21st week of 2012 patent applcation highlights part 46 |
Patent application number | Title | Published |
20120129213 | Multi-Spectral Imaging Including At Least One Common Stain - A method including: providing a sample with M components to be labeled, where M>2; labeling the components with N stains, where N2012-05-24 | |
20120129214 | PEPTIDE SYNTHESIS USING ENZYMATIC ACTIVATION AN COUPLING - Method for enzymatically synthesising a peptide, comprising enzymatically preparing an ester or a thioester from (i) an N-terminal protected amino acid, an N-terminal protected amino acid C-terminal ester, an N-terminal protected peptide, or an N-terminal protected peptide C-terminal ester and (ii) an alcohol represented by the formula HO—CX | 2012-05-24 |
20120129215 | Compositions of Orthogonal Lysyl-tRNA and Aminoacyl-tRNA Synthetase Pairs and Uses Thereof - Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal lysyl-tRNAs, orthogonal lysyl-aminoacyl-tRNA synthetases, and orthogonal pairs of lysyl-tRNAs/synthetases, which incorporate homoglutamines into proteins are provided in response to a four base codon. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with homoglutamines using these orthogonal pairs. | 2012-05-24 |
20120129216 | ENZYMATIC ANTIBODY PROCESSING - The current invention comprises a method for producing an immunoglobulin or immunoglobulin fragment with defined glycostructure comprising the following steps: a) providing an affinity chromatography column eluate containing the immunoglobulin or immunoglobulin fragment, b) incubating the affinity chromatography column eluate with (α1,3)galactosidase of plant origin, e.g. from green coffee beans (EC 3.2.1.22), c) applying the incubated affinity chromatography column eluate to a protein A chromatography material and recovering the immunoglobulin or immunoglobulin fragment from the protein A chromatography material and thereby producing an immunoglobulin or immunoglobulin fragment with defined glycostructure. | 2012-05-24 |
20120129217 | POLYPEPTIDE EXPRESSION IN CILIATES - This invention is directed to methods for recombinant polypeptide production and, in particular, methods and products for the production of recombinant polypeptides in ciliates. | 2012-05-24 |
20120129218 | COFILIN KNOCKDOWN HOST CELLS AND USES THEREOF - The present invention relates to a host cell comprising a cofilin-specific small interfering RNA (siRNA) sequence. The host cell may further comprise a nucleic acid encoding a recombinant protein. The present invention also relates to a method for producing a recombinant protein by the host cell comprising a cofilin-specific small interfering RNA (siRNA) sequence. | 2012-05-24 |
20120129219 | Antibody Molecules Which Bind Human IL-17 - The invention relates to antibody molecules having specificity for antigenic determinants of IL-17, therapeutic uses of the antibody molecules and methods of producing the antibody molecules. | 2012-05-24 |
20120129220 | PROCESS FOR PRODUCTION OF USEFUL SUBSTANCE, AND SURFACTANT FOR USE IN THE PROCESS - The present invention is aimed to provide a method for industrially producing a useful substance (protein etc.) utilizing a bacterium such as | 2012-05-24 |
20120129221 | BIOCHEMICAL PLATFORM FOR FUELS AND CHEMICALS PRODUCTION FROM CELLULOSIC BIOMASS - An alternative biochemical process for fuels and chemicals production from cellulosic biomass is presented. The method includes an aerobic step where microorganisms convert carbohydrates contained in cellulosic biomass into sugar acids, which can be converted to fuels and chemicals, including ethanol, gluconate, and acetic acid, via fermentation. | 2012-05-24 |
20120129222 | MUTANT FORMATE DEHYDROGENASE, GENE ENCODING THE SAME, AND METHOD FOR PRODUCING NADH - Durability of formate dehydrogenase is improved with the use of formate dehydrogenase exhibiting high specific activity that is unpredictable from conventional findings. A specific amino acid substitution is introduced into | 2012-05-24 |
20120129223 | DNA LOADED SUPPORTED GOLD NANOPARTICLES, PROCESS FOR THE PREPARATION AND USE THEREOF - The present invention relates to DNA loaded gold nanoparticles embedded in sharp carbonaceous carriers useful for higher DNA delivery efficiently into plants. These nanogold embedded carbon matrices are prepared by heat treatment of biogenic intracellular gold nanoparticles. The DNA delivery efficiency is tested on model plants. These materials reveal good dispersion of the transport material, producing a greater number of GUS foci per unit area. The added advantages of the composite carrier are the lower plasmid and gold requirements. Plant cell damage with the prepared carbon supported particles is very minimal and can be gauged from the increased plant regeneration and transformation efficiency compared to that of the commercial micrometer sized gold particles. This can be attributed to the sharp edges that the carbon supports possess, which lead to better piercing capabilities with minimum damage. | 2012-05-24 |
20120129224 | Method and apparatus for changing one type of cell into another type of cell - A method and apparatus converts host cells of a first type into cells of a second type when the host cells are placed in intimate contact with donor cells of the second type. Under predetermined conditions there is transport of a sufficient number of mRNA molecules from the donor cells into the host cells to reprogram the host cells into the second type. The host and donor cells may be subjected to while in intimate contact to a transporting force that enables the mRNA molecules of the donor cells to penetrate an outer membrane wall of host cells without damaging the membrane wall. The transporting force may include an electric field, a magnetic field, or a combined electric field and magnetic field. | 2012-05-24 |
20120129225 | METHODS AND REAGENTS FOR MOLECULAR CLONING - The present invention provides compositions, methods, and kits for covalently linking nucleic acid molecules. The methods include a strand invasion step, and the compositions and kits are useful for performing such methods. For example, a method of covalently linking double stranded (ds) nucleic acid molecules can include contacting a first ds nucleic acid molecule, which has a topoisomerase linked to a 3′ terminus of one end and has a single stranded 5′ overhang at the same end, with a second ds nucleic acid molecule having a blunt end, such that the 5′ overhang can hybridize to a complementary sequence of the blunt end of the second nucleic acid molecule, and the topoisomerase can covalently link the ds nucleic acid molecules. The methods are simpler and more efficient than previous methods for covalently linking nucleic acid sequences. | 2012-05-24 |
20120129226 | TRICHODERMA REESEI ALPHA-AMYLASE IS A MALTOGENIC ENZYME - A maltogenic a-amylase from | 2012-05-24 |
20120129227 | THERMOSTABLE CELLULASES, AND MUTANTS THEREOF, CAPABLE OF HYDROLYZING CELLULOSE IN IONIC LIQUID - The present invention provides for a composition comprising an ionic liquid and a thermostable cellulose, and a method of hydrolyzing a cellulose, comprising: (a) providing a composition comprising a solution comprising an ionic liquid and a cellulose, and (b) introducing a thermostable cellulase to the solution, such that the cellulose is hydrolyzed by the cellulase. The present invention also provides for a | 2012-05-24 |
20120129228 | BACTERIAL CELLULOSE BASED 'GREEN' COMPOSITES - ‘Green’ composites are fabricated using resins, such as soy-based resins, and reinforced with crystalline high strength bacterial cellulose (BC) fibers. Bacterial cellulose is produced by providing a bacterial cellulose-producing bacterium such as | 2012-05-24 |
20120129229 | Yeast Expressing Cellulases for Simultaneous Saccharification and Fermentation Using Cellulose - Host cells, comprising | 2012-05-24 |
20120129230 | Genetically Modified Yeast of the Species Issatchenkia Orientalis and Closely Related Species, and Fermentation Processes Using Same - Cells of the species | 2012-05-24 |
20120129231 | ENGINEERING OF THERMOTOLERANT BACILLUS COAGULANS FOR PRODUCTION OF D(-)-LACTIC ACID - Genetically modified microorganisms having the ability to produce D(−)-lactic acid at temperatures between 30° C. and 55° C. are provided. In various embodiments, the microorganisms may have the chromosomal lactate dehydrogenase (ldh) gene and/or the chromosomal acetolactate synthase (alsS) gene inactivated. Exemplary microorganisms for use in the disclosed methods are | 2012-05-24 |
20120129232 | POLYHYDROXYALKANOATE PRODUCTION FROM POLYOLS - Organisms are provided which express enzymes such as glycerol dehydratase, diol dehydratase, acyl-CoA transferase, acyl-CoA synthetase β-ketothiolase, acetoacetyl-CoA reductase, PHA synthase, glycerol-3-phosphate dehydrogenase and glycerol-3-phosphatase, which are useful for the production of PHAs. In some cases one or more of these genes are native to the host organism and the remainder are provided from transgenes. These organisms produce poly(3-hydroxyalkanoate)homopolymers or co-polymers incorporating 3-hydroxypropionate or 3-hydroxyvalerate monomers wherein the 3-hydroxypropionate and 3-hydroxyvalreate units are derived from the enzyme catalysed conversion of diols. Suitable diols that can be used include 1,2-propanediol, 1,3 propanediol and glycerol. Biochemical pathways for obtaining the glycerol from normal cellular metabolites are also described. The PHA polymers are readily recovered and industrially useful as polymers or as starting materials for a range of chemical intermediates including 1,3-propanediol, 3-hydroxypropionaldehyde, acrylics, malonic acid, esters and amines. | 2012-05-24 |
20120129233 | METHOD FOR PRODUCING AN ORGANIC ACID - An organic acid is produced by allowing a bacterium belonging to the family Enterobacteriaceae, which has an ability to produce an organic acid and has been modified so that the phosphoenolpyruvate carboxykinase activity is enhanced, and the glucose phosphotransferase activity is decreased, which is selected from | 2012-05-24 |
20120129234 | SYSTEM FOR TREATMENT OF BIOMASS TO FACILITATE THE PRODUCTION OF ETHANOL - A method for treating fermented lignocellulosic biomass to be supplied to a distillation system for production of ethanol is provided. The method includes pre-treating lignocellulosic biomass into pre-treated biomass and separating the pre-treated biomass into a liquid component comprising sugars and a solids component comprising cellulose and lignin. The method also includes hydrolysing the solids component of the pre-treated biomass into a hydrolysed biomass comprising sugars and lignin and fermenting the hydrolysed solids component of the pre-treated biomass into a fermentation product comprising ethanol and lignin. The method also includes treating the fermentation product and distilling the treated fermentation product to recover the ethanol. The lignocellulosic biomass comprises cellulose, hemi-cellulose and lignin. | 2012-05-24 |
20120129235 | Novel fragrance and methods for production of 5-EPI- - vetivone,2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one, and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one - The present invention is directed to novel methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethylspiro[4.5]deca-1,6-dien-8-one, which are useful for their fragrant qualities. Provided are methods for production of premnaspirodiene from a terpene substrate, methods for production of 5-epi-β-vetivone from premnaspirodiene as starting material, and methods for production of 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one from premnaspirodiene as starting material. | 2012-05-24 |
20120129236 | FORMULATION AND PROCESS FOR CO2 CAPTURE USING AMINO ACIDS AND BIOCATALYSTS - A formulation and a process for CO | 2012-05-24 |
20120129237 | POLYNUCLEOTIDES ENCODING NOVEL PCSK9 VARIANTS - The present invention provides novel polynucleotides encoding PCSK9b and PCSK9c polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel PCSK9b and PCSK9c polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention. | 2012-05-24 |
20120129238 | REVERSE TRANSCRIPTASE MIXTURES WITH IMPROVED STORAGE STABILITY - Reverse transcriptase mixtures with improved storage stability are provided. | 2012-05-24 |
20120129239 | HOMOLOGOUS RECOMBINATION-BASED DNA CLONING COMPOSITIONS - Methods and compositions for cloning a donor DNA molecule into an acceptor vector at a predetermined location are described. The methods are based on homologous recombination mediated by in vitro treatment of the donor DNA and the acceptor vector with an enzyme cocktail containing an exonuclease and a single-stranded DNA binding protein. | 2012-05-24 |
20120129240 | BUFFER COMPOUNDS - A method of buffering a chemical or biological composition, comprising adding to the composition an effective buffering amount of at least one protonated or un-protonated amine-quaternary ammonium compound having a general formula: | 2012-05-24 |
20120129241 | AN L-ARABINOSE FERMENTING YEAST - An L-arabinose utilizing yeast strain is provided for the production of ethanol by introducing and expressing bacterial araA, araB and araD genes. L-arabinose transporters are also introduced into the yeast to enhance the uptake of arabinose. The yeast carries additional genomic mutations enabling it to consume L-arabinose, even as the only carbon source, and to produce ethanol. A yeast strain engineered to metabolize arabinose through a novel pathway is also disclosed. Methods of producing ethanol include utilizing these modified yeast strains. | 2012-05-24 |
20120129242 | Falling Film Evaporator - An apparatus and method are disclosed for controlling the thickness of a flowing, laminar fluid film. The film flow may be gravity-induced or the result of an alternative force. The fluid is deposited on an upper end of a flow surface where a relatively thick layer of the film forms. The film flows over a fluid dispersal region where the surface area is rapidly expanding, which results in rapid thinning of the film thickness. The fluid then flows over an active region where the surface area is designed to control the fluid film thickness. For example, in some applications, it may be desirable to maintain an approximately constant film thickness as the fluid flows over the active region of the surface. The geometry of the flow surface is used to obtain the desired control over the fluid film thickness. The flow surface is the outer surface of a solid with a closed upper end and a lower end that may be open or closed. An open lower end allows for injection of a heated material, which may be used to heat the solid surface. This process may be used to heat the fluid flow surface so that evaporation of the flowing fluid results. A falling film evaporator is one application of the disclosed invention. A carbon capture system using a thin, flowing algae film is another application. Other potential uses of the invention are disclosed as well. | 2012-05-24 |
20120129243 | Algae Producing Trough System - A trough lining assembly is placed in a series of troughs at a biomass processing facility. The trough lining assembly includes a waterproof liner that lies against the sides of a trough, an aerator, and a retention mechanism that retains the aerator at the bottom of the trough. The aerator provides continuous aeration of biomass present in the trough by releasing aerating gas into the biomass along the length of the trough. The continuous aeration also churns the biomass, exposing more of it to the aerating gas and to sunlight. The trough lining assembly improves the efficiency of algae production by stimulating photosynthesis and consumption of carbon dioxide. The trough lining assembly has low production, transportation, installation, and maintenance costs. | 2012-05-24 |
20120129244 | SYSTEMS, METHODS AND APPARATUSES FOR DEWATERING, FLOCCULATING AND HARVESTING ALGAE CELLS - Described herein are systems, methods and apparatuses, for dewatering, flocculating and harvesting microorganisms. In various implementations, at least one intracellular product from the microorganisms is recovered and processed according to methods disclosed herein. In some implementations, an electromagnetic field is applied to an aqueous suspension of microorganisms thereby causing flocculation of the microorganisms. In various implementations, the microorganisms are harvested, such as by causing the microorganisms to flocculate and sink to the bottom of a container. Alternatively, the microorganisms are caused to flocculate and float to the surface of the aqueous medium where they can be recovered by skimming. In other implementations, the microorganisms are lysed as they are passed through a second electromagnetic field to release intracellular products, among other desired components of the microorganisms. In some implementations, the intracellular contents of the microorganisms, as well as cellular mass and debris, are recovered and utilized as useful products. | 2012-05-24 |
20120129245 | ALGAE REACTOR - The invention relates to a lighting system for illuminating algae in an aqueous liquid. The lighting system includes a light source comprising a plurality of LEDs, a mounting structure for supporting the LEDs and a housing for accommodating the light source and the mounting structure. At least a portion of the housing is transparent for light emitted by the light source. The housing is at least partly filled with a cooling liquid, such that, in use, heat from the LEDs is transferred by the cooling liquid from the LEDs by means of convection. The invention further relates to a reactor comprising such lighting system. | 2012-05-24 |
20120129246 | FORMULATION AND PROCESS FOR CO2 CAPTURE USING CARBONATES AND BIOCATALYSTS - A formulation and process for capturing CO | 2012-05-24 |
20120129247 | SAMPLE ANALYZER - A sample analyzer for analyzing a sample with a liquid in a container is disclosed. The sample analyzer comprises: a reader that reads an information of a liquid in a container, the information of the liquid being stored in a storage medium; a display; and a controller including a processor and a memory under control of the processor, the memory storing instruction causing the processor to carry out operations comprising: determining whether the sample analyzer is ready to read the information of the liquid by the reader; and causing, when the sample analyzer is determined to be ready, the display to display an indication that indicates the sample analyzer is ready to read the information of the liquid by the reader. | 2012-05-24 |
20120129248 | ASSAY TOOLS AND METHODS OF USE - The present invention provides assay tools for the detection of biological or chemical activity in a sample. The assay tools of the invention provide direct detection using a positive signal generated on a surface of the assay tool. These assay tools provide improved methods for detection and/or identification of multiple agents (e.g., enzymes) in a sample, analysis of substrate specificity of such agents, and binding affinities and specificities of such agents. Upon activity a component is released from a first immobilised construct and then captured by a capture surface. At least two different immobilised constructs are used. | 2012-05-24 |
20120129249 | STIRRING APPARATUS FOR STIRRING MICROORGANISMS IN A CULTURING MEDIUM - The invention provides a stirring apparatus for stirring microorganisms such as, an alga in a culturing medium. The stirring apparatus includes one or more supporting structures. The stirring apparatus further includes a plurality of paddle units operatively connected to the one or more supporting structures. The plurality of paddle units are submerged in the culturing medium holding the microorganisms. Further, the plurality of paddle units are configured to rotate for stirring the microorganisms in the culturing medium. In response to the rotation of the plurality of paddle units, the stirring apparatus propels in the culturing medium. | 2012-05-24 |
20120129250 | MICROTITRATION PLATE - A microtitration plate, having a frame made of a plastic which has a plate with a multiplicity of holes, and a multiplicity of receptacles made of the same plastic which are fixedly connected to the plate at the holes by directly molding them thereto, have a receiving portion protruding from the underside of the plate, and are accessible from the upper surface of the plate through apertures. | 2012-05-24 |
20120129251 | METHOD FOR DEPARAFFINIZING FORMALIN-FIXED PARAFFIN-EMBEDDED TISSUE - The invention provides a method for deparaffinizing a formalin-fixed paraffin-embedded tissue, including: providing a formalin-fixed paraffin-embedded tissue sample; mixing the formalin-fixed paraffin-embedded tissue sample with an organic solvent and water or with an organic solvent and an aqueous solution to form a mixture, wherein a density of the organic solvent is less than that of the water or the aqueous solution, and the organic solvent is immiscible with the water or the aqueous solution; and separating the mixture into an organic solution layer and an aqueous solution layer, wherein a paraffin dissolved from the formalin-fixed paraffin-embedded tissue sample is in the organic solution layer and a deparaffinized tissue from the formalin-fixed paraffin-embedded tissue sample is in the aqueous solution layer and/or an interlayer between the organic solution layer and the aqueous solution layer. | 2012-05-24 |
20120129252 | METHOD AND SYSTEM FOR CELL FILTRATION - Methods and systems disclosed in the present application include membrane-like filters and methods and systems that employ these membrane-like filters to isolate circulating tumor cells and other abnormal cells from biological fluids, such as blood. The disclosed methods and systems use membrane-like filters that include a pattern or array of small, tapered apertures fabricated within a relatively thin but mechanically robust polymeric material that resists accumulation of biological-solution components and clogging during filtration of biological solutions. | 2012-05-24 |
20120129253 | ADIPOSE TISSUE-DERIVED STROMAL CELLS AND METHODS OF ISOLATING AND USING THE SAME - Adipose tissue-derived stromal cells and methods of isolating and using the same. In at least one embodiment of isolated adipose tissue-derived stromal cells of the present disclosure, the cells are isolated by performing adipose tissue resection or suction on a mammalian patient, dissecting tissue obtained from said tissue resection or suction and dissociating said tissue into a cell suspension, removing adipocytes from the cell suspension, culturing the adipocyte-depleted cell suspension in EGM-2-MV media, and isolating adipose tissue-derived stromal cells secreting vascular endothelial growth factor (VEGF), hepatocyte growth factor (HGF), and granulocyte-colony stimulating factor (G-CSF). | 2012-05-24 |
20120129254 | Inducible Expression System Transcription Modulators Comprising A Distributed Protein Transduction Domain And Methods For Using The Same - Aspects of the invention include inducible expression systems in which a transcription modulator having a distributed protein transduction domain is employed. Aspects of the invention further include methods of using the systems to induce expression of a coding sequence, as well as kits that find use in practicing methods of the invention. The systems, components thereof, methods and kits find use in a variety of different applications. | 2012-05-24 |
20120129255 | FUNCTIONALIZATION OF SILK MATERIAL BY AVIDIN-BIOTIN INTERACTION - The present invention provides for compositions and methods of linking silk fibroin to active agents through the specific interaction between avidin and biotin, providing for functionalization of silk-based protein biomaterials. An avidin- or biotin-modified silk is a biomaterial platform for functionalization with a variety of correspondingly linked active agents, such as antibodies and growth factors. A variety of functionalized silk materials, such as silk hydrogel, silk micro/nanoparticles and silk films, can be prepared by the methods of the present invention. The functionalization strategies of the present invention are relatively easy, fast and feasible, and are thus useful in many biomedical applications. | 2012-05-24 |
20120129256 | METHOD OF PREPARING PLURIPOTENT STEM CELLS - The invention relates to biotechnology, and particularly to the preparation of pluripotent stem cells. The method involves introduction into umbilical cord and placental stem cells of RNA with at least one sequence which ensures the transition of cells to the pluripotent state. The method enables to effectively prepare pluripotent stem cells from the cells of mammalian placenta and umbilical cord which have not yet acquired somatic mutations, which reduces the risk of oncogenesis and other adverse effects of reprogramming. | 2012-05-24 |
20120129257 | Apparatus For Culturing Anchorage Dependent Cells - The invention relates to an apparatus ( | 2012-05-24 |
20120129258 | CELL CHIP AND METHOD OF FABRICATING THE SAME - Disclosed herein are a cell chip and a method of fabricating the same. The cell chip includes a cell-adhesivecell-adhesive layer disposed on a substrate. Photocrosslinked polymer barriers are disposed on the cell-adhesivecell-adhesive layer. The photocrosslinked polymer barriers may serve to restrict and grow cells only on the cell-adhesivecell-adhesive layer exposed between the barriers. Therefore, a cell growth direction may be precisely controlled. In addition, the photocrosslinked polymer barrier has a pattern formed by light, and simplifies a process of fabricating a cell chip. | 2012-05-24 |
20120129259 | METHOD FOR PRODUCING A COATED CELL CULTURE CARRIER - The present invention relates to a method for producing a coated cell culture carrier, wherein a solution comprising a polyurethane urea is applied to a cell carrier and dried. The polyurethane urea is produced beforehand by converting at least one polycarbonate polyol component, at least one polyisocyanate component, and at least one diamino component. The invention further relates to a cell culture carrier obtained according to the method and the use thereof for in-vitro cultivation of stem cells, particularly for cultivating mesenchymal stem cells. | 2012-05-24 |
20120129260 | METHOD FOR PRODUCING PLURIPOTENT STEM CELLS - Methods are provided for producing a human embryo capable of developing to the blastocyst stage. The method includes transferring a human somatic cell genome into a mature human oocyte by nuclear transfer and activating the oocyte, without removing the oocyte genome. Pluripotent human embryonic stem cells, and methods of obtaining these, are also provided. | 2012-05-24 |
20120129261 | Transcriptome Transfer Produces Cellular Phenotype Conversion - The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome. | 2012-05-24 |
20120129262 | Methods of Modifying Transcriptional Regulatory Networks in Stem Cells - The vast differentiation potential of human embryonic and induced pluripotent stem cells, including their potential to cascade through all of the somatic cell lineages and to display the complete transcriptional regulatory network of human biology, has generated interest in deriving scalable, purified, and identified cell types and methods of discovering the precise structure of the human regulatory network. However, the innate capacity of pluripotent cells to display all these lineages is not necessarily reflected during their culture in vitro. The clonal isolation and propagation of progenitors greatly facilitates the generation of highly purified and identified formulations for research and therapeutic purposes. Nevertheless, other cell types have yet to be isolated and propagated from normal cells and methods of isolating said novel cell types as well as methods for introducing perturbations into the transcriptional regulatory network in order to construct a computer model of the entire human transcriptional regulatory network would greatly benefit basic research as well as manufacturing technology for cell-based therapies. | 2012-05-24 |
20120129263 | RECOMBINANT VIRAL VECTOR FOR GENE TRANSFER INTO LYMPHOID CELLS - A recombinant herpesvirus, a method for producing the recombinant herpesvirus, and a pharmaceutical composition comprising the recombinant herpesvirus, are provided with a method for producing a recombinant herpesvirus using a BAC vector sequence. In addition, a vector comprising a herpesvirus genomic gene and a BAC vector sequence, a cell comprising the vector, and a nucleic acid cassette comprising a fragment, which is capable of homologous recombination with a herpesvirus genome, and a BAC vector sequence, are provided. | 2012-05-24 |
20120129264 | Method for Transforming a Bacterium Belonging to the Streptococcus Genus by Natural Competence - The present invention relates to peptides, nucleic acids and methods for transforming a bacterium belonging to the | 2012-05-24 |
20120129265 | NEW BIOMARKERS FOR ASSESSING KIDNEY DISEASES - The present invention relates to a metabolic biomarker set for assessing kidney disease comprising at least two amino acids, at least two acylcarnitines and at least two biogenic amines. Moreover, the present invention relates to a method for assessing kidney disease in a mammalian subject which comprises obtaining a biological sample, preferably blood and/or urine, from the subject and measuring in the biological sample the amount of at least two amino acids, of at least two acylcarnitines and of at least two biogenic amines, as well as to a kit adapted to carry out the method. By employing the specific biomarkers and the method according to the present invention it becomes possible to more properly and reliably assess kidney disease. | 2012-05-24 |
20120129266 | METHOD OF DETECTING OXIDES OF NITROGEN - The present disclosure provides methods and kits to detect and quantitate NOx compounds in a biological sample. The methods include reacting a mixture comprising a nitrite compound a chromogenic reagent to form a colored compound, contacting the mixture with a retention medium configured to retain the colored compound, and detecting the colored compound retained on the retention medium. | 2012-05-24 |
20120129267 | SULFUR BREAKTHROUGH DETECTION ASSEMBLY FOR USE IN A FUEL UTILIZATION SYSTEM AND SULFUR BREAKTHROUGH DETECTION METHOD - A sulfur breakthrough monitoring assembly for use in a fuel utilization system for detecting sulfur-containing compounds in desulfurized fuel, said monitoring assembly comprising: a heater for heating desulfurized fuel to a predetermined temperature, the predetermined temperature being between 450° C. and 600° C., a sulfur breakthrough detector adapted to receive heated fuel from the heater and including at least a reforming catalyst bed for reforming the heated fuel and a plurality of temperature sensors including a first temperature sensor for sensing temperature of the heated fuel before the fuel is conveyed through the reforming catalyst bed and a second temperature sensor for sensing temperature in the reforming catalyst bed, and a controller for determining whether concentration of the sulfur-containing compounds in the fuel exceeds a first predetermined concentration based on temperature outputs from the first and second temperature sensors. | 2012-05-24 |
20120129268 | PHOTOLUMINESCENT OXYGEN PROBE WITH REDUCED CROSS-SENSITIVITY TO HUMIDITY - An oxygen-sensitive luminescent element, and probe constructed therefrom, having reduced cross-sensitivity to humidity, and methods of manufacturing and using such luminescent elements and probes to measure oxygen concentrations within an enclosed space. The luminescent element includes a glass fiber carrier substrate bearing an oxygen-sensitive photoluminescent dye. The dye is preferably embedded within an oxygen-permeable hydrophobic polymer matrix. A probe is constructed from the luminescent element by laminating the luminescent element onto a structural support layer. | 2012-05-24 |
20120129269 | NANO-OPTIC FILTER ARRAY BASED SENSOR - A device such as a filter or reflector includes a conductive layer including a periodic pattern of elements. The elements have shapes and sizes configured such that a transmittance or reflectance spectrum of the conductive layer has a drop at a long-wavelength end. The elements have a period configured such that the spectrum has a dip at a Plasmon mode resonant wavelength. The spectrum further includes a peal- between the dip and the drop. | 2012-05-24 |
20120129270 | VESICULAR SYSTEM AND USES THEREOF - Disclosed is a vesicular system comprising a surface with a vesicle immobilized thereon. The immobilized vesicle has a circumferential membrane of an amphiphilic polymer. The vesicle is coupled to a surface by means of a molecule with a non-polar moiety. The non-polar moiety comprises a main chain of 3 to about 30 carbon atoms and 0 to about 12 heteroatoms selected from Si, O, S, and Se. The molecule with the non-polar moiety is coupled to the surface via a covalent or non-covalent bond. A portion of the non-polar moiety is integrated in the circumferential membrane. | 2012-05-24 |
20120129271 | LONGITUDINAL ASSAY - Embodiments of the invention relate generally to macro and small molecule detection and, more particularly, to methods for detecting macro and small molecules, including bio-molecules, in a liquid or gaseous sample. Methods according to embodiments of the invention are useful in the identification, discovery, and validation of biomarkers, as well as the screening of individuals for such biomarkers for diagnostic, therapeutic, and forensic purposes. In one embodiment, the invention provides a method of detecting an analyte in a fluid sample, the method comprising: passing a fluid sample containing a labeled analyte across at least one assay surface containing a capture agent for the analyte; detecting the labeled analyte; repeating the passing and detecting steps at least once; and creating a binding curve for the analyte based on the detecting of the labeled analyte. | 2012-05-24 |
20120129272 | LATERAL FLOW ASSAY SYSTEMS AND METHODS - In one aspect, a diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port for receiving a test strip. The reader obtains separable light intensity measurements from localized regions of an area of the detection zone exposed for optical inspection, wherein each of the localized regions is characterized by at least one surface dimension smaller than the first dimension. The data analyzer identifies ones of the light intensity measurements obtained from the at least one test region and computes at least one parameter from the identified ones of the light intensity measurements. In another aspect, the reader obtains a respective set of light intensity measurements from each of multiple corresponding regions of the exposed surface area of the detection zone, and the data analyzer computes at least one parameter from at least one of the sets of light intensity measurements. | 2012-05-24 |
20120129273 | PHOTOLITHOGRAPHICALLY DEFINED CONTACTS TO CARBON NANOSTRUCTURES - Methods for the fabrication of nanostructures, including nanostructures comprised of carbon nanotubes, and the nanostructures, devices, and assemblies prepared by these methods, are described. | 2012-05-24 |
20120129274 | PHOTODIODE SELF-TEST - A photodetector array includes a plurality of photodetector cells such as avalanche photodiodes and readout circuits. An array self-tester tests a dark count or other performance characteristic of the cells. The test is performed in connection with the manufacture of the array or following the installation of the array in a detection system. | 2012-05-24 |
20120129275 | DUAL-BULB LAMPHEAD CONTROL METHODOLOGY - The present invention generally relates to methods of controlling UV lamp output to increase irradiance uniformity. The methods generally include determining a baseline irradiance within a chamber, determining the relative irradiance on a substrate corresponding to a first lamp and a second lamp, and determining correction or compensation factors based on the relative irradiances and the baseline irradiance. The lamps are then adjusted via closed loop control using the correction or compensation factors to individually adjust the lamps to the desired output. The lamps may optionally be adjusted to equal irradiances prior to adjusting the lamps to the desired output. The closed loop control ensures process uniformity from substrate to substrate. The irradiance measurement and the correction or compensation factors allow for adjustment of lamp set points due to chamber component degradation, chamber component replacement, or chamber cleaning. | 2012-05-24 |
20120129276 | 4D Process and Structure - A 4D device comprises a 2D multi-core logic and a 3D memory stack connected through the memory stack sidewall using a fine pitch T&J connection. 3D memory in the stack is thinned from the original wafer thickness to no remaining Si. A tongue and groove device at the memory wafer top and bottom surfaces allows an accurate stack alignment. The memory stack also has micro-channels on the backside to allow fluid cooling, and is further diced at the fixed clock-cycle distance, and flipped on its side and re-assembled on to a template into a pseudo-wafer format. The top side wall of the assembly is polished and built with BEOL to fan-out and use the T&J fine pitch connection to join to the 2D logic wafer. The other side of the memory stack is polished, fanned-out, and bumped with C4 solder. The invention also comprises a process for manufacturing the device. | 2012-05-24 |
20120129277 | METHODS AND APPARATUSES FOR DETERMINING THICKNESS OF A CONDUCTIVE LAYER - Methods and apparatuses for calibrating eddy current sensors. A calibration curve is formed relating thickness of a conductive layer in a magnetic field to a value measured by the eddy current sensors or a value derived from such measurement, such as argument of impedance. The calibration curve may be an analytic function having infinite number terms, such as trigonometric, hyperbolic, and logarithmic, or a continuous plurality of functions, such as lines. High accuracy allows the omission of optical sensors, and use of eddy current sensors for endpoint detection, transition call detection, and closed loop control in which a process parameter is changed based on the measured magnetic flux density change in one or more processing zones. | 2012-05-24 |
20120129278 | DRY ETCHING METHOD - A dry etching method includes a first step and a second step. The first step includes generating a first plasma from a gas mixture, which includes an oxidation gas and a fluorine containing gas, and performing anisotropic etching with the first plasma on a silicon layer to form a recess in the silicon layer. The second step includes alternately repeating an organic film forming process whereby an organic film is deposited on the inner surface of the recess with a second plasma, and an etching process whereby the recess covered with the organic film is anisotropically etched with the first plasma. When an etching stopper layer is exposed from a part of the bottom surface of the recess formed in the first step, the first step is switched to the second step. | 2012-05-24 |
20120129279 | IMPRINTING METHOD, IMPRINTING APPARATUS AND MEDIUM - According to one embodiment, there is provided an imprinting method for applying a first hardening resin material on a substrate to be processed and transferring a pattern of a semiconductor integrated circuit formed on a template onto the substrate to be processed on which the first hardening resin material is applied, wherein a second hardening resin material with higher separability than the first hardening resin material is applied on at least part of the outer periphery of an area in which the pattern is formed by one transferring. | 2012-05-24 |
20120129280 | Method of Manufacturing Light Emitting Device - A method of manufacturing a light emitting device is provided which requires low cost, is easy, and has high throughput. The method of manufacturing a light emitting device is characterized in that: a solution containing a light emitting material is ejected to an anode or cathode under reduced pressure; a solvent in the solution is volatilized until the solution reaches the anode or cathode; and the remaining light emitting material is deposited on the anode or cathode to form a light emitting layer. A burning step for reduction in film thickness is not required after the solution application. Therefore, the manufacturing method, which requires low cost and is easy but which has high throughput, can be provided. | 2012-05-24 |
20120129281 | RESIN DISPENSING APPARATUS FOR LIGHT EMITTING DEVICE PACKAGE AND METHOD OF MANUFACTURING LIGHT EMITTING DEVICE PACKAGE USING THE SAME - There is provided a resin dispensing apparatus for a light emitting device package and a method of manufacturing a light emitting device package using the same. The resin dispensing apparatus includes a resin dispensing part including a resin storage portion filled with a resin therein and a resin discharge portion combined with the resin storage portion and discharging the resin therefrom; a supporting part having a light emitting device package disposed on an upper surface thereof and electrically connected to the light emitting device package; a voltage applying part having both terminals respectively connected to the resin dispensing part and the supporting part to apply a voltage thereto; and a sensing part electrically connected to the resin dispensing part and the supporting part individually and sensing a contact between the resin dispensing part and the light emitting device package with an electrical signal. | 2012-05-24 |
20120129282 | WAFER LEVEL CONFORMAL COATING FOR LED DEVICES - Provided is a method of fabricating a light-emitting diode (LED) device. The method includes providing a wafer. The wafer has light-emitting diode (LED) devices formed thereon. The method includes immersing the wafer into a polymer solution that has a surface tension lower than that of acetic acid. The polymer solution contains a liquid polymer and phosphor particles. The method includes lifting the wafer out of the polymer solution at a substantially constant speed. The method includes drying the wafer. The above processes form a conformal coating layer at least partially around the LED devices. The coating layer includes the phosphor particles. The coating layer also has a substantially uniform thickness. | 2012-05-24 |
20120129283 | LIGHT EMITTING DEVICE AND METHOD FOR ENHANCING LIGHT EXTRACTION THEREOF - A method for enhancing light extraction of a light emitting device is disclosed. The method includes the steps of: providing a site layer on the light emitting device; placing a protection layer on the site layer; forming an array of pores through the protection layer and the site layer; and growing on the site layer an oxide layer, having a plurality of rods, each of which is formed in one of the pores. The shapes of the rods can be well controlled by adjusting reactive temperature, time and N | 2012-05-24 |
20120129284 | METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY PIXEL ARRAY - This invention discloses a method for manufacturing liquid crystal display pixel array, which is capable of promoting an aperture ratio. The method of this invention includes forming a gate metal layer on a glass substrate; forming a gate insulation layer; forming a semiconductor layer; forming a second metal layer on the semiconductor layer; forming a switch region photoresist layer and a data line region photoresist layer on the second metal layer; etching the second metal layer; etching the semiconductor layer; etching the switch region photoresist layer and the data line region photoresist layer; and etching edge portions of the semiconductor in the switch region and the data line region by using fluoride-bearing gas. To etch off more edge portions of the semiconductor in the data line region, according to this invention, the thickness of the data line region photoresist layer is made thinner when forming the photoresist layer. | 2012-05-24 |
20120129285 | METHODS FOR MANUFACTURING DISPLAY PANEL AND DISPLAY APPARATUS - The present invention provides methods for manufacturing a display panel and a display apparatus. The method comprises the following steps: sputtering alignment layers on substrates; forming a liquid crystal layer between the alignment layers to form a liquid crystal cell; applying a voltage to the liquid crystal cell; irradiating an ultraviolet light to the liquid crystal cell; and arranging the display panel on a backlight module. The invention can improve the quality of alignment films of the liquid crystal display panel. | 2012-05-24 |
20120129286 | PIXEL STRUCTURE OF DISPLAY AND METHOD FOR MANUFACTURING THE SAME - A pixel structure of a display including a first substrate, a second substrate, and a liquid crystal (LC) layer disposed therebetween. The pixel structure comprises a plurality of first, second, and third sub-pixels; a plurality of alignment controlling patterns, respectively formed in the first, second and third sub-pixels for controlling alignment direction of LC molecules of the LC layer; a plurality of opaque regions, respectively formed in the first, second, and third sub-pixels, and substantially aligned with the portion of the alignment controlling patterns, so that the alignment controlling patterns are shielded by the substantially corresponded opaque regions having different areas in at least two of the colored sub-pixels. | 2012-05-24 |
20120129287 | DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME - According to one aspect of the present invention, a laminated structure of conductive transparent oxide layers containing silicon or silicon oxide is applied as an electrode on the side of injecting a hole (a hole injection electrode; an anode) instead of the conventional conductive transparent oxide layer such as ITO. In addition, according to another aspect of the invention, a laminated structure of conductive transparent oxide layers containing silicon or silicon oxide, each of which content is different, is applied as a hole injection electrode. Preferably, silicon or a silicon oxide, concentration of the conductive layer on the side where it is connected to a TFT ranges from 1 atomic % to 6 atomic % and a silicon or silicon oxide concentration on the side of a layer containing an organic compound ranges from 7 atomic % to 15 atomic %. | 2012-05-24 |
20120129288 | DISPLAY DEVICE AND MANUFACTURING METHOD OF THE SAME - A display device including a thin film transistor with high electric characteristics and high reliability, and a method for manufacturing the display device with high mass-productivity. In a display device including an inverted-staggered channel-stop-type thin film transistor, the inverted-staggered channel-stop-type thin film transistor includes a microcrystalline semiconductor film including a channel formation region, and an impurity region containing an impurity element of one conductivity type is selectively provided in a region which is not overlapped with source and drain electrodes, in the channel formation region of the microcrystalline semiconductor film. | 2012-05-24 |
20120129289 | NITRIDE SEMICONDUCTOR LIGHT EMITTING DEVICE AND METHOD OF MANUFACTURING THE SAME - A nitride semiconductor light emitting device, and a method of manufacturing the same are disclosed. The nitride semiconductor light emitting device includes a substrate, an n-type nitride semiconductor layer disposed on the substrate and including a plurality of V-shaped pits in a top surface thereof, an active layer disposed on the n-type nitride semiconductor layer and including depressions conforming to the shape of the plurality of V-shaped pits, and a p-type nitride semiconductor layer disposed on the active layer and including a plurality of protrusions on a top surface thereof. Since the plurality of V-shaped pits are formed in the top surface of the n-type nitride semiconductor layer, the protrusions can be formed on the p-type nitride semiconductor layer as an in-situ process. Accordingly, the resistance to ESD, and light extraction efficiency are enhanced. | 2012-05-24 |
20120129290 | METHOD FOR FORMING SEMICONDUCTOR NANO-MICRO RODS AND APPLICATIONS THEREOF - An embodiment of this invention utilizes ZnO rods as the etching mask to etch a GaN layer arranged below, so that GaN rods are formed. The GaN rods have similar patterns as the ZnO rods. The pattern, size, position, and height of the GaN rods are respectively controlled by the pattern, size, position, and height of the ZnO rods. | 2012-05-24 |
20120129291 | METHOD FOR PRODUCING A MICROMECHANICAL COMPONENT - A method for producing a micromechanical component is described. The method includes providing a substrate having a layer system including an insulating material situated on the substrate, a conductive layer section and a protective layer structure connected to the conductive layer section, which borders a section of the insulating material. The method furthermore includes carrying out an isotropic etching process for removing a part of the insulating material, the conductive layer section and the protective layer structure preventing the removal of the bordered section of the insulating material; and a structural element being developed, which includes the conductive layer section, the protective layer structure and the bordered section of the insulating material. | 2012-05-24 |
20120129292 | LAMINATING ASSEMBLY - A carrier assembly for temporary accommodation of one or more solar cell laminates while the solar laminates are conveyed through a lamination plant. The solar cell laminate comprises a solar cell layer of silicon material, an upper and a lower encapsulating layer of EVA material covering the top and bottom of the solar cell layer, an upper and lower protective layer covering the upper and lower encapsulating layer, respectively. The encapsulating layer has a specific melting temperature and a specific curing temperature; the melting temperature is lower than the curing temperature. The carrier assembly comprises a carrier housing of heat conductive material which defines an inner volume, the carrier housing has an upper plate adapted to receive the solar cell laminate and an opposite lower plate which defines a first plurality of apertures the inner volume includes one or more connecting elements which interconnect the first and second plates The carrier further comprises an air supply system to provide a continuous outward air flow through the first plurality of apertures when the lower plate is received on a conveying surface of the lamination plant the airflow yields an elevated and substantially balanced air pressure on the lower plate to provide lift or buoyancy to the carrier housing and allows a substantially friction-free movement of the carrier housing in relation to the conveying surface of the lamination plant. The carrier further comprises a thermal transfer system which provides thermal energy to the upper plate to allow the encapsulating layer to melt and subsequently cure and preferably is adapted to provide a temperature on the upper plate of 80-130° C. | 2012-05-24 |
20120129293 | METHODS OF MAKING AN UNSUPPORTED ARTICLE OF A SEMICONDUCTING MATERIAL USING THERMALLY ACTIVE MOLDS - The invention relates to methods of making unsupported articles of semiconducting material using thermally active molds having an external surface temperature, T | 2012-05-24 |
20120129294 | FAST PHOTOCONDUCTOR - A photoconductor comprising a layer stack with a semiconductor layer photoconductive for a predetermined wavelength range between two semiconductor boundary layers with a larger band gap than the photoconductive semiconductor layer on a substrate, wherein the semiconductor boundary layers comprise deep impurities for trapping and recombining free charge carriers from the photoconductive semiconductor layer, and two electrodes connected to the photoconductive semiconductor layer, for lateral current flow between the electrodes through the photoconductive semiconductor layer. | 2012-05-24 |
20120129295 | METHOD OF MANUFACTURING PHOTOELECTRIC CONVERSION DEVICE - Disclosed herein is a photoelectric conversion device having a semiconductor substrate including a front side and back side, a protective layer formed on the front side of the semiconductor substrate, a first non-single crystalline semiconductor layer formed on the back side of the semiconductor substrate, a first conductive layer including a first impurity formed on a first portion of a back side of the first non-single crystalline semiconductor layer, and a second conductive layer including the first impurity and a second impurity formed on a second portion of the back side of the first non-single crystalline semiconductor layer. | 2012-05-24 |
20120129296 | METHOD FOR FORMING AN ORGANIC MATERIAL LAYER ON A SUBSTRATE - A method for forming an organic material layer on a substrate in an in-line deposition system is disclosed. In one aspect, the organic material is deposited with a predetermined non-constant deposition rate profile, which includes a first predetermined deposition rate range provided to deposit at least a first monolayer of the organic material layer with a first predetermined average deposition rate and a second predetermined deposition rate range provided to deposit at least a second monolayer of the organic material layer with a second predetermined average deposition rate. The injection of organic material through the openings of the injector is controlled for realizing the predetermined deposition rate profile. | 2012-05-24 |
20120129297 | METHOD OF MANUFACTURING WAFER LEVEL PACKAGE - A method of manufacturing a wafer level package including: separating chips by dicing a wafer; forming a removable resin layer in a space between the separated chips and at upper parts thereof; separating the chips by dicing the removable resin layer; mounting the chips separated in a state of being surrounded by the removable resin layer, on a carrier plate; forming a molding material on the carrier plate to cover the removable resin layer; separating the carrier plate from the chips; forming a dielectric layer having redistribution lines connected to the chips, on the chips exposed by separating the carrier plate; and forming a solder resist layer on the dielectric layer to expose portions of the redistribution lines. | 2012-05-24 |
20120129298 | METHOD OF MAKING STACKABLE SEMICONDUCTOR ASSEMBLY WITH BUMP/FLANGE HEAT SPREADER AND DUAL BUILD-UP CIRCUITRY - A method of making a stackable semiconductor assembly that includes a semiconductor device, a heat spreader, an adhesive, a plated through-hole, first build-up circuitry and second build-up circuitry is disclosed. The heat spreader includes a bump and a flange. The bump defines a cavity. The semiconductor device is mounted on the bump at the cavity, electrically connected to the first build-up circuitry and thermally connected to the bump. The bump extends into an opening in the adhesive and the flange extends laterally from the bump at the cavity entrance. The first build-up circuitry and the second build-up circuitry extend beyond the semiconductor device in opposite vertical directions. The plated through-hole extends through the adhesive and provides signal routing between the first build-up circuitry and the second build-up circuitry. The heat spreader provides heat dissipation for the semiconductor device. | 2012-05-24 |
20120129299 | METHOD OF MAKING THERMALLY ENHANCED SEMICONDUCTOR ASSEMBLY WITH BUMP/BASE/FLANGE HEAT SPREADER AND BUILD-UP CIRCUITRY - A method of making a semiconductor assembly that includes a semiconductor device, a heat spreader, an adhesive and a build-up circuitry is disclosed. The heat spreader includes a bump, a base and a flange. The bump defines a cavity. The semiconductor device is mounted on the bump at the cavity, electrically connected to the build-up circuitry and thermally connected to the bump. The bump extends from the base into an opening in the adhesive, the base extends vertically from the bump opposite the cavity and the flange extends laterally from the bump at the cavity entrance. The build-up circuitry includes a dielectric layer and conductive traces on the semiconductor device and the flange. The conductive traces provide signal routing for the semiconductor device. | 2012-05-24 |
20120129300 | METHOD OF MAKING STACKABLE SEMICONDUCTOR ASSEMBLY WITH BUMP/BASE/FLANGE HEAT SPREADER AND BUILD-UP CIRCUITRY - A method of making a stackable semiconductor assembly that includes a semiconductor device, a heat spreader, an adhesive, a terminal, a plated through-hole and build-up circuitry is disclosed. The heat spreader includes a bump, a base and a flange. The bump defines a cavity. The semiconductor device is mounted on the bump at the cavity, electrically connected to the build-up circuitry and thermally connected to the bump. The bump extends from the base into an opening in the adhesive, the base extends vertically from the bump opposite the cavity and the flange extends laterally from the bump at the cavity entrance. The build-up circuitry provides signal routing for the semiconductor device. The plated through-hole provides signal routing between the build-up circuitry and the terminal. The heat spreader provides heat dissipation for the semiconductor device. | 2012-05-24 |
20120129301 | SYSTEM COMPRISING A SEMICONDUCTOR DEVICE AND STRUCTURE - A method of manufacturing a semiconductor device, the method including, providing a first monocrystalline layer including semiconductor regions, overlaying the first monocrystalline layer with an isolation layer, transferring a second monocrystalline layer comprising semiconductor regions to overlay the isolation layer, wherein the first monocrystalline layer and the second monocrystalline layer are formed from substantially different crystal materials; and subsequently etching the second monocrystalline layer as part of forming at least one transistor in the second monocrystalline layer. | 2012-05-24 |
20120129302 | FABRICATING PHOTONICS DEVICES FULLY INTEGRATED INTO A CMOS MANUFACTURING PROCESS - Disclosed are process enhancements to fully integrate the processing of a photonics device into a CMOS manufacturing process flow. A CMOS wafer may be divided into different portions. One of the portions is for the CMOS devices and one or more other portions are for the photonics devices. The photonics devices include a ridged waveguide and a germanium photodetector. The germanium photodetector may utilize a seeded crystallization from melt process so there is more flexibility in the processing of the germanium photodetector. | 2012-05-24 |
20120129303 | METHODS FOR MANUFACTURING PASSIVATION LAYER AND THIN FILM TRANSISTOR ARRAY SUBSTRATE - The present invention provides methods for manufacturing a passivation layer and a thin film transistor (TFT) array substrate. The method for manufacturing the passivation layer comprises the following steps: placing a substrate in a vacuum process chamber; providing an ammonia gas and a nitrogen gas into the vacuum process chamber; forming plasma and evaporating water vapor; and forming the passivation layer on the substrate. The method for manufacturing the passivation layer can be applicable to the method for manufacturing the TFT array substrate. The present invention can enhance the quality of the passivation layer. | 2012-05-24 |
20120129304 | FIN-TYPE FIELD EFFECT TRANSISTOR - Disclosed herein are improved fin-type field effect transistor (FinFET) structures and the associated methods of manufacturing the structures. In one embodiment FinFET drive current is optimized by configuring the FinFET asymmetrically to decrease fin resistance between the gate and the source region and to decrease capacitance between the gate and the drain region. In another embodiment device destruction at high voltages is prevented by ballasting the FinFET. Specifically, resistance is optimized in the fin between the gate and both the source and drain regions (e.g., by increasing fin length, by blocking source/drain implant from the fin, and by blocking silicide formation on the top surface of the fin) so that the FinFET is operable at a predetermined maximum voltage. | 2012-05-24 |
20120129305 | METHOD FOR MANUFACTURING A MOS-FIELD EFFECT TRANSISTOR - A method for manufacturing a Metal-Oxide-Semiconductor Field-Effect-Transistor (MOSFET) has the step of implanting a base region of said MOSFET within an epitaxial layer of a semiconductor chip comprising an insulated gate structure used as a masking element, wherein the implant beam is angled with respect to a vertical axis of the semiconductor chip such that the base region extends sufficiently under the gate to form a Power-MOSFET. | 2012-05-24 |
20120129306 | CONFIGURATION AND METHOD TO FORM MOSFET DEVICES WITH LOW RESISTANCE SILICIDE GATE AND MESA CONTACT REGIONS - A novel integration scheme for forming power MOSFET, particularly forming salicided layers for both gate contact regions and mesa contact regions, as well as using multiple energy contact implants through the salicided layer to form conductive body contacts which short to the source region by the salicided layers. | 2012-05-24 |
20120129307 | SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD OF THE SAME - The present invention provides a technique capable of attaining an improvement in current detection accuracy in a trench gate type power MISFET equipped with a current detection circuit. Inactive cells are disposed so as to surround the periphery of a sense cell. That is, the inactive cell is provided between the sense cell and an active cell. All of the sense cell, active cell and inactive cells are respectively formed of a trench gate type power MISFET equipped with a dummy gate electrode. At this time, the depth of each trench extends through a channel forming region and is formed up to the deep inside (the neighborhood of a boundary with a semiconductor substrate) of an n-type epitaxial layer. Further, a p-type semiconductor region is provided at a lower portion of each trench. The p-type semiconductor region is formed so as to contact the semiconductor substrate. | 2012-05-24 |
20120129308 | Performance Enhancement in PMOS and NMOS Transistors on the Basis of Silicon/Carbon Material - A silicon/germanium material and a silicon/carbon material may be provided in transistors of different conductivity type on the basis of an appropriate manufacturing regime without unduly contributing to overall process complexity. Furthermore, appropriate implantation species may be provided through exposed surface areas of the cavities prior to forming the corresponding strained semiconductor alloy, thereby additionally contributing to enhanced overall transistor performance. In other embodiments a silicon/carbon material may be formed in a P-channel transistor and an N-channel transistor, while the corresponding tensile strain component may be overcompensated for by means of a stress memorization technique in the P-channel transistor. Thus, the advantageous effects of the carbon species, such as enhancing overall dopant profile of P-channel transistors, may be combined with an efficient strain component while enhanced overall process uniformity may also be accomplished. | 2012-05-24 |
20120129309 | METHOD FOR FABRICATING HIGH-GAIN MOSFETS WITH ASYMMETRIC SOURCE/DRAIN DOPING FOR ANALOG AND RF APPLICATIONS - A method of fabrication of an analog, asymmetric Metal-Oxide-Semiconductor-Field-Effect-Transistor (MOSFET) is provided. The method may comprise forming a first gate oriented in a first direction over an active region of a semiconductor substrate, forming a second gate extending perpendicular to the first gate over a second active region, using a dual-directional implant process to form a reduced-HALO doped area on a drain side of the first gate and also for a HALO doped area for the second gate, while the source side of the first gate is covered by a resist. Additionally, the method may comprise forming a HALO doped area on the source side of the first gate using a quad-directional implant process using the mask also used for HALO implants of other digital-logic devices on the substrate, while the drain side of the gate is blocked by a resist. | 2012-05-24 |
20120129310 | METHODS OF FABRICATING A SEMICONDUCTOR DEVICE HAVING A HIGH-K GATE DIELECTRIC LAYER AND SEMICONDUCTOR DEVICES FABRICATED THEREBY - A method of fabricating a semiconductor device includes forming a lower interfacial layer on a semiconductor layer, the lower interfacial layer being a nitride layer, forming an intermediate interfacial layer on the lower interfacial layer, the intermediate interfacial layer being an oxide layer, and forming a high-k dielectric layer on the intermediate interfacial layer. The high-k dielectric layer has a dielectric constant that is higher than dielectric constants of the lower interfacial layer and the intermediate interfacial layer. | 2012-05-24 |
20120129311 | METHOD OF MANUFACTURING A TRANSISTOR DEVICE HAVING ASYMMETRIC EMBEDDED STRAIN ELEMENTS - Semiconductor transistor devices and related fabrication methods are provided. An exemplary transistor device includes a layer of semiconductor material having a channel region defined therein and a gate structure overlying the channel region. Recesses are formed in the layer of semiconductor material adjacent to the channel region, such that the recesses extend asymmetrically toward the channel region. The transistor device also includes stress-inducing semiconductor material formed in the recesses. The asymmetric profile of the stress-inducing semiconductor material enhances carrier mobility in a manner that does not exacerbate the short channel effect. | 2012-05-24 |
20120129312 | METHOD OF FORMING E-FUSE IN REPLACEMENT METAL GATE MANUFACTURING PROCESS - Embodiment of the present invention provides a method of forming electronic fuse or commonly known as e-fuse. The method includes forming a polysilicon structure and a field-effect-transistor (FET) structure together on top of a common semiconductor substrate, the FET structure having a sacrificial gate electrode; implanting at least one dopant into the polysilicon structure to create a doped polysilicon layer in at least a top portion of the polysilicon structure; subjecting the polysilicon structure and the FET structure to a reactive-ion-etching (RIE) process, the RIE process selectively removing the sacrificial gate electrode of the FET structure while the doped polysilicon layer being substantially unaffected by the RIE process; and converting the polysilicon structure including the doped polysilicon layer into a silicide to form the electronic fuse. | 2012-05-24 |