09th week of 2014 patent applcation highlights part 40 |
Patent application number | Title | Published |
20140057210 | METHODS OF FABRICATION OF CARTRIDGES FOR BIOLOGICAL ANALYSIS - Methods to fabricate reaction cartridges for biological sample preparation and analysis are disclosed. A cartridge may have a reaction chamber and openings to allow fluids to enter the chamber. The cartridge may also have handles to facilitate its use. Such cartridges may be used for polymerase chain reaction. | 2014-02-27 |
20140057211 | METHOD OF FORMING TIGHT-PITCHED PATTERN - The present invention provides a method of forming tight-pitched patterns. First, a target pattern is provided, wherein the target pattern comprises a plurality of first stripe patterns, and each of the first stripe patterns has a first width and a first length. Then, a photomask comprising a plurality of second stripe patterns corresponding to the first stripe patterns is provided, and each of the second stripe patterns has a second width and a second length. Then, a first exposure process with the photomask is provided in an exposure system, wherein the first exposure process uses a first light source that can resolve the second width of each of the second stripe patterns. Lastly, a second exposure process with the photo-mask is provided in the exposure system, wherein the second exposure process uses a second light source that cannot resolve the second width of each of the second stripe patterns. | 2014-02-27 |
20140057212 | TRANSMISSION APPARATUS, DRAWING APPARATUS, AND METHOD OF MANUFACTURING ARTICLE - The present invention provides a transmission apparatus for transmitting a light signal between an outside and an inside of a vacuum chamber, comprising a plurality of first transmission lines configured to transmit a plurality of light signals outside the vacuum chamber, a plurality of second transmission lines configured to transmit the plurality of light signals inside the vacuum chamber, and a light-transmissive member configured to transmit the light signals between the plurality of first transmission lines and the plurality of second transmission lines, wherein the light-transmissive member has a structure formed to isolate light paths of the plurality of light signals between the plurality of first transmission lines and the plurality of second transmission lines from each other. | 2014-02-27 |
20140057213 | BOIL AND BOIL-DRY DETECTION SYSTEMS FOR COOKING APPLIANCES USING VIBRATION SENSORS - A cooking sensor system that includes a burner assembly; and a vibration sensor assembly configured to generate a vibration signal that corresponds to vibrations of cookware situated on the burner assembly. The cooking sensor system also includes a processor to receive the vibration signal and determine at least one of a boiling condition and a boil-dry condition for a liquid contained within the cookware, wherein the determination is based at least in part on the vibration signal. The cooking sensor system further includes an indicator element coupled to the processor to indicate the at least one of a boiling condition and a boil-dry condition. The cooking sensor system may also include a control element coupled to the processor to operate the burner assembly based at least in part on the at least one of a boiling condition and a boil-dry condition. | 2014-02-27 |
20140057214 | BOIL AND BOIL-DRY DETECTION METHODS FOR COOKING APPLIANCES USING VIBRATION SENSORS - A method of boil and boil-dry detection for appliances. The method includes the steps: detecting vibrations that correspond to cookware situated on a burner assembly; generating a vibration signal based on the vibrations; and performing signal processing on the vibration signal. The method also includes the steps: collecting vibration data related to the vibration signal; and detecting boiling and boil-dry conditions for a liquid contained within the cookware based at least in part on an evaluation of the vibration data. The method may also include the steps: indicating the boiling and boil-dry conditions; and controlling the burner assembly based at least in part on the boiling and boil-dry conditions. | 2014-02-27 |
20140057215 | COMBUSTION FURNACE AND METHOD OF OPERATION - A combustion furnace and a method of its operation are described. The furnace comprises a chamber defining a combustion volume having at least one primary inlet for fuel and combustion supporting gases and at least one primary outlet for combustion product gases, which chamber is provided with one or more additional ports, for example in fluid communication with a supply of gas for secondary gas flow, allowing for secondary gas flow into and/or out of the combustion volume. | 2014-02-27 |
20140057216 | PROCESS FOR ACHIEVING TOTAL COMBUSTION WITH THE HELP OF INJECTORS AND INJECTORS - This invention refers to a process for achieving the total combustion of fuels, which can reduce pollution in the atmosphere, solve (in great part) the climate crisis, stop the greenhouse effect-humanity is facing, and combat global warming. The invention's field of use is very wide, for example in engines of vehicles, in engines for airplane propulsion, in engines for ships, and in other equipment for transportation, combustion, and generation of electricity. This process involves using several types of injectors and compressed air. In this regard, the air can be compressed at a pressure of 5 to ∞ ATM, be passed through a vacuum created in a pipe, and absorb fuel in the mass of the compressed air to achieve total combustion and the number of compressed air molecules necessary to cause the total combustion of one molecule of hydrocarbon, for the various types of hydrocarbons discussed herein. | 2014-02-27 |
20140057217 | Burner - A burner having a secondary air regulator is provided. The secondary air regulator has an end plate having a bored hole penetrating in an axial direction and for forming a cylindrical space with peripheral surface opened in a space with the furnace core side surface of the wind box, a rotary damper having a bored hole penetrating in an axial direction and being capable to open or close the hole on the end plate by rotating in a peripheral direction, a sliding damper for surrounding the cylindrical space and being slidable in an axial direction, air vanes installed at a predetermined distance along circumference of the cylindrical space and for giving swirling to the secondary air, first driving means for rotating the rotary sliding damper, and second driving means for sliding the sliding damper. | 2014-02-27 |
20140057218 | DUAL FUEL HEATER WITH SELECTOR VALVE - A heater assembly can be used with a gas appliance. The gas appliance can be a dual fuel appliance for use with one of a first fuel type or a second fuel type different than the first. The heater assembly can include at least one pressure regulator, a housing, and an actuation member. The housing has a first fuel hook-up for connecting the first fuel type to the heater assembly, and a second fuel hook-up for connecting the second fuel type to the heater assembly. The actuation member can control a flow through the heater assembly based on whether the first or the second fuel hook-up is used. | 2014-02-27 |
20140057219 | Systems and Methods for Heating a Liquid Fuel of a Candle - Systems and methods for heating a candle fuel generally comprise: a vessel to contain a quantity of a liquid fuel, and a wick system configured to float upon the quantity of the liquid fuel and to transfer heat to the liquid fuel, wherein the wick system comprises a wick and a wick holder. The wick comprises a first wick material configured to support a flame from a combustion and a second wick material, proximate to the first wick material, and configured to absorb combustion products from the combustion. The wick holder is configured to support the wick, such that at least a portion of the wick is immersed in the quantity of the liquid fuel. | 2014-02-27 |
20140057220 | LIGHTER ASSEMBLY - A portable, handheld lighter assembly for lighting a lighting end of a rolled tobacco product, such as a cigarette or a cigar, includes an elongated body formed with opposed first and second channels formed on either side of a combustion zone and a stop formed in the elongated body. The combustion zone traverses the stop so as to couple the first channel in gaseous communication with the second channel. The stop restricts movement of a rolled tobacco product into the second channel from the first channel and restricts movement of a rolled tobacco product into the first channel from the second channel. A lighter is coupled to the elongated body and is for applying lighting heat to the combustion zone at the stop for lighting a lighting end of a rolled tobacco product applied against the stop in the combustion zone from the first channel or the second channel. | 2014-02-27 |
20140057221 | SYSTEM FOR THE THERMAL PREPARATION OF RECLAIMED ROAD MATERIAL CONTAINING PAHS OR OIL SLUDGE - A system for the thermal preparation of reclaimed road material containing PAHs, or of oil sludge having a loading station for pre-comminuted reclaimed road material or oil sludge, a rotary kiln in which the reclaimed road material or the oil sludge is burned, while oxidation air is fed in, a dust separator to which the flue gases produced in the rotary kiln are fed, an after-burner to which the flue gases leaving the dust separator are fed, and a filter to which the flue gases arising in the after-burning means are fed. These components are divided into a plurality of modules, each of which includes a weight and dimension such that each may individually be transported using conventional road transport means, in particular low loaders or heavy goods vehicles. | 2014-02-27 |
20140057222 | ORTHODONTIC BITE JUMPING DEVICE - The present invention relates particularly to an orthodontic device attached to orthodontic brace wires connected to teeth of the upper and lower jaw for treatment of Class II malocclusions. The orthodontic bite jumping device is attached to a pair of orthodontic brace wires affixed to a patient's teeth for correcting a relative position of dental arches. The device comprises one tubular member having an eyelet at one end for connection to a first brace wire and a tube stop at another end and one plunger member slidably and concentrically disposed in the tubular member. The plunger member includes an eyelet at one end for connection to a second brace wire and a plunger stop, such that the plunger stop when coupled with the tube stop is adapted to prevent disengagement of the plunger member from the tubular member when mouth of the patient is opened to a maximum position. | 2014-02-27 |
20140057223 | FILM ILLUMINATION SYSTEM - An illuminator film system may include one or more pre-cut sections of optical film applied to a waveguide to allow light to exit the waveguide through the film in a predetermined manner. The one or more pre-cut sections may be removed and reapplied during a procedure to redirect the light. A laminated illuminator film may be provided that uses a laminated optical film structure to direct light from a fiber optic input. Such a laminated illuminator film may be very low profile, low cost and easy to apply to a retractor for providing illumination during a surgical procedure. | 2014-02-27 |
20140057224 | SURGICAL GUIDING DEVICE - A surgical guiding device comprises: an elongate portion comprising a handpiece connection port and a shank connection port, wherein sizes of the handpiece connection port and the shank connection port comply with the ISO1797 standard; a height controlling portion being a hollow cylinder with two end openings, and having a first end portion and a second end portion; and a retaining portion disposed on an outer surface of the height controlling portion to adjust an installation height of the height controlling portion in relation to a surgical positioning device. The present invention comply with the ISO1797 standard and it is not necessary to persistently exchange the different sizes of movable sleeves to simply the implanting process, so as to shorten the time of the surgery and reduce the consumption of the cost. Therefore, the present invention also can reduce the discomfort and pain of the patient in treating process. | 2014-02-27 |
20140057225 | INSERT FOR ULTRASONIC IRRIGATION TO BE ENGAGED IN A DENTAL ULTRASOUND DEVICE - The present Utility Model Patent refers to an innovative constructive layout applied to an ultrasonic insert for irrigation to be engaged in a dental ultrasound device. The present invention is basically comprised of an elongated and slender rod ( | 2014-02-27 |
20140057226 | ENDODONTIC INSTRUMENTS WITH PILOT TIPS AND PARABOLIC CUTTING FLUTES - A series of multi-tapered parabolic implements is disclosed for endodontic use. The instruments comprise different sections: a pilot tip, a first portion adjacent the pilot tip and a second portion adjacent the shank. The two portions have different tapers. The tapers of the two different portions blend into each other along a parabola-shaped surface. The pilot tip is radiussed for ease of entry into a root canal with increased safety. | 2014-02-27 |
20140057227 | SURGICAL TEMPLATE POSITIONING DEVICE - A surgical template positioning device, which comprises a template, a prosthetic tooth and a dental mold. The template has a first surface and a second surface, the first surface is formed with at least three spherical recesses and a guiding hole, relative positions of the spherical recesses define a triangle, and the guiding hole passes through the template. The prosthetic tooth has at least three spherical portions and one implanted hole, the spherical portions are combined with the spherical recesses of the first surface, and the guiding hole is corresponding to the implanted hole. The dental mold fixes the prosthetic tooth to a soft tissue between adjacent teeth. The present invention not only can save the manufacturing time and cost of the surgical template positioning device, but also is convenient to operate and exactly position, so as to increase the success rate of implanting surgery. | 2014-02-27 |
20140057228 | SAFETY SUBANTRAL MEMBRANE LIFT CAPABLE OF DIRECTLY ADJUSTING A SUBANTRAL MEMBRANE TO SAFELY LIFT THE SUBANTRAL MEMBRANE IN A DESIRED DIRECTION BY A DESIRED DISTANCE, AND OPERATING METHOD USING SAME - Disclosed is a safety subantral membrane lifter including a bone-fixing unit including a bone-fixing arm mounted on the top of the bone-fixing unit, a bone-fixing unit body arranged at the lower end of the bone-fixing unit, and a bone-fixing unit support arranged at the lower end of the bone-fixing unit body. The bone-fixing unit include a bone-fixing unit body; a bone-fixing arm arranged at one end of the bone-fixing unit body and which is inclined toward one end thereof; two side blades protruding outwardly from both sides of the bone-fixing unit body and formed in the vertical direction so as to be sharp; and a bone-fixing support arranged at the lower end of the bone-fixing unit. | 2014-02-27 |
20140057229 | SIMULATOR FOR TRAINING A TEAM, IN PARTICULAR FOR TRAINING A HELICOPTER CREW - The invention relates to a simulator ( | 2014-02-27 |
20140057230 | APPARATUS FOR TEACHING COMMUNICATION SKILLS - A visually impaired person may be taught verbal communication skills using specimen display assemblies that present tactile specimens representing words that are to be learned. The specimens are attached to and project from a surface of a specimen display card. The specimen display card may be used in conjunction with a teaching device such as an easel or an electronic device having a touch sensitive surface and a speaker, whereby the electronic device broadcasts a programmed verbal message from the speaker when a force is imparted to the touch sensitive surface. | 2014-02-27 |
20140057231 | BREAK-FIX SIMULATOR - A system, apparatus, method, and computer program product for implementing at least one break-fix simulation are disclosed. A processor implements the at least one break-fix simulation by invoking a virtualization of a product that is configured to provide a service, executing one or more scripts that are configured to break the virtualization of the product so that at least a portion of the service fails, receiving first input via a user interface that is configured to access one or more tools for restoring the at least a portion of the service to working order, and restoring the at least a portion of the service to working order with the one or more tools utilizing the first input. | 2014-02-27 |
20140057232 | APPARATUS, SYSTEM, AND METHOD FOR MODULATING CONSOLIDATION OF MEMORY DURING SLEEP - Devices, systems and methods to modify memory and/or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. Described herein are systems, methods and devices to enhance a user's cognitive function in memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. The machine may record ambient sensory inputs during awake acquisition or reinforcement/relearning and replay all or an extracted form of the ambient sensory stimuli during a specified portion of the user's sleep. A stimulus may be delivered to a user to affect brain activity during sleep to modulate the phase of a user's sleep, quality of sleep, and/or quality or intensity of brain rhythms during a particular phase of sleep. | 2014-02-27 |
20140057233 | Integrated Training System For Articles Of Footwear - An integrated training system for articles of footwear is disclosed. Each article of footwear includes a set of physical characteristics associated with an athletic skill. A customized training program is provided with each article of footwear to provide custom tailored training for improving the particular athletic skill associated with the selected article of footwear. | 2014-02-27 |
20140057234 | DEVICE FOR TRAINING THE APPLICATION OF COMPRESSION MATERIAL - The invention relates to the training and monitoring of a correct application of compression material. A training extremity ( | 2014-02-27 |
20140057235 | SYSTEM, COMPONENTS AND METHODOLOGIES FOR TRAINING AND TESTING ON CARDIAC COMPRESSIONS - Disclosed are methodologies, a system and components thereof and associated computer programs for providing training/testing of one or more users performing treatment of Sudden Cardiac Arrest(SCA) victims. The system provides computer controlled interactive instruction and testing methodologies that enable one or more users to be trained and/or tested using a plurality of mannequins including circuitry and hardware that enable each users compressions to analyzed for rate, depth and recoil to ensure that each user is performing the chest compressions properly. The data collected for determining rate, depth and recoil are collected via mannequin-specific hardware and electronics that utilize a plurality of magnets provided in proximity to a Hall Effect sensor. Data is collected at each mannequin and transmitted to at least one computer processing unit operating to receive, collect, analyze and display the data as well as store data for subsequent use in individualized training and certification of users. | 2014-02-27 |
20140057236 | COMBINED SOFT TISSUE AND BONE SURGICAL SIMULATOR - A surgery simulator includes a physical surrogate surgical interface that represents an interface between a user and a simulated patient in a simulated surgical scenario that involves manipulation of both simulated hard and soft tissue. Sensor(s) sense the user's manipulation of the surrogate surgical interface. A surgical simulation generator generates a real time 3D surgical simulation of the surgical scenario based on the manipulation sensed by the sensor(s). The real time 3D surgical simulation comprises real time simulation state data. The surgical simulation generator renders the real time simulation state data into a real time computer graphics generated video representation of the surgical simulation and provides the real time video representation to a display for real time viewing by the user. The surgical simulation generator simulates effects of the manipulation on both simulated hard tissue and simulated soft tissue of the simulated patient. | 2014-02-27 |
20140057237 | METHOD FOR PARKING A VEHICLE BY USING A PARKING ASSISTANT SYSTEM - A method for parking a vehicle enables a driver to park a vehicle easily and quickly by using a parking assistant system. Based on the distance from the vehicle to an adjacent vehicle detected or calculated by the parking assistant system, and the virtual parking path calculated based on the virtual parking position selected by the target parking frame and the specification of the vehicle, the only thing that the driver needs to do during parking, simply involves turning the steering wheel to the extreme left, right and to the center, and driving the vehicle forward and backward, therefore, the parking operation is very simple and easy. | 2014-02-27 |
20140057238 | System and Method for On-Line Interactive Learning and Feedback - A system and method for on-line interactive learning and feedback is provided. The system elicits user responses and provides a means for the users to evaluate responses and receive feedback from other users and from subject matter experts. | 2014-02-27 |
20140057239 | METHODS AND APPARATUSES FOR FACILITATING ONLINE KNOWLEDGE TRANSFERS - Methods and systems for facilitating online knowledge transfers. The methods and systems may include receiving content, including learning opportunities and learning information from a plurality of sources and transforming the source format of the received content into a common system format when the source format of the content does not match the system format. In addition, the methods and systems include filtering and indexing the content and populating a data repository with the indexed content in the system format. The methods and systems include transmitting a content feed with the content in the system format for generation on an output mechanism. | 2014-02-27 |
20140057240 | COMPUTER-IMPLEMENTED METHOD FOR FACILITATING CREATION OF AN ADVANCED DIGITAL COMMUNICATIONS NETWORK, AND TERMINAL, SYSTEM AND COMPUTER-READABLE MEDIUM FOR THE SAME - A method for facilitating the creation of a digital communications network by collaborative interaction among users at computer interfaces, the method comprising, at a terminal in a digital communications network: receiving question data; collecting answer data, collaboration data, and selection data relating to the terminal; transmitting the collected answer data to at least one first remote terminal; receiving answer data from the at least one first remote terminal responsive to identical question data as the received question data; receiving collaborative data from the first remote terminal; one or more of storing and displaying the question data and responsive answer data; and displaying answer data from the at least one first remote terminal in accordance with whether the at least one first remote terminal is assigned to a same predetermined first-tier group as the terminal in an answer data driven device hierarchy. A terminal, system and computer-readable medium are also disclosed. | 2014-02-27 |
20140057241 | Evaluating Candidate Answers To Questions In A Target Knowledge Domain - Evaluating candidate answers to questions in a target knowledge domain, including: identifying, by a question answering module, a plurality of evidence items in the target knowledge domain; identifying, by the question answering module, a plurality of answers to questions in the target knowledge domain; determining, by the question answering module, associations between each evidence item and one or more of the answers; receiving, by the question answering module, a question; receiving, by the question answering module, values for the one or more evidence items; and providing, by the question answering module, an answer to the question in dependence upon the associations between each evidence item and one or more of the answers and the values for the one or more evidence items. | 2014-02-27 |
20140057242 | Personalized Electronic Education - In general, in an aspect, embodiments of the invention can provide, a semi- or fully-automatic computer-implemented method for personalized electronic education of a student, the method including, performing a computerized assessment of the student, using a knowledge assessment module, to determine a knowledge deficit of the student associated with at least one concept, defining a learning profile for the student using a learning profile generation module, receiving, at a server module, a computerized explanation submission based on the learning profile, evaluating, using an explanation submission evaluation module of the server module, the received explanation submission based on an understanding of the concept by the student after presentation to the student of the explanation submission, and rating, using the explanation submission evaluation module, the explanation submission based on the evaluation. | 2014-02-27 |
20140057243 | EDUCATIONAL SYSTEM, TEACHER INFORMATION TERMINAL, STUDENT INFORMATION TERMINAL, INTEGRATED CIRCUIT, AND CONTENT DISPLAY METHOD - A teacher information terminal includes a communication unit which transmits paging-forward instructions for instructing turning-forward of a page of the content, concurrently to student information terminals each time a page of the content is turned forward, and each of the student information terminals includes: a communication unit which receives a paging-forward instruction from the teacher information terminal; an inquiry unit which makes an inquiry to a user about whether or not the user accepts the paging-forward instruction when the communication unit receives the paging-forward instruction; and a paging-forward processing unit which turns forward the page of the content when a result of the inquiry is that the user accepts the paging-forward instruction, and avoids turning forward the page of the content when the result of the inquiry is that the user does not accept the paging-forward instruction. | 2014-02-27 |
20140057244 | Predictive Executive Functioning Models Using Interactive Tangible-Graphical Interface Devices - A method of diagnosing attention deficit hyperactivity disorder (ADHD). The method employs a tangible graphical interactive game wherein the interactive game employs a plurality of tangible graphical cubes. The game induces stimuli, measures responses and accumulates the responses using a predefined set of variables into a predefined set of metrics, wherein the variables are determined using an interactive machine learning feedback algorithm. | 2014-02-27 |
20140057245 | Machine That Simulates The Movement Produced During Transport - The invention relates to a machine that simulates movement during transport, for the testing of packaging elements. The machine comprises: a load platform ( | 2014-02-27 |
20140057246 | DEMONSTRATION CASE WITH ECCENTRIC TILT DISPLAY PANEL - A demonstration case having an eccentric tilt panel display assembly is provided for safely securing, transporting, and demonstrating industrial products or equipment. The demonstration case may reduce damage to display products that may occur from dropping the demonstration case or from joggling of display products during transport. The demonstration case may also help stably maintain the display product in a display or demonstration mode. | 2014-02-27 |
20140057247 | METHOD OF PREPARING RNA FROM RIBONUCLEASE-RICH SOURCES - Methods for preparing RNA from ribonuclease-rich sources while avoiding RNA degradation are described. The lysis protocol for ribonuclease-containing samples is performed at high pH to accelerate cell lysis and with a reducing agent that inactivates ribonucleases (RNases) by reducing disulfide bonds essential for RNase activity. Samples are briefly incubated for up to five minutes at high pH followed by addition of a reagent to lower the pH to a level at which the RNA is stable. This method of RNA extraction has many advantages over existing methods of RNA preparation, including that cell lysis is efficient, RNases are rapidly inactivated, and sample incubation times are short (less than 5 minutes), which protects RNA from degradation. The lysing procedure is performed entirely in aqueous solution with no heating, precipitations, or buffer exchanges required. Thus, a quick, simple procedure for extracting RNA is provided, which can easily be automated. | 2014-02-27 |
20140057248 | FLUORESCENCE ENERGY TRANSFER BY COMPETITIVE HYBRIDIZATION - A method is provided for detecting the presence of nucleotides or monitoring nucleotide amplification. It utilizes fluorescence energy transfer by competitive hybridization. Competitive hybridization is achieved by using unequal length complementary probes which have a fluorophore on one probe and a quencher on the other. The fluorophore and quencher are juxtaposed in a manner wherein the proximity of the quencher to the fluorophore produces quenching of the fluorescence of the fluorophore. | 2014-02-27 |
20140057249 | JAK/STAT INHIBITORS AND MAPK/ERK INHIBITORS FOR RSV INFECTION - The present invention concerns a method for treating or reducing the likelihood of developing a respiratory syncytial virus (RSV) infection in a subject by administering an effective amount of an inhibitor of the janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway or the mitogen-activated kinase (MAPK)/extracellular signal-regulated kinase (ERK1/2) signaling pathway to the subject. Another aspect of the invention concerns a pharmaceutical composition that includes an inhibitor of JAK/STAT or MAPK/ERK signaling to the subject; and a pharmaceutically acceptable carrier. Another aspect of the invention concerns a method for identifying agents useful for treating or reducing the likelihood of developing an RSV infection | 2014-02-27 |
20140057250 | Compositions Comprising Human Embryonic Stem Cells and Their Derivatives, Methods of Use, and Methods of Preparation - The present invention relates to a pharmaceutical composition comprising of preparations of human embryonic stem (hES) cells and their derivatives and methods for their transplantation into the human body, wherein transplantation results in the clinical reversal of symptoms, cure, stabilization or arrest of degeneration of a wide variety of presently incurable and terminal medical conditions, diseases and disorders. The invention further relates to novel processes of preparing novel stem cell lines which are free of animal products, feeder cells, growth factors, leukaemia inhibitory factor, supplementary mineral combinations, amino acid supplements, vitamin supplements, fibroblast growth factor, membrane associated steel factor, soluble steel factor and conditioned media. This invention further relates to the isolation, culture, maintenance, expansion, differentiation, storage, and preservation of such stem cells. | 2014-02-27 |
20140057251 | Cannabis Genomes and Uses Thereof - Using the efficiency of next generation sequencing, a draft de novo reference sequence for the | 2014-02-27 |
20140057252 | Binary DNA Probe for Fluorescent Analysis of Nucleic Acids - The invention is directed to binary oligonucleotide probes for nucleic analysis, which probes can be made of DNA or RNA that recognize nucleic acid analytes (both DNA and RNA) with unprecedented high selectivity under mild conditions and are highly sensitive to single nucleotide mismatches (SNP single nucleotide polymorphisms) without PCR amplification. In one group, the binary probes indicate that they have hybridized to a particular nucleic analyte by binding to a molecular beacon that gives off a fluorescent signal. A second group of binary probes bind to a dye such as malachite green, where upon hybridization to analyte the fluorescence of the dye increases dramatically and is easily detected and measured. The new binary probes require only about five minutes at room temperature to generate a detectable signal. | 2014-02-27 |
20140057253 | METHOD TO PREDICT THE PATTERN OF LOCOMOTION IN HORSES - The present invention provides methods for predicting the pattern of locomotion in a horse including the ability of a horse to use different gaits and the ability to trot at a fast speed. The methods comprise determining in a sample of DNA obtained from a horse the presence or absence of at least one genetic marker, wherein said at least one genetic marker is located on horse chromosome 23, said marker being associated with the ability to use different gaits. The invention further provides primers that amplify markers being associated with the ability to use different gaits and hybridization probes to detect markers being associated with the ability to use different gaits and the ability to trot at a fast speed. | 2014-02-27 |
20140057254 | METHODS AND REAGENTS FOR REDUCING NON-SPECIFIC AMPLIFICATION - The present invention provides methods and reagents for use in the amplification of nucleic acids. Amplification carried out using oligonucleotides containing modified nucleotides can result in less non-specific amplification compared to amplification carried out using unmodified oligonucleotides. | 2014-02-27 |
20140057255 | Systems and Methods for Collecting and Transmitting Assay Results - Systems and methods are provided for collecting, preparing, and/or analyzing a biological sample. A sample collection site may be utilized with one or more sample processing device. The sample processing device may be configured to accept a sample from a subject. The sample processing device may perform one or more sample preparation step and/or chemical reaction involving the sample. Data related to the sample may be sent from the device to a laboratory. The laboratory may be a certified laboratory that may generate a report that is transmitted to a health care professional. The health care professional may rely on the report for diagnosing, treating, and/or preventing a disease in the subject. | 2014-02-27 |
20140057256 | HAIRPIN-TYPE PROBE FOR DETECTING TARGET MATERIAL AND METHOD FOR DETECTING TARGET MATERIAL USING THE SAME - The present invention relates to a hairpin-type probe for detecting a target substance and a method for detecting a target substance using the probe. The hairpin-type probe comprises a loop comprising a target substance recognition site, and a stem comprising an aptamer having an electrochemical signaling material bound thereto. The hairpin structure is broken when it is hybridized to the target substance, and thus the signaling material is separated from the aptamer and can freely move to the electrode. Based on the change in the electrochemical signal generated from the signaling material, the amount of the target substance can be accurately detected in real-time. | 2014-02-27 |
20140057257 | IN VITRO METHOD FOR THE PROGNOSIS OF PROGRESSION OF A CANCER AND OF THE OUTCOME IN A PATIENT AND MEANS FOR PERFORMING SAID METHOD - The present invention relates to the prognosis of the outcome of a cancer in a patient, which prognosis is based on the quantification of one or several biological markers that are indicative of the presence of, or alternatively the level of, the adaptive immune response of said patient against said cancer. | 2014-02-27 |
20140057258 | METHOD OF DIAGNOSING MILD OSTEOARTHRITIS - The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in individuals with mild osteoarthritis as compared with individuals without osteoarthritis. Polynucleotides and proteins which specifically and/or selectively hybridize to the products of the biomarkers of the invention are also encompassed within the scope of the invention as are kits containing said polynucleotides and proteins for use in diagnosing mild osteoarthritis. Further encompassed by the invention is the use of the polynucleotides and proteins which specifically and/or selectively hybridize to the product of the biomarkers of the invention to monitor disease regression in an individual and to monitor the efficacy of therapeutic regimens. The invention also provides for methods of using the products of the biomarkers of the invention in the identification of novel therapeutic targets for osteoarthritis. | 2014-02-27 |
20140057259 | METHODS FOR ANALYSIS OF NUCLEIC ACID MOLECULES DURING AMPLIFICATION REACTIONS - The present invention provides systems, methods and kits for performing a detection assay (e.g., invasive cleavage assay) in combination with an amplification assay (e.g., PCR), where the detection assay employs enzyme footprint probes with relatively short (e.g., 6-12 bases) analyte-specific regions configured to provide a preferred footprint length of duplex for use with a particular nucleic acid modifying enzyme. In some embodiments, such assays are used for target quantification, and in other embodiments, such assays are used for genotyping. In certain embodiments, the use of such short probes allows for assays with increased dynamic range. | 2014-02-27 |
20140057260 | MATERIALS AND METHOD FOR ASSAYING FOR METHYLATION OF CpG ISLANDS ASSOCIATED WITH GENES IN THE EVALUATION OF CANCER - Provided are methods, reagents, and kits for evaluating cancer, such as prostate cancer, in a subject. Disclosed methods of evaluating cancer include methods of diagnosing cancer, methods of prognosticating cancer and methods of assessing the efficacy of cancer treatment. The methods include assaying a biological sample for methylation of a CpG island associated with specified genes. Provided reagents and kits include primers suitable for amplifying at least a portion of a target CpG islands associated with specified genes. | 2014-02-27 |
20140057261 | METHODS OF DIAGNOSING, CLASSIFYING AND TREATING ENDOMETRIAL CANCER AND PRECANCER - Diagnostic and therapeutic applications for endometrial cancer are described. The diagnostic and therapeutic applications are based on certain activation mutations in the FGFR2 gene and its expression products. The present invention is directed to nucleotide sequences, amino acid sequences, probes, and primers related to FGFR2 activation mutants and kits comprising these mutants to diagnosis and classify endometrial cancer in a subject. | 2014-02-27 |
20140057262 | METHODS AND MATERIALS FOR USING THE CONTENTS OF PHAGOCYTES TO DETECT NEOPLASMS - This document provides methods and materials related to detecting premalignant or malignant neoplasms (e.g., colorectal and pancreatic cancer). For example, methods and materials for assessing the contents of phagocytes for the presence of one or more biological markers (e.g., Alu repeats or methylated nucleic acid) of premalignant or malignant neoplasms are provided. | 2014-02-27 |
20140057263 | MODIFIED HYBRIDIZATION PROBES - The invention relates to a method for detecting a nucleic acid of an organism in a composition, comprising the steps of, (i) amplifying the nucleic acid to be detected, (ii) during or after amplification, hybridizing to said nucleic acid to be detected a first probe that comprises an abasic site additionally optionally carrying a detectable label, (iii) wherein the position of the abasic site corresponds to a position in said nucleic acid to be detected, known to have a polymorphism in said organism, and wherein said nucleic acid is detected if hybridization occurs. | 2014-02-27 |
20140057264 | DETECTION OF TARGET NUCLEIC ACID SEQUENCE BY PTO CLEAVAGE AND EXTENSION-DEPENDENT CLEAVAGE - The present invention relates to the detection of a target nucleic acid sequence by a PCEC (PTO Cleavage and Extension-Dependent Cleavage) assay. The present invention is characterized by generating a cleavage site for a nucleolytic enzyme on the extended duplex of which the formation is dependent on the presence of a target nucleic acid sequence. The present investion detects the occurrence of the cleavage of the extended duplex, thereby determining the presence of the target nucleic acid sequence. | 2014-02-27 |
20140057265 | Composition and method for determination of ck19 expression - Disclosed is a method for quantitative determination of CK-19 mRNA positive cells in a biological sample. The method can be used, for instance, with peripheral blood to detect cancer in a patient. In one embodiment, the method can be used to detect the cancer before initiation of adjuvant treatment, thereby providing information about therapeutic efficacy. Practice of the invention method is sensitive, reliable, and easy to perform. | 2014-02-27 |
20140057266 | METHODS AND MATERIALS FOR DETECTING GENETIC OR EPIGENETIC ELEMENTS - This document provides methods and materials for detecting genetic and/or epigenetic elements. For example, methods and materials for detecting the presence or absence of target nucleic acid containing a genetic or epigenetic element, methods and materials for detecting the amount of target nucleic acid containing a genetic or epigenetic element within a sample, kits for detecting the presence or absence of target nucleic acid containing a genetic or epigenetic element, kits for detecting the amount of target nucleic acid containing a genetic or epigenetic element present within a sample, and methods for making such kits are provided. | 2014-02-27 |
20140057267 | COMPOSITION AND KIT FOR THE DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT, WHICH MEASURE AN EXPRESSION LEVEL OF LIPOCALIN-2, AND METHOD FOR PROVIDING INFORMATION FOR THE DIAGNOSIS OF MILD COGNITIVE IMPAIRMENT - The present invention relates to a composition for the diagnosis of mild cognitive impairment, which includes a formulation measuring an mRNA or protein expression level of lipocalin-2 gene, to a kit for the diagnosis of mild cognitive impairment, and to a method for providing information for the diagnosis of mild cognitive impairment using the same. According to the present invention, by using the agent for measuring an mRNA or protein expression level of the lipocalin-2 gene, a patient having mild cognitive impairment can be specifically identified by measuring an expression level of lipocalin-2, which is higher in a group of patients having mild cognitive impairment than in both a normal group and a group of patients having Alzheimer's disease.; In particular, it is possible to distinguish between a group of patients having mild cognitive impairment and a group of patients having Alzheimer's disease | 2014-02-27 |
20140057268 | Detection of an Amplification Reaction Product Using pH-sensitive Dyes - Methods are provided for a rapid, low cost approach to monitoring an amplification reaction. This includes monitoring the progress of isothermal or PCR amplification reactions to completion using pH-sensitive dyes that are either colored or fluorescent. Compositions are described that include a mixture of a DNA polymerase, deoxyribonucleotide triphosphate and a weak buffer of less than 1 mM Tris or equivalent or no buffer. | 2014-02-27 |
20140057269 | Materials and Methods for Detection of Nucleic Acids - Assays using non-natural bases are described. In one embodiment, the method involves contacting a sample suspected of containing the target nucleic acid with a polymerase and first and second primers; amplifying the target nucleic acid by PCR using the first and second primers to generate an amplification product having a double-stranded region and a single-stranded region that comprises the non-natural base; contacting the sample with a reporter comprising a label and a non-natural base that is complementary to the non-natural base of the single-stranded region; annealing at least a portion of the reporter to the single-stranded region of the amplification product; and correlating a signal of the label with the presence of the target nucleic acid in the sample. The invention also provides corresponding kits for use in detecting target nucleic acids in a sample. | 2014-02-27 |
20140057270 | COMPOSITIONS AND METHODS FOR DETECTING MUTATIONS IN JAK2 NUCLEIC ACID - The invention disclosed herein is based on the identification of novel mutations in the JAK2 gene and JAK2 protein. The invention provides compositions and methods useful for diagnosing hematopoietic diseases including, for example, myeloproliferalive diseases. The invention also provides compositions and methods useful for determining a prognosis of an individual diagnosed as having a hematopoietic disease. | 2014-02-27 |
20140057271 | DEVICE WITH CONTROLLED FLUID DYNAMICS, FOR ISOLATION OF AN ANALYTE FROM A SAMPLE - Devices for use in extracting an analyte of interest from a sample are described. In one embodiment, a device is comprised of a first plurality of chambers, where one or more chambers in the plurality of chambers has a deep end and a shallow end with a depth d | 2014-02-27 |
20140057272 | METHOD FOR IMMUNE CELL-ASSISTED BACTERIAL CULTURING - A method of culturing fastidious bacteria where a conditioned cell culture medium is prepared in which eukaryotic cells have been cultured, but where the medium is substantially free of the cultured cells. Fastidious bacteria are cultured in the medium. The conditioned cell culture medium can contain secreted factors from the cells. These factors promote the growth of the fastidious bacteria. The fastidious bacterial culture is maintained for a time period sufficient for the fastidious bacteria to multiply. The fastidious bacteria are analyzed using PCR, DNA sequencing or microbiology characterization. | 2014-02-27 |
20140057273 | DIGITAL ASSAYS WITH A REPORTER FOR AMPLICON LENGTH - Digital assay system, includes methods, apparatus, and compositions, for distinguishing and measuring different types of templates according to the different lengths of corresponding amplicons, which may be amplified by the same pair of primers. The system may include a length-sensitive reporter generating luminescence that varies according to amplicon length. The system may, for example, be utilized to identify, distinguish, and/or quantify wild-type and mutant/variant templates, processed and unprocessed template, a target template and a primer dimer, or the like. | 2014-02-27 |
20140057274 | METHODS FOR SEQUENCING POLYNUCLEOTIDES - The invention relates to methods and systems for sequencing and constructing a high resolution physical map of a polynucleotide. In accordance with the invention, nucleotide sequences are determined at the ends of restriction fragments produced by a plurality of digestions with a plurality of combinations of restriction endonucleases so that a pair of nucleotide sequences is obtained for each restriction fragment. A physical map of the polynucleotide is constructed by ordering the pairs of sequences by matching the identical sequences among the pairs. | 2014-02-27 |
20140057275 | DETECTING MULTINUCLEOTIDE REPEATS - Methods of determining the length of a multinucleotide repeat region in a target nucleic acid are provided herein which include labeling amplified target nucleic acids with a target detection label independent of the number of multinucleotide repeats and a repeat-detection label proportional to the number of multinucleotide repeats, wherein the two types of labels are each independently incorporated in the amplified target nucleic acids during the amplifying or after the amplifying; binding the amplified target nucleic acids to a capture probe specific for the amplified target nucleic acids; detecting the target detection label associated with the capture probe to produce a first signal; detecting the repeat-detection label associated with the capture probe to produce a second signal; and determining a ratio of the first signal and the second signal, wherein the ratio is indicative of the length of the multinucletotide repeat region in the target nucleic acid. | 2014-02-27 |
20140057276 | DNA TAGGED MICROPARTICLES - A simulant that includes a carrier and DNA encapsulated in the carrier. Also a method of making a simulant including the steps of providing a carrier and encapsulating DNA in the carrier to produce the simulant. | 2014-02-27 |
20140057277 | DEVICES AND METHODS FOR BIOLOGICAL SAMPLE PREPARATION - Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers. | 2014-02-27 |
20140057278 | PEN-SHAPED DEVICE FOR BIOLOGICAL SAMPLE PREPARATION AND ANALYSIS - Methods and devices for biological sample preparation and analysis are disclosed. A device may have a circular arrangement of containers, with a connecting structure such as a disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. The device may be pen-shaped and have a sample drawing needle connected to the containers. | 2014-02-27 |
20140057279 | DEVICES AND METHODS FOR BIOLOGICAL SAMPLE-TO-ANSWER AND ANALYSIS - Methods and devices for biological sample preparation and analysis are disclosed. A device may have a linear or circular arrangement of containers, with a connecting structure such as a bar or disk. Fluidics channels between containers allow the performance of different techniques for sample preparation, such as lysing, washing and elution. Different functional elements, such as grinders or mixers, may be attached to the containers. The device may have a reaction cartridge with a reaction chamber to perform techniques such as polymerase chain reaction. | 2014-02-27 |
20140057280 | METHODS AND COMPOSITIONS FOR HIGHLY SPECIFIC CAPTURE AND RELEASE OF BIOLOGICAL MATERIALS - Disclosed herein are hydrogel compositions and methods of making hydrogel compositions. Furthermore, methods of specifically capturing and releasing biological materials from a sample using the disclosed hydrogel compositions are disclosed, including methods of utilizing the compositions in microfluidic devices. | 2014-02-27 |
20140057281 | METHOD OF PRODUCING RETINAL PIGMENT EPITHELIAL CELL SHEET - The present invention provides a method of producing a cell sheet including the following steps
| 2014-02-27 |
20140057282 | SWITCHABLE AFFINITY BINDERS - Methods and kits for binding and releasing biological targets, comprising, a binder having an environmentally reactive molecular switch that can switch between a high affinity state, to bind the target, to a low affinity state, to release the target. In one embodiment, the binder is a pre-existing chemical sequence, composition, or structural configuration but unknown or unspecified and still viable as a binder for attaching a molecular switch. | 2014-02-27 |
20140057283 | IMPEDANCE BASED DEVICES AND METHODS FOR USE IN ASSAYS - A method for assaying target molecules in a sample liquid, the method comprising: providing an impedance monitoring device operably connected to an impedance analyzer; adding a sample liquid suspected of having target molecules to the well thereby permitting binding of target molecules to the capture molecules; monitoring impedance of the well; and determining the presence, amount or concentration of target molecules in the liquid sample from the monitored impedance. The device includes a nonconducting substrate having a well, at least two electrodes fabricated on a bottom of the well and on a same plane, wherein the surfaces of the at least two electrodes are modified with capture molecules configured to bind target molecules in a liquid sample, and at least two connection pads electrically connected to the at least two electrodes. | 2014-02-27 |
20140057284 | PHOTOLUMINESCENT MOLECULAR COMPLEX AND METHOD FOR DETERMINING OF THE CONCENTRATION OF SAID MOLECULAR COMPLEX - The invention concerns novel molecular complexes with photoluminescent probes whose specific association with purine-binding proteins leads to increased emission of long lifetime luminescence, and the application of the probes for monitoring activity of protein kinases (PKs) and other purine-binding proteins, screening of compounds as inhibitors of PKs and characterization of inhibitors targeted to the kinase, and methods of manufacturing of such probes. The invention concerns also the use of the improved method for monitoring activity of protein kinases in living cells, characterization of inhibitors of protein kinases, analysis of protein kinase-based disease biomarkers and other tasks of biological and medical importance. | 2014-02-27 |
20140057285 | COMPOSITIONS AND METHODS TARGETING FORCE GENERATION IN KINESIN - In some aspects, the invention provides chimeric kinesin proteins. In other aspects the invention provides nucleic acids encoding chimeric kinesin proteins. Compositions and kits are provided that comprise chimeric kinesin proteins and nucleic acids encoding the same. Antibodies and antigen binding fragments that selectively bind kinesin proteins are also provided. | 2014-02-27 |
20140057286 | Method for Measuring Glycoprotein, Method for Examining Liver Desease, Reagent for Quantitative Determination of Glycoprotein and Glycan-Marker Glycoprotein as an Index for Clinical Conditions of Liver Disease - An object of the present invention is to provide a method for measuring a glycan-marker glycoprotein, by which liver disease can be detected with higher accuracy than is possible with conventional methods. Also, an object of the present invention is to provide a method for examining liver disease, by which liver disease can be detected with higher accuracy than is possible with conventional methods. Also, an object of the present invention is to provide a reagent for quantitative determination of a glycoprotein, which is used for the above measurement methods. Furthermore, an object of the present invention is to provide a glycan-marker glycoprotein as an index for clinical conditions of liver disease, which is capable of identifying the clinical conditions of liver disease depending on the progress of liver disease. The method for measuring a glycoprotein is characterized in that: the glycoprotein is at least one glycoprotein selected from alpha-1-acid glycoprotein (AGP) and Mac-2-binding protein (M2BP) contained in a sample collected from a subject; when the glycoprotein is AGP, AGP binding to a first lectin selected from AOL and MAL is measured; and when the glycoprotein is M2BP, M2BP binding to a second lectin selected from WFA, BPL, AAL, RCA120, and TJAII is measured. | 2014-02-27 |
20140057287 | NOVEL CARDIOMYOCYTE MARKER - The present invention provides a method for production or detection of a cardiomyocyte(s) and/or cardiac progenitor cell(s), comprises extracting a cardiomyocyte(s) and/or cardiac progenitor cell(s) from a cell population comprising cardiomyocytes and/or cardiac progenitor cells using as an index VCAM1 positivity. | 2014-02-27 |
20140057288 | NOVEL ANTI-NOTCH3 ANTIBODIES AND THEIR USE IN THE DETECTION AND DIAGNOSIS OF DISEASE - The present invention relates to novel antibodies that bind specifically to human Notch 3 and their use in the detection and/or diagnosis of Notch 3 related diseases, such as cancer. The present invention also includes nucleic acids encoding these novel antibodies, vectors and cell lines harboring the nucleic acids, and kits comprising the antibodies for use in the detection and diagnosis. | 2014-02-27 |
20140057289 | Micro-Fluidic System Using Micro-Apertures for High Throughput Detection of Cells - A microfluidic detection system for micrometer-sized entities, such as biological cells, includes a detector component incorporating a plate with a plurality of opening, the plate separating two chambers, one in communication with a fluid source containing target entities bound to magnetic beads. The openings are sized to always permit passage of the magnetic beads therethrough into a lower one of the chambers and are further sized to always prevent passage of the target entities from the upper one of the chambers. The detector component further includes a magnet positioned to pull unbound magnetic beads through the openings and to capture target entities bound to magnetic beads on the surface of the plate. In a further feature, the microfluidic detection system is configured to pass target molecules through the plate to be bound to a functionalized surface of the lower chamber. | 2014-02-27 |
20140057290 | METHOD FOR PERFORMING A BIOCHEMICAL ANALYSIS, ESPECIALLY IN OUTER SPACE - The invention is based on a method for performing a biochemical analysis, especially in outer space, wherein at least one analyte in a sample is determined qualitatively and/or quantitatively by means of selective binding of an analyte-specific pair composed of a binding substance and a detection substance to the analyte and by labeling by a labeling substance, and wherein the sample, the binding substance, the detection substance and the labeling substance are mixed in a reaction vessel in one method step. It is proposed that the mixing be brought about by means of mixing bodies. | 2014-02-27 |
20140057291 | BISUBSTRATE FLUORESCENT PROBES FOR PROTEIN KINASE CK2 - This invention relates to fluorescent probes for screening and characterization of compounds binding to protein kinase CK2, measurement of concentration of the catalytically active form of CK2 and imaging of CK2 activity in cells and tissues. The CK2-selective probe of the present invention interacts with binding sites of both substrates of the catalytic subunit of CK2 and therefore can be used for characterization of all inhibitors binding to the active site of CK2 in the binding/displacement assay. The high affinity of the probe affords the detection of the enzyme at low concentration and characterization of inhibitors in a wide affinity range. The invention also relates to the application of the probes for mapping and monitoring of CK2 activity in cells, tissues and live organisms. | 2014-02-27 |
20140057292 | Immunochromatographic Device - The present invention is directed to provide a highly quantitative immunochromatographic device. | 2014-02-27 |
20140057293 | CONJUGATES OF 1,4,7-TRIAZACYCLONONANES, DINUCLEAR METAL COMPLEXES OF SUCH CONJUGATES, AND METHODS OF USE FOR BOTH 1,4,7-TRIAZACYCLONONANES AND CONJUGATES - Conjugates of 1,3-bis(1,4,7-triazacyclonon-1-yl)-2-hydroxypropanes with a variety of conjugating members are used in the formation of dinuclear metal complexes which bind to phosphate esters. By virtue of their conjugated forms, the complexes are incorporated into chromatographic media, affinity binding reagents, and dyes, which make the complexes useful in a wide range of assays, separations, and purifications. In addition, dinuclear metal complexes of 1,3-bis(1,4,7-triazacyclonon-1-yl)-2-hydroxypropanes that are not so conjugated are used in the detection of phosphate esters of biological species by either MALDI-TOF mass spectrometry or by dye displacement. | 2014-02-27 |
20140057294 | A HYBRIDOMA CELL LINE 10G4 AND A MONOCLONAL ANTIBODY AGAINST THE TOTAL OF AFLATOXIN B1, B2, G1 AND G2 - Hybridoma cell line 10G4 and monoclonal antibody against total aflatoxins produced by the hybridoma cell line 10G4. The hybridoma cell line 10G4 is used to produce the monoclonal antibody that binds specifically total aflatoxin B1, B2, G1 and G2. The titer of the mouse ascites antibody produced by the 10G4 treated mouse is determined through non-competitive enzyme-linked immunosorbent assay and the titer can reach up to 5.12×10 | 2014-02-27 |
20140057295 | ANTI-MULLERIAN HORMONE CHANGES IN PREGNANCY AND PREDICTION OF ADVERSE PREGNANCY OUTCOMES AND GENDER - The present invention provides for methods for evaluating the risk of an adverse pregnancy outcome in a subject and methods for treating subjects evaluated as being high risk. In some aspects, the present invention provides a method of evaluating the risk of an adverse pregnancy outcome in a subject, where if the subject does have an abnormal level of AMH as compared to a predetermined normal level the subject is more likely to have an adverse pregnancy outcome, and if the subject does not have an abnormal level of AMH the subject is less likely to have an adverse pregnancy outcome. In other aspects, the present invention provides a method of determining the gender of a fetus comprising obtaining information regarding the level of AMH in a sample from a pregnant subject. | 2014-02-27 |
20140057296 | ASSAYS FOR ANTIBODIES WHICH BIND TO THERAPEUTIC AGENTS - Methods and kits for determining the presence in a patient biological sample of an antibody which binds to an agent (e.g., an enzyme administered in the course of ERT), and optionally determining the neutralizing effect or lack thereof of the antibody on the agent are disclosed. | 2014-02-27 |
20140057297 | Antibodies to Paliperidone Haptens and Use Thereof - Disclosed is an antibody which binds to paliperidone, which can be used to detect paliperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of paliperidone, including multiplex detection of aripiprazole, olanzapine, quetiapine, risperidone and paliperidone in a single lateral flow assay device. | 2014-02-27 |
20140057298 | Antibodies to Paliperidone and Use Thereof - Disclosed is an antibody which binds to paliperidone, which can be used to detect paliperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of paliperidone, including multiplex detection of aripiprazole, quetiapine, olanzapine, and risperidone/paliperidone in a single lateral flow assay device. | 2014-02-27 |
20140057299 | Antibodies to Aripiprazole Haptens and Use Thereof - Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device. | 2014-02-27 |
20140057300 | Antibodies to Aripiprazole and Use Thereof - Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device. | 2014-02-27 |
20140057301 | Antibodies to Risperidone Haptens and Use Thereof - Disclosed is an antibody which binds to risperidone, which can be used to detect risperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of risperidone, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device. | 2014-02-27 |
20140057302 | Antibodies to Risperidone and Use Thereof - Disclosed is an antibody which binds to risperidone, which can be used to detect risperidone in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of risperidone, including multiplex detection of aripiprazole, quetiapine, olanzapine, and risperidone in a single lateral flow assay device. | 2014-02-27 |
20140057303 | Antibodies to Olanzapine Haptens and Use Thereof - Disclosed is an antibody which binds to olanzapine, which can be used to detect olanzapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of olanzapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device. | 2014-02-27 |
20140057304 | Antibodies to Olanzapine and Use Thereof - Disclosed is an antibody which binds to olanzapine, which can be used to detect olanzapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of olanzapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device. | 2014-02-27 |
20140057305 | Antibodies to Quetiapine Haptens and Use Thereof - Disclosed is an antibody which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of quetiapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device. | 2014-02-27 |
20140057306 | Antibodies to Quetiapine and Use Thereof - Disclosed is an antibody which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of quetiapine, including multiplex detection of aripiprazole, quetiapine, olanzapine, and risperidone in a single lateral flow assay device. | 2014-02-27 |
20140057307 | METHOD FOR THE DIAGNOSIS OF DRY EYE AND BLEPHARITIS - The invention relates to a method for the diagnosis of dry eye or blepharitis in a subject which is based on the detection of one or more proteins in a sample from said subject. The invention also relates to a method for differentiating dry eyes and blepharitis. | 2014-02-27 |
20140057308 | METHOD FOR DETECTING PROTEIN S ABNORMALITES - A method of detecting protein S abnormalities of the invention includes the steps of: measuring an activity value of total protein S and a protein content of total protein S in a specimen, and comparing between the protein activity of the total protein S and the protein content of total protein S, which are obtained from the measurements. | 2014-02-27 |
20140057309 | METHOD FOR DETERMINING ENDOGENOUS AND EXOGENOUS MARKERS IN BLOOD - The method of the invention comprises preparing for analysis of a solution which contains substances, blood plasma, plus those substances which were present in whole blood within an adsorbed layer on blood cell surface. The method of the invention characterized in that substances which facilitate the transfer of the substances adsorbed on blood cell surface into the plasma are added to the whole blood sample. A sodium chloride hypertonic solution or a certain amount of a dry salt powder of sodium chloride is added. | 2014-02-27 |