16th week of 2013 patent applcation highlights part 44 |
Patent application number | Title | Published |
20130096147 | Raltegravir Salts and Crystalline Forms Thereof - The present invention includes new salts of Raltegravir and crystalline forms thereof, pharmaceutical compositions containing the salts or crystalline forms, methods of using the salts or crystalline forms or the compositions to treat HIV infection or to prepare medicament for treating HIV infection, and a process for preparing Raltegravir potassium. | 2013-04-18 |
20130096148 | PROCESS FOR ETRAVIRINE INTERMEDIATE AND POLYMORPHS OF ETRAVIRINE - 4-[[6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-benzonitrile is a key intermediate for the preparation of etravirine. The present invention provides a process for preparation of 4-[[6-chloro-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile. The present invention also provides a novel process for the preparation of etravirine crystalline form I. The present invention further provides novel crystalline forms of etravirine, processes for their preparation and pharmaceutical compositions comprising them. | 2013-04-18 |
20130096149 | HETEROARYL COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS - The present invention provides compounds of Formula I: | 2013-04-18 |
20130096150 | Substituted Azoanthracene Derivatives, Pharmaceutical Compositions, and Methods of Use Thereof - The present invention is directed to substituted azoanthracene derivatives or pharmaceutically acceptable salts thereof that modulate the human GLP-1 receptor and that may be useful in the treatment of diseases, disorders, or conditions in which modulation of the human GLP-1 receptor is beneficial, such as diabetes mellitus type 2. The invention is also directed to pharmaceutical compositions comprising these compounds and to the use of these compounds and compositions in the treatment of such diseases, disorders, or conditions in which modulation of the human GLP-1 receptor is beneficial. | 2013-04-18 |
20130096151 | NOVEL COMBINATION AND USE - The present invention relates to the use of an anesthetic agent for killing clinically latent microorganisms associated with microbial infections and to novel combinations comprising an anesthetic agent and an antimicrobial agent for the treatment of microbial infections. | 2013-04-18 |
20130096152 | NOVEL SALTS OF 6-HETEROCYCLE SUBSTITUTED HEXAHYDROPHENANTHRIDINE DERIVATIVES - Disclosed herein are salts of 6-heteroaryl substituted hexahydrophenanthridine PDE4 inhibiting compounds, which can be used in the pharmaceutical industry for the production of pharmaceutical compositions. | 2013-04-18 |
20130096153 | METHODS AND COMPOSITIONS FOR THE ASSESSMENT OF DRUG RESPONSE - The present invention provides methods for predicting or determining a subject's response to an antiplatelet agent, and methods for determining a subject's suitability to a treatment regime or intervention for a disease associated with platelet aggregation, using analysis of genetic polymorphisms. The present invention also relates to the use of genetic polymorphisms in assessing a subject's response to an antiplatelet agent. Nucleotide probes and primers, kits, and microarrays suitable for such assessment are also provided | 2013-04-18 |
20130096154 | METHODS AND COMPOSITIONS FOR THE ASSESSMENT OF DRUG RESPONSE - The present invention provides methods for predicting or determining a subject's response to an antiplatelet agent, and methods for determining a subject's suitability to a treatment regime or intervention for a disease associated with platelet aggregation, using analysis of genetic polymorphisms. The present invention also relates to the use of genetic polymorphisms in assessing a subject's response to an antiplatelet agent. Nucleotide probes and primers, kits, and microarrays suitable for such assessment are also provided | 2013-04-18 |
20130096155 | TRIAZOLOPYRIDINE COMPOUND, AND ACTION THEREOF AS PROLYL HYDROXYLASE INHIBITOR OR ERYTHROPOIETIN PRODUCTION-INDUCING AGENT - The present invention provides a triazolopyridine compound having a prolyl hydroxylase inhibitory action and an erythropoietin production-inducing ability. The present invention relates to a compound represented by the following formula [I]: | 2013-04-18 |
20130096156 | QUINOLINE DERIVATIVES AS FUNGICIDES - Compounds of the general formula (I) wherein the substituents are as defined in claim | 2013-04-18 |
20130096157 | QUINOLINE DERIVATIVES AND USES OF THE SAME - Provided is a quinoline derivative of Chemical Formula (I): | 2013-04-18 |
20130096158 | Treatment Of Multiple Sclerosis With Combination Of Laquinimod And Fingolimod - This invention provides a method of treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising administering to the subject laquinimod as an add-on therapy to or in combination with fingolimod. This invention also provides a package and a pharmaceutical composition comprising laquinimod and fingolimod for treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention also provides laquinimod for use as an add-on therapy or in combination with fingolimod in treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention further provides use of laquinimod and fingolimod in the preparation of a combination for treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome. | 2013-04-18 |
20130096159 | INHIBITORS OF HUMAN 12-LIPOXYGENASE - Disclosed are inhibitors of human 12-lipoxygenase of Formula (I) or (II), wherein R | 2013-04-18 |
20130096160 | ARYLTHIAZOLYL PIPERIDINES AND RELATED COMPOUNDS AS MODULATORS OF SURVIVAL MOTOR NEURON (SMN) PROTEIN PRODUCTION - Aryl substituted thiazol-2-yl-piperidines and related compounds useful as modulators of survival motor neuron (SMN) protein production are provided herein. Without being bound to any particular theory it is believed the aryl substituted thiazol-2-yl-piperidines and related compounds provided herein act to increase production of the SMN2 form of survival motor neuron protein. These compounds are useful for treating spinal muscular atrophy. Pharmaceutical compositions containing a carrier and one or more of the aryl substituted thiazol-2-yl-piperidine or related compounds described herein are also provided. Methods of treating spinal muscular atrophy are also provided by this disclosure. | 2013-04-18 |
20130096161 | Novel Dihydropyridin-2(1H)-One Compounds as S-Nitrosoglutathione Reductase Inhibitors and Neurokinin-3 Receptor Antagonists - The present invention is directed to novel dihydropyridin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors and/or Neurokinin-3 (NK3) receptor antagonists, pharmaceutical compositions comprising such compounds, and methods of making and using the same. | 2013-04-18 |
20130096162 | DUAL-ACTING ANTIHYPERTENSIVE AGENTS - The invention is directed to compounds having the formula: | 2013-04-18 |
20130096163 | Injectable dosage form of flupirtine - The present invention relates to a flupirtine-containing lyophilisate, the use of this lyophilisate to produce a pharmaceutical composition to be parenterally applied, a procedure to produce a flupirtine-containing pharmaceutical composition to be parenterally applied, and a procedure to produce the flupirtine-containing lyophilisate as well as the flupirtine-containing pharmaceutical composition produced using the lyophilisate. For this purpose a lyophilisate is provided which contains the active ingredient flupirtine in the form of a physiologically tolerated salt, which has a solubility in water of at least 2.5 mg/ml, preferably at least 5 mg/ml, especially preferably at least 10 mg/ml, and contains one or more cyclodextrins or cyclodextrin derivatives, and which may be used to produce a pharmaceutical composition to be parenterally applied. | 2013-04-18 |
20130096164 | USE OF A 1-N-(HALO-3-PYRIDYLMETHYL)-N-METHYLAMINO-1-ALKYLAMINO-2-NITROETHY- LENE DERIVATIVE FOR PREPARING A TOPICAL VETERINARY PHARMACEUTICAL COMPOSITION FOR COMBATING EXTERNAL PARASITES - The present invention relates to the use, as active ingredient, of a 1-N-(halo-3-pyridylmethyl)-N-methylamino-1-alkylamino-2-nitroethylene derivative for preparing a veterinary pharmaceutical composition for topical application in the treatment of external parasites, in particular fleas, in domestic animals, in particular in dogs and cats, intended to be applied at least every 2 weeks. | 2013-04-18 |
20130096165 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS - The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with or mediated by G protein-coupled receptors, in particular G protein-coupled receptor 120. | 2013-04-18 |
20130096166 | CAMALEXIN AS A TREATMENT FOR PROSTATE CANCER - Compositions and methods to treat prostate cancer with the compound camalexin and its structural analogs. Camalexin increases ROS production and decreases the proliferation of prostate cancer cells, especially aggressive prostate cancer cells. | 2013-04-18 |
20130096167 | METHODS FOR PRESERVING TECHNICAL PRODUCTS SUCH AS FUELS AND LUBRICANTS WITH A MICROBICIDAL COMPOSITION - Methods for preserving technical products such as fuels and lubricants with a microbicidal composition. The composition is made up of at least one formaldehyde donor compound and at least one antioxidant. The antioxidant is either a gallic ester, a phenol derivative, a L-ascorbic acid, including salts and derivatives thereof, a tocopherol or one of its associated derivatives. | 2013-04-18 |
20130096168 | Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors - The present invention provides a compound of formula I; | 2013-04-18 |
20130096169 | TREATMENT OF CANCER WITH BIO AND CHEMOTHERAPY - This invention relates to compositions and methods utilizing a chemotherapeutic drug and 6-bromoindirubin3′-oxime (BIO) for the treatment of cancer, including glioblastoma multiforme. The present invention demonstrates that BIO works synergistically with chemotherapeutic drugs to increase the cytotoxic effects of these drugs in glioma cells. | 2013-04-18 |
20130096170 | METHODS OF TREATING PEDIATRIC PATIENTS USING DEXMEDETOMIDINE - The presently disclosed subject matter relates to methods of administering an effective amount of dexmedetomidine to a pediatric patient in order to reduce the incidence of neurological damage. More particularly, the presently disclosed subject matter relates to methods of providing sedation or analgesia to a pediatric patient by administering a dexmedetomidine infusion and optionally a loading dose. The dexmedetomidine can be administered before, during, or after surgery. | 2013-04-18 |
20130096171 | METHODS OF TREATING PEDIATRIC PATIENTS USING DEXMEDETOMIDINE - The presently disclosed subject matter relates to methods of administering an effective amount of dexmedetomidine to a pediatric patient in order to reduce the incidence of neurological damage. More particularly, the presently disclosed subject matter relates to methods of providing sedation or analgesia to a pediatric patient by administering a dexmedetomidine infusion and optionally a loading dose. The dexmedetomidine can be administered before, during, or after surgery. | 2013-04-18 |
20130096172 | METHODS OF TREATING PEDIATRIC PATIENTS USING DEXMEDETOMIDINE - The presently disclosed subject matter relates to methods of administering an effective amount of dexmedetomidine to a pediatric patient in order to reduce the incidence of neurological damage. More particularly, the presently disclosed subject matter relates to methods of providing sedation or analgesia to a pediatric patient by administering a dexmedetomidine infusion and optionally a loading dose. The dexmedetomidine can be administered before, during, or after surgery. | 2013-04-18 |
20130096173 | MOLECULAR GENETIC APPROACH TO TREATMENT AND DIAGNOSIS OF ALCOHOL AND DRUG DEPENDENCE - The present invention provides compositions and methods useful for diagnosing, treating, and monitoring alcohol dependence and disorders and susceptibility to alcohol dependence disorders, as well as drug related dependence and disorders. | 2013-04-18 |
20130096174 | PLANT DISEASE CONTROL COMPOSITION AND METHOD OF CONTROLLING PLANT DISEASE - A plant disease control composition comprising a carboxamide compound represented by formula (I) whose enantiomer ratio R form/S form of the carboxamide compound is 80/20 or more has an excellent plant disease controlling activity. | 2013-04-18 |
20130096175 | Compounds and Methods for Altering Lifespan of Eukaryotic Organisms - Provided are compounds which generally have a triketone structure. Examples of the compounds include derivatives of 1,3-cyclohexanedione, such as: 1,3-cyclohexanedione, 2-propanoyl-5-cyclohexyl-; 1,3-cyclohexanedione, 2-propanoyl-5-[4-fluorophenyl]-; 1,3-cyclohexanedione, 2-acetyl-5-[thien-2-yl]-; 1,3-cyclohexanedione, 2-acetyl-5-butyl-; and 1,3-cyclohexanedione, 2-propanoyl-5-[bicyclo[2.2.1]hept-2-en-5-yl]-. The compounds can be used to alter the lifespan of eukaryotic organisms and treat inflammation. | 2013-04-18 |
20130096176 | MODULATION OF INSULIN LIKE GROWTH FACTOR I RECEPTOR EXPRESSION - The present invention provides compositions and methods for modulating the expression of growth factor gene. In particular, this invention relates to compounds, particularly oligonucleotide compounds, which, in preferred embodiments, hybridize with nucleic acid molecules encoding the Insulin Like Growth Factor I receptor (IGF-I receptor or IGF-IR) and in particular human IGF-IR. Such compounds are exemplified herein to modulate proliferation which is relevant to the treatment of proliferative and inflammatory skin disorders and cancer. It will be understood, however, that the compounds can be used for any other condition in which the IGF-IR is involved including inflammatory condition. | 2013-04-18 |
20130096177 | POLYMERS FOR DELIVERING MOLECULES OF INTEREST - The present invention relates to a new class of cationic polymers that self-assemble with a pH-sensitive dissolution switch, and their uses to deliver molecules of interest to a cell. The present invention also relates to compositions comprising said cationic polymers non-covalently associated with a molecule of interest, in particular with a siRNA. | 2013-04-18 |
20130096178 | GENETIC MARKERS FOR PAGET'S DISEASE - The present invention is based on the identification of a number of genetic markers that are associated with susceptibility to Paget's disease of bone (PDB). This invention provides details of markers and nucleotide sequences as well as associated proteins/peptides and/or compositions and methods, for use in treating, preventing and/or detecting/diagnosing PDB and/or a susceptibility/predisposition thereto. | 2013-04-18 |
20130096179 | SIRT4 ACTIVITIES - Methods of modulating insulin secretion and treating metabolic disorders by modulating the expression or activity of Sirt4 are provided. | 2013-04-18 |
20130096180 | Bispecific Antisense Oligonucleotides that Inhibit IGFBP-2 and IGFBP-5 and Methods of Using Same - Bispecific antisense oligonucleotides which consist essentially of a sequence of bases that is complementary to portions of both the gene encoding human IGFBP-2 and the gene encoding human IGFBP-5 are useful in as antisense therapeutics in the treatment of endocrine-regulated cancers. | 2013-04-18 |
20130096181 | METHODS OF USING SCD1 ANTAGONISTS - Provided herein are therapies for the treatment of pathological conditions, such as cancer, and method of using SCD1 antagonists. | 2013-04-18 |
20130096182 | RECOMBINANT ADENO-ASSOCIATED VECTORS FOR TARGETED TREATMENT - Novel adeno-associated virus (AAV) vectors in nucleotide and amino acid forms and uses thereof are provided. The isolates show specific tropism for certain target tissues, such as blood stem cells, liver, heart and joint tissue, and may be used to transduce stem cells for introduction of genes of interest into the target tissues. Certain of the vectors are able to cross tightly controlled biological junctions, such as the blood-brain barrier, which open up additional novel uses and target organs for the vectors, providing for additional methods of gene therapy and drug delivery. | 2013-04-18 |
20130096183 | TREATMENT OF SODIUM CHANNEL, VOLTAGE-GATED, ALPHA SUBUNIT (SCNA) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO SCNA - The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Sodium channel, voltage-gated, alpha subunit (SCNA), in particular, by targeting natural antisense polynucleotides of Sodium channel, voltage-gated, alpha subunit (SCNA). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of SCNA. | 2013-04-18 |
20130096184 | NKX3-1 SARNA AND KLF4 SARNA AND USES THEREOF - The present disclosure provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a NKX3-1 gene product in a cell by contacting the cell with a small activating RNA (saRNA) molecule comprising a ribonucleic strand that is complementary to a promoter region sequence of the NKX3-1 gene. The present disclosure also provides compositions, pharmaceutical preparations, kits and methods for increasing expression of a KLF4 gene product in a cell by contacting the cell with a small activating RNA (saRNA) molecule comprising a ribonucleic strand that is complementary to a promoter region sequence of the KLF4 gene. | 2013-04-18 |
20130096185 | INACTIVATION OF miR-34a BY ABERRANT CpG METHYLATION IN CANCER - The present application refers to methods for cancer diagnosis and treatment, particularly in types of cancers associated with aberrant CpG methylation of the miR-34 | 2013-04-18 |
20130096186 | IDENTIFICATION OF MUTATIONS IN HERPES SIMPLEX VIRUS ENVELOPE GLYCOPROTEINS THAT ENABLE OR ENHANCE VECTOR RETARGETING TO NOVEL NON-HSV RECEPTORS - The invention provides modified HSV vectors that exhibit enhanced entry of cells, either through direct infection and/or lateral spread. In one aspect, HSV vectors of the present invention can directly infect cells through interaction with cell proteins other than typical mediators of HSV infection. In another aspect, the invention provides an HSV vector, which exhibits lateral spread in cells typically resistant to HSV lateral spread, such as cells lacking gD receptors. The invention further provides DNA encoding mutant forms of the HSV gB and gH glycoproteins, stocks of the inventive virus, and methods for effecting viral targeting and efficient entry of cells. The invention also pertains to the use of the inventive vectors for treating cancers. | 2013-04-18 |
20130096187 | PHARMACEUTICAL COMPOSITION FOR EXTERNAL USE - A pharmaceutical composition for external use, including: i) luliconazole represented by the following structural formula (1) and/or a salt thereof; and ii) crotamiton. | 2013-04-18 |
20130096188 | DOXEPIN TRANS ISOMERS AND ISOMERIC MIXTURES AND METHODS OF USING THE SAME TO TREAT SLEEP DISORDERS - The invention relates to use of the trans-(E) isomer or isomeric mixtures containing specified ratios of the trans-(E) and cis-(Z) isomers of doxepin, metabolites of doxepin, pharmaceutically-acceptable salts of doxepin and prodrugs of the same; compositions containing the same, for the treatment of sleep disorders | 2013-04-18 |
20130096189 | USE OF GLABRANIN FOR STIMULATING HAIR GROWTH - One of the major hair concerns for both men and women is that of hair loss. For men the most obvious manifestation of this is male pattern baldness known as alopecia areata. However hair shedding resulting in hair thinning is also a concern for both men and women. Individuals suffering hair loss often experience psychological disadvantages, for example social phobia, anxiety, and depression, due to their change in appearance. This invention relates to a hair care composition comprising glabranin or a derivative thereof. The invention also relates to a cosmetic method for increasing hair fibre diameter, stimulating hair growth, retaining hair or reducing hair loss, stimulating hair follicle growth in anagen or telogen phases, increasing hair fibre density and preventing or treating alopecia. | 2013-04-18 |
20130096190 | PERFLUOROCARBON GEL FORMULATIONS - A perfluorocarbon gel composition is disclosed with numerous uses including topical medical and cosmetic uses. | 2013-04-18 |
20130096191 | Benzonatate Compositions and Methods of Use - Oral dosage forms of benzonatate useful for anti-tussive and anti-tussive/combination applications. | 2013-04-18 |
20130096192 | NOVEL COMPOSITONS AND METHODS - Described herein are compositions (e.g., a pharmaceutical composition) and compounds of formula I, and their use in the treatment and/or prevention of diseases and disorders. | 2013-04-18 |
20130096193 | CREATINE BETA-ALANINATE: A NOVEL SALT FOR INCREASING ATHLETIC PERFORMANCE - Disclosed are creatine β-alaninate, compositions and formulations containing same, and methods of use therefor. | 2013-04-18 |
20130096194 | ANTIMICROBIAL ARTICLES - The present disclosure describes a method for forming microporous and antimicrobial articles. The method comprises preparing an initial composition containing a semicrystalline polylactic acid material, a nonpolymeric aliphatic ester diluent, and a nucleating agent. The initial composition is heated to form a melt blended composition. Upon cooling, the melt blended composition phase separates into a composition having two continuous phases. A network of interconnected micropores may be formed by stretching the composition, by removing at least a portion of the nonpolymeric aliphatic ester diluent from the composition, or a combination thereof. | 2013-04-18 |
20130096195 | THERAPEUTIC TREATMENT - The invention describes the use of betaine alone for treating and preventing arterites. The invention also describes an orally administered composition for treating arterites and, in particular, intermittent claudication, said composition containing, as an active ingredient, an active therapeutic quantity of betaine glycine by single dose. The invention particularly describes a medicament provided for treating a patient suffering from an intermittent claudication caused by peripheral circulatory disorders such as arteriosclerosis obliterans or by thromboangiitis obliterans. | 2013-04-18 |
20130096196 | PHARMACEUTICAL SEMI-SOLID COMPOSITION OF ISOTRETINOIN - An oral pharmaceutical composition of isotretinoin containing at least two lipidic excipients, one of them being hydrophilic (i.e. having an HLB value superior or equal to 10), the other being an oily vehicle | 2013-04-18 |
20130096197 | METHODS OF TREATING HYPERTRIGLYCERIDEMIA - In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof. | 2013-04-18 |
20130096198 | Tranexamic Acid Formulations - Disclosed are modified release oral tranexamic acid formulations and methods of treatment therewith. | 2013-04-18 |
20130096199 | BROMFENAC BIOAVAILABILITY - Formulations and methods that provided enhanced bromfenac penetration into ocular tissue when topically administered, compared to the currently available BROMDAY™ formulation and method when topically administered. The formulations and methods did so while retaining the patient convenience of a once-daily administration and advantageously lowered the bromfenac concentration dosed to the patient. | 2013-04-18 |
20130096200 | TREPROSTINIL TREATMENT FOR INTERSTITIAL LUNG DISEASE AND ASTHMA - The present invention describes methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of interstitial lung disease or asthma, or a condition, such as pulmonary fibrosis, associated with interstitial lung disease or a condition associated with asthma. The invention also relates to kits for treatment and/or prevention of such condition that include an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof. | 2013-04-18 |
20130096201 | Pharmaceutical Compositions Comprising Paracetamol and Process for Preparing The Same - Disclosed herein are injectable compositions containing high concentration of paracetamol or its pharmaceutically acceptable salts wherein the concentration of paracetamol or its pharmaceutically acceptable salt is >150 mg/ml in a judiciously tailored solvent system comprising glycofurol, ethanol, water or a solvent system comprising glycofurol, ethanol, polyethylene glycol, water. The viscosity of the said injectables is <28 cps. Further disclosed is the process for preparing the said injectables. The injectables can be administered by intramuscular route, intravenous route or as intravenous infusion after diluting in one of the routinely used intravenous fluids, infusion solutions of antibacterial, antifungal and amoebicidal drugs and along with anxiolytics (Midazolam injection) or narcotic analgesics (Fentanyl Citrate injection etc) as they remain stable, clear and transparent at least for 6 hours after dilution. | 2013-04-18 |
20130096202 | DISINFECTING AND STERILISING SOLUTIONS - The present invention relates to disinfecting and sterilising solutions containing glutaraldehyde. In particular, the invention provides solutions which are stabilised through the use of a unique combination of additives, including a bioflavonoid antioxidant (or other phenolic antioxidant) and an alkyl polyglucoside surfactant. | 2013-04-18 |
20130096203 | LOW TOXICITY TOPICAL ACTIVE AGENT DELIVERY SYSTEM - An active agent delivery composition is provided that allows topical delivery of active agents including vitamin A and its derivatives. A polyhalogenic vehicle such as methoxyonafluorobutane or ethoxyonafluorobutane serves as a coupler for an active agent and a silicone carrier so as to allow solubilization of active agents not normally miscible in silicones and providing a moisture maintaining composition. | 2013-04-18 |
20130096204 | Buffered Oxygen Therapeutic - An oxygen therapeutic composition, comprising a perfluorocarbon material, a viscosity modifier, a buffer, wherein the buffer stabilizes a pH of the composition at between about 6.5 to about 7.5, and wherein the composition comprises a viscosity of about 2.0 to about 3.5 mPas, and wherein the fluorocarbon has a boiling point of about 4 degrees Celsius to about 60 degrees Celsius. | 2013-04-18 |
20130096205 | AQUEOUS COMPOSITION TO BE CONTAINED IN CONTAINER - Provided is an aqueous composition contained in a container, maintaining an excellent water-evaporation-inhibiting effect even when an alkali metal salt or the like is contained in the aqueous composition, and having excellent long-term stability. The aqueous composition contained in a container includes the following components (A) to (D): (A) a polyoxyethylene alkyl or alkenyl ether having an alkyl or alkenyl group having 20 to 24 carbon atoms and an average molar number of ethylene oxide added of 1.5 to 4, (B) a water-soluble polymer, (C) a nonionic surfactant having an ethylene oxide group (but excluding component (A)), and (D) water. | 2013-04-18 |
20130096206 | POWDER TREATMENT AGENT COMPRISING SUGAR ALCOHOL-MODIFIED ORGANOPOLYSILOXANE - The present invention has an objective to provide a surface treatment agent which is safe with no generation of hydrogen, can be suitably used in a surface treatment of powder(s), exhibits good compatibility with other raw materials of cosmetics, and therefore, can improve a dispersing property and stability of powder(s) contained in a cosmetic, as well as provide a powder which has been subjected to a surface treatment with the aforementioned powder treatment agent, and a cosmetic raw material and a cosmetic which are produced by blending them, exhibit superior storage stability, have a superior outer appearance, and exhibit a superior sensation during use. A sugar alcohol-modified organopolysiloxane having a specified structure is used in the powder treatment. | 2013-04-18 |
20130096208 | COSMETIC PREPARATION HAVING A CONTENT OF ACYL ARGINATES - Cosmetic or dermatological emulsions having a content of one or more acyl arginates of formula (I), where R and R | 2013-04-18 |
20130096209 | Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste - The present invention provides edible compositions comprising a compound of the present invention, food products comprising such edible compositions and methods of preparing such food products. The present invention also provides methods of reducing the amount of NaCl in a food product, methods of reducing the sodium intake in a diet, and methods of reducing bitter taste in a food product. | 2013-04-18 |
20130096210 | METAL-ORGANIC FRAMEWORKS WITH EXCEPTIONALLY LARGE PORE APERATURES - The disclosure relates to metal organic frameworks or isoreticular metal organic frameworks, methods of production thereof, and methods of use thereof. | 2013-04-18 |
20130096211 | Food Compositions Comprising Tailored Oils - Methods and compositions for the production of food compositions, oils, fuels, oleochemicals, and other compounds in recombinant microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a lipase, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a keto acyl-ACP synthase enzyme, a fatty acyl-ACP thioesterase, a fatty acyl-CoA/aldehyde reductase, a fatty acyl-CoA reductase, a fatty aldehyde reductase, a fatty aldehyde decarbonylase, and/or an acyl carrier protein are useful in manufacturing food compositions, and transportation fuels such as renewable diesel, biodiesel, and renewable jet fuel, as well as oleochemicals such as functional fluids, surfactants, soaps and lubricants. | 2013-04-18 |
20130096212 | Method and a Kit to Predict Response to Antidepressant Treatment - The present invention relates to the method for predicting the pharmacoresponse of antidepressants in patients diagnosed with major depression and panic disorder. According to the invention, SNP (rs41271330) in the coding region of the BMP5 gene together with the markers in linkage disequilibrium with this SNP could be used as predictors of SSRI treatment efficacy. The knowledge obtained by using the method disclosed in present invention has potential to increase the efficacy of pharmacological treatment in patients with major depression and panic disorder. The invention also provides a kit for detecting individual who are likely to respond to antidepressant treatment. | 2013-04-18 |
20130096213 | PROCESS AND APPARATUS FOR CONVERTING GREENHOUSE GASES INTO SYNTHETIC FUELS - Embodiments of the present invention are directed to apparatus and methods for converting carbon dioxide and/or methane into higher alkanes and hydrogen gas in a single reaction chamber using a catalyst and microwave radiation. | 2013-04-18 |
20130096214 | COMPOSITE HAVING ION EXCHANGE FUNCTION AND PREPARATION METHOD AND USE THEREOF - A composite having ion exchange function, preparation method and use thereof are provided. The composite is formed by compounding ion exchange resin with fluorine-containing polymer porous membrane, wherein the nitrile groups in the ion exchange resin react with the nitrile groups grafted on the fluorine-contained polymer porous membrane to form triazine ring crosslinked structure. The composite has excellent mechanical property and gas impermeability, high ion exchange capacity and high electroconductivity. | 2013-04-18 |
20130096215 | Hydrophobic Onium Salt Addition to Fuel Cell Electrode Inks for Improved Manufacturability - An ink composition for forming fuel cell electrodes includes a solvent system, an ion-conducting polymer dispersed within the solvent system, a supported catalyst dispersed within the solvent system; and an onium compound having a hydrophobic hydrocarbon moiety. The onium compound is substantially soluble in the solvent system. | 2013-04-18 |
20130096216 | METHOD AND CHEMICAL COMPOSITION FOR RECLAIMING OF CURED ELASTOMER MATERIALS - Reclaiming cured elastomer material by mixing the cured elastomer as crumbs or chips with a devulcanization-aiding chemical composition, and devulcanizing the cured material by applying a shear-stress deformation to the mixture of the crumbs or chips with a devulcanization-aiding chemical while performing a mechanical disintegration of the cured elastomer into fine-ground crumbs under controllable temperature not exceeding about 90 degrees C., where the chemical composition includes a first agent promoting scission of sulfide bonds of free radicals formed under the shear-stress deformation, which is selected from amines and sulfides and their derivatives, a second agent providing the pre-set acidity during the process inhibiting recombination of sulfide bonds, which is selected from organic acids and their anhydrides, a third agent contributing to fast stabilization of the free radicals, which is selected from oxidants, and a fourth agent promoting redox reaction, which is selected from oxides of metals with variable valence. | 2013-04-18 |
20130096217 | METHOD FOR FABRICATING A CERAMIC MATERIAL - A method for fabricating a ceramic material includes impregnating a porous structure with a mixture that includes a preceramic polymer and a filler. The filler includes at least one free metal. The preceramic polymer material is then rigidized to form a green body. The green body is then thermally treated to convert the rigidized preceramic polymer material into a ceramic matrix located within pores of the porous structure. The same thermal treatment or a second, further thermal treatment is used to cause the at least one free metal to move to internal porosity defined by the ceramic matrix or pores of the porous structure. | 2013-04-18 |
20130096218 | HEAT TRANSFER COMPOSITIONS OF HYDROFLUOROCARBONS AND A HYDROFLUOROOLEFIN - The present invention relates to heat transfer compositions comprising 2,3,3,3-tetrafluoropropene, difluoromethane, pentafluoroethane, and 1,1,1,2-tetrafluoroethane for use in refrigeration, air-conditioning, heat pump systems, and other heat transfer applications. The inventive heat transfer compositions can possess reduced global warming potential while providing good capacity and performance. | 2013-04-18 |
20130096219 | REDUCING POLYMERIZATION-INDUCED SHRINKAGE STRESS BY REVERSIBLE ADDITION-FRAGMENTATION CHAIN TRANSFER - The invention provides methods of reducing shrinkage stress in cross-linked polymerized materials by combining an addition-fragmentation chain transfer additive with a resin system prior to polymerization. The methods of the invention can improve the performance of conventional resin systems by reducing the shrinkage stress without significantly degrading the mechanical properties of the polymerized material. The shrinkage stress in the crosslinked polymeric materials produced by the methods of the invention may be from 25% to 75% of that of a control material produced by polymerization of the resin system alone to the same conversion. | 2013-04-18 |
20130096220 | GRAFTED PHOTOINITIATORS - The invention provides a method for producing a polymeric photoinitiator, of the general formula I: Polymer-[CR2-CHR-Spacer(PI) | 2013-04-18 |
20130096221 | HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS - The invention provides a method for the manufacture of a gel, said method comprising the steps of: providing a matrix composition comprising a polymeric photoinitiator of the general formula (I): Polymer-[CR | 2013-04-18 |
20130096222 | Polyolefin-Based Crosslinked Compositions and Methods of Making Them - Provided is a method for providing a composition comprising at least one propylene-based polymer; at least one of multifunctional acrylates, multifunctional methacrylates, functionalized polybutadiene resins, functionalized cyanurate, and allyl isocyanurate; at least one of hindered phenols, phosphites, and hindered amines; and at least one photoinitiator for UV curing. The propylene-based polymer can include propylene derived units and one or more dienes, and have a triad tacticity of from 50% to 99% and a heat of fusion of less than 80 J/g. The composition can be extruded and crosslinked. The crosslinked composition is particularly useful for making films and fibers. | 2013-04-18 |
20130096223 | METHOD FOR CURING ADDITION CURABLE ORGANOPOLYSILOXANE COMPOSITION - A method for curing an addition curable organopolysiloxane composition is provided. This method uses a UV activatable platinum catalyst (complex), and this method has enabled consistent curing of the parts where UV exposure is impossible as well as consistent curing of a thick article. This method cures an addition curable organopolysiloxane composition comprising (A) an organopolysiloxane having at least 2 alkenyl groups bonded to silicon atoms per molecule, (B) an organohydrogenpolysiloxane having at least 2 hydrogen atoms bonded to silicon atoms per molecule, and (C) an effective amount of a photoactivatable platinum complex curing catalyst, and the method comprises the first step of exposing the composition to UV to increase catalytic activity of the component (C), and the second step of applying the composition obtained in the first step to a desired position and curing the composition. | 2013-04-18 |
20130096224 | POLYURETHANE BASED PHOTOINITIATORS - A photoinitiator of the general formula (I): (—(R | 2013-04-18 |
20130096225 | WHITE INKJET INK IMPROVED FOR DISPERSION STABILITY - An inkjet printing method includes the steps of a) providing a white inkjet ink and at least one colour inkjet ink to an inkjet printer; and b) jetting the white inkjet ink at a higher temperature than the colour inkjet ink onto an ink-receiver. The difference in jetting temperature between the white inkjet ink and the colour inkjet ink is at least 5° C. Inkjet ink sets and inkjet printers are also disclosed. | 2013-04-18 |
20130096226 | DENTAL COMPOSITE RESTORATIVE MATERIAL - There is provided a dental composite restorative material that has an excellent opalescent effect, no paste stickiness, small polymerization shrinkage during curing and is suitable for the restoration of the incisal edge of a tooth. This dental composite restorative material comprises: (A) a polymerizable monomer, (B) a spherical silica-based particle [I] having an average particle diameter in the range of from 0.1 to 0.5 μm and a standard deviation of particle diameter distribution within 1.30, preferably a silica-titanium group oxide-composite oxide particle, (C) an organic-inorganic composite filler prepared by dispersing the above-described silica-based particle [I] in an organic resin matrix, and (D) a polymerization initiator. | 2013-04-18 |
20130096227 | FORMULATIONS CONTAINING A PLASTICIZER AND FUNGICIDE AND ARTICLES MADE THEREFROM - The present invention relates to formulations which comprise a plasticizer and articles made therefrom and/or coated therewith. More specifically the formulation comprises a plasticizer and a fungicidally effective amount of Fludioxonil and/or Difenoconazole. The formulations have particular application in the manufacture of plasticized articles and articles which have been coated with a fungicide containing plastisol. | 2013-04-18 |
20130096228 | FRICTION MATERIAL - In accordance with the present invention, there is provided a friction material. The friction material of the present invention includes a fibrous material, a binder, and a friction modifier. The friction modifier contains an artificial graphite and an inorganic filler. The artificial graphite has an average particle diameter of 1,000 to 3,000 μm. The inorganic filler has a plurality of convex parts. | 2013-04-18 |
20130096229 | PLASTISOLS CONTAINING GLYCEROL ESTERS AS PLASTICIZERS - Plastisols and organosols are provided that include plasticizers that include mono-, di- and triesters of glycerol. The plasticizers are good solvators for polyvinyl chloride and impart low plastisol and organosol viscosities. | 2013-04-18 |
20130096230 | METHOD FOR OBTAINING A RUBBER COMPOSITION INCLUDING A THERMOPLASTIC FILLER - A process for the preparation of a rubber composition for the manufacture of tyres is presented. The composition is based on one or more diene elastomers, one or more reinforcing fillers, and a crosslinking system. The composition includes particles of one or more thermoplastic materials chosen from amorphous thermoplastic materials and semicrystalline thermoplastic materials, with the glass transition temperature of the amorphous thermoplastic material or materials and the melting point of the semicrystalline thermoplastic material or materials varying from 80° C. to 300° C. The particles exhibit a volume-average diameter of less than or equal to 200 μm. | 2013-04-18 |
20130096231 | MASTERBATCH COMPOSITION - The instant invention provides a masterbatch composition, method of producing the same, polymeric compositions suitable for films, and films made therefrom. The masterbatch composition according to the present invention comprises: (a) from 70 to 90 percent by weight of a filler comprising calcium carbonate; and (b) from 10 to 30 percent by weight of a propylene/alpha-olefin copolymer composition, wherein said propylene/alpha-olefin copolymer composition has a crystallinity in the range of from 1 percent by weight to 30 percent by weight, a heat of fusion in the range of from 2 Joules/gram to 50 Joules/gram, and a DSC melting point in the range of 25° C. to 110° C. | 2013-04-18 |
20130096232 | CURABLE EPOXY RESIN COMPOSITIONS AND COMPOSITES MADE THEREFROM - A diluent-free curable epoxy resin composition for preparing a composite comprising: (A) at least one epoxy resin composition comprising a blend of: (A1) at least one epoxy resin, and (A2) at least one divinylarene dioxide; and (B) at least one hardener composition; and (C) at least one reinforcement materials; wherein the viscosity of the curable composition is the range of from about 0.15 Pa-s to about 1.5 Pa-s; and wherein the curable composition is adapted for providing a cured composite product made from the curable composition such that the composition being cured provides a cured composite product having an increased Tg of greater than about 5° C. as compared to a curable composition having a reactive diluent. | 2013-04-18 |
20130096233 | EPOXY RESIN COMPOSITION FOR PREPREG, PREPREG, AND MULTILAYER PRINTED CIRCUIT BOARD - The problem to be solved by the invention is to provide an epoxy resin composition for a prepreg, which is used in the manufacture of a printed circuit board containing a multilayer printed circuit board, wherein the epoxy resin composition for a prepreg is characterized by containing as essential components, a phosphorus compound that has 1.8 or more and less than 3 on average of a phenolic hydroxyl group that is reactive to an epoxy resin in the molecule, and that has 0.8 or more on average of a phosphorus element; a bifunctional epoxy resin that has 1.8 or more and less than 2.6 on average of epoxy groups in the molecule; a multi-functional epoxy resin that contains 2.8 or more on average of epoxy groups in one molecule; a hardening agent; an inorganic filler; and a molybdenum compound, wherein the epoxy resin composition for a prepreg is obtained by blending a pre-reacted epoxy resin, which is obtained by reacting at least the phosphorus compound with the bifunctional epoxy resin and the multi-functional epoxy resin, or the bifunctional epoxy resin only in advance, the bifunctional epoxy resin or the multi-functional epoxy resin, the hardening agent, the inorganic filler, and the molybdenum compound, which is excellent in flame retardance, heat resistance, thermal stiffness, and excellent in hole position accuracy without the production of a harmful substance at the time of combustion, a prepreg using the epoxy resin composition for a prepreg, and a multilayer printed circuit board using the prepreg. | 2013-04-18 |
20130096234 | COLOR INDICATING EPOXY RESINS AND METHODS THEREOF - Described herein is an epoxy composition comprising: a first component comprising an amine-based curing agent and a first dye, having a first color; and a second component comprising a curable epoxy resin and a second dye, having a second color. Also described herein is a shelf-life-indicating composition comprising: an amine-based curing agent; and a dye selected from (i) a cationic triarylmethane dye, wherein the cationic triarylmethane dye reversibly reacts with a primary amine; (ii) a halochromic dye having a color transition range between 7-12 when measured in an aqueous solution; or (iii) combinations thereof. | 2013-04-18 |
20130096235 | Functionalized Particles and Use Thereof - A method of making a powder coating composition includes obtaining functionalized particles by reacting inorganic particles with alkoxysilanes having the general structural formula (I) R | 2013-04-18 |
20130096236 | PLANT MATERIAL COMPOSITIONS AND METHOD FOR PREPARING SAME - The present invention relates to a novel thermoplastic composition, characterized in that it contains: a) 15% to 60% of at least one starchy material; b) 10% to 30% of at least one starchy material plasticizer; c) 15% to 70% of at least one polyolefin; and d) 10% to 40% of at least one plant material selected among plant fibers and plant fillers. The invention also relates to a thermoplastic composition preparation method that includes the following steps: (i) selecting at least one composition (a) containing at least one starchy material, one plasticizer of said starchy material, and one polyolefin; (ii) selecting at least one plant material (b) selected among plant fibers and plant fillers, said plant material being formed of particles, the dimensions of which are between 0.5 and 5000 micrometers; and (iii) mixing the composition (a) and the plant material (b) so as to obtain the thermoplastic composition according to the invention. | 2013-04-18 |
20130096237 | COMPOSITE MATERIAL MADE OF A MATERIAL CONTAINING CELLULOSE WITH PMMA AS A PLASTIC MATRIX USING DIFFERENT COUPLING COMPONENTS - The invention relates to novel composite materials with improved mechanical properties and improved weathering resistance, said composite materials being made of at least one material containing cellulose, preferably wood, and at least one plastic, and to a method for producing said composite materials and for using same. | 2013-04-18 |
20130096238 | RENEWABLE AND COST-EFFECTIVE FILLERS FOR POLYMERIC MATERIALS - Polymer composites are provided, and more particularly, polymer composites of ground date pits disposed in a polymer matrix. The composites can be formed by a process of preparing reinforced polymer composites having a fibril melt fracture surface, including blending a mixture of date pit particulate with a thermoplastic polymer; melting the mixture; and forcing the melt through a die to produce the polymer composite having a fibril containing surface. | 2013-04-18 |
20130096239 | STARCH-BASED COMPOSITIONS FOR LATEX REPLACEMENT - A method for producing starch-based compositions, and the composition produced therewith, for use as latex substitutes for full or partial latex replacement in applications such as carpet backing. | 2013-04-18 |
20130096240 | System and Method for Pre-Treatment of Rubber-Modified Asphalt Cement, and Emulsions Thereof - This invention encompasses asphalt cement emulsions, as well as methods for preparing a pre-treated rubber-modified asphalt cement emulsions and methods for coating industrial surfaces using asphalt cement emulsions. | 2013-04-18 |
20130096241 | FUNCTIONALIZED NANOPARTICLES - Functionalized nanoparticles, which are obtainable by combining in a first step a functionalized dyestuff, a silicon-based spacer and a catalyst, and in a second step reacting the product obtained in the first step with a co-reactive organic silicon, aluminum, zirconium or titanium compound. Optionally, the thus obtained functionalized nanoparticles can be combined or encapsulated with a polymer. The functionalized nanoparticles are useful as colorants and fluorescents in plastics, paints, inks, electronic materials, cosmetic articles, and the like. | 2013-04-18 |
20130096242 | GLUE COMPOSITION COMPRISING THE SOLVENT N - ACETYLMORPHOLINE - The present disclosure relates to glues comprising a solution of at least one water-insoluble synthetic organic polymer selected from the group consisting of PVC and ABS, said glue comprising the solvent N-Acetylmorpholine. The subject matter further relates to use of the glue for joining surfaces of articles made from material comprising water-insoluble synthetic organic polymers selected from the group comprising PVC and ABS and to use of N-Acetylmorpholine in the manufacturing of glue comprising at least one water-insoluble synthetic organic polymer selected from the group consisting of PVC and ABS. | 2013-04-18 |
20130096243 | RESIN COMPOSITION AND RESIN MOLDED ARTICLE - A resin composition contains (A) a polylactic acid, (B) a polyhydroxyalkanoate, (C) an ammonium polyphosphate, and (D) a phenol-modified epoxy compound. With respect to the total amount of the resin composition, the polylactic acid (A) and the polyhydroxyalkanoate (B) are contained from about 60% by mass to about 95% by mass; the ammonium polyphosphate (C) is contained from about 4% by mass to about 35% by mass; the phenol-modified epoxy compound (D) is contained from about 1% by mass to about 5% by mass; the polylactic acid (A) is contained from about 40% by mass to about 90% by mass; the polyhydroxyalkanoate (B) is contained from about 5% by mass to about 55% by mass; and the amount ratio of the polylactic acid (A) to the polyhydroxyalkanoate (B) is from about 0.7 to about 18. | 2013-04-18 |
20130096244 | WATER-BASED LIQUID COLOR CONTAINING THERMOSTABLE DISPERSION ADDITIVES FOR THE COLORING POLY(METH)ACRYLATES - The invention relates to a method for coloring thermoplastic molding compounds, preferably a polymethyl(meth)acrylate molding compound, using novel aqueous colorant preparations. The invention further relates to a novel water-based colorant preparation. | 2013-04-18 |
20130096245 | Single-walled Metal Oxide and Metal Sulphide Nanotubes/Polymer Composites - The present invention discloses a nanocomposite material having single-walled aluminosilicate nanotube in polymer, a membrane comprising such nanocomposite material, and the method of making the nanocomposite material, in which the composite material has high volume fraction of well-dispersed nanotubes. A gel-phased single-walled aluminosilicate nanotube is first prepared and then mixed with a polymer matrix to yield the composite material. | 2013-04-18 |
20130096246 | Composite Material and Related Methods - A composition having a composite material having a polymer with about 1% to about 3% by weight thin-graphite materials dispersed therein; the thin-graphite materials having diameters less than or equal to 2 microns and a surface area greater than or equal to about 300 m | 2013-04-18 |
20130096247 | POLYOLEFIN-BASED RESIN COMPOSITION - Provided is a polyolefin-based resin composition capable of obtaining a molded product having a high modulus of elongation and a low coefficient of linear expansion. The polyolefin-based resin composition includes a polyolefin-based resin containing either one or both of an acid-modified polyolefin-based resin and a polyolefin-based resin with a hydroxyl group, and flaked graphite. The flaked graphite is uniformly dispersed in the polyolefin-based resin. As a result, a molded product formed by using the polyolefin-based resin composition has excellent mechanical strength such as a high modulus of elongation, a low coefficient of linear expansion, and high dimensional stability, and can be used for various applications such as a material that is suitable for use as the exterior panels of automobiles or a steel sheet replacement material. | 2013-04-18 |