08th week of 2010 patent applcation highlights part 58 |
Patent application number | Title | Published |
20100048822 | POLYPROPYLENE RESIN COMPOSITION - There are provided a polypropylene resin composition and a molded article thereof, the composition comprising:
| 2010-02-25 |
20100048823 | Process for cross-linking thermoplastic polyolefin elastomer compositions - A process for cross-linking an elastomer-containing thermoplastic polyolefin composition comprising the steps of preparing a masterbatch by mixing and/or masticating an elastomeric polyolefin with a cross-linking co-agent, and optionally an additive, in the presence of a thermoplastic polyolefin; then, cooling the masterbatch obtained in the preceding step at least up to the solidification of the thermoplastic polyolefin; and finally mixing and/or masticating the masterbatch, after the cooling step, with a cross-linking agent and optionally an additive. | 2010-02-25 |
20100048824 | UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITIONS - The present invention relates to a two-component composition comprising a first component and a second component, wherein the first component being a non-aqueous resin composition comprising an unsaturated polyester resin or vinyl ester resin, a transition metal compound selected from a copper, iron, manganese or titanium compound, a potassium compound, and the resin composition contains less than 0.01 mmol cobalt per kg primary resin system and less than 0.01 mmol vanadium per kg primary resin system; and the second component comprises a peroxide compound. | 2010-02-25 |
20100048825 | THERMOPLASTIC RESIN PELLETS AND METHOD FOR PREPARING SAME - The present invention relates to resin pellets which comprises a thermoplastic resin (A) and an oxidation catalyst (B) which is not supported by any carrier, wherein if the peak area in the vicinity of 1715 cm | 2010-02-25 |
20100048826 | Polyphenylene ether oligomer compound, derivatives thereof and use thereof - The present invention provides a bifunctional phenylene ether oligomer compound having a thermosetting functional group at each terminal, an epoxy resin containing the above oligomer compound and a use thereof. That is, it provides a sealing epoxy resin composition for sealing an electric part, an epoxy resin composition for laminates, a laminate, a printed wiring board, a curable resin composition and a photosensitive resin composition. The resins and resin compositions of the present invention are used in electronics fields in which a low dielectric constant, a low dielectric loss tangent and high toughness are required and also used for various uses such as coating, bonding and molding. | 2010-02-25 |
20100048827 | CURING AGENT FOR LOW TEMPERATURE CURE APPLICATIONS - The present invention discloses both amine compositions and amine-epoxy compositions containing N,N′-dimethyl-meta-xylylenediamine. A novel process for producing amines such as N,N′-dimethyl-meta-xylylenediamine, and structurally similar amines, is also disclosed. | 2010-02-25 |
20100048828 | ESTER PRE-EXTENDED EPOXY-TERMINATED VISCOSIFIERS AND METHOD FOR PRODUCING THE SAME - Viscosifiers, especially terminated polymers that have functional terminal groups, the polymers being pre-extended by polyols and being reacted to give polymers that are terminated by other functional groups, are produced. The viscosifiers have a low content in educts or educt descendants that deteriorate the properties of compositions. The formation of high-molecular addition products is considerably reduced or even excluded so that the products obtained have low viscosity and good storage stability. The epoxy-terminated polymer of formula (I) is especially preferred. | 2010-02-25 |
20100048829 | IONIC LIQUIDS FOR SOLUBILIZING POLYMERS - The present invention relates to a liquid composition which comprises at least one polymer and at least one ionic liquid, the cations of which are derived from polycyclic amidine bases, and a process for isolating cellulose from cellulose-containing sources using at least one such ionic liquid. | 2010-02-25 |
20100048830 | Conductive Polymer Films Grafted on Organic Substrates - One aspect of the invention relates to a linker-free, one-step method of grafting polymer films onto organic substrates, and the films obtained by such a method. In certain embodiments, the grafted polymer films are conductive. In certain embodiments, said grafting method utilizes the ability for Friedel-Crafts catalyst to form radical cations from organic substrates. In one embodiment, the method provides poly-3,4-ethylenedioxythiophene (PEDOT) thin films grafted to organic substrates. In other embodiments, the method is applicable to the polymerization of other monomers to yield conducting polymers, such as polyanilines, polypyrroles, polyfurans, polythiophenes and their derivatives. Remarkably, the polymer films grafted by the inventive methods show enormous increases in adhesion strength. Further, in certain embodiments, polymer patterns were easily obtained using the inventive methods and soft lithography techniques. In certain embodiments, well-defined high-density line-and-space patterns were successfully obtained. In certain embodiments, e.g., when the polymer film is conducting, the obtained conducting polymer pattern grafted on common organic substrates can be used for integrated circuitry in flexible electronics. | 2010-02-25 |
20100048831 | POLYURETHANE ADHESIVE - The present invention relates to acrylic compositions capable of bonding directly with an isocyanate-containing composition, e.g. polyurethane, and methods for manufacturing the same. The acrylic compositions of the invention have multifunctional chain transfer agents and/or multifunctional crosslinkers with isocyanate-reactive groups. | 2010-02-25 |
20100048832 | Alkylated 4-Aminobenzyl-4-Aminocyclohexane - Alkylated 4-aminobenzyl-4-aminocyclohexane curing agents that can be used, for example, in polyurea, polyurethane and urea/urethane hybrid elastomeric, epoxy resin, epoxy adhesive, epoxy composites and/or coating compositions and polymeric compositions comprising these curing agents are provided herein. In one embodiment, the curing agent comprises a compound having the following Formula I: | 2010-02-25 |
20100048833 | Mixed Polycycloaliphatic Amines (MPCA) And MPCA Alkylates - Mixed polycycloaliphatic amines (MPCA) and alkylates thereof (MPCA alkylates), methods for making mixed polycycloaliphatic MPCA amines and MPCA alkylates thereof, as well as polymeric compositions, such as spray-applied polyurea coating compositions, comprising said mixed amines MPCA and MPCA alkylates thereof are described herein. In one embodiment, the polymeric composition comprises an isocyanate component, and a resin component comprising an organic compound having the following Formula I: | 2010-02-25 |
20100048834 | CABLE SHEATHING - Cable sheathing on the basis of thermoplastic polyurethane based on the reaction of (a) isocyanates with (b) diols, wherein the diol (b) is based on straight-chain or branched diols (i) having from 16 to 45 carbon atoms in an uninterrupted carbon skeleton. | 2010-02-25 |
20100048835 | SULFONIC ACID GROUP-CONTAINING CARBONACEOUS MATERIAL - A sulfonic acid group-containing carbonaceous material that is useful as a solid acid catalyst for various reactions such as hydration of olefins and acidolysis reaction of hydroperoxide and also useful as a proton conductor material having excellent proton conductivity is provided. In addition, an economical and environmentally friendly method for producing methyl ethyl ketone is provided. A sulfonic acid group-containing carbonaceous material having high catalytic activities for various acid catalyst reactions and also having high proton conductivity can be obtained by carbonization and sulfonation of a phenolic resin. | 2010-02-25 |
20100048836 | FILM-FORMING MATERIAL CONTAINING PHOSPHOROUS - Film-forming materials include resins and/or crosslinkers having a covalently bonded phosphorous atom, the phosphorous atom having at least one covalently bonded oxygen atom. Film-forming resins containing phosphorous can include epoxy, acrylic, polyurethane, polycarbonate, polysiloxane, polyvinyl, polyether, aminoplast, and polyester resins. A process to produce a film-forming resin includes reacting various polymers to incorporate a pendent group comprising a covalently bonded phosphorous atom. Film-forming resins can be used in methods of producing coating compositions. Coating compositions can be used to coat a substrate, such as a metal substrate, by electrodeposition. Applied coatings containing the film-forming resins can be cured to form crosslinked films on substrates. | 2010-02-25 |
20100048837 | System and method for reducing fouling in a reactor - The techniques disclosed provide a treatment method for passivating the interior surface of a polymerization reactor to minimize the formation of a polymer coating on the surface. The passivation is performed using a passivating agent that reacts with adsorbed water to form labile passivation products. Both the passivating agent and passivation products may be easily removed from the reactor prior to polymerization. Other embodiments provide a reactor system with a tank configured to automatically add a passivating agent to the reactor and processes for making polymers using a treated reactor. | 2010-02-25 |
20100048838 | ISOOLEFIN-DIOLEFIN PRODUCTION PROCESS AND APPARATUS THEREFORE - In an isoolefin-diolefin rubber production process (e.g. a butyl rubber production process), the cold rubber slurry produced in the reaction vessel is transported from the reaction vessel to the flash tank during which time the cold slurry may be expressed to separate at least part of the cold liquid reaction medium from the isoolefin-diolefin rubber. The separated cold liquid reaction medium is transported off stream, for example by a mechanical filter, where it can be recycled back into the reaction vessel and/or where it can be used to cool a feed stream or streams of the reaction components. The isoolefin-diolefin rubber and the residual liquid reaction medium are transported to a flash tank for further processing. The ability to separate and recycle cold liquid reaction medium makes the process more economical. In one aspect, the slurry may be transported from the reaction vessel to the flash tank by a self-cleaning fully intermeshing co-rotating twin screw extruder, which helps overcome the problem of plugging due to rubber sticking to the surfaces of the slurry transfer apparatus. | 2010-02-25 |
20100048839 | Novel method for producing water-soluble comb-shaped copolymers - The invention relates to a method for producing a comb-shaped copolymer whose skeleton is of an acrylamide, acrylic acid, acryloyl aminoethanol or dimethyl acrylamide type and on which poly(N-alkyl acrylamide) or poly(N,N-5 dialkyl acrylamide lateral segments are grafted. Said method is characterised in that it consists (a) in producing a telomer poly(N-alkyl acrylamide) or poly(N,N-dialkyl acrylamide) of formula (I) H | 2010-02-25 |
20100048840 | TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND OLEFINS USING THE SAME - Disclosed herein is a group IV transition metal catalyst for producing an ethylene homopolymer or an ethylene-olefin copolymers, having high catalytic activity, which includes a cyclopentadiene derivative and one or more anionic ligands having an aryl group substituted with an aryl derivative at an ortho-position thereof around a transition metal, the ligands not being crosslinked to each other, a catalyst system including the group IV transition metal catalyst and an aluminoxane cocatalyst or a boron compound cocatalyst, and a method of producing ethylene homopolymers or ethylene-olefin copolymers using the catalyst system. | 2010-02-25 |
20100048841 | PHENOL-HETEROCYCLIC LIGANDS, METAL COMPLEXES, AND THEIR USES AS CATALYSTS - Ligands, compositions, and metal-ligand complexes that incorporate phenol-heterocyclic compounds are disclosed that are useful in the catalysis of transformations such as the polymerization of monomers into polymers. The catalysts have high performance characteristics, including high comonomer incorporation into ethylene/olefin copolymers, where such olefins are for example, 1-octene, propylene or styrene. The catalysts particularly polymerize styrene to form polystyrene. | 2010-02-25 |
20100048842 | METAL-LIGAND COMPLEXES AND CATALYSTS - The present invention generally relates to metal-ligand complexes, catalysts comprising or prepared from the metal-ligand complexes, processes of catalyzing olefin polymerization reactions with the catalysts to prepare polyolefins, polyolefins prepared thereby, processes of making the metal-ligand complexes and catalysts, and intermediate compounds useful therefor. | 2010-02-25 |
20100048843 | CATALYST COMPOSITIONS AND POLYOLEFINS FOR EXTRUSION COATING APPLICATIONS - This invention relates to the field of olefin polymerization catalyst compositions, and methods for the polymerization and copolymerization of olefins, including polymerization methods using a supported catalyst composition. In one aspect, the present invention encompasses a catalyst composition comprising the contact product of a first metallocene compound, a second metallocene compound, at least one chemically-treated solid oxide, and at least one organoaluminum compound. The new resins were characterized by useful properties in impact, tear, adhesion, sealing, extruder motor loads and pressures at comparable melt index values, and neck-in and draw-down. | 2010-02-25 |
20100048844 | THIOCARBONYLTHIO COMPOUND AND FREE RADICAL POLYMERIZATION EMPLOYING THE SAME - A thiocarbonylthio compound and free radical polymerization employing the same. The thiocarbonylthio compound is represented by formula (I) or (II): | 2010-02-25 |
20100048845 | Hyperbranched polymer and method for producing the same - Disclosed is a novel optically stable hyperbranched polymer whose molecular terminal can be derivatized with various compounds; and a method for producing such a polymer. Specifically disclosed is a hyperbranched polymer having a structure represented by Formula (1) | 2010-02-25 |
20100048846 | WATER/OIL REPELLENT COMPOSITION, METHOD FOR PRODUCTION THEREOF, AND ARTICLE - To provide a water/oil repellent composition which can impart water/oil repellency to a surface of an article without having its texture deteriorated, and has excellent durability against washing and stability, a method for producing such a composition, and an article treated with such a water/oil repellent composition. | 2010-02-25 |
20100048847 | Contact Lens - A contact lens formed of a composition comprising the reaction product of: A) at least 10 weight percent, based on the total composition weight excluding solvent, of at least one silicone-containing monomer of the formula I: where n is from 1 to 3, m is from 9 to 15, each a independently is C | 2010-02-25 |
20100048848 | PROCESS FOR PRODUCING POLYMER FOR SEMICONDUCTOR LITHOGRAPHY - To provide a method for producing a polymer for semiconductor lithography which can attain high uniformity in the polymer from lot to lot. | 2010-02-25 |
20100048849 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP - A diamine compound of formula (I) is proposed as well as polymers, copolymers, polyamic acids, polyamic acid esters, or polyimides based on such compound. | 2010-02-25 |
20100048850 | METHOD FOR THE SYNTHESIS OF ACRYLONITRILE FROM GLYCEROL - The invention relates to a novel way to synthesize acrylonitrile from a renewable raw material and more particularly relates to a method for producing acrylonitrile by the ammoxidation of glycerol in gaseous phase. The method can be implemented in a single step, or the glycerol can be previously submitted to a dehydration step. The acrylonitrile thus obtained meets the requirements of green chemistry. | 2010-02-25 |
20100048851 | Polycarbonate and production method thereof - There is provided a polycarbonate which is excellent in both surface slipperiness and abrasion resistance. | 2010-02-25 |
20100048852 | High impact poly(urethane urea) polysulfides - The present invention relates to a sulfur-containing polyureaurethane and a method of preparing the polyureaurethane. The sulfur-containing polyureaurethane has a refractive index of at least 1.57, an Abbe number of at least 32 and a density of less than 1.3 grams/cm | 2010-02-25 |
20100048853 | POLYETHERIMIDE POLYMER FOR USE AS A HIGH HEAT FIBER MATERIAL - Various embodiments of polymer fibers comprising a high heat polymer and process for making the polymer fibers are provided. In one embodiment, synthetic polymer fibers comprise polyetherimide polymer that is substantially free of foreign particulate matter greater than about 100 microns in size. A process for producing polymer fiber includes melting polymer comprising polyetherimide to a melt temperature that ranges from about 180-500° C. to form a molten polymer; passing the polyetherimide that is substantially free of foreign particulate matter above about 100 microns in size, through a spinneret comprising a plurality of hole openings to produce a fiber bundle; and cooling the fiber bundle with a cooling medium having a temperature that ranges from about 0° C. to about 80° C. | 2010-02-25 |
20100048854 | POLYCARBONATE RESIN AND MANUFACTURING PROCESS THEREOF - A polycarbonate resin which shows a high content of biogenic matter and has excellent heat resistance, heat stability and moldability, and a manufacturing process thereof. The polycarbonate resin contains a recurring unit represent by the following formula (1) as the major constituent, and has (i) a specific viscosity of a solution prepared by dissolving 0.7 g of the resin in 100 ml of methylene chloride at 20° C. of 0.20 to 0.45, (ii) a glass transition temperature (Tg) of 150 to 200° C., and (iii) a 5% weight loss temperature (Td) of 330 to 400° C. | 2010-02-25 |
20100048855 | Optical Lens - Disclosed is an optical lens which can be produced by injection molding on an industrial scale and which has a high refractive index, a low Abbe's number, a low birefringence index, a high transparency and a high glass transition temperature. The optical lens can be produced by injection molding of a polycarbonate resin (preferably having a reduced viscosity of 0.2 dl/g or higher and a glass transition temperature of 120 to 160° C.), wherein the polycarbonate resin is produced by reacting a diol component comprising 99 to 51 mol % of 9,9-bis(4-(2-hydroxyethoxy)phenyl)fluorene and 1 to 49 mol % of bisphenol A with a carbonate diester. It becomes possible to produce an optical lens preferably having a refractive index of 1.60 to 1.65, an Abbe's number of 30 or smaller, a birefringence index of 300 nm or lower and an all light transmittance of 85.0% or higher. | 2010-02-25 |
20100048856 | PROCESS FOR THE SYNTHESIS OF ETHERS OF AROMATIC ACIDS - Ethers of aromatic acids are produced from halogenated aromatic acids in a reaction mixture containing a copper (I) or copper (II) source and a Schiff base ligand that coordinates to copper. | 2010-02-25 |
20100048857 | THERMOPLASTIC POLYPHENOXYQUINOXALINE AND METHOD OF PREPARING THE SAME - The manufacture of polyetherquinoxalines may be accomplished by polymerization of quinoxaline and related monomers with a bisphenol under aromatic nucleophilic substitution reaction conditions. A method of manufacture includes contacting a substituted or unsubstituted quinoxaline having replaceable groups at the 2,3 positions with a bisphenol or a bisphenol derivative under aromatic nucleophilic substitution reaction conditions. The resulting polyetherquinoxalines contain quinoxaline groups joined by ether linkages at the 2 and 3 positions of the quinoxaline groups. In one example, the polyetherquinoxaline has a formula represented as | 2010-02-25 |
20100048858 | POLY(P-XYLYLENE)-BASED POLYMER HAVING LOW DIELECTRIC CONSTANT AND LOW-LOSS PROPERTY AND INSULATING MATERIAL, PRINTED CIRCUIT BOARD AND FUNCTIONAL ELEMENT USING THE SAME - The present invention relates to a poly(p-xylylene)-based polymer having a low dielectric constant suitable for low loss dielectrics (LLD), and an insulating material, a printed circuit board and a functional element using the same. More particularly, the poly(p-xylylene)-based polymer includes at least one repeat unit expressed by the following formula (1): | 2010-02-25 |
20100048859 | PDC-LACTIC ACID COPOLYESTER AND MOLDED PRODUCT THEREOF - A polyester containing a biomass-derived material in a repeating unit structure and having all of sufficient mechanical strength, easy mold processability into a molded product such as fiber or film, and biodegradability, is provided. | 2010-02-25 |
20100048860 | CONTINUOUS PROCESS FOR THE EXTRACTION OF POLYAMIDE-6 - A continuous process is disclosed for the extraction of monomeric caprolactam and its oligomers as the raw polymer product obtained in the polymerization of polyamide-6 in which no fresh water, but processing water or previously used extraction water is used for the granulation. | 2010-02-25 |
20100048861 | POLYIMIDE RESIN AND LIQUID CRYSTAL ALIGNMENT LAYER AND POLYIMIDE FILM USING THE SAME - Disclosed is a polyimide resin, which is colorless and transparent and has superior properties, including mechanical properties and heat stability, and thus is usable in various fields, including semiconductor insulating films, TFT-LCD insulating films, transparent electrode films, passivation films, liquid crystal alignment layers, optical communication materials, protective films for solar cells, and flexible display substrates. Also, a liquid crystal alignment layer and a polyimide film using the polyimide resin are provided. | 2010-02-25 |
20100048862 | Ferroportin1 nucleic acids, proteins, antibodies and methods - Positional cloning has been carried out to identify the gene responsible for the hypochromic anemia of the zebrafish mutant weissherbst. The gene, ferroportin1, encodes a novel multiple-transmembrane domain protein, expressed in the yolk sac. Zebrafish ferroportin1 is required for the transport of iron from maternally-derived yolk stores to the circulation, and functions as an iron exporter when expressed in | 2010-02-25 |
20100048863 | GROWTH FACTOR WHICH ACTS THROUGH ERB B-4 RTK - A method of diagnosing a disease or syndrome associated with disregulation of Neuregulin-4 (NRG-4), Aa novel ErbB-4 ligand, referred to herein as Neuregulin-4 (NRG-4)in a subject is disclosed. The method comprising: (a) obtaining a sample from a subject; (b) incubating the sample with at least one oligonucleotide or oligonucleotide analog of at least bases, said oligonucleotide or oligonucleotide analog capable of hybridizing to a portion of a polynucleotide strand encoding NRG-4 to thereby diagnosing the disease, condition or syndrome associated with disregulation of NRG-4. | 2010-02-25 |
20100048864 | BACTERIAL LEADER SEQUENCES FOR INCREASED EXPRESSION - Compositions and methods for improving expression and/or secretion of a polypeptide of interest in a host cell are provided. Compositions including a coding sequence for a bacterial secretion signal peptide are provided. The compositions of the invention are useful for increasing accumulation of properly processed proteins in the periplasmic space of a host cell, or for increasing secretion of properly processed proteins. In particular, isolated secretion signal peptide-encoding nucleic acid molecules are provided. Additionally, amino acid sequences corresponding to the nucleic acid molecules are encompassed. The present invention provides for isolated nucleic acid molecules including nucleotide sequences encoding the amino acid sequences shown in SEQ ID NO:2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, and 24, and the nucleotide sequences set forth in SEQ ID NO:1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, and 23, as well as variants and fragments thereof. | 2010-02-25 |
20100048865 | MICROWAVE-ASSISTED PEPTIDE SYNTHESIS - An instrument and method for accelerating the solid phase synthesis of peptides are disclosed. The method includes the steps of deprotecting a protected first amino acid linked to a solid phase resin by admixing the protected linked acid with a deprotecting solution in a microwave transparent vessel while irradiating the admixed acid and solution with microwaves, activating a second amino acid, coupling the second amino acid to the first acid while irradiating the composition in the same vessel with microwaves, and cleaving the linked peptide from the solid phase resin by admixing the linked peptide with a cleaving composition in the same vessel while irradiating the composition with microwaves. | 2010-02-25 |
20100048866 | WATER-SOLUBLE PHOSPHINOTHIOL REAGENTS - Water soluble reagents and methods for the formation of an amide bond between a phosphinothioester and an azide in an aqueous medium. The phosphinothioester is generated using a water-soluble phosphinothiol reagent. This reaction allows formation of an amide bond between a wide variety of chemical species including amino acids, peptides or protein fragments in an aqueous solution. Of particular interest, this reaction allows for the formation of an amide bond in a physiological setting. In a specific embodiment, this invention provides reagents and methods for peptide ligation in an aqueous medium. The reaction eliminates the need for a cysteine residue and is traceless leaving no residual atoms in the ligated peptide product. | 2010-02-25 |
20100048867 | DEVICE AND PROCESS FOR PURIFYING NUCLEIC ACIDS - An apparatus for purifying nucleic acids by negative chromatography is disclosed, which comprises a hollow body with an opening, respectively, at the top and at the bottom end, said hollow body containing a stationary solid phase, characterized in that the stationary phase contains at least 2 different chromatography resins, such as size e.g. exclusion gel filtration materials (SEC materials), as well as a method for purifying nucleic acids and the use of the apparatus. | 2010-02-25 |
20100048868 | Polypeptides Having Binding Affinity for Her2 - A polypeptide is provided, which has a binding affinity for HER2 and which is related to a domain of staphylococcal protein A (SPA) in that the sequence of the polypeptide corresponds to the sequence of the SPA domain having from 1 to about 20 substitution mutations. Nucleic acid encoding the polypeptide, as well as expression vector and host cell for expressing the nucleic acid, are also provided. Also provided is the use of such a polypeptide as a medicament, and as a targeting agent for directing substances conjugated thereto to cells overexpressing HER2. Methods, and kits for performing the methods, are also provided, which methods and kits rely on the binding of the polypeptide to HER2. | 2010-02-25 |
20100048869 | AGENT COMPRISING G-CSF FOR PREVENTION AND TREATMENT OF DIABETIC PERIPHERAL NEUROPATHY - Disclosed is an agent for preventing and treating diabetic peripheral neuropathy including a granulocyte colony stimulating factor (G-CSF) as an active ingredient, which is able to improve nerve conduction velocity and pain sensitivity by regenerating blood vessels in peripheral tissues and rehabilitating damaged nerve tissues. | 2010-02-25 |
20100048870 | IDENTIFYING COMPONENTS OF A NETWORK HAVING HIGH IMPORTANCE FOR NETWORK INTEGRITY - A computer system ( | 2010-02-25 |
20100048871 | Biosynthetic Polypeptides Utilizing Non-Naturally Encoded Amino Acids - Modified biosynthetic polypeptide molecules, methods for manufacturing, and uses thereof are provided. | 2010-02-25 |
20100048872 | METHODS FOR MAKING PROTEINS CONTAINING FREE CYSTEINE RESIDUES - The present invention relates to novel methods of making soluble proteins having free cysteines in which a host cell is exposed to a cysteine blocking agent. The soluble proteins produced by the methods can then be modified to increase their effectiveness. Such modifications include attaching a PEG moiety to form pegylated proteins. | 2010-02-25 |
20100048873 | METHOD OF OBTAINING PLANT PROTEIN FRACTIONS WITH A MEDIUM MOLECULAR WEIGHT, PLANT PROTEIN FRACTION, AND ITS USE - A method of preparing a coagulated plant protein fraction with a medium molecular weight of between 14 to 97, by providing fruit juice in aqueous solution; precipitating a high-molecular-weight plant protein fraction whose bulk has a molecular weight of from above 100 to 600, by adjusting an acidic pH and/or a temperature above room temperature, and mechanically separating the fraction precipitated thus; precipitating a medium-molecular-weight coagulated plant protein fraction under warm conditions by treating, at pH 2 to 7, and between 60 to 90° C., the solution obtained after separation of the high-molecular-weight plant protein fraction and mechanically separating the medium-molecular-weight coagulated plant protein fraction with a molecular weight of between approximately 14 to 97, with the bulk of the molecular weight distribution being between 20 to 60. The plant protein fraction is usable as foodstuff, food additive, additive in pharmaceuticals, animal feed, in cosmetics, as industrial protein, as adhesive. | 2010-02-25 |
20100048874 | Colour reduction in canola protein isolate - In the recovery of canola protein isolates from canola oil seeds steps are taken to inhibit the formation of colouring components and to reduce the presence of materials tending to form colouring components, to obtain a lighter and less yellow canola protein isolate. | 2010-02-25 |
20100048875 | Soluble Canola Protein Isolate Production from PMM ("C307") - A soluble canola protein isolate is prepared from canola protein micellar mass by solubilizing the protein micellar mass in a calcium salt solution, preferably a calcium chloride solution, followed by dilution of the resulting canola protein solution. Following removal of the precipitate phytic acid, the aqueous canola protein solution is concentrated, optionally diafiltered, and acidified to a pH of about 2.5 to 4.0 to produce an acidified clear canola protein solution, which may be concentrated, subjected to a colour removal step and dried. The canola protein isolate so formed is soluble, transparent and heat stable in an acid aqueous environment and also is soluble at natural pH, without precipitation of protein. | 2010-02-25 |
20100048876 | CHROMATOGRAPHY LIGAND COMPRISING DOMAIN C FROM STAPHYLOCOCCUS AUREUS PROTEIN A FOR ANTIBODY ISOLATION - The present invention relates to a chromatography ligand, which comprises Domain C from | 2010-02-25 |
20100048877 | NOVEL MULTIVALENT IMMUNOGLOBULINS - The present invention provides a multivalent immunoglobulin or part thereof binding specifically to at least two cell surface molecules of a single cell with at least one modification in at least one structural loop region of said immunoglobulin determining binding to an epitope of said cell surface molecules wherein the unmodified immunoglobulin does not significantly bind to said epitope, its use and methods for producing it. | 2010-02-25 |
20100048878 | HUMAN GENE - The present invention provides novel human genes, for example a novel human gene comprising a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:1. The use of the genes makes it possible to detect the expression of the same in various tissues, analyze their structures and functions, and produce the human proteins encoded by the genes by the technology of genetic engineering. Through these, it becomes possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the genes, for example hereditary diseases and cancer, and diagnose and treat such diseases. | 2010-02-25 |
20100048879 | MULTIMERISED HIV FUSION INHIBITORS - There are provided multimeric fusion proteins exhibiting anti-viral activity. The fusion proteins comprise the HR2 region of the ectodomain of the human immunodeficiency virus gp41 protein which is fused to a multimerisation domain peptide such as a trimerisation domain derived from tetranectin. The multimerised fusion proteins may be used as HIV fusion inhibitors in the treatment of AIDS. | 2010-02-25 |
20100048880 | Starch Binding Domain and Use Thereof - The present invention relates to a starch binding domain, a recombinant protein and a complex thereof. The present invention also relates to a method for separating a recombinant protein comprising a starch binding domain of the present invention. | 2010-02-25 |
20100048881 | AZODICARBOXYLIC ACID BIS(2-ALKOXYETHYL) ESTER COMPOUND, AND PRODUCTION INTERMEDIATE THEREOF - Provided is an industrially safe and useful azodicarboxylic acid bis(2-alkoxyethyl) ester compound that is useful for the Mitsunobu reaction in which it is used in combination with a phosphorus compound to carry out a dehydration condensation reaction, and also useful as an oxidizing agent, and a starting material for various synthetic processes. Also provided are a production intermediate of the above-described compound, and methods for producing these compounds. An azodicarboxylic acid bis(2-alkoxyethyl) ester compound represented by formula (1); | 2010-02-25 |
20100048882 | Novobiocin Analogues as Anticancer Agents - Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present invention are useful as heat shock protein 90 inhibitors, and may be used as anticancer and neuroprotective agents. | 2010-02-25 |
20100048883 | METHOD FOR PURIFYING RNA ON A PREPARATIVE SCALE BY MEANS OF HPLC - The application describes a method for the preparative purification of RNA, which method is distinguished in that the RNA is purified by means of HPLC using a porous reversed phase as the stationary phase. The use of the porous reversed phase in this HPLC method is also described. | 2010-02-25 |
20100048884 | SOLVO-THERMAL HYDROLYSIS OF CELLULOSE - The invention relates to a process for hydrolyzing cellulose, comprising: (a) contacting cellulose with a fluid mixture comprising supercritical CO | 2010-02-25 |
20100048885 | Immunostimulating Polysaccharides Isolated From Curcuma Xanthorrhiza and Manufacturing Method Thereof - The present invention provides a method for manufacturing polysaccharides isolated from | 2010-02-25 |
20100048886 | PROCESS FOR PRODUCING SILYLATED PULLULAN AND COSMETIC PREPARATION - The present invention provides a process for producing silylated pullulan, which features reacting pullulan with N,O-bistrimethylsilylacetamide by using, as a reaction medium, only one of N-methyl-2-pyrrolidone and N-ethyl-2-pyrrolidone or a mixed solvent of both of them. Compared with conventional processes, the process according to the present invention can produce high-purity silylated pullulan simply, easily and efficiency. | 2010-02-25 |
20100048887 | COMPOUNDS INCLUDING AN ANTI-INFLAMMATORY PHARMACORE AND METHODS OF USE - This invention provides novel compounds comprising the following anti-inflammatory pharmacore: | 2010-02-25 |
20100048888 | Lipid Nanoparticle Based Compositions and Methods for the Delivery of Biologically Active Molecules - The present invention relates to novel cationic lipids, transfection agents, microparticles, nanoparticles, and short interfering nucleic acid (siNA) molecules. The invention also features compositions, and methods of use for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity in a subject or organism. Specifically, the invention relates to novel cationic lipids, microparticles, nanoparticles and transfection agents that effectively transfect or deliver biologically active molecules, such as antibodies (e.g., monoclonal, chimeric, humanized etc.), cholesterol, hormones, antivirals, peptides, proteins, chemotherapeutics, small molecules, vitamins, co-factors, nucleosides, nucleotides, oligonucleotides, enzymatic nucleic acids, antisense nucleic acids, triplex forming oligonucleotides, 2,5-A chimeras, dsRNA, allozymes, aptamers, decoys and analogs thereof, and small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), short hairpin RNA (shRNA), and RNAi inhibitor molecules, to relevant cells and/or tissues, such as in a subject or organism. Such novel cationic lipids, microparticles, nanoparticles and transfection agents are useful, for example, in providing compositions to prevent, inhibit, or treat diseases, conditions, or traits in a cell, subject or organism. The compositions described herein are generally referred to as formulated molecular compositions (FMC) or lipid nanoparticles (LNP). | 2010-02-25 |
20100048889 | DI-(1-Imidazole) metal phthalocyanine compound, composition comprising the same and preparation method thereof - Disclosed herein are a di-(1-vinylimidazole) metal phthalocyanine compound in which 1-vinylimidazoles as ligands are included in a phthalocyanine having a metal, a composition comprising the same and a preparation method thereof. The di-(1-vinylimidazole) metal phthalocyanine compound has an excellent UV blocking effect together with low surface resistance and is prepared but by charging a powder phase with nitrogen, not by dissolving raw materials in an organic solvent as in the prior art. | 2010-02-25 |
20100048890 | CONJUGATED SMALL MOLECULES - Provided herein are linker compounds and conjugates that include the linker compounds. In one embodiment, the linker compounds comprise 2 or 3 residues of 6-aminohexanoic acid and optionally 7-10 residues of polyethyleneglycol (PEG). The linker compounds are useful in forming conjugates with one or more components useful in biopharmaceutical or bioanalytical applications. In particular, the biopharmaceutically useful compounds are kinase inhibitors. The conjugates described herein have utility in a variety of diagnostic, separation, and therapeutic applications. | 2010-02-25 |
20100048891 | METASUBSTITUTED THIAZOLIDINONES, THEIR MANUFACTURE AND USE AS A DRUG - Thiazolidinones of general formula (I) | 2010-02-25 |
20100048892 | ANTIOXIDANT INFLAMMATION MODULATORS: OLEANOLIC ACID DERIVATIVES WITH AMINO AND OTHER MODIFICATIONS AT C-17 - This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: | 2010-02-25 |
20100048893 | Substituted arylalkanoic acid derivatives and use thereof - A compound represented by the formula (I): | 2010-02-25 |
20100048894 | PHOSPHINE TRANSITION METAL COMPLEX, PROCESS FOR PRODUCING SAME, AND ANTICANCER AGENT - An anticancer agent having a novel chemical structure and high anticancer activity is provided. A phosphine transition metal complex of general formula (1) and an anticancer agent containing the complex are disclosed. | 2010-02-25 |
20100048895 | Process for Preparing Heterocyclic Derivatives - The present invention relates to a novel process, useful for preparing key intermediates of formula (I) in the synthesis of various compounds, among them compounds which are potent and specific antagonists of D3 receptors, | 2010-02-25 |
20100048896 | PROCESS FOR THE MANUFACTURE OF A CRYSTALLINE PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND - The present invention relates to a novel process for the industrial manufacture of polymorph B of N-{2-Fluoro-5-[3-(thiophene-2-carbonyl)-pyrazolo[1,5-a]pyrimidin-7-yl]-phenyl}-N-methyl-acetamide. | 2010-02-25 |
20100048897 | PROCESS FOR THE PREPARATION OF SILDENAFIL AND INTERMEDIATES THEREOF - The present invention discloses a process for preparing sildenafil and its intermediates having the structures outlined below: | 2010-02-25 |
20100048898 | Process for Synthesizing 7-Alkynyl-4- Aminoquinazolines and a Related Intermediate - A process for synthesizing 7-alkynyl-4-aminoquinazolines from 7-haloquinazolines is disclosed. In one specific synthesis, 4-[N-3-chloro-4-fluorophenyl)]-7-[3-methyl-3-(4-methyl-1-piperazinyl)-1-butynyl]-6-[N-methyl acrylamide]quinazoline is prepared from 7-chloro-6-nitro-3H-quinazolin-4-one. Also disclosed is an intermediate useful in the syntheses of 7-alkynyl-4-ammoquinaozolines and a process for making the intermediate. The 7-alkynyl-4-aminoquinaozolines prepared by processes of the invention are useful as pharmaceutically active compounds. | 2010-02-25 |
20100048899 | PROCESS FOR PREPARING ROSUVASTATIN CALCIUM - The present invention relates to an improved process for preparing Rosuvastatin calcium of Formula I. | 2010-02-25 |
20100048900 | AGENT FOR TREATMENT OF VASCULAR LEAKS - The invention relates to an agent which contains ectoines for the prophylactic or therapeutic treatment of endothelial function disturbances, in particular the VLS. | 2010-02-25 |
20100048901 | NOVEL CURCUMIN DERIVATIVE - The present invention provides a novel compound that is structurally similar to curcumin and has a suppressive effect on Aβ aggregation, a degradative effect on Aβ aggregates, an inhibitory effect on β-secretase, and a protective effect on neurons. The novel compound is a compound represented by the following general formula (Ia) or a salt thereof: | 2010-02-25 |
20100048902 | DI-(4-vinylpyridine) metal phthalocyanine compound, composition comprising the same and preparation method thereof - Disclosed herein are a di-(4-vinylpyridine) metal phthalocyanine compound in which 4-vinylpyridines as ligands are included in a phthalocyanine having a metal, a composition comprising the same and a preparation method thereof. The di-(4-vinylpyridine) metal phthalocyanine compound has an excellent UV blocking effect together with low surface resistance and is prepared but by charging a powder phase with nitrogen, not by dissolving raw materials in an organic solvent as in the prior art. | 2010-02-25 |
20100048903 | Method For Producing Azoniaspironortropine Esters And Nortropan-3-One Compounds - The present technology relates to an improved one-stage method for producing azoniaspironortropine esters such as trospium chloride by reacting an endonortropine compound with an organic dihalogen compound and an a-hydroxycarboxylic acid in the presence of a base and 1,1′ carbonyldiimidazole or 1,1′ thiocarbonyldiimidazole or thionyldiimidazole. The present technology also relates to an improved method for producing nortropan-3-one compounds or their hydrohalides (such as N-benzyltropanone hydrochloride) by reacting an amine and a protected dialdehyde with a basic aqueous solution of 1,3-acetone dicarboxylic acid. | 2010-02-25 |
20100048904 | DIBENZORYLENETETRACARBOXIMIDES AS INFRARED ABSORBERS - Dibenzorylenetetracarboximides of the general formula I | 2010-02-25 |
20100048905 | Novel Opiate Reduction Utilizing Catalytic Hydrogen Transfer Reaction - An improved opiate synthesis scheme is provided. An improvement to the oxidation of oripavine and oripavine derivatives comprises the in-situ formation of the peroxacids required to oxidize the oripavine and oripavine derivatives to form an intermediate. An improvement to the reduction of the intermediate to form oxycodone and oxycodone derivatives comprises reduction utilizing a hydrogen transfer reagent. These improvements allow the production of oxycodone and oxycodone derivatives without isolation of the intermediate, providing a one-pot synthesis method. | 2010-02-25 |
20100048906 | Preparation of Substituted Morphinan-6-Ones and Salts and Intermediates Thereof - The present invention is directed to processes for the synthesis of morphinan-6-ones and salts, intermediates, and analogs thereof. | 2010-02-25 |
20100048907 | INDAZOLAMIDES WITH ANALGESIC ACTIVITY - The present invention relates to compounds of formula (II) | 2010-02-25 |
20100048908 | Process for Remifentanil Synthesis - A process for synthesizing remifentanil or carfentanil, as well as intermediates for use in the preparation of a synthetic opiate or opioid compound by alkylating a substituted 4-piperidine in the presence of a base to form an intermediate that is further alkylated with an electrophilic alkylating agent and acylated to produce the compound. | 2010-02-25 |
20100048909 | Process for production of optically active-3-amino-2-hydroxypropionic cyclopropylamide derivatives and salts thereof - An objective of the present application is to provide an industrially practicable method for producing an optically-active 3-amino-2-hydroxypropionic cyclopropylamide derivative or salt thereof from an inexpensive easily-available starting material. The derivative or salt thereof is useful as an intermediate for a medicine. It is also intended by the present application to provide a useful intermediate of the derivative. The objective is attained by the following method. First, an easily-available 2-halo-3-oxopropionic acid derivative is asymmetrically reduced, and then epoxidated to produce an optically-active epoxycarboxylic acid derivative. Next, the derivative is converted into an optically-active epoxyamide derivative by reaction with cyclopropylamine, and then reacted with a nitrile to obtain an optically-active oxazolinamide derivative. Subsequently, selective acid solvolysis of the oxazoline skeleton gives the optically-active 3-amino-2-hydroxypropionic cyclopropylamide derivative or salt thereof. | 2010-02-25 |
20100048910 | PROCESS FOR PREPARING ISOXAZOLE COMPOUNDS - A process for preparing isoxazole compounds of formula I: | 2010-02-25 |
20100048911 | ANTIOXIDANT INFLAMMATION MODULATORS: NOVEL DERIVATIVES OF OLEANOLIC ACID - Disclosed herein are novel oleanolic acid derivatives. Methods of preparing these compounds are also disclosed. The oleanolic acid derivatives of this invention may be used for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress. | 2010-02-25 |
20100048912 | Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens, In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity - Described are steroidal C-17 benzoazoles, pyrimidinoazoles (azabenzoazoles) and diazines. Methods for their synthesis are also described, which include methods having a step of nucleophilic vinylic “addition-elimination” substitution reaction of 3β-acetoxy-17-chloro-16-formylandrosta-5,16-diene or analogs thereof and benzoazole or pyrimidinoazole nucleophiles and methods having a palladium catalyzed cross-coupling reaction of 17-iodoandrosta-5,16-dien-3β-ol or analogs thereof with tributylstannyl diazines. The compounds are potent inhibitors of human CYP17 enzyme as well as potent antagonists of both wild type and mutant androgen receptors (AR). The compounds are useful for the treatment of human prostate cancer. | 2010-02-25 |
20100048913 | Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity - Described are steroidal C-17 benzoazoles, pyrimidinoazoles (azabenzoazoles) and diazines. Methods for their synthesis are also described, which include methods having a step of nucleophilic vinylic “addition-elimination” substitution reaction of 3β-acetoxy-17-chloro-16-formylandrosta-5,16-diene or analogs thereof and benzoazole or pyrimidinoazole nucleophiles and methods having a palladium catalyzed cross-coupling reaction of 17-iodoandrosta-5,16-dien-3β-ol or analogs thereof with tributylstannyl diazines. The compounds are potent inhibitors of human CYP17 enzyme as well as potent antagonists of both wild type and mutant androgen receptors (AR). The compounds are useful for the treatment of human prostate cancer. | 2010-02-25 |
20100048914 | Novel C-17-Heteroaryl Steroidal Cyp17 Inhibitors/Antiandrogens, In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity - Described are steroidal C-17 benzoazoles, pyrimidinoazoles (azabenzoazoles) and diazines. Methods for their synthesis are also described, which include methods having a step of nucleophilic vinylic “addition-elimination” substitution reaction of 3β-acetoxy-17-chloro-16-formylandrosta-5,16-diene or analogs thereof and benzoazole or pyrimidinoazole nucleophiles and methods having a palladium catalyzed cross-coupling reaction of 17-iodoandrosta-5,16-dien-3β-ol or analogs thereof with tributylstannyl diazines. The compounds are potent inhibitors of human CYP 17 enzyme as well as potent antagonists of both wild type and mutant androgen receptors (AR). The compounds are useful for the treatment of human prostate cancer. | 2010-02-25 |
20100048915 | METHOD FOR PREPARING MEDETOMIDINE AND ITS SALTS. - The invention provides an improved, highly efficient method for preparing Medetomidine, and its salts, in particular its pharmaceutically acceptable salts. The method utilizes the high reactivity of halogenated imidazoles towards transmetalation with Grignard reagents and the subsequent reaction with 2,3-dimethylbenzaldehyde. | 2010-02-25 |
20100048916 | HIGH-PURITY TEXAPHYRIN METAL COMPLEXES - Disclosed herein are the methods and compositions for the improved synthesis of texaphyrin metal complexes. The improved synthesis results in high-purity compositions of texaphyrin metal complexes in which more than about 98% of the texaphyrin metal complexes in the composition have the same structure and/or the same molecular weight. Further described herein are pharmaceutical compositions comprising such high-purity compositions, and the use of such high-purity compositions in the treatment of cancer and cardiovascular diseases and disorders. | 2010-02-25 |
20100048917 | PREPARATION OF ALKYL-SUBSTITUTED 2-DEOXY-2-FLUORO-D-RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES - The present invention provides (i) a process for preparing a 2-deoxy-2-fluoro-2-methyl-D-ribonolactone derivative, (ii) conversion of the lactone to nucleosides with potent anti-HCV activity, and their analogues, and (iii) a method to prepare the anti-HCV nucleosides containing the 2-deoxy-2-fluoro-2-C-methyl-β-D-ribofuranosyl nucleosides from a preformed, preferably naturally-occurring, nucleoside. | 2010-02-25 |
20100048918 | Method of manufacturing vinylethylene carbonate - Provided is a method of manufacturing vinylethylene carbonate. The method includes synthesizing vinylethylene carbonate (VEC) by reaction of 3,4-dihydroxy-1-butene (3,4-DHB) and dialkyl carbonate using a base catalyst, and refining the VEC. | 2010-02-25 |
20100048919 | Method for Preparing Crystalline 3-0-Alkyl-Ascorbic Acid - The present invention relates to a method for preparing 3-O-substituted ascorbic acid derivatives represented by formula 1, in which 5,6-O-isopropylidene ascorbic acid is reacted with a halide in an organic solvent in the presence of the anion exchange resin absorbed with multi-iodine anions and then deprotected. The method of the present invention has an advantage of providing a target compound with high purity and high yield by finishing the reaction within a short period of time at room temperature. | 2010-02-25 |
20100048920 | Preparation of (+)-Catechin, (-)-Epicatechin, (-)-Catechin, and (+)-Epicatechin and Their 5,7,3',4'-Tetra-O-Benzyl Analogues - Processes for preparing racemic mixtures of 5,7,3′,4′-tetra-O-benzyl-(±)-catechin and (±)-epicatechin involves (i) condensing 2-hydroxy-4,6-bis(benzyloxy)-acetophenone and 3,4-bis(benzyloxy)benzaldehyde, cyclizing the resulting compound, oxidizing the resulting compound; (ii) dihydroxylating (E)-3-(3′,4′-bis(benzyloxy)phenyl)prop-2-ene-1-ol and reducing the 1,2-diol; or (iii) coupling 3,5-bis(benzyloxy)phenol with (E)-3,5-bis(benzyloxy)-2-(3′,4′-bis(benzyloxy)phenyl)allyl)phenol and cyclizing the resulting chalcone. | 2010-02-25 |
20100048921 | PHARMACEUTICALLY ACTIVE COMPOUNDS - This invention relates to pharmaceutically active compounds consisting of an isoflavone or isoflavone-glycoside and an amino acid, a peptide or peptide derivate with 2 to 5 amino acids which is covalently bonded to these, as well as pharmaceutically acceptable salts or solvates of these compositions as well as to the use of those substances for the production of pharmaceutical compositions, in particular for the treatment of thrombocyte aggregation and tumor therapy. | 2010-02-25 |