15th week of 2009 patent applcation highlights part 35 |
Patent application number | Title | Published |
20090093318 | DEVICE AND METHOD FOR GENERATING VORTEX - A device and method for generating a visible vortex for display or educational purposes. A container houses a two-phase fluidic system of a primary fluid, such as water, and a secondary fluid such as silicone fluid carrying a powder which has no affinity for the primary fluid. The two-phase fluidic system may be stirred using a stir bar or pump to generate the vortex. | 2009-04-09 |
20090093319 | TRAINING DEVICE FOR SWING DEVELOPMENT - A training device | 2009-04-09 |
20090093320 | Face Structure of Golf Club - A face structure of golf club comprising club face ( | 2009-04-09 |
20090093321 | Golf club head structure - A golf club head structure includes a body portion, a hitting plate portion, and a club body combining portion. The body portion has a first junction surface forming a first hook angle therewith. The hitting plate portion has a hitting surface and a second junction surface with a buffer region spaced there-between. The second junction surface forms a second hook angle with the hitting plate portion, and butts against and attaches to the first junction surface on the same plane. The club body combining portion is provided for combining a club body. Therefore, a joint structure with a junction portion as a plane, capable of not being located on the surface of the club head and spaced by a buffer region with the hitting surface, is formed, which is applicable for solving the combination problem of the junction surface on the same plane that the casting is deformed. | 2009-04-09 |
20090093322 | Tee-setting device - A device which positions a golf tee to a predetermined height above the ground. The cup of a standard golf tee fits into a circular recess within the head of the device while the shaft of the tee is held against a groove along the body of the device. The device is a rigid, unitary piece with the vertical distance from the circular recess to the bottom of the body equal to the desired height of the tee above the ground. With the tee held in place within the device, a length of the tee's shaft extends past the bottom of the tee-setting device. The golfer applies pressure to the top of the tee-setting device to push the point of the tee into the ground until the bottom of the tee-setting device meets the ground. Upon removal of the tee-setting device, the tee remains positioned at exactly the desired height. | 2009-04-09 |
20090093323 | GOLF TEE AND METHOD OF MAKING SAME - A golf tee is provided for supporting a golf ball. The golf tee is adapted to sit on top of the ground and comprises a support rim or at least three support points for supporting a golf ball and an open body having a lower end suitable for placement on the ground and an upper end suitable for connection to the support rim. An optional neck may be used connecting the upper end of the open body to the support rim. The open body comprises a plurality of support columns and optionally one or more support rings connecting the support columns. The support columns are separated by holes thereby increasing the surface area of the golf tee. The open body and holes are adapted to receive grass and can allow for substantial level placement of the tee relative to the ground even when the grass is dense or longer. The support columns and holes result in a golf tee having a high drag and relatively low weight thereby providing a golf tee which travels a relatively short distance when struck by a swinging golf club. | 2009-04-09 |
20090093324 | CROQUET MODIFYING GAME - A croquet modifying game includes at least one indicator such as a playing card. The playing card includes player instructions, wherein the player instructions modify standard play of a game of croquet. A corresponding method of playing croquet is provided. | 2009-04-09 |
20090093325 | COMBINATION PITCHING AID AND BATTING TEE - Described herein is a combination pitching aid and batting tee apparatus. The apparatus includes a base having a front and a rear, a stand extending upwardly from the base, a support rod extending upwardly from the stand, and an arm extending outwardly from the support rod. The arm includes a target associated therewith that can be adjusted vertically and horizontally. The apparatus includes a screen having a top end and a bottom end and a support assembly having a top end and a bottom end that extends upwardly from the base. The bottom end of the screen is attached near the front of the base and the top end of the screen is attached to the support assembly. The support rod can be replaced with a batting tee. | 2009-04-09 |
20090093326 | Hockey Stick - A hockey stick having a composite blade and a shaft is disclosed. The composite blade includes a heel section that is recessed relative to the front and back faces of the blade. The recessed heel section is configured to be received by a hockey stick shaft or an adapter member configured to connect the blade to the shaft. The composite blade preferably comprise a foam inner core overlaid preferably with substantially continuous fibers disposed in a matrix material and may include an internal bridge structure extending from one side of the blade to the other. The blade may also be preferably comprised of a core comprising non-continuous fibers disposed within a matrix material. In another aspect, processes for manufacturing the previously described hockey stick blade(s) are described. | 2009-04-09 |
20090093327 | YOUTH ORIENTED SPORTSBALLS - Inflatable sportsballs such as volleyballs, soccer balls, basketballs, and footballs are disclosed having various volume/weight, surface area/weight, and or cover layer/carcass thickness ratios. Such sportsballs are particularly suitable for youth. | 2009-04-09 |
20090093328 | Toothed belt pulley - The invention describes a belt pulley ( | 2009-04-09 |
20090093329 | CHAIN NOISE REDUCTION DEVICE - A cushion ring ( | 2009-04-09 |
20090093330 | Hybrid vehicle drive system - A drive system of a hybrid vehicle, including an engine, a first electric motor, a second electric motor operatively connected to a drive wheel of the hybrid vehicle, and two planetary gear mechanisms, and wherein the two planetary gear mechanisms have at least four rotary elements arranged to permit the drive system to be placed in a selected one of a first operation mode in which the rotary element connected to the engine and the rotary element connected to the first electric motor are disposed on opposite sides of the rotary element connected to the drive wheel and the second electric motor, as seen in a collinear chart in which the four rotary elements are located at respective four different positions along a base line, and a second operation mode in which the rotary element connected to the first electric motor and the rotary element connected to the drive wheel and the second electric motor are disposed on opposite sides of the rotary element connected to the engine, as seen in said collinear chart. | 2009-04-09 |
20090093331 | Hybrid drive device - A hybrid drive device includes an input member connected to an engine; an output member connected to a wheel; a first rotating electrical machine; a second rotating electrical machine connected to the output member; and a differential gear device including at least four rotational elements. The input member, the output member, and the first rotating electrical machine are respectively connected to different rotational elements of the differential gear device. The output member is capable of selectively connecting to one of two rotational elements of the differential gear device to which neither the input member nor the first rotating electrical machine is connected. | 2009-04-09 |
20090093332 | ELECTRICALLY VARIABLE TRANSMISSION HAVING THREE PLANETARY GEAR SETS WITH TWO FIXED INTERCONNECTIONS - The electrically variable transmission family of the present invention provides low-content, low-cost electrically variable transmission mechanisms including first, second and third differential gear sets, a battery, two electric machines serving interchangeably as motors or generators, and five selectable torque-transfer devices. The selectable torque transfer devices are engaged in combinations of two or three to yield an EVT with a continuously variable range of speeds (including reverse) and four or five mechanically fixed forward speed ratios. The torque transfer devices and the first and second motor/generators are operable to provide five operating modes in the electrically variable transmission, including battery reverse mode, EVT reverse mode, reverse and forward launch modes, continuously variable transmission range mode, and fixed ratio mode. | 2009-04-09 |
20090093333 | AXLE ASSEMBLY WITH ELECTRO-HYDRAULIC CLUTCH CONTROL SYSTEM - An axle assembly for a vehicle. The axle assembly includes an input shaft, a first and second output shaft, and a differential assembly. The axle assembly also includes a clutch assembly with an input member coupled to the differential assembly, an output member coupled to one of the first output shaft and the second output shaft, and a clutch member that selectively couples the input and output members. The axle assembly also includes a pump that supplies pressurized fluid to the clutch to control coupling of the input and output members. The axle assembly further includes a motor that drives the pump. The speed of the motor is controllable in order to change a fluid pressure supplied by the pump. The change in fluid pressure from the pump actuates the clutch member to thereby vary the torque between the first output shaft and the second output shaft. | 2009-04-09 |
20090093334 | Method and Kit to Convert an Open Differential to a Limited Slip Differential - A kit and method of using the kit to convert an open differential in a golf cart to a limited slip differential by replacing the side gears with side gears containing an integrated clutch surface that engage a spring loaded case containing an integrated clutch surface. | 2009-04-09 |
20090093335 | TRANSMISSION AND POWER TRANSMITTING SYSTEM - A transmission includes: a plurality of rotating elements interposed between a driving source and an output portion; a rotating member that rotatably supports one of the rotating elements and is formed at a radially outer portion thereof with a plurality of recesses or protrusions; a support member having a surface, that is facing the rotating member, and a plurality of protrusions or recesses that are formed in a radially inner portion thereof and engage with the recesses or protrusions of the rotating member, the rotating member being mounted in the support member such that the rotating member is not able to rotate; and a friction producing mechanism that is provided between the rotating member and the above-indicated surface of the support member and is arranged to produce a frictional force between the rotating member and the surface of the support member. | 2009-04-09 |
20090093336 | Vehicle Creep Control in a Hybrid Electric Vehicle - In a powertrain that includes wheels for driving a vehicle, an engine including a crankshaft, a machine driveably connected to the crankshaft and able to operate alternately as an electric motor and electric generator, a transmission including an input clutch driveably connected to the crankshaft and an output driveably connected to at least two of the wheels, and an electric storage battery having a variable state of charge and electrically connected to the machine, a method for controlling vehicle creep including adjusting a torque capacity of the input clutch to a desired magnitude of input clutch torque transmitted to the wheels, determining a desired change in torque produced by the machine such that a speed of the crankshaft is controlled to a desired idle speed, using the magnitude of input clutch torque capacity and the desired change in torque produced by the machine to determine a desired magnitude machine torque, and using the machine to produce said desired magnitude of machine torque. | 2009-04-09 |
20090093337 | Holding a Hybrid Electric Vehicle on an Inclined Surface - In a powertrain that includes wheels supporting a vehicle, an engine, a first machine able to operate alternately as an electric motor and electric generator, a second machine electric able to operate as an electric motor, and an electric storage battery having a variable state of charge, a method for holding the vehicle stationary on an incline including determining a magnitude of torque at the wheels required to hold the vehicle on the incline, determining whether the state of charge is low or high relative to a reference state of charge, determining whether a temperature of the first machine is low or high relative to a first reference temperature, and whether a temperature of the second machine is low or high relative to a second reference temperature, using the engine and the machines in various combinations to produce the required torque at the wheels. | 2009-04-09 |
20090093338 | HYDRAULIC CONTROL UNIT - A hydraulic control system of a friction device where fail-safe is required is provided with one oil pressure switch and one pressure changeover valve. The pressure changeover valve is switched by auxiliary oil pressure based on an operation of the oil pressure control valve. When an auxiliary port communicates with an input port and the pressure changeover valve is switched to the filling determination side, the oil pressure switch is turned on and “filling determination” can be carried out. When the auxiliary port is disconnected from the input port, the pressure changeover valve is switched to the fail-safe determination side. The oil pressure switch is supplied with the same driving oil pressure as of the friction device and “fail-safe determination” can be carried out from the on/off state of the oil pressure switch. | 2009-04-09 |
20090093339 | TORQUE CONVERTER CLUTCH CONTROL - A powertrain for a vehicle includes an engine having an output and a transmission selectively driven by the output of the engine. A torque converter is disposed between the engine and the transmission for selectively coupling the output of the engine to the transmission. A controller is in communication with the engine and the torque converter and controls a pressure: within the torque converter based on an input parameter supplied to the engine. | 2009-04-09 |
20090093340 | Shift Control Device for Work Vehicle - A shift control device for a work vehicle that has a stepped automatic transmission includes: a control device that controls an engine rotation rate at the work vehicle and the stepped automatic transmission; a forward/reverse switchover member that outputs a forward/reverse switchover command for the work vehicle; and an operation quantity detection device that detects an accelerator pedal operation quantity in the work vehicle is operated. As the forward/reverse switchover command is output via the forward/reverse switchover member, the control device executes forward/reverse switchover control for the stepped automatic transmission and also controls the engine rotation rate so as to decrease the engine rotation rate gradually to a target lower limit value selected to ensure that a reverse rotation of a turbine runner at a torque converter in the work vehicle does not occur. | 2009-04-09 |
20090093341 | Music and Accelerometer Combination Device for Collecting, Converting, Displaying and Communicating Data - A method for integrating and managing data is provided that includes interacting with an end user via a music and health component combination device, the device including: a health component that is operable to track data by the user and a music module operable to play music for the user. The device further includes a memory and a processor operable to convert data from the health component into one or more metrics based on data received from the memory. In other embodiments, the device can display a category of music, such as an album or a play list. The device also includes a dimming function that allows certain parameters being displayed by the device to be highlighted, emphasized, or deemphasized. | 2009-04-09 |
20090093342 | Circular yoga or exercise mat - A yoga or exercise mat circular in form from between four feet and eight feet in diameter. The circular mat will allow the yoga practitioner to be able to perform various poses and exercises without having to step off or turn the mat during exercising. The circular Yoga mat will also provide for proper spacing of yoga students during classes as the circular form eliminates the problem of overlapping space for students and teachers. The circular yoga mat will greatly benefit the yoga or exercise practitioner by providing full coverage, padding and protection during exercising while at the same time providing and protecting the space and comfort of those using the mat. | 2009-04-09 |
20090093343 | Trampoline balance beam - A balance beam for training gymnasts has been invented. The balance beam has the capability of absorbing the downward momentum of a gymnast landing on the beam and then providing a near equal upward thrust to the gymnast allowing greater heights and longer air time in an immediately following jump thus facilitating the quicker learning of gymnastic skills. To achieve this, the beam is supported within a frame of similar dimension as the beam. The components which support the beam within the frame are located at each end of the beam and consist of a special arrangement of springs and elastic straps which represent the embodiment of the invention. | 2009-04-09 |
20090093344 | GYMNASTICS SAFETY AND TRAINING AID BAR SLEEVES FOR HIGH BAR AND OTHER APPARATUS - An apparatus for use with gymnastics equipment having a bar which is held by a gymnast, the apparatus including: one or more sleeves surrounding at least a portion of the bar and rotating relative to the bar while the gymnast holds an outer portion of the one or more sleeves; at least one harness for securing around at least a portion of a torso of a gymnast; and one or more straps fixed at a first end to the harness and to the one or more sleeves at a second end; wherein the one or more sleeves have one or more slots for accepting the second end of the one or more straps. | 2009-04-09 |
20090093345 | Apparatus for the Separating and Stretching of Toes and Fingers - A toe and finger stretching device comprising a separator for receiving at least two toes there within, the separator including a duality of shaped openings, each shaped opening adapted for receiving an individual digit of the human foot and the shaped openings being from 0.25 to 2.0″ in length, the separator further comprising a stretch width section, said stretch width section interposed between the shaped openings, the separator spreading the toes between 0.25 to 2.0″ in width; such that when the toes are inserted into the shaped openings the toes are contactless. | 2009-04-09 |
20090093346 | CROSS TRAINER EXERCISE APPARATUS - An elliptical exercise apparatus. The exercise apparatus generally includes a frame, a pair of cranks pivotally connected to the frame and configured to rotate about a common axis, first and second reciprocating members, first and second support members, and first and second foot engaging members. The first end portion of each of the first and second reciprocating members may be pivotally coupled to the frame. The first portion of each of the first and second support members may be pivotally coupled to the corresponding crank, and the second portion of each of the first and second support members may be pivotally coupled to the second end portion of the corresponding reciprocating member. Each foot engaging member is coupled to a corresponding support member and may generally move through a closed path. Handle members may be coupled to the support members and may generally move through a closed path. | 2009-04-09 |
20090093347 | INTEGRATED FOLDING MECHANISM OF A TREADMILL - An integrated folding mechanism of a treadmill having a slide pusher supported by a pneumatic cylinder at the bottom of a platform frame thereof. In this way, the rear support may be pushed upward to bring the platform frame in a vertical stable folding position or in a flat ground-touching position when the platform frame is moved upward and downward. Meanwhile, a coupling rod is pivotally interposed between the rear support and an L-shaped handrail assembly. Under the action of an elastic element, the handrail assembly is movable with the platform frame for creating a synchronic folding and extending action. | 2009-04-09 |
20090093348 | EXERCISE TOOL AND WEIGHT MEMBER THEREOF - A weight member for exercise includes a resilient shell that defines an inner chamber. The inner chamber contains a filling having weighting and shock-absorbing properties. The filling includes a high specific weight material and one of a foamable low specific weight material and a non-foamable low specific weight material. An exercise tool including a handle and at least one weight member attached to the handle is also disclosed. | 2009-04-09 |
20090093349 | Total body combat conditioning c4 bar - A portable, multi-configurable exercising device which allows a full range of traditional exercises and also marital arts movements to be performed in correct fashion on a compactable, weight and tension adjustable apparatus. All components are collapsible within itself and also reconfigures in such a way as to form a multi-exercise embodiments. Several components are adjustably de-attachable thereby creating multiple embodiments and allowing the performance of many exercises. | 2009-04-09 |
20090093350 | Compact and light exercise machine providing variable resistance and variable range of motion - A small, light personal fitness device offers capability to perform both light and heavy exercises. The invention employs flywheels ( | 2009-04-09 |
20090093351 | Freely moveable strength training device for strengthening the body musculature, which can be loaded by pulling - A freely movable strength training device for strengthening the body musculature can be loaded by pulling. The device has a housing and at least one spring element arranged in the housing, which can be loaded via muscular strength. The device has at least two pull elements which can be actuated by a user. All pull elements are fastened on the spring element. | 2009-04-09 |
20090093352 | BODY-BUILDING DEVICE SUBSTANTIALLY IN THE FORM OF A "CLOVERLEAF", WHICH PERMITS MUSCULAR WORKING OF THE LOWER AND UPPER LIMBS - The present invention relates to a device of the type for building up the upper and lower limbs in particular, which has at least two resistance forces, and preferably three forces. These forces are obtained without adding a supplementary part, and without any particular adjustment. The device has a substantially oval shape ( | 2009-04-09 |
20090093353 | Device And Method For Knee Joint Rehabilitation - A device for increasing the range of motion of a patient's knee joint generally includes a frame, a lever member pivotally coupled to the frame at a first location, and an actuator pivotally coupled to the frame at a second location. The frame supports the patient in a manner that allows motion of the patient's knee joint, and the lever member bears against a portion of the patient's body below the knee joint. The actuator is also pivotally coupled to the lever member. When operated by a controller, the actuator generates a translational input that rotates the lever member relative to the frame and thereby stretches the patient's knee joint in a desired direction. | 2009-04-09 |
20090093354 | Case Erector - A case erector is configured to open folded cases. In one example, the case erector includes a planar bearing surface. A semi-circular channel is defined in the planar bearing surface about a center point. Additionally, a notch is located so that the planar bearing surface does not extend to the center point of the semi-circular channel. A plate is in contact with the planar bearing surface. The plate has at least one flange sized for travel within the semi-circular channel so that the plate rotates against the planar bearing surface in a circular manner about the center point. A notch is defined in the plate so that the plate does not extend to the center point of the semi-circular channel. An arm is connected to the plate so that the plate and the arm rotate together with respect to the planar bearing surface. In operation, a folded edge of a folded case is positioned at the center point. One or two arms, moved by plates rotating on bearing surfaces, attach to and open the folded case. | 2009-04-09 |
20090093355 | CASE ERECTOR AND SEALER APPARATUS - An automated case erecting apparatus for use in erecting case blanks includes a case blank feeder configured to hold a plurality of upstanding case blanks arranged face-to-face. The case blank feeder includes a path along which the case blanks are directed. A case erecting assembly receives a case blank from the case blank feeder at a case receiving location. The case erecting assembly includes a first arm carrying a first gripper element and a second arm carrying a second gripper element. The first arm and associated first gripper element are arranged and configured such that the first gripper element grips a first flap of the case blank. The second arm and associated second gripper element are arranged and configured such that the second gripper element grips a second flap of the case blank. The case erecting assembly is configured to move in a conveying direction from the case receiving location toward a case bottom fold and seal station to carry the gripped case blank toward the case bottom fold and seal station. | 2009-04-09 |
20090093356 | OPTICAL GLASS - Optical glass constituted by an amorphous matrix and crystal grains dispersed in the amorphous matrix, wherein the amorphous matrix comprises a first oxide of at least one of silicon oxide and phosphor oxide and a second oxide of at least one of titanium oxide and zirconium oxide, and wherein the crystal grains is at least one of titanium oxide, zirconium oxide and silicon, an average grain size of the titanium oxide grain being 3 nm to 20 nm, and the average grain size of the silicon crystal being 3 nm to 8 nm. | 2009-04-09 |
20090093357 | OPTICAL GLASS AND LENS USING THE SAME - The invention provides: an optical glass which comprises, in terms of % by mass on the basis of oxides, 13-27% of B | 2009-04-09 |
20090093358 | Porous Silicone Carbide - A porous refractory product includes a matrix of sintered silicon carbide having a porosity of about 45% to about 65%. The matrix is formed by heating in a noble gas atmosphere a cast preform including a mixture of alpha-silicon carbide and boron carbide each having a particle size of less than about 1 micron. The heating causes the formation of gaseous SiO within the silicon carbide matrix, which, in turn, forms pores having an average size of less than about 1 micron. The porous refractory products herein are suitable for use in a variety of applications including for use in high temperature particulate filtering applications. | 2009-04-09 |
20090093359 | Fiber Fabric Having VOC Removing Function - A fiber fabric having a VOC removing function according to the present invention has a hydrophobic inorganic porous substance and a photocatalyst adhered to at least a part of the fiber fabric with binder resin. With this, not only formaldehyde and acetaldehyde but also VOCs having an aromatic ring such as toluene and xylene can be adequately decomposed, which prevents cross-contamination by intermediate products formed during the decomposition. | 2009-04-09 |
20090093360 | METHOD FOR PREPARING CATALYST SUPPORTS AND SUPPORTED CATALYSTS FROM SINGLE WALLED CARBON NANOTUBES - A new method for preparing a supported catalyst is herein provided. A carbon nanotube structure such as a rigid porous structure is formed from single walled carbon nanotubes. A metal catalyst is then loaded or deposited onto the carbon nanotube structure. The loaded carbon nanotube is preferably ground to powder form. | 2009-04-09 |
20090093361 | PHOTOCATALYST DISPERSION LIQUID AND PROCESS FOR PRODUCING THE SAME - To provide a photocatalyst dispersion liquid obtained by dispersing titanium oxide photocatalyst particles and tungsten oxide photocatalyst particles in a dispersion medium, where the surfaces of both titanium oxide photocatalyst particles and tungsten oxide photocatalyst particles are charged positively or negatively. In the photocatalyst dispersion liquid, the titanium oxide photocatalyst particles and the tungsten oxide photocatalyst particles, which are dispersed in the dispersion medium, are not aggregated easily, and a solid-liquid separation is not generated. | 2009-04-09 |
20090093362 | Stable aqueous dispersions of colour developer - Storage-stable compositions comprising a colour developer, an anionic dispersant and a thickening agent as well as heat-sensitive recording materials comprising such compositions, a process for its manufacture and its use. | 2009-04-09 |
20090093363 | USE OF MACROLIDES IN PEST CONTROL - There is now described a method of controlling pests with macrolide compounds; more specifically a method of protecting plant propagation material and plant organs formed at a later point in time from attack by pests, characterized in that a pesticide comprising, as pesticidally active compound, at least one macrolide compound as active ingredient and at least one auxiliary in close spatial proximity to, or spatially together with, planting or applying the propagation material is employed to the site of planting or sowing. | 2009-04-09 |
20090093364 | Resin Composition Containing Release-Controlled Agricultural Chemical, Production Method Thereof, and Agricultural Chemical Formulation - A resin composition containing an agricultural chemical in which the release of an agricultural chemical active ingredient is controlled; a production method thereof; and an agricultural chemical formulation; in other words, an agricultural chemical-containing resin composition which is a composition containing an agricultural chemical active ingredient, a resin, and a fatty acid metal salt, and characterized in that the composition is either in a compatible state or forming a matrix; its production method; and an agricultural chemical formulation including at least one of the agricultural chemical-containing resin compositions; in addition to an agricultural chemical-containing resin composition which is a composition containing an agricultural chemical active ingredient, a (meth)acrylate based resin, and a release controlling agent, and characterized in that the composition is either in a compatible state or forming a matrix; its production method; and an agricultural chemical formulation including at least one of the agricultural chemical-containing resin compositions, are provided. | 2009-04-09 |
20090093365 | Multilayer seed coating - In accordance with the present invention, various types of seeds are coated with a coating comprising a) a base buildup layer comprising a porous composition such as pumice; b) an intermediate build up layer comprising a silicate composition such as talc or mica; and c) an outer layer comprising a carbon-based composition such as graphite. A binder is optionally added to one or more layers. Preferably, each layer is applied to a seed in either a batch or continuous process using conventional methods of coating. Hybrid corn and sunflower seeds may be coated in accordance with the present invention resulting in a substantially uniform size seed. | 2009-04-09 |
20090093366 | Novel Herbicide Resistance Genes - The subject invention provides novel plants that are not only resistant to 2,4-D and other phenoxy auxin herbicides, but also to aryloxyphenoxypropionate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention alone or “stacked” together with another herbicide resistance gene, preferably a glyphosate resistance gene, so as to provide broader and more robust weed control, increased treatment flexibility, and improved herbicide resistance management options. More specifically, preferred enzymes and genes for use according to the subject invention are referred to herein as AAD (aryloxyalkanoate dioxygenase) genes and proteins. No α-ketoglutarate-dependent dioxygenase enzyme has previously been reported to have the ability to degrade herbicides of different chemical classes and modes of action. This highly novel discovery is the basis of significant herbicide tolerant crop trait opportunities as well as development of selectable marker technology. The subject invention also includes related methods of controlling weeds. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the formation of, and controlling, weeds that are resistant (or naturally more tolerant) to one or more herbicides such as glyphosate. | 2009-04-09 |
20090093367 | Canola Plants with High Oleic and Low Linolenic - Canola plants with high oleic acid and low linolenic acid content are disclosed. In addition, the canola plants of the invention are resistant to imidazolinone herbicides and are resistant to blackleg. The canola plants of the invention also have low total glucosinolate content. There is also provided a method for controlling weeds in a field of canola plants wherein the canola plants are herbicide resistant. | 2009-04-09 |
20090093368 | Methods for preparing granular weed control products having improved distribution of agriculturally active ingredients coated thereon - A method for improving the distribution of agriculturally active ingredients on the surface of granules includes preparing a sprayable liquid solution of at least one agriculturally active ingredient, and applying the sprayable liquid solution on the granules by spraying the liquid solution in atomized form onto the surface of the granules to provide a coating on the surface of the granules which enables substantially all of the agriculturally active ingredient on the granule to be solubilized by the naturally occurring moisture present on the foliage of a treated weed for absorption into the cells of the treated weed when the granules are applied thereto. | 2009-04-09 |
20090093369 | SUPERCONDUCTING SYNCHRONOUS MACHINE - Disclosed herein is a superconducting field coil of a homopolar type superconducting synchronous machine. The superconducting synchronous machine includes a superconducting field coil which comprises a single or double pancake coil formed by winding a superconducting wire, a core-type rotor which is made of a magnetic material, and an armature winding excited to three phases on a surface of a core of a stator. The field coil of the homopolar type superconducting synchronous machine is not rotated when the machine is in operation. Thus, there is no part for coupling the rotating field coil to a stationary cryo-cooler for cooling a refrigerant, so that the structure is simple, reliability is high, and various cooling methods are available. | 2009-04-09 |
20090093370 | SUPERCONDUCTING COIL AND SUPERCONDUCTING CONDUCTOR FOR USE THEREIN - The invention offers a superconducting coil that has the shape of a pancake formed by winding a superconducting conductor. The superconducting conductor is composed of a tape-shaped (Bi, Pb)2223-based superconducting wire and a tape-shaped thin-film RE123-based superconducting wire that are electrically connected in parallel with each other. The coil generates only a low voltage in the steady-operation state, limits the generated voltage to a low level even in a state where an external disturbance enters for some reason, and is therefore less susceptible to quenching. Consequently, the coil can be operated stably in both states. The invention also offers a superconducting conductor to be used to form the coil. | 2009-04-09 |
20090093371 | MEMBRANE ARRAYS AND METHODS OF MANUFACTURE - The invention relates to G protein-coupled receptor (GPCR) microarrays on porous substrates for structural or functional analyses of GPCRs, and methods of preparing porous substrate surfaces for receiving membranes that comprise GPCRs. In one embodiment, a GPCR microarray of the invention comprises a membrane adhered to an upper surface of a porous substrate, the membrane spanning across a plurality of pores on the porous substrate to form a plurality of cavities having sufficient geometry to permit entry of assay reagents into each cavity, thereby allowing access of assay reagents to both sides of GPCR in the membrane. | 2009-04-09 |
20090093372 | METHODS FOR INCREASING DEFINITIVE ENDODERM PRODUCTION - Disclosed herein are methods for increasing the production of definitive endoderm cells from pluripotent stem cells. Also disclosed herein are agents capable of increasing definitive endoderm cell production. | 2009-04-09 |
20090093373 | DNA MICRO-ARRAY HAVING STANDARD PROBE AND KIT INCLUDING THE ARRAY - To provide a DNA micro-array having a nucleic acid probe immobilized on a substrate, which is used to detect a molecule of a target nucleic acid contained in a sample and has a substantially complementary base sequence to the target base sequence of the nucleic acid molecule, including at least one probe selected from the group consisting of: at least one internal standard probe for assay of PCR of the target nucleic acid; at least one external standard probe for a detection operation and assay of an amount of the probe; and a probe for measurement of the amount or density of the nucleic acid probe, formed by the same method as the nucleic acid probe. | 2009-04-09 |
20090093374 | METHOD OF ARRAYING CELLS AT SINGLE-CELL LEVEL INSIDE MICROFLUIDIC CHANNEL AND METHOD OF ANALYSING CELLS USING THE SAME, AND CELL ANALYSIS CHIP USED FOR CARRYING OUT THE SAME - Provided are a method of arraying cells at a single-cell level effectively, simply and economically, a method of analyzing cells using the same, and a cell analysis chip used for carrying out the same. To this end, a microfluidic channel having well structures is formed, and a cell solution containing cells is then introduced into the fluidic channel. Thereafter, the cell solution recedes in the microfluidic channel, thus providing a method of arraying cells in the well structures at a single-cell level, a method of analyzing cells using the same, and a cell analysis chip used for carrying out the same. With only very small amount of samples, it is possible to arraying the cells at a single-cell level very simply and economically without an additional apparatus or power. Accordingly, responsiveness such as response intensity of each cell upon an analysis reagent can be observed and the analysis can be made at a single-cell level. That is, it is possible to enhance the reliability of the cell analysis notably and improve the efficiency and accuracy of an individual cell analysis remarkably, so that these methods and cell analysis chip can be widely applied to the whole bio industries. | 2009-04-09 |
20090093375 | DNA or RNA detection and/or quantification using spectroscopic shifts or two or more optical cavities - A spectroscopic technique for high-sensitivity, label free DNA quantification uses a shift in an optical resonance (whispering gallery mode, WGM) excited in a micron-sized optical cavity (e.g., a silica sphere) to detect and measure nucleic acids. The surface of the silica sphere is chemically modified with oligonucleotides. Hybridization to the target DNA leads to a red-shift of the optical resonance wavelength. The sensitivity of this resonance technique is higher than most optical single-pass devices such as surface plasmon resonance biosensors. Each microsphere can be identified by its unique resonance wavelength. Specific, multiplexed DNA detection may be provided by using two or more microspheres. The multiplexed signal from two or more microspheres illustrates that a single nucleotide mismatch in an 11-mer oligonucleotide can be discriminated with a high signal-to-noise of 54. This all-photonic WGM biosensor can be integrated on a chip, such as a semiconductor chip, which makes it an easy to manufacture, analytic component for a portable, robust lab-on-a-chip device. | 2009-04-09 |
20090093376 | Cellular microarray and its microfabrication method - A cellular microarray is disclosed, which has a substrate, multiple first conductive lines, multiple second conductive lines, and multiple PIREs arranged on the surface of the substrate in an array. Each PIRE includes multiple first ring-shaped electrodes, and multiple second ring-shaped electrodes. The first ring-shaped electrodes, and the second ring-shaped electrodes are located on the surface of the substrate alternately in each PIRE. Moreover, the outermost ring-shaped electrodes of any two adjacent feather-shaped electrodes are different. The disclosed cellular microarray can adhere the cells rapidly and uniformly, increase the output of manufacturing, and reduce the cost for manufacturing and application. | 2009-04-09 |
20090093377 | Method of disrupting heme transport in nematodes and of modelling and evaluating eukaryotic heme transport - A method for treating helminthic infections in a mammal or plant which entails administering one or more compounds which are metal-ligand chelate compounds containing a metal and a tetrapyrrole compound or a porphyrin compound, to mammal or plant in need thereof. | 2009-04-09 |
20090093378 | Method for sequencing a polynucleotide template - The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which methods result in the sequential determination of nucleotide sequences in two distinct and separate regions of the polynucleotide template. | 2009-04-09 |
20090093379 | Spot Pin, Spot Device, Liquid Spotting Method, and Method of Manufacturing Unit for Biochemical Analysis - The present invention relates to a spot pin ( | 2009-04-09 |
20090093380 | Method of manufacturing polymer array by coating photosensitizer - Provided is a method of manufacturing a polymer array by photolithography in which a molecule containing a photolabile protecting group is reacted with a surface of a substrate, and then a photosensitizer is coated on the surface of the substrate together with a coating material and the resulting substrate is exposed to light to perform a photochemical reaction. Even by using conventional semiconductor equipment and compounds without separately fabricating light exposure equipment or synthesizing a compound, a polymer array may be effectively manufactured by photolithography with lower exposure energy (shorter period of time). | 2009-04-09 |
20090093381 | Solid phase electrochemical synthesis with controlled product cleavage - Methods for electrochemically synthesizing polymers are provided in which a cleavable linker is coupled to the surface of at least one electrode of an array of electrodes on a substrate and a polymer coupled to the cleavable linker is synthesized through a series of monomer addition cycles. Polymers that are synthesized include nucleic acids and peptides. Cleavable linkers include linkers that can be cleaved under conditions such as reducing, oxidizing, acidic, and or basic conditions. Additionally, provided are devices that comprise an array of individually addressable electrodes having surface-attached cleavable linker molecules. | 2009-04-09 |
20090093382 | Methods and Compositions for Pre-emptively Controlling Undesirable Water Production From Oil and Gas Wells` - A method for pre-emptively reducing the production of water in an oil and gas well is provided. In one embodiment, a drill-in fluid having a relative permeability modifier (RPM) capable of impeding the production of water is introduced into the wellbore during drilling operations. In a second embodiment, a completion fluid having a relative permeability modifier (RPM) capable of impeding the production of water is introduced into the wellbore during completion operations. The drill-in fluid or completion fluid may further include an organosilicon compound to increase flow resistance and extend the effective RPM permeability application range. | 2009-04-09 |
20090093383 | Compatibilized Polymer Processing Additives - The present invention relates to compositions and methods for improving the melt processing of polymeric materials, and more particularly to the use of compatibilized polymer processing additives to enhance the melt processing of polymeric matrices. | 2009-04-09 |
20090093384 | Lubricants That Decrease Micropitting for Industrial Gears - The invention relates to an industrial gear formulation containing a high TBN overbased detergent that results in decreasing micropitting for industrial gears. | 2009-04-09 |
20090093385 | Lubricating Oil Composition - A lubricating oil composition comprising oil of lubricating viscosity and an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent manufactured in the presence of an amine- or ester-based friction modifier. | 2009-04-09 |
20090093386 | Overbased Metal Sulphonate Detergent - An overbased metal sulphonate detergent having incorporated therein at least one friction modifier including at least one amine group. | 2009-04-09 |
20090093387 | Lubricating Oil Composition - A lubricating oil composition comprising a Group II basestock and a neutral or overbased metal hydrocarbyl-substituted hydroxybenzoate detergent having a basicity index of less than 2. | 2009-04-09 |
20090093388 | NOVEL ACYL GROUP-CONTAINING COMPOSITION - According to the present invention, a process is provided for producing an acyl group-containing composition that includes a step of reacting a long chain N-acyl acidic amino acid anhydride with one or more compounds which have, per molecule, m functional groups of one kind or more selected from the group consisting of hydroxyl, amino and thiol groups in an aqueous solvent and/or a mixed solvent of water and an organic solvent (reaction step). The process makes it possible to produce an acyl group-containing composition that is free from coloration under moderate conditions. | 2009-04-09 |
20090093389 | Anti-corrosion detergent compositions and use of same in cleaning dental and medical instruments - A novel method for cleaning dental and medical instruments is disclosed, in which a cleaning solution including a low-residue corrosion inhibitor is used not only in a wash stage of the cleaning cycle, but also in at least one subsequent rinse cycle, to optimize both cleaning and rust prevention. A novel cleaning solution particularly suited to this method has a neutral to alkaline pH and comprises in aqueous solution a low-foaming surfactant and a corrosion inhibitor selected from the group of C4-C16 alkyl pyrrolidones and C1-C18 alkylamines. | 2009-04-09 |
20090093390 | Thickened Methyl Ester Microemulsions for Cleaning Hard Surfaces - A hard surface cleaning composition, particularly useful for cleaning vertical or other surfaces where superior surface cling is important and preferably in the form of an oil-continuous microemulsion, comprising one or more primary solvents, one or more polar solvents, and one or more primary emulsifiers, one or more secondary emulsifiers, one or more co-surfactants, one or more thickeners, water, and, optionally, one or more auxiliary additives. | 2009-04-09 |
20090093391 | LIQUID WASHING COMPOSITIONS AND LIQUID CLEANING COMPOSITIONS - The present invention relates to substance mixtures comprising at least one complexing agent and at least one enzyme, and to the use thereof in liquid washing compositions and liquid cleaning compositions, said complexing agent having a complex formation constant for calcium of from 3 to 6 and said calcium-binding enzyme having a calcium binding capacity of at least 1 molar equivalent of calcium per molar equivalent of enzyme. | 2009-04-09 |
20090093392 | Detergent Compositions and Their Use - Use of a detergent composition comprising an amine oxide surfactant, at least one branched nonionic surfactant and at least one anionic component for enhancing particulate soil removal from a fabric washed in a wash liquor containing the detergent composition. | 2009-04-09 |
20090093393 | Methods For Selective Targeting - A selective targeting method is disclosed comprising contacting a library of ligands, particularly a peptide library, with an anti-target to allow the ligands to bind to the anti-target; separating the non-binding ligands from the anti-target bound ligands, contacting the non-binding anti-target ligands with a target allowing the unbound ligands to bind with the target to form a target-bound ligand complex; separating the target-bound ligand complex from ligands which do not bind to the target, and identifying the target-bound ligands on the target-bound ligand complex wherein the target-bound ligands have a K | 2009-04-09 |
20090093394 | Fabric Conditioning Compositions - A fabric softening composition comprising from 1 to 80% by weight of ester-linked quaternary ammonium fabric softening material comprising a quaternised mixture of mono- di- and tri-ester of alkanolamine in which the tri-ester content of said mixture is from 25 to 50% by weight of said mixture, wherein: (i) when the tri-ester content is from 25 to 30% by weight of said mixture the free amine content of the composition is less than 0.5% by weight on the weight of said mixture, (ii) when the tri-ester content is more than 30% by weight of said mixture the free amine content of the composition is less than 6% by weight based on the weight of said mixture, the composition containing less than 1% by weight of free fatty acid based on said mixture. | 2009-04-09 |
20090093395 | METHOD FOR DETERMINING PREDISPOSITION TO PULMONARY INFECTION - Provided herein are methods and materials for diagnosing a subject's predisposition for pulmonary infection in a CF subject by detecting a pulmonary infection genetic marker. Pulmonary infection markers have been identified in the IL-1 gene cluster and may be useful in predicting CF disease progression and assessing a CF subject's response to therapy. | 2009-04-09 |
20090093396 | DIAGNOSTICS AND THERAPEUTICS FOR RESTENOSIS - Methods and kits for determining whether a subject has or is predisposed to developing restenosis are provided. | 2009-04-09 |
20090093397 | PHASEOLUS VULGARIS EXTRACTS, THEIR USE, AND FORMULATIONS CONTAINING THEM - Extracts obtainable by extraction from | 2009-04-09 |
20090093398 | Use of Fibroblast Growth Factor Fragments - A discovery process beginning with an in vivo screening of proteins, peptides, natural products, classical medicinal compound or other substances. The administration of compounds to the animal can be either direct or indirect, such as by the administration and expression of cDNA-containing plasmids. Since the discovery process of the invention is based on a non-preconceived hypothesis and whole organism multi-organ analysis, a compound can be selected for testing in the absence of any biological selection criteria. The resulting organism-wide pattern of the gene expression changes in the transcriptome provides an overview of the activities at the molecular and organism-wide levels. The discovery process of the invention then integrates in vivo profiling and internal and external genomic databases to elucidate the function of unknown proteins, typically within few months. The invention further relates to medical uses of fibroblast growth factor 23 (FGF-23), FGF-23 fragments, FGF-23 C-terminal polypeptides, FGF-23 homologs and/or FGF-23 variants. | 2009-04-09 |
20090093399 | Glycopegylation methods and proteins/peptides produced by the methods - The invention includes methods and compositions for remodeling a peptide molecule, including the addition or deletion of one or more glycosyl groups to a peptide, and/or the addition of a modifying group to a peptide. | 2009-04-09 |
20090093400 | Truncated keratinocyte growth factor (KGF) having increased biological activity - The present invention relates to a keratinocyte growth factor fragment, KGF | 2009-04-09 |
20090093401 | CYSTATIN C AS AN ANTAGONIST OF TGF-BETA AND METHODS RELATED THERETO - Disclosed are Cystatin C (CysC) homologues, including CystC homologues that act as antagonists or inhibitors of transforming growth factor-β (TGF-β). Also disclosed are methods to identify CystC homologues that are antagonists or inhibitors of TGF-β and compositions and therapeutic methods using CystC and homologues thereof to regulate the activity of TGF-β, and TGF-β-mediated tumor malignancy and invasion and other TGF-β-mediated fibrotic or proliferative conditions and diseases. | 2009-04-09 |
20090093402 | Albumin Fusion Proteins - The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disorders or conditions using albumin fusion proteins of the invention. | 2009-04-09 |
20090093403 | SYSTEMS, METHODS AND COMPOSITIONS FOR OPTICAL STIMULATION OF TARGET CELLS - Stimulation of target cells using light, e.g., in vivo or in vitro, is implemented using a variety of methods and devices. One example involves a vector for delivering a light-activated NpHR-based molecule comprising a nucleic acid sequence that codes for light-activated NpHR-based molecule and a promoter. Either a high expression of the molecule manifests a toxicity level that is less than about 75%, or the light-activated NpHR-based proteins are expressed using at least two NpHR-based molecular variants. Each of the variants characterized in being useful for expressing a light-activated NpHR-based molecule that responds to light by producing an inhibitory current to dissuade depolarization of the neuron. Other aspects and embodiments are directed to systems, methods, kits, compositions of matter and molecules for ion pumps or for controlling inhibitory currents in a cell (e.g., in in vivo and in vitro environments). | 2009-04-09 |
20090093404 | ACCELERATED ANGIOGENESIS-INDUCING PROTEIN, COMPOSITIONS INDUCING ACCELERATED ANGIOGENESIS AND USES THEREOF - The present invention refers to an angiogenesis-inducing protein, a composition containing it and the uses of said protein. | 2009-04-09 |
20090093405 | Non-Natural Amino Acid Polypeptides Having Modified Immunogenicity - Non-naturally encoded amino acid polypeptides with modulated immunogenicity and uses thereof are provided. | 2009-04-09 |
20090093406 | Vegetable Protein Concentrate Having a Reduced Insoluble Dietary Fiber Content and Increase Amount of Soluble Dietary Fiber Content - This invention relates to a vegetable protein composition of matter derived from an alcohol washed vegetable protein material, comprising; having a decreased amount of insoluble dietary fiber content and an increased amount of soluble dietary fiber content relative to said original amount of insoluble dietary fiber and soluble dietary fiber in the alcohol washed vegetable protein material. | 2009-04-09 |
20090093407 | MATRIX-TARGETED FUSION POLYPEPTIDES FOR TISSUE REGENERATION AND WOUND HEALING - The present invention relates to compositions and methods for promoting tissue repair and regeneration. The invention provides a fusion polypeptide useful for targeting tissues for regeneration and methods of use therefore. | 2009-04-09 |
20090093408 | Protection of exendin-4 peptides through conjugation - A method for protecting a peptide from peptidase activity in vivo, the peptide being composed of between 2 and 50 amino acids and having a C-terminus and an N-terminus and a C-terminus amino acid and an N-terminus amino acid is described. In the first step of the method, the peptide is modified by attaching a react group to the C-terminus amino acid, to the N-terminus amino acid, or to an amino acid located between the N-terminus and the C-terminus, such that the modified peptide is capable of forming a covalent bond in vivo with a reactive functionality on a blood component. In the next step, a covalent bond is formed between the reactive group and a reactive functionality on a blood component to form a peptide-blood component conjugate, thereby protecting said peptide from peptidase activity. The final step of the method involves the analyzing of the stability of the peptide-blood component conjugate to assess the protection of the peptide from peptidase activity. | 2009-04-09 |
20090093409 | NEUROPROTECTIVE SYNERGY OF ERYTHROPOIETIN AND INSULIN-LIKE GROWTH FACTORS - The present invention provides a method of providing acute neuroprotection by inducing the erythropoietin (EPO) signaling pathway in neuronal cells close to or subsequent to the time of excitatory insult; and inducing an insulin-like growth factor (IGF) signaling pathway in the neuronal cells close to or subsequent to the time of excitatory insult, thereby producing a synergistic acute neuroprotective effect in the neuronal cells. The invention also provides a method of preventing or reducing the severity of a neurologic condition in a subject by administering to the subject EPO or an active fragment or analog thereof at a dose of at most 2000 U/kg; and administering to the subject an IGF or an active fragment or analog thereof, thereby providing neuroprotection and preventing or reducing the severity of the neurologic condition. Such a method can be used to prevent or reduce the severity of, for example, Alzheimer's disease, Parkinson's disease, Huntington's disease, epilepsy, amyotrophic lateral sclerosis, multiple sclerosis, a movement disorder, HIV-associated dementia, HIV-associated neuropathy, neuropathic pain, migraine, glaucoma, drug addiction, drug withdrawal, drug dependency, depression or anxiety. | 2009-04-09 |
20090093410 | Methods for Local Treatment with Factor VII - The present invention provides methods for the local treatment of bleeding in a subject and/or reducing unwanted effects associated with the systemic administration of thrombotic agents to a subject, by local administration of FVII to the subject. | 2009-04-09 |
20090093411 | Long-acting hormone and growth factor compositions and uses thereof - This invention provides VEGF-FSH compounds having increased serum half-lives relative to either native VEGF or FSH, in which both VEGF and FSH are biologically active. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject, as well as methods for increasing vascularization in a tissue, particularly in ovarian tissue. | 2009-04-09 |
20090093412 | METHODS FOR THE MODULATION OF NEOVASCULARIZATION AND/OR THE GROWTH OF COLLATERAL ARTERIES AND/OR OTHER ARTERIES FROM PREEXISTING ARTERIOLAR CONNECTIONS - Described is the modulation of the neovascularization and/or growth of collateral arteries and/or other arteries from preexisting arteriolar connections. Methods are provided for enhancing neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections comprising contacting organs, tissue or cells with a colony stimulating factor (CSF) or a nucleic acid molecule encoding said CSF. Furthermore, the use of a CSF or a nucleic acid molecule encoding said CSF for the preparation of pharmaceutical compositions for enhancing neovascularization and/or collateral growth of collateral arteries and/or other arteries from preexisting arteriolar connections is described. Also provided are methods for the treatment of tumors comprising contacting an organ, tissue or cells with an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through the inhibition of the biological activity of CSFs. Described is further the use of an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through inhibition of the biological activity of CSFs for the preparation of pharmaceutical compositions for the treatment of tumors. | 2009-04-09 |
20090093413 | METHODS FOR THE MODULATION OF NEOVASCULARIZATION AND/OR THE GROWTH OF COLLATERAL ARTERIES AND/OR OTHER ARTERIES FROM PREEXISTING ARTERIOLAR CONNECTIONS - Described is the modulation of the neovascularization and/or growth of collateral arteries and/or other arteries from preexisting arteriolar connections. Methods are provided for enhancing neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections comprising contacting organs, tissue or cells with a colony stimulating factor (CSF) or a nucleic acid molecule encoding said CSF. Furthermore, the use of a CSF or a nucleic acid molecule encoding said CSF for the preparation of pharmaceutical compositions for enhancing neovascularization and/or collateral growth of collateral arteries and/or other arteries from preexisting arteriolar connections is described. Also provided are methods for the treatment of tumors comprising contacting an organ, tissue or cells with an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through the inhibition of the biological activity of CSFs. Described is further the use of an agent which suppresses neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections through inhibition of the biological activity of CSFs for the preparation of pharmaceutical compositions for the treatment of tumors. | 2009-04-09 |
20090093414 | Hyaluronic Acid-Methotrexate Conjugate - An object of the present invention is to provide a hyaluronic acid-methotrexate conjugate useful as a therapeutic drug for joint disorders. There is provided a hyaluronic acid-methotrexate conjugate useful for the treatment of joint disorders, wherein methotrexate is conjugated with a hydroxy group of hyaluronic acid through a linker containing a peptide chain consisting of 1 to 8 amino acids, and the linker is conjugated with the hyaluronic acid through a carbamate group. | 2009-04-09 |
20090093415 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME - [Problem]To provide a therapeutic agent for irritable bowel syndrome (IBS), which is excellent in efficacy and safety. | 2009-04-09 |
20090093416 | CASPASE INHIBITORS AND USES THEREOF - The present invention provides a compound of formula I: | 2009-04-09 |
20090093417 | Dual-acting antihypertensive agents - The invention relates to compounds having the formula: | 2009-04-09 |