10th week of 2012 patent applcation highlights part 33 |
Patent application number | Title | Published |
20120058140 | TOPICAL COMPOSITIONS FOR INHIBITING MATRIX METALLOPROTEASES AND PROVIDING ANTIOXIDATIVE ACTIVITIES - A topical composition according to the present invention for use in a skin care regimen that provides matrix metalloprotease (MMP) inhibiting activity, tissue inhibitor of metalloprotease (TIMP) inducing activity, and immediate and delayed antioxidative activity. Preferably, the topical composition comprises at least one MMP inhibitor, a TIMP inducing agent, | 2012-03-08 |
20120058141 | CHIMERIC NEWCASTLE DISEASE VIRUSES AND USES THEREOF - Described herein are chimeric Newcastle disease viruses engineered to express a heterologous interferon antagonist and compositions comprising such viruses. The chimeric Newcastle disease viruses and compositions are useful in the treatment of cancer. | 2012-03-08 |
20120058142 | VACCINE FOR PROTECTION AGAINST SHIGELLA SONNEI DISEASE - Compositions and methods for protecting a susceptable host against an infection of | 2012-03-08 |
20120058143 | STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS - The invention provides proteins from | 2012-03-08 |
20120058144 | LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS - The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structures XIV or XVII. | 2012-03-08 |
20120058145 | METHOD FOR PRODUCING VIRUS FROM CELL CULTURE INVOLVING HOMOGENIZATION - A method of purifying a virus, or a viral antigen thereof, from a culture of infected cells comprising at least the steps of: (a) collecting the virus-containing cell culture medium, and (b) purifying the virus, wherein at least one homogenization step is implemented during the purification to obtain a virus homogenate. | 2012-03-08 |
20120058146 | IMMUNOGENS FROM UROPATHOGENIC ESCHERICHIA COLI - Disclosed herein are various genes that can be included in immunogenic compositions specific for pathogenic | 2012-03-08 |
20120058147 | Geographically Region Specific Allergy Immunotherapy for Companion Animals - Implementations and techniques for providing geographically region specific allergy immunotherapy for companion animals are generally disclosed. | 2012-03-08 |
20120058148 | CERTAIN AMINOALKYL GLUCOSAMINIDE PHOSPHATE COMPOUNDS AND THEIR USE - Compounds that are adjuvants and immunoeffectors are described and claimed. The compounds augment antibody production in immunized animals as well as stimulate cytokine production and activate macrophages. Compositions and methods for using the compounds as adjuvants and immunoeffectors are also disclosed. | 2012-03-08 |
20120058149 | TREATMENT OF INFECTION - The invention relates to compositions including a substance useful as an adjuvant for potentiating an immune response, and methods of using the composition in individuals with infections of tissue within or adjacent to a transformation zone, such as the transformation zone of the cervix or anal canal. | 2012-03-08 |
20120058150 | Methods for Delivering Compositions by Electrospraying a Medical Device - Methods are provided for administering a phospholipid composition to a subject, comprising coating a medical device with at least one layer of a phospholipid composition, wherein the coating is achieved by electrospraying the device with the composition, and wherein the composition is carrying or can carry at least one therapeutic agent. | 2012-03-08 |
20120058151 | NANOPARTICULATE COMPOSITIONS OF POORLY SOLUBLE COMPOUNDS - The present invention relates to a method for the production of a nanoparticulate pharmaceutical composition. The method comprises the steps of a) suspending in water a poorly soluble active ingredient without the presence of a detergent, b) mechanically treating said suspension to obtain particles comprising the active ingredient with an effective average size of less than about 5000 nm, c) contacting said active ingredient or suspension with a first polyelectrolyte during and/or before mechanically treating, d) optionally contacting said suspension with a one or more second or further polyelectrolytes during, before and/or after mechanically treating, e) optionally drying said suspension. The invention also pertains to the pharmaceutical compositions obtained by the method of the invention. | 2012-03-08 |
20120058152 | BONE REGENERATION MATERIALS BASED ON COMBINATIONS OF MONETITE AND OTHER BIOACTIVE CALCIUM AND SILICON COMPOUNDS - The present invention incorporates new materials for bone regeneration, methods for their manufacture, and application in traumatology surgery, maxillo facial surgery, dental surgery, orthognatic surgery, endodontics, ophthalmology, neurosurgery and/or osteoporotic processes, and other indications where bone regeneration is required. In particular, the present invention incorporates synthetic materials with a 20% to a 95%, preferably between 40% and 90% in mass of monetite [Ca | 2012-03-08 |
20120058153 | SYNTHETIC NANOCARRIER VACCINES COMPRISING PROTEINS OBTAINED OR DERIVED FROM HUMAN INFLUENZA A VIRUS HEMAGGLUTININ - This invention relates to compositions and methods that can be used immunize a subject against influenza. Generally, the compositions and methods include polypeptides obtained or derived from human influenza A virus hemagglutinin. | 2012-03-08 |
20120058154 | SYNTHETIC NANOCARRIER VACCINES COMPRISING PEPTIDES OBTAINED OR DERIVED FROM HUMAN INFLUENZA A VIRUS M2E - This invention relates to compositions and methods that can be used immunize a subject against influenza. Generally, the compositions and methods include peptides obtained or derived from human influenza A virus M2 protein. | 2012-03-08 |
20120058155 | SLOW-DEGRADING POLYMERS FOR UNDELAYED AND SUSTAINED DRUG DELIVERY - The invention provides polymers and methods for their use. Certain embodiments of the invention provide slow degrading microspheres for undelayed and sustained drug delivery. | 2012-03-08 |
20120058156 | ACTIVATED LEUKOCYTE COMPOSITION AND USES FOR WOUND HEALING - Disclosed are therapeutic, blood-derived activated leukocyte compositions, methods of making them, and methods of using the compositions to repair or promote the prevention and healing of wounds. | 2012-03-08 |
20120058157 | Methods of Treating Cardiovascular Disorders Associated with Atherosclerosis - Layered phyllosilicates are useful for adsorbing and/or binding to cholesterol in the gastrointestinal (GI) tract and, thereby, reducing blood cholesterol in a patient. Accordingly, provided herein is a method of reducing hypercholesteremia in a mammal comprising administering to said mammal a protonated and at least partially exfoliated layered phyllosilicate material alone and in combination with other cholesterol-reducing agents in an amount effective to reduce hypercholesteremia in said mammal. Also provided are methods of treating a cardiovascular disorder associated with atherosclerosis in a mammalian subject comprising administering to the subject a layered phyllosilicate material in an amount effective to reduce atherosclerotic lesion formation in the subject. | 2012-03-08 |
20120058158 | Sublingual Pharmaceutical Composition Comprising a Neutral Oil - The invention provides pharmaceutical compositions for the sublingual delivery of medicaments comprising a neutral oil and a medicament soluble in said oil, providing that said medicament is not nitroglycerine. The invention also provides delivery devices adapted for sublingual delivery of such compositions. | 2012-03-08 |
20120058159 | Treatment of Animal Litter With Ferric Sulfate Granules - Methods of treating animal litter and/or bedding material for control of volatile ammonia and soluble phosphorous include applying granular partially hydrated ferric sulfate to the litter. The partially hydrated ferric sulfate ranges from gray to tan in color and is spread onto the litter at a rate effective to reduce ammonia volatilization and reduce soluble phosphorous. Relative to reagent grade ferric sulfate, the partially hydrated ferric sulfate exhibits lower hygroscopicity and higher deliquescence. The ferric sulfate is prepared by a process comprising oxidizing ferrous sulfate with sulfuric acid using a molecular oxygen oxidizing agent at an elevated pressure relative to atmospheric and at a temperature of 60° C. to 140° C. to produce a gray to tan colored granular product. | 2012-03-08 |
20120058160 | PARTICULATE MATERIALS - Embodiments of the invention relate to particles of active substances, methods for preparing the particles, formulations containing the particles, and metered dose inhalers containing such particles or formulations. In one embodiment, a composition of an aerosol formulation is provided and contains a particulate active substance of non-micronized, solid particles having a mass median aerodynamic diameter of less than 10 μm suspended in a hydrofluorocarbon fluid vehicle at a concentration within a range from about 0.2% w/v to about 5% w/v. The aerosol formulation exhibits a flocculation volume of about 85% or greater about 1 minute after mixing the particulate active substance and the hydrofluorocarbon fluid vehicle. The particulate active substance contains an alkaloid ergotamine, pharmaceutically acceptable salts thereof, analogues thereof, or derivatives thereof. In some examples, the alkaloid ergotamine contains dihydroergotamine, such as dihydroergotamine mesylate and the hydrofluorocarbon fluid vehicle contains HFA 134a, HFA 227ea, or mixtures thereof. | 2012-03-08 |
20120058161 | ALKYLATED SEMI SYNTHETIC GLYCOSAMINOGLYCOSAN ETHERS, AND METHODS FOR MAKING AND USING THEREOF - Described herein are alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated and alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including use for ocular or ophthalmic treatment. | 2012-03-08 |
20120058162 | STABLE, SPRAY DRYED, IMMUNOGENIC, VIRAL COMPOSITIONS - Viruses, and particularly genetically engineered, replication deficient viruses such as adenoviruses, poxviruses, MVA viruses, and baculoviruses which encode one or more antigens of interest, such as TB, malarial, and HIV antigens, are spray dried with a mannitol-cyclodextrin-trehalose-dextran (MCTD) to form a powder where the viability of the viruses are maintained at a suitable level for mass vaccinations after spray drying, and where the viability of the viruses are maintained at suitable level over a period of storage time, even in the presence of humidity. | 2012-03-08 |
20120058163 | WATER-DISPERSIBLE AND MULTICOMPONENT FIBERS FROM SULFOPOLYESTERS - Disclosed are water-dispersible fibers derived from sulfopolyesters having a Tg of at least 25° C. The fibers may contain a single sulfopolyester or a blend of a sulfopolyester with a water-dispersible or water-nondispersible polymer. Also disclosed are multicomponent fibers comprising a water dispersible sulfopolyester having a Tg of at least 57° C. and a water non-dispersible polymer. The multicomponent fibers may be used to produce microdenier fibers. Fibrous articles may be produced from the water-dispersible fibers, multicomponent fibers, and microdenier fibers. The fibrous articles include water-dispersible and microdenier nonwoven webs, fabrics, and multilayered articles such as wipes, gauze, tissue, diapers, panty liners, sanitary napkins, bandages, and surgical dressings. Also disclosed is a process for water-dispersible fibers, nonwoven fabrics, and microdenier webs. The fibers and fibrous articles have further applications in flushable personal care and cleaning products, disposable protective outerwear, and laminating binders. | 2012-03-08 |
20120058164 | CLEANING OR COSMETIC COMPOSITIONS COMPRISING NATURAL ZEOLITES - The invention describes compositions which are useful as cleansers of the skin. The compositions described comprise zeolitic ingredients which are in general softer than known products. The natural zeolitic ingredients are inherently soft. The softness is due to a number of factors including but not limited to younger zeolitic rock types, softer constituent elements, more porous rock types and less dense rock types. The overall softness provided by the compositions according to the invention provides a cleaning product that is softer to the skin, especially the human skin. | 2012-03-08 |
20120058165 | Opacifying Lotion - A lotion for opacifying a wet wipe. A wet wipe may comprise a lotion, the lotion comprising an opacifying agent. The lotion or the substrate may further comprise a retention aid. The substrate may comprise an opacifying agent the same as or different than the opacifying agent of the lotion. A method for opacifying a wet wipe by loading onto a wipe substrate a lotion comprising an opacifying agent. A method for aesthetically modifying a wet wipe by selectively loading onto a wipe substrate a lotion comprising an opacifying agent. | 2012-03-08 |
20120058166 | FILAMENTS COMPRISING A NON-PERFUME ACTIVE AGENT NONWOVEN WEBS AND METHODS FOR MAKING SAME - Filaments that contain a filament-forming material and an additive, nonwoven webs, and methods for making such filaments are provided. | 2012-03-08 |
20120058167 | METHODS FOR TREATING SCARS AND AGING SKIN - Beneficial topical compositions for treating scar or aging skin are provided. In one embodiment, the compositions include | 2012-03-08 |
20120058168 | Animal Attractant - Disclosed herein are compositions and methods useful for attracting animals to a site determined by the user of the compositions and method disclosed herein. Disclosed are compositions that contain an absorbent material and an animal attractant. The animal attractant may be in the form of a liquid and may have a urine scent, a food scent, or a combination thereof. | 2012-03-08 |
20120058169 | Silver Iodate Compounds Having Antimicrobial Properties - The present invention is compositions, methods of use, methods of treating, and articles of manufacture that include at least one silver iodate for imparting antimicrobial properties, particularly as it relates to the manufacture, use, and properties of medical devices. The invention also includes obtaining and using one or more silver iodate reaction products from a diperiodatoargentate, wherein the reaction products are obtained using a hydrothermal reaction. | 2012-03-08 |
20120058170 | DRUG DELIVERY BY CARBON NANOTUBE ARRAYS - The invention generally relates to carbon nanotube based drug delivery methods, devices, and compositions. More particularly, the invention relates to controlled drug delivery using anchored carbon nanotube arrays. | 2012-03-08 |
20120058171 | ZOO-TECHNICAL DRUG DELIVERY DEVICE - The present invention relates to a veterinary zoo-technical drug delivery system (device) for the simultaneous release of two or more active substances, which system releases the active substances in a substantially constant ratio over a prolonged period of time. The drug delivery system can be in different forms, such as e.g. an implant, or a intravaginal device such as a helical coil, a spring or a ring. | 2012-03-08 |
20120058172 | PLANT EXTRACTS FOR USE IN BRAIN MODULATION - Compounds obtainable from plants, e.g. of the genus | 2012-03-08 |
20120058173 | SELECTIVE STARCH FEEDING PROTOCOL - The present invention includes a method for improving milk production in a ruminant. An amount of ruminally digestible starch in relation to the dry matter of a feed is manipulated to include a first selected ratio of ruminally digestible starch in relation to the dry matter of the feed which is fed to the ruminant during a first time interval after parturition. After the first time interval, the amount of ruminally digestible starch component in the dry matter of the feed is adjusted to a second ratio, lower than the first ratio, and fed to the ruminant. | 2012-03-08 |
20120058174 | FABRICATION OF INTERCONNECTED MODEL VASCULATURE - Methods of fabricating a substantially interconnected model vasculature, as well as compositions formed from such methods are provided. In some embodiments, the methods may comprise forming a non-woven fiber network comprising a plurality of fibers and a void space; backfilling the void space of the fiber network; and removing the fibers to form a substantially interconnected vascular network. | 2012-03-08 |
20120058175 | Transdermal Preparation - Provided is a transdermal preparation, which is capable of long-term (1-day to 7-day) release of a basic drug from a preparation, continuously and at a consistent concentration; shows little reduction over time in the drug content, even if multiple drugs are contained in the preparation; and is produced by a simple process. The transdermal preparation comprises a substrate, and an adhesive layer containing a basic drug and a water-soluble polymer. | 2012-03-08 |
20120058176 | CONTROLLED RELEASE DELIVERY SYSTEM FOR NASAL APPLICATIONS AND METHOD OF TREATMENT - This invention relates to a gel formulation for nasal administration of a controlled release formulation of hormones to the systemic circulation and/or to the brain. The special lipophilic or partly lipophilic system of the invention leads to higher bioavailability of the active ingredient caused by sustained serum levels in plasma but also leads to a more favorable serum level profile. The special lipophilic or partly lipophilic system also allows for the modulation of brain functioning. The invention also relates to the nasal administration of steroid hormones for treatment of female sexual dysfunction (FSD) or female arousal disorder. | 2012-03-08 |
20120058177 | NANOPARTICLE-BASED TUMOR-TARGETED DRUG DELIVERY - The present invention provides an aqueous tumor-targeting liposome nanoparticle composition comprising an aqueous dispersion of liposome nanoparticles. The nanoparticles preferably encapsulate an anti-cancer chemotherapeutic agent, which can be added to a pre-formed liposome composition or can be incorporated in the liposomes during the formation of the liposomes. The liposome nanoparticles comprise a legumain-targeting lipid admixed with one or more other micelle or vesicle-forming lipid materials in the form of nanoparticulate liposomes dispersed in an aqueous carrier. A preferred tumor-targeting liposome nanoparticle composition comprises (a) a legumain-targeting lipid component, (b) a zwitterionic lipid component; (c) an amino-substituted lipid component; (d) a neutral lipid component; and (e) polyethylene glycol-conjugated lipid component. The legumain-targeting lipid component comprising a hydrophobic lipid portion covalenetly attached to a legumain-binding moiety. | 2012-03-08 |
20120058178 | Liposome Composition - The present invention provides a novel liposome composition containing eribulin or its pharmacologically permissible salt, and its method of manufacture. | 2012-03-08 |
20120058179 | Apparatus and process for encapsulating microparticles with liquid in soft gel capsules - The invention provides an apparatus for producing soft gel capsules having encapsulated therein microparticles, nanoparticles and fluids, said apparatus comprising: (a) two spreader boxes; (b) two casting drums; (c) a pair of rotary dies; (d) a liquid fill system (medicine pump system); (e) a wedge for heating gelatine ribbons and feeding said fill; and (f) one or more microgranule or nanogranule feeders located on each side of the rotary dies, said feeders being synchronized to rotate at the same tangential speed as the rotary dies. | 2012-03-08 |
20120058180 | Liver-specific Nanocapsules and Methods of Using - This disclosure describes liver-specific nanocapsules for specifically targeting liver cells. This disclosure also provides methods of using such liver-specific nanocapsules to deliver one or more cargo moieties to the liver cells. | 2012-03-08 |
20120058181 | Prebiotic Suppositories - A composition for vaginal insertion is in the form of a softgel, a two-part gelatin capsule, a tablet, or a suppository. The composition is designed to promote the growth of native vaginal flora, but does not promote the growth of | 2012-03-08 |
20120058182 | METHOD AND COMPOSITION FOR ADMINISTERING AN NMDA RECEPTOR ANTAGONIST TO A SUBJECT - The invention provides methods and compositions for administering an NMDA receptor antagonist (e.g., memantine) to a subject. | 2012-03-08 |
20120058183 | RETIGABINE TABLETS, PREFERABLY HAVING MODIFIED RELEASE - The invention relates to tablets, especially tablets with modified release, containing (a) retigabine and a combination of (b) water-soluble excipient and (c) non-water-soluble excipient; and a process for producing them. | 2012-03-08 |
20120058184 | FORMULATIONS AND USES OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES FOR THE TREATMENT OF MALES - The instant application provides methods and compositions for the treatment of male subjects having ulcerative colitis. | 2012-03-08 |
20120058185 | STABLE PHARMACEUTICAL COMPOSITIONS OF OLANZAPINE AND PROCESS FOR THEIR PREPARATION - The present invention provides a stable pharmaceutical composition of Olanzapine or its pharmaceutically acceptable salt comprising coated tablet formulations of Olanzapine or its pharmaceutically acceptable salt, wherein the coating consists essentially of pectin or copovidone, and a process of making the same. | 2012-03-08 |
20120058186 | THERAPEUTIC OR PROPHYLACTIC AGENT FOR DYSKINESIA - The present invention relates to a stable orally disintegrating coated tablet containing a drug, wherein the tablet is coated with a coating layer containing a water-soluble substance and a polyvinyl alcohol resin of not less than 5% by weight based on the weight of the coating layer, the water-soluble substance dissolving in an amount of 1 g or more in less than 10 mL of water at 20° C., having a hydroxyl group(s) in its molecule, and having a molecular weight of not more than 200 per a unit hydroxyl group. There is provided a stable orally disintegrating coated tablet which does not cause a crack in the coating layer even when the orally disintegrating tablet has been swollen by moisture absorption under high humidity, while ensuring rapid disintegration properties in an oral cavity. In the case of an orally disintegrating tablet containing a light-unstable drug, degradation of the drug can be suppressed by blending a light shading agent in the coating layer. | 2012-03-08 |
20120058187 | WATER-IN-OIL TYPE EMULSION FOR TREATING A DISEASE OF THE EYE - A composition is described herein for administering with a sustained release kinetic a therapeutically effective amount of a therapeutic agent to a subject in need thereof for treating diseases or conditions of the eye, wherein the composition is an water-in-oil type emulsion comprising an oil phase, a lipophilic surfactant dissolved in the oil phase, an aqueous phase dispersed in the oil phase, a hydrophilic therapeutic agent dissolved in the aqueous dispersed phase, and wherein the composition is intraocularly injectable, wherein the composition has a density lower than 1. Some embodiments also relate to a pharmaceutical composition or to a medicament comprising a composition described herein, and to a method for treating a condition or disease of the eye comprising administering a therapeutic amount of a composition described herein. | 2012-03-08 |
20120058188 | LIPID ENCAPSULATED INTERFERING RNA - The present invention provides compositions and methods for silencing gene expression by delivering nucleic acid-lipid particles comprising a siRNA molecule to a cell. | 2012-03-08 |
20120058189 | PROCESS FOR MAKING A CRYSTALLINE ZILPATEROL SALT - This invention generally relates to processes for making a crystalline zilpaterol salt, particularly zilpaterol hydrochloride. This invention also relates to methods of treatment using a crystalline zilpaterol salt prepared in accordance with this invention to increase the rate of weight gain, improve feed efficiency, and/or increase carcass leanness in livestock, poultry, and fish. | 2012-03-08 |
20120058190 | FOOD CONTAINING PROLACTIN - A nutritional Composition for a subject, comprising prolactin identical or similar or analogous to prolactin found in a natural food source, and at least one protective layer, wherein release of said prolactin from the composition in said subject is the result of an environmental event. | 2012-03-08 |
20120058191 | CARBON-BEARING NSP3 NANOPARTICLE AND ITS SYNTHESIS ROUTE - The invention relates to nanotechnology. The carbon-bearing nanoparticle consists of a cubical carbon monocrystal nucleus, the size of which is equal to or less than 4 nm, and a monocrystalline carbon shell having an SP | 2012-03-08 |
20120058192 | SUNSCREEN COMPOSITIONS - Sunscreen compositions containing a discontinuous oil phase dispersed in a continuous water phase, at least 10% by weight of an organic UV-filter, a water-insoluble, C | 2012-03-08 |
20120058193 | INJECTABLE SMART GEL AND METHOD FOR FABRICATING THE SAME - An injectable smart gel and a method for fabricating the same are disclosed. A basic structural stabilizer/polymeric electrolyte and a diluting solution are added to a modified chitosan to regulate the chitosan solution to have a pH value closing to that of the human body and form a flowable chitosan sol. The flowable chitosan sols formed thereby are respectively converted into inflowable chitosan gels via increasing the temperature thereof to the human body temperature, and via adding calcium ion or regulating the chitosan sol into an acidic solution. The injectable smart gel fabricated thereby is injectable and able to function as a carrier of magnetism-sensitive medicine-containing nanocapsules. The medicine can be released to the injectable smart gel with an external non-contact force, such as a magnetic field, an electric field or an ultrasonic wave, for long-acting and multi-stage medicine delivery. The present invention is very useful in biomedical engineering. | 2012-03-08 |
20120058194 | PHARMACEUTICAL FORMULATIONS COMPRISING SUBSTITUTED BENZIMIDAZOLE DERIVATIVES - Stabilized substituted benzimidazole modified release pharmaceutical formulations with at least two drug-containing fractions, wherein the release from a first fraction precedes the release from a second fraction, pharmaceutical excipients, processes for preparing the stable formulations, packaging therefor, and their use in treatment of erosive esophagitis and heartburn associated with non-erosive gastroesophageal reflux disease. | 2012-03-08 |
20120058195 | MICROENCAPSULATION OF BIOACTIVE SUBSTANCES AND METHODS OF MAKING THE SAME - The present invention relates to microparticles and methods of making such microparticles that protect a bioactive substance from heat, humidity and oxidation. A microparticle comprising a bioactive substance, an agglomerating agent, an emulsifier and solid fats is disclosed. A method to produce a microparticle comprising an agglomerated bioactive substance enrobed in a double layer of solid fats and emulsifier is also disclosed. | 2012-03-08 |
20120058196 | PHARMACEUTICAL COMPOSITIONS OF DEXTRAN POLYMER DERIVATIVES AND A CARRIER MATERIAL - Pharmaceutical compositions are provided comprising (a) nanoparticles of an active agent and a dextran polymer derivative, and (b) a carrier material. | 2012-03-08 |
20120058197 | COMPOSITIONS COMPRISING WATER WITH DEUTERIUM FOR THE PREVENTION OR TREATMENT OF ALLERGIC DISEASES AND A PROCESS FOR THE PREPARATION THEREOF - The invention relates to pharmaceutical and food compositions for the prevention or treatment of allergic diseases and a process for the preparation thereof. The process of the invention comprises mixing water having 0.01-135 ppm deuterium content (preferably prepared by known electrolysis or distillation) with usual additives, and formulating this mixture by usual pharmaceutical or food industrial methods to pharmaceutical or food products, preferably by applying standard flavors, aromas and other additives used in the manufacturing of medicines, non-alcoholic drinks or beer. | 2012-03-08 |
20120058198 | METHODS FOR TREATING AND PREVENTING PNEUMONIA AND VENTILATOR-ASSOCIATED TRACHEOBRONCHITIS - The invention relates to methods for treating bacterial infection of the respiratory tract, including pneumonias, such as ventilator-associated pneumonia, and to methods for treating ventilator-associated tracheobronchitis, comprising administering an effective amount of a salt formulation as an aerosol to the respiratory tract of an individual in need thereof. The formulations can also be used to reduce transmission of pathogen which can infect the respiratory tract, cause pneumonia or cause ventilator-associated tracheobronchitis. | 2012-03-08 |
20120058199 | COMPOSITIONS, USE AND METHOD FOR THE USE OF SURFACE ACTIVE PROTEINS IN TOPICAL DRUG DELIVERY ACROSS KERATIN - The present invention provides the use of surface active proteins, especially class I and class II hydrophobins, in topically applied pharmaceutical formulations. The invention is particularly directed to topically applied pharmaceutical products for enhancing the penetration to achieve a transungual delivery of a prophylactically and/or therapeutically effective amount of an active ingredient (drug) to a patient (including animals and humans) into and/or through a nail, of the animal or human body, in order to treat one or more of a variety of diseases or disorders. Related embodiments of the invention are also disclosed. | 2012-03-08 |
20120058200 | PROCESS FOR THE PREPARATION OF LANTHANUM CARBONATE DIHYDRATE - Present invention relates to a process for the preparation and pharmaceutical usage of dihydrate form of lanthanum carbonate. Present process produces lanthanum carbonate dihydrate (La2(CO3)3.2H2O) free of lanthanum hydroxycarbonate and is stable at ambient condition. Lanthanum carbonate dihydrate exhibit improved performance over standard lanthanum carbonate tetrahydrate in phosphate binding studies. Lanthanum carbonate dihydrate is useful for the treatment of hyperphosphataemia in patients with renal failure. | 2012-03-08 |
20120058201 | METHOD OF PREDICTING A PREDISPOSITION TO QT PROLONGATION - The present invention describes an association between genetic polymorphisms in the FAM13A1 (family with sequence similarity 13, member A1) gene and a predisposition to prolongation of the QT interval, and provides related methods for the prediction of such a predisposition, the administration of QT interval- prolonging compounds to individuals having such a predisposition, and determining whether a compound is capable of inducing QT prolongation. | 2012-03-08 |
20120058202 | Means and Method for Ovarian Cancer Prognosis - There is provided a method for determining whether a mammalian subject having an ovarian cancer belongs to a first or a second group, wherein the prognosis of subjects of the first group is better than the prognosis of subjects of the second group, comprising the steps of: a) evaluating an amount of RBM3 protein in at least part of a sample earlier obtained from the subject and determining a sample value corresponding to the evaluated amount; b) comparing said sample value with a predetermined refer-ence value; and if said sample value is higher than said ref-erence value, c1) concluding that the subject belongs to the first group; and if said sample value is lower than or equal to said reference value, c2) concluding that the sub-ject belongs to the second group. Related peptides, affinity ligands, uses and further methods are also provided. | 2012-03-08 |
20120058203 | METHODS FOR TREATING CANCER AND OTHER PATHOLOGICAL PROLIFERATING DISORDERS BY INHIBITING MITOSIS USING PYRROLO[2,3-D]PYRIMIDINES - The present invention provides methods for treating cancer and other pathological proliferating conditions by inhibiting mitosis using at least one pyrrolo[2,3- | 2012-03-08 |
20120058204 | USE OF OVER EXPRESSION OF CYSTATHIONINE GAMMA LYASE AS A PROGNOSTIC, DIAGNOSTIC AND THERAPEUTIC TARGET FOR CANCER - The present invention relates to a method of identifying an expression level of cystathionine gamma lyase (CTH) in a sample from a subject. The present invention further discloses a method of diagnosing a subject with cancer having risk of resistance to a platinum-based drug. The present invention also discloses a method for improving efficacy of a platinum-based drug in a subject suffering a cancer. | 2012-03-08 |
20120058205 | COMPOSITIONS AND TREATMENT REGIMES FOR REDUCING INFLAMMATION, END-ORGAN INJURY, AND/OR SYSTEMIC ENDOTOXEMIA - The invention relates to pharmaceutical compositions and treatment regimes useful in treating one or more of the following conditions: inflammation, kidney disease, eye disease, end-organ injury, systemic endotoxemia, and/or vitamin D resistance. The compositions and treatment regimes are also useful in reducing elevated CRP levels and/or elevated pro-inflammatory cytokines. | 2012-03-08 |
20120058206 | ANTIALLERGIC MARINE BIOPOLYMERS - The present invention relates to pharmaceutical compositions for administration to the respiratory tract, the gastrointestinal tract or the eyes. In particular, the invention relates to liquid formulations and dry powder compositions comprising carrageenan, and in particular iota and kappa carrageenan, and one or more therapeutic agents. These sprays, powders, and the gel that forms when they are administered to the respiratory tract, the gastrointestinal tract or the eyes, have now surprisingly been found to be a very effective way of prevention and treatment of type I allergies and intranasal administration of therapeutic agents. | 2012-03-08 |
20120058207 | ANTI-DIABETIC NUTRACEUTICAL COMPOSITION FROM PALM LEAF EXTRACT - A comestible composition with anti-diabetic property which is effective in lowering the blood glucose and help reduce oxidative stress in diabetics and have anti-diabetic properties that protect against diabetic complications, retarding diabetes related organ degeneration and effective to hinder or prevent ailments or conditions resulting from, or exacerbated by, a chronic increase in blood sugar including: tissue degeneration, cardiovascular disease, kidney degeneration, loss of cognitive function, weight loss, visual impairment, and vasomotor symptoms which contains extract from palm leaf. | 2012-03-08 |
20120058208 | Synergistic Composition for Enhancing Bioavailability of Curcumin - The present disclosure relates to a composition to enhance the bioavailability of curcumin. In one embodiment, a composition comprising plant extracts of curcumin, vanilla and ginger, wherein the extracts of ginger and vanilla are rich in gingerol and vanillin respectively, is provided. In other embodiments, curcumin, and one or more items selected from the group of vanilla, ginger and capsaicin is provided. | 2012-03-08 |
20120058209 | Magnolia Extract Containing Compositions - Disclosed is a composition and method for its use that includes | 2012-03-08 |
20120058210 | EXTRACT OF FRAXINUS EXCELSIOR SEEDS AND THERAPEUTIC APPLICATIONS THEREFOR | 2012-03-08 |
20120058211 | DEFINED DOSE THERAPEUTIC PHAGE - The invention provides therapeutic, defined-dose anti-bacterial phage preparations, methods to make such preparations, methods to treat bacterial infections using such preparations and methods to diagnose bacterial infections using such preparations. | 2012-03-08 |
20120058212 | MOLD HAVING MOVABLE PLATE-SHAPED CORES - A mold for fabricating an optical fiber connector is disclosed. The optical fiber connector includes a blind hole for accommodating an optical fiber and an aspherical lens portion for optically coaxial with the optical fiber. The mold includes a rod-shaped core for forming the blind hole and a plate-shaped core. The plate-shaped core includes an aspherical recess for forming the lens portion. The aspherical recess faces the rod-shaped core, and is adjustably movable relative to the first core so as to achieve alignment between the aspherical recess and the rod-shaped core. | 2012-03-08 |
20120058213 | METHOD AND APPARATUS FOR ROTARY MOLDING - A rotary molding system for molding food products, mold cavities formed when a mold shell rotates mold shapes disposed along the mold shell into a fill position between a fill plate and a wear plate. Molded food products are removed from mold cavities using knock-out cups, the use of air pressure, or the use of a vacuum source disposed below the mold cavity, without the need to slow the rotation of the mold shell. Knock-out cups may be used with a heating system to reduce accumulation of unwanted materials on the knock-out cups. The rotary molding system can also be used to form products with contoured surfaces. A smart tagging system can be used to ensure that compatible sets of mold shells and knock out cups are being used. A vacuum region may be disposed upstream of the fill position to remove air within the mold cavity prior to filling. | 2012-03-08 |
20120058214 | MULTIPLE PRESS MOLDING MACHINE - A multiple press molding machine may include a plurality of guide shafts and a plurality of die units. Each of the die units includes a pair of dies, a plurality of guide holes and a plurality of bushes each having a through bore. Each of the bushes is positioned so as to surround at least one open peripheries of each of the guide holes. The guide shafts are respectively inserted into the guide holes of the die units and the through bores of the bushes, so that die closing and opening motion can be guided. The through bore of each of the bushes has an inner diameter smaller than a diameter of each of the guide holes. | 2012-03-08 |
20120058215 | Rotary press, particularly for the manufacture of tablets - A rotary press, particularly for manufacturing tablets, has a rotarily driven rotor and at least one pressure roller unit which is detachably secured to a bearing device, particularly at least one bearing plate, by means of a retaining device. Provision is made here for a plurality of similar retaining devices to be arranged on the bearing device, wherein the pressure roller unit can optionally be secured to one of the retaining devices and/or transferred between them. | 2012-03-08 |
20120058216 | Method For Forming An Anodized Layer, Method For Manufacturing A Mold, and Mold - An anodized layer formation method of at least one example embodiment of the present invention includes the steps of: (a) providing an aluminum base which has a machined surface; (b) forming, in the surface of the aluminum base, a minute uneven structure which has a smaller average neighboring distance than an average neighboring distance of a plurality of minute recessed portions that an intended porous alumina layer has; and (c) after step (b), anodizing the surface of the aluminum base, thereby forming a porous alumina layer which has the plurality of minute recessed portions. According to at least one embodiment the present invention, a porous alumina layer which has uniformly-distributed minute recessed portions can be formed over a machined surface of an aluminum base. | 2012-03-08 |
20120058217 | TASTE DETERRENT AND DIET METHOD - A diet spray or powder that may be used by a dieter to render a portion of a meal unappetizing. After eating an initial portion of a meal, a dieter may apply a spray or powder to remaining food portions so as to inhibit further eating, and thus reduce total caloric intake and/or inhibit ingestion of additional portions. The use of the product can promote or strengthen a dieter's will-power in the face of surplus, but tempting, food by direct and/or psychological support. A method includes application of the spray or powder to the tempting foodstuff | 2012-03-08 |
20120058218 | FROZEN CONFECTIONERY HOLDER - A holder for confectioneries and particularly frozen confectioneries. The holder includes a receptacle having a shape that is complementary to the shape of the confectionery and being configured to allow a major portion of the confectionery to be exposed when the confectionery is received in and supported by the receptacle, and a handle coupled to a bottom portion of the receptacle to allow the holder to be hand held. The holder is particularly useful for holding frozen confectioneries such as ice cream bars, ice cream sandwiches, etc. that are not provided with handles. | 2012-03-08 |
20120058219 | BREWING METHOD - A method of brewing a beer comprising contacting a mash during lautering, and/or a wort after lautering but before wort boiling, with a thermostable protease. | 2012-03-08 |
20120058220 | SPARKLING ALCOHOLIC DRINK AND METHOD FOR PRODUCING THE SAME - Provided are a sparkling alcoholic beverage having improved drinkability and a method for producing the same. The method for producing a sparkling alcoholic beverage according to the present invention is a method for producing a sparkling alcoholic beverage, including: a pre-fermentation step ( | 2012-03-08 |
20120058221 | MASHING METHOD FOR THE PRODUCTION OF KVASS WORT - A mashing method for producing kvass wort and a method for producing kvass wort concentrate and kvass, where a first portion of mash, in particular a portion of rye mash, is mashed and is heated to a temperature lying below the boiling point (≦90°), a second portion of mash is mashed, and the mixed first and second portions of mash are heated in stages. | 2012-03-08 |
20120058222 | Use - The present invention relates to the use of an amylase and a lipolytic enzyme in combination to improve the stackability of bread, methods of preparing dough and baked products having a combination of such enzymes, as well as bread having particular bread stackability profiles. | 2012-03-08 |
20120058223 | COLD-ACTIVE BETA-GALACTOSIDASE, A METHOD OF PRODUCING SAME AND USE OF SUCH ENZYME - A novel cold-active beta-galactosidase is enzyme specific for lactose. The enzyme is thus useful in e.g. the food industry for catalyzing at low temperatures the hydrolysis of lactose disaccharide into its constituent monosaccharides, glucose and galactose. A method produces the cold-active beta-galactosidase by recombinant DNA technology. | 2012-03-08 |
20120058224 | PRODUCT AND PROCESS FOR ITS PREPARATION - The invention relates to a low-energy, low-fat or fat-free, high-protein soured or unsoured product prepared by means of a crosslinking enzyme, and to a process for the preparation thereof. | 2012-03-08 |
20120058225 | PROBIOTIC OIL SUSPENSION AND USE THEREOF - The present invention provides probiotic/oil suspension for vacuum infusion of an extruded probiotic food product characterized by balancing the requirements of a high concentration of the probiotic micro-organism in the suspension and physical properties that makes the suspension applicable for vacuum infusion. Further provided are methods of preparing said suspension and use thereof in the manufacture of an extruded probiotic food product. | 2012-03-08 |
20120058226 | BEVERAGE CARTRIDGE - A method, system and cartridge for forming a beverage includes a cartridge having a container defining an interior space, a lid, a filter, and a beverage medium contained in the interior space. The filter may be attached to the lid only, and extend into the interior space to separate first and second chambers of the cartridge. The filter may hold the beverage medium and be arranged so that, when the lid is removed from the container, e.g., by peeling the lid from the container, the filter and beverage medium are removed together with the lid. | 2012-03-08 |
20120058227 | Dog Chew Treats - A dog chew treat is fashioned from a composition comprising sugar, fiber, and flour. Preferably, the sugar is dextrose, and the flour is pre-gelatinized wheat flour. The composition may be molded into the shape of a bone, or other treat. A palatant coating may be applied to the molded product. Colors may be added for different aesthetics such as a marbling pattern. Functional ingredients may be used to provide health benefits. | 2012-03-08 |
20120058228 | CHOCOLATE COMPOSITION - A chocolate composition and a process for the manufacture of a chocolate composition. The chocolate composition comprises cocoa butter substitute/cocoa butter equivalent in combination with whey. In particular, the composition comprises 40-70 wt % sweetener, 25-30 wt % cocoa butter substitute (CBS) and/or cocoa butter equivalent (CBE), 4-10 wt % non-fat cocoa solids, milk solids and from 0-2 wt % cocoa butter, wherein at least 80 wt % of the milk solids are constituted by whey. | 2012-03-08 |
20120058229 | SYSTEMS AND METHODS FOR FACILITATING INTAKE OF EDIBLE SUBSTANCES - A system for facilitating a user's intake of edible substances. The system may include a first portion, a second portion, and a partition unit disposed between the first portion and the second portion. A first space may be located between the first portion and the partition unit for containing a first edible substance. A second space may be located between the second portion and the partition unit for containing a second edible substance. The system may also include a tube for causing a change at the partition unit to open an opening between the first space and the second space, and for transmitting a portion of an edible mixture to the mouth of the user. The edible mixture may include part of the first edible substance provided from the first space and part of the second edible substance provided from the second space. | 2012-03-08 |
20120058230 | METHOD AND A SYSTEM FOR PRESSURISING AND DISPENSING CARBONATED BEVERAGES - A self regulating and constant pressure maintaining beverage dispenser assembly comprises a dispensing device and a beverage container defining an inner space constituting a beverage space filled with carbonated beverage and communicating with the dispensing device for allowing dispensation of the carbonated beverage, and a head space communicating with the beverage space and filled with CO | 2012-03-08 |
20120058231 | Tubular Bag Packaging and Method for Producing Such Tubular Bag Packaging - A tubular bag packaging for bar-shaped food products is made of a film with first and second longitudinal edges. The film has a first seal section at the first longitudinal edge. A flap section at the second longitudinal edge has a second seal section along the second longitudinal edge. The film is closed at the seal sections by forming a continuous back seam in longitudinal direction as a fold-over seam. The film is sealed at transverse edges by transverse seams. The back seam has end face edges adjoining the transverse seams. The flap section has a linear separation cut as a tearing aid disposed on at least one of the end face edges and extending away from the end face edge in longitudinal direction. The film in the area of the second seal section with linear separating cut has a pressure deformation line that extends in longitudinal direction. | 2012-03-08 |
20120058232 | Method for the preparation of diacetyl tartaric acid esters of mono-and di-glycerides - The present invention provides a method for the preparation of diacetyl tartaric acid esters of mono- and di-glycerides, which comprises steps of: adding L-tartaric acid and/or DL-tartaric acid and acetic anhydride into a reaction kettle, adding concentrated phosphoric acid as catalyst and mixing together to form a reaction system; heating the reaction kettle until a temperature of the reaction system reaches 50° C.˜55° C. to initiate a reaction, after the temperature of the reaction system rises and then drops to 80° C.˜90° C., keeping the temperature at 80° C.˜90° C. for 20˜60 min to obtain an intermediate product; adding stearic acid esters of mono- and di-glycerides to the intermediate product, then adding powdery sodium hydroxide as catalyst, controlling an inner pressure of the reaction kettle at −0.09 Mpa˜−0.098 Mpa, heating the reaction kettle again until a temperature of the reaction system reaches 90° C.˜130° C., and keeping the temperature at 90° C.˜130° C. for 20˜40 min to obtain said diacetyl tartaric acid esters of mono- and di-glycerides. The preparation method according to the present invention has advantages of simple process, low production cost, high yield, good product quality and environmental friendliness. | 2012-03-08 |
20120058233 | METHOD OF PRODUCING PROCESSED TOMATO PRODUCT - A method is provided for producing a processed tomato product having more tomato aroma inherent to grown tomatoes. Tomato fruits are washed and crushed. Juice is extracted from the crushed material, the extracted juice is deaerated and the deaerated material is heated. The crushed material and the extracted juice from immediately after the crushing until immediately before the deaerating are maintained at temperature of 15-40° C. The dissolved oxygen concentration of the crushed tomatoes and/or the extracted juice from immediately after the crushing until immediately before the deaerating is raised at least temporarily to 6 mg/L or over, and the dissolved oxygen concentration of the deaerated juice immediately before the heating is reduced to 3.5 mg/L or below. | 2012-03-08 |
20120058234 | FOLDABLE COOKER - A device for food preparation. The device comprises: (a) a vertical support; (b) at least one arm characterized by a longitudinal axis. The arm is pivotally connected to the vertical support; (c) at least one cooker connected to of the arms, such that the plane of the at least one cooker is substantially parallel to the longitudinal axis of the arm. The device is characterized by two positions: (i) a FOLDED position; and, (ii) a horizontally OPERATIVE position; in the FOLDED position, the longitudinal axis of the arm is substantially parallel to the vertical support, and in the OPERATIVE position, the longitudinal axis of the arm is substantially perpendicular to the vertical support. The device is adapted to save space when the device is in the FOLDED position. | 2012-03-08 |
20120058235 | SEED OIL COMPOSITIONS - The present invention is directed to seed oil compositions that can be used for cooking and frying applications. These oil compositions of the present invention have advantageous stability characteristics. In some embodiments, the oil compositions have a low concentration of α-linolenic acid. | 2012-03-08 |
20120058236 | SWEETENER COMPOSITION COMPRISING HIGH SOLUBILITY FORM OF REBAUDIOSIDE A AND METHOD OF MAKING - Disclosed are sweetener compositions comprising rebaudioside A and methods of making the sweetener compositions. The sweetener compositions comprise a highly soluble crystal form of rebaudioside A that displays, in some embodiments, a solubility at 24° C. in water of about 25 (grams rebaudioside A/per 100 grams water) or greater. The high solubility of the sweetener composition of the invention allows it to be used in applications such as syrups and concentrates. | 2012-03-08 |
20120058237 | FOOD PROCESSING FOR AGRICULTURAL BIODIVERSITY - A formed food product including wild blueberry seeds and a method for producing such food product without damaging the wild blueberry germplasm such that seed viability is enhanced. The method contributes to the conservation and sustainable utilization of agricultural biodiversity. The formed food product is interspersed with seeds processed by way of the method to enable natural seed distribution in an edible manufactured food product. The formed food product, even after reaching its expiration date, provides seeds within it that are still be viable and can be extracted for future use. | 2012-03-08 |
20120058238 | METHOD FOR FLAVOR-TREATING FOODSTUFFS PROVIDED IN A PACKAGING - A method is disclosed for flavor-treating a food product ( | 2012-03-08 |
20120058239 | Stabilizer System for a Ready-to-Drink Whole Grain Beverage - A stabilizer system for use in a whole grain beverage containing carboxymethylcellulose (CMC), xanthan gum and gellan gum. In one aspect of the present invention, the stabilizer system includes about 5 to 20% gellan gum, about 1 to 10% xanthan gum, and about 50 to 90% CMC. The stabilizer system may be used in milk-based or juice-based whole grain beverages. | 2012-03-08 |