21st week of 2011 patent applcation highlights part 51 |
Patent application number | Title | Published |
20110124805 | LOW VISCOSITY ALLOPHANATES CONTAINING ACTINICALLY CURABLE GROUPS - The present invention relates to a process for preparing radiation-curing binders containing allophanate groups by reacting at temperatures of ≦130° C.
| 2011-05-26 |
20110124806 | DIMENSIONALLY STABLE POLYIMIDES, AND METHODS RELATING THERETO - A film is disclosed, containing 40-100 weight percent polyimide. The polyimide is derived from a dianhydride component and a diamine component. The dianhydride component is at least 3,3′,4,4′-biphenyl tetracarboxylic dianhydride (BPDA), and optionally is also pyromellitic dianhydride (PMDA) in a mole ratio of 50-100:50-0 (BPDA:PMDA). The diamine component comprises 1,5-naphthalenediamine (1,5-ND) and 1,4-diaminobenzene (PPD) and/or meta phenylene diamine (MPD) in a mole ratio of 15-95:85-5 (1,5-ND:PPD+MPD). The films have exceptional high temperature storage modulus (elastic modulus) and exceptionally low high temperature creep (e | 2011-05-26 |
20110124807 | GLYOXAL AND METHYLGLYOXAL AS ADDITIVE FOR POLYMER BLENDS - The present invention relates to a polymer blend, comprising
| 2011-05-26 |
20110124808 | POLYMERIC COMPOUND CONTAINING METAL COMPLEX RESIDUE AND ELEMENT COMPRISING SAME - A polymeric compound containing a residue of a metal complex represented by formula (1) [wherein M represents a metal atom selected from ruthenium, rhodium, palladium, osmium, iridium and platinum; R | 2011-05-26 |
20110124809 | USE OF 2-ISOPROPYL-2-ALKYL-1,3-PROPANEDIOLS FOR PREPARING POLYMERS - Polymer obtainable by polycondensation or polyadduct formation from monomeric compounds, wherein accompanying use is made as monomeric compound of | 2011-05-26 |
20110124810 | MODIFIED POLYACRYLONITRILE FIBER AND METHOD OF PREPARING THE SAME - A modified polyacrylonitrile fiber and its preparation process and use are disclosed. A biological protein is used as a modifier of polyacrylonitrile fiber. The weight content of fiber components is as follows: the acrylonitrile monomer 50.0-98.8%, the initiator 0.1-0.4%, the biological protein 1.0-50.0%. The preparation process of the modified polyacrylonitrile fiber comprises the following steps: 1. preparing the biologic protein solution, 2. preparing spinning dope of the modified polyacrylonitrile fiber, 3. preparing the modified polyacrylonitrile fiber. The filament titer of the modified fiber is 30-100 dtex. The fiber is suitable for making synthetic hair product such as hairpieces, and resembles well natural human hair. | 2011-05-26 |
20110124811 | CURABLE REACTION RESIN SYSTEM - A curable reaction resin system can be used for example as a casting compound, molding compound, or high-temperature resin, and is to be processed as a two-component compound. The system has a first reaction resin component and a second reaction resin component, the first reaction resin component being epoxy-free and realized on the basis of a cyanate ester. | 2011-05-26 |
20110124812 | FIXING MATERIAL COMPRISING SILANE COMPOUND POLYMER AND PHOTONIC DEVICE SEALED BODY - A fixing material includes a silane compound polymer as the main component, the silane compound polymer being produced by condensing a silane compound mixture that includes at least one silane compound (1) shown by the following formula (1): R | 2011-05-26 |
20110124813 | RUBBER-REINFORCED VINYL AROMATIC POLYMERS - Rubber-reinforced vinyl aromatic polymers having a strictly bimodal morphology, comprising from 55 to 90% by weight of a rigid polymeric matrix and from 10 to 45% by weight of a rubbery phase dispersed inside said rigid polymeric matrix, in the form of grafted and occluded particles and wherein said rubber particles consist of from 60 to 99% by weight of particles with a capsule or “core-shell” morphology and from 1 to 40% by weight of particles with a “salami” morphology, said percentages being measured on the basis of the weight of the rubber particles only. | 2011-05-26 |
20110124814 | Thermoset Compositions with Dispersed Thermoplastic Resin Therein and Process for Making Them - A rubber composition comprising: a cured rubber; and thermoplastic resin, where the thermoplastic resin is in the form of discrete domains dispersed within a continuous phase of the cured rubber, and where the cured rubber includes silicon-containing crosslinks. | 2011-05-26 |
20110124815 | POLYURETHANE AND PRODUCTION METHOD THEREOF - The invention relates to polyurethane having s excellent electric insulating property and thermal stability, obtained by a polyaddition reaction between a polyol copolymer which is a copolymer comprising as monomer units the structures represented by formulae (1) and (2) and a polyisocyanate compound: | 2011-05-26 |
20110124816 | FLUORORESIN FILM AND FLUORORESIN-LAMINATED ACRYLIC RESIN FILM - An object of the present invention is to provide a novel monolayer and multilayer film that can be employed also for use in interior and exterior members of vehicles, and that have excellent transparency, surface hardness, chemical resistance, and stain resistance such as lactic acid resistance and sunscreen resistance. The present invention is directed to a fluororesin film formed with (C) a fluororesin comprising (B) a fluorinated (meth)acrylic resin that contains a fluorine-containing alkyl(meth)acrylate polymer component; and a fuororesin-laminated acrylic resin film, wherein the fluororesin film layer is laminated on at least one face of a film layer comprising (A) an acrylic resin. | 2011-05-26 |
20110124817 | Molded Polymeric Article with Low Haze and High Clarity - The present disclosure provides a molded article composed of a polymeric composition and processes for producing the same. The polymeric composition includes from about 60 wt % to about 99 wt % of a matrix of a propylene-based polymer. The propylene-based polymer has a refractive index (n1). The polymeric composition also includes from about 40 wt % to about 1 wt % of elongated elastomer particles dispersed in the propylene-based polymer. The elongated elastomer particles have a refractive index (n2). The propylene-based polymer and the elongated elastomer particles exhibit a refractive index mismatch whereby |n1−n2|>0.002. The molded article has a haze value less than about 20% and optionally a viscosity ratio (VR) greater than 0.28. | 2011-05-26 |
20110124818 | Catalyst Composition Comprising Shuttling Agent for Ethylene Multi-Block Copolymer Formation - A composition for use in forming a multi-block copolymer, said copolymer containing therein two or more segments or blocks differing in chemical or physical properties, a polymerization process using the same, and the resulting polymers, wherein the composition comprises the admixture or reaction product resulting from combining:
| 2011-05-26 |
20110124819 | MODIFIED HALOGENATED POLYMER SURFACES - Disclosed is a method of preparing a modified halogenated polymer surface, comprising the steps of (a) activating the surface by modification with a polymerisation initiator by (a | 2011-05-26 |
20110124820 | SUPRAMOLECULAR STRUCTURE OF HAVING SUB-NANO SCALE ORDERING - Provided is a crystalline organic polymer in which a main chain formed of amorphous polymer or monomer having a functional group is combined with a side chain by quaternization, cross-linking, hydrogen bonding or organic material-metal interaction. The main chain material having a functional group is combined with the side chain material to have crystallinity, and the organic polymer having crystallinity exhibits excellent diode characteristics. | 2011-05-26 |
20110124821 | PROCESS FOR MAKING POLYBUTYLENE TEREPHTHALATE (PBT) FROM POLYETHYLENE TEREPHTHALATE (PET) - In one embodiment, the invention relates to a two step process in which a 1,4-butane diol component reacts with a polyethylene terephthalate component under conditions that depolymerize the polyethylene terephthalate component into a molten mixture and the molten mixture is placed under subatmospheric conditions that produce the modified polybutylene terephthalate random copolymers. In another embodiment, the invention relates to a three step process in which a diol component selected from the group consisting of ethylene glycol, propylene glycol, and combinations thereof reacts with a polyethylene terephthalate component under conditions sufficient to depolymerize the polyethylene terephthalate component into a first molten mixture; and where the first molten mixture is combined with 1,4-butane diol under conditions that create a second molten mixture that is subsequently placed under subatmospheric conditions that produce the modified polybutylene terephthalate random copolymers. The invention also relates to compositions made from processes of the invention. | 2011-05-26 |
20110124822 | SEMICONDUCTING POLYMERS - Novel Semiconducting photovoltaic polymers with conjugated units that provide improved solar conversion efficiency that can be used in electro-optical and electric devices. The polymers exhibit increased solar conversion efficiency in solar devices. | 2011-05-26 |
20110124823 | SOLVENT-FREE CROSSLINKED POLYROTAXANE MATERIAL AND PROCESS FOR PRODUCTION OF SAME - A material comprising crosslinked polyrotaxanes which exhibits desired viscoelasticity, particularly stress-strain characteristics with a wide low-stress region, in spite of being free from solvent; and a process for production of the same. The material comprises a first polyrotaxane bearing first cyclic molecules and a second polyrotaxane bearing second cyclic molecules, and the first and second polyrotaxanes are crosslinked via the first and second cyclic molecules. The material is free from solvent and exhibits a stress of 2.0 MPa or below at 50% strain. | 2011-05-26 |
20110124824 | DISPERSION COMPOSITION, POLYMERIZABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER, SOLID-STATE IMAGE PICK-UP ELEMENT, LIQUID CRYSTAL DISPLAY DEVICE, WAFER LEVEL LENS, AND IMAGE PICK-UP UNIT - A dispersion composition is provided in which the dispersibility of titanium black is high, the sedimentation of titanium black over time is suppressed, and overall dispersibility and storage stability are high. Further, a polymerizable composition is provided in which favorable coating property on a substrate and even film thickness can be obtained, generation of residue in an unexposed region when a pattern is formed can be suppressed, and favorable pattern shape having any steps after exposure/development can be obtained. The dispersion composition contains (A) titanium black, (B) a graft copolymer and (C) a solvent. | 2011-05-26 |
20110124825 | Production Process of Poly(Arylene Sulfide) Whose Content of Terminal Halogen Group Has Been Reduced - The invention provides a production process of a poly(arylene sulfide) which contains a step of polymerizing a sulfur source and a dihalo-aromatic compound in an organic amide solvent, said polymerization step containing a phase-separation polymerization step that the polymerization reaction is continued in the presence of a phase separation agent in a phase-separated state, wherein a monohalo-organic compound is added in a proportion of 0.005 to 20 mol per 100 mol of the charged sulfur source into the polymerization reaction system at the time a conversion of the dihalo-aromatic compound has reached 80 to 99% after initiation of the polymerization reaction and before the liquid phase becomes the phase-separated state to be reacted with a formed polymer, and the liquid phase within the polymerization reaction system is then converted to the phase-separated state to continue the polymerization reaction. | 2011-05-26 |
20110124826 | METHOD OF USING AN UPPER DISCHARGE IN A FLUIDIZED BED REACTOR AND SYSTEM THEREOF - A method according to one embodiment includes operating a reactor or providing a reactor after operation, wherein the reactor includes a bottom section, a bed section above the bottom section, a distributor plate between the bottom section and the bed section, an expanded section above the bed section, and an upper section above the bed section, wherein the bed section has a height H measured from the distributor plate to the expanded section; measuring a concentration of particulates in the upper section of the reactor to obtain a first determined level of particulates in the upper section; and discharging at least some of the particulates from the reactor at an upper discharge point located above 0.55H as measured vertically from the distributor plate based on the first determined level. Additional systems and methods are also provided. | 2011-05-26 |
20110124827 | Oligomerisation of Olefins - In the oligomerisation of olefins in a tubular reactor employing a molecular sieve catalyst, the temperature of the reaction is monitored and the space velocity of the olefin feed to the reactor is reduced as the temperature increases. This has been found to increase catalyst life and lead to extended production runs. Further extensions of the production run are achieved by improving reactor operating stability as the end of the production run approaches. | 2011-05-26 |
20110124828 | Loop Reactor Suitable for Olefin Polymerization with Improved Product Removal Means - The present invention relates to a loop reactor suitable for olefin polymerization process comprising:
| 2011-05-26 |
20110124829 | SYNTHESIS OF ACRYLIC OR METHACRYLIC ACID/ACRYLATE OR METHACRYLATE ESTER POLYMERS USING PERVAPORATION - Products and processes relating to the synthesis of copolymers or terpolymers are described. In particular, poly(acrylic acid-co-acrylate ester), poly(methacrylic acid-co-methacrylate ester), poly(acrylic acid-co-acrylate ester(I)-co-acrylate ester(II)), or poly(methacrylic acid-co-methacrylate ester(I)-co-methacrylate ester(II)), by esterification of polyacrylic or polymethacrylic acid with alcohols assisted by the pervaporation technique for extracting water are described. | 2011-05-26 |
20110124830 | HYDROGENATED BETA-PINENE-BASED POLYMERS AND MOLDED ARTICLES COMPRISING THE SAME - The present invention provides hydrogenated β-pinene-based polymers with excellent heat resistance and light resistance, low absorptivity and high transparency, as well as molded articles thereof. The polymers of the present invention contain 50% by mass or more of β-pinene units and are hydrogenated β-pinene-based polymers where the ratio of the proton integral value at 6 to 8 ppm to the total proton integral value in a | 2011-05-26 |
20110124831 | SELF-ASSEMBLED OLEFIN POLYMERIZATION CATALYST - The present invention relates to a self-assembled olefin polymerization catalyst comprising a transition metal compound according to formula (I) L | 2011-05-26 |
20110124832 | NOVEL LIVING RADICAL POLYMERIZATION METHOD USING ALCOHOL AS CATALYST - Provided is a low-cost, environmentally friendly living radical polymerization catalyst having high activity. The catalyst is used for a living radical polymerization method, and contains a central element consisting of oxygen and at least one halogen atom bound to the central element. Furthermore, an alcohol compound can be used as a catalyst precursor. By polymerizing a monomer in the presence of the catalyst, a polymer having narrow molecular weight distribution can be obtained, and the cost of the living radical polymerization can be remarkably reduced. The present invention is significantly more environmentally friendly and economically excellent than conventional living radical polymerization methods, due to advantages of the catalyst such as low toxicity of the catalyst, low amount of the catalyst necessary, high solubility of the catalyst, mild reaction conditions, and no coloration/no odor (which do not require a post-treatment for a molded article), and the like. | 2011-05-26 |
20110124833 | MEDICAL PRESSURE-SENSITIVE ADHESIVE COMPOSITION - There is provided a medical pressure-sensitive adhesive composition including an acrylic copolymer obtained by copolymerizing monomer components containing (a) at least one kind of a monomer of a (meth)acrylic acid alkyl ester and (b) at least one kind of a monomer of an N-hydroxyalkyl(meth)acrylamide, wherein: a content of the (meth)acrylic acid alkyl ester monomer (a) with respect to a total amount of the monomer components is 50 weight % to 99.9 weight % and a content of the N-hydroxyalkyl(meth)acrylamide monomer (b) with respect to the total amount is 0.1 weight % to 20 weight %; and the monomer components are substantially free of a monomer having a carboxyl group. The medical pressure-sensitive adhesive composition of the present invention is particularly suitable for applications such as medical patches and patch preparations. | 2011-05-26 |
20110124834 | PROCESS FOR STARTING UP A SEPARATING PROCESS FOR PURIFYING REMOVAL OF ACRYLIC ACID CRYSTALS FROM A SUSPENSION S OF CRYSTALS THEREOF IN MOTHER LIQUOR - A process for starting up a separating process for purifying removal of acrylic acid crystals from a suspension S of crystals thereof in mother liquor with a hydraulic wash column which has a crystal melt circuit including crystal melt space, and a process space and a distributor space which are separated by an end with passages connecting the two spaces, in which the crystal bed is formed for the first time by first filling the crystal melt circuit and, at least partly, the process space with an acrylic acid-comprising startup liquid whose acrylic acid crystal formation temperature is less than or equal to the temperature of the suspension S increased by 15° C., and then continuing the filling of the wash column with the suspension S and optionally with control liquor until the difference between the pressure in the crystal melt space and the pressure in the distributor space falls suddenly, the arithmetic mean of the total waste liquor flow flowing through the filters of the filter tubes of the wash column until this time, based on the area of all filters, being not more than 80 m | 2011-05-26 |
20110124835 | METHOD FOR MANUFACTURING HIGH MOLECULAR WEIGHT POLYETHYLENE FIBERS - A process for manufacturing high molecular weight polyethylene fibers, including subjecting a polyethylene tape with a weight average molecular weight of at least 500,000 grams/mole, a Mw/Mn ratio of at most 6, and a 200/110 uniplanar orientation parameter of at least 3 to a force in the direction of the thickness of the tape over the entire width of the tape. A polyethylene fiber having a Mw of at least 500 000 gram/mole, a Mw/Mn ratio of at most 6, and a 020 uniplanar orientation value of at most 55°. | 2011-05-26 |
20110124836 | COMPOSITION, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL COMPONENT, AND METHOD FOR PRODUCING THE COMPOSITION - The composition of the present invention contains a product having a thiol group obtained by reacting an Sb or Bi oxide or an Sb or Bi halide with at least one kind of polythiol compounds selected from compounds having at least two thiol groups in a molecule. | 2011-05-26 |
20110124837 | Polymeric Violet Anthraquinone Colorant Compositions and Methods For Producing the Same - This invention relates to polymeric violet anthraquinone colorants having at least one poly(oxyalkylene) chain attached to an anthraquinone structure. Such colorants exhibit bright violet shade, excellent compatibility with organic media or aqueous systems, good lightfastness, and excellent thermal stability. The water soluble poly(oxyalkylene) substituted polymeric violet anthraquinone colorants also possess high water solubility, high color strength, non-staining properties, and high pH stability. The processes and methods for making such polymeric violet anthraquinone colorants and their use for coloring consumer products are also provided. | 2011-05-26 |
20110124838 | METHOD FOR PRODUCTION TONER, TONER, AND METHOD FOR RECYCLING PAPER - The present invention provides a method for producing a toner, which includes 1) saccharifying paper by at least one of a chemical degradation method and a biochemical degradation method to obtain a sugar-containing solution, 2) subjecting the sugar-containing solution obtained through 1) to lactic acid fermentation to obtain a lactic acid, 3) polymerizing the lactic acid obtained through 2) to obtain a polylactic acid, and 4) producing a toner using the polylactic acid obtained through 3). | 2011-05-26 |
20110124839 | FLAME-RETARDANT POLYESTER COPOLYMER, AND PRODUCTION PROCESS AND MOLDED ARTICLE THEREOF - The invention provides a production process of a flame-retardant polyester copolymer, having a first step of adding a catalyst to a 2,5-furan dicarboxylic acid compound, an aliphatic or alicyclic diol, itaconic acid and 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide to obtain an oligomer, and a second step of adding a catalyst to the oligomer obtained in the first step to conduct polycondensation, thereby obtaining the flame-retardant polyester copolymer. | 2011-05-26 |
20110124840 | Synthesis of Homopolymers and Block Copolymers - The present invention relates to the field of polymer chemistry and more particularly to homopolymers and block copolymers and methods of preparing the same. | 2011-05-26 |
20110124841 | Polypeptides Modified by Protein Trans-Splicing Technology - The present invention relates to a method of preparing modified polypeptides, by linking a target polypeptide to a carrier molecule that is designed to bear one or more water-soluble polymer molecules, via protein trans-splicing. The polymer molecules can be attached to the carrier molecule either before or after ligation to the target polypeptide. Novel protein trans-splicing elements (known as “split inteins”) and trans-splicing partners are also provided. | 2011-05-26 |
20110124842 | Peptide that binds to a broadly neutralizing anti-HIV antibody-structure of 4E10 Fab fragment complex, uses thereof, compositions therefrom - The present invention relates to the structure of Fab 4E10, e.g., as a complex with herein identified peptide KGND, herein identified as a 4E10 mimetope on gp41, as determined by crystallographic techniques, and the confirmation that peptide KGND has a functional relevant conformation, as well as the determination of key residues on 4E10, and uses thereof and compounds and compositions therefrom. Furthermore, the invention also relates to other peptides and mimetic peptides which bind to Fab 4E10. | 2011-05-26 |
20110124843 | METHOD FOR EFFICIENTLY AMPLIFYING ABNORMAL PRION PROTEIN DERIVED FROM BSE - A method for efficiently amplifying abnormal prion protein (PrP | 2011-05-26 |
20110124844 | Selective and Specific Preparation of Discrete Peg Compounds - Aspects of the present invention are directed to novel methods for making discrete polyethylene compounds selectively and specifically to a predetermined number of ethylene oxide units. Methods which can be used to build up larger dPEG compounds (a) containing a wider range of utility to make useful homo- and heterofunctional and branched species, and (b) under reaction configurations and conditions that are milder, more efficient, more diverse in terms of incorporating useful functionality, more controllable, and more versatile then any conventional method reported in the art to date. In addition, the embodiments of the invention allow for processes that allow for significantly improving the ability to purify the intermediates or final product mixtures, making these methods useful for commerial manufacturing dPEGs. Protecting groups and functional groups can be designed to make purification at large scale a practical reality. The novel dPEG products form the compositional and material basis for making other novel compounds of valuable application in the fields of diagnostics and therapeutics, amongst others. | 2011-05-26 |
20110124845 | PROCESS FOR PROTEIN EXTRACTION - The invention includes a process for extracting a target protein from | 2011-05-26 |
20110124846 | CELLULOSIC AND LIGNOCELLULOSIC STRUCTURAL MATERIALS AND METHODS AND SYSTEMS FOR MANUFACTURING SUCH MATERIALS - Methods of treating wood and wood products include irradiating untreated wood having a first molecular weight with ionizing radiation to cause an increase in the molecular weight of a cellulosic component of the wood to a second, relatively higher molecular weight. | 2011-05-26 |
20110124847 | METHOD FOR PREPARING CONCRETE WATER REDUCER BY GRAFTING OF LIGNOSULFONATE WITH CARBONYL ALIPHATICS - The present invention disclosed a concrete water reducer by grafting of lignosulfonate with carbonyl aliphatics and its preparation method. A technical solution of the method is as follows: compound proportioning of the concrete water reducer (weight) is: carbonyl group aliphatics:lignosulfonate=1:(0.75-1). The said concrete water reducer by grafting of lignosulfonate with carbonyl aliphatics is prepared through following process steps: controlling the temperature of aliphatics water reducer at 95-100° C.; dropping lignosulfonate into said aliphatics water reducer; conducting graft copolymerization reaction at 95° C.-100° C. for 2-5 h and obtaining lignosulfonate modified and grafted aliphatics concrete water reducer. The method of present application is simple, low cost and friendly to environment. The water reducer has good water reducing effect and can reduce colour aberration of concrete and thus be applied broadly. | 2011-05-26 |
20110124848 | METALLOFULLERENE CONTRAST AGENTS - Endohedral metallofullerene compounds, which in water has a relaxivity of about 30 mM | 2011-05-26 |
20110124849 | AZO DYE - An azo dye represented by the following formula (I): | 2011-05-26 |
20110124850 | Glycorandomization and Production of Novel Vancomycin Analogs - The present invention provides glycorandomized structures and combinatorial methods for rapidly generating a diverse library of glycorandomized structures, comprising incubating one or more aglycons and a pool of NDP-sugars in the presence of a glycosyltransferase. The glycosyltransferase may be one that is associated with or involved in production of natural secondary metabolites, or one which is putatively associated with or involved in production of natural secondary metabolites. The glycosyltransferase may show significant flexibility with respect to its NDP-sugar donors and/or its aglycons. NDP-sugar donors may be commercially available, or may be produced by utilizing mutant or wild type nucleotidyltransferases significant flexibility with respect to their substrates. | 2011-05-26 |
20110124851 | Method of Isolation of Nucleic Acids - A method of isolation of nucleic acids from a biological sample of cells comprising a combination of a solid phase cell nuclei isolation procedure with a solid phase nucleic acid isolation method. | 2011-05-26 |
20110124852 | MOLECULAR MARKERS FOR IDENTIFICATION OF FAT AND LEAN PHENOTYPES IN CHICKENS - The invention provides molecular methods of screening chickens to determine those more likely to have a lean or fat phenotype by identifying the presence of at least one polymorphism in genetic material of a chicken in the thyroid hormone repressible gene (THRG) or its 3′ untranslated region (SEQ ID NO: 1) that is associated with a fat phenotype or a lean phenotype. The invention also provides methods of screening chickens to identify a polymorphism associated with a fat or lean phenotype. The invention further provides oligonucleotide probes and primers useful for detecting the polymorphisms associated with a fat or lean phenotype. | 2011-05-26 |
20110124853 | Conjugates and Compositions for Cellular Delivery - This invention features conjugates, degradable linkers, compositions, methods of synthesis, and applications thereof, including cholesterol, folate, galactose, galactosamine, N-acetyl galactosamine, PEG, phospholipid, peptide and human serum albumin (HSA) derived conjugates of biologically active compounds, including antibodies, antivirals, chemotherapeutics, peptides, proteins, hormones, nucleosides, nucleotides, non-nucleosides, and nucleic acids including enzymatic nucleic acids, DNAzymes, allozymes, antisense, dsRNA, siNA, siRNA, triplex oligonucleotides, 2,5-A chimeras, decoys and aptamers. | 2011-05-26 |
20110124854 | Cosmetic composition containing one or more compounds of the Beta-(1,3)-glucuronan or Beta-(1,3)-glucoglucuronan type - The invention relates to a cosmetic composition that contains one or more compounds of the β-(1,3)-glucuronane or β-(1,3)-glucoglucuronane type as well as the pharmaceutically acceptable salt thereof, and to the use of this composition and these compounds for various cosmetic applications. | 2011-05-26 |
20110124855 | METHOD FOR ISOLATION OF LAUROLACTAM FROM A LAUROLACTAM SYNTHESIS PROCESS STREAM - A process for purifying laurolactam by means of integrated connection of distillation and crystallization is provided. The crystallization is performed as a solution or melt crystallization. The process reduces thermal stress applied to the laurolactam stream and improved yields are obtained. Raw materials are recovered and recycled in the production sequence. | 2011-05-26 |
20110124856 | AMINOPROPYLIDENE DERIVATIVE - An aminopropylidene derivative having excellent histamine receptor antagonistic action, a compound which is useful as a pharmaceutical composition, especially as an active ingredient, having alleviated side effects in the central nervous system is described. In the aminopropylidene derivative, R | 2011-05-26 |
20110124857 | ARTHROPODICIDAL ANTHRANILAMIDES - This invention provides compounds of Formula 1, their N-oxides and agriculturally suitable salts | 2011-05-26 |
20110124858 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND PEST CONTROL AGENT - The present invention relates to a nitrogen-containing heterocyclic compound or salt thereof, represented by the following formula (I), and a pest control agent containing the compound or salt thereof, as an active ingredient of the pest control agent: | 2011-05-26 |
20110124859 | PROCESS FOR THE MANUFACTURING OF BETAMIMETICS - The present invention relates to a process for preparing betamimetics of formula 1, | 2011-05-26 |
20110124860 | PROCESS FOR THE SYNTHESIS OF 3,6-DIHYDRO-1,3,5-TRIAZINE DERIVATIVES - A new process for the synthesis of 3,6-dihydro-1,3,5-triazine derivatives for the treatment of disorders associated with insulin-resistance syndrome. | 2011-05-26 |
20110124861 | Process for Preparing Pemetrexed Disodium and Its Intermediate, 4-(4-Carbomethoxyphenyl) Butanal - The present invention provides a process for preparing pemetrexed disodium and its intermediate, 4-(4-carbomethoxyphenyl)butanal. The process for preparing the intermediate comprises the following steps: condensing methyl 4-bromobenzoate with 3-buten-1-ol; extracting with an organic solvent during the work-up; adding silica gel to decolorize; and evaporating the organic solvent to give 4-(4-carbomethoxyphenyl)butanal. The product obtained by the present process, with a yield of higher than 80%, and a purity measured by GC of higher than 95%, may be directly used in the next bromination reaction for synthesizing pemetrexed disodium without purification. The present process is suitable for industrial production, as the operation is simple and the reagents used are cheap and readily available. | 2011-05-26 |
20110124862 | PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH A CYCLIC AMINO GROUP AS CRF ANTAGONISTS - [Problem to be Solved] An object of the present invention is to provide an antagonist against CRF receptors and/or an agonist for δ receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastrointestinal diseases, drug dependence, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alopecia, irritable bowel syndrome, sleep disorders, epilepsy, dermatitides, schizophrenia, pain, etc. | 2011-05-26 |
20110124863 | PROCESS TO PREPARE PALIPERIDONE AND INTERMEDIATES THEREOF - The present invention relates to an improved process for obtaining Paliperidone, I, comprising alkylating compound VI, or a salt thereof, with compound V, or a salt thereof, using a base selected from triethylamine or diisopropylethylamine and, optionally, a solvent. Moreover, the invention relies on the preparation of intermediates used in such process. | 2011-05-26 |
20110124864 | PREPARATION METHOD OF ROSUVASTATIN CALCIUM AND ITS INTERMEDIATES - A preparation method of rosuvastatin calcium (Formula 1), which can be used for the production of medicament lowering the levels of LDL-cholesterol and triglycerides in vivo, is provided. Such preparation method is suitable for industrial production. Furthermore, the intermediate crystallines used in the preparation method are provided. | 2011-05-26 |
20110124865 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PHENYLALANINES - Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds are disclosed. | 2011-05-26 |
20110124866 | PROCESS FOR PREPARATION OF TADALAFIL - Process for the preparation of tadalafil of high pharmaceutical purity is characterized in that the sequence of reactions comprising acetylation of methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate with chloro acetyl chloride and cyclisation of the formed intermediate with methyl amine, is performed as a ‘one-pot’ process, without isolating the intermediate methyl (1R,3R)-1-(1,3-benzodioxol-5-yl)-2-(chloroacetyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate. | 2011-05-26 |
20110124867 | Process and intermediates for the Synthesis of heterocyclic Substituted Piperazines with CXCR3 Antagonist Activity - The present invention relates to novel processes for the preparation of the compound of the Formula A45: | 2011-05-26 |
20110124868 | RUTHENIUM OLEFIN METATHESIS CATALYSTS BEARING N-HETEROCYCLIC CARBENE LIGANDS WITH SUBSTITUTED BACKBONE - This invention relates generally to olefin metathesis, more particularly, to tri- or tetra-substituted imidazolinium salts which are precursors to N-heterocyclic carbene (NHC) ligands with tri- or tetra-substituted imidazolinium rings, organometallic ruthenium complexes comprising gem di-substituted imidazolinium NHC ligands, organometallic ruthenium complexes comprising tri- or tetra-substituted imidazolinium NHC ligands, and to olefin metathesis methods using them. The catalysts and methods of the invention have utility in the fields of catalysis, organic synthesis, and industrial chemistry. | 2011-05-26 |
20110124869 | Process for Preparing Modulators of Cystic Fibrosis Transmembrane Conductance Regulator - The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith. | 2011-05-26 |
20110124870 | NOVEL MYCOBACTERIAL INHIBITORS - The present invention relates to novel substituted quinoline derivatives according to the general Formula (Ia) or the general Formula (Ib) | 2011-05-26 |
20110124871 | ARTHROPODICIDAL ANTHRANILAMIDES - This invention provides compounds of Formula 1, their N-oxides and agriculturally suitable salts | 2011-05-26 |
20110124872 | DERIVATIVES OF PRYIDONE AND USE THEREOF - The present invention provides N-substituted-2(1H) pyridones or the pharmaceutical acceptable salts thereof, and the pharmaceutical preparations containing the compounds. The compounds of the present invention can be used to treat various fibrotic diseases effectively, e.g., hepatic fibrosis. | 2011-05-26 |
20110124873 | Bis(perfluoralkyl)phosphinous acids and derivatives and use thereof - The invention relates to bis(perfluoroalkyl)phosphinous acids, bis(perfluoroalkyl)thiophosphinous acids and derivatives, the synthesis thereof and the use thereof, in particular for the synthesis of air-stable metal complexes for catalytic processes. | 2011-05-26 |
20110124874 | IMINOPYRIDINE DERIVATIVES AND USE THEREOF - The present invention aims to provide an iminopyridine derivative compound having an α | 2011-05-26 |
20110124875 | IMINOPYRIDINE DERIVATIVES AND USES THEREOF - The present invention aims to provide an iminopyridine derivative compound having an α | 2011-05-26 |
20110124876 | IMINOPYRIDINE DERIVATIVES AND USE THEREOF - The present invention aims to provide an iminopyridine derivative compound having an α | 2011-05-26 |
20110124877 | 5-BENZYL-4-AZOLYLMETHYL-4-SPIRO[2.4]HEPTANOL DERIVATIVES, METHODS FOR PRODUCING THE SAME, AND AGRO-HORTICULTURAL AGENTS AND INDUSTRIAL MATERIAL PROTECTING AGENTS THEREOF - To provide a novel 5-benzyl-4-azolylmethyl-4-spiro[2.4]heptanol derivative, a method for producing the same, and an agro-horticultural agent and an industrial material protecting agent containing as an active ingredient the abovementioned 5-benzyl-4-azolylmethyl-4-spiro[2.4]heptanol derivative. | 2011-05-26 |
20110124878 | KINASE INHIBITORS AND METHODS OF USE THEREOF - A compound of Formula II | 2011-05-26 |
20110124879 | STABLE AMORPHOUS FORM OF CARVEDILOL DIHYDROGEN PHOSPHATE WITH STABILIZER - The present invention provides a novel stable amorphous form of carvedilol dihydrogen phosphate and the process for its preparation that involves reaction of carvedilol base with ortho phosphoric acid in the presence of stabilizer in a suitable solvent or mixture of solvents followed by concentration and isolation. An alternate process for preparation of amorphous form of carvedilol dihydrogen phosphate involves addition of stabiliser to the solution of stable amorphous or crystalline carvedilol dihydrogen phosphate in a suitable solvent or mixture of solvents followed by concentration and isolation. The novel stable amorphous form of carvedilol dihydrogen phosphate is highly stable. | 2011-05-26 |
20110124880 | COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES - Disclosed herein are non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of possible functionalities, but typical have at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Also disclosed herein are non-natural amino acid polypeptides that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such polypeptides. Typically, the modified non-natural amino acid polypeptides include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Further disclosed are methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses. | 2011-05-26 |
20110124881 | PROCESS OF FORMING A PYRROLE COMPOUND - Disclosed is a process of forming a pyrrole compound. The process comprises contacting an α-carbonyl oxime compound 1 | 2011-05-26 |
20110124882 | Method for Preparing N-Substituted Maleimides - The present invention relates to a method of preparing N-substituted maleimide in high purity and high yield, wherein, unlike a conventional method of preparing N-substituted maleimide after preparing N-substituted maleamic acid, an organic solvent, an acid catalyst, a dehydration co-catalyst and a stabilizer are added into a reactor without separately preparing N-substituted maleamic acid, and then a primary amine is added into the reactor to form an amine salt, maleic anhydride is added into the reactor, and the resulting mixture is subjected to a dehydration-cyclization reaction, wherein water produced during the reaction is azeotropically distilled with the organic solvent so as to effectively suppress formation of a maleimide polymer. Particularly, the invention simplifies the process, has high yield, minimizes side reactions, eliminates the introduction of expensive raw materials and the complicated treatment of the reaction solution and significantly shortens the time over which the raw materials and maleic anhydride are added. | 2011-05-26 |
20110124883 | METHOD OF PREPARING SULTINES - A method of preparing a sultine from a dihalogeno compound. The method comprises the steps of reacting the dihalogeno compound with a hydroxymethanesulfinate salt in a DMSO solvent so as to prepare the sultine. | 2011-05-26 |
20110124884 | PROCESS FOR PRODUCING THIOPHENE COMPOUND AND INTERMEDIATE THEREOF - To provide a novel process for producing a 2-aryl-3-hydroxy-4-substituted carbonyl thiophene compound or an intermediate thereof useful as an intermediate for production of medicines and agricultural chemicals. | 2011-05-26 |
20110124885 | MULTILAYER CATALYST HAVING VANADIUM ANTIMONATE IN AT LEAST ONE CATALYST LAYER FOR PREPARING CARBOXYLIC ACIDS AND/OR CARBOXYLIC ANHYDRIDES AND PROCESS FOR PREPARING PHTHALIC ANHYDRIDE HAVING A LOW HOT SPOT TEMPERATURE - The present invention relates to a catalyst system for preparing carboxylic acids and/or carboxylic anhydrides, which system comprises a plurality of superposed catalyst layers arranged in a reaction tube, where vanadium antimonate is introduced into the active material in at least one of the catalyst layers. The present invention further relates to a process for gas-phase oxidation, in which a gaseous stream comprising at least one hydrocarbon and molecular oxygen is passed through a plurality of catalyst layers and the maximum hot spot temperature is below 425° C. | 2011-05-26 |
20110124886 | PROCESS FOR THE PREPARATION OF DISPIRO 1,2,4-TRIOXOLANE ANTIMALARIALS (OZ277) - This invention relates to an improved process for the preparation of a compound of Formula (I), salts of the free base cis-adamantane-2-spiro-3′-8′-[[[(2′-amino-2′-methyl propyl)amino]carbonyl]methyl]-1′,2′,4′-trioxaspiro[4.5]decane wherein X can be an anion. | 2011-05-26 |
20110124887 | EPIGALLOCATECHIN DIMERS OR TRIMERS HAVING LIPASE INHIBITORY ACTIVITY AND/OR ANTIOXIDANT ACTIVITY - An object of the present invention is to provide a lipase activity inhibitor that shows high inhibitory activity against pancreatic lipase to suppress the absorption of meal-derived fat and/or which contributes to suppressing and preventing obesity, as well as a food or beverage that has such lipase activity inhibitor incorporated therein. Another object of the invention is to provide a lipase inhibitor of tea origin that suits most consumers' taste and which will not impair the flavor of the food or beverage when incorporated therein. Still another object of the invention is to provide a process for producing said lipase inhibitors. Further object of the invention is to provide antioxidants. To attain these objects, epigallocatechin dimers (oolong homobisflavans) or trimers are incorporated in foods or beverages. As a result, the absorption of meal-derived fat can be suppressed and, in addition, antioxidation effect is obtained. The compounds of the invention can be produced by reacting epigallocatechin gallate with formaldehyde in the presence of an acid. | 2011-05-26 |
20110124888 | STYRYLBENZOFURAN DERIVATIVES AS INHIBITORS FOR BETA-AMYLOID FIBRIL FORMATION AND PREPARATION METHOD THEREOF - The present invention relates to a novel compound which efficiently inhibits the formation of beta-amyloid fibrils in the brain to be useful for preventing or treating a degenerative brain disease, a method for preparing same, and a pharmaceutical composition comprising same as an active ingredient. | 2011-05-26 |
20110124889 | Process for the oxidation of alcohol and/or aldehyde groups - A process for the oxidation of alcohol and/or aldehyde groups with a peroxo compound in the presence of a heterogeneous rhenium based catalyst, and a co-catalyst. The process of the invention may, for example, be applied to the manufacture of maleic acid which can be dehydrated to lead to maleic anhydride. | 2011-05-26 |
20110124890 | BATCH, SEMI-CONTINUOUS OR CONTINUOUS HYDROCHLORINATIONOF GLYCERIN WITH REDUCED VOLATILE CHLORINATED HYDROCARBON BY-PRODUCTS AND CHLOROACETONE LEVELS - The present invention relates to a process for converting a multihydroxylated-aliphatic hydrocarbon or ester thereof to a chlorohydrin, by contacting the multihydroxylated-aliphatic hydrocarbon or ester thereof starting material with a source of hydrogen chloride at superatmospheric, atmospheric and subatmospheric pressure conditions for a sufficient time and at a sufficient temperature, preferably wherein such contracting step is carried out without substantial removal of water, to produce the desired chlorohydrin product; wherein the desired product or products can be made in high yield without substantial formation of undesired overchlorinated byproducts; said process carried out without a step undertaken to specifically remove volatile chlorinated hydrocarbon by-products or chloroacetone, wherein the combined concentration of volatile chlorinated hydrocarbon by-products and chloroacetone is less than 2000 ppm throughout any stage of the said process. | 2011-05-26 |
20110124891 | ALPHA-PENTAFLUOROSULFANYL ALDEHYDES, KETONES AND ACIDS - Compounds of formula (I): are disclosed. In these compounds Y is —CH(OH)—, —CH(NHR | 2011-05-26 |
20110124892 | BATCH, SEMI-CONTINUOUS OR CONTINUOUS HYDROCHLORINATIONOF GLYCERIN WITH REDUCED VOLATILE CHLORINATED HYDROCARBON BY-PRODUCTS AND CHLOROACETONE LEVELS - The present invention relates to a process for converting a multihydroxylated-aliphatic hydrocarbon or ester thereof to a chlorohydrin, by contacting the multihydroxylated-aliphatic hydrocarbon or ester thereof starting material with a source of hydrogen chloride at superatmospheric, atmospheric and subatmospheric pressure conditions for a sufficient time and at a sufficient temperature, preferably wherein such contracting step is carried out without substantial removal of water, to produce the desired chlorohydrin product; wherein the desired product or products can be made in high yield without substantial formation of undesired overchlorinated byproducts; said process carried out without a step undertaken to specifically remove volatile chlorinated hydrocarbon by-products or chloroacetone, wherein the combined concentration of volatile chlorinated hydrocarbon by-products and chloroacetone is less than 2000 ppm throughout any stage of the said process. | 2011-05-26 |
20110124893 | ANTIBIOTIC COMPOUNDS - The present invention relates to the new crystalline solid form XI of Tigecycline and a process of preparing the same. Form XI of Tigecycline is particularly suitable for the isolation of Tigecycline in the last step of the synthesis of Tigecycline. Further the present invention relates to a process of preparing amorphous Tigecycline by spray drying form XI or another crystalline form of Tigecycline. | 2011-05-26 |
20110124894 | METHOD FOR OBTAINING LONG CHAIN ALIPHATIC ALCOHOLS AND FATTY ACIDS FROM SUGAR CANE MUD AND RELATED WAX ESTERS - Methods are provided for the extraction of wax esters from sugar cane mud, isolation of the wax, saponification of the wax, either after isolation or in an intermediate un-isolated form to provide higher primary aliphatic alcohols (HPAA's) and fatty acids having nutritional and medicinal uses. The solid waste resulting from the process can be disposed of or utilized as a soil substitute following an optional water wash. Additionally, methods are provided for providing modified forms of the sugar cane mud or cachaza having reduced volumes and/or water content that require less storage space and capable of being stored for long periods of time with little or no biological degradation. | 2011-05-26 |
20110124895 | Method of purifying interesterified oils - [Problems] To provide a method of purifying interesterified oils, which is capable of efficiently purifying the interesterified oil through a series of steps effectively solving a problem of decreased oxidation stability of the interesterified oil that is purified and a problem of color tone. | 2011-05-26 |
20110124896 | A 9,10,12-TRIACYLOXY OCTADECANOIC ACID ALKYL ESTER AND 9,10,12-TRIACYLOXY OCTADECANOIC ACID ALKYL ESTER RICH FATTY ACID ALKYL ESTERS MIXTURE AND A PROCESS FOR PREPARATION THEREOF - The present invention relates to modification of the chemical structure of ricinoleic acid, which is present to an extent of 85-90% in castor oil into triacyloxy alkyl ester derivatives. Accordingly, 9,10,12-trihydroxy octadecanoic acid rich fatty acid mixture was prepared from castor oil and converted to their alkyl esters followed by acylation of hydroxy groups to get 9,10,12-triacyloxy octadecanoic acid alkyl ester rich fatty acid alkyl esters mixture. The 9,10,12-triacyloxy octadecanoic acid alkyl esters were purified from the crude product and characterized by | 2011-05-26 |
20110124897 | Process for Refining a Triglyceride Oil - A process for refining a triglyceride oil comprises:—providing a triglyceride oil;—bleaching the oil in the presence of an added antioxidant in a first bleaching step;—bleaching the oil in a second bleaching step; and—deodorizing the bleached oil, wherein the antioxidant comprises a rosemary extract. | 2011-05-26 |
20110124898 | CHEMICAL AND METHOD FOR CHELATING METAL IONS INCLUDED IN WATER AND SEPARATING/RECOVERING OF FORMED CHELATE - The present invention relates to a chemical for chelation of metal ions, which are at least bivalent, contained in water and/or water enclosed objects and separation/recovering of formed chelate; the structural formula of which is formula (I) where R in at least one of the positions shown is comprised of a group in the form of a straight or branched hydrocarbon chain having from 9 to 20 carbon atoms, and where appropriate 1-2 hetero atoms, and which is missing in other position (s); and where X in shown positions is in a group in the form of —COOH or its salt; and wherein the chemical can be a racemate, a mixture of enantiomers, or pure enantiomers or where R is missing in all four positions shown X in at least one position is —COOR, —CONHR or CH | 2011-05-26 |
20110124899 | METHOD FOR PREPARING COMBRETASTATIN - The Invention relates to a method for preparing a combretastatin (A): formula (I) in the form of a base or of an addition salt with an acid, which comprises coupling, in the presence of a base and of T3P, the salt of the (Z)-amino compound of formula (II) with a doubly protected L-serine derivative of formula (III) in which PG denotes a group protecting the amine function, so as to obtain the compound of formula (Z)-(Ib): formula (IV), then deprotecting and opening the ring of (Z)-(Ib) in the presence of an acid, so as to obtain the combretastatin (A) in the form of a salt; and, optionally, adding a base, so as to obtain the combretastatin (A) in the form of a base, the salt of the (Z)-amino compound having been obtained by enrichment of the salt of the amino compound of formula (V) in (Z) isomer. | 2011-05-26 |
20110124900 | DIARYL ALKYLPHOSPHONATES AND METHODS FOR PREPARING SAME - A method for preparing substantially pure optionally substituted diaryl alkylphosphonates from an optionally substituted triarylphosphite and an optionally substituted trialkylphosphite or an optionally substituted alkanol under special reaction conditions is described. | 2011-05-26 |
20110124901 | HIGH-YIELD PRODUCTION OF ORGANIC NITRILES - A process is disclosed for producing organic nitriles such as Acetonitrile or Hydrogen Cyanide, in which yields may exceed 90%, undesirable by-products are not produced, and handling of ammonia gas is avoided. In one aspect, a process includes preparing a feed including ammonium salts and water; introducing the feed into a reactor containing a catalyst; and heating the feed in the presence of the catalyst. The catalyst may advantageously include molybdenum on a silica or silica alumina support. The feed may be ammonium acetate in water with about 50 wt % ammonium acetate and the balance water or ammonium formate in water. In another aspect, a process includes preparing a feed including ammonium hydroxide and acetic acid; introducing the feed into a reactor containing a catalyst; and heating the feed in the presence of the catalyst. | 2011-05-26 |
20110124902 | PREPARATION OF CARBAMATES WITH SOLID CATALYSTS - Carbamate preparation process comprising, the reaction between at least:
| 2011-05-26 |
20110124903 | SOLID STATE FORMS OF FESOTERODINE INTERMEDIATES - Provided herein are novel solid state forms of fesoterodine intermediates, (R)-4-benzyloxy-3-(3-diisopropylamino-1-phenylpropyl)-benzoic acid and (R)-[4-benzyloxy-3-(3-diisopropylamino-1-phenylpropyl)-phenyl]-methanol, and processes for their preparation thereof. The solid state intermediates are useful for preparing fesoterodine or a pharmaceutically acceptable salt thereof in high purity. | 2011-05-26 |
20110124904 | Allyl acetate hydroformylation process - A process for the production of 4-acetoxybutyraldehyde is described. The process comprises reacting allyl acetate with a mixture of carbon monoxide and hydrogen in the presence of a solvent and a catalyst comprising a rhodium complex and a diphosphine. The diphoshine is a substituted or unsubstituted 2,2′-bis(dihydrocarbylphosphino)diphenyl ether. The process gives a high ratio of 4-acetoxybutyraldehyde:3-acetoxy-2-methylpropionaldehyde. | 2011-05-26 |