10th week of 2010 patent applcation highlights part 40 |
Patent application number | Title | Published |
20100062412 | METHOD OF REMOVING ABNORMAL PRION PROTEIN FROM BLOOD PRODUCTS - Provided are a method of conveniently and efficiently removing abnormal prion protein from a blood product and a method of removing leukocyte simultaneously with abnormal prion protein. The method of removing an abnormal prion protein from a blood product includes filtering the blood product through a filter filled with a carrier coated with a polymer, which is composed of three units including 20 mol % or more and 40 mol % or less of a unit originating from a hydrophobic polymerizable monomer, 5 mol % or more and 13 mol % or less of a unit originating from a polymerizable monomer containing a basic nitrogen-containing part, and a unit originating from a polymerizable monomer containing a protonic neutral hydrophilic part as the balance, and then recovering the filtered blood product. | 2010-03-11 |
20100062413 | METHOD OF EVALUATING IBD, AMINO ACID DATA PROCESSOR, AMINO ACID DATA-PROCESSING METHOD, AMINO ACID DATA-PROCESSING SYSTEM, AMINO-ACID DATA-PROCESSING PROGRAM AND RECORDING MEDIUM - According to the method of evaluating IBD of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and an inflammatory bowel disease state in the subject is evaluated based on the measured amino acid concentration data of the subject. | 2010-03-11 |
20100062414 | SAMPLE LIQUID ANALYTICAL CHIP - A sample liquid analytical chip that whilst being of simple structure, has a reaction region and a detection region isolated from each other and further has liquid feed control means for a sample liquid, thereby realizing speedy reliable analysis. The sample liquid analytical chip comprises a tubular sample liquid transfer channel with its both ends open, a reaction reagent layer disposed on the internal wall surface of the sample liquid transfer channel and a detection region for detecting any physical or chemical change of the sample liquid. In the sample liquid analytical chip, the sample liquid transfer channel at an area of its wall surface is provided an opening and a lid fitted to the opening. Portion of the lid forms a hinge in cooperation with the wall surface. | 2010-03-11 |
20100062415 | Pathogen Detection Biosensor - The invention described herein provides methods for the detection of target particles, such as pathogens, soluble antigens, nucleic acids, toxins, chemicals, plant pathogens, blood borne pathogens, bacteria, viruses and the like. Also described is an emittor cell comprising a receptor, wherein the receptor can be an antibody or an Fc receptor, and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more receptors on the emittor cell. Also provided are optoelectronic sensor devices for detecting a target particle in a sample, including in a plurality of samples. | 2010-03-11 |
20100062416 | Immobilisation and application of antigenic carbohydrates to detect infective micro-organisms - The invention relates to the field of chemistry and diagnosis, more in particular to diagnosis of current and/or past and/or symptomless infections or of a history of exposure to a gram-negative-bacterium (such as an enterobacteriaceae or a | 2010-03-11 |
20100062417 | ZEOLITE CRYSTALS WITH BIOLOGICAL MATERIAL - The invention provides a hybrid construct comprising at least a zeolite crystal and at least one biological moiety such as for example a cells bacteria or virus and a method for the production thereof. | 2010-03-11 |
20100062418 | INACTIVATED AND DRIED BIOLOGICAL PREPARATIONS - In one aspect, the present invention provides biological sample that includes a dry preparation comprising a stabilizer and stabilized, inactivated biological material. In certain embodiments, the biological material may be heat inactivated and/or heat dried. In another aspect, the present invention provides a method of making a dried biological preparation. Generally, the method includes collecting a sample of biological material, inactivating the biological material, suspending the sample in a volume of a stabilizer and allowing the stabilizer to dry. In certain embodiments, the biological material may be heat inactivated and/or heat dried. | 2010-03-11 |
20100062419 | Infectious, Chimeric Hepatitis C Virus, Methods of Producing the Same and Methods of Use Thereof - The present invention provides infectious recombinant Hepatitis C Viruses (HCV), and vectors, cells and animals comprising the same. The present invention provides methods of producing infectious recombinant HCV, and their use in identifying anti-HCV therapeutic agents, as well as sequences of HCV associated with HCV pathogenesis. | 2010-03-11 |
20100062420 | Type I interferon-inducible proteins to detect viral infection - A method for determining the presence of a viral infection in an animal not known to have been infected with a virus or other disease-causing microbial organism by determining the level of Mx protein or other Type I Interferon-inducible protein in the animal. | 2010-03-11 |
20100062421 | COMPOSITIONS, METHODS, AND DEVICES FOR ISOLATING BIOLOGICAL MATERIALS - Compositions, methods, devices, and kits, which include an immobilized-metal support material comprising a substrate having a plurality of —C(O)O | 2010-03-11 |
20100062422 | Optical component for observing a nanometric sample, system comprising same, analysis method using same, and uses thereof - The invention concerns an optical component for observing a sample, which includes a substrate and at least one complex index layer of predetermined thickness, designed to show a high intensity or color contrast for optical path variations, reliefs, nanometric thicknesses and diameters when it is observed by incoherent light reflection convergent around the normal incidence under polarization extinction conditions. The upper index layer has specific surface properties providing it with selective affinity relative to at least one characteristic of the sample. An analysis system includes such a component, an analysis method using the component and uses of the method. | 2010-03-11 |
20100062423 | Fret Probes for Fluorescent Detection of the ESPS Gene - The present invention relates to a primer pair for the detection of a specific gene, and more particularly to a probe pair for the detection and analysis of an EPSPS (5-enolpyruvylshikimate-3-phosphate synthase) gene, in which primers complementary to the base sequences in the EPSPS gene are labeled with fluorophores acting as an energy donor and an energy acceptor, respectively. By introducing the inventive probe pair into cells, hybridizing the primers of the probe pair with the target gene and then analyzing the biological cells in a single cell unit using laser fluorescence measurement technique, cells containing the EPSPS gene of GMOs can be detected and the percentage of the GM cells in a cell mixture can also be quantified. | 2010-03-11 |
20100062424 | Assessment of Infectious Bacteria - Disclosed herein are methods for determining whether an opportunistic bacterium is infectious. | 2010-03-11 |
20100062425 | CAT ALLERGEN - The invention relates to a method for determining the level of Fel d1 expression in a cat, the method comprising: a) typing one or more polymorphic positions of the Fel d1 gene in a sample from the cat; and b) thereby determining the level of Fel d1 expression. | 2010-03-11 |
20100062426 | AGR2 and TFF3 Regulation in the Diagnosis and Treatment of Cancer - A method for assessing tumor progression is described by assessing AGR2 and/or TFF3 expression in a biological sample after induction of a physiological stress, such as hypoxia or serum deprivation in an enriched sample. Assessing the role of these indicators and their expression levels in an enriched CTC sample provides diagnostic and prognositic information on a patient. This method is also useful as a pharmatool in drug discovery. | 2010-03-11 |
20100062427 | METHOD FOR DETECTING DISEASE-ASSOCIATED MUTATIONS - A method is described for diagnosing individuals as having hypertrophic cardiomyopathy, e.g. familial or sporadic hypertrophic cardiomyopathy. The method provides a useful diagnostic tool which becomes particularly important when testing asymptomatic individuals suspected of having the disease. Symptomatic individuals have a much better chance of being diagnosed properly by a physician. Asymptomatic individuals from families having a history of familial hypertrophic cardiomyopathy may be selectively screened using the method of this invention allowing for a diagnosis prior to the appearance of any symptoms. Individuals having the mutation responsible for the disease may be counseled to take steps which hopefully would prolong their life, i.e. avoid rigorous exercise. The methodology used in the above method also has broad applicability and may be used to detect other disease-associated mutations in DNA obtained from subject being tested for other disease-associated mutations. | 2010-03-11 |
20100062428 | Methods for collecting and detecting oligonucleotides - Methods, pharmaceutical compositions, and kits are provided which includes accurately sampling a RNA from a tissue of an animal and analyzing RNA in the tissue of the animal as an indicator of physiological state, infectious disease, neoplastic disease, autoimmune disease, inflammatory disease, cardiovascular disease, atherosclerotic disease, or neurological disease in the animal. A method is provided which includes administering at least one compound to an animal wherein the at least one compound is configured to prevent the cleavage of at least one tissue RNA by a ribonuclease. The method further includes collecting a sample of at least a portion of tissue from the animal. | 2010-03-11 |
20100062429 | Fluorochromes for organelle tracing and multi-color imaging - Provided are compounds, methods and kits for identifying in cells of interest organelles including nuclei and a wide variety of organelles other than nuclei (non-nuclear organelles), as well as cell regions or cell domains. These compounds and methods can be used with other conventional detection reagents for identifying the location or position or quantity of organelles and even for distinguishing between organelles in cells of interest. | 2010-03-11 |
20100062430 | METHOD AND KIT FOR MOLECULAR CHROMOSOMAL QUANTIFICATION - Diagnosis of chromosomal abnormalities or genetic disorders is performed using at least two marker sequences, wherein one marker sequence is a sequence known to be present on the chromosome or in the gene of interest, another marker sequence is a sequence known to be present on an autosomal chromosome, and the marker sequences are partially homologous. A kit for performing this diagnosis is also claimed. | 2010-03-11 |
20100062431 | USE OF ADAMTS4 GENE AND PROTEIN POLYMORPHISMS - The use of the single nucleotide polymorphism (SNP) of the ADAMTS4 gene for the identification of cardiovascular and peripheral vascular disorders or of an increased risk for developing cardiovascular and peripheral vascular disorders in a biological sample taken from an individual to be examined; the use of ADAMTS4 for identifying substances active in preventing and/or treating cardiovascular and peripheral vascular disorders and methods for doing so. | 2010-03-11 |
20100062432 | METHOD OF DETECTING OR QUANTITATING ENDOGENOUS WHEAT DNA AND METHOD OF DETERMINING CONTAMINATION RATE OF GENETICALLY MODIFIED WHEAT IN TEST SAMPLE - An object of the present invention is to discover an endogenous wheat sequence satisfying the conditions of: a) it is universally present in varieties of wheat, b) the amount present (detected amount) is not affected depending on the wheat variety, c) even if other grains are present, only wheat can be detected without cross-reactivity, and d) it is amplified quantitatively by the PCR reaction. A further object of the present invention is to provide a method of accurately detecting and quantitating endogenous wheat DNA in a test sample by the polymerase chain reaction. The present invention provides a method of detecting or quantitating endogenous wheat DNA in a test sample by the polymerase chain reaction, the method comprising: a step of using a nucleic acid in the test sample or a nucleic acid extracted from the test sample as a template to amplify the nucleic acid of a region consisting of the base sequence identified as SEQ ID NO: 2 or a partial sequence thereof with a primer pair capable of amplifying that region; and a step of detecting or quantitating the amplified nucleic acid. | 2010-03-11 |
20100062433 | KIT FOR DETECTION/QUANTIFICATION OF ANALYTE, AND METHOD FOR DETECTION/QUANTIFICATION OF ANALYTE - Disclosed are a detection/quantification kit and a detection/quantification method for detecting/quantifying an analyte rapidly at a low cost and in a simple manner. Specifically, disclosed is a kit for detecting an analyte in a sample, comprising a first conjugate and a second conjugate, wherein the first conjugate comprises a first substance comprising a stimuli-responsive polymer and a first affinity substance having affinity for the analyte and bound to the first substance, and the second conjugate comprises a second substance carrying an electrical charge and a second affinity substance having affinity for the analyte and bound to the second substance. The first and second affinity substances can bind to different sites on the analyte simultaneously. | 2010-03-11 |
20100062434 | DETECTION OF CHROMOSOMAL INVERSIONS - A method and a kit for the identification of chromosomal inversions is described. Chromosomal inversions are difficult to detect unless they are quite large. The improved ability to detect chromosomal inversions is important to a number of medical applications, such as cancer and birth defects, as examples. Reporter species are attached to oligonucleotide strands designed such that they may hybridize to portions of only one of a pair of single-stranded sister chromatids prepared by the CO-FISH procedure, as an example. If an inversion has occurred, these marker probes will be detected on the sister chromatid at the same location as the inversion on the first chromatid. | 2010-03-11 |
20100062435 | Methods for Stem Cell Production and Therapy - The present invention relates to methods for rapidly expanding a stem cell population with or without culture supplements in simulated microgravity conditions. The present invention relates to methods for rapidly increasing the life span of stem cell populations without culture supplements in simulated microgravity conditions. The present invention also relates to methods for increasing the sensitivity of cancer stem cells to chemotherapeutic agents by culturing the cancer stem cells under microgravity conditions and in the presence of omega-3 fatty acids. The methods of the present invention can also be used to proliferate cancer cells by culturing them in the presence of omega-3 fatty acids. The present invention also relates to methods for testing the sensitivity of cancer cells and cancer stem cells to chemotherapeutic agents by culturing the cancer cells and cancer stem cells under microgravity conditions. The methods of the present invention can also be used to produce tissue for use in transplantation by culturing stem cells or cancer stem cells under microgravity conditions. The methods of the present invention can also be used to produce cellular factors and growth factors by culturing stem cells or cancer stem cells under microgravity conditions. The methods of the present invention can also be used to produce cellular factors and growth factors to promote differentiation of cancer stem cells under microgravity conditions. | 2010-03-11 |
20100062436 | Methods for Detection of a Single- or Double-Stranded Nucleic Acid Molecule - The present invention is related to a method for the detection of a nucleic acid molecule comprising at least a strand comprising a sequence of nucleotides in a sample, whereby the method comprises the following steps:
| 2010-03-11 |
20100062437 | PARALLEL PROFILLING OF SIGNALING PATHWAYS - Methods for identifying signaling pathways that regulate the expression of a test gene are provided. | 2010-03-11 |
20100062438 | NATURAL SELECTION AND CELLULAR IMMORTALITY - The invention provides new insights into the manner in which cells evolve and age thereby providing methods for assessing and studying those processes. | 2010-03-11 |
20100062439 | Method for Detecting Cyst Nematodes - The present invention relates to a method for determining the presence of a cyst nematode in a sample comprising the steps of : providing a pair of bidirectional oligonucleotide primers or an oligonucleotide probe that hybridizes specifically, under stringent hybridization conditions, to a nucleic acid sequence encoding the SSU rRNA or LSU rRNA, or the complement or transcript thereof, of a sub genus-cluster of nematodes, said subgenus-cluster comprising cyst nematodes belonging to at least one species of nematode, and wherein said primers or probe do not hybridize to a nucleic acid sequence encoding the LSU rRNA, or the complement or transcript thereof, of cyst nematodes not part of said subgenus-cluster of cyst nematodes; providing a sample in which the presence of the cyst nematode is to be detected, and performing a nucleic acid detection assay on said sample using said pair of bidirectional oligonucleotide primers or said oligonucleotide probe. | 2010-03-11 |
20100062440 | MARKERS FOR CANCER - The present invention relates to novel markers for hypermethylation of gene promoters in cancers. In particular the present invention relates to a method of determining whether a tumour is developing in the aero-digestive system, or whether a subject is relapsing after treatment of such a tumour. The method comprises determining the methylation level, the number of methylated CpG sites or the methylation state of CpG sites in a nucleic acid sequence in the promoter region, first exon or intron, of one or more genes selected from the group consisting of CNRIP1, MAL, FBN1, SPG20, SNCA, and INA. The method further relates to a diagnostic kit for detecting tumours in the aero-digestive tract. | 2010-03-11 |
20100062441 | C-MET MUTATIONS AND USES THEREOF - The present invention relates generally to the fields of molecular biology and growth factor regulation. More specifically, the invention concerns methods and compositions useful for diagnosing and treating human lung cancer associated with mutated c-Met. | 2010-03-11 |
20100062442 | CELL DETECTION - In one aspect the present invention provides a method of identifying a cell or cell colony which produces a polypeptide of interest, the method comprising exposing one or more cells to a marker compound which associates with a reference polypeptide, wherein production of the polypeptide of interest by the cells is linked to production of the reference polypeptide, and detecting association of the marker compound with the one or more cells, thereby identifying a cell or cell colony which produces the polypeptide of interest. | 2010-03-11 |
20100062443 | Methods for the Diagnosis and Treatment of Lung Cancer - The present invention provides methods for aiding in the diagnoses of the neoplastic condition of a lung cell and methods of screening for a potential therapeutic agent for the reversal of the neoplastic condition. | 2010-03-11 |
20100062444 | TLE3 AS A MARKER FOR CHEMOTHERAPY - Methods of using TLE3 as a marker for predicting the likelihood that a patient's cancer will respond to chemotherapy. Methods of using TLE3 as a marker for selecting a chemotherapy for a cancer. | 2010-03-11 |
20100062445 | Chromosome 1p36 polymorphisms and low bone mineral density - The invention provides methods and compositions for diagnosing risk of low BMD and risk of osteoporosis based on the detection of SNP identity for human chromosome 1p36 polymorphisms designated in the NCBI SNP database (dbSNP) as rs2794328, rs446529, rs397559 and rs1802353. | 2010-03-11 |
20100062446 | REACTOR PLATE AND REACTION PROCESSING METHOD - Disclosed herein is a reactor plate which prevents the entry of foreign matter from the outside and the pollution of an outside environment. The reactor plate includes sealed reaction wells ( | 2010-03-11 |
20100062447 | Methods for Identifying Cancer Risk - The present invention provides methods and kits for identifying an increased risk of developing cancer in a subject. The methods include analyzing a first biological sample, such as a blood sample, from the subject for loss of imprinting of the IGF2 gene. According to the methods a loss of imprinting is indicative of an increased risk of developing cancer. The method can include analyzing genomic DNA from the sample for altered methylation of the IGF2 gene. The altered methylation for example includes hypomethylation of a differentially methylated region of IGF2, corresponding to SEQ ID NO:1 or a polymorphism thereof. The method can be performed on a subject having no apparent or suspected hyperproliferative disorder such as cancer. | 2010-03-11 |
20100062448 | PROTEIN KINASE C ZETA AS A DRUG TARGET FOR ARTHRITIS AND OTHER INFLAMMATORY DISEASES - The present invention is based on the discovery that ζPKC expression is increased in the tissues of arthritis patients as compared to normal individuals. Accordingly, the present invention provides methods of diagnosing, prognosing, and monitoring the course of arthritis in a patient based on increased ζPKC gene expression in arthritic tissue. The present invention further provides compounds that inhibit the expression of ζPKC for use as remedies in the treatment of arthritis, including, but not limited to, inhibitory polynucleotides and polypeptides, small molecules, and peptide inhibitors. In addition, the present invention provides pharmaceutical formulations and routes of administration for such remedies, as well as methods for assessing their efficacy. | 2010-03-11 |
20100062449 | Method Of Measuring PTX3 With High Sensitivity - To provide a method of determining vasculopathy, which is a risk factor of myocardial infarction, angiopathic dementia, etc., at an early stage thereof (i.e., mild vasculopathy). The present invention provides a method of determining the severity of mild vasculopathy, including determining PTX3 level in an assay sample by use of an anti-PTX3 monoclonal antibody. | 2010-03-11 |
20100062450 | Methods and Kits for Early Detection of Cancer or Predisposition Thereto - Methods and kits for diagnosing cancer or a pre-malignant lesion by determining the presence and/or level of circulating CD24 of a subject are provided. Also provided are methods and kits for determining if a subject is predisposed to gastrointestinal cancer by the determining the presence or absence, in a homozygous or heterozygous form of cancer associated genotype(s) in the CD24 and/or APC nucleic acid sequences. Also provided are methods and kits for monitoring efficacy of cancer therapy by determining the presence and/or level of circulating CD24 of a subject. | 2010-03-11 |
20100062451 | Bead-ligand-nascent protein complexes - Bead-ligand-nascent protein complexes, and method of creating and detecting a bead-ligand-nascent protein complexes, are described. PCR-amplified product which is attached to a surface, e.g. of a bead, is used to generate nascent protein, which in turn is captured on the bead and detected, e.g. by fluorescence. | 2010-03-11 |
20100062452 | METHODS FOR DETERMINING SIGNAL TRANSDUCTION ACTIVITY IN TUMORS - The method of the invention pertains to determining the signal transduction activity in a tissue section by immunohistochemistry techniques. The expression level of the receptor of interest is determined as well as the expression levels of one or more effector molecules of the receptor signal transduction pathway. Furthermore a combined ratio of expression levels of effector molecules in subcellular compartments with the receptor expression was found to have prognostic significance. | 2010-03-11 |
20100062453 | Method of diagnosing endometriosis in human subjects - A method for diagnosing endometriosis in a human subject comprising the steps of detecting a test amount of an antibody that specifically binds to ME-5 (SEQ ID NO:3) polypeptide or a peptide comprising an epitope of ME-5 in a sample from the subject; and comparing the test amount with a normal range of the antibody in a control sample from a subject who does not suffer from endometriosis, whereby a test amount above the normal range provides a positive indication in the diagnosis of endometriosis. | 2010-03-11 |
20100062454 | Method for predicting risk of acquiring influenza - An object of the present invention is to provide a method for predicting the risk of acquiring influenza, which is characterized by low price, low invasiveness, and applicability to total automation. The present invention provides a method for predicting the risk of acquiring influenza, which comprises measuring the ratio of anti-influenza IgA to the total IgA in a specimen collected from a subject. | 2010-03-11 |
20100062455 | Rapid Detection of Cholinesterase Inhibitors - The present invention relates to a rapid, high-throughput detection method for screening of potential casualties exposed to a cholinesterase inhibitor. A kit is provided for conducting the method that requires only a small volume of sample such as blood for detection and has a rapid screening throughput for multiple casualties. The kit is able to detect both free and protein-bound-cholinesterase inhibitors. The method should be able to differentiate asymptomatic exposure from the mass psychogenic illness cases. | 2010-03-11 |
20100062456 | T2R, A NOVEL FAMILY OF TASTE RECEPTORS - The invention provides nucleic acid and amino acid sequences for a novel family of taste transduction G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste transduction G-protein coupled receptors. | 2010-03-11 |
20100062457 | BIOMARKERS, KITS, AND METHOD FOR DIAGNOSING, MONITORING, AND/OR STAGING ALZHEIMER'S DISEASE - The present invention is directed to a biomarker and kit for diagnosing, monitoring and/or staging Alzheimer's disease comprising redox-reactive autoantibodies. The present invention is also directed to a method for diagnosing, monitoring and/or staging Alzheimer's disease which comprises conducting a blood test using the same. | 2010-03-11 |
20100062458 | MONOCLONAL AND POLYCLONAL ANTIBODIES TO EQUINE ALBUMIN AND HEMOGLOBIN AND APPARATUS AND METHODS USING THE ANTIBODIES IN THE IDENTIFICATION AND LOCALIZATION OF ULCERS AND OTHER DIGESTIVE TRACT BLEEDING IN EQUINES - A diagnostic and testing apparatus and related methods for the use of the same are disclosed which derive and use antibodies to equine albumin and equine hemoglobin in testing apparatus, kits, and methods for detecting and localizing gastric and colonic ulcers or bleeding in horses. Fecal droppings from a horse to be tested are placed in a container together with a buffered liquid solution and mixed thoroughly, following which several drops of liquid from the container are placed into a test kit. Visual markers in the test kits signify the detection of the indicators equine hemoglobin and equine albumin, which are respectively indicative of the presence of gastric and/or colonic ulcers or bleeding. | 2010-03-11 |
20100062459 | Tacrolimus Standard and Methods of Using Same - A composition and kit useful as a tacrolimus standard solution for immunoassays, and methods for making and using same. The composition and kits include a known amount of tacrolimus or a derivative thereof, and a non-specific protein capable of forming a complex with the tacrolimus or derivative thereof. The standard solution may be used to generate calibration curves for an immunoassay or to check the precision of an analytical instrument. | 2010-03-11 |
20100062460 | Novel fluorochromes for organelle tracing and multi-color imaging - Provided are compounds, methods and kits for identifying in cells of interest organelles including nuclei and a wide variety of organelles other than nuclei (non-nuclear organelles), as well as cell regions or cell domains. These compounds and methods can be used with other conventional detection reagents for identifying the location or position or quantity of organelles and even for distinguishing between organelles in cells of interest. | 2010-03-11 |
20100062461 | MULTIPLEX DETECTION OF CELL SURFACE RECEPTORS OR IMMOBILIZED ANTIGENS - The present invention provides an antibody-based multiplex detection method for identifying one or more epitopes in one or more samples, the method comprising the steps of: (a) contacting each of the samples comprising the epitopes with one or more antibodies specific to the epitopes to be detected; (b) washing unbound antibodies away and eluting bound antibodies from the epitope carriers to provide separate antibody eluates; and (c) detecting and quantifying antibodies in the antibody eluates to generate separate profiles of antibodies for each of the samples. The epitopes to be detected can be located intracellularly, or present on the surface of cells or an artificial surface. In general, the epitopes are derived from protein, polypeptides with or without post-translational modification, carbohydrate, nucleic acid, or lipid. | 2010-03-11 |
20100062462 | IMMUNODEFICIENCY VIRUSES - This document relates to methods and materials involved in detecting, monitoring, and prognosing immunodeficiency virus infections. For example, methods and materials for determining whether or not a mammal (e.g., a human) has an immunodeficiency virus infection (e.g., an HIV infection), methods and materials for determining whether or not a mammal with an immunodeficiency virus infection is improving, and methods and materials for determining whether or not a mammal with an immunodeficiency virus infection has an advanced immunodeficiency virus infection are provided. | 2010-03-11 |
20100062463 | IN VITRO MULTIPARAMETER DETERMINATION METHOD FOR THE DIAGNOSIS AND EARLY DIAGNOSIS OF NEURODEGENERATIVE DISORDERS - In vitro multiparameter method for the diagnosis and early diagnosis, for determination of the severity and for assessing the course and prognosis of neurodegenerative disorders, in which the concentrations of at least two different vasotropic peptides are determined in a biological fluid from a person suffering from subjective or objectively detectable cognitive impairments, the resulting person-specific measurements are combined computationally to give a person-specific complex reference value, and conclusions are drawn concerning the presence of a neurodegenerative disorder in the person on the basis of the person-specific complex reference value found. | 2010-03-11 |
20100062464 | OXIDATIVE CHROMOGENIC COMPOUND OR SALT THEREOF AND PRODUCTION METHOD THEREOF, AND REAGENT COMPOSITION AND TEST INSTRUMENT USING THE SAME - It is an object of the present invention to provide a means for measuring a concentration of various components rapidly with high accuracy and high sensitivity. The present invention is to provide an oxidative chromogenic compound or salt thereof represented by the following chemical formula (1): | 2010-03-11 |
20100062465 | Detection of Histone Deacetylase Inhibition - Provided are compositions and methods for intracellular detection of enzyme activity. One example of a composition is a histone deacetylase substrate comprising a compound of the following formula (I): One example of a method is a method for detecting histone deacetylase activity comprising introducing a compound according to formula (1) to a plurality of cells and monitoring the cells with magnetic resonance spectroscopy. | 2010-03-11 |
20100062466 | MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA - A detection medium including
| 2010-03-11 |
20100062467 | Medium For Detecting And/Or Identifying Bacteria - The invention relates to a method for detecting and/or identifying | 2010-03-11 |
20100062468 | METHODS AND PRODUCTS RELATED TO LOW MOLECULAR WEIGHT HEPARIN - The invention relates to methods and products for characterizing and using polysaccharides. Low molecular weight heparin products and methods of use are described. Methods for characterizing purity and activity of polysaccharide preparations including glycosaminoglycans such as heparin are also described. | 2010-03-11 |
20100062469 | METHOD OF MEASURING 1,5-ANHYDROGLUCITOL IN WHOLE BLOOD, AND SENSOR CHIP AND MEASUREMENT KIT TO BE USED IN THE METHOD - By a method for measuring 1,5-anhydroglucitol, comprising the steps of: eliminating or converting glucose interfering with the measurement of 1,5-anhydroglucitol and/or a derivative thereof beforehand; and measuring 1,5-anhydroglucitol performed thereafter, wherein such glucose and/or a derivative thereof are/is eliminated or converted in whole blood as such without performing blood cell separation, an enzyme for measuring 1,5-anhydroglucitol is allowed to act on without performing blood cell separation, and 1,5-anhydroglucitol is electrochemically measured, it becomes possible to measure 1,5-anhydroglucitol using a small amount of whole blood without resort to a centrifuge or the like. Accordingly, this measurement method can be applied to rapid measurement of 1,5-anhydroglucitol at bedside or in a medical examination room or to home self-measurement thereof by a patient. | 2010-03-11 |
20100062470 | LUMINOGENIC COMPOUNDS AND METHODS TO DETECT CYTOCHROME P450 3A ENZYMES - Described herein are antibacterial compounds, methods for making the compounds, pharmaceutical compositions containing the compounds and methods of treating bacterial infections utilizing the compounds and pharmaceutical compositions. | 2010-03-11 |
20100062471 | Biomarkers for Multiple Sclerosis and Methods of Use Thereof - Biomarkers useful for identifying treatments for and monitoring treatment of patients with multiple sclerosis (MS) are provided, as well as methods for their identification, methods of diagnosing MS, relapse of MS patients and disease progression in MS patients. | 2010-03-11 |
20100062472 | BIOMARKERS FOR DIAGNOSING MULTIPLE SCLEROSIS, AND METHODS THEREOF - The present invention describes methods for the diagnosis and differential diagnosis of the different forms of multiple sclerosis The methods measure the intensities of specific small molecules called metabolites in samples from patients with clinically diagnosed relapsmg-remittmg or primary-progressive forms of multiple sclerosis and compare these intensities to the intensities observed in a population of healthy individuals, thus identifying markers of multiple sclerosis A method is also provided for the differential diagnosis of subjects afflicted with relapsing-renitting multiple sclerosis from secondary-progressive multiple sclerosis. | 2010-03-11 |
20100062473 | IMMUNITY EVALUATION METHOD, IMMUNITY EVALUATION APPARATUS, IMMUNITY EVALUATION PROGRAM AND DATA RECORDING MEDIUM HAVING THE IMMUNITY EVALUATION PROGRAM STORED THEREIN - An immunity evaluation method for evaluating immunity by using immune cell markers for immune cells contained in sampled blood comprises the step of determining an evaluation value for each of two or more selected kinds of immune cell markers based on the individual immune cell markers contained in the sampled blood, the step of adding the evaluation values so obtained for the at least two selected kinds of immune cell markers, and the step of evaluating the immunity from the results of the adding. | 2010-03-11 |
20100062474 | METHOD FOR THE PURIFICATION OF AT LEAST ONE TARGET SUBSTANCE THAT IS TO BE IDENTIFIED - Disclosed is a method for purifying at least one target substance that is to be identified and is present or is formed in a cell culture medium when cells are cultivated. In said method, magnetic particles, i.e. beads, to the functionalized surface of which the target substance selectively attaches, are added to the cell culture medium, and the particles to which the target substance is attached are selected out of the cell culture medium by applying a magnetic field. The method is characterized by the following steps: a serum substitute is provided that is obtained from a natural serum and is free or virtually free of low-molecular substances having a maximum mass of 60 kDa, particularly a maximum mass of 10 kDa; the serum substitute is admixed to the cell culture medium which already contains the cells or to which the cells are added; the cells are incubated in the cell culture medium enriched with serum substitute; at least some of the cell culture supernatant formed during the incubation is separated; the cell culture supernatant is filtered by means of an ultrafiltering process so as to obtain a retentate; the beads are supplied in such a way that the functionalized surface of the beads comprises a plurality of dendrimers containing up to 10 branches, i.e. ten generations, the terminal points of the last generation of each dendrimer being modified; the beads and the retentate are admixed to a buffer solution so as to obtain a mixture; the target substances contained in the retentate are incubated and are fixed to the beads; and the magnetic beads are magnetically selected out of the mixture. | 2010-03-11 |
20100062475 | PARTICLE FOR MEDICAL USE, PARTICLE FOR ANLAYSIS AND METHOD OF PRODUCING THE SAME - The object of the present invention is to provide a particle for medical use which has an excellent capability of fixing a biologically active substance and such a chemical/physical stability that the particle is less dissolved or deteriorated in a washing step, and a particle for analysis which has an excellent capability of capturing a biomolecule and such a chemical/physical stability that the particle is less dissolved or deteriorated in a washing step. | 2010-03-11 |
20100062476 | ASSESSING MAMMALS FOR VASCULAR DISEASES AND VALVULAR DISEASES - This document provides methods and materials related to assessing mammals for vascular disease. This document also provides methods and materials related to assessing mammals for valvular disease. For example, methods and materials for assessing mammals for vascular disease using elevated levels of endothelial progenitor cells expressing a bone-related polypeptide (e.g., an osteocalcin polypeptide) as markers are provided. | 2010-03-11 |
20100062477 | METHODS OF ISOLATING AND PROPAGATING STEM CELLS FROM BENIGN TUMORS - The present invention describes benign tumor stem cells, a method of isolating the benign tumor stem cells, a method of generating the benign tumor stem cells and a method of using the benign tumor stem cells. Uses of the benign tumor stem cells, such as pituitary stem cells include but are not limited to producing pituitary hormones and identifying drugs to treat pituitary disease conditions or pituitary-related disease conditions. | 2010-03-11 |
20100062478 | DRUG FOR ANALYSIS OF WATER TRANSPORT FUNCTION OF MEMBRANE PROTEIN IN BIOLOGICAL TISSUE - The present invention is to provide a drug for analysis of a water transport function of a membrane protein in a biological tissue, wherein the abundance of one or both of | 2010-03-11 |
20100062479 | METHOD AND DEVICE - A method of providing suspended cells ( | 2010-03-11 |
20100062480 | DEVICE, SYSTEM AND METHOD FOR STORING AND SORTING CELLULAR SAMPLES - The present invention discloses a sample sorter system adapted to receive and sort samples according to predetermined criteria. The sample sorter system comprises a receptacle that is adapted to receive and retain fluid and samples. The receptacle is operatively coupled with a drive and with a power source such that actuation of the drive causes the rotation of at least one circular component, which in turn causes the development of a flow regime in the receptacle such that the samples suspended in the fluid are conveyable along a closed path to at least one sample handling site that are positioned along said closed path. | 2010-03-11 |
20100062481 | Methods of Assaying Sensitivity of Cancer Stem Cells to Therapeutic Modalities - The present invention is directed to methods of measuring the proliferative ability of individual patient cancer stem cells. The present invention provides a method for treating a cancer patient according to an assay of the individual patient's tumor's cancer stem cell sensitivity, by measuring the proliferative ability of cancer stem cells from the patient. By the methods of the present invention it is possible to treat individual cancer stem cells presented in tumor cells. Methods of detecting and enumerating cancer stem cells in hybrid spheroids comprised of fibroblasts and tumor cells are also provided by the present invention. The present invention also contemplates a method for drug and other treatment development, wherein the effects of a drug or combination of drugs or other treatments are determined on the individual patient's cancer stem cells. | 2010-03-11 |
20100062482 | Fermentation Device Comprising a Coupled Substrate and Sediment Transport Mechanism and Method for Operating the Fermentation Device - A fermentation device for biological degradation of substrate containing organic material and for recovery of biogas produced by degradation has an elongate closed container having a first end and a second end opposite the first end. The first end has an inlet opening for untreated substrate and the second end has at least one removal opening for treated substrate. The container has at least one removal opening for biogas. The container has several reaction cells provided with individually driven mixing units. The mixing units have mixing unit shafts positioned transversely to a longitudinal extension of the container and mixing impellers mounted on the mixing unit shafts and driven on a circular path. The mixing unit shafts are arranged at axial spacings smaller than a diameter of the mixing units so that the mixing impellers when the mixing unit shafts rotate pass trough an overlap range. | 2010-03-11 |
20100062483 | PRODUCTION OF BIO-BASED MATERIALS USING PHOTOBIOREACTORS WITH BINARY CULTURES - A method, device and system for producing preselected products, (either finished products or preselected intermediary products) from biobased precursors or Co | 2010-03-11 |
20100062484 | Recombinant n-glycosylated proteins from procaryotic cells - The present invention relates to recombinant N-glycosylated proteins, comprising one or more introduced N-glycosylated optimized amino acid sequence(s), nucleic acids encoding these proteins as well as corresponding vectors and host cells. In addition, the present invention is directed to the use of said proteins, nucleic acids, vectors and host cells for preparing medicaments. Furthermore, the present invention provides methods for producing said proteins. | 2010-03-11 |
20100062485 | Novel Hansenula Polymorpha Gene Coding for Dolichyl-Phosphate- Mannose Dependent Alpha-1,3 Mannosyltransferase and Process for the Production of Recombinant Glycoproteins With Hansenula Polymorpha Mutant Strain Deficient in - The present invention relates to a process for producing a human-type glycoprotein having reduced glycosylation by genetically manipulating an enzyme involved in glycosylation using a | 2010-03-11 |
20100062486 | NOVEL PROTEIN AND DNA ENCODING THE PROTEIN - The present invention provides a protein comprising the amino acid sequence as shown in any one of SEQ ID NOS: 1 to 3 (except for proteins of the amino acid sequences as shown in SEQ ID NOS: 4 to 6), and a process for industrially advantageously producing a compound that inhibits HMG-CoA reductase and has an action to decrease serum cholesterol, using DNA encoding the protein comprising the amino acid sequence as shown in any one of SEQ ID NOS: 1 to 3 (except for DNA encoding the protein comprising the amino acid sequence as shown in SEQ ID NO: 4). | 2010-03-11 |
20100062487 | Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses - The invention provides isolated nucleic acids encoding a variety of proteins having diagnostic, preventive, therapeutic, and other uses. These nucleic and proteins are useful for diagnosis, prevention, and therapy of a number of human and other animal disorders. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening, and therapeutic methods using compositions of the invention are also provided. The nucleic acids and polypeptides of the present invention are useful as modulating agents in regulating a variety of cellular processes. | 2010-03-11 |
20100062488 | PREPARATION PROCESS OF RECOMBINANT HUMAN P43 PROTEIN - A process for producing human p43 protein is provided, in which the p43 protein can be used as a drug for treating solid tumor. | 2010-03-11 |
20100062489 | DUCK EMBRYONIC DERIVED STEM CELL LINES FOR THE PRODUCTION OF VIRAL VACCINES - The present invention relates to the development and manufacturing of viral vaccines. In particular, the invention relates to the field of industrial production of viral vectors and vaccines, more in particular to the use of avian embryonic stem cells, preferably the EBx® cell line derived from duck embryonic stem cells, for the production of viral vectors and viruses. The invention is particularly useful for the industrial production of viral vaccines to prevent viral infection of humans and animals. | 2010-03-11 |
20100062490 | Organic Compounds - The invention relates to a process for the recombinant production of a heterologous polypeptide of interest, comprising, (i) cultivation of a bacterial host cell which is transformed with an expression vector which comprises a nucleic acid molecule which codes for a fusion polypeptide, the fusion polypeptide comprising a derivative of an autoprotease N | 2010-03-11 |
20100062491 | Overexpression of the Chaperone BIP in a Heterokaryon - The present invention relates to a method for increasing the production yield of a secreted antibody or antibody fragment in a filamentous fungal host cell, comprising: recombinant expression of the antibody or antibody fragment and over-expressing a BiP chaperone protein. | 2010-03-11 |
20100062492 | Method For Preparing Icariside II, Cosmetic Composition Containing The Same and the Use Thereof For Skin Whitening - Disclosed are a method for preparing icariside II represented by Formula 1, which inhibits the glycosylation of glycoprotein enzyme tyrosinase by inhibiting the enzymatic activity of alpha-glucosidase, which is an enzyme in the glycosylation of tyrosinase, as well as a skin whitening composition. | 2010-03-11 |
20100062493 | METHOD FOR PRODUCING AN L-AMINO ACID OR A NUCLEIC ACID - A method is described for producing an L-amino acid or a nucleic acid by culturing a microorganism having an ability to produce the L-amino acid or nucleic acid in a liquid medium in a fermentation tank containing a stirring impeller, and optionally adding seed crystals to the medium as required to produce and accumulate crystals of the L-amino acid or nucleic acid in the medium, and collecting crystals of the L-amino acid or nucleic acid from the culture. The power density of the stirring impeller is controlled to be 2.4 kW/m | 2010-03-11 |
20100062494 | ENZYMATIC OLIGONUCLEOTIDE PRE-ADENYLATION - Methods and compositions for making and using pre-adenylated oligonucleotide sequences are provided. | 2010-03-11 |
20100062495 | Homologous recombination-based DNA cloning methods and compositions - Methods and compositions for cloning a donor DNA molecule into an acceptor vector at a predetermined location are described. The methods are based on homologous recombination mediated by in vitro treatment of the donor DNA and the acceptor vector with an enzyme cocktail containing an exonuclease and a single-stranded DNA binding protein. | 2010-03-11 |
20100062496 | L-AMINO ACID PRODUCING MICROORGANISM AND A METHOD FOR PRODUCING AN L-AMINO ACID - A microorganism belonging to the family | 2010-03-11 |
20100062497 | MICROORGANISM PRODUCING AN AMINO ACID OF THE L-GLUTAMIC ACID FAMILY AND A METHOD FOR PRODUCING THE AMINO ACID - A microorganism is cultured in a medium, and is able to produce one or two or more kinds of L-amino acids including L-glutamic acid, L-glutamine, L-proline, L-ornithine, L-citrulline and L-arginine, and is modified to increase α-ketoglutarate synthase activity. The L-amino acids are collected from the medium or the cells. | 2010-03-11 |
20100062498 | POLYPEPTIDE BEING CAPABLE OF INCREASING THE PRODUCTION OF L-METHIONINE, A MICROORGANISM THAT OVEREXPRESSES SAID POLYPEPTIDE AND A PROCESS OF PREPARING L-METHIONINE IN HIGH YIELD USING SAME - The present invention relates to a polypeptide capable of increasing the production of L-methionine in a microorganism. In particular, the present invention relates to an YgaZ and YgaH polypeptide or a complex thereof, referred to herein as YgaZH polypeptide, which are novel putative L-methionine exporters, polynucleotides encoding the same, a recombinant vector comprising the polynucleotide, a microorganism transformed with the recombinant vector, and a method for producing L-methionine and/or S-adenosyl-methionine, comprising the steps of culturing the transformed microorganism to produce L-methionine and/or S-adenosyl-methionine, and isolating L-methionine and/or S-adenosyl-methionine. The transformed microorganism of the present invention produces L-methionine in a high yield, thereby being used for medicinal and pharmaceutical industries and feed industry, in particular, animal feeds | 2010-03-11 |
20100062499 | KETOREDUCTASE POLYPEPTIDES FOR THE STEREOSELECTIVE PRODUCTION OF (4S)-3-[(5S)-5-(4-FLUOROPHENYL)-5-HYDROXYPENTANOYL]-4-PHENYL-1,3-OXAZOLID- IN-2-ONE - The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme including the capability of reducing 5-((4S)-2-oxo-4-phenyl(1,3-oxazolidin-3-yl))-1-(4-fluorophenyl)pentane-1,5-dione to (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize the intermediate (4S)-3-[(5S)-5-(4-fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one in a process for making Ezetimibe. | 2010-03-11 |
20100062500 | METHOD FOR THE REESTERIFICATION OR ESTERIFICATION OF SIDE CHAINS IN POLYMERS - The present invention relates to a process for esterifying or transesterifying side chains in polymers, comprising the following steps
| 2010-03-11 |
20100062501 | METHOD - The present application provides a method of reducing and/or removing diglyceride from an edible oil, comprising admixing an edible oil with an acyl acceptor substrate and a diglyceride:glycerol acyltransferase, wherein the diglyceride:glycerol acyltransferase is characterized as an enzyme which in an edible oil is capable of transferring an acyl group from a diglyceride to glycerol. The diglyceride:glycerol acyltransferase can comprise the amino acid sequence motif GDSX. The present invention also relates to the use of a diglyceride:glycerol acyltransferase in the manufacture of an edible oil, for reducing and/or removing diglyceride from said edible oil and to the use of said enzyme in the manufacture of a foodstuff comprising an edible oil for improving the crystallization properties of said foodstuff. | 2010-03-11 |
20100062502 | MANIPULATION OF SNF1 KINASE FOR ALTERED OIL CONTENT IN OLEAGINOUS ORGANISMS - Methods of increasing the total lipid content in a eukaryotic cell, the total content of polyunsaturated fatty acids [“PUFAs”], and/or the ratio of desaturated fatty acids to saturated fatty acids by reducing the activity of the heterotrimeric SNF1 protein kinase are disclosed. Preferably, the chromosomal genes encoding the Snf1 α-subunit, Gal83 β-subunit or Snf4 γ-subunit of the SNF1 protein kinase, the upstream regulatory genes encoding Sak1, Hxk2, Glk1 or Reg1, or the downstream genes encoding Rme1, Cbr1 or Snf3 are manipulated in a PUFA-producing strain of the oleaginous yeast | 2010-03-11 |
20100062503 | Lactic acid production from concentrated raw sugar beet juice - The present invention is in the field of the preparation of lactic acid by means of fermentation on industrial scale wherein a concentrated raw beet juice having a Brix of at least 60 is used as fermentation substrate. After dilution to the desired initial sugar concentration and addition of nutrients, the juice is fermented to lactic acid and/or lactate by means of a lactic acid-producing microorganism. Said concentrated raw beet juice is prepared by: washing and cutting sugar beet and extracting the cossettes in water, removing the beet pulp from the resulting raw beet juice, and heat treating the raw beet juice at a temperature between 50 and 90 degrees Celsius, and concentrating the raw beet juice to at least 60 Brix. | 2010-03-11 |
20100062504 | Nerolidol, Terpene, and Terpene Deriviative Synthesis - According to one embodiment, the description relates to a method of nerolidol production. The method includes culturing a yeast strain lacking functional squalene synthase and overproducing HMG CoA reductase in synthetic medium lacking uracil and producing nerolidol. The pH of the medium may be adjusted to an acidic level to further increase nerolidol production. Other chemicals may also be produced by this method. The nerolidol or other chemicals may be removed from the yeast or medium or both. The medium may additionally contain a polyaromatic resin, which may adsorb nerolidol or other chemicals. | 2010-03-11 |
20100062505 | BUTANOL PRODUCTION BY METABOLICALLY ENGINEERED YEAST - There are disclosed metabolically-engineered yeast and methods of producing n-butanol. In an embodiment, metabolically-engineered yeast is capable of metabolizing a carbon source to produce n-butanol, at least one pathway produces increased cytosolic acetyl-CoA relative to cytosolic acetyl-CoA produced by a wild-type yeast, and at least one heterologous gene encodes and expresses at least one enzyme for a metabolic pathway capable of utilizing NADH to convert acetyl-CoA to n-butanol. In another embodiment, a method of producing n-butanol includes (a) providing metabolically-engineered yeast capable of metabolizing a carbon source to produce n-butanol, at least one pathway produces increased cytosolic acetyl-CoA relative to cytosolic acetyl-CoA produced by a wild-type yeast, and at least one heterologous gene encodes and expresses at least one enzyme for a metabolic pathway utilizing NADH to convert acetyl-CoA to n-butanol; and (b) culturing the yeast to produce n-butanol. Other embodiments are also disclosed. | 2010-03-11 |
20100062506 | THERMOTOLERANT ETHANOL-PRODUCING YEAST AND ETHANOL PRODUCTION METHOD UTILIZING THE SAME - The present invention provides a novel yeast strain capable of producing ethanol through fermentation with a high degree of efficiency at a temperature of 37° C. or higher, preferably a temperature ranging from 40 to 49° C. or higher, and also a method for producing ethanol by utilizing the yeast strain, and further, ethanol produced by the method. Therefore, in the present invention, an yeast strain (Deposit No. NITE BP-283, etc) belonging to species | 2010-03-11 |
20100062507 | METHOD FOR PRODUCING FUEL USING STACKED PARTICLE BIOREACTOR - A bioreactor for producing synfuel from carbonaceous material includes a stacked particle heap comprising biodegradable carbonaceous material, an aerobic microbial consortium fermenting the biodegradable carbonaceous material into synfuel, and a gas impermeable barrier operatively covering the stacked particle heap. The covered particle heap is purged with at least one non-oxygenated gas. The bioreactor also includes a supply of anaerobic microorganisms which biodegrade the carbonaceous material within the stacked particle heap into synfuel. The synfuel is mixed with at least one reactor byproduct. The reactor byproducts are separated from the synfuel, which may include synthetic petroleum, alcohol, oil, and/or a gaseous fuel containing methane. | 2010-03-11 |
20100062508 | Droplet Actuator Loading and Target Concentration - A droplet actuator and method of providing a droplet comprising an target substance on the droplet actuator, and including discrete flow and continuous flow functionality. Discrete flow function is controlled by electrodes arranged for conducting droplet operations on a substrate surface. The continuous flow function includes a fluid path arranged for flowing a fluid therethrough. The discrete flow and continuous flow functions may be by a barrier, including a second fluid path through the barrier. The continuous flow function may include a capture surface comprising a component having an affinity for the target substance. Methods of the invention may include flowing a fluid comprising the target substance through the fluid path; capturing the target substance on the capture surface; and forming a droplet in the discrete flow region via the second fluid path and the electrodes comprising the captured target substance. | 2010-03-11 |
20100062509 | HIGHLY POROUS MAGNETIC TEMPORARY FIXED BED - The present invention relates to a fixed bed, for example for the isolation and/or purification of components originating from a biological system, which fixed bed comprises magnetic beads and a magnetizable fabric arranged at least in part in the fixed bed, a fluidized bed-fixed bed, which comprises the fixed bed of the invention after application of an alternating magnetic field, and also to a process for the isolation and/or purification of components originating from a biological system. | 2010-03-11 |
20100062510 | Protein exhibiting activity of pyrethrin biosynthetic enzyme, gene encoding the protein, and vector bearing the gene - The present invention relates to an enzyme determining amino acid sequences of an enzyme involved in pyrethrin biosynthesis and a base sequence of the gene thereof; constructing vectors bearing the gene and transformants; and extractable from plant bodies producing pyrethrin by applying such creative techniques to plant bodies with faster growth aiming to provide a method to efficiently produce pyrethrin; and the enzyme is a gene encoding a protein of the following (i) or (ii):
| 2010-03-11 |
20100062511 | MODIFIED ENZYMES, METHODS TO PRODUCE MODIFIED ENZYMES AND USES THEREOF - The invention is directed to modified xylanases having increased stability in harsh industrial environments, such as increased pH and/or temperature. | 2010-03-11 |