10th week of 2014 patent applcation highlights part 70 |
Patent application number | Title | Published |
20140066638 | NOVEL PROCESS FOR PREPARATION OF DARUNAVIR AND DARUNAVIR ETHANOLATE OF FINE PARTICLE SIZE - The present invention provides a novel process for preparation of darunavir that involves reduction of [(1S,2R)-3-[[(4-nitrophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]carbamic acid (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl ester, of formula (5). The present invention also provides darunavir ethanolate of particle size wherein d | 2014-03-06 |
20140066639 | OXIDATION PROCESS TO PRODUCE A CRUDE DRY CARBOXYLIC ACID PRODUCT - Disclosed is a process to produce a dry purified carboxylic acid product comprising furan-2,5-dicarboxylic acid (FDCA). The process comprises oxidizing at least one oxidizable compound selected from the following group: 5-(hydroxymethyl)furfural (5-HMF), 5-HMF esters (5-R(CO)OCH | 2014-03-06 |
20140066640 | DIRECT TRIFLUOROMETHYLATIONS USING TRIFLUOROMETHANE - A direct trifluoromethylation method preferably using a trifluoromethane as a fluoro-methylating species. In particular, the present method is used for preparing a trifluoromethylated substrate by reacting a fluoromethylatable substrate with a trifiuoromethylating agent in the presence of an alkoxide or metal salt of silazane under conditions sufficient to trifluoromethylate the substrate; wherein the fluoromethylatable substrate includes chlorosilanes, carbonyl compounds such as esters, aryl halides, aldehydes, ketones, chalcones, alkyl formates, alkyl halides, aryl halides, alkyl borates, carbon dioxide or sulfur. | 2014-03-06 |
20140066641 | METHOD FOR PREPARING 5-CHLOROMETHYL-2-FURFURAL USING GALACTAN DERIVED FROM SEAWEED IN TWO COMPONENT PHASE - The present disclosure relates to an acid catalyst composition for producing 5-chloromethyl-2-furfural from galactan derived from seaweed and a method for producing 5-chloromethyl-2-furfural from galactan derived from seaweed on a two component phase using the acid catalyst, the acid catalyst composition for producing 5-chloromethyl-2-furfural from galactan derived from seaweed including organic solvent and dilute hydrochloric acid, a concentration of the dilute hydrochloric acid being 4N to 8N (normal). | 2014-03-06 |
20140066642 | METHOD OF SYNTHESIS OF SUBSTITUTED HEXITOLS SUCH AS DIANHYDROGALACTITOL - The present invention provides an efficient method of synthesizing and purifying dianhydrohexitols such as dianhydrogalactitol. In general, as applied to dianhydrogalactitol, the method comprises: (1) reacting dulcitol with a concentrated solution of hydrobromic acid at a temperature of about 80° C. to produce dibromogalactitol; (2) reacting the dibromogalactitol with potassium carbonate in t-butanol to produce dianhydrogalactitol; and (3) purifying the dianhydrogalactitol using a slurry of ethyl ether to produce purified dianhydrogalactitol. Another method produces dianhydrogalactitol from dulcitol; this method comprises: (1) reacting dulcitol with a reactant to convert the 1,6-hydroxy groups of dulcitol to an effective leaving group to generate an intermediate; and (2) reacting the intermediate with an inorganic weak base to produce dianhydrogalactitol through an intramolecular S | 2014-03-06 |
20140066643 | ALS INHIBITOR HERBICIDE TOLERANT B NAPUS MUTANTS - The present invention relates to an ALS inhibitor herbicide tolerant | 2014-03-06 |
20140066644 | METHOD FOR PRODUCING OIL CONTAINING HIGHLY UNSATURATED FATTY ACID USING LIPASE - A method for lowering content of a sterol in a highly unsaturated fatty acid-concentrated oil in a method to concentrate a highly unsaturated fatty acid by using a lipase reaction, may include removing the free form of the sterol from a raw material oil that includes a highly unsaturated fatty acid-containing glyceride prior to performing the lipase reaction; and thereafter concentrating the highly unsaturated fatty acid in the glyceride by using a lipase that is less reactive for the highly unsaturated fatty acid. | 2014-03-06 |
20140066645 | POLYLACTIDE RESIN AND PREPARATION METHOD THEREOF - The present invention is directed to an organometallic complex and a catalyst composition capable of producing polylactide resins with improved properties at a higher conversion rate, a method of producing the organometallic complex, polylactide resins having enhanced hydrolysis resistance and heat resistance together with superior mechanical properties, a preparation process therefor, and polylactide resin compositions including the same. | 2014-03-06 |
20140066646 | 1,3,2-Dioxaphosphorinane, 2-Sulfide Derivatives For Use As Anti-Wear Additives In Lubricant Compositions - The present disclosure relates to a non-acidic, sulfur-containing, phosphorus-containing compound of the formula I | 2014-03-06 |
20140066647 | METHOD FOR SYNTHESIS OF [6,6]-PHENYL-C61-BUTYRIC ACID METHYL ESTER (PCBM) AND FULLERENE DERIVATIVES - The present subject matter relates to methods for the synthesis of [6,6]-phenyl-C | 2014-03-06 |
20140066648 | AMINO ACID DERIVATIVES USED AS PHARMACEUTICAL SUBSTANCES - The invention relates to a method for improving bioavailability of pharmaceutical substances and for allowing the pharmaceutical substances to permeate the blood-brain barrier, the pharmaceutical substances having at least one or more amidine, guanidine, N-hydroxyamidine (amidoxime) or N-hydroxyguanidine functions. The invention also relates to medicaments containing the correspondingly modified pharmaceutical substances. | 2014-03-06 |
20140066649 | Process for Producing Vinyl Acetate - The present invention relates to a process for forming vinyl acetate. The process comprises the step of providing a reaction mixture having an initial heat capacity. The reaction mixture comprises acetic acid, oxygen, ethylene, and optionally water. The process further comprises the step of adding to the reaction mixture at least one heat capacity modifier to form an increased heat capacity reaction mixture. The process further comprises the step of contacting the acetic acid, oxygen, and ethylene over a catalyst under conditions effective to form a crude vinyl acetate product. The crude vinyl acetate product comprises vinyl acetate and water. | 2014-03-06 |
20140066650 | Process for Vinyl Acetate Production Having Sidecar Reactor for Predehydrating Column - A process for producing vinyl acetate in which a secondary reactant stream is obtained from a predehydrating column and reacted in a sidecar reactor to further increase conversion of ethylene, acetic acid, and molecular oxygen and increase production of vinyl acetate. | 2014-03-06 |
20140066651 | PROCESS FOR PRODUCING AN ACRYLATE PRODUCT - In one embodiment, the invention is to a process for producing an acrylate product. The process comprises the step of reacting in a reactor a reaction mixture comprising alkanoic acid and an alkylenating agent under conditions effective to form a crude acrylate product. The process further comprises the step of separating at least a portion of the crude acrylate product to recover a finished acrylate product. The reaction is conducted at a reaction pressure less than 120 kPa. | 2014-03-06 |
20140066652 | PROCESS FOR PRODUCING (METH)ACRYLIC ACID - A process for producing (meth)acrylic acid comprising the step of repeating a crystallization operation “n” times to produce purified (meth)acrylic acid from crude (meth)acrylic acid, wherein: the each crystallization operation comprises a crystallizing step and a melting step; a polymerization inhibitor is not added to a (meth)acrylic acid melt obtained in the melting step of the first to n−1 | 2014-03-06 |
20140066653 | Processes For Purifying Acetic Anhydride and Method of Making Same - In one embodiment, the invention is to a process for purifying acetic anhydride. The process includes the steps of feeding a liquid crude acetic anhydride stream directly to a distillation column and separating the liquid crude acetic anhydride stream to produce a light ends stream, a sidedraw and a residue stream. The sidedraw comprises substantially pure acetic anhydride product. The distillation column is operated at a pressure less than 101 kPa. The substantially pure acetic anhydride product comprises greater than 98 wt. % acetic anhydride, has a permanganate time of greater than 10 minutes, and has an APHA color of less than 10. | 2014-03-06 |
20140066654 | Solvent-Free Process for the Preparation of Cyclophosphamide - This invention discloses a solvent-free process for the preparation of cyclophosphamide. According to this invention, there is no solvent used during the reaction step for preparing cyclophosphamide, so that the total volume of the reaction for preparing cyclophosphamide can be reduced and the manufacture of cyclophosphamide can become more efficient. Furthermore, the above solvent-free process for the preparation of cyclophosphamide is more simply operated, more economic, and more environmental friendly than the preparation of cyclophosphamide in the prior art. | 2014-03-06 |
20140066655 | PROCESS FOR PREPARING N-H OR N-ALKYL 2-PROPYNAMIDE - Disclosed is a method for the synthesis of N—H or N-alkyl 2-propynamides useful as intermediate in the manufacture of pharmaceutically active ingredients. | 2014-03-06 |
20140066656 | SPIRO COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS APPLICATIONS AND DEVICES - The present invention relates 9,9′-spirobifluorene compounds of general formula I | 2014-03-06 |
20140066657 | DOSAGE REGIMEN FOR A S1P RECEPTOR AGONIST - S1P receptor modulators or agonists are administered following a dosage regimen whereby during the initial days of treatment the daily dosage is lower than the standard daily dosage | 2014-03-06 |
20140066658 | Method for Hydrogenating Nitroaromatic Systems with Selected Platinum Catalysts - A method is described for the catalytic hydrogenation of aromatic nitro compounds with hydrogen to the corresponding amines in the presence of a supported catalyst comprising platinum. The method is characterized in that the catalyst comprising platinum has been modified with a tungsten compound and with a phosphorus compound in an oxidation state of <5. High yields and high selectivities are possible with the method. | 2014-03-06 |
20140066659 | Bis(Trifluoromethanesulfonyl)Ethyl-Bearing Compound and Acid Catalyst, and Method for Preparing Same - A bis(trifluoromethanesulfonyl)ethyl group-bearing compound represented by the following formula [1], [2] or [3] | 2014-03-06 |
20140066660 | Method for Producing Dialkoxy Alkanes by Partial Oxidation of Lower Alcohols in the Presence of a Catalyst Based on Molybdenum and Iron - Disclosed herein is a method for producing alkoxy alkanes by direct partial oxidation of a lower alcohol with a catalyst based upon mixed oxide containing molybdenum and at least one other metal selected from the metals that can assume a trivalent oxidation state such as Fe, Bi, Al, Cr, In, La, Sb, and/or a metal selected from Ni, Co, Cu, V, W, Ti, Ta, Nb, Mn, Sn, P. | 2014-03-06 |
20140066661 | CYCLOPOLYARYLENE COMPOUND AND METHOD OF MANUFACTURING SAME - A cyclopolyarylene compound represented by Formula (1): | 2014-03-06 |
20140066662 | PROCESS FOR THE PREPARATION OF BRONOPOL - The invention provides a process for preparing bronopol, which process comprises charging a reaction vessel with water, bromopicrin, nitromethane and paraformaldehyde, gradually feeding a base into said reaction vessel under stirring, bringing the reaction to completion and separating bronopol from the aqueous reaction mixture. | 2014-03-06 |
20140066663 | Dehydrogenation Catalyst and Process - A catalyst composition comprises (i) a support; (ii) a dehydrogenation component comprising at least one metal or compound thereof selected from Groups 6 to 10 of the Periodic Table of Elements; and (iii) tin or a tin compound, wherein the tin is present in an amount of 0.01 wt % to about 0.25 wt %, the wt % based upon the total weight of the catalyst composition. | 2014-03-06 |
20140066664 | PROCESS FOR THE PREPARATION OF MENTHOL - The invention relates to a process for the preparation of 2-isopropyl-5-methylcyclohexanol (menthol) via the hydrogenation of thymol to neomenthol and the subsequent isomerization to give D/L (+/−)-menthol. | 2014-03-06 |
20140066665 | PROCESS FOR THE PREPARATION OF MENTHOL - The invention relates to a process for the preparation of 2-isopropyl-5-methylcyclohexanol (D,L-menthol) via the hydrogenation of thymol to menthone and subsequent further hydrogenation to give D,L-menthol. | 2014-03-06 |
20140066666 | Method For Producing 1,2-Pentanediol - A process for the preparation of 1,2-pentanediol by reaction of a starting material comprising one or both compounds from the group consisting of furfuryl alcohol and furfural with hydrogen in the presence of a first heterogeneous catalyst is described. | 2014-03-06 |
20140066667 | OLEFIN HYDRATION PROCESS USING OSCILLATORY BAFFLED REACTOR - A butanol production system and method of producing refined mixed butanols from water and mixed butenes. The system includes an internal baffle single pass reactor, a separation system and an exterior motion driver. The reactor has baffled cells. The separations system is operable to separately selectively separate water and mixed butenes from the crude product such that a refined mixed butanols is produced. The exterior motion driver is operable to induce unsteadiness in the fluid flow of the process fluid through the reactor. A method for producing refined mixed butanols includes introducing mixed butenes, water and a butene hydration catalyst into the reactor, operating the butanol production system such that the external motion driver induces unsteadiness in the process fluid flow and the reaction of mixed butenes and water occurs in the presence of the butene hydration catalyst such that mixed butanols form. | 2014-03-06 |
20140066668 | METHOD AND APPARATUS FOR PROCESSING GLYCOL - Methods and apparatus for processing glycol according to various aspects of the present technology comprise a multi-stage treatment system that is configured to receive a feedstock from multiple waste stream sources containing glycol. A pre-treatment stage may be configured to process the incoming the feedstock and provide to a primary treatment stage a water/glycol solution that is substantially identical and allows for a primary treatment process that is not dependent upon the originating source of the glycol feedstock. A post-treatment stage may further process and purify the water/glycol solution. | 2014-03-06 |
20140066669 | ENERGY EFFICIENT METHOD AND APPARATUS FOR THE EXTRACTION OF LOWER ALCOHOLS FROM DILUTE AQUEOUS SOLUTION - The present invention relates to the energy efficient and selective extraction of dilute concentrations of C2-C6 alcohols from an aqueous solution using liquid phase dimethyl ether. | 2014-03-06 |
20140066670 | REACTOR AND AGITATOR USEFUL IN A PROCESS FOR MAKING 1-CHLORO-3,3,3-TRIFLUOROPROPENE - Disclosed is a reactor and agitator useful in a high pressure process for making 1-chloro-3,3,3-trifluoropropene (1233zd) from the reaction of 1,1,1,3,3-pentachloropropane (240fa) and HF, wherein the agitator includes one or more of the following design improvements:
| 2014-03-06 |
20140066671 | Renewable Engine Fuel And Method Of Producing Same - The present invention provides high-octane fuel, and a method of producing same. These fuels may be formulated to have a wide range of octane values and energy, and may effectively be used to replace 100 LL aviation fuel (known as AvGas), as well as high-octane, rocket, diesel, turbine engine fuels, as well as two-cycle, spark-ignited engine fuels. | 2014-03-06 |
20140066672 | METHOD FOR PRODUCING SINGLE-RING AROMATIC HYDROCARBONS - Provided is a method for producing monocyclic aromatic hydrocarbons having 6 to 8 carbon atoms, the method including a cracking reforming reaction step of bringing feedstock oil into contact with a catalyst to effect a reaction; a step of purifying and recovering monocyclic aromatic hydrocarbons separated from the reaction step; and (1) a step of hydrogenating a heavy fraction separated from the reaction step; a dilution step of returning a portion of the hydrogenation product as a diluent oil to the hydrogenation step; and a step of returning the hydrogenation product to the reaction step; or (2) a step of adding a diluent to the heavy fraction separated from the reaction step; a step of hydrogenating the mixture; and a step of returning the hydrogenation product to the reaction step. | 2014-03-06 |
20140066673 | METHOD FOR PRODUCING MONOCYCLIC AROMATIC HYDROCARBONS - A method for producing monocyclic aromatic hydrocarbons includes a cracking reforming reaction step of bringing an oil feedstock into contact with a catalyst for monocyclic aromatic hydrocarbon production containing a crystalline aluminosilicate, and causing the oil feedstock to react, thereby obtaining a product containing monocyclic aromatic hydrocarbons having 6 to 8 carbon atoms, a hydrogenation reaction step of hydrogenating a product produced in the cracking reforming reaction step, a monocyclic aromatic hydrocarbon recovery step of recovering monocyclic aromatic hydrocarbons having 6 to 8 carbon atoms separated from a hydrogenation product obtained in the hydrogenation reaction step and a recycling step of returning a heavy fraction having 9 or more carbon atoms separated from the hydrogenation product obtained in the hydrogenation reaction step to the cracking reforming reaction step. | 2014-03-06 |
20140066674 | UZM-39 ALUMINOSILICATE ZEOLITE - A new family of coherently grown composites of TUN and IMF zeotypes have been synthesized. These zeolites are represented by the empirical formula. | 2014-03-06 |
20140066675 | Xylene Isomerization Process and Catalyst Therefor - The invention concerns a xylenes isomerization process for the production of equilibrium or near-equilibrium xylenes from a feedstream comprising phenol and/or styrene. | 2014-03-06 |
20140066676 | Catalytic Reforming - Methods and systems for improved catalytic reforming are disclosed. A method of catalytic reforming includes feeding a feedstream comprising C | 2014-03-06 |
20140066677 | Process for the Oxidative Coupling of Hydrocarbons - A method for the oxidative coupling of hydrocarbons, such as the oxidative coupling of methane to toluene, includes providing an oxidative catalyst inside a reactor, and carrying out the oxidative coupling reaction under a set of reaction conditions. The oxidative catalyst includes (A) at least one element selected from the group consisting of the Lanthanoid group, Mg, Ca, and the elements of Group 4 of the periodic table (Ti, Zr, and Hf); (B) at least one element selected from the group consisting of the Group 1 elements of Li, Na, K, Rb, Cs, and the elements of Group 3 (including La and Ac) and Groups 5-15 of the periodic table; (C) at least one element selected from the group consisting of the Group 1 elements of Li, Na, K, Rb, Cs, and the elements Ca, Sr, and Ba; and (D) oxygen. | 2014-03-06 |
20140066678 | ALKYLATION PROCESS WITH RECYLE OF HYDROGEN AND RECOVERY OF HYDROGEN CHLORIDE - We provide processes, and process units for practicing the processes, comprising
| 2014-03-06 |
20140066679 | METHOD OF MAKING DIETHYLBENZENE - The method of making diethylbenzene selectively produces diethylbenzene by reacting ethyibenzene and ethanol over a zeolite catalyst, such as ZSM-5. The zeolite catalyst is first heated in argon gas within a reaction chamber. The zeolite catalyst is then selectively coked with a precursor mixture of ethylbenzene and ethanol. Argon gas is then flowed over the coked zeolite catalyst, and a reaction mixture of ethylbenzene and ethanol is injected into the reaction chamber to produce diethylbenzene, which is then removed from within the reaction chamber. | 2014-03-06 |
20140066680 | CATALYST FOR THE OXIDATIVE DEHYDROGENATION OF BUTENE TO BUTADIENE AND PREPARATION PROCESS THEREOF - The present disclosure provides a catalyst for oxidative dehydrogenation of butene to butadiene, comprising at least one compound of formula Zn | 2014-03-06 |
20140066681 | CATALYST FOR METATHESIS OF ETHYLENE AND 2-BUTENE AND/OR DOUBLE BOND ISOMERIZATION - A process for the double-bond isomerization of olefins is disclosed. The process may include contacting a fluid stream comprising olefins with a fixed bed comprising an activated basic metal oxide isomerization catalyst to convert at least a portion of the olefin to its isomer. The isomerization catalysts disclosed herein may have a reduced cycle to cycle deactivation as compared to conventional catalysts, thus maintaining higher activity over the complete catalyst life cycle. | 2014-03-06 |
20140066682 | PROCESS AND APPARATUS FOR EXTRACTING SULFUR COMPOUNDS IN A HYDROCARBON STREAM - One exemplary embodiment can be a process for extracting sulfur compounds in a hydrocarbon stream. The process can include feeding a hydrocarbon stream containing sulfur compounds to a prewash zone containing an alkali, withdrawing a prewashed hydrocarbon stream from the prewash zone, and feeding the prewashed hydrocarbon stream to a mass transfer zone for extracting one or more thiol compounds from the prewashed hydrocarbon stream. Often, the mass transfer zone includes a hollow fiber membrane contactor. | 2014-03-06 |
20140066683 | Process, Method, and System for Removing Heavy Metals from Fluids - A method for concurrently transporting and removing trace amount levels of heavy metals such as mercury from produced fluids such as natural gas, with the injection of a complexing agent and a hydrate inhibitor into the pipeline for use in transporting the produced fluid. Volatile mercury in the natural gas is removed while the produced fluid is being transported in the pipeline, with the hydrate inhibitor suppressing or decreasing the formation of the hydrate that would cause plugging in the pipeline. The complexing agent reacts with the volatile mercury in the natural gas, forming precipitate or soluble mercury complexes in the aqueous phase. The aqueous phase containing the hydrate inhibitor, unreacted complexing agent, and mercury complexes is subsequently recovered and can be re-used in the pipeline. | 2014-03-06 |
20140066684 | MITIGATION OF SECONDARY PHASE FORMATION DURING WASTE VITRIFICATION - A method for vitrification of waste to reduce the formation of persistent secondary phases comprising separating at least one glass frit constituent from an initial glass frit to form a modified glass frit. The waste, modified glass frit, and the at least one glass frit constituent are mixed together with the modified glass frit and the at least one glass frit constituent being added as separate components. The resulting mixture is vitrified. | 2014-03-06 |
20140066685 | METHOD FOR DISPOSAL OF RADIOACTIVE WASTE - Provided is a method for disposal of radioactive waste which can reduce the radiation level until the waste can be reused as landfill or the like and which prevents the leakage of radiation nuclides in the ground. The method includes the following: a primary treatment step of turning the radioactive waste into a radioactive waste (primary treated waste) which has a radiation level equal to or less than a reference value via a radiation shielding agent composed of or predominantly composed of a Ca-based inorganic compound; and a secondary treatment step of heating to melt the primary treated waste and thereafter cooling the same to glass granules, and then sealing radioactive nuclides in the glass body. | 2014-03-06 |
20140066686 | TREATMENT OF WASTE - The present invention provides a method for the treatment of waste comprising one or more hazardous organic components, the method comprising plasma treating a waste in a plasma treatment unit; wherein the waste comprises: (i) a soil and/or aggregate material; and (ii) an oil component; and wherein, before plasma treating the waste, the waste comprises one or more hazardous organic components and from 5 to 50% water by weight of the waste. | 2014-03-06 |
20140066687 | RADIATION THERAPY OF PROTRUDING AND/OR CONFORMABLE ORGANS - A system provided for delivering Accelerated Partial Breast Irradiation (APBI) and for delivering a boost to standard whole-breast irradiation (WBI) for the treatment of breast cancer that significantly reduces the risks of adverse cosmetic outcomes and toxicities. This is achieved by a method and device for delivering a uniform radiation dose to the target volume with significantly reduced dose to the non-target volume, skin and chest wall of the ipsilateral breast, and virtually no dose to the contralateral breast, lungs, and heart. | 2014-03-06 |
20140066688 | BRACHYTHERAPY AND BUTTRESS ELEMENT CO-DELIVERY - Brachytherapy delivery devices and buttress elements are described herein, along with methods of assembling the brachytherapy devices and the buttress elements for co-delivery of the brachytherapy delivery devices and buttress elements are described herein. | 2014-03-06 |
20140066689 | Integrated Controller For Ventricular Assist Device - An integrated control module is provided for a ventricular assist device. A housing receives a power monitoring/switching circuit, a main receptacle, and a quasi-internal backup receptacle. The main receptacle within the housing receives a main battery. The main receptacle is configured for manual installation and removal of the main battery without requiring any separate tool. The quasi-internal backup receptacle within the housing receives a backup battery having a battery capacity less than the main battery. The backup receptacle includes a locking mechanism that requires use of a separate tool to unlock the locking mechanism for removing the backup battery. The backup battery is installed and removed without disturbing power supplied from a main battery in the main receptacle to the power monitoring/switching circuit. | 2014-03-06 |
20140066690 | Start-up Algorithm for an Implantable Blood Pump - A system and a method for starting a rotor of an implantable blood pump are described. For example, a blood pump system includes a rotary motor having a stator and a rotor. The rotor has permanent magnetic poles for magnetic levitation of the rotor, and the stator has a plurality of pole pieces arranged circumferentially at intervals. The blood pump system includes a controller configured to control a start phase of the rotor, wherein the start phase is prior to the rotor being positioned in a predefined geometric volume for pumping blood and wherein the start phase includes performing a rotation of the rotor by an angle larger than an angle corresponding to a quarter of an angular distance between two neighboring magnetic poles of the rotor. | 2014-03-06 |
20140066691 | Instability Detection Algorithm for an Implantable Blood Pump - An instability detection algorithm for an implantable blood pump may include determining a target position of a rotor of the pump, the rotor having permanent magnetic poles for magnetic levitation of the rotor, calculating a positional displacement of the target position from a predefined origin of a coordinate system of a housing of the pump, and calculating, during a rotation of the rotor, geometric deviations of a current position of the rotor from the target position. | 2014-03-06 |
20140066692 | BABY BLANKET - An amniotic infant blanket provides a feeling of fluid warmth coupled with the audible sounds of a human heartbeat. Behind a head or face portion of the blanket, a pocket is provided into which a bladder may be removably inserted. The pocket may be sealed by a zipper and has an aperture through which a hydrophone wire may pass. Likewise, the hydrophone wire may pass through the wall of the bladder without creating a leak therethrough. The bladder is filled with lukewarm tap water and the hydrophone connected to a playback unit that transmits signals that are transformed by the hydrophone into heartbeat sounds with which the infant is familiar. | 2014-03-06 |
20140066693 | METHODS AND DEVICES FOR TISSUE GRASPING AND ASSESSMENT - Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation. | 2014-03-06 |
20140066694 | IMMOBILIZED BIOACTIVE HYDROGEL MATRICES AS SURFACE COATINGS - The present invention is directed to a stabilized bioactive hydrogel matrix coating for substrates, such as medical devices. The invention provides a coated substrate comprising a substrate having a surface, and a bioactive hydrogel matrix layer overlying the surface of the medical device, the hydrogel matrix comprising a first high molecular weight component and a second high molecular weight component, the first and second high molecular weight components each being selected from the group consisting of polyglycans and polypeptides, wherein at least one of the first and second high molecular weight components is immobilized (e.g., by covalent cross-linking) to the surface of the substrate. | 2014-03-06 |
20140066695 | MAGNARETRACTOR SYSTEM AND METHOD - A system and method for performing surgical procedures within a body cavity, e.g. abdomen, uses a magnetized device is utilized to allow a surgeon to control intra-abdominal organs and objects. The system and method allows a surgeon to perform an intra-abdominal procedure without the need to position surgical tools inside of the body cavity. Additional surgical ports are not necessary as the magnetized device allows the surgeon to retract or position various objects within the abdomen. | 2014-03-06 |
20140066696 | METHOD AND SYSTEM FOR DETERMINING THE PRESSURE OF A FLUID IN A SYRINGE, AN ACCESS PORT, A CATHETER, AND A GASTRIC BAND - A method and system for determining pressure in a syringe, and more specifically to a syringe pressure accessory which can be connected to a syringe to determine pressure in a syringe and a gastric band. The syringe pressure accessory can detect a pressure of a syringe and/or a gastric band and digitally display the pressure. The syringe pressure accessory can include a durable unit and a disposable unit. The disposable unit can be disposed of after a single use, while the durable unit can be reused with multiple disposable units. The syringe pressure accessory can also include a syringe attachment unit and one or more display units for a caretaker or a patient. The display unit can be wirelessly connected to the syringe attachment unit to display a pressure chart or the results of various analysis of the pressure data. Markers can be added to the pressure chart. | 2014-03-06 |
20140066697 | IMPLANTABLE DEVICE TO PROTECT TUBING FROM PUNCTURE - An implantable device used in a gastric band system includes an access port, a tube coupled to the access port, and a shielding device covering a portion of the tube. The shielding device is positioned adjacent to the access port and covers the end of the tube coupled to the access port. The shielding device is made from a puncture resistant material, to protect the tube from puncture by a misplaced syringe needle inserted by a physician. | 2014-03-06 |
20140066700 | Stereoscopic System for Minimally Invasive Surgery Visualization - Embodiments of the present invention provide improved visualization systems and methods for minimally invasive surgery. Some embodiments include the use of reverse kinematic positioning of camera systems to provide rapid and manual surgeon controllable positioning of camera systems as well as display of 3D surgical area images along the line of sight between a surgeon's eyes and the surgical area itself. | 2014-03-06 |
20140066701 | METHOD FOR MINIMALLY INVASIVE SURGERY STEROSCOPIC VISUALIZATION - Aspects of the present invention provide improved visualization systems and methods for minimally invasive surgery. Some embodiments include the use of reverse kinematic positioning of camera systems to provide rapid and manual surgeon controllable positioning of camera systems as well as display of 3D surgical area images along the line of sight between a surgeon's eyes and the surgical area itself. | 2014-03-06 |
20140066702 | SURGICAL IMAGING DEVICE - A surgical imaging device and method configured to be inserted into a surgical site. The surgical imaging device includes a plurality of prongs. Each one of the prongs has an image sensor mounted thereon. The image sensors provide different image data corresponding to the surgical site, thus enabling a surgeon to view a surgical site from several different angles. The prongs may be moveable between a first position, suitable for insertion through a small surgical incision, and a second position, in which the prongs are separated from each other. In addition, the prongs may be bendable. | 2014-03-06 |
20140066703 | STEREOSCOPIC SYSTEM FOR MINIMALLY INVASIVE SURGERY VISUALIZATION - Embodiments of the invention are directed to minimally invasive surgical instruments and procedures using those instruments wherein the instruments include optical elements (e.g. a percutaneous optical channel (POC), a retaining plug and a stereoscopic imaging device (e.g. a stereoscopic camera) and a stereoscopic display device. The instruments be part of a system used to provide a surgeon with an indirect stereoscopic view of a surgical area undergoing a minimally invasive surgical procedure in a way that is perceived by the surgeon as being similar to that of an open surgery and providing a natural and intuitive environment to perform the surgery with a high degree of control. | 2014-03-06 |
20140066704 | STEREOSCOPIC METHOD FOR MINIMALLY INVASIVE SURGERY VISUALIZATION - Embodiments of the invention are directed to minimally invasive surgical instruments and procedures using those instruments wherein the instruments include optical elements (e.g. a percutaneous optical channel (POC), a retaining plug and a stereoscopic imaging device (e.g. a stereoscopic camera) and a stereoscopic display device. The instruments be part of a system used to provide a surgeon with an indirect stereoscopic view of a surgical area undergoing a minimally invasive surgical procedure in a way that is perceived by the surgeon as being similar to that of an open surgery and providing a natural and intuitive environment to perform the surgery with a high degree of control. | 2014-03-06 |
20140066705 | ENDOSCOPE INCLUING A MULTIFUNCTION CONDUCTOR - In one embodiment, an endoscope includes an elongate member having a proximal end portion and a distal end portion. The distal end portion is configured to be inserted into a body lumen. An electrical component is disposed within the distal end portion of the elongate member and configured to produce a signal. An elongate conductive mechanical component has a proximal end portion and a distal and portion. The distal end portion of the elongate conductive mechanical component is electrically coupled to the electrical component and configured to conduct the signal or electrical power from/to the electrical component to/from the proximal end portion of the elongate conductive mechanical component. | 2014-03-06 |
20140066706 | IN-VIVO VISUALIZATION SYSTEM - Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree. | 2014-03-06 |
20140066707 | LIFTING CAP - An endoscope procedure instrument provided with: a tube part that is cylindrical in shape and attaches to the front end of the endoscope, the tube part having a slit provided to the side surface thereof extending along the direction of the central axis; and a grasping member that is disposed to the tube part extending along the slit, for holding a biologic tissue with respect to the endoscope. | 2014-03-06 |
20140066708 | ENDOSCOPE CAP FOR CATHETER DEPLOYMENT - A surgical system is provided that includes a sleeve having an inner surface defining a first channel that extends along a first longitudinal axis and an inner surface defining a second channel that extends along a second longitudinal axis. The second channel is spaced apart from the first channel. A first surgical instrument is configured for disposal in the first channel. The first surgical instrument includes an optical probe configured for imaging. A second surgical instrument is configured for disposal in the second channel. The second surgical instrument includes an inflatable balloon. Methods and kits are also provided. | 2014-03-06 |
20140066709 | COMPACT ENDOSCOPIC SURGICAL BLADE ASSEMBLY AND METHOD OF USE THEREOF - An endoscopic surgical device having a slotted clear cannula, a blade and a housing, wherein the cannula is attached to the housing, and wherein the blade is enclosed in the housing and is slidable into the cannula is disclosed. The blade is enclosed within the housing and cannula, and has a horizontally-oriented pushing component and a vertically-oriented cutting component that protrudes through the slot of the cannula. The device further has a device for locking a viewing device in place relative to other components of the device. A method for a performing an operative procedure on a target tissue in a subject using the endoscopic surgical device is also described. | 2014-03-06 |
20140066710 | DEVICES AND METHODS FOR INTRAOPERATIVE CONTROL OF ENDOSCOPIC IMAGING - An endoscopic imaging system including a rigid endoscope, a housing, a user input assembly, control circuitry, an actuator, and a position sensor. The endoscope defines a centrifugal bore and has a longitudinal axis, a proximal end portion, and a distal end portion. The endoscope includes a lens assembly positioned within the centrifugal bore. The housing of the device has an internal compartment and is securely coupled to the proximal end portion of the endoscope. Optical coupling for light is provided which allows for unlimited rotation and provides for improved image stability. The user input assembly receives user input controls corresponding to a selected rotational position of the endoscope. The control circuitry receives the user input controls and transmits them to the actuator, which controllably rotates the endoscope about the longitudinal axis of the endoscope in response to the user input controls. The position sensor produces a position signal indicative of the rotational position of the endoscope. The control circuitry uses the position signal to determine the required axial rotation of the endoscope. | 2014-03-06 |
20140066711 | LAPAROSCOPE SYSTEM - A visual system for laparoscopy comprising a visual device having a visual head member and an elongated connector; a manipulation device having a handheld operation portion, an insertion portion and a first contact element; and an external device comprising means to communicate with the vision head member, via the first contact element, when the elongated connector is mounted in an lumen of the insertion portion. The insertion portion of the manipulation device is configured to be extendable out from a body cavity through an airtight passage whereby the elongated connector is configured to be slidably mounted into the lumen of the insertion portion outside of the body cavity upon the insertion portion is withdrawn into the body cavity. | 2014-03-06 |
20140066712 | ENDOSCOPE WITH DISTAL TIP HAVING ENCASED OPTICAL COMPONENTS AND DISPLAY ORIENTATION CAPABILITIES - An apparatus according to one embodiment includes an endoscope tip including a housing that is monolithically formed of a transparent material. At least one optical component is at least partially encased within the housing. The optical component can be, for example, a light source, a fiber optic, an imaging sensor, a lens, a reflector or a light shield. In another embodiment, an apparatus includes an endoscope having a distal end portion that includes a housing. The housing is monolithically formed with a transparent material and a light source is at least partially encased within the housing. The housing also includes a micro-defects portion within the transparent material of the housing. The micro-defects portion is configured to provide a selected output shape of a beam of light produced by the light source. | 2014-03-06 |
20140066713 | INSERTION DEVICE, ROTATING TUBULAR MEMBER, AND DRIVING UNIT - An insertion device includes a channel defining portion extended through an inside of an insertion section up to a base portion toward a distal direction and defining a channel that is open to an outside of the insertion section in an opening of an outer peripheral portion of the base portion, and a driving unit extended through an inside of the channel with a driving axis being an axial center and being rotatable in directions around the driving axis when driven. The insertion device includes a driving force receiving portion connected to a gear portion in the opening of the channel, and a support unit supporting the driving unit so that the driving axis is parallel to the longitudinal axis in the gear portion. | 2014-03-06 |
20140066714 | ENDOSCOPY SYSTEMS - Preparing an endoscope insertion assembly for performing endoscopy by providing the endoscope insertion assembly including an endoscope insertion tube operative for passage through a body cavity, and an optical assembly operative for inspection of said body cavity, and selectably inserting the optical assembly within said endoscope insertion tube. | 2014-03-06 |
20140066715 | HARNESS FOR MEDICAL DEVICE AND METHOD FOR ASSEMBLING MEDICAL DEVICE - A harness for a medical device is provided which can suppress defective products from being passed to the subsequent process. The harness | 2014-03-06 |
20140066716 | INSERTION APPARATUS - An insertion portion, a bending portion, an inner guide sheath, an operation portion, a fixing lever, a guide member, a crank member, a pair of link members, and cam members that are rotatable to a second rotation position where the cam members simultaneously press exposed sites of moving members to wall surfaces in a vertical direction, and a first rotation position where the cam members are separated from the exposed sites, by either one of opening and closing of the respective link members are included. | 2014-03-06 |
20140066717 | SURGICAL PORT FEATURE - A surgical port feature may include a funnel portion, a tongue, a waist portion, and surgical instrument channels. The waist portion may be located between the funnel portion and the tongue. The surgical instrument channels may extend from the funnel portion through the waist portion. The surgical port feature may further include a second tongue, with the wait portion being located between the funnel portion, the tongue, and the second tongue. | 2014-03-06 |
20140066718 | SURGICAL DEVICE FOR MINIMALLY INVASIVE SPINAL FUSION AND SURGICAL SYSTEM COMPRISING THE SAME - A surgical device is disclosed which may advantageously perform the functions of both a retractor and a distractor. The device has two retractor blades facing each other and held in a common frame, the retractor blades are insertable into a surgical incision in a patient and moveable away from each other along a main axis (x) so as to widen the surgical incision; and a connecting pin attached at a distal end of each retractor blade. Each connecting pin is attachable to a pedicle screw anchored to respective vertebrae of the patient, so that moving away the two retractor blades along the main axis (x) determines a distraction of the vertebrae. | 2014-03-06 |
20140066719 | SURGICAL RETRACTOR AND METHOD OF USE - A surgical retractor comprises a first member extending between a first end and a second end including at least one first fixation element. A second member includes a blade and a biasing member connected with the blade. The biasing member includes at least one second fixation element that is selectively engageable with the at least one first fixation element to releasably dispose the blade in a selected orientation relative to the first end. Systems and methods of use are disclosed. | 2014-03-06 |
20140066720 | PATIENT-MATCHED INSTRUMENTATION AND METHODS - A patient-matched cutting block including a surface or point contact features adapted to at least partially conform to or reference a patient specific anatomy. The cutting block having guide slots configured for guiding the movement of cutting tools relative to the patient specific anatomy or features configured to mate to and guide standard cutting guides relative to patient specific anatomy in order to form plateau and eminence resections of the patient specific anatomy. | 2014-03-06 |
20140066721 | Apparatus and Method for Ventral Only Ablation of the Tongue - Apparatus and methods for ventral only ablation of the tongue, for use in treating sleep apnea and related breathing disorders. An RF ablation probe or wand is inserted in ventral surface of a patient's tongue in a superior plane along a longitudinal (i.e., anterior to posterior) axis of the tongue, to a predetermined depth. The wand is withdrawn, RF energy is applied, creating a lesion predominantly in the interior of the tongue in an anterior to posterior plane, thereby resulting in less scarring but appreciable movement of the posterior tongue base away from the posterior pharyngeal wall. Also disclosed is a tongue retractor device used for measuring the depth of wand insertion, lifting the tongue to expose the ventral surface of the tongue for the procedure, and providing a stop surface to inhibit further wand insertion. | 2014-03-06 |
20140066722 | Surgical Lamps and Methods for Illuminating Operating Sites - A surgical lamp for illuminating an operating site includes a lamp body that includes first and second light sources that respectively generate first and second light fields of different diameter on the operating site. When a change in a distance between the lamp body and the operating site is detected, the first and second light intensities of the first and second light sources, respectively, can be controlled such that the predetermined diameter (dx) at which the preset relative central illuminance (Ecx) of the resultant light field is generated is maintained at a substantially constant value as the distance changes. | 2014-03-06 |
20140066723 | White coherent laser light launched into nano fibers for surgical illumination - Disclosed is an exemplary surgical illumination system that includes a first laser configured to emit a first light beam having a first spectral range, and an illumination probe optically connectable to the first laser. The first laser may be configured as a supercontinuum laser. The surgical illumination system may include a second laser configured to emit a second light beam having a second spectral range, and a beam combiner for combing the first and second laser beams to form a third laser beam having a spectral range of the first and second lasers. The illumination probe includes a fiber optic cable for delivering at least a portion of the first light beam to a surgical site. The fiber optic cable includes a fiber optic core having a diameter of 100 microns or less. | 2014-03-06 |
20140066724 | System and Methods for Evaluating Vocal Function Using an Impedance-Based Inverse Filtering of Neck Surface Acceleration - A system and method to assess vocal function of a subject. The system includes an accelerometer configured to acquire surface acceleration data associated with vocal functionality of the subject and a computer system configured to analyze the surface acceleration data and to estimate glottal airflow wave-forms produced by the subject based on the surface acceleration data. The computer system performs the analysis and estimation by applying an inverse filter to the surface acceleration data based on a calibrated transmission line model and generates an indication of vocal functionality of the subject based on the estimated glottal airflow waveforms. | 2014-03-06 |
20140066725 | METHOD AND APPARATUS FOR DETECTING INEFFECTIVE INSPIRATORY EFFORTS AND IMPROVING PATIENT-VENTILATOR INTERACTION - A method and system for detecting an ineffective effort of a patient being mechanically ventilated by a ventilator comprises (i) monitoring a respiratory flow of air of the patient after said ventilator has cycled; (ii) creating a signal indicative of said flow; (iii) removing artefact from said signal; (iv) monitoring said signal for perturbations; and (v) determining that an ineffective effort has occurred when said perturbation is significant. | 2014-03-06 |
20140066726 | Biological Sample Collection Device and System - A biological sample collection device includes a top cover plate, a bottom portion attached to the top cover plate, the bottom portion comprising a remotely-analyzable biological sample collection portion to collect a biological sample from a body of a subject. The biological sample is to be analyzed at a remote processing facility at a later time. A fastening portion is provided on the bottom portion to affix the remotely-analyzable biological sample collection device to the body of the subject. A real time clock is coupled to the top cover plate and a memory is coupled to the top cover plate and electrically coupled to the real time clock. The remotely-analyzable biological sample collection device may further include a processing unit, at least two electrodes coupled to the processing unit, and a transbody conductive communication module. Additionally, a remotely-analyzable biological sample collection device communication system includes a wireless communication device configured to communicate with a communication device external to the patient. | 2014-03-06 |
20140066727 | SPACER ATTACHMENT FOR A DERMATOSCOPE - The spacer attachment for a dermatoscope comprises an outer sleeve ( | 2014-03-06 |
20140066728 | System for Measuring Skin Hydration - A system for measuring skin hydration at a measurement site with a independent measurement probe and a portable data processing system. Wireless communications enable the transfer of commands and data between the probe and portable data processing system. The portable data processing system can comprise a wireless tablet or smartphone. The portable data processing system provides input functions and output functions on its display and includes a camera for imaging the measurement site. | 2014-03-06 |
20140066729 | Sampling Device And System For Capturing Biological Targets Of A Body Fluid, And Process For Manufacturing This Device - The invention relates to a sampling device adapted to be inserted into a hollow tubular endpiece of the needle or catheter type, and to emerge from the endpiece with a view to contact with a bodily fluid containing biological samples to be sampled, to a sampling system incorporating this endpiece and this device, which is mounted so as to slide in the latter, and to a method for manufacturing this device. | 2014-03-06 |
20140066730 | SYSTEM FOR IN-VIVO MEASUREMENT OF AN ANALYTE CONCENTRATION - The analyte concentration, such as glucose, in a human or animal body is measured with an implantable sensor that generates measurement signals. The measurement signals are compressed through statistical techniques to produced compressed measurement data that can is easier to process and communicate. A base station carries the implantable sensor along with a signal processor, memory, and a transmitter. A display device is also disclosed that can receive the compressed measurement data from the base station for further processing and display. | 2014-03-06 |
20140066731 | Batteryless Portable Medical Devices - This embodiment relates to portable handheld medical devices and in particular to handheld devices functioning without batteries. The medical devices connect to an external system and receive power. The external system may refer to any of everyday devices like a laptop or a mobile phone and so on. The medical devices operate once the power source i.e. the external device is connected. The medical devices can be shut down after use and connection between the external system and handheld medical devices is removed. | 2014-03-06 |
20140066732 | SYSTEM AND METHOD FOR DETERMINING CARDIAC OUTPUT - A system is configured to determine cardiac output of a patient. The system may include a first sub-system configured to detect a first physiological signal, and a second sub-system configured to detect a second physiological signal that differs from the first physiological signal. The first and second sub-systems may be separate and distinct from one another. The system may also include a cardiac output determination module that is configured to determine the cardiac output based, at least in part, on the first and second physiological signals. | 2014-03-06 |
20140066733 | ENDOSCOPE SYSTEM, PROCESSOR DEVICE THEREOF, AND IMAGE PROCESSING METHOD - In imaging an oxygen saturation level of blood, measurement light having a wavelength of 450 to 500 nm, B light, G light, and an R light are sequentially taken out of broad band light BB emitted from a xenon lamp. An internal body portion is imaged under irradiation with the measurement, B, G, and R light to obtain image data B | 2014-03-06 |
20140066734 | Apparatus and Method for Measuring Biochemical Parameters - In a first embodiment, electrodes are coupled to a surface at first, second, and third locations, the first location being further from the third location than from the second location. Impedance is measured at distinct frequencies between pairs of the electrodes. As a result, impedance is measured at differing regions below the surface, one region being deeper below the surface than the other region. In a second embodiment, a microfluidic device carries out an analysis. The analysis may be within a flexible patch adhered to a surface, or may be in a solid device implanted in a body of liquid surrounded by tissue. The analysis may involve pumping a fluid or may involve drawing an analyte electrophoretically through a microfluidic channel. | 2014-03-06 |
20140066735 | DIABETES MANAGER FOR GLUCOSE TESTING AND CONTINUOUS GLUCOSE MONITORING - A handheld diabetes management device for managing blood glucose test data and continuous glucose monitoring data includes a port configured to receive a test strip, a wireless transceiver, a communications processor, and a user interface processor. The communications processor communicates with the wireless transceiver to periodically collect glucose measurement data from a continuous glucose monitoring device and to store the glucose measurement data in a first data storage module. The communications processor is operable to consume electrical power at a first rate. The user interface processor communicates with the communication processor to receive the glucose measurement data and operable to display the glucose measurement data on the device. The communications processor operates asynchronously from operation of the user interface processor to collect the glucose measurement data and the user interface processor operates to consume electrical power at a second rate that is higher than the first rate. | 2014-03-06 |
20140066736 | Analyte Sensor Calibration Management - Methods, devices, and systems for calibrating an analyte sensor are provided. Embodiments include determining a sensitivity value associated with an analyte sensor, retrieving a prior sensitivity value associated with the analyte sensor, determining whether a variance between the determined sensitivity value and the retrieved prior sensitivity value is within a predetermined sensitivity range, determining a composite sensitivity value based on the determined sensitivity value and the retrieved prior sensitivity value, and assigning a successful calibration sensitivity value based on the retrieved prior sensitivity value when the variance is within the predetermined sensitivity range. | 2014-03-06 |
20140066737 | SENSOR FOR MONITORING A CONDITION OF A PATIENT - A sensor may include a substrate having a sensing portion defining a sensor thereon and a circuit mounting portion defining at least one electrically conductive pad that is electrically connected to the sensor. The sensor may be configured to produce a signal indicative of a condition of the patient. An anisotropic medium may be disposed on the circuit mounting portion and may be electrically conductive in a direction through the medium and electrically insulating in directions along the medium. An electrical circuit may be mechanically mounted to the circuit mounting portion of the first substrate via the anisotropic medium with at least one electrically conductive terminal juxtaposed over the at least one electrically conductive pad. The anisotropic medium may establish local electrical contact between the at least one electrically conductive terminal and the at least one electrically conductive pad. | 2014-03-06 |
20140066738 | SYSTEMS, DEVICES, AND METHODS FOR MAPPING ORGAN PROFILES - Devices, systems, and methods for the localization of body lumen junctions and other intraluminal structure are disclosed. Various embodiments permit clinicians to identify and locate lesions and/or anatomical structures within a lumen and accurately place leads and/or devices within a lumen, through determining the intralumen conductance and/or cross-sectional area at a plurality of locations within the body lumen. | 2014-03-06 |
20140066739 | SYSTEM AND METHOD FOR QUANTIFYING OR IMAGING PAIN USING ELECTROPHYSIOLOGICAL MEASUREMENTS - A method for computing a quantitative metric indicative of pain experienced by a subject using an electrophysiological signal detection system is provided. Electrophysiological data are acquired from a subject with the electrophysiological signal detection system. Modulations in the acquired electrophysiological data that are associated with pain experienced by the subject during the acquisition of the electrophysiological data are identified. A quantitative metric indicative of the pain experienced by the subject is computed by processing the identified modulations in the acquired electrophysiological data. | 2014-03-06 |