| 17th week of 2013 patent applcation highlights part 51 |
| Patent application number | Title | Published |
|---|
| 20130102759 | Synthetic Oligosaccharides for Moraxella Vaccine - The present invention provides synthetic | 2013-04-25 |
| 20130102760 | Immunoglobulin Preparations Having Increased Stability - The present invention relates to a protein preparation having increased stability, comprising a stabiliser selected from the group consisting of non-polar and basic amino acids and having a pH of 4.0 to 5.2. The invention further relates to a pharmaceutical composition and a method of stabilising protein preparations. | 2013-04-25 |
| 20130102761 | SOLID PHASE FOR MIXED-MODE CHROMATOGRAPHIC PURIFICATION OF PROTEINS - Proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of no more than three atoms between the hydrophobic group and the support matrix. | 2013-04-25 |
| 20130102762 | ANTI-PSGL-1 ANTIBODIES - Immunoglobulin chains or antibodies having light or heavy chain complementarity determining regions of antibodies that bind to P-Selectin Glycoprotein Ligand-1. Also disclosed are methods of inducing death of an activated T-cell and of modulating a T cell-mediated immune response in a subject. | 2013-04-25 |
| 20130102763 | Method of thermostabilization of a protein and/or stabilization towards organic solvents - Thermostabilization of a protein where the protein contains access routes and wherein at least one amino acid in the bottleneck of the access route is mutated, includes identifying the amino acids of the bottleneck and the amino acids control exchange of the solvent between a buried protein core and surrounding environment and/or in the packing of the amino acids inside the access route. Modification of the amino acids are determined so that the packing of the amino acids inside the tunnel is improved and the access route prevents access of undesired solvent molecules to the protein core, while allowing passage of the compounds necessary at the protein core to enable the protein to perform its biological function. | 2013-04-25 |
| 20130102764 | PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF - Processes for the synthesis of the Factor Xa anticoagulent Fondaparinux, and related compounds are described. Also described are protected pentasaccharide intermediates as well as efficient and scalable processes for the industrial scale production of Fondaparinux sodium by conversion of the protected pentasaccharide intermediates via a sequence of deprotection and sulfonation reactions. | 2013-04-25 |
| 20130102765 | NOVEL GLYPHOSATE-N-ACETYLTRANSFERASE (GAT) GENES - Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate. | 2013-04-25 |
| 20130102766 | METHOD AND COMPOSITIONS FOR MONITORING DNA BINDING MOLECULES IN LIVING CELLS - The present invention provides a method of screening for a compound that binds to a selected nucleic acid comprising contacting compound fluorescently labeled by a fluorescent protein with a cell having a plurality of copies of the nucleic acid in an array such that the nucleic acid can be directly detected when bound by fluorescently labeled compound; and directly detecting the location of fluorescence within the cell, fluorescence aggregated at the site of the nucleic acid array indicating a compound that binds to the selected nucleic acid. In particular compounds such a transcription factors can be screened. Reagents for such method are provided including a mammalian cell having a plurality of steroid receptor response elements in an array such that the response element can be directly detected when bound by fluorescently labeled steroid receptor and a chimeric protein comprising a fluorescent protein fused to a steroid receptor. | 2013-04-25 |
| 20130102767 | NUCLEIC ACID SEQUENCES ENCODING STRICTOSIDINE SYNTHASE PROTEINS - Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants. | 2013-04-25 |
| 20130102768 | EFFICIENT METHOD FOR NUCLEAR REPROGRAMMING - A method of preparing induced pluripotent stem cells, comprising a nuclear reprogramming step with a nuclear reprogramming factor in the presence of miRNA, wherein said miRNA has a property of providing a higher nuclear reprogramming efficiency in the presence of said miRNA than in the absence thereof. | 2013-04-25 |
| 20130102769 | INTERFERING RNA MOLECULES - The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double-stranded structure comprises a first strand and a second strand, whereby the first strand comprises a first stretch of contiguous nucleotides and whereby said first stretch is at least partially complementary to a target nucleic acid, and the second strand comprises a second stretch of contiguous nucleotides whereby said second stretch is at least partially identical to a target nucleic acid, and whereby the double stranded structure is blunt ended. | 2013-04-25 |
| 20130102770 | METAL ENHANCED FLUORESCENCE-BASED SENSING METHODS - The present invention relates to metallic-surface detection systems for determining target substances including free bilirubin in neonatal serum in the presence of a predominantly high background of bilirubin bound Human Serum Albumin (HSA) or sensing and isolating target nucleotide sequences wherein a fluorescence signal is enhanced by close proximity of the target substances near metallic surfaces. | 2013-04-25 |
| 20130102771 | NEURITE OUTGROWTH AGENT - An object of the present invention is to provide a non-peptidic nerve axon and/or neurite outgrowth agent for allowing a nerve axon and a neurite to elongate. 3-(Aminocarbonyl)-1-[5-O-[[1-(6-amino-9H-purin-9-yl)-1-deoxy-β-D-ribofuranos-5-O-yl]phosphonyloxy(oxylato)phosphinyl]-β-L-ribofuranosyl]pyridinium that is an analogue of nicotinamide adenine dinucleotide (NAD) comprising β-L-ribose as the sugar component is used as a nerve axon and/or neurite outgrowth agent or composition, a cancer cell growth suppressing and/or apoptosis inducing agent, or a cancer cell growth suppressing and/or apoptosis inducing composition. | 2013-04-25 |
| 20130102772 | SYSTEMS, METHODS AND DEVICES FOR PRODUCING, MANUFACTURING AND CONTROL OF RADIOPHARMACEUTICALS-FULL - Systems, methods, and devices for generating radionuclides for use in production of radiopharmaceuticals; synthesizing the radionuclides generated and removing any unwanted products; measuring the quantity and activity level of the synthesized radionuclides; distributively delivering the radionuclides in appropriate quantities to modular cassette synthesis units in a modular cassette subsystem for contemporaneous/parallel production of radiopharmaceutical output and that allow reuse and/or quick, safe, and disposable replacement of portions of the subsystem; delivering non-radionuclide components to the modular cassette synthesis units as part of production of radiopharmaceutical output; measuring the quantity and activity level of each stream of radiopharmaceutical output; purifying the radiopharmaceutical output; dispensing individual doses in sterile vial(s); automatically producing labeling and dose related information; performing automated quality control on extracted samples of produced radiopharmaceutical output; and providing software and hardware controls for overall and sub-portion operation for optional remote data collection, communication, and/or control. | 2013-04-25 |
| 20130102773 | METHOD OF PREPARING SUCRALOSE-6-ESTER BY CATALYSIS AND CHLORINATION OF PHASE TRANSFER CATALYST - A method of preparing sucralose-6-ester by catalysis and chlorination of phase transfer catalyst comprises the following steps: add phase transfer catalyst into a prepared Vilsmeier reagent and then drip in DMF solution of sucrose-6-ester at 5-10° C. to obtain a feed solution and after that maintain its temperature of the feed solution for 1-1.5 hours; next, increase temperature of the feed solution to 45-55° C. and maintain the temperature for 1-1.5 hours; next, increase the temperature to 75-85° C. and maintain the temperature for 1-1.5 hours; next, increase the temperature to 108-109° C., maintain the temperature for 2.5-3 hours and then remove a chlorine-containing solvent from the feed solution by concentration in reduced pressure for evaporation. After that, cool down the feed solution to room temperature and then pump in ammonia into the feed solution for neutralization. | 2013-04-25 |
| 20130102774 | THIONATION PROCESS AND A THIONATING AGENT - A process for transforming a group >C═O (I) in a compound into a group >C═S (II) or into a tautomeric form of group (II) in a reaction giving a thionated reaction product, by use of crystalline P | 2013-04-25 |
| 20130102775 | PHOTOCHROMIC MATERIAL - The present invention is a photochromic material formed of a biimidazole compound represented by general formula (1-1): | 2013-04-25 |
| 20130102776 | ANTICANCER AGENT - An anticancer agent comprising a compound represented by the formula (I) [R | 2013-04-25 |
| 20130102777 | PREPARATION OF 13-CYCLOHEXYL-3-METHOXY-6-[METHYL-(2--ETHYL)-CARBAMOYL]-7H-INDOLO-[2,1-a]- -[2]-BENZAZEPINE-10-CARBOXYLIC ACID - The present invention relates to an improved method for the preparation of 13-cyclohexyl-3-methoxy-6-[methyl-(2-{2-[methyl-(sulphamoyl)-amino]-ethoxy}-ethyl)-carbamoyl]-7H-indolo-[2,1-a]-[2]-benzazepine-10-carboxylic acid. The present invention also relates to a new compound, namely tert-butyl (methyl-{2-[2-(methylamino)-ethoxy]-ethyl}-sulphamoyl)-carbamate, used in this improved method. | 2013-04-25 |
| 20130102778 | PROCESS FOR THE PREPARATION OF ISOXAZOLYL- METHOXY NICOTINIC ACIDS - The present invention relates to a process for the preparation of a compound of formula (I) | 2013-04-25 |
| 20130102779 | Substituted Tetracycline Compounds - The present invention pertains to tetracycline compounds of formula (VIIa): | 2013-04-25 |
| 20130102780 | TRANSITION METAL-CATALYZED PROCESSES FOR THE PREPARATION OF N-ALLYL COMPOUNDS AND USE THEREOF - The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine. | 2013-04-25 |
| 20130102781 | METHODS OF MAKING COCRYSTALS - Disclosed are processes for preparing cocrystals, including processes for scaling up of cocrystal formation, as well as scalable processes for preparing cocrystals. Also disclosed are processes for scaled-up preparation of pterostilbene, progesterone, p-coumaric, and minoxidil cocrystals. Minoxidil cocrystals, such as minoxidil:benzoic acid 1:1 monohydrate cocrystals are also disclosed herein. | 2013-04-25 |
| 20130102782 | PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES - The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK). | 2013-04-25 |
| 20130102783 | SUBSTITUTED DIKETOPIPERAZINES AND THEIR USE AS OXYTOCIN ANTAGONISTS - Compounds of formula (1) | 2013-04-25 |
| 20130102784 | PROCESS FOR N-DEALKYLATION OF TERTIARY AMINES - The present disclosure provides improved methods for N-dealkylation of tertiary amines, including methods for N-demethylation of alkaloids and opioids, in which the dealkylation reaction is carried out in a solvent comprising a tertiary alcohol. The present disclosure also provides improved processes for preparing semi-synthetic opioids that incorporate the disclosed methods for N-dealkylation of tertiary amines. | 2013-04-25 |
| 20130102785 | METHOD OF MAKING COUPLED HETEROARYL COMPOUNDS VIA REARRANGEMENT OF HALOGENATED HETEROAROMATICS FOLLOWED BY OXIDATIVE COUPLING - The inventions disclosed and described herein relate to new and efficient generic methods for making a wide variety of compounds having Formulas (I) and (II) as shown below (Formulas (I) and (II)) wherein HAr is an optionally substituted five or six membered heteroaryl ring, and Hal is a halogen, and Y is a bridging radical, such as S, Se, NR | 2013-04-25 |
| 20130102786 | PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED 1-ALKYLTETRAZOLYL OXIME DERIVATIVES - The present invention relates to a process for the preparation of 5-substituted 1-alkyltetrazolyl oxime derivatives. | 2013-04-25 |
| 20130102787 | NOVEL INDAZOLE DERIVATIVE OR SALT THEREOF AND PRODUCTION INTERMEDIATE THEREOF, AND ANTIOXIDANT USING SAME, AND USE OF INDAZOLE DERIVATIVE OR SALT THEREOF - A compound represented by formula (1) or salt thereof and a production intermediate thereof are created. The compound exhibited an excellent antioxidation action in a microsome lipid peroxidation measuring system using a rat liver microsome. Therefore, the compound or salt thereof is useful as an antioxidant. The present invention also provides use of a compound represented by the formula (1) or a pharmaceutically acceptable salt thereof for production of an antioxidant. | 2013-04-25 |
| 20130102788 | Method for Synthesizing 1,3,5-Tri-(N-Phenylbenzimidazolyl) Benzene - The present invention relates to efficient synthetic method of 1,3,5-tris (N-Phenylbenzimidazole) Benzene and pertains to the field of synthesis of organic light-emitting materials. The method and process of the patent are as following: 1,3,5-tris (N-Phenyl-N Phenylammonium) Benzamide is treated by shrinking agent but no high temperature required, and then high purity product can be reached after raw material dissolved. The reaction only takes a few minutes and through recrystallization the purity can be over 99%, and then the material with stable crystal phase reached after sublimation step. The method introduced by the present patent is easy to operate, and with high in yield and purity, which adapt industrial production and has important significance for the industrialization. | 2013-04-25 |
| 20130102789 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS - Hafnium complexes of heterocyclic organic ligands having improved solubility in aliphatic hydrocarbon solvents and their use as components of olefin polymerization catalysts as well as novel syntheses of component parts thereof are disclosed. | 2013-04-25 |
| 20130102790 | FUNGICIDE N-CYCLOALKYL-N-BICYCLIMETHYLENE-CARBOXAMIDE DERIVATIVES - The present invention relates to N-cycloalkyl-N-bicyclicmethylene-carboxamide, thiocarboxamide or N-substituted carboximidamide derivatives of formula (I) wherein A represents a carbo-linked, 5-membered heterocyclyl group, T represents O or S, Z | 2013-04-25 |
| 20130102791 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS - Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed. | 2013-04-25 |
| 20130102792 | Organic Semiconductors - A semiconducting compound with the structure: | 2013-04-25 |
| 20130102793 | NEW FUNCTIONALIZED POLYHEDRAL OCTAVINYLSILSESQUIOXANES AND A METHOD TO OBTAIN THE FUNCTIONALIZED POLYHEDRAL OCTAVINYLSILSESQUIOXANES - A new functionalized polyhedral octavinylsilsesquioxanes having the general formula 1, in which R | 2013-04-25 |
| 20130102794 | Novel Process for the Preparation of Nitrogen Substituted Aminotetralins Derivatives - The present invention provides an alternative synthesis of N-substituted aminotetralines comprising resolution of N-substituted aminotetralins of formula (II), wherein R | 2013-04-25 |
| 20130102795 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS - Hafnium complexes of heterocyclic organic ligands having improved solubility in aliphatic hydrocarbon solvents and their use as components of olefin polymerization catalysts as well as novel syntheses of component parts thereof are disclosed. | 2013-04-25 |
| 20130102796 | AGENT FOR PROMOTING OSTEOBLAST DIFFERENTIATION, PHARMACEUTICAL COMPOSITION FOR PROMOTING BONE FORMATION, AND FOOD FOR SPECIAL DIETARY USE CONTAINING AURAPTENE ANALOG AS ACTIVE INGREDIENT - Agents or pharmaceutical compositions for promoting osteoblast differentiation include purified auraptene or coumarin analogs thereof represented by the following formula 1: | 2013-04-25 |
| 20130102797 | Co-Crystal Compound, Method for Preparing the Same and Oxidant of Gas Generator Propellant - A co-crystal compound containing ammonium nitrate and benzo-18-crown-6-ether. Ammonium nitrate and benzo-18-crown-6-ether are used to form the co-crystal compound with hydrogen bonding in a mole ratio of 1:1. A melting point of the co-crystal compound falls within a range of 124˜130° C., and the co-crystal compound can be prepared by an evaporation method or an anti-solvent method. The co-crystal compound comes with a non-hygroscopic property, a low burning rate (7 MPa, 0.58 mm/s) and a high pressure index (n>0.6), which can be used for replacing the oxidizer of a common gas generator propellant. | 2013-04-25 |
| 20130102798 | METHOD FOR PREPARING CHLOROHYDRINS AND METHOD FOR PREPARING EPICHLOROHYDRIN USING CHLOROHYDRINS PREPARED THEREBY - A method of preparing chlorohydrins and a method of preparing epichlorohydrin using chlorohydrins prepared by using the same method are provided. The method is to prepare chlorohydrins by reacting polyhydroxy aliphatic hydrocarbon with a chlorination agent in the presence of a catalyst, and the method includes at least one combination of a series of unit operations including the following steps in the following stated order: a first reaction step; a water removal step; and a second reaction step, wherein the water removing step is performed by distillation operation based on a boiling point difference between constituents of a reaction mixture. The method of preparing epichlorohydrin includes reacting chlorohydrins prepared by using the method of preparing chlorohydrins with an alkaline agent. | 2013-04-25 |
| 20130102799 | METHOD FOR PREPARING CHLOROHYDRINS COMPOSITION AND METHOD FOR PREPARING EPICHLOROHYDRIN USING CHLOROHYDRINS COMPOSITION PREPARED THEREBY - A method of preparing a chlorohydrin composition and a method of preparing epichlorohydrin by using a chlorohydrin composition prepared by using the method are provided. The method of preparing a chlorohydrin composition in which a polyhydroxy aliphatic hydrocarbon is reacted with a chlorination agent in the presence of a catalyst includes performing at least one combination of a series of unit operations comprising a first reaction step, a water removal step, and a second reaction step in this stated order, wherein the method further includes mixing a chlorohydrin concentrate obtained by purifying the reaction mixture discharged from the final reaction step from among the plurality of reaction steps and a water-rich layer discharged from the water-removal step. The method of preparing epichlorohydrin includes contacting the chlorohydrin composition prepared by using the method of preparing a chlorohydrin composition with an alkaline agent | 2013-04-25 |
| 20130102800 | METHOD FOR PREPARING CHLOROHYDRINS COMPOSITION AND METHOD FOR PREPARING EPICHLOROHYDRIN USING CHLOROHYDRINS COMPOSITION PREPARED THEREBY - Disclosed are a method for preparing chlorohydrins composition and a method for preparing epichlorohydrin using chlorohydrins prepared thereby. The disclosed method for preparing chlorohydrins composition reacts polyhydroxy aliphatic hydrocarbon with a chlorination agent in the presence of a catalyst, comprises at least one combination of a series of unit operations including a first reaction step, a water removal step, and a second reaction step in the respective order, and additionally comprises a step for reacting the chlorohydrins composition derived from a plurality of reaction mixtures discharged from the plurality of reaction steps with an alkaline chemical, and removing the catalyst included in the chlorohydrins composition in the form of an alkali metal salt. The disclosed method for preparing epichlorohydrin includes a step for contacting the chlorohydrins composition, which was prepared using the method for preparing chlorohydrins composition, with an alkaline chemical. | 2013-04-25 |
| 20130102801 | METHOD FOR PREPARING CHLOROHYDRINS COMPOSITION AND METHOD FOR PREPARING EPICHLOROHYDRIN USING CHLOROHYDRINS COMPOSITION PREPARED THEREBY - Provided are a method of preparing a chlorohydrin composition and a method of preparing epichlorohydrin by using a chlorohydrin composition prepared by using the method. The method of preparing chlorohydrins in which polyhydroxy aliphatic hydrocarbon is reacted with a chlorination agent in the presence of a catalyst includes performing at least one combination of a series of unit operations comprising a first reaction step, a water removal step, and a second reaction step in this stated order, wherein the method further includes mixing a chlorohydrin concentrate obtained by purifying the reaction mixture discharged from the final reaction step from among the reaction steps and a water-rich layer discharged from the water-removal step and diluting the mixture with water. The method of preparing epichlorohydrin includes contacting the chlorohydrin composition prepared by using the method of preparing a chlorohydrin composition with an alkaline agent. | 2013-04-25 |
| 20130102802 | Method of Lipid Extraction - A method of extracting lipids from wet algae, the method includes hydrolyzing a slurry comprising algae and water by adding an acidic hydrolyzing agent to yield an acidic slurry, hydrolyzing the acidic slurry by adding a basic hydrolyzing agent to yield a basic slurry, separating a liquid phase from biomass in the basic slurry, forming a precipitate within the liquid phase, and separating free fatty acids from the precipitated solid phase with the advantage of removed or reduced chlorophyll contamination of the algal lipids. | 2013-04-25 |
| 20130102803 | Mild Anionic Surfactants Suitable For Personal Care Compositions - A surfactant represented by the formula: | 2013-04-25 |
| 20130102804 | CHEMICAL SYNTHESIS COMPRISING HEAT TREATMENT BY INTERMITTENT DIELECTRIC HEATING, COMBINED WITH A RECYCLING SYSTEM - This invention relates to the design of a process by intermittent dielectric heating combined with a recycling system. | 2013-04-25 |
| 20130102805 | POROUS CERAMIC MATRIX - A porous ceramic matrix contains a plurality of ceramic particles adhered to each other, and a plurality of channels defined by surfaces of neighbouring ceramic particles, the channels each having an average diameter of 0.5-2.5 μm. Preferred ceramics also have a porosity of 25.0-40.0%, a Darcy's Permeability of 1.57-34.8×10 | 2013-04-25 |
| 20130102806 | METHOD FOR SYNTHESIZING RARE EARTH METAL EXTRACTANT - A rare earth metal extractant containing, as the extractant component, dialkyldiglycol amide acid which is excellent in breaking down light rare earth elements is reacted in diglycolic acid (X mol) and an esterification agent (Y mol) at a reaction temperature of 70° C. or more and for a reaction time of one hour or more such that the mol ratio of Y/X is 2.5 or more, and is subjected to vacuum concentration. Subsequently, a reaction intermediate product is obtained by removing unreacted products and reaction residue, and an aprotic polar solvent is added as the reaction solvent. Then, the reaction intermediate product is reacted with dialkyl amine (Z mol) such that the mol ratio of Z/X is 0.9 or more and the aprotic polar solvent is removed. As a consequence, a rare earth metal extractant is efficiently synthesized at a low cost and at a high yield without having to use expensive diglycolic acid anhydride and harmful dichloromethane. | 2013-04-25 |
| 20130102807 | PROCESS FOR PREPARING FORMAMIDES AND FORMIC ESTERS - A process for preparing carboxylic acid derivatives of the formula H—(C═O)—R, R is OR | 2013-04-25 |
| 20130102808 | METHOD FOR THE MANUFACTURE OF PHOSPHONOALKYL IMINODIACETIC ACID - An improved method for the manufacture of phosphonoalkyl iminodiacetic acid M | 2013-04-25 |
| 20130102809 | Methanol Carbonylation Process with Rhodium Catalyst, an Iodide Salt and a Metallic Co-Catalyst Selected from Transition Metals, Indium, Strontium, Barium, Zinc, Tin and Heteropoly Acids - A carbonylation process for making acetic acid uses a metallic co-catalyst composition effective as a rhodium stabilizer and rate promoter at molar ratios of metal/rhodium of from about 0.5 to 30. A preferred process includes: (a) reacting methanol with a carbon monoxide feedstock in a rhodium-based catalytic reaction mixture having: (i) a rhodium catalyst metal, (ii) methyl iodide maintained from about 1 to 20 weight percent, (iii) a lithium iodide co-catalyst, (iv) a metallic co-catalyst composition, (v) water maintained from 0.1 weight percent to less than 8 weight percent, (vi) methyl acetate maintained from about 0.5 to about 30 weight percent, and (vii) acetic acid; (b) flashing crude acetic acid from the reaction mixture; and (c) purifying the crude acetic acid. This process achieves stability and a STY greater than 10 mol/L/hr, with substantially less than a theoretically equivalent inorganic iodide content corresponding to the metallic co-catalyst and lithium iodide. | 2013-04-25 |
| 20130102810 | Methanol Carbonylation Process with Rhodium Catalyst and a Lanthanide Metal Co-Catalyst - A carbonylation process for making acetic acid using a metallic co-catalyst composition, effective as a rhodium stabilizer and/or rate promoter, at molar ratios of metal/rhodium of about 0.5 to 40. The process includes reacting methanol with carbon monoxide in the presence of a rhodium-based catalytic metal complex with about 1 to 20 weight percent methyl iodide, less than about 8 weight % water and about 0.5 to about 30 weight percent methyl acetate. The crude acetic acid is flashed and further purified. This process is stable in the absence of a lithium iodide cocatalyst, or in low concentrations of lithium iodide, with an STY greater than 10 mol/L/hr. | 2013-04-25 |
| 20130102811 | PROCESS FOR THE PREPARATION OF LACOSAMIDE - The present invention relates to a novel and improved process for the preparation of lacosamide, wherein the process is a sequential one-pot process. | 2013-04-25 |
| 20130102812 | WATER-SOLUBLE FLUORESCENT FULLERENE DERIVATIVE, AND PREPARATION METHOD THEREOF - The present invention relates to a water-soluble fluorescent fullerene derivative and a preparation method thereof, and more particularly to a method of preparing a fullerene derivative having excellent fluorescence in a simple manner by mixing fullerene and a ligand containing a terminal hydroxyl group in a first solvent and reacting the mixture in the presence of a catalyst, and to a water-soluble fluorescent fullerene derivative prepared by the method. | 2013-04-25 |
| 20130102813 | METHODS AND APPARATUS FOR SYNTHESIS OF ALCOHOLS FROM SYNGAS - This invention provides a method for producing ethanol and 2-propanol from syngas, the method comprising: (a) converting syngas into methanol using a methanol-synthesis catalyst; (b) converting methanol into ethylene and propylene using a methanol-to-olefins catalyst; and (c) hydrating ethylene into ethanol and propylene into 2-propanol. As taught herein, the combined yield of the ethanol and the 2-propanol from biomass can be at least 100 gallons per dry ton biomass. In certain embodiments, the yield of ethanol is at least 100 gallons per dry ton biomass. In some embodiments, the yield of 2-propanol is at least 50 gallons per dry ton biomass. | 2013-04-25 |
| 20130102814 | PROCESSES FOR THE PRODUCTION OF FLUOROPROPANES AND HALOPROPENES AND AZEOTROPIC COMPOSITIONS OF 2-CHLORO-3,3,3-TRIFLUORO-1-PROPENE WITH HF AND OF 1,1,1,2,2-PENTAFLUOROPROPANE WITH HF - A process is disclosed for making CF | 2013-04-25 |
| 20130102815 | Process - The invention provides a process for the preparation of 2,3,3,3-tetrafluoropropene (1234yf) comprising (a) contacting 1,1,1-trifluoro-2,3-difluoropropane (243db) with hydrogen fluoride (HF) in the presence of a zinc/chromia catalyst to produce a compound having the formula CF | 2013-04-25 |
| 20130102816 | METHOD FOR REDUCING THE VISCOSITY OF VISCOUS FLUIDS - A viscous fluid, such as heavy crude oil which is too viscous to enable it to be pumped from a flowing phase of a reservoir into and along a pipeline for delivery to a refinery or other storage facility, may be contacted with a formulation to reduce its viscosity. The formulation comprises a polymeric material AA which includes —O— moieties pendent from a polymeric backbone thereof and said material is optionally cross-linked. In one embodiment, the formulation may comprise polyvinyl alcohol. In an alternative embodiment, the formulation may comprise a cross-linked polymeric material, such as cross-linked polyvinyl alcohol. After the viscous composition has been transported to a desired location, it may be separated from the other components. | 2013-04-25 |
| 20130102817 | PROCESS TO PREPARE JET FUELS AND ITS PRODUCTS - A jet fuel containing a major amount of a synthetic paraffinic kerosene fuel component is provided by:
| 2013-04-25 |
| 20130102818 | PROCESS OF CONVERSION OF BIOMASS TO FUEL - The present invention is directed to processes for the direct conversion of lipidic biomass fuelstock to combustible fuels. In particular, the invention provides a process for the direct conversion of animal fats to transportations fuels suitable as replacement for petroleum-derived transportation fuels. In one embodiment, the method comprises the steps of hydrolyzing a lipidic biomass to form free fatty acids, catalytically deoxygenating the free fatty acids to form n-alkanes, and reforming at least a portion of the n-alkanes into a mixture of compounds in the correct chain length, conformations, and ratio to be useful transportation fuels. Particularly, the product prepared according to the invention comprises mixtures of hydrocarbon compounds selected from the group consisting of n-alkanes, isoalkanes, aromatics, cycloalkanes, and combinations thereof. | 2013-04-25 |
| 20130102819 | CATALYST COMPOSITION FOR SELECTIVE HYDROGENATION WITH IMPROVED CHARACTERISTICS - This invention relates to heterogeneous catalysts useful for selective hydrogenation of unsaturated hydrocarbons, comprising palladium and optionally a promoter, supported on a substrate, having an uncoated BET surface area of ≦9 m | 2013-04-25 |
| 20130102820 | PROCESSES AND SYSTEMS FOR THE STAGED SYNTHESIS OF ALKYL BROMIDES - Processes and systems for synthesizing hydrocarbon products, such as high molecular weight hydrocarbons, olefins or mixtures thereof, from alkyl bromides wherein one or more streams of alkyl bromides may be reacted in sequential or concurrent stages at different temperatures. The catalyst used in the synthesis stages may be the same or different and at least in one instance is chosen to form hydrocarbon products having a significant C | 2013-04-25 |
| 20130102821 | Processes and Systems for Separate, Parallel Methane and Higher Alkanes' Bromination - Process and systems for alkane bromination and, in one or more embodiments, to separate, parallel methane and higher alkanes bromination in a bromine-based process. An embodiment discloses a bromine-based process for converting alkanes to liquid hydrocarbons that includes alkanes bromination, the process comprising: brominating a methane stream comprising methane and having less than about 2 mol % of ethane to form methane bromination products comprising brominated methane and a first fraction of hydrogen bromide; separately brominating a C2+ alkane stream comprising an alkane having 2 or more carbon atoms to form C2+ methane bromination products comprising brominated alkanes having 2 or more carbon atoms and a second fraction of hydrogen bromide; and catalytically reacting at least a portion of the brominated methane and the brominated alkanes to form higher molecular hydrocarbons. | 2013-04-25 |
| 20130102822 | Process for the Production of Butadiene - Processes are provided for the production of butadiene from C | 2013-04-25 |
| 20130102823 | METHOD FOR PRODUCING OLEFINS - The present invention provides a method to produce olefins by the decarboxylation of organic carboxylic acids in the presence of an organopalladium catalyst. | 2013-04-25 |
| 20130102824 | PHOSPHORUS MODIFIED ZEOLITE CATALYSTS - A bound phosphorus-modified catalyst composition comprises a zeolite having a silica to alumina molar ratio of at least 40, phosphorus in an amount between about 0.1 wt % and about 3 wt % of the total catalyst composition, and a binder essentially free of aluminum. The bound catalyst composition can advantageously exhibit at least one of: (a) microporous surface area of at least 340 m | 2013-04-25 |
| 20130102825 | PHOSPHORUS MODIFIED ZEOLITE CATALYSTS - The invention relates to a bound phosphorus-modified catalyst composition comprising a zeolite having a silica to alumina molar ratio of at least 40 and a binder having a surface area less than 200 m | 2013-04-25 |
| 20130102826 | Systems And Methods For Generating Alpha Olefin Oligomers - Methods for preparing selected oligomers from monomers utilize systems of equipment adapted to provide desired compositions in various streams. Representative equipment of an oligomerization system includes an oligomer synthesis reactor and, optionally, a gas/liquid phase separation system. A monomer feed stream and a catalyst feed stream are directed to the oligomer synthesis reactor. The reactor produces a vapor phase effluent and a liquid phase effluent. The selected oligomer product is withdrawn from the vapor phase effluent. When the gas/liquid phase separation system is included, it is adapted to form a first recycle stream and a separator product stream from the vapor phase effluent. The separator product stream includes the desired oligomer product. Additional equipment may be utilized to further refine the vapor phase effluent and/or the final product stream. | 2013-04-25 |
| 20130102827 | METHOD FOR TREATING A CRACKED GAS STREAM FROM A HYDROCARBON PYROLYSIS INSTALLATION AND INSTALLATION ASSOCIATED THEREWITH - This method includes the separation of an upstream partly condensed cracked gas stream in an intermediate separator ( | 2013-04-25 |
| 20130102828 | Process to Decrease or Eliminate Corrosion from the Decomposition of Halide Containing Olefin Cataysts - A process is provided to inhibit or limit the decomposition of a halide-containing olefin oligomerization catalyst system during recovery of an oligomerization product. The process includes deactivation of an olefin oligomerization catalyst system present in an olefin oligomerization reactor effluent stream by contact with an alcohol under conditions that minimize potential for deactivated catalyst system decomposition. Such conditions include minimization of the water content of the deactivation agent and concentration of the deactivation agent. | 2013-04-25 |
| 20130102829 | METHOD FOR TREATING OSTEOSARCOMA BY BORON NEUTRON CAPTURE THERAPY USING BORIC ACID AS A BORON DRUG - The present invention provides a treatment of osteosarcoma by boron neutron capture therapy using boric acid as a single boron drug. | 2013-04-25 |
| 20130102830 | SYSTEM AND METHOD FOR ESTIMATING AND MANIPULATING ESTIMATED RADIATION DOSE - Methods are provided for permitting manipulation of an achievable dose distribution estimate deliverable by a radiation delivery apparatus for proposed treatment of a subject. One such method comprises: determining a dose modification voxel for which it is desired to modify the dose value and a corresponding magnitude of desired dose modification; for each of a plurality of beams: (i) characterizing the beam as a two-dimensional array of beamlets, wherein each beamlet is associated with a corresponding intensity value and a ray line representing the projection of the beamlet into space; and (ii) identifying one or more dose-change beamlets which have associated ray lines that intersect the dose modification voxel; modifying the intensity values of at least one of the dose-change beamlets; and updating the achievable dose distribution estimate to account for the modified intensity values of the at least one of the dose-change beamlets. | 2013-04-25 |
| 20130102831 | REAL-TIME RADIATION TREATMENT PLANNING SYSTEM - The invention relates to a real time radiation treatment planning system for use in effecting radiation therapy of a pre-selected anatomical portion of an animal body using hollow needles. According to embodiments of the invention, the system may include a processing means processing means-configured to perform a three-dimensional imaging algorithm and a three-dimensional image segmentation algorithm, with respect to one or more specific organs within the pre-selected anatomical portion and with respect to the needles, for converting the image data obtained with an imaging means into a three-dimensional image of the anatomical portion, using at least one single or multi-objective anatomy-based genetic optimization algorithm. For pre-planning or virtual simulation purposes, the processing means is arranged to determine in real time the optimal number and position of at least one of the needles, positions of energy emitting sources within the needles, and the dwell times of the energy emitting sources at the positions. For post-planning purposes, the processing means is arranged to determine, based on three-dimensional image information, in real time the real needle positions and the dwell times of the energy emitting sources for the positions. | 2013-04-25 |
| 20130102832 | BRACHYTHERAPY DEVICES AND RELATED METHODS HAVING MICROENCAPSULATED BRACHYTHERAPY MATERIALS - A brachytherapy device includes a bioabsorbable support and a plurality of microcapsules on the support. Each of the plurality of the microcapsules includes a plurality of microspheres and a bioabsorbable microcapsule wall that encloses the plurality of microspheres. The plurality of microspheres includes radiation-emitting microspheres comprising a radioactive material, radio-opaque microspheres comprising a radio-opaque material or a combination thereof. | 2013-04-25 |
| 20130102833 | MODULATION AND ANALYSIS OF CEREBRAL PERFUSION IN EPILEPSY AND OTHER NEUROLOGICAL DISORDERS - A system including an implantable neurostimulator device capable of modulating cerebral blood flow to treat epilepsy and other neurological disorders. In one embodiment, the system is capable of modulating cerebral blood flow (also referred to as cerebral perfusion) in response to measurements and other observed conditions. Perfusion may be increased or decreased by systems and methods according to the invention as clinically required. | 2013-04-25 |
| 20130102834 | SLIDE DEVICE, MECHANICAL SEAL, ROTARY DEVICE, PUMP AND AUXILIARY ARTIFICIAL HEART SYSTEM - Provided is a slide device which can reduce a frictional force more than a conventional slide device when used in an aqueous liquid containing a blood component. In a slide device which includes: a fixed-side slide member having a slide surface; and a rotary-side slide member having a slide surface, the slide device being used in an aqueous liquid containing a blood component in a state where the slide surface of the fixed-side slide member and the slide surface of the rotary-side slide member face each other in an opposed manner, at least one of the fixed-side slide member and the rotary-side slide member is formed of a member which is made of a material which contains silicon and has hydrate of silicon oxide on the slide surface thereof. | 2013-04-25 |
| 20130102835 | ANISOTROPIC REINFORCEMENT AND RELATED METHOD THEREOF - Anisotropic reinforcements and synthetic materials are provided in which the fibers, mesh, weave, or otherwise interlaced or networked components thereof are oriented in one direction so as to create greater stiffness and/or tension in the one direction of the patch relative to other directions of the reinforcement. Methods of producing such anisotropic reinforcements are provided. The anisotropic reinforcements are advantageously suitable for the surgical repair of incisions, openings, defects, etc. of the cardiovascular system and allow healing to occur while preserving mechanical function, particularly ventricular function. | 2013-04-25 |
| 20130102836 | System and Method for Reorienting and Decreasing Patient Anxiety in a Medical Facility - A computer system for reorienting, reducing anxiety, and/or reducing delirium risk of a patient in a hospital is provided. The computer has a central processing unit (CPU) for executing machine instructions for a passive and active module and a memory for storing the machine instructions. The machine instructions implement functions when executed by the CPU. Patient-specific content is inputted into the CPU. The system then communicates the patient-specific content from the CPU to the patient by displaying and looping the patient-specific content such that any point of the loop of the patient-specific content helps reorient and reduce anxiety and delirium risk. | 2013-04-25 |
| 20130102837 | EMBRYO QUALITY ASSESSMENT BASED ON BLASTOMERE DIVISION AND MOVEMENT - The invention concerns a system and method for determining embryo quality comprising monitoring the embryo for a time period, said time period having a length sufficient to comprise at least one cell division period and at least a part of an inter-division period, and determining the length of the at least one cell division period; and/or ii) determining the extent and/or spatial distribution of cellular or organelle movement during the cell division period; and/or iii) determining duration of an inter-division period; and/or iv) determining the extent and/or spatial distribution of cellular or organelle movement during the inter-division period thereby obtaining an embryo quality measure. Thus, the selection of optimal embryos to be implanted after in vitro fertilization (IVF) is facilitated based on the timing, duration, spatial distribution, and extent of observed cell divisions and associated cellular and organelle movement. | 2013-04-25 |
| 20130102838 | Oocyte Spindle-Associated Factors Improve Somatic Cell Cloning - The invention pertains to the discovery that the presence of oocyte spindle associated factors in an enucleated oocyte improves oocyte quality and subsequently nuclear transfer. In particular, it was discovered that maintaining oocyte spindle factors in the oocyte after enucleation improves oocyte quality for use in nuclear transfer methodology. | 2013-04-25 |
| 20130102839 | Methods for Making a Supported Graft - A method for preparing a stent-graft for intraluminal delivery, including positioning an expanded polytetrafluoroethylene (ePTFE) substrate over a support mandrel, coupling a shape memory member to a polymer cladding to form a polymer clad member, winding the polymer clad member in an overlapping helical manner onto a surface of the ePTFE substrate, joining and sealing adjacent overlapping regions of the polymer clad member together and to the surface of the ePTFE substrate to form a stent-graft, manipulating the stent-graft from a larger first diameter to a smaller second diameter, and loading the stent-graft into a restraining sheath at the smaller second diameter. | 2013-04-25 |
| 20130102840 | IMPLANTABLE INJECTION PORT - Injection ports are disclosed for use with a gastric band for the treatment of obesity. An injection port may include a septum having a top surface, a bottom surface, and a side wall connecting the top surface to the bottom surface. The injection port may also include a housing including a first inner side wall being tapered inwards such that an opening defined at a first end is larger than an opening defined at a second end, the tapering of the first inner side wall being used to secure the septum within the housing. The housing may further include a second inner side wall having a first end and a second end, the first end of the second inner side wall joined to the second end of the first inner side wall, and a bottom surface joined to the second end of the second inner side wall. | 2013-04-25 |
| 20130102841 | METHOD AND APPARATUS FOR ENDOSCOPICALLY TREATING RECTAL PROLAPSE - A method for treating rectal prolapse, the method comprising: inserting a rectum-gripping and advancement apparatus into a prolapsed rectum via the anus; maneuvering the rectum-gripping and advancement apparatus so that the rectum-gripping and advancement apparatus securely engages the rectum; advancing the rectum-gripping and advancement apparatus distally so as to return the prolapsed rectum to its normal, non-prolapsed state; and securing the rectum to supporting tissue whereby to retain the rectum in its normal, non-prolapsed state. | 2013-04-25 |
| 20130102842 | RECONFIGURABLE FURNITURE - An article of reconfigurable furniture is provided including a plurality of cushions, at least some of which are generally triangular in cross-section, the cushions being dimensioned to be stackable in a cube. A cube shaped cube cover is provided for covering said cushions when said cushions are stacked into said cube. The cushions are covered by cushion covers having interactive engagement elements for releasably securing said cushions one to another to provide at least one contoured support surface for supporting a user thereon in at least one selected pose. | 2013-04-25 |
| 20130102843 | JAWED TROCAR ASSEMBLY - A trocar assembly is presented herein. The trocar assembly can have a hollow elongate member having a first end and a second end. The first end of the hollow elongate member can be open. The first end also can allows an implement to be inserted. The trocar assembly also includes a jaw hingedly coupled to the second end of the hollow elongate member. | 2013-04-25 |
| 20130102844 | CASING OF CAPSULE ENDOSCOPE, CAPSULE ENDOSCOPE KIT, ASSEMBLY METHOD OF CAPSULE ENDOSCOPE KIT AND ASSEMBLY DEVICE OF CAPSULE ENDOSCOPE KIT - An inner casing according to the present invention includes a hole which is a holding portion that is provided at the center of a base portion having a planar shape so as to protrude in a direction orthogonal to a principal surface of the base portion and hold a capsule endoscope and a plurality of step portions each protruding from a side surface of the hole and abutting on an area of an outer surface of a hemispheric dome portion, which is located inside an optical viewing angle of the capsule endoscope and which does not contribute to generation of an image captured by the capsule endoscope to realize alignment in a longitudinal direction of the capsule endoscope. | 2013-04-25 |
| 20130102845 | CAPSULE-TYPE MEDICAL APPARATUS AND METHOD OF MANUFACTURING CAPSULE-TYPE MEDICAL APPARATUS - The present invention provides a capsule-type medical apparatus and a method of manufacturing a capsule-type medical apparatus which can prevent a contact between a burr formed on an optical dome which is a part of a capsule-like casing and a living body in a subject. The capsule-type medical apparatus has a capsule-like casing which can be introduced inside the subject. The casing is configured with optically transparent optical domes and a cylindrical trunk member having an outer diameter dimension larger than an outer diameter dimension of the optical domes. The cylindrical trunk member is fitted onto an outer circumferential surface of the optical domes so as to cover each of the optical domes up to a portion near the burr formed thereon. The cylindrical trunk member has a step higher than the burr so as to prevent a contact between the burr and a living body in the subject. | 2013-04-25 |
| 20130102846 | STEERABLE ELECTRONIC STEREOSCOPIC ENDOSCOPE - A steerable stereoscopic endoscope comprising:
| 2013-04-25 |
| 20130102847 | ATTACHMENT UNIT, ENDOSCOPIC INSERTION SECTION AND ENDOSCOPE - An endoscope includes an attachment unit detachably attached to an outer peripheral direction side of an insertion section to be rotatable about a longitudinal axis with respect to an insertion main body, and including a gear portion formed over an all-round inner peripheral portion of the attachment unit, a rotary gear meshing with the gear portion to allow the attachment unit to be attached to the insertion section, and a base portion defining a gear arrangement portion where the rotary gear is arranged on an outer peripheral portion of the insertion section. In the endoscope, a channel, extended through an inside of an operation section and an inside of the insertion section from an outer surface of the operation section and opened to an outside of the insertion section in the gear arrangement portion, is defined. | 2013-04-25 |
| 20130102848 | ATTACHMENT UNIT AND ENDOSCOPE - An attachment unit includes a tube main body extended along a longitudinal axis in a state that a gap is provided between itself and an outer peripheral portion of an insertion section or a member on the outer peripheral portion of the insertion section, and a tube proximal end portion, provided to a proximal direction side of the tube main body, to which a proximal end of the attachment unit is placed. The tube proximal end portion includes a proximal side gap reducing portion eliminating or reducing the gap as compared with a part to an inner peripheral direction side of the tube main body between itself and the outer peripheral portion of the insertion section or the member, and is placed to a distal direction side of an insertion opening in a use situation. | 2013-04-25 |
| 20130102849 | DEPLOYMENT METHODS AND MECHANISMS FOR MINIMALLY INVASIVE IMPLANTATION OF HEART CONTACTING CARDIAC DEVICES - The present invention provides methods, systems, kits, and devices that aid in the positioning of a direct cardiac compression device about the heart. | 2013-04-25 |
| 20130102850 | RETRACTOR EXTENSIONS AND METHODS OF USE - A retractor extension is provided comprising a body having a distal end and a proximal end extending longitudinally from the distal end, the distal end of the body comprising a first set of engagement members comprising a first projection configured for attaching the body to a first end surface of the retractor, the proximal end of the body comprising a second set of engagement members comprising a second projection configured for attaching the body to a second end surface of the retractor. In some embodiments, the retractor extension holds tissue away from the surgical incision to enhance the surgeon's field of vision. Methods of attaching the retractor extension to the retractor are also described. | 2013-04-25 |
| 20130102851 | HOLDING ARRANGEMENT FOR A SURGICAL ACCESS SYSTEM - Holding arrangements for a surgical access assembly are disclosed. One holding arrangement includes a body portion, an engagement barrel and a retaining member. The retaining member is configured as a hook at a distal end of the body portion and is sized to partially encircle a portion of an outer sheath. The engagement barrel is position on a proximal end of the body portion and is configured to be operatively connected to a surgical holding arrangement. | 2013-04-25 |
| 20130102852 | CONTROLLING DEVICES BASED ON PHYSIOLOGICAL MEASUREMENTS - Embodiments of the invention control a device based on physiological measurements associated with a user. A determination is made that a user has manually adjusted a controlled device. A context associated with the user is identified in response to determining that the user has manually adjusted the controlled device. A change is detected in at least one physiological measurement associated with the user in response to the controlled device being manually adjusted. A target physiological measurement associated with at least one physiological measurement is modified based on the change that has been detected. The context that has been identified is associated with the target physiological measurement that has been modified. | 2013-04-25 |
| 20130102853 | INTEROPERABILITY ENHANCEMENT THAT SUPPORTS CONNECTIVITY OF APPLICATIONS ON A MEDICAL DEVICE - A diabetes management system is provided that supports connectivity of applications residing on a medical device. The diabetes management system includes a medical device that performs a diabetes care function in relation to a patient and a diabetes care management device in data communication with the medical device. The diabetes care management device is comprised generally of a connection management module and at least one application separate from the connection management module. The connection management module is configured to receive an associate request from the medical device and operable to establish a data connection with the medical device in accordance with IEEE standard 11073, such that the applications interacts with the connection management module to communicate via the data connection with the medical device. | 2013-04-25 |
| 20130102854 | MENTAL STATE EVALUATION LEARNING FOR ADVERTISING - Analysis of mental states is performed as people view advertisements. Advertisement effectiveness is evaluated based on the analyzed mental states. Learning is then performed to determine the most effective ways to evaluate mental states based on the evaluation methods' ability to project advertisement effectiveness. Effectiveness descriptors are evaluated and statistics are assembled for the advertisements. One or more effectiveness classifiers are determined. Based on the effectiveness descriptors and classifiers, advertisement effectiveness is projected. | 2013-04-25 |
| 20130102855 | BODE INDEX MEASUREMENT - A computer-implemented system and method for determining a BODE index value for a patient is provided. The method includes using a Body Mass Index (BMI) measuring device to obtain BMI data. An airway obstruction measuring device measures airway obstruction of the patient to obtain airway obstruction data. A respiration rate sensor measures a respiration rate of the patient and to obtain respiration rate data. An activity monitor measures physical activity of the patient and to obtain physical activity data. A processor executes a computer program module to determine the BODE index value for the patient based on the Body Mass Index data, the airway obstruction data, the respiration rate data, and the physical activity data. | 2013-04-25 |
| 20130102856 | NON-INVASIVE DETECTION OF FETAL OR MATERNAL ILLNESS - The invention provides a non-invasive method for diagnosing a biological condition in a pregnant female, or fetus therein, by measuring fetal electrical activity using a plurality of contact elements. Each contact element is configured for attachment to an external skin surface and includes a plurality of electrodes configured in a unique pattern. The measured fetal electrical activity is compared to one or more references to determine a biological condition in the pregnant female, the fetus, or both. | 2013-04-25 |
| 20130102857 | NON-INVASIVE FETAL MONITORING - A non-invasive fetal monitoring system includes a plurality of contact elements, each of the contact elements comprising a plurality of electrodes configured in a unique pattern. The plurality of contact elements are configured for attachment to an external skin surface of a pregnant female for detecting fetal and/or maternal electrical activity. | 2013-04-25 |
| 20130102858 | IMPLANTABLE SENSOR DEVICE AND SYSTEM - The implantable medical device for measuring pressure is disclosed. The implantable medical device is connectable to a medical lead and comprises an outer sheath and a helically shaped needle arranged at the outer sheath. A pressure sensing body having a distal part is movably arranged in the outer sheath. The pressure sensing body is arranged such that the distal part is located within the outer sheath in an initial state of the pressure sensing body, wherein the pressure sensing body is arranged to be advanced from the initial state to protrude from the outer sheath and such that it is at least partially surrounded by the helically shaped needle; and a pressure sensor arranged at or adjacent to the distal part of the pressure sensing body for sensing pressure. | 2013-04-25 |
