disclosed. The element is arranged to decelerate toward an end of the body in order to impart forward movement thereto, via momentum transfer, and is further arranged to accelerate away from said end in order to further drive the body forward, again using momentum transfer. | 2009-05-28 |
20090137870 | Transparent Dilator Device and Method of Use (END-900) - A medical device for use with an endoscope is provided. The medical device can include a tube with a first channel for receiving the endoscope. A transparent segment can extend from the distal end of the tube, and the transparent segment can have a first outer diameter sized for providing dilation of a portion of a body lumen. The medical device can also include a tapered tip attached to the distal end of the transparent segment that narrows from the first outer diameter to a distal terminating end. The endoscope is used to view the body lumen through the medical device while in use to dilate a stricture under direct visualization. | 2009-05-28 |
20090137871 | RADIO OBSERVATION DEVICE - A radio observation device which transmits information on observation subjects has a first coil, an oscillator, a first frequency controller, a frequency-measuring device, and a transmitter. The oscillator generates signals flowing through the first coil within a certain range of frequencies. The first frequency controller is connected to the oscillator, and adjusts the oscillating frequency of the signal flowing through the first coil by controlling said oscillator. The frequency-measuring device measures a resonance frequency of a signal flowing through the first coil and a signal flowing through a second coil being provided external to the radio observation device. The transmitter transmits the information on the observation subjects through said first coil by a carrier wave which oscillates at the resonance frequency. | 2009-05-28 |
20090137872 | Method and Apparatus for Controlling Endoscopic Instruments - An apparatus for the control of endoscopic instruments includes a control module mountable to a standard instrument port of an endoscope. The control module includes separate drive mechanisms for a sheath and a tensile cord of an endoscopic tool having an end effector. Driving the sheath and the tensile cord together may serve to advance or withdraw the end effector, driving either component separately may cause all activation of the end effector. | 2009-05-28 |
20090137873 | IN-VIVO INFORMATION ACQUIRING SYSTEM AND BODY-INSERTABLE APPARATUS - An in-vivo information acquiring system includes a body-insertable apparatus that transmits a wireless signal containing an in-vivo image, and a receiving apparatus that receives the wireless signal. The body-insertable apparatus includes an imaging unit, a selecting unit, and a transmitting unit. The imaging unit captures in-vivo images. The selecting unit selects an in-vivo image to be added with unique information from the in-vivo images. The transmitting unit additionally arranges an identification signal, which is written according to a signal sequence rule of synchronization signals added to scanning line information about the in-vivo image selected by the selecting unit, in a position corresponding to positions in which the synchronization signals are arranged, adds unique information corresponding to the identification information after the identification information, and transmits the in-vivo image added with the unique information. | 2009-05-28 |
20090137874 | Polymer Microvalve with actuators and devices - The present invention relates to a microvalve having a valve plug, connecting legs, anchors and actuators, allowing the valve plug to move vertically to open or close the valve. The valve plug can contain magnetic materials, and be operated by an actuator. | 2009-05-28 |
20090137875 | ENDOSCOPE INSERTION PORTION - An easy-to-manufacture endoscope is provided. | 2009-05-28 |
20090137876 | DIAGNOSTIC CAPSULE WITH PERIPHERAL IMAGING - A diagnostic capsule is disclosed having at least one light source; a rotatable substrate having at least one optical bench; at least one photo-sensitive region; and a circumferential window having an axis substantially parallel to an axis of rotation of the rotatable substrate. Related systems for use with a diagnostic capsule are also disclosed. An endoscopic diagnostic map is further disclosed. The endoscopic diagnostic map has a first dimension corresponding to a rotational position of at least one optical bench on a rotatable substrate of a diagnostic capsule. The endoscopic diagnostic map also has a second dimension corresponding a traveled position of the diagnostic capsule. Related methods of generating an endoscopic | 2009-05-28 |
20090137877 | TISSUE RETRACTORS - Methods and devices are provided for performing surgical procedures using tissue retractors. In general, a surgical retractor device is provided that includes a flexible fabric tissue retractor configured to support tissue. At least one grasping element can be coupled to a perimeter of the flexible fabric, and the grasping elements can be manipulated to couple the flexible fabric to a surgical port, e.g., a trocar, inserted through a body wall and extending into a body cavity. The grasping element can also be configured to move the flexible fabric and thereby move the tissue. | 2009-05-28 |
20090137878 | Flexible, Selectively Rotatable Tissue Retractor and Method for Using the Retractor - A retractor for manipulating an object, the retractor includes a retractor body with proximal and distal ends, a retraction device with a head connected at the distal end of the retractor body and flexible needles of a shape memory material having a memory shape, the memory shape of the needles including a portion with an arcuate shape housed, at least partially, within the head. The retractor further includes an actuation device connected to the proximal end of the retractor body and operatively connected to the needles, the actuation device, upon actuation thereof, moving the needles out of the head and withdrawing the needles into the head and a rotation joint allowing the distal end of the retractor body and the retraction device to rotate independent of the proximal end of the retractor body. | 2009-05-28 |
20090137879 | SURGICAL ACCESS APPARATUS AND METHOD - A surgical access device includes a single valve that forms a seal with the body wall and provides an access channel into a body cavity. The valve has properties for creating a zero seal in the absence of an instrument as well as an instrument seal with instruments having a full range of instrument diameter. The valve can include a gel and preferably an ultragel comprised of an elastomer and an oil providing elongation greater than 1000 percent and durometer less than 5 Shore A. The single valve can be used as a hand port where the instrument comprises the arm of a surgeon, thereby providing hand access into the cavity. | 2009-05-28 |
20090137880 | Determining the Risk of Breast Cancer for a Woman | 2009-05-28 |
20090137881 | Linked animal-human health visual analytics - Coordinated animal-human health monitoring can provide an early warning system with fewer false alarms for naturally occurring disease outbreaks, as well as biological, chemical and environmental incidents. This monitoring requires the integration and analysis of multi-field, multi-scale and multi-source data sets. In order to better understand these data sets, models and measurements at different resolutions must be analyzed. To facilitate these investigations, we have created an application to provide a visual analytics framework for analyzing both human emergency room data and veterinary hospital data. Our integrated visual analytic tool links temporally varying geospatial visualization of animal and human patient health information with advanced statistical analysis of these multi-source data. Various statistical analysis techniques have been applied in conjunction with a spatio-temporal viewing window. Such an application provides researchers with the ability to visually search the data for clusters in both a statistical model view and a spatio-temporal view. Our interface provides a factor specification/filtering component to allow exploration of causal factors and spread patterns. In this paper, we will discuss the application of our linked animal-human visual analytics (LAHVA) tool to two specific case studies. The first case study is the effect of seasonal influenza and its correlation with different companion animals (e.g., cats, dogs) syndromes. Here we use data from the Indiana Network for Patient Care (INPC) and Banfield Pet Hospitals in an attempt to determine if there are correlations between respiratory syndromes representing the onset of seasonal influenza in humans and general respiratory syndromes in cats and dogs. Our second case study examines the effect of the release of industrial wastewater in a community through companion animal surveillance. | 2009-05-28 |
20090137882 | System and a method for detecting an endemic or an epidemic disease - This system of detecting endemic or epidemic diseases includes an analysis center connected by a computer network to a number of health booths in which health data can be measured and stored with the conditions under which the measurements are taken. The analysis center generates an alert automatically if an endemic or epidemic disease is detected. | 2009-05-28 |
20090137883 | CAPSULE MEDICAL SYSTEM AND BIOLOGICAL INFORMATION ACQUIRING METHOD - A capsule medical system is provided with a capsule medical device to be inserted into a subject, at least one electrode pad having a plurality of receiving electrodes, a receiving electrode switching unit, a control unit for controlling operations of the receiving electrode switching unit, and a position detector. The capsule medical device has a biological information acquiring unit for acquiring biological information of the subject, and a transmitting unit for outputting the biological information from a transmitting electrode through a living body. At least one electrode pad detects the biological information by a plurality of receiving electrodes. The receiving electrode switching unit switches a pair of receiving electrodes among the plurality of receiving electrodes. The position detector detects a position of the capsule medical device inside the subject based on the biological information detected by the electrode pad, and position coordinate data of the plurality of receiving electrodes. | 2009-05-28 |
20090137884 | METHODS AND APPARATUS FOR REPEATED ISCHEMIC CONDITIONING TREATMENT OF HYPERTENSION AND OTHER MEDICAL CONDITIONS - Methods for ischemic conditioning treatments of a chronic medical condition are provided. Baseline disease-related parameters of a patient with a chronic medical condition are measured. Ischemia is induced in the patient by occluding and releasing arterial flow in one or more extremities of the patient. Post-ischemia parameters in the patient are measured. The baseline and post-ischemia parameters are compared to provide an assessment of an ischemic conditioning treatment of a chronic medical condition. The repeated, scheduled delivery of ischemic conditioning provides a beneficial, therapeutic effect on the chronic medical condition. Also provided is a device for pulse oximetry during periods of absent or low pulsatile blood flow including an artificial pulse generator as well as the use of said device in assessment of ischemic conditioning. | 2009-05-28 |
20090137885 | PULSE OXIMETER ACCESS APPARATUS AND METHOD - Access is provided to certain pulse oximetry systems utilizing a keyed sensor and a corresponding locked sensor port of a restricted access monitor. In such systems, the keyed sensor has a key comprising a memory element, and the monitor has a memory reader associated with the sensor port. The monitor is configured to function only when the key is in communications with the locked sensor port, and the memory reader is able to retrieve predetermined data from the memory element. The monitor is accessed by providing the key separate from the keyed sensor, integrating the key into an adapter cable, and connecting the adapter cable between the sensor port and an unkeyed sensor so that the monitor functions with the unkeyed sensor. | 2009-05-28 |
20090137886 | ANALYTE SENSOR - Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system. | 2009-05-28 |
20090137887 | ANALYTE SENSOR - Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system. | 2009-05-28 |
20090137888 | SYSTEM FOR MONITORING OF PATIENTS - A patient monitoring system implemented by a service provider for users via recording a patient's analytes measurements by non-invasively interrogating a skin patch placed upon the patient's skin surface. The system includes an input module to provide a device to measure analytes from a patient, such as a measurement of the blood glucose level. The measurement is shared among a plurality of output devices such as computers, personal digital assistants (PDAs), cellular phones, and pagers that are stationed or held by various users, such as doctors, patients, researchers, pharmacies, labs, and health insurers. In addition, behavioral attributes are recorded and correlated with the analytes measurements to generate a profile. The profile is selectively sent to output devices based on the user profile corresponding to the output device. Also, access to the profile is monitored by a security module that encrypts the profile to prevent access by un-authorized users. | 2009-05-28 |
20090137889 | Subcutaneous Glucose Electrode - A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow “one-point” in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive species of serum or blood. The electrode is preferably layered, with the layers serially deposited within a recess upon the tip of a polyamide insulated gold wire. A first glucose concentration-to-current transducing layer can be overcoated with an electrically insulating and glucose flux limiting layer (second layer) on which, optionally, an immobilized interference-eliminating horseradish peroxidase based film is deposited. An outer layer is preferably biocompatible. | 2009-05-28 |
20090137890 | DEVICES TO MONITOR GLUCOSE LEVELS AND ISCHEMIA - The disclosure relates to systems, methods, and devices for monitoring a patient's blood and cardiac condition. Patients with diabetes oftentimes wear diabetes management equipment (e.g., a glucose monitor, an external insulin pump, or a device having dual functionality). Such patients risk silent myocardial infarction. Herein described is regular cardiac ischemia/infarction monitoring—which if not monitored can lead to (silent) myocardial infarction. Moreover herein described are combined blood monitoring functionality and cardiac condition monitoring functionality via a single device, meaning that the patient is not required to wear additional equipment. Adding this functionality to already-existing equipment is significantly less invasive than requiring a patient to wear one piece of equipment to monitor his/her blood and a second piece of equipment to monitor his/her cardiac condition. This reduction in invasiveness can lead to significantly greater patient participation and compliance, which can improve health and save the lives of many patients. | 2009-05-28 |
20090137891 | PORTABLE ELECTROCARDIOGRAPH WITH A NEUTRAL ELECTRODE - A portable electrocardiograph, characterized in that a clamping cover which tends to close automatically is provided on one end of a housing; a finger hole is provided between the clamping cover and the housing; a lower half of the inner wall of the finger hole is defined on the housing; an upper half of the inner wall of the finger hole is provided on the clamping cover; the lower half of the inner wall is provided with a first electrode; the other end of the housing is provided with a second electrode; and the back face of the housing is provided with a third electrode, in which the first electrode or the third electrode is a neutral electrode. According to the present invention, at least one portion of at least one of the middle finger, the so-called ring finger, and the little finger of the user's hand for grasping the electrocardiograph can contact the neutral electrode, such that the error of the measured result caused by electrical potential fluctuation on the measured person's body can be eliminated. | 2009-05-28 |
20090137892 | SKIN SENSOR DEVICE - The present invention relates to a sensor ( | 2009-05-28 |
20090137893 | ADDING IMAGING CAPABILITY TO DISTAL TIPS OF MEDICAL TOOLS, CATHETERS, AND CONDUITS - One or more scan illuminators and a plurality of light receivers are provided on the distal end of a tool or other component, so that a plurality of images of a site can be provided in response to output signals from the plurality of light receivers. The output signals from the plurality of light receivers are combined to produce an overall image of the site or a plurality of different images from disparate positions. The plurality of images can be viewed separately to produce a stereo or perspective view, or can be produced using different wavebands of light to provide enhanced information about the site that facilitates use of one or more tools or components at the site. The scan illuminator(s) and plurality of light receivers can be configured to be added to an existing tool or component. | 2009-05-28 |
20090137894 | Breast measurement device and bra fitting system - A breast measurement device and method of accurately measuring a bra for a woman by submerging the woman's upper torso in a body of water that allows the buoyancy of each breast to lift and re-conform the breasts to their natural shape. A scanning machine is then used to measure the woman's upper torso and the submerged, lifted breasts to obtain their exact size, volume and location which then can be used to select a properly fitting bra which holds and supports the breasts in their natural position. In the preferred embodiment, the system will include a transparent tank filled with water in which a woman sits upright. A scanning machine then moves around tank and aimed at the woman's upper torso and the breasts. A digital file is then created and stored that is then used to select a proper fitting bra. | 2009-05-28 |
20090137895 | REAL-TIME DIAGNOSTIC SYSTEM EMPLOYING NON-INVASIVE METHOD TO ANALYZE ELECTRO-MAGNETIC FIELD RADIATED FROM A SUBJECT AND THE VARIATION THEREOF - The present invention relates to a real-time disease diagnostic system employing a non-invasive method capable of analyzing of an electromagnetic field and variations thereof radiated from a subject. The disease diagnostic system detects a micro electromagnetic field and variations thereof radiated from bio-action potential of the living tissue, such as cells, tissues, organs and the like of a subject, as a capacitance and variations thereof using a single- or multi-channel biosensor and the disease diagnostic system including the biosensor. The disease diagnostic system analyzes the frequency obtained according to the capacitance and variations thereof and diagnoses proliferative diseases characteristic of an abnormal cell proliferation by diagnosing whole body using a non-invasive method in a short time of 10 min to 1 hour without any side effects. The disease diagnostic system displays the result of diagnosis in the form of a numerical value, sound or three-dimensional image in real time. The disease diagnosis system may be used without any of the doctor's orders for the subject, i.e., an empty stomach or taking medicine, and used to easily confirm the removal of cancer cell by surgery and the process of treatment. Therefore, the disease diagnosis system can be useful to diagnose various diseases at an early stage in a more accurate and safe manner. | 2009-05-28 |
20090137896 | MAGNETIC RESONANCE DEVICE AND METHOD - The invention relates to a device for MR imaging of a body ( | 2009-05-28 |
20090137897 | METHOD FOR MAGNETIC RESONANCE SPECTROSCOPIC IMAGING - A method for performing spectroscopy using an interleaved readout for at least two species. A B | 2009-05-28 |
20090137898 | ARRANGEMENT TO TRANSMIT DIGITAL SIGNALS IN A MAGNETIC RESONANCE APPARATUS - An arrangement for transmission of digital signals in a magnetic resonance apparatus has a local coil that has reception antenna connected via an amplifier with an A/D converter so that a magnetic resonance signal received via the individual antenna is amplified as an analog signal and is converted into a digital signal. The A/D converter is connected at the output with a transmission device that is designed for capacitive coupling transmission of the digital signal. | 2009-05-28 |
20090137899 | Devices, systems, and methods for locating magnetic injection fill ports - Devices, systems, and methods provide accurate and consistent identification of the center of a magnetic infusion port. | 2009-05-28 |
20090137900 | Methods and Apparatus for Locating Body Vessels and Occlusions in Body Vessels - Methods and apparatus employed to locate body vessels and occlusions in body vessels finding particular utility in cardiac surgery, particularly minimally invasive cardiac surgery to locate cardiac arteries and occlusions in cardiac arteries are disclosed. An elongated vessel lumen probe incorporating a lumen probe element at or near the elongated vessel lumen probe distal end is advanced into the vessel lumen. A vessel surface probe manipulated by the surgeon and having a surface probe element sensor is employed to detect the lumen probe element and to follow the progress of the vessel lumen probe element as it approaches and is advanced through or is blocked by an occlusion. In the location of a coronary artery, the surface probe element sensor is moved about against the epicardium over the suspected location of the artery of interest until a surface probe element sensor of the present invention at the surface probe distal end interacts with the lumen probe element of the vessel lumen probe. | 2009-05-28 |
20090137901 | METHOD AND SYSTEM FOR REGISTERIING A MEDICAL SITUATION ASSOCIATED WITH A FIRST COORDINATE SYSTEM, IN A SECOND COORDINATE SYSTEM USING AN MPS SYSTEM - System for registering a first image with a second image, the system including a first medical positioning system for detecting a first position and orientation of the body of a patient, a second medical positioning system for detecting a second position and orientation of the body, and a registering module coupled with a second imager and with the second medical positioning system, the first medical positioning system being associated with and coupled with a first imager, the first imager acquiring the first image from the body, the first imager producing the first image by associating the first image with the first position and orientation, the second medical positioning system being associated with and coupled with the second imager, the second imager acquiring the second image and associating the second image with the second position and orientation, the registering module registering the first image with the second image, according to the first position and orientation and the second position and orientation. | 2009-05-28 |
20090137902 | Intraoperative imaging methods - Described are methods for intraoperative imaging of anatomical structures using fluorescent compounds, e.g., compounds that fluoresce in the invisible light (IL) region of the spectrum, i.e., above 670 nm. An exemplary compound is methylene blue. | 2009-05-28 |