12th week of 2010 patent applcation highlights part 35 |
Patent application number | Title | Published |
20100076174 | ErbB Interface Peptidomimetics And Methods Of Use Thereof - Peptides, mimetics and antibodies of erbB, TNF, and IgSF receptors and pharmaceutical compositions comprising the same are described. Methods of using such antibodies, peptides, and mimetics in therapeutic, prophylactic, imaging and diagnostic applications are disclosed. | 2010-03-25 |
20100076175 | MOLECULES THAT SELECTIVELY HOME TO VASCULATURE OF PREMALIGNANT OR MALIGNANT LESIONS OF THE PANCREAS AND OTHER ORGANS - The invention provides a conjugate that includes a therapeutic moiety linked to a peptide or peptidomimetic that selectively homes to vasculature of premalignant pancreas. The peptide or peptidomimetic contains at least 5 contiguous amino acids of an amino acid sequence selected from CRSRKG (SEQ ID NO:9) and CEYQLDVE (SEQ ID NO:34), or a conservative variant or peptidomimetic thereof. The invention additionally provides a conjugate containing a therapeutic moiety linked to a peptide or peptidomimetic that selectively homes to pancreatic tumor cells and pancreatic tumor vasculature, the peptide or peptidomimetic comprising at least 5 contiguous amino acids of an amino acid sequence selected from CKAAKNK (SEQ ID NO:15), CKGAKAR (SEQ ID NO:19), and VGVGEWSV (SEQ ID NO:35), or a conservative variant or peptidomimetic thereof. | 2010-03-25 |
20100076176 | Sweetener Preparations and Methods of Use - The present disclosure relates to codon-optimized brazzein coding sequences and the expression of brazzein and variants thereof using yeast expression systems. The disclosure also relates to methods of expression of proteins to enhance the sweetness taste profile of foods and/or beverages. | 2010-03-25 |
20100076177 | Hybrid antibodies - Hybrid antibodies and/or hybrid antibody fragments and methods of making them are provided. In one embodiment the hybrid antibodies and/or hybrid antibody fragments contain heavy and/or light variable regions that contain two or more framework regions derived from at least two antibodies. In another embodiment, at least two of the framework regions are classified in the same germline gene family. In one embodiment, at least two framework regions are classified in the same germline gene family member. The hybrid antibodies or hybrid antibody fragments may contain human framework regions and nonhuman CDRs. | 2010-03-25 |
20100076178 | Dual Variable Domain Immumoglobulins and Uses Thereof - The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease. | 2010-03-25 |
20100076179 | ANTIBODIES TO MAMMALIAN CYTOKINE-LIKE FACTOR 7 - Novel mammalian zcyto7 polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods including antibodies and anti-idiotypic antibodies. | 2010-03-25 |
20100076180 | Method of fixing rail molecule and nano transport device - An object is to move a rail molecule by means of a biomolecular motor deposited on a base and inactivate the biomolecular motor through irradiation with light having a predetermined wavelength, to thereby readily and reliably fix the rail molecule at a predetermined position, while orienting the rail molecule in a predetermined direction without employment of any reagent. A method for fixing a rail molecule which has polarity and on which a biomolecular motor moves in a direction corresponding to the polarity includes depositing a biomolecular motor on a base; moving a rail molecule by means of the biomolecular motor; and inactivating the biomolecular motor by irradiating the biomolecular motor with light having a predetermined wavelength when the rail molecule reaches a predetermined position, to thereby fix the rail molecule so that it is oriented in a predetermined direction. | 2010-03-25 |
20100076181 | COMPOUNDS AND METHODS FOR LABELING OLIGONUCLEOTIDES - The invention provides a novel method of labeling oligonucleotides, with reporter moieties, including but not limited to, quenchers, fluorophores, biotin, digoxigenin, peptides and proteins. In addition, this invention provides a method of detecting hybridization of oligonucleotides. This invention also provides novel azo quenchers having the general formula shown below. | 2010-03-25 |
20100076182 | DISPERSION DYE, THE PRODUCTION AND USE THEREOF - The present invention provides dyes of the general formula (I) | 2010-03-25 |
20100076183 | PROTECTED MONOMER AND METHOD OF FINAL DEPROTECTION FOR RNA SYNTHESIS - A nucleoside monomer that is protected by a thionocarbamate protecting group is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that employs a diamine to deprotect a protected polynucleotide. | 2010-03-25 |
20100076184 | GBS TOXIN RECEPTOR - A novel GBS toxin receptor, and methods for its preparation and use are provided. GBS toxin receptor polynucleotides and polypeptides are provided as well as detection, screening, and therapeutic methods and pharmaceutical compositions involving such polynucleotides and polypeptides. | 2010-03-25 |
20100076185 | Selective Processing of Biological Material on a Microarray Substrate - The present invention provides methods and systems for selectively eluting biological material from a distinct spatial location on a microarray slide. In one aspect, for example, a method for recovering biological material coupled to a microarray slide can include selecting a biological material to be recovered from the microarray slide, finding the biological material within a distinct spatial region on the microarray slide surface, and eluting at least a portion of the selected biological material from the distinct spatial region without eluting substantial amounts of non-selected biological material from regions of the microarray slide that are not within the distinct spatial region. | 2010-03-25 |
20100076186 | PROCESS FOR PREPARING HETEROCYCLES - Provided is a process for preparing a heterocycle by catalytic reaction of an aromatic dinitrile with an amino alcohol, wherein the process includes: initially charging into a reaction vessel the amino alcohol and a catalyst to produce a reaction mixture; adding the aromatic dinitrile into the reaction mixture, which is maintained at a reaction temperature, wherein no solvent other than the amino alcohol of formula (III) is added to the reaction mixture prior to and/or during the catalytic reaction; and after completion of the catalytic reaction, completely replacing, or substantially completely replacing, unreacted amino alcohol with a nonpolar solvent to obtain the heterocycle, wherein the unreacted amino alcohol is present in an amount of not more than 20 wt. %, preferably 3-10 wt. % or less, based on a total weight of the heterocycle. | 2010-03-25 |
20100076187 | FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS - The present invention relates to 6-(piperidin-4-ylamino)pyridazin-3-carbonitriles that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects. | 2010-03-25 |
20100076188 | NOVEL CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE - Carboxylic acid derivatives | 2010-03-25 |
20100076189 | PROCESS FOR THE PREPARATION OF IMATINIB AND INTERMEDIATES THEREOF - It is the object of the present invention a process for the preparation of 4-methyl-N3-[4-(3-pyridinyl)-2-pyrimidinyl]-1,3-benzenediamine and analogues thereof, intermediates useful for the synthesis of Imatinib, or 4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide. | 2010-03-25 |
20100076190 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL - The problem to be solved by the present invention is to provide a highly-versatile method for producing a nitroxyl radical derivative, in which position-2 and position-6 in a TEMPO-based compound can be easily substituted, and further, a method for producing a nitroxyl radical derivative, in which a nitrogen nucleus is labeled with | 2010-03-25 |
20100076191 | PROCESS FOR PREPARING TRIAZOLE SUBSTITUTED AZAINDOLEOXOACETIC PIPERAZINE DERIVATIVES AND NOVEL SALT FORMS PRODUCED THEREIN - A process is provided for preparing triazole substituted azaindoleoxoacetic piperazine derivative. Novel intermediates produced in the above process, and novel N-1 and amorphous forms of a 1,2,3-triazole substituted azaindoloxoacetic piperazine derivatives and processes for producing such novel forms are also provided. | 2010-03-25 |
20100076192 | PROCESS FOR PRODUCING 5-METHYL-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-c]PYRIDINE-2-CARBOXYLIC ACID - 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine of formula (6) or a salt thereof, | 2010-03-25 |
20100076193 | PROCESS FOR THE PREPARATION OF GEMIFLOXACIN - The present invention relates to an improved process for the preparation of Gemifloxacin mesylate of formula (V). The present invention further provides novel intermediates of formula (II) and (IV), which are useful intermediates for the preparation of Gemifloxacin mesylate of formula (V). | 2010-03-25 |
20100076194 | SUBSTITUTED 3-AMINO-1-OXO OR THIOXO-1,2,5,6,7,8-HEXAHYDRO-2,7-NAPHTHYRIDINE-4-CARBONITRILES ARE SELECTIVE ALPHA 2B ANTAGONISTS - The present invention provides compounds which are subtype selective antagonists of the alpha 2B adrenergic receptor and have no or weak antagonist activity at the other alpha adrenergic receptors. These compounds are useful as tool compounds and, in particular, as tool compounds for developing compounds useful in treating diseases that include but are not limited to chronic pain, visceral pain, corneal pain, neuropathic pain, glaucoma, ischemic neuropathies and other neurodegenerative diseases and conditions. These compounds are also useful as compounds for treating myocardial infarction and preventing acute coronary events. The compounds of this invention are 3-amino-1-thioxo or oxo-1,2,5,6,7,8-hexahydro-2,7-naphthyridine-4-carbonitriles or substituted derivatives thereof. | 2010-03-25 |
20100076195 | PURIFICATION OF MONTELUKAST - The present invention provides methods of purifying montelukast, a new isolated impurity of montelukast, method for its isolation, and method of using montelukast impurity as a reference marker and a reference standard. | 2010-03-25 |
20100076196 | PROCESS FOR THE PREPARATION OF ILOPERIDONE - A process for the preparation of crystalline 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]-3-methoxyphenyl]-ethanone (Iloperidone), which comprises the reaction between 3-[1-(3-chloropropyl)-4-piperidinyl]-6-fluoro-1,2-benzisoxazole and 3-methoxy-4-hydroxy-acetophenone. | 2010-03-25 |
20100076197 | PROCESS FOR RIMONABANT - The present invention provides an improved and commercially viable process for the preparation of rimonabant substantially free of amide impurity, namely 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl-4-methyl-pyrazole-3-carboxamide and its pharmaceutically acceptable acid addition salts thereof. Thus, for example, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl-4-methyl-pyrazole-3-carboxylic acid chloride is reacted with 1-aminopiperidine in the presence of a base and optionally a phase transfer catalyst is used such as tetra-butylammonium bromide in a biphasic reaction medium containing water and a water-immiscible solvent to obtain pure rimonabant. | 2010-03-25 |
20100076198 | Crystalline forms of Fentanyl Alkaloid - The present invention provides crystalline forms of fentanyl alkaloid and methods for preparing crystalline forms of fentanyl alkaloid. | 2010-03-25 |
20100076199 | PROCESS FOR THE PREPARATION OF SUBSTITUTED PYRIDONE CARBOXYLIC ACIDS - The present invention relates to methods for the preparation of pyridone carboxylic acids for use as intermediates in the preparation of various synthetic organic compounds. The pyridone carboxylic acids can for example be used as intermediates in the production of potent antitumor agents, antifungal agents, antiviral agents, psychotherapeutic agents or contrast imaging agents for MRI. | 2010-03-25 |
20100076200 | Purification of olmesartan medoxomil - The present invention provides a process for purifying olmesartan medoxomil. | 2010-03-25 |
20100076201 | Carbazole Derivative and Method for Producing the Same - To provide a method for producing a wide variety of carbazole derivatives which have a simple and uncomplicated process and in which variations in the yield, purity, etc. of a desired substance which are caused by an aryl group introduced is reduced as much as possible. A method for producing a carbazole derivative represented by General Formula (1) is provided, in which 9-[4-(10-phenyl-9-anthryl)phenyl]-9H-carbazole having an active site at the 3-position of the carbazole skeleton and an aromatic compound having an active site are coupled. | 2010-03-25 |
20100076202 | METHOD FOR PRODUCING PYRROLIDINE DERIVATIVE - The present invention provides an advantageous method for producing an intermediate which is useful for production of a compound which exhibits excellent VLA-4 inhibitory effect and safety. | 2010-03-25 |
20100076203 | Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation - The present invention provides with a process of preparing an optically active succinimide derivative, which is a key intermediate for production of ranirestat. A compound (3) is easily prepared by treating the derivative of succinic acid diester of the formula (2): | 2010-03-25 |
20100076204 | PROCESS FOR THE PREPARATION OF LEVETIRACETAM - The present invention relates to a process for the preparation of levetiracetam and, more particularly, to an improved process for the preparation of levetiracetam characterized by a crystallization-induced dynamic resolution of a diastereoisomeric mixture of an (±)-alpha-ethyl-2-oxo-1-pyrrolidine acetamide derivative. | 2010-03-25 |
20100076205 | DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL - A dye compound is described, which is expressed by formula (I): | 2010-03-25 |
20100076206 | PROCESS FOR PREPARING NEBIVOLOL - The present invention relates to a process for preparing Nebivolol and, more particularly, to an improved process for synthesizing enantiomerically enriched 6-fluoro chroman alcohol or epoxide derivatives of formula, wherein R and X is defined in the description; as useful intermediates in the preparation of Nebivolol. | 2010-03-25 |
20100076207 | Epoxidation catalyst - Titanium or vanadium zeolite catalysts are prepared by reacting a titanium or vanadium compound, a silicon source, a templating agent, and a hydrophobic hydrocarbon liquid polymer. The catalyst is useful in olefin epoxidation with hydrogen peroxide. | 2010-03-25 |
20100076208 | HYDRO-OXIDATION PROCESS USING A CATALYST PREPARED FROM A GOLD CLUSTER COMPLEX - A process and catalyst for the hydro-oxidation of an olefin having three or more carbon atoms, such as propylene, to form an olefin oxide, such as propylene oxide. The process involves contacting the olefin with oxygen in the presence of hydrogen and a hydro-oxidation catalyst under reaction conditions; the catalyst comprising gold nanoparticles deposited on a nanoporous titanium-containing support, prepared by depositing a gold-ligand cluster complex onto the support to form a catalyst precursor, and then heating and/or chemically treating the catalyst precursor to form the hydro-oxidation catalyst composition. The hydro-oxidation catalyst exhibits stabilized catalyst activity, enhanced lifetime, and improved hydrogen efficiency. | 2010-03-25 |
20100076209 | PEG-lipid conjugates for liposomes and drug delivery - New diacylglycerol-polyethylene glycol (DAG-PEG) conjugates are described. A variety of linkers between the PEG chain and glycerol backbone of the DAG-PEGs may be selected to optimize liposomal formulations of pharmaceuticals and cosmetics. | 2010-03-25 |
20100076210 | METHOD FOR PRODUCING A RUTHENIUM COMPLEX - Provided is a method for producing a ruthenium complex comprises the step of reacting a ruthenium compound represented by general formula (1): | 2010-03-25 |
20100076211 | FLUORINE-CONTAINING SURFACE TREATING AGENT AND AN ARTICLE SURFACE-TREATED THEREWITH - The purpose of the present invention is to provide a surface treating agent which provides a surface where stain does not easily adheres, does not stand out and is easily wiped off. | 2010-03-25 |
20100076212 | METHOD FOR THE PURIFICATION OF TRIORGANOPHOSPHITES BY TREATMENT WITH A BASIC ADDITIVE - The invention provides a method for separating one or more triorganophosphite components from a crude phosphite mixture containing acidic hydrolysis products, the method comprising:
| 2010-03-25 |
20100076213 | METHOD FOR PRODUCING A DIALKYL CARBONATE AND A DIOL - A method for producing a dialkyl carbonate and a diol, comprising: (a) effecting a transesterification reaction between a cyclic carbonate and an aliphatic monohydric alcohol in the presence of a transesterification catalyst, thereby obtaining a reaction mixture containing a product dialkyl carbonate and a product diol, (b) withdrawing a dialkyl carbonate-containing liquid from the reaction mixture, followed by separation of the dialkyl carbonate from the dialkyl carbonate-containing liquid, and (c) withdrawing a diol-containing liquid from the reaction mixture, followed by separation of the diol from the diol-containing liquid, wherein the cyclic carbonate contains a cyclic ether in an amount of from 0.1 to 3,000 ppm by weight, and the product dialkyl carbonate contains a carbonate ether of not more than 10,000 ppm by weight. | 2010-03-25 |
20100076214 | PROCESS FOR PREPARING CYANOHYDRINS AND THEIR USE IN THE PREPARATION OF ALKYL ESTERS OF METHACRYLIC ACID - The invention relates to a process for preparing acetone cyanohydrin and to a process for preparing alkyl methacrylates, in which an acetone cyanohydrin as can be prepared in accordance with the present invention is used. | 2010-03-25 |
20100076215 | Process for Producing Arylsulfur Pentafluorides - Novel processes for preparing arylsulfur pentafluorides are disclosed. Processes include reacting at least one aryl sulfur compound with a halogen and a fluoro salt to form an arylsulfur halotetrafluoride. The arylsulfur halotetrafluoride is reacted with a fluoride source to form a target arylsulfur pentafluoride. | 2010-03-25 |
20100076216 | LIQUID CRYSTAL COMPOUND, OPTICAL ELEMENT, POLARIZING PLATE, IMAGE DISPLAY APPARATUS, AND OPTICAL RECORDING MATERIAL - Provided are a liquid crystal compound which can exhibit liquid-crystalline phase even at low temperatures, is excellent in uniform application performance and compatibility with another component, and suppresses inclusion of a polymeric component other than the object component, and an optical element having little defects in appearance, a polarizing plate, an image display apparatus, and an optical recording material using the liquid crystal compound. The liquid crystal compound of the present invention includes two or more chemical structures Q each represented by a general formula (1). | 2010-03-25 |
20100076217 | ACYLOXYLATION CATALYST AND PROCESS FOR ITS PRODUCTION - An acyloxylation catalyst is obtained by loading (a) a first component containing at least one element of Groups 8, 9, 10 and 11 of the Periodic Table, (b) a second component containing an element which is at least one element of Groups 8, 9, 10 and 11 of the Periodic Table and which is different from the element of the first component, and (c) a third component containing an element which is a component that produces a precipitation-starting pH below the precipitation-starting pH of the first component and second component and which is different from the elements of the first component and second component, onto (d) a support. A catalyst is obtained that can be used to efficiently carry out acyloxylation for economical production of acyloxylated compounds. | 2010-03-25 |
20100076218 | METHOD FOR PRODUCING ISOCYANATES - The invention relates to a process for preparing isocyanates in the gas phase. | 2010-03-25 |
20100076219 | METHOD FOR PREPARATION OF 6-[3(1-ADAMANTYL) -4-METHOXYPHENYL]-2-NAPHTOIC ACID - A method for preparation of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid is disclosed based on “one pot” synthesis approach including a direct synthesis of boronic acid derivative from 2-(1-adamantyl)-4-bromoanisole and cycloboranes with a subsequent Suzuki-Miyaura coupling with 6-halonaphthenoates and basic hydrolysis of the reaction product in ethylene glycol or 1,2-propanediol. | 2010-03-25 |
20100076220 | NOVEL METAL ORGANIC FRAMEWORKS BASED ON ALUMINUM, IRON AND CHROMIUM - The present invention relates to a porous metal organic framework comprising a bidentate organic compound coordinated to a metal ion selected from the group of metals consisting of Al, Fe and Cr, with the bidentate organic compound being derived from a dicarboxylic acid, wherein the framework has a structure whose projection along has a pattern in which each side of a hexagon is bounded by a triangle. The present invention further relates to shaped bodies and a process for preparing the porous metal organic framework and its use. | 2010-03-25 |
20100076221 | PREPARATION OF SULFONIC ACID ANHYDRIDES - Sulfonic acid anhydrides, and more particularly triflic anhydride, are prepared by reacting a sulfonic acid or a mixture of two sulfonic acids with a reactant exhibiting acid pseudohalide tautomerism and containing at least one carbon atom which is involved in the tautomerism bearing two halogen atom substituents. | 2010-03-25 |
20100076222 | Systems and Methods for Integrated Ammonia-Urea Process - Methods for producing urea are provided. A method for producing urea can include exchanging heat from a syngas comprising hydrogen and carbon dioxide to a urea solution comprising urea and ammonium carbamate. The heat transferred can be sufficient to decompose at least a portion of the ammonium carbamate. In one or more embodiments, the syngas can be reacted with liquid ammonia to provide a carbon dioxide lean syngas and an ammonium carbamate solution. The ammonium carbamate solution can be heated to a temperature of about 180 C or more. At least a portion of the ammonium carbamate in the heated ammonium carbamate solution can be dehydrated to provide the urea solution. | 2010-03-25 |
20100076223 | METHOD FOR PRODUCING A BETA-ALKOXYPROPIONAMIDE - A method for producing a β-alkoxypropionamide shown by the following formula (I) including the step of reacting a β-alkoxypropionic acid ester with an amine in the presence of a basic catalyst or in the presence of a basic catalyst and a polyol: | 2010-03-25 |
20100076224 | NOVEL TRIHALOMETHIONINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING THE SAME - A compound represented by the formula (I) is used as an active ingredient in a medicament for treatment or prevention of infectious diseases caused by protozoa or bacterium. | 2010-03-25 |
20100076225 | Polymorphs of atomoxetine hydrochloride - The present invention provides novel crystalline polymorph forms of atomoxetine hydrochloride denominated Forms B and C and methods for their preparation, as well as methods for the preparation of Form A. The present invention provides pharmaceutical compositions that comprise atomoxetine hydrochloride Form B, Form C, or mixtures thereof that can be used to treat attention deficit/hyperactivity disorder. | 2010-03-25 |
20100076226 | Preparation of Dibutoxymethane - A process for the preparation of dibutoxymethane, in one embodiment from 50% formaldehyde, in a condensation reaction without the use of co-solvent. | 2010-03-25 |
20100076227 | FLUIDIZED CATALYTIC PROCESS FOR PRODUCTION OF DIMETHYL ETHER FROM METHANOL - The present invention provides a fluidized catalytic process for production of dimethyl ether from methanol, wherein said process is carried out in a reactor in which the catalyst is in a fluidized state. Said process comprises the following steps of (1) feeding the methanol feedstock via two or more locations selected from the bottom, lower part, middle part and upper part of the reactor, contacting with the catalyst for preparation of dimethyl ether by methanol dehydration, carrying out the reaction of preparing dimethyl ether by methanol dehydration to obtain the reaction stream, separating said reaction stream to obtain a coked catalyst and a crude product primarily containing the target product, i.e. dimethyl ether; (2) totally or partially feeding the coked catalyst obtained in step (1) into a regenerator in a continuous or batch manner for regeneration via coke-burning, the regenerated catalyst being directly recycled to step (1) after being totally or partially cooled. | 2010-03-25 |
20100076228 | METHODS FOR IMPROVING SYNGAS-TO-ALCOHOL CATALYST ACTIVITY AND SELECTIVITY - The invention herein provides methods of activating a catalyst composition. These methods include annealing a catalyst with an inert gas, under effective conditions, and then contacting the annealed catalyst with syngas to produce an activated catalyst. These steps can also be reversed. The activated catalysts can be employed to convert syngas into products, such as alcohols, with improved selectivities and yields. | 2010-03-25 |
20100076229 | Method for Producing Alkenylnitrobenzene Derivatives Unbranched in the 1'-Position - The present invention relates to a process for preparing alkenylnitrobenzenes and alkylanilines, which are of significance as intermediates for fungicidally active alkylanilides. | 2010-03-25 |
20100076230 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF NITROBENZENE - The invention relates to a continuous process for the manufacture of nitrobenzene. This process comprises the nitration of benzene with nitrating acid that contains at least 3.0 wt. % of nitric acid and at least 67.0 wt. % of sulfuric acid, in a reaction space in which the start temperature of the reaction is above 100.0° C. but below 102.0° C. In addition, this process requires that the benzene and the nitrating acid are dispersed in one another several times. | 2010-03-25 |
20100076231 | PROCESSES FOR PRODUCING 2,3,3,3-TETRAFLUOROPROPENE, A PROCESS FOR PRODUCING 1-CHLORO-2,3,3,3-PENTAFLUOROPROPANE AND AZEOTROPIC COMPOSITIONS OF 1-CHLORO-2,3,3,3-TETRAFLUOROPROPENE WITH HF - A process is disclosed for making CH | 2010-03-25 |
20100076232 | HYDROCARBON FUEL OIL FOR USE IN FUEL CELL SYSTEM - Hydrocarbon fuel oil with paraffins as the main constituent for use in fuel cell systems is provided having
| 2010-03-25 |
20100076233 | SYNTHESIS OF LIQUID FUELS FROM BIOMASS - Processes and reactor systems are provided for the conversion of oxygenated hydrocarbons to paraffins useful as liquid fuels. The process involves the conversion of water soluble oxygenated hydrocarbons to oxygenates, such as alcohols, furans, ketones, aldehydes, carboxylic acids, diols, triols, and/or other polyols, followed by the subsequent conversion of the oxygenates to paraffins by dehydration and alkylation. The oxygenated hydrocarbons may originate from any source, but are preferably derived from biomass. | 2010-03-25 |
20100076234 | ALKYLATION UNIT AND PROCESS RELATING THERETO - One exemplary embodiment can be an alkylation unit. The alkylation unit can include at least one alkylation reaction zone having an alkylation catalyst, at least one cooler communicating with the at least one alkylation reaction zone, a settler communicating with the at least one alkylation reaction zone and the at least one cooler, a fractionation zone receiving an effluent from the settler passing through a line, and a boot coupled to a substantially horizontal portion of the line. Generally, the boot receives an effluent portion rich in the alkylation catalyst. | 2010-03-25 |
20100076235 | Processes for Gasification of a Carbonaceous Feedstock - The present invention relates to processes for preparing gaseous products, and in particular, methane via the catalytic gasification of carbonaceous feedstocks in the presence of steam and an oxygen-rich gas stream. The processes comprise using at least one catalytic methanator to convert carbon monoxide and hydrogen in the gaseous products to methane and do not recycle carbon monoxide or hydrogen to the catalytic gasifier. | 2010-03-25 |
20100076236 | PROCESS FOR PRODUCING PARAFFINIC HYDROCARBONS - Process for producing paraffinic hydrocarbons, the process comprising the following steps: (a) contacting hydrogen and a feedstock comprising triglycerides, diglycerides, monoglycerides and/or fatty acids with a hydrogenation catalyst under hydro-deoxygenation conditions; and (b) contacting the whole effluent of step (a) with a hydroprocessing catalyst comprising sulphided Ni and sulphided W or Mo as hydrogenation components on a carrier comprising amorphous silica-alumina and/or a zeolitic compound under hydro-isomerisation conditions. | 2010-03-25 |
20100076237 | Alkylaromatics Production - A process for alkylation or transalkylation of an alkylatable aromatic compound having reactive impurities with an alkylating agent to produce a monoalkylated aromatic compound, comprising the steps of contacting at least a portion of said alkylatable aromatic compounds and said alkylating agent with a first molecular sieve catalyst in a guard bed under suitable conditions to remove said reactive impurities and form a first effluent comprising monoalkylated aromatic compound, unreacted alkylatable aromatic compounds and unreacted alkylating agent; contacting said first effluent with a second molecular sieve catalyst different from said first molecular sieve catalyst in said reaction zone under suitable alkylation or transalkylation conditions to produce additional said monoalkylated aromatic compounds; and maintaining said water content from about 1 wppm to about 10 wt. % based on the combined weight of said alkylatable aromatic compound and said alkylating agent in said reaction zone for the majority of the on-oil time. | 2010-03-25 |
20100076238 | Production of Fuel from Co-Processing Multiple Renewable Feedstocks - A process for producing a fuel or fuel blending component from co-processing at least two different classes of renewable feedstocks, is presented. One feedstock comprises glycerides and free fatty acids in feedstocks such as plant and animal oils while the other feedstock comprises biomass derived pyrolysis oil. The source of the animal or plant oil and the biomass may be the same renewable source. | 2010-03-25 |
20100076239 | ASYMMETRIC CYCLOPROPANATION OF ELECTRON-DEFICIENT OLEFINS WITH DIAZO REAGENTS - Cobalt-catalyzed asymmetric cyclopropanation of electron-deficient olefins. | 2010-03-25 |
20100076240 | Production of Olefins - A process for converting a hydrocarbon feedstock to provide an effluent containing light olefins, the process comprising passing a hydrocarbon feedstock, the feedstock containing at least 25 wt % C | 2010-03-25 |
20100076241 | PROCESS FOR THE ALKYLATION OF ISOBUTANE WITH DILUTE PROPYLENE - A process for alkylation of propylene, the process including: contacting a stream comprising propylene and propane with sulfuric acid in a first reaction zone under conditions to form propylene sulfate esters; contacting the propylene sulfate esters with isoparaffin and sulfuric acid in an alkylation reaction zone under conditions to react the propylene sulfate esters and the isoparaffin to form a reactor effluent comprising an acid phase and a hydrocarbon phase comprising unreacted isoparaffin and alkylate product; separating the hydrocarbon phase from the sulfuric acid; separating the hydrocarbon phase to form a fraction comprising unreacted isoparaffin and a fraction comprising the alkylate product. | 2010-03-25 |
20100076242 | METHOD OF PREPARING 1-METHYLCYCLOPROPENE AND APPLYING THE SAME TO PLANTS - Disclosed is a method for directly preparing in situ 1-methylcyclopropene which inhibits the action of ethylene of accelerating the ripening process of plants, which comprises reacting a predetermined 1-methylcyclopropene precursor represented by the following Formula 2 or 3 with a base or fluoride anion material, and applying the 1-methylcyclopropene to plants: | 2010-03-25 |
20100076243 | BINDERLESS ADSORBENTS WITH IMPROVED MASS TRANSFER PROPERTIES AND THEIR USE IN THE ADSORPTIVE SEPARATION OF PARA-XYLENE - Adsorbents and methods for the adsorptive separation of para-xylene from a mixture containing at least one other C | 2010-03-25 |
20100076244 | Pill catcher - A method for the exclusive and singular treatment of all pharmaceuticals and drugs in any form that have passed their effective date, or are no longer of use to the individual, by mixing the pharmaceuticals and drugs with a granular solidification agent and water to form a non hazardous slurry which will solidify the liquefied pharmaceuticals and drugs into a non hazardous, environmentally friendly mixture safe for disposal into normal solid trash receptacles and landfills, and no longer a potential legal risk from ingestion after depositing into trash system. In this treatment the additional potential health risk and legal liability is eliminated from drugs and pharmaceuticals going into toilets and drains to sanitary sewers or septic tanks, and becoming liquid and untreatable at municipal wastewater treatment plants or septic fields, thereby returning to fresh water resources causing a risk to the general public health. | 2010-03-25 |
20100076245 | Pyromatic resource recovery system - A pyromatic system is used as a recovery system and is constructed to make the porylysis of used tires and other materials economically viable. The heart of the pyromatic system is a special stainless steel alloy reaction chamber which is mounted in a furnace box. The stainless steel alloy is known as Inconel. The reaction chamber is constructed of three tubular sections having flanges thereon. The flanges are finished to such close tolerances that no gasket are needed when the flanges are bolted together. The gaskets could not withstand the heat generated in the furnace box. Only the centrally located tubular sections is located in the furnace box. There is an auger rotating within the tubular reaction chamber to transport the shredded material there through while undergoing a pyrolisis. The auger is of the discontinuous type by heaving a multiple of cleats located in a helical pattern around a central shaft. This type of auger avoids a bunching of material while in transport and thereby eliminates hot spots in the tubular reaction chamber while maintaining an evenly distributed high temperature throughout its operation. | 2010-03-25 |
20100076246 | Intracorporeal Medicaments for High Energy Phototherapeutic Treatment of Disease - New intracorporeal radiodense medicaments and certain medical uses and methods for use of such high energy phototherapeutic medicaments for treatment of human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xanthene or halogenated xanthene derivative. The halogenated xanthenes constitute a family of potent radiosensitizers that become photoactivated upon irradiation of the treatment site with ionizing radiation. In embodiments of the present invention, such medicaments are used for treatment of a variety of conditions affecting the skin and related organs, the mouth and digestive tract and related organs, the urinary and reproductive tracts and related organs, the respiratory tract and related organs, the circulatory system and related organs, the head and neck, the endocrine and lymphoreticular systems and related organs, various other tissues, such as connective tissues and various tissue surfaces exposed during surgery, as well as various tissues exhibiting microbial or parasitic infection. In another embodiment, such medicaments are produced in various formulations including liquid, semisolid, solid or aerosol delivery vehicles. | 2010-03-25 |
20100076247 | PERMANENT VENTRICULAR ASSIST DEVICE FOR TREATING HEART FAILURE - The invention is a kit for a permanent ventricular assist device that can be permanently implanted into the circulatory system of a patient. The kit comprises one or more passive cores (Pcore), a stator, a power supply, and a controller unit. The inventors have realized that major open heart surgery, generally used for implementing a magnetic blood pump in the circulatory system, can be wholly avoided if the rotor and the stator are physically separated and are implanted respectively inside and around the blood vessel at the location of interest. Therefore the kit is characterized in that the one or more Pcores are configured to allow them to be implanted inside a blood vessel and the stator is configure to enable it to be placed outside of the blood vessel surrounding the Pcores. Also described are illustrative medical procedures for implanting the components of the kit at different locations in the body. | 2010-03-25 |
20100076248 | Incubator - An incubator according to the present invention will be able to prevent accidents to the incubator itself or other devices, a doctor, a nurse or others causing external force even if the external force is applied to a canopy of a newborn chamber. An optical detector in a control mechanism detects application of external force to the canopy of the newborn chamber, and a signal output section in the control mechanism outputs a signal that renders a driving mechanism for lowering and raising the canopy non-operational when the application of external force is detected. Accordingly, even if external force is applied to the canopy by bump, contact, putting some object or others, the driving mechanism will not continue or start to lower or raise the canopy while the external force is applied to the canopy because the driving mechanism will be rendered non-operational. | 2010-03-25 |
20100076249 | Computational system and method for memory modification - Systems and methods are described relating to accepting an indication of a schedule for administration of a memory-dampening agent to an individual and presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the memory-dampening agent to an individual. | 2010-03-25 |
20100076250 | LIGHTING SYSTEM FOR ENERGY STIMULATION - This invention relates to a lighting system for stimulating a user's energy by emitting bluish wake-up light and tuning the bluish light towards a daytime-like white light. | 2010-03-25 |
20100076251 | PYRO/PIEZO SENSOR AND STIMULATOR - This document discusses, among other things, an apparatus and method for detecting respiration information of a patient and for providing a stimulation to the patient. A sleep sensor transducer includes a pyro/piezoelectric film. A first and second electrode can attach to the film to transmit the detected respiration information to a closed loop neuromodulator and to receive stimulation energy from the closed loop neuromodulator to provide the stimulation. | 2010-03-25 |
20100076252 | PYRO/PIEZO SENSOR AND STIMULATOR HYBRID CIRCUIT - This document discusses, among other things, an apparatus and method for receiving respiration information of a patient and for providing a stimulation to the patient using a hybrid circuit. The hybrid circuit includes a control input for receiving a control signal having a first and second state. A sense switch of the hybrid circuit can provide respiration information from a pyro/piezoelectric film sleep sensor and stimulator to a closed loop neuromodulator in response to the first state. A stimulation switch of the hybrid circuit can provide stimulation energy from the closed loop neuromodulator to the pyro/piezoelectric film sensor and stimulator in response to the second state. The hybrid circuit can couple to the pyro/piezoelectric film sensor and stimulator using a single wire pair. | 2010-03-25 |
20100076253 | GUIDE GLASSES - A sound and light machine (SLM) produces sound and light that pulses at brain wave frequencies. The SLM is programmed to induce a particular state of consciousness in a user. The SLM includes a left and a right light emitting diode (LED) ( | 2010-03-25 |
20100076254 | ELECTRICAL MUSCLE STIMULATION TO TREAT FECAL INCONTINENCE AND/OR PELVIC PROLAPSE - Surgical procedures, kits and implants for alleviating human urinary and fecal incontinence are disclosed. Electrical stimulation is provided at one or more locations or positions in relation to or within an anal sphincter muscle comprising an internal anal sphincter surrounding the anus, an external anal sphincter surrounding the internal anal sphincter, a levator ani coupled to the external anal sphincter and perineal floor muscles around the anal orifice to treat or control fecal incontinence. Stimulation electrodes are mounted to one of a mesh patch, a fecal sling or the cuff of an artificial anal sphincter. Tissue anchors may be provided to engage tissue to stabilize mesh patch(es) or the fecal sling. Rectal pressure is detected and employed in controlling delivery of electrical stimulation. | 2010-03-25 |
20100076255 | Method and apparatus for treating a prolapse related condition - The present invention provides a method and apparatus for treating a prolapse related condition. The apparatus includes an implantable stimulator arranged to be implanted within a patient. The stimulator provides a signal for stimulation of tissue in the pelvic region. | 2010-03-25 |
20100076256 | CARDIAC DISEASE TREATMENT AND DEVICE - A jacket of biological compatible material has an internal volume dimensioned for an apex of the heart to be inserted into the volume and for the jacket to be slipped over the heart. The jacket has a longitudinal dimension between upper and lower ends sufficient for the jacket to surround a lower portion of the heart with the jacket surrounding a valvular annulus of the heart and further surrounding the lower portion to cover at least the ventricular lower extremities of the heart. The jacket is adapted to be secured to the heart with the jacket surrounding at least the valvular annulus and the ventricular lower extremities. The jacket is adjustable on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain circumferential expansion of the heart beyond the maximum adjusted volume during diastole and to permit unimpeded contraction of the heart during systole. | 2010-03-25 |
20100076258 | CAPSULE MEDICAL APPARATUS AND METHOD OF MANUFACTURING CAPSULE MEDICAL APPARATUS - A capsule medical apparatus includes a plurality of rigid boards on which functional members are mounted; and a plurality of board-separation keeping units that sandwich the rigid boards to keep the rigid boards separated. | 2010-03-25 |
20100076259 | MEDICAL APPARATUS - A medical apparatus according to the present invention is a medical apparatus used in a state in which the medical apparatus is led into a body and fixed. The medical apparatus includes: a fixing section that fixes the medical apparatus on a body wall in the body; an image pickup section that picks up an image of a subject in the body and is provided pivotably around a first axis; and a holding section that includes the fixing section and holds the image pickup section pivotably around a second axis different from the first axis. Therefore, the medical apparatus can change a photographing range and a visual field direction as desired to photograph the subject by performing magnified observation and photographing the subject from different directions without using a zoom function in the state in which the medical apparatus is fixed in a limited space in the body. | 2010-03-25 |
20100076260 | Handle Assembly for Articulated Endoscopic Instruments - An endoscopic surgical instrument is provided and includes a handle assembly for operating the surgical instrument, an articulatable neck assembly supported on and extending from the handle assembly, and an end effector operatively supported on the neck assembly. The handle assembly includes a housing; a trigger operatively supported on the housing; at least one actuation shaft operatively connected to the trigger and extending from the housing, wherein an actuation of the trigger imparts axial translation to the actuation shaft; and at least one articulation cable operable from the housing. The end effector includes a pair of pivotably mounted, juxtaposed jaws, wherein the jaws are movable at least between an open position and a closed position, and wherein a distal end of an actuation shaft is operatively engaged with the pair of jaws to effectuate opening and closing of the jaws. | 2010-03-25 |
20100076261 | EXAMINATION DEVICE - A device for imaging a bladder, comprising an image sensor, an illumination source and a device orientation actuator. | 2010-03-25 |
20100076262 | ENDOSCOPE INSPECTION SYSTEM - An endoscope inspection system. An image-capturing device is disposed on an endoscope probe and is electrically connected to a signal conditioning unit. A differential electrode set includes an annular detecting electrode and a reference electrode. The annular detecting electrode surrounds the endoscope probe. The annular detecting electrode, reference electrode, and display are electrically connected to the signal conditioning unit. | 2010-03-25 |
20100076263 | ENDOSCOPE SYSTEM, IMAGE PICKUP SYSTEM AND IMAGE PROCESSING APPARATUS - An endoscope system includes: an endoscope for picking up an image in a body cavity by an image pickup apparatus provided in a distal end of an insertion portion; a position detecting apparatus for detecting, based on luminal information acquired by the image pickup apparatus, position information used for inserting the distal end of the insertion portion; a recording apparatus for recording, in a time-sequential manner, the position information detected by the position detecting apparatus; a determining apparatus for determining whether or not the detecting operation of the position information performed by the position detecting apparatus satisfies a set condition; and a direction calculating apparatus for, when the determination result shows that the set condition is not satisfied, reading out the position information recorded in the recording apparatus and outputting information on a direction in which the distal end of the insertion portion is to be inserted. | 2010-03-25 |
20100076264 | ROTATE-TO-ADVANCE CATHETERIZATION SYSTEM - A method for visualizing the interior of a bodily passageway comprising providing a system comprising a plurality of concentric telescoping shafts; visualization apparatus disposed within the telescoping shafts; and a helical thread disposed on the exterior of the telescoping shafts, the helical threads having a sufficient structural integrity and surface profile such that when the telescoping shafts are disposed in the passageway, rotation of the telescoping shafts induces a relative movement between the telescoping shafts and the passageway; wherein the telescoping shafts are configured to be selectively coupled together and de-coupled from one another; inserting the system into the passageway; rotating the telescoping shafts so as to draw the passageway onto the telescoping shafts in a pleating fashion; de-coupling the telescoping shafts; rotating the innermost telescoping shaft so as to draw the passageway onto the innermost telescoping shaft in a pleating fashion; and visualizing the interior of the passageway. | 2010-03-25 |
20100076265 | ENDOSCOPE FLEXIBLE SECTION AND ENDOSCOPE - There is provided an endoscope and an endoscope flexible section that can secure bending rigidity and have the resistance against high temperature-and-pressure steam during sterilization. The endoscope flexible section includes a spiral tube, a net-like tube, and an outer cover member. The spiral tube is formed by winding a belt-like member made of metal, in a spiral shape. The net-like tube is formed in an annular shape on the periphery of the spiral tube by braiding thin metal wires. The outer cover member is formed on the periphery of the net-like tube. In the outer cover member, a polyparaxylene resin layer is formed in a pattern on the periphery of a cover layer that covers the periphery of the net-like tube and is made of fluororubber. The polyparaxylene resin layer is a pattern of the plural rings that are disposed in a circumferential direction at predetermined intervals. | 2010-03-25 |
20100076266 | ARTICULATION JOINT FOR VIDEO ENDOSCOPE - A video endoscope system includes a reusable control cabinet and an endoscope that is connectable thereto. The endoscope may be used with a single patient and then disposed. The endoscope includes an illumination mechanism, an image sensor, and an elongate shaft having one or more lumens located therein. An articulation joint at the distal end of the endoscope allows the distal end to be oriented by the actuators in the control cabinet or actuators in a control handle of the endoscope. Fluidics, electrical, navigation, image, display and data entry controls are integrated into the system along with other accessories. | 2010-03-25 |
20100076267 | ENDOSCOPE HAVING FORCEPS CHANNEL - An endoscope of a transnasal type includes an elongated tube for entry in a patient's body. A steering mechanism is provided in the elongated tube and on a proximal side from a distal end thereof, and bendable for changing a direction of the distal end. A forceps channel is formed through the elongated tube, for passing a treatment device to advance through the distal end. A constituent component is inserted in the elongated tube, disposed outside the forceps channel, and having an uneven thickness uneven within the steering mechanism in a direction transverse to an axial direction of the elongated tube, for extending in a tube lumen within the elongated tube. Specifically, the constituent component includes an air/water supply channel, or is an optical fiber bundle. | 2010-03-25 |
20100076268 | ENDOSCOPE FOR OBLIQUE VIEWING - An endoscope for oblique viewing including an image pickup device, a front lens group having a positive refractive power, a prism disposed on the CCD side of the front lens group, and a rear lens group disposed on the CCD side of the prism and having a positive refractive power. | 2010-03-25 |
20100076269 | Systems and Methods for Treating Sinuses - Systems and methods for treating paranasal sinuses in a head of a patient include, for example, forming an opening through a canine fossa into a maxillary paranasal sinus and performing a procedure such as a balloon catheter dilation of the maxillary sinus ostium. In some embodiments, one or more procedures other than a balloon dilation procedure may be performed. In some embodiments, a combination of balloon dilation and one or more other procedures may be performed. Various approaches involve employing medical devices to accomplish alternative treatment modalities as well as taking alternative routes to the interventional site. | 2010-03-25 |
20100076270 | Device for Use in a Surgical Procedure on a Human Eye - Presented is a device for use in a surgical procedure on an eye. The device includes an elongated member that includes a first elongated portion, a second elongated portion, and hook portion. The first elongated portion includes a proximal end and a distal end. The second elongated portion includes a proximal end and a distal end. The proximal end of the second elongated portion is coupled to the distal end of the first elongated portion. The second elongated portion extends from the first elongated portion at an angle to the longitudinal axis of the first elongated portion. The hook portion includes a proximal end and a distal end. The proximal end of the hook portion is coupled to the distal end of the second elongated member. | 2010-03-25 |
20100076271 | SOFT TIP CANNULA AND METHODS FOR USE THEROF - A surgical device having a body portion that is gripped by a user, the body portion having a distal end equipped with a soft tip and the proximal end optionally connected to an external vacuum or gas/air source. The surgical device is particularly suitable for use in ophthalmic surgical procedures to remove fluid from the eye or introduce gas/air into the eye. The soft tip is fabricated to protect the delicate tissues if the eye and is further modified so as to enhance a user's visibility of the device in the surgical field. | 2010-03-25 |
20100076272 | INTRODUCED IN CUTANEOUS TRANSLUMINA APPARATUS - An apparatus ( | 2010-03-25 |
20100076273 | DETECTOR FOR STATE OF PERSON - An object of the present invention is to provide a human condition detecting apparatus for highly accurately detecting a human condition, without any burden. A human condition detecting apparatus of the present invention is characterized by comprising a first stimulus applying device | 2010-03-25 |
20100076274 | Human-Digital Media Interaction Tracking - A system for human-digital media interaction tracking. One example system includes a database that stores information regarding a user's activity history for various different cognitive tasks, and a computing device that receives user behavior information indicating usage by a user of an interactive software program, the interactive software program associated with at least one of the cognitive tasks. The computing device, in response to the receipt of user behavior information indicating usage by the user of the interactive software program, updates the database information regarding the user's activity history for the at least one of the cognitive tasks. | 2010-03-25 |