11th week of 2011 patent applcation highlights part 47 |
Patent application number | Title | Published |
20110065879 | Non-Ionic Water-Soluble Additives Based on Allyl Ether and Vinyl Ether - The invention relates to a copolymer that can be obtained by the polymerization of the monomers (A), (B) and (C), (A) being a monomer of formula (I) wherein A is C | 2011-03-17 |
20110065880 | Ring-Opening Metathesis Polymerization Of Norbornene And Oxanorbornene Moieties And Uses Thereof - The present invention provides homopolymers resulting from ROMP of oxanorbornene dicarboxylic anhydride moieties and non-homopolymers resulting from ROMP of norbornene dicarboxylic anhydrides and oxanorbornene dicarboxylic anhydrides with co-monomer moieties. The invention further provides hydrogenated homopolymers resulting from ROMP of oxanorbornene dicarboxylic anhydrides and hydrogenated non-homopolymers resulting from ROMP of norbornene dicarboxylic anhydrides and oxanorbornene dicarboxylic anhydrides with co-monomer moieties. The invention further provides a wide variety of compositions comprising the novel ROMP moieties. Some of the novel ROMP moiety structures are set out below, wherein R | 2011-03-17 |
20110065881 | ORGANIC SILICON COMPOUND AND MATERIAL FOR FORMING SILICA-BASED FINE PARTICLE - An organic silicon compound includes a specific alkoxyorganopolysiloxane portion, a portion including an alkoxysilane group, the portion being bonded to the polysiloxane portion, and a portion including a resin-compatible chain or a reactive functional group, the portion being bonded to the polysiloxane portion. | 2011-03-17 |
20110065882 | CARDANOL BASED DIMERS AND USES THEREFOR - Cardanol based dimers are provided. The cardanol dimers are formed by hydrosylylation with silanes. Cardanol based dimers may be further reacted to form epoxy curing agents and epoxies which can be used as anti-fouling coatings on ship hulls and marine structures. The cardanol dimers may also be used to produce friction particles or phenolic resins. Methods of synthesizing the cardanol based dimers, the epoxy curing agents and the epoxies are also provided. | 2011-03-17 |
20110065883 | CARDANOL BASED DIMERS AND USES THEREFOR - Cardanol based dimers are provided. The cardanol dimers are formed by hydrosylylation with silanes. Cardanol based dimers may be further reacted to form epoxy curing agents and epoxies which can be used as anti-fouling coatings on ship hulls and marine structures. The cardanol dimers may also be used to produce friction particles or phenolic resins. Methods of synthesizing the cardanol based dimers, the epoxy curing agents and the epoxies are also provided. | 2011-03-17 |
20110065884 | POLYMERIZATION CATALYST FOR POLYTHIOURETHANE OPTICAL MATERIAL, POLYMERIZABLE COMPOSITION CONTAINING THE SAME, POLYTHIOURETHANE RESIN OBTAINED FROM THE COMPOSITION, AND PROCESS FOR PRODUCING THE RESIN - By using an amine hydrochloride represented by the formula (1) as a catalyst, a polythiourethane resin which is suitably used for a transparent resin for optical use, can be obtained without using an organotin compound which has been conventionally used as a catalyst for polythiourethane resins and without being affected by the acidity of an additive: | 2011-03-17 |
20110065885 | POLYISOCYANURATE ELASTOMER AND A COMPOSITION FOR PRODUCING SAME - A polyisocyanurate elastomer is produced from a composition. The composition comprises an isocyanate-reactive component and an isocyanate component. The isocyanate-reactive component comprises a diol having at least one ether group and further comprises at least one catalyst. The isocyanate-reactive component of the composition is substantially free of polyols. The isocyanate component comprises diphenylmethane diisocyanate. A method of producing the isocyanurate elastomer comprises the steps of providing the isocyanate-reactive component, providing the isocyanate component, mixing the isocyanate-reactive component and the isocyanate component to produce a reaction intermediary, and curing the reaction intermediary. | 2011-03-17 |
20110065886 | PROCESS FOR PREPARING HYPERBRANCHED, DENDRITIC POLYURETHANES BY MEANS OF REACTIVE EXTRUSION - The present invention relates to a process for preparing hyperbranched, dendritic polyurethanes by means of reactive extrusion. | 2011-03-17 |
20110065887 | PROCESS FOR PRODUCING PENTAERYTHRITOL MERCAPTOCARBOXYLIC ACID ESTER, PENTAERYTHRITOL MERCAPTOCARBOXYLIC ACID ESTER OBTAINED BY THE SAME, AND USE THEREOF - A process for producing pentaerythritol mercaptocarboxylic ester by reacting pentaerythritol with a mercaptocarboxylic acid having a content of thioester formed by condensation of two molecules of the acid of 5% or below (in terms of area percentage) as determined by the high-performance liquid chromatography in the case of the total area of the mercaptocarboxylic acid and thioester formed by intermolecular condensation of the acid is taken as 100%. | 2011-03-17 |
20110065888 | METHOD AND APPARATUS FOR FABRICATING A FIBRE REINFORCED THERMOPLASTIC COMPOSITE STRUCTURE - A method of fabricating a fibre reinforced thermoplastic composite structure comprising: placing a first layer of fibre reinforced thermoplastic material on top of a second layer of fibre reinforced thermoplastic material; providing a local heating source and locally heating a portion of at least the upper layer of thermoplastic composite material; and providing an ultrasonic transducer and locally introducing ultrasonic energy waves to the heated portion of the thermoplastic material such that ultrasonic consolidation of the fibre reinforced thermoplastic occurs. | 2011-03-17 |
20110065889 | POLYETHER POLYMER AND PRODUCTION PROCESS THEREOF - A polyether polymer containing a defined polymerization unit (—R | 2011-03-17 |
20110065890 | CALCIUM PHOSPHATE/BIODEGRADABLE POLYMER HYBRID MATERIAL, METHOD FOR PRODUCING SAME AND IMPLANT USING THE HYBRID MATERIAL - The present invention provides a calcium phosphate/biodegradable polymer hybrid material with high strength prepared by complexing a calcium phosphate porous material and a biodegradable polymer having a average molecular weight of 50,000 to 500,000, an implant comprising the hybrid material, and a method for producing a calcium phosphate/biodegradable polymer hybrid material prepared by immersing the calcium phosphate porous material within a solution including a biodegradable polymer and performing an ultrasonic treatment or a suction treatment. | 2011-03-17 |
20110065891 | POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF - Polythioetherimides and a producing method thereof. The method is comprised of using monosubstituted phthalic anhydride isomer as raw material, reacting it with disubstituted amine to produce disubstituted phthalimide, allowing coupling reaction between the obtained phthalimide and an alkali metal sulfide or sulfur to produce polythioetherimides. | 2011-03-17 |
20110065892 | PROCESS FOR THE SYNTHESIS OF FLUORINATED ETHERS OF AROMATIC ACIDS - Fluorinated ethers of aromatic acids are produced from halogenated aromatic acids in a reaction mixture containing a copper (I) or copper (II) source and an amino acid ligand that coordinates to copper. The fluorinated ethers of aromatic acids made using the process described herein can be applied to, e.g., fibers, yarns, carpets, garments, films, molded parts, paper and cardboard, stone, and tile to impart soil, water and oil resistance. By incorporating the fluorinated ethers of aromatic acids, or diesters thereof, into polymer backbones, more lasting soil, water and oil resistance, as well as improved flame retardance, can be achieved. | 2011-03-17 |
20110065893 | HEAT-SHRINKABLE POLYESTER FILM - The present invention relates to a heat-shrinkable polyester film, which has a heat-shrinkage of 20% or more in both the longitudinal and transverse directions when treated with 80° C. water for 30 seconds and a bidirectional balance parameter in the range of 0.25 to 2.5 and exhibits an excellent properties in die-cutting and removing from a container such as a glass bottle for recycling by washing with hot water. | 2011-03-17 |
20110065894 | METHODS OF CONTROLLING MOLECULAR WEIGHT DISTRIBUTION OF POLYMERS AND COMPOSITIONS THEREOF - A catalyst, co-catalyst, and/or chain transfer agent is added at a time after initiation of an addition polymerization reaction to produce a polymer product with a widened molecular weight distribution relative to having all of the components in the original reaction mixture. The catalyst, co-catalyst, or chain transfer agent may be added discretely or continuously to the reaction to produce a product with a bimodal, trimodal, or other broadened molecular weight distribution. | 2011-03-17 |
20110065895 | FUSED RING COMPOUND, METHOD FOR PRODUCING THE SAME, POLYMER, ORGANIC THIN FILM CONTAINING THE COMPOUND AND/OR POLYMER, AND ORGANIC THIN FILM DEVICE AND ORGANIC THIN FILM TRANSISTOR EACH COMPRISING THE ORGANIC THIN FILM - An object of the present invention is to provide a fused ring compound which can show sufficient charge transport properties and also has excellent solubility in a solvent. The fused ring compound of the present invention is represented by the following formula (1): | 2011-03-17 |
20110065896 | POLYETHER POLYOL DENDRON CONJUGATES WITH EFFECTOR MOLECULES FOR BIOLOGICAL TARGETING - Subject of the present invention are polyether polyol dendron conjugates comprising a specific polyether polyol dendron moiety, at least one certain fluorescent effector molecule (E). Such polyether polyol dendron conjugates may be used for diagnostic and therapeutic purposes, whereby the optical properties of the at least one certain fluorescent effector molecule are enhanced due to the attachment to the polyether polyol dendron conjugate. | 2011-03-17 |
20110065897 | METHOD FOR ISOLATING POLYPEPTIDES - The present invention relates to a method for isolating and/or purifying at least one polypeptide from a polypeptide-containing sample, characterized in that the sample is contacted with a boron carbide support material at a pH which allows the binding of the polypeptide to the boron carbide support material. Such isolating can, for example, be used to remove polypeptides from a sample or else to purify and/or to concentrate polypeptides. A matrix comprising a boron carbide support material for purification of polypeptides is further disclosed according to the invention. | 2011-03-17 |
20110065898 | Immunosuppressant Target Proteins - The present invention relates to the discovery of novel proteins of mammalian origin which are immediate downstream targets for FKBP/rapamycin complexes. | 2011-03-17 |
20110065899 | ANTIBODY AGAINST RGD IN AMINO ACID SEQUENCE OF EXTRACELLULAR MATRIX PROTEIN AND PRODUCTION METHOD AND USE OF THE SAME - The present invention provides a monoclonal antibody which specifically recognizes RGD in the amino acid sequence of extracellular matrix proteins of a human and a mouse. By specifically inhibiting the RGD sequence-mediated adhesion, exertion of efficient effects on diseases such as inflammation, cancer, infectious disease, autoimmune diseases and osteoporosis and reduction in adverse effects can be expected at the same time. Therefore, better treatment methods can be provided to these diseases. | 2011-03-17 |
20110065900 | SEPARATION METHOD UTILIZING POLYALLYLAMINE LIGANDS - The present invention relates to a method for removing at least one negatively charged substance from an aqueous liquid by contacting the liquid with a separation matrix comprising a plurality of polyallylamine ligands, comprising binding said negatively charged substance to said ligands under conditions where the ionic strength of the aqueous liquid applied to the chromatography resin ≧0.25 M NaCl. | 2011-03-17 |
20110065901 | Methods For Purifying A Target Protein From One or More Impurities In A Sample - The present invention relates, at least in part, to improved methods of protein purification. In particular, the present invention relates, at least in part, to methods for purifying an Fc region containing protein from a composition comprising the Fc region containing protein and one or more impurities, where the methods eliminate the need for a holding tank and/or a buffer exchange step. | 2011-03-17 |
20110065902 | HIGH AFFINITY HUMAN ANTIBODIES TO PCSK9 - An human antibody or antigen-binding fragment of a human antibody that specifically binds and inhibits human proprotein convertase subtilisin/kexin type 9 (hPCSK9) characterized by the ability to reduce serum LDL cholesterol by 40-80% over a 24, 60 or 90 day period relative to predose levels, with little or no reduction in serum HDL cholesterol and/or with little or no measurable effect on liver function, as determined by ALT and AST measurements. | 2011-03-17 |
20110065903 | Chromatographic methods - The current invention comprises a method for the regeneration of a cation exchange chromatography column. | 2011-03-17 |
20110065904 | H3LMN COMPOUND USED AS RADIOACTIVE AGENT FOR TREATMENT OF LIVER CANCER AND MANUFACTURING METHOD THEREOF | 2011-03-17 |
20110065905 | Ligand and metal complex - A ligand of Formula (I) is provided: | 2011-03-17 |
20110065906 | COMPOSITIONS AND METHODS FOR RECOVERY OF NUCLEIC ACIDS OR PROTEINS FROM TISSUE SAMPLES FIXED IN CYTOLOGY MEDIA - The present invention provides compositions and methods for improving nucleic acid or protein recovery from fixed biological samples. | 2011-03-17 |
20110065907 | Methods and compositions for labeling nucleic acids - The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. In particular, the methods include a [3+2] cycloaddition between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent attached to a label. Such methods do not require fixation and denaturation and therefore can be applied to the labeling of nucleic acid polymers in living cells and in organisms. Also provided are methods for measuring cellular proliferation. In these methods, the amount of label incorporated into the DNA is measured as an indication of cellular proliferation. The methods of the invention can be used in a wide variety of applications including clinical diagnosis of diseases and disorders in which cellular proliferation is involved, toxicity assays, and as a tool for the study of chromosomes' ultrastructures. | 2011-03-17 |
20110065908 | METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA - The invention provides compositions and methods for selectively reducing the expression of a gene product from a desired target gene, as well as treating diseases caused by expression of the gene. The method involves introducing into the environment of a cell an amount of a double-stranded RNA (dsRNA) such that a sufficient portion of the dsRNA can enter the cytoplasm of the cell to cause a reduction in the expression of the target gene. The dsRNA has a first oligonucleotide sequence that is between 26 and about 30 nucleotides in length and a second oligonucleotide sequence that anneals to the first sequence under biological conditions. In addition, a region of one of the sequences of the dsRNA having a sequence length of from about 19 to about 23 nucleotides is complementary to a nucleotide sequence of the RNA produced from the target gene. | 2011-03-17 |
20110065909 | SYNTHESIS OF OLIGONUCLEOTIDES - A method for preparing an oligonucleotide comprising the steps of | 2011-03-17 |
20110065910 | CARBOHYDRATES - Carbohydrates having functional groups, such as carboxylic acid groups and methods of making such carbohydrates. | 2011-03-17 |
20110065911 | METHOD FOR PRODUCING A BIOACTIVE GLUCAN PRODUCT SUBSTANTIALLY FREE OF ENDOTOXIN CONTAMINATION - The present invention relates to a method for producing a glucan product substantially free of endotoxin contamination. | 2011-03-17 |
20110065912 | NEW METHODS FOR THE PREPARATION OF TAXANES USING CHIRAL AUXILIARIES - A stereoselective synthesis of novel β-lactam dimers as useful precursors for the preparation of paclitaxel, docetaxel, and analogues thereof. More particularly, the new β-lactams are prepared from readily available and enantiomerically pure chiral auxiliaries. The β-lactams are then reacted with a suitably protected taxane to produce diastereomerically enriched side chain-bearing taxanes. Finally, the chiral auxiliary is cleaved and protecting groups are removed to provide the desired taxane. | 2011-03-17 |
20110065913 | PROCESS FOR PRODUCING LAUROLACTAM - The present invention relates to a process for producing laurolactam from cyclododecanone oxime by liquid-phase rearrangement reaction using trichlorotriazine as a rearrangement catalyst. The present invention can provide a process which can solve the problem of termination of the reaction at a certain conversion, can prevent an inactive precipitate generated from trichlorotriazine from precipitating in the course of the reaction process, and can remove an inactive precipitate, an active intermediate and a residual catalyst. | 2011-03-17 |
20110065914 | PERFLUORO MACROCYCLES IN 18F-LABELLING OF MACROMOLECULES - The invention relates to a synthetic strategy of using perfluoro crown ethers and other macrocycles to bind to [18F]-labelled fluorination reactions. The optional use of implementing perfluoro kryptofix 2.2.2 in this process is also disclosed. The present invention also claims perfluoro kryptofix structures that are suitable for use in 18F-labelling of fluorous based structures. | 2011-03-17 |
20110065915 | CATALYSTS FOR METATHESIS REACTIONS INCLUDING ENANTIOSELECTIVE OLEFIN METATHESIS, AND RELATED METHODS - The present invention provides compositions comprising metal complexes, and related methods. In some embodiments, metal complexes of the invention may be useful as catalysts for chemical reactions, including metathesis reactions, wherein the catalysts exhibit enhanced activity and stereoselectivity. In some embodiments, the invention may advantageously provide metal complexes comprising a stereogenic metal atom. Such metal complexes may be useful in enantioselective catalysis. | 2011-03-17 |
20110065916 | METHOD OF MAKING IMIDAZOAZEPINONE COMPOUNDS - A method of making a compound of Formula I: is carried out by (a) providing a compound of Formula (II) or (III): wherein ring A is C3-14 aryl or C3-14 heteroaryl such as phenyl or furanyl, and then (b) combining the compound of Formula (II) or (III) with an acid to produce a compound of Formula I. | 2011-03-17 |
20110065917 | PROCESS FOR THE PREPARATION OF OXCARBAZEPINE - The present invention relates to an improved process for the preparation of 10-oxo-10,11-dihydiO-5H-dibenz[b,fjazepine-5-carboxamide (Oxcarbazepine) by reacting 10-methoxy-5H-dibenz[b,f]azepine (10-methoxyiminostilbene) and alkali metal cyanate in presence of α-hydroxy acids, and also relates to the process for the preparation of carbamazepine from iminostilbene. Further the present invention is directed to the novel crystalline form of 10-methoxy carbamazepine. | 2011-03-17 |
20110065918 | NEW PHENYLALANINE DERIVATIVES - Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin. | 2011-03-17 |
20110065919 | 5-Substituted Indol-3-Carboxylic Acid Derivatives Exhibiting Antiviral Activity a Method for the Production and Use Thereof - The invention relates to novel antiviral compounds of general formula (I), where B is —N(R)2 or —O—(CH2)nN(R)2 groups, in which n is a whole number selected from 0, 1, 2, 3 and 4, each R is independently selected from C1-4 alkyl and can be identical or different, or both groups R together with a nitrogen atom, to which they are bonded, form a 5-6-membered heterocyclic ring containing 1-2 heteroatoms selected from nitrogen, oxygen and sulphur, such as pyrrolidine, piperidine, piperazine, morpholine or thyomorpholine, at which each of above-mentioned heterocyclic rings can be substituted by C1-4 alkyl, phenyl, benzyl, phenetyl, a carbonylamino —COOC1-4 alkyl group or the carbonylamino —COOC1-4 alkyl group and phenyl, which also can be substituted and have substituents selected from halogen, C1-4 alkyl, C1-4 alkoxy, and alkyl in said groups can be linear or branched; R1 is C1-4 alkoxy, phenyl optionally substituted by C1-4 alkyl or C1-4 alkoxy, halogen atoms, naphthyl; R2 is C1-4 alkyl, —S-phenyl, —S-benzyl, —O-phenyl, O-benzyl, wherein in each of the above-mentioned groups the phenyl ring is optionally substituted by C1-4 alkyl, C1-4 alkoxy, halogen atoms, or R2 is an —NR3R4 group, in which R3 and R4, each is independently selected from C1-4 alkyl and can be identical or different, or both R3 and R4 groups together with a nitrogen atom, to which they are bonded, form a 5-6-membered nitrogen-containing heterocyclic ring having the above mentioned value for the N(R)2 group; X is hydrogen or a halogen atom selected from Br, Cl, and I or pharmaceutically acceptable salts thereof. Intermediate products of general formula (II) and a method for producing the inventive compounds are also disclosed | 2011-03-17 |
20110065920 | PROCESS FOR PREPARING PENTANOIC DIACID DERIVATIVES - The present invention relates to a process for preparing pentanoic diacid derivatives useful for preparing pyrimidine derivatives, in particular as intermediates useful for preparing pyrimidine derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, such as HMG-CoA reductase inhibitors, e.g. rosuvastatin. | 2011-03-17 |
20110065921 | Organometallic Complex and Method for Producing the Same - An organometallic complex [Cu | 2011-03-17 |
20110065922 | Process for Preparation Of Solifenacin and/or the Pharmaceutically Acceptable Salts Thereof of High Pharmaceutical Purity - A process for the preparation of solifenacin and/or the pharmaceutically acceptable salts thereof of high pharmaceutical purity is characterized in that 3-(R)-quinuclidinoloxy anion generated in situ from 3-(R)-quinuclidinol in a presence of strong base in polar organic solvent is subject to acylation with (S)-1-phenyl-1,2,3,4-tetrahydroisoquinolinecarbonyl chloride of chemical purity at least 98%, while maintaining constant anion excess in a reaction mixture, and after reaction completion solifenacin base is optionally transformed into solifenacin salt according to standard procedures. (S)-1-Phenyl-1,2,3,4-tetrahydroisoquinolinecarbonyl chloride of chemical purity at least 98% is obtained in a reaction of (S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline and molar excess of phosgene in a presence of tertiary aromatic amine in aromatic hydrocarbon, and isolated in a crystalline form. | 2011-03-17 |
20110065923 | PROCESS FOR PRODUCTION OF CAREBASTINE - Processes are disclosed for preparing piperidine derivative compounds of the formulae I, II or III: | 2011-03-17 |
20110065924 | PREPARATION OF ASYMMETRIC ANTHRACENE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME - Provided is a method of preparing asymmetric anthracene derivative, more particularly, a method for high-yield production of an anthracene derivative in which an alkyl group, a cycloalkyl group, a heterocycloalkyl group, an aryl group or a heteroaryl group is introduced at position 2 of anthracene, and an aryl group or a heteroaryl group is introduced at each of positions 9 and 10 of the anthracene. | 2011-03-17 |
20110065925 | Process for the preparation of bidentate schiff base ruthenium catalysts containing a salicylaldimine-type ligand - The invention relates to a process for the preparation of bidentate Schiff base catalysts containing a salicylaldimine-type ligand. | 2011-03-17 |
20110065926 | METHOD OF PREPARING IONIC LIQUIDS - In the process for preparing ionic liquids, an ionic liquid is firstly reacted with an alkoxide or with barium hydroxide and is subsequently neutralized with an acid. The ionic liquid contains a phosphonium and/or ammonium cation and an anion selected from the group consisting of halides, arylsulfonates, alkylsulfonates, sulfate, hydroxysulfate, alkylsulfates, hydrogencarbonate, carbonate. triflate and carboxylates. In this process, virtually any anions can be introduced into the ionic liquids. | 2011-03-17 |
20110065927 | PROCESS FOR PREPARING PURE ANASTROZOLE - The present invention discloses two new related substances (6) and (7) of Anastrozole synthesis from Q.A. Salt (5) as in Scheme-1 and purification procedures to get Anastrozole (1) free from (6) and (7). | 2011-03-17 |
20110065928 | Process for Preparing Azabicyclic Compounds - The present invention relates to a process for preparing azabicyclic compounds that are useful intermediates for synthesizing pharmaceutical compounds or salts thereof. | 2011-03-17 |
20110065929 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST - Provide that a useful catalyst for homogeneous hydrogenation, particularly a catalyst for homogeneous asymmetric hydrogenation for hydrogenation, particularly asymmetric hydrogenation, which is obtainable with comparative ease and is excellent in economically and workability, and a process for producing a hydrogenated compound of an unsaturated compound, particularly an optically active compound using said catalyst with a high yield and optical purity. | 2011-03-17 |
20110065930 | PROCESS FOR THE SYNTHESIS OF (2S,3AR,7AS)-OCTAHYDRO-1H-INDOLE CARBOXYLIC ACID AS AN INTERMEDIATE FOR TRANDOLAPRIL - A process for the preparation of (2S,3aR,7aS)-octahydro-1H-indole-20carboxylic acid hydrochloride. | 2011-03-17 |
20110065931 | ATORVASTATIN CALCIUM PROPYLENE GLYCOL SOLVATES - Atorvastatin calcium propylene glycol solvates and processes to prepare these novel solvates which are particularly useful and suitable for pharmaceutical applications. | 2011-03-17 |
20110065932 | Process for the preparation of Levetiracetam - A process for the manufacturing of levetiracetam, wherein said process comprises the steps of: (1) reacting the (−)-(S)-alpha-ethyl-2-oxo-1-pyrrolidine acetic acid with a substoichiometric amount of an activating agent in an alcoholic solvent, and (2) subjecting the resulting reaction solution of step (1) to an ammonolysis process with gaseous ammonia. | 2011-03-17 |
20110065933 | PHOTOCHEMICAL PROCESS FOR PRODUCING ARTEMISININ - Provided is a new photochemical process for preparing artemisinin. Also provided are certain dihydroartemisinic acid derivatives useful for preparing artemisinin. | 2011-03-17 |
20110065934 | METHOD OF PRODUCING BICYCLO[3.1.0] HEXANE DERIVATIVE USING ENZYME - Production of a bicyclo[3.1.0]hexane derivative, useful as a metabotropic glutamate receptor modulator, becomes possible by a production method that includes converting a compound represented by Formula (II) into a compound represented by Formula (III) by reaction with an acyl group donor in the presence of a microorganism-derived enzyme, without using an expensive optically active trans hydroxy ester as a starting material and without employing a fluorination reaction requiring an ultralow temperature reaction. Furthermore, since asymmetric synthesis can be carried out in a stage closer to the final product, the production method is useful as a production method that can mass produce a bicyclo[3.1.0]hexane derivative. | 2011-03-17 |
20110065935 | INTERLOCKED MOLECULES AND RELATED COMPONENTS, COMPOSITIONS, MATERIALS, METHODS AND SYSTEMS - [c2] daisy chain macromers, dimers and polymers and related compositions, materials, methods and systems are described. | 2011-03-17 |
20110065936 | PROCESS FOR THE PREPARATION OF OLOPATADINE - The present invention relates to a novel process for the preparation of olopatadine hydrochloride starting from an advanced intermediate. | 2011-03-17 |
20110065937 | METHOD FOR THE SEPARATION OF INTERMEDIATES WHICH MAY BE USED FOR THE PREPARATION OF ESCITALOPRAM - The present invention relates to a novel method for the preparation of diol intermediates having the formula (II) and/or the opposite enantiomer of an acylated diol having the formula (IV) useful for the preparation of escitalopram involving selective enzymatic acylation or deacylation. | 2011-03-17 |
20110065938 | METHOD FOR THE PREPARATION OF ESCITALOPRAM - A novel method is provided for the manufacture of escitalopram. The method comprises chromatographic separation of the enantiomers of citalopram or an intermediate in the production of citalopram using a chiral stationary phase such as Chiralpak™ AD or Chiralcel™ OD. Novel chiral intermediates for the synthesis of Escitalopram made by said method are also provided. | 2011-03-17 |
20110065939 | METHOD FOR THE SEPARATION OF ACETONITRILE FROM WATER - A method for separating acetonitrile from water, comprising (i) providing a stream S1 containing at least 95 wt.-%, based on the total weight of S1, acetonitrile and water, wherein the weight ratio of acetonitrile:water is greater than 1; (ii) adding a stream P, comprising at least 95 wt.-% C3, based on the total weight of stream P, to S1 to obtain a mixed stream S2, C3 being propene optionally admixed with propane with a minimum weight ratio of propene:propane of 7:3; (iii) subjecting S2 to a temperature of 92° C. at most and a pressure of at least 10 bar, obtaining a first liquid phase L1 essentially consisting of C3, acetonitrile, and water, and a second liquid phase L2 essentially consisting of water and acetonitrile wherein the weight ratio of acetonitrile:water in L2 is less than 1; (iv) separating L1 from L2. | 2011-03-17 |
20110065940 | Method for the production of fat - The present invention relates to a method for the production of fat with a principal application as transportation biofuel or a component or raw material therefor. According to the method, cell masses, cell suspensions and/or liquid phases formed in the production of single cell oil, and/or biomass-containing side streams or microorganism cell masses for another purpose and/or originating from other sources, are contacted with a fat-production capable microorganism and the organism is allowed to produce fat. The resulting fat is recovered or the microorganism mass is passed to a single-cell oil production process. By means of the invention, the organic matter present in the cell mass and side streams of single-cell oil can be re-utilized for the production of the single-cell oil, thereby improving a total fat yield, as well as reducing an organic load of the side streams. | 2011-03-17 |
20110065941 | Plant body with modified program related to accumulation of storage material and the use thereof - The object of the invention is to provide a plant body in which the program for accumulating storage products has been modified, and applications of the same. In the invention, the plant body is constructed so as to have a B3 DNA-binding domain and an EAR motif, and so as to be capable of repressing the expression of two or more genes which code for two or more proteins having a sugar-inducible promotor function-suppressing activity. | 2011-03-17 |
20110065942 | PROCESS FOR PREPARING ESTERS OF ALCOHOLS AND GLYCERIN FROM TRIGLYCERIDES AND ALCOHOLS USING A HETEROGENEOUS CATALYST IN THE PRESENCE OF A CONTROLLED QUANTITY OF WATER - A process for preparing a composition of alcoholic esters of straight chain monocarboxylic acids containing 6 to 26 carbon atoms and glycerin, starting from a vegetable or animal oil, neutral or acidic, virgin or recycled with mono-alcohols containing 1 to 18 atoms, in the presence of a zinc aluminate catalyst and in the presence of a controlled quantity of water, can directly produce, in one or more steps, an ester which can be used as a propellant or fuel along with glycerin having improved purity containing a reduced quantity of ethers by using a partially dried catalyst. | 2011-03-17 |
20110065943 | Method for selective esterification of free fatty acids in triglycerides - A method for the selective esterification of free fatty acids, alone or in triglycerides, with C | 2011-03-17 |
20110065944 | NEW REACTIONS OF FULLERENES - A process for producing a fullerene derivative. The process comprises reacting a fullerene compound with a primary amine in the presence of a peroxide. | 2011-03-17 |
20110065945 | METHOD FOR PRODUCING LIQUID METAL CHELATE COMPOUND AND METAL CHELATE COMPOUND - The present invention is intended to provide a method for producing a liquid metal chelate compound which may be used as it is or diluted in water or the like, in a very simple procedure, in a short time, in a large quantity, and at a low cost, and to provide a metal chelate compound. | 2011-03-17 |
20110065946 | FLUORINATED NANODIAMOND AS A PRECURSOR FOR SOLID SUBSTRATE SURFACE COATING USING WET CHEMISTRY - The present invention is directed to nanodiamond (ND) surface coatings and methods of making same. Such coatings are formed by a covalent linkage of ND crystals to a particular surface via linker species. The methods described herein overcome many of the limitations of the prior art in that they can be performed with standard wet chemistry (i.e., solution-based) methods, thereby permitting low temperature processing. Additionally, such coatings can potentially be applied on a large scale and for coating large areas of a variety of different substrates. | 2011-03-17 |
20110065947 | CARDANOL BASED DIMERS AND USES THEREFOR - Cardanol based dimers are provided. The cardanol dimers are formed by hydrosylylation with silanes. Cardanol based dimers may be further reacted to form epoxy curing agents and epoxies which can be used as anti-fouling coatings on ship hulls and marine structures. The cardanol dimers may also be used to produce friction particles or phenolic resins. Methods of synthesizing the cardanol based dimers, the epoxy curing agents and the epoxies are also provided. | 2011-03-17 |
20110065948 | Nanosized Copper Catalyst Precursors For The Direct Synthesis Of Trialkoxysilanes - The present invention provides a process for using nanosized copper, nanosized copper oxides, nanosized copper chlorides, other nanosized copper salts, and mixtures thereof, as sources of catalytic copper in the Direct Synthesis of trialkoxysilanes of the formula HSi(OR) | 2011-03-17 |
20110065949 | COMPOUND FOR SOLID POLYMER ELECTROLYTE MEMBRANE - An unsaturated compound including a urethane bond in a main chain and a sulfonic acid group, a phosphoric acid group, an alkylsulfonic acid group, or an alkylphosphoric acid group on a benzene ring in a side chain is provided. In addition, a solid polymer electrolyte membrane containing a compound prepared by polymerizing the above-mentioned compound and an electrolyte membrane-electrode assembly including diffusion layers adhered on both surfaces of the electrolyte membrane are provided. Furthermore, a solid polymer fuel cell using the electrolyte membrane-electrode assembly is provided. | 2011-03-17 |
20110065950 | PALLADIUM CATALYST SYSTEM COMPRISING ZWITTERION AND/OR ACID-FUNCTIONALYZED IONIC LIQUID - The present invention concerns a catalyst system in particular a catalyst system comprising Palladium (Pd), a zwitterion and/or an acid-functionalized ionic liquid, and one or more phosphine ligands, wherein the Pd catalyst can be provided by a complex precursor, such as Pd(CH | 2011-03-17 |
20110065951 | METHOD FOR PRODUCING n-PROPYL ACETATE - Provided is a method for producing n-propyl acetate capable of suppressing the deterioration of a hydrogenation catalyst to such an extent that the catalyst can be industrially used, for example, in the case where n-propyl acetate is produced by performing a hydrogenation reaction in the presence of the hydrogenation catalyst using, as a raw material liquid, a liquid containing allyl acetate or the like which has been produced from propylene, oxygen and acetic acid and obtained using a purification process such as distillation. In such a method for producing n-propyl acetate, the concentration of a formyl group-containing compound (such as acrolein, propionaldehyde or 2-methylcrotonaldehyde) and the concentration of an acryloyloxy group-containing compound (such as acrylic acid or allyl acrylate) in the raw material liquid are respectively set to 100 ppm by mass or less. As a result, the deterioration of the hydrogenation catalyst can be suppressed to such an extent that the catalyst can be industrially used. | 2011-03-17 |
20110065952 | ARRANGEMENT AND METHOD FOR PRODUCING HIGH-PURITY CRYSTALS - An arrangement and a method for producing high-purity crystals, such as temperature-sensitive pharmaceutical agents, in a countercurrent crystallization process. The arrangement comprises a plurality of crystallizers, mother liquor lines, each of which has a shut-off valve, and crystallization product lines, each of which has a shut-off valve, so that a mother liquor flow can be generated which is directed from a crystallizer to the second-next crystallizer in the direction of decreasing purity, and a crystallization product flow can be generated which is directed from a to dissolved crystallization product that is about to crystallize to the next crystallizer in the direction of higher purity. | 2011-03-17 |
20110065953 | PROCESS FOR THE LONG-TERM OPERATION OF A HETEROGENEOUSLY CATALYZED PARTIAL GAS PHASE OXIDATION OF AN ORGANIC STARTING COMPOUND - A process for the long-term operation of a heterogeneously catalyzed partial gas phase oxidation of an organic starting compound, in which the reaction gas input mixture is partially oxidized over a fixed catalyst bed which is accommodated in two successive temperature zones A, B whose temperature is changed with increasing operating time such that the initially lower temperature increases and the difference between the two temperatures decreases. | 2011-03-17 |
20110065954 | Compound With Carboxyl Acid Group And Amide Group And Application Thereof - The present invention discloses compounds with a carboxyl acid group and an amide group which also containing the tertiary amino groups. The carboxyl acid group having a partial negative charge can attract the tertiary amino group with each other to form a quaternary ammonium salt structure, so that the compounds are easy to dissolve in water. Moreover, these compounds having a mushroom tyrosinase-inhibition effect and have the potential to use in the cosmetics for skin whitening. | 2011-03-17 |
20110065955 | Method For Preparing Difluoroacetic Acid and Salts Thereof - The invention relates to a method for preparing difluoroacetic acid and the salts thereof. The invention also relates to the preparation of difluoroacetyl fluoride used as an intermediate product in the preparation of difluoroacetic acid. The method for preparing difluoroacetic acid according to the invention is characterised in that the same comprises the step of preparing difluoroacetyl fluoride by reacting dichloroacetyl chloride with hydrofluoric acid in a gaseous phase and in the presence of a chromium-based catalyst, followed by the step of hydrolysing the difluoroacetyl fluoride thus obtained. | 2011-03-17 |
20110065956 | Method For Producing A Purified Borazine Compound, Method For Filling A Borazine Compound, And Container For Preserving A Borazine Compound - On producing a purified borazine compound, a borazine compound is filtrated under an atmospheric condition of a water content of not higher than 2000 volume ppm. Or, on filling a borazine compound into a container, the above described borazine compound is filled into the above described container under an atmospheric condition of a water content of not higher than 2000 volume ppm. Or, as a container for preservation for preserving a borazine compound, a container for preserving a borazine compound, which has withstanding pressure of not lower than 0.1 MPa, is used. | 2011-03-17 |
20110065957 | SYNTHESIS OF BIURETS AND ISOCYANATES WITH ALKOXYSILANE FUNCTIONS, FORMULATIONS CONTAINING SAME AND USE THEREOF - The invention relates to a composition and a method of preparing one such composition and an isocyanatoalkoxysilane; the polyisocyanate composition contains at least two different oligomeric compounds comprising at least three units and at most five units selected from aminoalkylsilane units and diamine units and at least one function selected from isocyanate functions and from those derived therefrom, the aforementioned compounds having at least two aminoalkylsilane units and another compound having at least two diamine units; the invention is suitable for coatings. | 2011-03-17 |
20110065958 | Low Temperature Curable Epoxy Compositions Containing Urea Curatives - A heat curable epoxy composition comprising the contact product of an epoxy resin, an epoxy curing agent and an accelerator for the epoxy curing agent, the curing agent or the accelerator comprising a urea compound which is the reaction product of an isocyanate and an alkylated polyalkylenepolyamine having one primary or secondary amine and at least two tertiary amines of the general formula: | 2011-03-17 |
20110065959 | Removal of Silica from Water Soluble Compounds by Nanofiltration and Reverse Phase Chromatography - A process for separating soluble silica species such as monomeric silicic acid (or monosilicic acid) and low molecular weight soluble polymeric silica from impure water soluble compounds by membrane nanofiltration is provided. A process for separating soluble silica species and colloidal silica from impure water soluble compounds by reverse phase liquid chromatography is also provided. | 2011-03-17 |
20110065960 | METHOD FOR PRODUCING DIPHENYLMETHANE DIAMINE - The invention relates to a process for preparing mixtures of diphenylmethanediamine and polyphenylenepolymethylenepolyamines, which comprises the steps | 2011-03-17 |
20110065961 | PROCESS FOR PRODUCTION OF PHOSPHINE DERIVATIVE FROM PHOSPHINE OXIDE DERIVATIVE - Disclosed is a process for producing a phosphine derivative from a phosphine oxide derivative, which comprises the following steps: (I) mixing a phosphine oxide derivative represented by formula (1) with a chlorinating agent in a polar organic solvent to cause the reaction between these components; and (II-1) adding a salt of a metal having an ionization tendency equal to or lower than that of aluminum to the reaction mixture and carrying out the reductive reaction in the presence of aluminum or (II-2) subjecting the reaction mixture to electrolytic reduction, thereby producing a phosphine derivative represented by formula (2). Ar | 2011-03-17 |
20110065962 | PROCESS FOR THE PREPARATION OF AROMATIC ALPHA-HYDROXY KETONES - Process for the preparation of aromatic alpha-hydroxyketones (aromatic α-hydroxyketones) that does not require the use of chlorine, sulfuryl chloride or bromine and comprises the halogenation of an intermediate aromatic ketone with a hydrogen halide in the presence of an oxidising compound. | 2011-03-17 |
20110065963 | PROCESS FOR PRODUCING DIMETHYL ETHER FROM METHANOL - Disclosed is a process for producing dimethyl ether from methanol, which is characterized in that the absorbing liquid used in said absorbing column is the bottom liquid of DME-fractionating column and/or bottom waste water of the methanol-recovering column. Said process can significantly reduce energy consumption of the apparatus. | 2011-03-17 |
20110065964 | Process For The Preparation Of Bronopol - The invention provides a process for preparing bronopol, which process comprises charging a reaction vessel with water, bromopicrin, nitromethane and paraformaldehyde, gradually feeding a base into said reaction vessel under stirring, bringing the reaction to completion and separating bronopol from the aqueous reaction mixture. | 2011-03-17 |
20110065965 | PROCESSES AND METHODS FOR EXTRACTION AND PURIFICATION OF LUTEIN FROM MARIGOLD ESTERS - A process is disclosed for simultaneously extracting, saponifying, and isolating lutein without the use of harmful organic solvents. In one embodiment the method includes (a) dispersing Marigold oleoresin in an alkane hydrocarbon alkanol solution, (b) adding a potassium hydroxide to the Marigold oleoresin and alkane hydrocarbon alkanol solution to form a homogenous solution of Marigold oleoresin, (c) refluxing the homogeneous solution until ester hydrolysis of the Marigold oleoresin is completed, (d) cooling the homogeneous solution and allowing it to settle until lutein crystals are formed and (e) washing the lutein crystals with methanol-hexane solution to separate and filter them from the solvents. | 2011-03-17 |
20110065966 | PROCESS AND PLANT FOR PRODUCING METHANOL - In the production of methanol from a synthesis gas containing hydrogen and carbon oxides, the synthesis gas is passed through a first, preferably water-cooled reactor, in which a part of the carbon oxides is catalytically converted to methanol. The obtained mixture containing synthesis gas and methanol vapor is supplied to a second, preferably gas-cooled reactor, in which a further part of the carbon oxides is converted to methanol. Subsequently, methanol is separated from the synthesis gas, and the synthesis gas is recirculated to the first reactor. To achieve a maximum methanol yield even with an aged catalyst, a partial stream of the synthesis gas is guided past the first reactor and introduced directly into the second reactor. | 2011-03-17 |
20110065967 | Preparation of Mannitol Modification III - Methods for preparing mannitol modification III are described herein. The methods relate to preparing solutions of mannitol in a suitable solvent and an auxiliary agent and solidifying from the solutions mannitol of modification III. | 2011-03-17 |
20110065968 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED BROMOBENZENES - The present invention relates to a process for the production of compounds of formula (I) wherein X is fluoro, chloro, bromo or iodo and n is 1, 2, 3 or 4, which process comprises reacting a compound of formula (II) wherein the substituents are as defined for formula (I), with inorganic nitrite in an acidic aqueous medium in the presence of bromide and a copper catalyst and wherein the process is carried out as a one-pot reaction. | 2011-03-17 |
20110065969 | METHOD AND SYSTEM FOR OXIDATIVELY INCREASING CETANE NUMBER OF HYDROCARBON FUEL - High energy (e.g., ultrasonic) mixing of a liquid hydrocarbon feedstock and reactants comprised of an oxidation source, catalyst and acid yields a diesel fuel product or additive having substantially increased cetane number. Ultrasonic mixing creates cavitation, which involves the formation and violent collapse of micron-sized bubbles, which greatly increases the reactivity of the reactants. This, in turn, substantially increases the cetane number compared to reactions carried out using conventional mixing processes, such as simple mechanical stirring. Alternatively, an aqueous mixture comprising water and acid can be pretreated with an oxidation source such as ozone and subjected to ultrasonic cavitation prior to reacting the pretreated mixture with a liquid hydrocarbon feedstock. | 2011-03-17 |
20110065970 | DIMERIZATION PROCESS - A process for the dimerization of isoolefins is disclosed. The process may include: contacting an isoolefin with sulfurous acid in a reaction zone at conditions of temperature and pressure sufficient to dimerize at least a portion of the isoolefin | 2011-03-17 |
20110065971 | Process for Cooling the Stream Leaving an Ethylbenzene Dehydrogenation Reactor - The present invention is a process for the production of styrene monomer from ethylbenzene comprising the steps of:
| 2011-03-17 |
20110065972 | Alkylaromatic Production Process - The present disclosure provides a process for selectively producing a desired monoalkylated aromatic compound comprising the step of contacting in a reaction zone an alkylatable aromatic compound with an alkylating agent in the presence of catalyst comprising a porous crystalline material under at least partial liquid phase conditions, said catalyst manufactured from extrudate to comprise catalytic particulate material of from about 125 microns to about 790 microns in size, having an Effectiveness Factor increased from about 25% to about 750% from that of the original extrudate, and having an external surface area to volume ratio of greater than about 79 cm | 2011-03-17 |
20110065973 | DOUBLE TRANSITION JOINT FOR THE JOINING OF CERAMICS TO METALS - The invention is directed to effective means for joining materials having dissimilar coefficients of thermal expansion, such as advanced ceramics with metallic compounds. Moreover, the present invention relates to furnace tubes and methods of fabricating a joint between two different materials, which is compositionally graded to provide a substantially graded coefficient of thermal expansion between the joint materials. | 2011-03-17 |
20110065974 | METHOD FOR DETERMINING AN IRRADIATION PLAN - A method for determining an irradiation plan includes specifying a target volume to be irradiated and a condition to be fulfilled, and implementing a first optimization. Implementing the first optimization includes providing a first data record, in which the target volume is mapped, and determining a first parameter set for the irradiation planning by implementing a first optimization algorithm. The first parameter set is optimized with respect to the condition to be fulfilled by using the first data record. The method also includes implementing a second optimization that includes providing a second data record that has a higher resolution than the first data record, determining a second parameter set by implementing a second optimization algorithm. The second parameter set is optimized with respect to the condition to be fulfilled by using the second data record and using the first parameter set. The method also includes generating an irradiation planning data record from the second parameter set. | 2011-03-17 |
20110065975 | Matrix applicator device and producing method thereof - A matrix applicator device for modulating biological organism electromagnetic field, includes a base having one or more surfaces, and one or more oscillating circuits for refracting electromagnetic waves of various ranges of the electromagnetic field into coherence form for the biological organism, comprising a plurality of closed loops intersectingly and symmetrically formed on the surface or under the surface of the base, wherein the closed loops are geometrically and/or physically distinguished from the base. | 2011-03-17 |
20110065976 | THERMALLY ASSISTED PULSED ELECTRO-MAGNETIC FIELD STIMULATION DEVICE AND METHOD FOR TREATMENT OF OSTEOARTHRITIS - A method, apparatus and a system for thermally-assisted pulsed electromagnetic field stimulation for treatment of osteoarthritis are disclosed. In one embodiment, the system comprises a multi-coil applicator adapted for positioning near or around of the treated joint, a pulse generator functionally coupled to the applicator, a power supply, and a feedback loop for stabilizing the temperature of the joint. The feedback loop includes a heating element, a temperature sensor and an electronic controller for maintaining the temperature of the joint in the range of 38 to 42 degree C. At elevated temperatures the healing effect of PEMF stimulation on the cartilage is maximized and overall efficiency of the treatment is improved. To produce a high electric field, the coils of the applicator are made with a low number of turns, for example less than 5 turns, and are spatially arranged to cover the whole joint without “dead” zones. | 2011-03-17 |
20110065977 | DISPOSABLE, SINGLE-USE THERMAL EXCHANGE COMPONENT - A disposable housing including a single-use thermal exchange component can be configured to be mechanically, removably coupled to a receptacle on a cuff positionable around a joint to provide temperature-based therapy to the joint. | 2011-03-17 |
20110065978 | Axial flow blood pump - An axial flow rotary blood pump including an impeller adapted to be magnetically rotated within a housing by the interaction of magnets disposed on or in the impeller and stators disposed on or in the housing. The impeller includes at least one support ring supporting a plurality of blades, and a hydrodynamic bearing that operates at least axially and radially in respect of an axis of rotation of the impeller. | 2011-03-17 |