15th week of 2012 patent applcation highlights part 42 |
Patent application number | Title | Published |
20120089006 | ELECTROMAGNETIC INTERFERENCE SUPPRESSION DEVICE AND MRI APPARATUS USING THE SAME - An electromagnetic interference suppression device and an MRI apparatus using such a device are disclosed. The MRI apparatus may include a main magnet, a gradient coil, an RF coil placed in a shielding chamber, a control system, and an electromagnetic interference suppression device. | 2012-04-12 |
20120089007 | Dual Imaging Acquisition Using Common Time-Base Frequency - Timing in a medical imaging system. The system comprises a magnetic resonance imaging (MRI) subsystem and a non-MRI subsystem. Operation of the non-MRI subsystem involves a timing signal within a radio frequency (RF) cabin of the MRI subsystem. Basing each non-MRI subsystem timing signal on a time base common between the MRI subsystem and the non-MRI subsystem. The non-MRI subsystem can be a medical imaging subsystem. The non-MRI medical imaging subsystem can be a positron emission tomography (PET) subsystem. Each non-MRI subsystem timing signal that based on the common time base can be created using the same model of equipment used for creating timing signals in the MRI subsystem. At least one stage of the non-MRI subsystem timing signal based on the common time base can be created using the same equipment used for creating timing signals in the MRI subsystem. | 2012-04-12 |
20120089008 | SYSTEM AND METHOD FOR PASSIVE MEDICAL DEVICE NAVIGATION UNDER REAL-TIME MRI GUIDANCE - A method for tracking a needle along a path under real-time magnetic resonance imaging (MRI) guidance includes extracting a candidate needle artifact region from a plurality of incoming MR images of a needle inside biological tissue, determining an initial needle direction vector from the candidate needle artifact region in each of the plurality of incoming needle images, determining an initial needle base point from an intersection of the needle direction vector with a first incoming needle image, and an initial needle tip point from an intersection of the needle direction vector with a last incoming needle image, and tracking said needle by minimizing a cost function of the initial base point and initial direction vector to calculate an updated base point and updated direction vector. The updated base point and direction vector are used to visualize the advance of the needle along the path through the biological tissue. | 2012-04-12 |
20120089009 | METHODS AND APPARATUS TO DELIVER NANOPARTICLES TO TISSUE USINGELECTRONANOTHERAPY - Methods, systems, and apparatus are disclosed to provide delivery of nanoparticles to tissue using electro-nanotherapy or nanoablation. | 2012-04-12 |
20120089010 | HYPERPOLARIZED CONTRAST AGENT DISPENSER FOR MAGNETIC RESONANCE IMAING - A dispenser ( | 2012-04-12 |
20120089011 | METHOD AND APPARATUS FOR SCANNING CONTROL AND DISPLAYING IMAGES IN A MAGNETIC RESONANCE SCANNING CHAMBER - A method and apparatus for scanning control and displaying an image in a magnetic resonance scanning chamber are disclosed. An apparatus includes a magnetic resonance imaging system, a scanning chamber computer, an operating chamber computer, and a communication connection device; the scanning chamber computer and the magnet are disposed in the scanning chamber together; the operating chamber computer is disposed in the operating chamber; the scanning chamber computer and the operating chamber computer are connected via the communication connection device. | 2012-04-12 |
20120089012 | METHOD AND APPARATUS FOR NAVIGATING A CUTTING TOOL DURING ORTHOPEDIC SURGERY USING A LOCALIZATION SYSTEM - The invention provides methods and apparatus for accurately cutting bones with a surgical cutting device, such as a sagittal saw, using a surgical navigation system without use of a complex cutting jig. A surgical navigation system is used to navigate a guide tube to be used to drill a k-wire into the bone. The k-wire will act as a guide to control at least one degree of freedom of a saw blade for making a cut in the bone. In an exemplary high tibial osteotomy procedure, in which two intersecting planar cuts must be made in the tibia in order to remove a wedge of bone, a surgical navigation marker is mounted on the guide tube. The surgeon uses the surgical navigation system to navigate the guide tube to the desired varus-valgus angle and height of the first cut and then drills a k-wire into the tibia at that varus-valgus angle using the guide tube. The process is repeated for the second cut. The surgeon then uses the two k-wires as guides for controlling the varus-valgus angle of a sagittal saw for the two planar cuts. The surgeon rests the saw blade flat on the respective k-wire to define the varus-valgus angle of the cut. The saw itself also is navigated, with the surgical navigation system providing a display showing the surgeon at least (1) the varus-valgus angle, (2) the cut depth, and (3) the anterior-posterior slope. The anterior-posterior slope and the depth of the cut is controlled freehand by the surgeon. | 2012-04-12 |
20120089013 | EM TRACKING SYSTEMS FOR USE WITH ULTRASOUND AND OTHER IMAGING MODALITIES - An EMT system for use in ultrasound and other imaging modality guided medical procedures. The system includes a tool set of various components to which EM sensors can be releasably secured. Thus, the sensors can be reused, notwithstanding the disposal of other components of the tool set. Various components of the tool set include keying elements to facilitate their registration to the anatomy of the patient undergoing the procedure via the EM sensors. | 2012-04-12 |
20120089014 | METHOD AND APPARATUS FOR TRACKING IN A MEDICAL PROCEDURE - A tracking system for a target anatomy of a patient can include a medical device having a body ( | 2012-04-12 |
20120089015 | REGIONAL RECONSTRUCTION AND QUANTITATIVE ASSESSMENT IN LIST MODE PET IMAGING - A method for reconstructing list mode data comprises: reconstructing all list mode data of a list mode data set ( | 2012-04-12 |
20120089016 | DIAGNOSIS ASSISTING APPARATUS, DIAGNOSIS ASSISTING PROGRAM, AND DIAGNOSIS ASSISTING METHOD - A diagnosis assisting apparatus, method, and program include calculating a first index value representing a direction and magnitude of motion of each portion of the heart for a three-dimensional anatomical image at a given phase of a three-dimensional anatomical image group representing a heart at each phase with respect to a further phase, calculating a second index value that serves as a diagnostic indicator of each portion of the heart from the three-dimensional anatomical image at the given phase or the three-dimensional anatomical image group, generating a two-dimensional image of the entire heart in which the second index value of each portion of the heart is disposed in a planar fashion, and displaying a mark representing the first index value superimposed on the generated two-dimensional image in a manner that allows the direction of motion of the first index value to be visually recognized. | 2012-04-12 |
20120089017 | LIGANDS TO RADIATION-INDUCED MOLECULES - A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. In some embodiments, the method includes the steps of (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are targeting ligands that bind an irradiated tumor and therapeutic and diagnostic methods that employ the disclosed targeting ligands. | 2012-04-12 |
20120089018 | FLUID CONNECTION ASSEMBLY WITH LOCKING MECHANISM - In general, this disclosure relates to techniques for implementation and use of a fluid connection assembly, having a locking mechanism, which may be connected to a medical fluid injection device. An example fluid connection assembly includes at least one fluid connector, a mating mechanism coupled to the at least one fluid connector and configured to connect the at least one fluid connector to a medical fluid injection device, and a locking mechanism coupled to the mating mechanism and movable into a locked position or an unlocked position. In this example, the fluid connection assembly becomes affirmatively coupled with the medical fluid injection device when the locking mechanism is in the locked position, and the fluid connection assembly becomes removably decoupled from the medical fluid injection device when the locking mechanism is in the unlocked position. | 2012-04-12 |
20120089019 | Solving for Shear Wave Information in Medical Ultrasound Imaging - A shear wave velocity solution is provided for medical ultrasound imaging. Rather than determining shear wave information for each location based on distance from the origin of the shear wave and time to peak displacement for the location, displacement profiles resulting from different combinations of origin and detection locations are correlated. Shear information is detected using displacements from a diverse spatial combination of transmission locations and detection locations. The correlation combination is used in a same function for simultaneously solving for the delays for multiple lateral locations. Spatial diversity and layered correlation may provide for more accurate shear wave estimation. | 2012-04-12 |
20120089020 | BLOOD VESSEL FUNCTION INSPECTING APPARATUS - A blood vessel function inspecting apparatus including a first blood state index value calculating portion that obtains estimated hematocrit values at a plurality of points predetermined within a blood vessel, on the basis of values of a blood viscosity and values of a shear rate at said plurality of points, which are respectively extracted from a viscosity distribution and a shear rate distribution, and according to reference relationships between a hematocrit value and the blood viscosity, which reference relationships respectively correspond predetermined different values of the shear rate; and a second blood state index value calculating portion that calculates, as said blood state index value, a value relating to an amount of difference of the estimated hematocrit values at said plurality of points with respect to each other, which amount is minimized by transforming said reference relationships at the same ratio for all of the values of the shear rate. | 2012-04-12 |
20120089021 | Method and system for three-dimensional (3D) imaging of biological structures - An ultrasonic scanning apparatus that includes a unique ultrasonic array to transmit ultrasonic energy to a biological structure, such as an eye. The ultrasonic array provides specific three-dimensional (3-D) information relating to the eye and precise volumetric information relating to structures associated therewith, such as a tumor, prior, during and/or after treatment. The ultrasonic array can also be combined with a therapeutic ultrasonic unit for real-time 3-D observation of a structure and the focal point of the transmitted therapeutic beam(s) on a monitor during the treatment of a structure, e.g., treatment of a lesion. | 2012-04-12 |
20120089022 | DELIVERY CATHETER WITH FORWARD-LOOKING ULTRASOUNG IMAGING - A catheter based medical device is provided for a percutaneous surgical procedure that provides forward-looking visualization and delivery of a medical device. The catheter includes a carriage at its distal end and an ultrasonic transducer is supported by the carriage. A conduit that has its proximal end disposed within the catheter and the conduit passes through the sidewall of the catheter proximate to the distal end of the catheter so that the distal end of the conduit is disposed on an exterior of the sidewall of the catheter. A medical device is deliverable through the lumen of the conduit and the ultrasonic transducer provides visualization of the medical device distally of the transducer. | 2012-04-12 |
20120089023 | PARAMETER-SENSING ENDOTRACHEAL TUBE - A sensor-equipped endotracheal tube has a flexible body surrounding an airway lumen and includes sensors for monitoring physiological parameters such as CO | 2012-04-12 |
20120089024 | METHOD OF PROVIDING THREE DIMENSIONAL COLOR DOPPLER IMAGE AND ULTRASOUND SYSTEM FOR IMPLEMENTING THE SAME - There is disclosed an embodiment for providing a three dimensional color Doppler image. An ultrasound data acquisition unit may transmit and receive ultrasound signals to and from a target object to output ultrasound data. A processor may form Doppler signals including power information of the target object and at least one of direction information and velocity information of the target object by using the ultrasound data. The processor may further form a three dimensional Doppler mode image representing the power information and at least one of the direction information and the velocity information by using the Doppler signals. | 2012-04-12 |
20120089025 | ULTRASOUND DIAGNOSTIC APPARATUS AND ULTRASOUND DIAGNOSTIC METHOD - An ultrasound diagnostic apparatus which observes an inside of a body of a subject based on ultrasound waves reflected from the inside of the body and obtained using an ultrasound probe, includes: a B-mode image generation unit which generates a B-mode image, based on the reflected ultrasound waves; a blood flow image generation unit which generates, based on the reflected ultrasound waves, a blood flow image representing a region of the body in which blood flows; a lumen contour extraction unit which extracts a lumen contour of a blood vessel, based on the blood flow image; a provisional adventitia contour setting unit which sets a provisional adventitia contour containing the lumen contour; and an adventitia contour extraction unit which extracts an adventitia contour of the blood vessel, using the B-mode image, and using the provisional adventitia contour as a first initial contour. | 2012-04-12 |
20120089026 | BREAST ULTRASOUND SCANNING TEMPLATE - Apparatus and related methods for facilitating volumetric ultrasonic scanning of a breast are described. In one preferred embodiment, a generally cone-shaped radial scanning template having a vertex and a wide opening angle is provided, the radial scanning template having a slot-like opening extending outward from the vertex through which an ultrasound transducer scans the breast as the radial scanning template is rotated. In another preferred embodiment, a flexible membrane for compressing a skin surface of the breast is provided, the flexible membrane being mounted on a mechanical assembly such as a roller assembly to form a slot-like opening through which an ultrasound transducer directly contacts the skin surface, the flexible membrane rising and falling relative to the skin surface but not moving laterally as the slot-like opening and ultrasound transducer move laterally across the compressed breast, whereby stabilization of the breast and direct transducer-skin contact are concurrently achieved. | 2012-04-12 |
20120089027 | Method and apparatus for ultrasonic detection and imaging of hemodynamic information, particularly venous blood flow information - A method for ultrasonic detection and imaging of hemodynamic information includes the steps of transmitting ultrasonic pulses into a body, which are generated by an array of electro-acoustic transducers arranged in a predetermined order and design; receiving reflected pulses with an array of receiving electro-acoustic transducers, which generate receive signals upon stimulation of the reflected pulses, the succession of pulses transmitted to or received from the body being focused along one or more scan lines; generating a Doppler frequency shift signal resulting from the reflection of pulses transmitted by a blood flow into a vessel intersected by the scan line, in a point and along the scan line, or along a direction of propagation of a pulse; determining the direction of blood flow velocity from the average frequency value of Doppler shift frequencies; and displaying the direction of blood flow velocity by graphical and/or chromatic representation differentiating opposite directions. | 2012-04-12 |
20120089028 | METHOD AND SYSTEM FOR INTRABODY IMAGING - A catheter that comprises a catheter configured for housing at least a portion of a catheter configured for insertion into a body lumen in proximity of a targeted anatomical site and having an imager at a distal end thereof and an adjustable chamber configured for covering the imager. The catheter is configured for introducing a wave conductive medium to the adjustable chamber to increase wave conductivity between said targeted anatomical site and the imager. | 2012-04-12 |
20120089029 | Connectorized Probe for Transesophageal Echocardiography - A connectorized ultrasound probe includes a distal section that is configured for insertion into a patient's body and a proximal section configured to interface the distal section with an ultrasound system. The distal section is easily attachable and detachable from the proximal section using at least one set of connectors. When connected, a user-operated actuator located on the proximal section controls the bending of the distal section, and the ultrasound system sends driving signals to and receives return signals from the ultrasound transducer via the proximal section. This arrangement is particularly advantageous for long term monitoring, because the disconnectability of the proximal section makes it possible to leave the distal section in place in the patient for longer periods of time without undue discomfort. In some preferred embodiments, the mechanical interface is made before the electrical interface when the distal section is connected to the proximal section. | 2012-04-12 |
20120089030 | SYSTEM AND METHOD FOR CHARACTERIZATION OF ORAL, SYSTEMIC AND MUCOSAL TISSUE UTILIZING RAMAN SPECTROSCOPY - A method and system for characterizing tissue includes a probe connected to a red LASER source and a Raman spectroscope. The probe includes at least excitation fiber and one or more emission fibers that connect the probe with the LASER source and the Raman spectroscope. The excitation fiber is connected to the red LASER source and terminates in the first end of the probe adjacent the tip of the probe. The emission fibers are connected to the Raman spectroscope and terminate in the first end of the probe adjacent the tip of the probe. In one embodiment, the excitation fiber extends through the central portion of the probe and one or more emission fibers are arranged around the excitation fiber. The tip of the probe is intended to come in contact with the tissue to be examined. The tip includes a central opening to allow red LASER radiation to project out of the end of the red excitation fiber on to the tissue and to permit Raman spectra to enter the emission fiber(s) and travel to the Raman spectroscope. The tip is constructed to have a predefined focal length to position the first end of the probe a predefined distance from the surface of the tissue being examined. The tip can be removable and tips having different focal lengths can be used to accommodate different types of tissues and examinations. A detector can convert the Raman spectra into signals and data for analysis by a computer system. The Raman spectra for tissue in a predefined location can be profiled such that the system can distinguish between healthy and diseased tissue. | 2012-04-12 |
20120089031 | SYSTEMS AND METHODS FOR SIDESSTREAM DARK FIELD IMAGING - The present application discloses systems and methods for the comprehensive monitoring of the microcirculation in order to assess the ultimate efficacy of the cardiovascular system in delivering adequate amounts of oxygen to the organ cells. In some cases, system embodiments may utilize reflectance avoidance by reflectance filtering, such as OPS imaging or Mainstream Dark Field imaging, or by Sidestream Dark Field imaging, which utilizes external direct light on the tip of the light guide to achieve reflectance avoidance whereby incident and reflected light do not travel down the same pathway. | 2012-04-12 |
20120089032 | METHOD AND SYSTEM FOR DISCRIMINATING AND MONITORING ATRIAL ARRHYTHMIA BASED ON CARDIOGENIC IMPEDANCE - A medical device is provided that comprises a lead assembly. The lead assembly includes at least one intra-cardiac (IC) electrode, an extra-cardiac (EC) electrode and a subcutaneous remote-cardiac (RC) electrode. The IC electrode is configured to be located within the heart. The EC electrode is configured to be positioned proximate to at least one of a superior vena cava (SVC) and a left ventricle (LV) of a heart. The RC electrode is configured to be located remote from the heart. An arrhythmia monitoring module is configured to analyze intra-cardiac electrogram (IEGM) signals from the at least one IC electrode to identify a potential atrial arrhythmia. An extra-cardiac impedance (ECI) module is configured to measure extra-cardiac impedance along an ECI vector between the EC and RC electrodes to obtain ECI measurements. The hemodynamic performance (HDP) assessment module is configured to determine a hemodynamic performance based on the ECI measurements. The arrhythmia monitoring module is configured to declare the potential atrial arrhythmia to be an atrial arrhythmia based on the hemodynamic performance determined from the ECI measurements. The medical device further provides the HDP assessment module that derives a current ECI waveform from current ECI measurements and compares the current ECI pattern with a prior ECI waveform that is derived from prior ECI measurements. | 2012-04-12 |
20120089033 | BIOINFORMATION DETECTING DEVICE - A bioinformation detecting device | 2012-04-12 |
20120089034 | NON-INVASIVE BLOOD PRESSURE MONITORING SYSTEMS - The present invention relates to the field of non- invasive blood pressure (NIBP) monitoring systems and particularly to a system that allows the identification of other components of the system via coding elements that are readable without the need for placement of this system components to the body of a patient. | 2012-04-12 |
20120089035 | IMPLANTABLE CARDIAC STIMULATOR, SYSTEM, DEVICE AND METHOD FOR MONITORING CARDIAC SYNCHRONY - In a system and method for monitoring cardiac synchrony in a human heart, a first sensor is positioned at a first cardiac wall location that is subject to movements related to longitudinal valve plane movements along the longitudinal axis of the heart, and measures the cardiac wall movements at the first cardiac wall location and a second sensor is positioned at a second cardiac wall location that is subject to movements related to longitudinal valve plane movements along the longitudinal axis of the heart, and measures the cardiac wall movements at the second cardiac wall location. A lead arrangement conducts respective output signals from the first and second sensors to processing circuitry that processes the first and second sensor output signals to produce a synchronization signal therefrom indicative of synchrony in the respective valve plane movements at the first and second cardiac wall locations. | 2012-04-12 |
20120089036 | Microcontrolled Electrocardiographic Monitoring Circuit With Feedback Control - A microcontrolled electrocardiographic monitoring circuit with feedback control is provided. An input signal path includes an electrode, a low pass filter, and an amplifier connected in-line. The electrode senses an input signal and the amplifier outputs a filtered amplified output signal. A microcontroller circuit includes an input codec, analog-to-digital converter, and feedback generation module. The analog-to-digital converter converts the filtered amplified output signal into a data stream of discrete digital values. The feedback module identifies a pairing of drive resistor settings matched to each discrete digital value, which are output as a digital feedback signal. The output signal path includes an electrode and a buffer connected in-line. A pair of drive resistors is connected in parallel to an input terminal of the buffer and to the output terminals of the feedback module. Each drive resistor is adjusted according to the digital feedback signal, and the electrode provides an output signal. | 2012-04-12 |
20120089037 | Ambulatory Electrocardiographic Monitor With Jumpered Sensing Electrode And Method Of Use - An ambulatory electrocardiographic (ECG) monitor with a jumpered sensing electrode and method of use is provided. Self-powered ECG sensing circuitry is fully enclosed in a housing that provides electrode connection receptacles on a bottom surface of the housing. A flexible and stretchable electrode mounting panel having an elongated shape is provided with a layer of skin adhesive on a skin contacting surface. Sensing electrodes are mounted on opposite ends of the mounting panel. Each sensing electrode includes an electrode pad facing the skin contacting surface and an oppositely-facing electrode connection plug. Each connection plug is removably and pivotably couplable into the connection receptacles. A jumper wire assembly includes a jumper connection plug electrically connected to a jumper connection receptacle. The jumper connection plug is removably and pivotably couplable into the connection receptacles and the jumper connection receptacle is removably and pivotably couplable into the connection plugs on the mounting panel. | 2012-04-12 |
20120089038 | Method and system for identifying cardiac arrhythmia driver sites - A method of identifying potential driver sites for cardiac arrhythmias includes acquiring a plurality of electrograms from a plurality of locations on at least a portion of a patient's heart. Using the acquired electrograms, at least one electrical activity map is generated. Desirable electrical activity maps include complex fractionated electrogram standard deviation and mean maps, dominant frequency maps, peak-to-peak voltage maps, and activation sequence maps. Using one or more of these maps (e.g., by analyzing one or more electrogram morphological characteristics represented by these maps), at least one potential driver site can be detected. | 2012-04-12 |
20120089039 | Microcontrolled Electrocardiographic Monitoring Circuit With Differential Voltage Encoding - A microcontrolled electrocardiographic monitoring circuit with differential voltage encoding is provided. An input signal path includes an electrode, a low pass filter, and an amplifier, which are each connected in-line. The electrode senses an input signal via a conductive surface and the amplifier outputs a filtered amplified output signal. A microcontroller circuit includes an input codec, an analog-to-digital converter, and an encoder. The analog-to-digital converter is connected to the input signal path through an output of the amplifier and converts the filtered amplified output signal into a data stream of discrete digital values. The encoder determines a differential voltage between a current discrete digital value and a prior discrete digital value in the data stream. Persistent memory is connected to the microcontroller circuit via a peripheral serial interface bus, wherein the differential voltages for each of the discrete digital values in the data stream are stored into the persistent memory. | 2012-04-12 |
20120089040 | ADAPTIVE SAMPLING OF HEART SOUNDS - A system and method to sense heart sounds with one or more implantable medical devices according to one or more signal processing parameters. The method alters one or more of the parameters as a function of one or more physiologic triggering events. The method then senses heart sounds with the one or more implantable medical devices according to at least the one or more altered signal processing parameters. | 2012-04-12 |
20120089041 | ULTRASOUND-OBSERVABLE, RESPIRATORY GAS-WARMING, PARAMETER-SENSING ENDOTRACHEAL TUBE - An ultrasound observable endotracheal tube, according to a specific embodiment of the present invention, has a flexible body surrounding an airway lumen and includes an ultrasound-reflecting element making the tube visible within the body using ultrasound. In another specific embodiment, an endotracheal tube includes a heating member used for warming inhaled respiratory gases. Another specific embodiment of an endotracheal tube includes a sensor for measuring pressure exerted between an inflation cuff and a patient's tracheal tissues for preventing injury from over/under cuff inflation. Yet another specific embodiment of an endotracheal tube includes a sensor for measuring a CO | 2012-04-12 |
20120089042 | DIAGNOSIS OF ASTHMA - An apparatus ( | 2012-04-12 |
20120089043 | INCENTIVE SPIROMETRY DEVICE HAVING AN EXTERNALLY DISPOSED CAPACITIVE SENSOR ASSEMBLY FOR PROMPTING PATIENT USE AND DETERMINING MEASUREMENTS OBTAINED FROM SUCH PATIENT USAGE - An apparatus used in the medical industry such as an Incentive Spirometer, in order to increase transpulmonary pressure and respiratory volumes, to improve inspiratory muscle performance and re-establish the normal pulmonary hyperinflation, through the employment of electronic technology, providing audible, simulated, verbal, human sounding words, that assist, guide and prompt, increasing patient usage. In one embodiment, the Incentive Spirometer uses a capacitive sensing circuit preferably mounted to the side of the apparatus's housing for sensing movement of the float within the tube wall and for obtaining a measurement or reading of the patient's performance with the Incentive Spirometer. | 2012-04-12 |
20120089044 | BIOLOGICAL SIGNAL DISPLAY APPARATUS - A biological signal display apparatus includes: a stimulation unit which performs stimulation on a living body; a measurement unit which measures an evoked response evoked by the stimulation; a calculator which calculates a feature amount of the evoked response; a display unit; and a display controller which, based on the feature amount calculated by the calculator, displays a bar-shaped image on the display unit, each time when the stimulation is performed, the bar-shaped image corresponding with the evoked response on the display unit. | 2012-04-12 |
20120089045 | MEASUREMENT SYSTEM FOR EVALUATING THE SWALLOWING PROCESS AND/OR FOR DETECTING ASPIRATION - The invention relates to the use of measurement system for evaluating a swallowing process, preferably a closure of the airway during the swallowing process and/or an aspiration. The measurement system can be used for supporting therapy in case of swallowing disorders and/or for diagnosing changes in swallowing sequence. | 2012-04-12 |
20120089046 | Methods for Measuring Cross-Sectional Areas in Luminal Organs - Methods for measuring cross-sectional areas in luminal organs. In at least one embodiment of a method for measuring a size parameter of a targeted treatment site of the present disclosure, the method comprises the steps of introducing an impedance device into a treatment site, the impedance device selected from the group consisting of an impedance catheter and an impedance wire; injecting a first solution of a first compound having a first conductivity into the treatment site; measuring a first conductance value at the treatment site using the impedance device, the first conductance value indicative of a bolus of the first solution, and calculating a size parameter of the treatment site based in part upon the first conductivity of the first solution, the first conductance | 2012-04-12 |
20120089047 | CRYOABLATION APPARATUSES, SYSTEMS, AND METHODS FOR RENAL NEUROMODULATION - Catheter apparatuses, systems, and methods for cryogenically modulating neural structures of the renal plexus by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a cryo-applicator to a renal artery via an intravascular path. Cryogenic renal neuromodulation may be achieved via application of cryogenic temperatures to modulate neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. | 2012-04-12 |
20120089048 | REDUCED-PAIN ALLERGY SKIN TEST DEVICE - An allergy skin test device is disclosed that causes less pain than commonly used devices that include multi-point sharp puncture heads. The allergy skin test device incorporates multiple dull pressure heads distributed amongst the sharp multi-point sharp puncture heads, each dull pressure head activating a neurological pain gate that reduces pain sensation typically caused by the neighboring multi-point head when it engages the skin. | 2012-04-12 |
20120089049 | HEAD TILT RESPONSE - The present invention relates to the estimation of the vertical in humans using an experimental design that incorporates virtual reality. Methods of measuring the perceived vertical in a subject using steady state and transient experiments are disclosed. The inventive methods are useful for diagnosis, as well as for follow up after patient rehabilitation. | 2012-04-12 |
20120089050 | PUNCTURE NEEDLE CARTRIDGE AND PUNCTURE DEVICE - A puncture needle cartridge | 2012-04-12 |
20120089051 | Blood Glucose Meter Having Integral Lancet Device And Test Strip Storage Vial For Single Handed Use And Methods For Using Same - A blood glucose meter having a test strip port and an adjustable lancet device disposed at the same end of the device body is disclosed. The device body further includes an enclosure at the proximal end of the device body which houses a test strip storage vial and which facilitates one-handed opening and closing of the vial to simplify access to test strips contained therein. The enclosure is further provided with a window which allows the reading of the lot numbers on the label of the test strip vial therein without necessitating removal of the vial. A data connector is also provided on the device body for communication access, such as to upload data from other devices or to download data to other devices. | 2012-04-12 |
20120089052 | Massaging device with multiple ultrasonic transducers - The present invention teaches an ultrasonic device for skin care massage, comprising one or more ultrasonic vibration transmission plates, each of which having a backside and a smooth surface for contacting human skin; and at least two different ultrasonic vibration transducers coupled to a backside of each of the ultrasonic vibration plates. Each of the ultrasonic vibration transducers generates an ultrasonic wave with a unique frequency between 20 kHz to 25 MHz. Each of the ultrasonic vibration transducers has a bottom surface paralleling to the smooth surface. A distance between the bottom surface of any of the ultrasonic vibration transducers to the smooth surface is approximately an integer times of the half wavelength of the ultrasonic wave generated by the ultrasonic vibration transducer. | 2012-04-12 |
20120089053 | METHOD OF APPLYING SHEAR STRESS - An ultrasonic horn for use with an ultrasonic surgical hand piece including a resonator comprises a contacting annulus having a plurality of angled lands. The lands are alternated around the annulus such that adjacent lands have opposite angles. As a result of the adjacent angled lands, a shear stress field is developed in contacted tissue due to the promotion of refracted longitudinal ultrasonic waves propagating in different directions at the interface to the coupled tissue. The shear stress field enhances the fragmentation and removal rate of fibrous, elastic, and tenacious tissue. The horn is hollow permitting suction to be applied to the tissue for controlling tissue contact with the lands. | 2012-04-12 |
20120089054 | WEARABLE CPR ASSIST TRAINING AND TESTING DEVICE - A wearable cardiopulmonary resuscitation assist device or system including: a wearable article to be worn by a cardiopulmonary resuscitation performer or a patient, for assisting administration of cardiopulmonary resuscitation by the performer; at least one sensor for measuring at least one parameter to assist in cardiopulmonary resuscitation; at least one feedback component for conveying feedback information based on the parameter to the performer for assisting the performer in performing cardiopulmonary resuscitation; and a processing unit, the processing unit being configured to receive the at least one parameter from the at least one sensor and to send information based on the parameter to the at least one feedback component. Also a method for training or improving cardiopulmonary resuscitation procedures using the device. | 2012-04-12 |
20120089055 | PATIENT TAPE FORCE PAD - A CPR device for aiding a user in the performance of chest compressions, which is adapted to be placed on the chest of a patient and has means for measuring the compression force applied. The device has an electrically conductive means ( | 2012-04-12 |
20120089057 | FREQUENCY THERAPY METHOD AND DELIVERY SYSTEM - In a therapy method, the oscillations/vibrations of a natural substance or plant are first measured. Environmental signals are canceled out to isolate only a useful signal. The useful signal is then amplified and stores in a sound file library containing a many such useful signals. An audio file is generated by mixing from one or more useful signal files from the sound file library and the audio file is then delivered to a subject. The delivery may be effected by direct sound playback, via the tympanic membrane or the skin of the user, or by exposing a carrier medium, such as water or cream or oil, to the mixed file and then applying the carrier medium to the subject. | 2012-04-12 |
20120089058 | EXERCISE GARMENT WITH LOCALIZED MASSAGE FEATURE - An exercise garment of elastic material is constructed with embedded rigid balls to provide a localized massage to the wearer during exercise. | 2012-04-12 |
20120089059 | APPARATUS, SYSTEMS, AND METHODS FOR AUGMENTING THE FLOW OF FLUID WITHIN BODY VESSELS - Apparatus, systems, and methods are sized and configured to effectively and efficiently augment the flow of fluid within body vessels, not only during conditions in which a patient is bedbound and immobile, but also in conditions when the individual is out of bed, and completely mobile and ambulatory. | 2012-04-12 |
20120089060 | APPARATUS, SYSTEMS, AND METHODS FOR AUGMENTING THE FLOW OF FLUID WITHIN BODY VESSELS - Apparatus, systems, and methods are sized and configured to effectively and efficiently augment the flow of fluid within body vessels, not only during conditions in which a patient is bedbound and immobile, but also in conditions when the individual is out of bed, and completely mobile and ambulatory. | 2012-04-12 |
20120089061 | APPARATUS, SYSTEMS, AND METHODS FOR AUGMENTING THE FLOW OF FLUID WITHIN BODY VESSELS - Apparatus, systems, and methods are sized and configured to effectively and efficiently augment the flow of fluid within body vessels, not only during conditions in which a patient is bedbound and immobile, but also in conditions when the individual is out of bed, and completely mobile and ambulatory. | 2012-04-12 |
20120089062 | APPARATUS, SYSTEMS, AND METHODS FOR AUGMENTING THE FLOW OF FLUID WITHIN BODY VESSELS - Apparatus, systems, and methods are sized and configured to effectively and efficiently augment the flow of fluid within body vessels, not only during conditions in which a patient is bedbound and immobile, but also in conditions when the individual is out of bed, and completely mobile and ambulatory. | 2012-04-12 |
20120089063 | APPARATUS, SYSTEMS, AND METHODS FOR AUGMENTING THE FLOW OF FLUID WITHIN BODY VESSELS - Apparatus, systems, and methods are sized and configured to effectively and efficiently augment the flow of fluid within body vessels, not only during conditions in which a patient is bedbound and immobile, but also in conditions when the individual is out of bed, and completely mobile and ambulatory. | 2012-04-12 |
20120089064 | Adjustable joint positioning device - A joint positioning device includes a restriction frame having a first straight section, a second straight section and two transverse section connected between the first and second straight sections. Each of the two transverse sections includes multiple connection plates which are pivotably connected to each other so that the two transverse sections can be adjustable to meet the desired curvatures of the patients. | 2012-04-12 |
20120089065 | Limb protection device - A joint-supporting device comprises tensile members extending from above the joint to below it, supplementing the tensile characteristics of the joint's tendons, ligaments, and other structure. The tension members extend between a proximal cuff above the joint to a distal cuff below it, and pass over a pad at the apex of the joint, redirecting the tension members. In order that the cuffs are supported in position so that the tension members can effectively support the joint, they are spaced away from the joint by compression members bearing on proximal and distal bolsters, in turn located positively by the boney structure of the joint. | 2012-04-12 |
20120089066 | DISPOSABLE STERILIZED CUPPING THERAPY APPARATUS - According to the present invention, a disposable sterilized cupping therapy apparatus comprises: an expansion part consisting of a foldable material, the inner volume of which corresponds to the inner volume of a cupping therapy device when expanded; and a resilient coupling part configured on a perimeter of the expansion part, wherein the expansion part is arranged within the cupping therapy device, the coupling part is resiliently pressed against and coupled to a bottom of the cupping therapy device, and the skin of a person receiving therapy that is within the cupping therapy device is sealed from the air outside the expansion part by means of the latter. | 2012-04-12 |
20120089067 | Article With Health-Benefit Agent Delivery System - A laminate having health-benefit agents therein is made by particle stabilization within the lamination process. By changing the substrate type (tissue, nonwoven, film) and/or the physical composition and/or attributes of the laminate layers, the release of the health-benefit agents can be controlled. The laminate, sometimes referred to as a liner, may be used in personal absorbent articles such as diapers, feminine pads, bandages, bed pads, and the like. | 2012-04-12 |
20120089068 | Silver-Embedded Foam Dressing - A dressing that comprises a contact layer for contacting a wound, with the contact layer including silicone; a foam-based hydrophilic middle layer that carries a metal-based antimicrobial agent; and a backing layer that prevents moisture within the dressing from escaping into the air through evaporation. Silicone in the contact layer interacts with the wound to minimize the appearance of scar tissue. Moisture, either applied beforehand or from the wound exudate, travels through the porous contact layer into the foam middle layer. There, the moisture acts to release metal ions from controlled-release mechanisms, such as zeolites containing the metal ions. The ions then travel within the moisture into the wound, where they act to kill bacteria and other infectious microorganisms and to prevent infections from gaining a foothold. Many embodiments, for the metal-based antimicrobial agent, use silver ions or a combination of silver ions and other metal ions. | 2012-04-12 |
20120089069 | Medical Dressing Containing Antimicrobial Agent And Related Methods Therefor - A medical dressing containing an antimicrobial agent is disclosed. The medical dressing comprises a layered fabric comprising an inner layer of substantially hydrophilic material, an outer layer of substantially hydrophobic material on both sides of the inner layer; and an antimicrobial agent. The antimicrobial agent may be releasably impregnated into the fabric, coated on said fabric or a combination thereof. The antimicrobial agent may be a biguanide, such as polyhexamethylene biguanide (PHMB). The fabric inner layer material may be substantially a cellulose fiber, preferably substantially rayon, and the fabric outer layer material may be substantially polyester, e.g., a combination of textile matrix grade polyester fiber and amorphous binder grade polyester fiber. The fabric is preferably treated with an aqueous solution of surfactant and PHMB to have about 1500-3500 ppm of extractable PHMB. | 2012-04-12 |
20120089070 | Catheter Assembly Including Triple Lumen Tip - A catheter assembly for use in accessing a vasculature of a patient during renal replacement or other therapies is disclosed. In one embodiment, the catheter assembly includes a catheter body that defines first and second lumens. The catheter body defines a distal tip region that includes a venous lateral opening that is in fluid communication with the first lumen and an arterial lateral opening that is in fluid communication with the second lumen. | 2012-04-12 |
20120089071 | IMPLANT DEVICE, TOOL, AND METHODS RELATING TO TREATMENT OF PARANASAL SINUSES - An implant device is configured to be implanted in a fistula to fluidly connect the lacrimal apparatus and a paranasal sinus. A surgical tool has an implant the implant device mounted on a carrier. Various methods involve a fistula between the lacrimal apparatus and a paranasal sinus. A kit includes an entry device for use to form a fistula and an implant tool for use to implant an implant device following formation of a fistula. | 2012-04-12 |
20120089072 | SUBCONJUNCTIVAL CONFORMER DEVICE AND USES THEREOF - The present invention provides a device for use in an eye with elevated intraocular pressure or glaucoma, the device comprising a subconjunctival conformer shaped to conform to the eye wall and a fluid director that directs or facilitates the flow of intraocular fluid out of the eye and into the subconjunctival or retrobulbar space. The present invention also provides a method of lowering intraocular pressure using the device of the present invention. | 2012-04-12 |
20120089073 | GLAUCOMA DRAINAGE DEVICE AND USES THEREOF - In one aspect, the present invention provides an implant device for use in an eye with elevated intraocular pressure or glaucoma. In another aspect, the present invention provides a method for lowering intraocular pressure and/or treating a condition associated with elevated intraocular pressure using the implant device of the present invention. | 2012-04-12 |
20120089074 | TAMPON - There is provided a tampon including an absorbent body that absorbs liquid. The absorbent body is characterized in that it includes on its outer surface a colored portion that is colored with a colorant and a non-colored portion that is not colored. | 2012-04-12 |
20120089075 | FIBROUS SHEET THAT DISINTEGRATES IN WATER, PROCESS FOR MANUFACTURING SAID FIBROUS SHEET, CORE CONSISTING OF STRIPS OF SAID FIBROUS SHEET - A fibrous sheet having a basis weight of between 20 and 1000 g/m2 that disintegrates in water, has 10% to 70% starch on the basis of the total weight of the dry fibrous sheet. The disintegration time in water, measured in accordance with standard NF Q34-020 applied to a specimen of the sheet of 9×8 cm | 2012-04-12 |
20120089076 | METHOD FOR TREATING INFLAMMATION - A method for treating IL-20 induced inflammation. An antagonist to IL-20 is administered to treat inflammation and associated diseases. The antagonist can be an antibody that binds to IL-20 or its receptor or a soluble receptor that binds to IL-20. Examples of such diseases are adult respiratory disease, psoriasis, eczema, contact dermatitis, atopic dermatitis, septic shock, multiple organ failure, inflammatory lung injury, bacterial pneumonia, inflammatory bowel disease, rheumatoid arthritis, asthma, ulcerative colitis and Crohn's disease. | 2012-04-12 |
20120089077 | OCULAR IONTOPHORESIS DEVICE - The invention relates to a device of ocular iontophoresis for delivering active substances, comprising a reservoir having an outer wall and a hollow body at least partly delimited by the outer wall, wherein the hollow body is capable of receiving an electrical conductive medium and active substances contained in the medium and has an outlet defining a surface, so-called “application surface”, intended to received a determine part of an eyeball surface, the application surface being at least partly limited by an outer line concave towards the optical axis of the eyeball, wherein the outer wall extends from the outer line with a global outwardly with respect to the said optical axis. | 2012-04-12 |
20120089078 | METHODS AND SYSTEMS FOR TOXIN DELIVERY TO THE NASAL CAVITY - Methods and systems for delivering toxin and toxin fragments to a patient's nasal cavity provide for both release of the toxin and delivery of energy which selectively porates target cells to enhance uptake of the toxin. The use of energy-mediated delivery is particularly advantageous with light chain fragment toxins which lack cell binding capacity. | 2012-04-12 |
20120089079 | Ultrasonic device with integrated specimen dispenser - This application teaches a novel ultrasonic skin care device with a built-in specimen containment and a dispensing mechanism to enable easy application of the specimen for hygiene operation of the device for skin beautification purpose. The device provides portability for usage anywhere and anytime and provides a flexibility of multi-purpose skin care treatment with a unique design of multiple specimen containment structures. | 2012-04-12 |
20120089080 | TISSUE REMOVAL DEVICES, SYSTEMS AND METHODS - A tissue removal device includes a cannula that can aspirate tissue under a vacuum applied in the cannula, and a hermetically sealed fluid regulator in fluid communication with the cannula that generates vacuum pulses according to a controllable pulse rate and flow rate. The tissue removal device may also have a vacuum conduit having two or more conduit sections where the inner diameter of an upstream conduit section is smaller than the inner diameter of a succeeding conduit section. A device is also provided for applying an elastic membrane to an open end of the cannula to allow a user to remove any remaining cortical material after cataract material has first been removed from the eye by vacuum pressure applied in the cannula. | 2012-04-12 |
20120089081 | Piezoelectric element driver - The invention teaches a palm-held massage device which includes a driver that drives one or more massage elements which provides massage vibrations in one or more ultrasonic and subsonic frequencies, a controller that provides commands to the driver, a signal generator that provides frequency references to the driver, a power supply coupled to a contactless charger, and a specimen dispensing system. | 2012-04-12 |
20120089082 | SHEATH FOR USE WITH AN ULTRASOUND ELEMENT - An apparatus for delivering ultrasound energy and a drug solution to a treatment site in a vessel is disclosed. The apparatus includes an elongate, hollow sheath having a distal opening and an energy delivery section at least partially constructed from a material that transmits ultrasound energy. The apparatus also includes a drug delivery lumen positioned along at least a portion of the sheath, the drug delivery lumen having at least one drug delivery port within the energy delivery section. The apparatus further includes an elongate body having an ultrasound element, the elongate body configured to be movably positioned within the sheath, such that ultrasonic energy can be transmitted from the ultrasound element through the energy delivery section. | 2012-04-12 |
20120089083 | Apparatus for delivering foam - Apparatus, e.g. a syringe, for dispensing foam includes means for ensuring that only foam of adequate quality is dispensed. In use, the syringe may be filled from a pressurised canister which generates foam e.g. for therapeutic use in treating varicose veins. An initial quantity of foam dispensed from the canister may be of inadequate quality in which case it should not be used: the syringe includes means to ensure that this initial quantity of foam is diverted to a waste port or to an internal waste chamber e.g. located in the syringe plunger. Foam dispensed after the initial quantity of poor quality foam is stored in the main barrel of the syringe ready for administration to a patient in need of treatment. | 2012-04-12 |
20120089084 | WOUND HEALING DEVICE - A plasma coating device for treating a wound comprises a plasma chamber having: one or more electrodes, a gas supply inlet, a plasma outlet exposed to ambient pressure, and an ignition system operatively connected to the electrodes for providing a non-thermal equilibrium plasma within the plasma chamber. An aerosol delivery system is operable to introduce a bioresorbable material as an aerosol into the plasma, to produce a coating on the wound surface. | 2012-04-12 |
20120089085 | DIALYSIS METHODS AND SYSTEMS HAVING AUTOCONNECTION AND AUTOIDENTIFICATION - A dialysis system includes at least one pump actuator, a disposable cassette operable with the at least one pump actuator, a plurality of disposable cassette supply connections, and plurality of dialysis solution lines. Each of the plurality of solution lines is connected to a dialysis solution container. The system further includes an autoconnection mechanism configured to connect the plurality of supply connections to the plurality of dialysis solution lines. The system additionally includes an autoidentification system configured to automatically identify information associated with the plurality of dialysis solution lines to determine at least one of (i) dialysis solution type (ii) dialysis solution volume, or (iii) a number of the plurality of dialysis solution supply containers. | 2012-04-12 |
20120089086 | MEDICAL VALVE ASSEMBLY - A medical valve assembly including a rigid external housing and a valve stem of a resilient material. The valve stem includes a passageway for conveying a fluid which has an hourglass shape to create a venturi effect when cleaning the valve stem to improve the efficiency of the cleaning process. The passageway also includes no sharp edges, thus reducing the risk of fluid getting trapped inside the passageway when the medical valve assembly is not in use. Even further, when a needleless syringe is removed from the valve stem, the valve stem expands to an uncompressed state with its top end being generally flush with an end of the housing to present a swabable surface for cleaning purposes. | 2012-04-12 |
20120089087 | Suction Device for Piston Breast Pump - A vertically hand palm pressing suction device for a piston breast pump comprises a casing ( | 2012-04-12 |
20120089088 | MULTI-CONTAINER TRANSFER AND DELIVERY DEVICE - A multi-container transfer and delivery device configured to allow multiple containers to transfer and mix their respective materials and for receiving of the mixed materials to a delivery device. The transfer device comprises a plurality of flow conduits for fluid flow between the multiple containers and the delivery device. Methods of mixing using the device and methods of sterilizing the device are described. A drug mixing kit comprising a multi-container housing with a plurality of flow conduits and a plurality of compartments for receiving containers and a transfer device is also described. | 2012-04-12 |
20120089089 | METHODS OF MAGNETICALLY GUIDING AND AXIALLY ALIGNING DISTAL ENDS OF SURGICAL DEVICES - A magnetic alignment and guidance system is described for use during a surgical or diagnostic procedure within a patient to align and magnetically join the free ends of catheters to form a continuous channel. The system includes two magnetic couplers mounted on the ends of the catheters. One or both of the catheters may be attached to a surgical or diagnostic device, such as a trocar or an endoscope. | 2012-04-12 |
20120089090 | FLUID EJECTION DEVICE AND MEDICAL DEVICE - A fluid ejection device includes: a pressure chamber; an actuator having a displacement plane that varies the volume of the pressure chamber; a delivery channel pipe communicating with the pressure chamber; a first reflection surface of pressure wave formed as part of a paraboloid of revolution that reflects a plane pressure wave by displacement of the actuator, the plane pressure wave propagating through the pressure chamber; and a second reflection surface of pressure wave formed as part of a paraboloid of revolution or an ellipsoid of revolution which is disposed so as to face the first reflection surface of pressure wave, wherein the first reflection surface of pressure wave and the second reflection surface of pressure wave have a common first focus, and a pressure wave reflected from the second reflection surface of pressure wave propagates through the delivery channel pipe and ejects fluid. | 2012-04-12 |
20120089091 | FLUID DISPENSER - A dispensing device for dispensing pain management medicaments to a patient comprising first and second threadably interconnectable sub-assemblies. The first of these sub-assemblies houses a novel collapsible fluid reservoir defining component while the second comprises a fluid delivery and control assembly that includes a novel flow control means that functions to control the flow of medicinal fluid from the fluid reservoir of the collapsible reservoir defining component toward the patient via a plurality of fluid flow control passageways. | 2012-04-12 |
20120089092 | METHOD FOR PROVIDING SURGICAL ACCESS - One embodiment is directed to a method for advancing a needle into a tissue structure, comprising: advancing a distal end of a needle insertion assembly, the assembly comprising an insertion member coupled to a tissue interface indentor member and movably coupled to an elongate needle member, against a targeted tissue structure such that a distally protruding shape feature of the tissue interface indentor member engages one or more portions of the targeted tissue structure adjacent a distal tip of the elongate needle member at a position at which the elongate needle member distal tip is configured to be advanced through the insertion member and into the tissue structure, and locally changes an available angle of penetration between such portions and the distal tip of the elongate needle member; and inserting the elongate needle member relative to the insertion member and tissue interface indentor member. | 2012-04-12 |
20120089093 | SEAL ARRANGEMENT FOR MINIMALLY INVASIVE DIAGNOSTIC OR SURGICAL INSTRUMENTS - A sealing device is disclosed which is intended for use with an access device, such as a trocar, canula or the like, that passes from the outside to the inside of a patient, through an incision in the patient during a minimally invasive diagnostic or surgical procedure to secure one or more tethers, tubes, or the like to the exterior surface of the access device. The sealing device secures one or more tethers in position between the access device and an incision by creating a smooth profile for the access device and tethers and substantially seals against insufflation leakage. | 2012-04-12 |
20120089094 | TROCAR SEAL WITH RETRACTION INDUCED HINGE - A trocar comprising an alignment channel and an instrument seal comprising a bending portion and a base portion. The bending and base portions of the instrument seal are spaced relative the alignment channel such that when a surgical instrument is retracted the bending portion inverts and the lip does not enter the alignment channel. | 2012-04-12 |
20120089095 | NEEDLE ARRAY ASSEMBLY AND METHOD FOR DELIVERING THERAPEUTIC AGENTS - A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment. | 2012-04-12 |
20120089096 | EXTERNAL END DEVICE FOR PERMANENT CATHETERS - An external end device for permanent catheters includes a container that houses two taps being provided with knobs and having, at one hand, a first connector for the connection to the catheters and, at the other hand, second connectors projecting from the container for the connection to an external equipment. The first connector is connected to the catheter by a coupling exiting the container and externally holding a subcutaneous cuff designed to be positioned in the subcutaneous tissue of the patient's body. The second connectors are provided with caps surrounded by the disposable absorbent material being received in the closure lid and having spaces for housing the caps for protecting them externally from a bacterial attack by the antiseptic substance by which it is impregnated. Further an implantation method of the device in a patient is disclosed. | 2012-04-12 |
20120089097 | MOUNTING ARRANGEMENT AND COUPLING ASSEMBLY FOR A DRUG-DELIVERY DEVICE - A mounting arrangement for a drug-delivery device is proposed, the mounting arrangement comprising: a plug element with a longitudinal axis (L) and a housing part having a recess with a side wall which is adapted to receive the plug element. At least one of the plug element or the side wall of the recess are provided with a protrusion for fixing the plug element in a given position relative to the housing part by a force-fit engagement. Furthermore, a coupling assembly is proposed, the coupling assembly comprising the plug element and the housing part being mechanically coupled to each other. | 2012-04-12 |
20120089098 | Drug Delivery Device - The present invention relates to a drug delivery ( | 2012-04-12 |
20120089099 | SPRING ELEMENT FOR A DRUG DELIVERY DEVICE, USE THEREOF AND DRUG DELIVERY DEVICE - A spring element for a drug delivery device is proposed, the spring element comprising multiple windings with two windings being mechanically coupled to each other by a rigid transverse connection. Furthermore, a drug delivery device comprising such a spring element and using such a spring element in a drug delivery device are proposed. | 2012-04-12 |
20120089100 | Pen-Type Injector - A housing for a dispensing apparatus. The housing comprising a main housing and a dose dial sleeve. The dose dial sleeve comprising a helical groove configured to engage a threading provided by the housing. A dose knob is disposed near a proximal end of the dose dial sleeve and a piston rod is provided within the housing. The piston rod is non-rotatable during a dose setting step. A driver comprises an internal threading near a distal portion of the driver and is adapted to engage an external thread of the piston rod. A tubular clutch is located adjacent a distal end of the dose knob and operatively coupled to the dose knob. The dose dial sleeve may extend circumferentially around at least a portion of the tubular clutch. | 2012-04-12 |
20120089101 | Surgical Fluid Transfer Apparatus - A surgical apparatus includes a hub, a closure valve, an internal seal member, and a spring. The hub defines an internal chamber. The closure valve is disposed within the internal chamber and defines an internal bore extending therethrough. The closure valve is movable relative to the hub between a first position, substantially sealing the internal chamber, and a second position, establishing a fluid passage extending completely through the hub. The internal seal member is disposed within the internal bore of the closure valve and is movable relative to the closure valve between a closed position, substantially sealing the internal bore, and an open position, establishing an internal passage, different from the fluid passage, extending completely through the closure valve. The spring is disposed within the internal chamber and is configured to bias the internal seal member towards the closed position, thereby biasing the closure valve towards the first position. | 2012-04-12 |
20120089102 | Microvalve Protection Device and Method of Use for Protection Against Embolization Agent Reflux - An endovascular valve device for use in a vessel during a therapy procedure includes a catheter having at its distal end a valve. The valve is constructed of a braid of elongate first filaments coupled together at their proximal ends in a manner that the first filaments are movable relative to each other along their lengths. The first filaments have a spring bias that radially expands the valve. A filter is provided to the braid formed by electrostatically depositing or spinning polymeric second filaments onto the braided first filaments. The lumen of the catheter is in communication with the center of the valve. | 2012-04-12 |
20120089103 | Medical Device For Healing Wounds and Skin Diseases - The present invention discloses a medical device having a disposable member for treating dermatological diseases and topical pathogeneses. The device comprises, inter alia, at least one inner layer at least partially made of a non-woven material, being in physical contact with at least a part of the derma having the dermatological diseases; at least one external impervious and flexible layer, at least partially made of material selected from a group consisting of silicone, rubber and polymer, enveloping the inner layer; and, source of hypertonic solution wetting the inner layer such that the inner layer is continuously immersed with the hypertonic solution and a constantly hypertonic environment around the derma is maintained. The inner layer is disposable and reversibly detachable to the enveloping external layer such that frequent displacement of the inner layer is possible, topical pathogeneses are being removed and dermatological diseases are being treated. | 2012-04-12 |
20120089104 | ANTIVIRAL TRANSDERMAL PATCH AND METHOD FOR PRODUCING THE SAME - An antiviral transdermal patch including a backing layer, a viscous polymer layer, and a protection film layer. The viscous polymer layer includes an antiviral agent, a viscous polymer, and a transdermal enhancer. The transdermal enhancer is laurocapram or a mixture thereof. The antiviral agent is a nucleoside antiviral drug with a daily delivery rate of less than 100 mg/day. The patch effectively promotes the penetration of a nucleoside antiviral agent into the blood circulation and avoids enzymolysis in the gastrointestinal tract and the first pass effect of the liver and reduces side effect of drugs, thereby inhibiting the replication of target viruses and reducing viral DNA level in the serum. A method for producing the patch is also provided. The raw materials involved in the invention are easily purchased from the market at a low cost. | 2012-04-12 |
20120089105 | SELF-ADHESIVE SKIN PATCH AND COMBINATION SET FOR COSMETIC SKIN CARE - The present invention relates to a skin patch comprising a matrix adhering to the skin and containing at least one active cosmetic substance and a combination with a skin wrapping to generate an effective compression for the treatment of cellulite and/or striae. | 2012-04-12 |
20120089106 | ABSORBENT ARTICLE - An absorbent article includes a topsheet having a contact surface in contact with the skin of a wearer; a liquid-impermeable backsheet through which a liquid does not pass; and an absorber provided between the topsheet and the backsheet, a cooling sensation material including a refresher agent in the topsheet or between the topsheet and the backsheet. On the outside of the planar direction of the topsheet from the contact region in which an excretion unit of the wearer is in contact in the topsheet, there is a region having a greater amount of the cooling sensation material per unit area than the amount of the cooling sensation material per unit area in the contact region. | 2012-04-12 |