08th week of 2014 patent applcation highlights part 36 |
Patent application number | Title | Published |
20140051119 | FUNGAL BETA-XYLOSIDASE VARIANTS - The present invention provides fungal xylanase and/or beta-xylosidase enzymes suitable for use in saccharification reactions. The present application further provides genetically modified fungal organisms that produce xylanase and/or beta-xylosidases, as well as enzyme mixtures exhibiting enhanced hydrolysis of cellulosic material to fermentable sugars, enzyme mixtures produced by the genetically modified fungal organisms, and methods for producing fermentable sugars from cellulose using such enzyme mixtures. | 2014-02-20 |
20140051120 | HUMANIZED ANTI-EGFL7 ANTIBODIES AND METHODS USING SAME - The present invention concerns antibodies to EGFL7 and the uses of same. | 2014-02-20 |
20140051121 | FEED MIXING DEVICE AND ITS USE - Herein is reported a feed mixing device for adding feed solutions with a non-physiologically pH value to a cell cultivation vessel comprising a chamber for mixing the feed solutions prior to their addition to the cell cultivation vessel as well as its use. With the feed mixing device as reported herein feed components can be provided in solution at a pH value at which they have good solubility and/or good stability whereby the pH value can be clearly different from the pH value of the cultivation medium, i.e. different from the physiological pH value. This allows performing the cultivation with more flexibility compared to a cultivation in which the pH value of the feed solution is limited to a small range around the pH value of the cultivation. | 2014-02-20 |
20140051122 | LARGE SCALE AND STABLE PRODUCTION OF HUMAN FVIII IN THE HUMAN CELL LINE SK-HEP-1 - The present invention refers to: 1) the method for the production of recombinant FVIII in human Sk-Hep-1 cells, comprising von Willebrand Factor (vWF) and 2) the population of human cells transduced with a vector encoding the clotting protein (FVIII). The technical object of the present patent application is intended for the cultivation of human cells in suspension and in adhesion and isolation of the culture medium containing the desired protein. | 2014-02-20 |
20140051123 | METHOD OF INCREASING THE PRODUCTIVITY OF EUCARYOTIC CELLS IN THE PRODUCTION OF RECOMBINANT FVIII - A method of increasing productivity, in particularly cell-specific productivity, of recombinant factor VIII (rFVIII) produced in a eukaryotic cell suspension during culturing of the eucaryotic cell suspension in a culturing medium containing not more than 500 μM CaCl | 2014-02-20 |
20140051124 | METHODS FOR REDUCING ACCUMULATION OF LACTATE DURING CULTURING AND METHOD FOR PRODUCING POLYPEPTIDE - The present disclosure relates to methods of decreasing lactate production in cell culture using divalent transitional metallic salts. The present disclosure also relates to a method of producing polypeptide by adding divalent transitional metallic salt to the cell culture medium for reducing lactate accumulation followed by fermenting and recovering the polypeptide. | 2014-02-20 |
20140051125 | Stable Production of Lentiviral Vectors - The present invention provides new stable packaging cell lines and producer cell lines as well as methods to obtain them, and a new method to produce lentiviral vectors using such cell lines. New methods and packaging cell lines of the invention are generated using a baculo-AAV hybrid system for stable expression of structural and regulatory lentiviral proteins, such system comprising a baculoviral backbone containing an integration cassette flanked by AAV ITR, in combination with a plasmid encoding rep protein. This system allows to obtain a stable integration of the structural and regulatory HIV-1 proteins gag/pol and rev. The system allows to obtain a first intermediate including only the structural and regulatory HIV proteins gag/pol and rev, to be used as starting point to obtain stable packaging cell lines as well as producer cell lines. | 2014-02-20 |
20140051126 | DNA POLYMERASES WITH IMPROVED ACTIVITY - Disclosed are DNA polymerases having increased reverse transcriptase efficiency relative to a corresponding, unmodified polymerase. The polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the DNA polymerases. | 2014-02-20 |
20140051127 | LARGE SCALE ENZYMATIC SYNTHESIS OF OLIGOSACCHARIDES - A novel UDP-Gal regeneration process and its combined use with a galactosyltransferase to add galactose to a suitable acceptor substrate. Also described herein are synthetic methods for generating Globo-series oligosaccharides in large scale, wherein the methods may involve the combination of a glycosyltransferase reaction and a nucleotide sugar regeneration process. | 2014-02-20 |
20140051128 | Endoglucanases for Treatment of Cellulosic Material - The present invention relates to production of fermentable sugars from lignocellulosic material by enzymatic conversion. The fermentable sugars are useful e.g. in the production of bioethanol. Novel polypeptides having endoglucanase activity, polynucleotides encoding them and vectors and host cells containing the polynucleotides are disclosed. A method for treating cellulosic material with the novel endoglucanase as well as uses of the enzymes and enzyme preparations and a method of preparing them are described. | 2014-02-20 |
20140051129 | POTENTIATION OF ENZYMATIC SACCHARIFICATION - The present disclosure provides methods of potentiating the activity of an enzyme cocktail by the addition of one or more enzymes. In some embodiments, a sub-maximum or sub-optimal dose of the cocktail may be used in combination with the enzymes. In some embodiments, the enzyme or enzymes are expressed in planta. | 2014-02-20 |
20140051130 | Compositions for saccharification of cellulosic material - The present invention relates to enzyme compositions for high temperature saccharification of cellulosic material and to uses thereof. | 2014-02-20 |
20140051131 | Process for Production of Microalgae, Cyanobacteria and Metabolites Thereof - The present invention relates to processes for the production of microalgae, cyanobacteria and/or metabolites thereof. Described herein is a process involving, the use of a stimulus applied to a microalgal or cyanobacterial culture to enhance the production of one or more metabolites. Also described herein, is a process for the production of microalgae and/or cyanobacteria comprising an adaptation stage wherein an algaltcyanobacterial culture is grown on a process water feedstock and/or under light emitting diodes (LEDs) emitting light within the spectrum of light wavelengths between around 400 nm and 700 nm, and a production phase, wherein the microalgae or cyanobacteria are grown on the same process water feedstock and/or under the same light conditions used in the adaptation stage. The invention also relates to specific microalgal strains. | 2014-02-20 |
20140051132 | Method for Producing an L-Amino Acid Belonging to the Glutamate Family, Using a Coryneform Bacterium - The present invention provides a method for producing an L-amino acid belonging to the glutamate family, using a coryneform bacterium which has been modified so that expression of one or more gene(s) of the NCgl_2067-NCgl_2065 operon in said bacterium is/are attenuated. | 2014-02-20 |
20140051133 | KETOL-ACID REDUCTOISOMERASE ENZYMES AND METHODS OF USE - Provided herein are polypeptides having ketol-aid reductoisomerase activity as well as microbial host cells comprising such polypeptides. Polypeptides provided herein may be used in biosynthetic pathways, including, but not limited to, isobutanol biosynthetic pathways. | 2014-02-20 |
20140051134 | METHOD FOR PRODUCING PHOSPHITE DEHYDROGENASE PROTEIN AND USE THEREOF - In order to provide: a phosphite dehydrogenase protein having both improved solubility and improved heat stability; a method for producing a gene encoding the phosphite dehydrogenase protein; a method for producing the phosphite dehydrogenase protein; and use of the phosphite dehydrogenase protein, (i) a phosphite dehydrogenase protein having a specific amino acid sequence and (ii) a gene encoding the phosphite dehydrogenase protein are used. | 2014-02-20 |
20140051135 | PLANT CELL CULTURE FOR PRODUCTION OF NATURAL PRODUCTS WITH REDUCED GLUCOSINOLATE CONTAMINATION - Disclosed are methods for obtaining a natural product preparation with reduced glucosinolate contamination from a plant of Brassicaceae. The methods can include cultivating a plant callus from a plant capable of producing a desired natural product, selecting a callus with reduced glucosinolate production, and cultivating the selected callus in a liquid medium. The method can also include recovering the natural product from the culture. Also disclosed are methods for obtaining cabbage anthocyanin with reduced glucosinolate contamination. The methods can include cultivating a red cabbage plant callus with reduced glucosinolate production in a liquid medium to obtain a suspension culture and cultivating the suspension culture in a medium lacking a nitrogen source. The method can also include recovering the anthocyanin with reduced glucosinolate contamination from the culture. Finally, several specific low-glucosinolate cell lines are described. | 2014-02-20 |
20140051136 | Micoorganisms and Methods for the Production of Fatty Acids and Fatty Acid Derived Products - This invention relates to metabolically engineered microorganism strains, such as bacterial strains, in which there is an increased utilization of malonyl-CoA for production of a fatty acid or fatty acid derived product, wherein the modified microorganism produces fatty acyl-CoA intermediates via a malonyl-CoA dependent but malonyl-ACP independent mechanism | 2014-02-20 |
20140051137 | IDENTIFICATION AND USE OF BACTERIAL [2Fe-2S] DIHYDROXY-ACID DEHYDRATASES - A group of bacterial dihydroxy-acid dehydratases having a [2Fe-2S] cluster was discovered. Bacterial [2Fe-2S] DHADs were expressed as heterologous proteins in bacteria and yeast cells, providing DHAD activity for conversion of 2,3-dihydroxyisovalerate to α-ketoisovalerate or 2,3-dihydroxymethylvalerate to α-ketomethylvalerate. Isobutanol and other compounds may be synthesized in pathways that include bacterial [2Fe-2S] DHAD activity. | 2014-02-20 |
20140051138 | MUTANT STRAIN OF LACTIC ACID PRODUCING YEAST AND PROCESS FOR PRODUCING LACTIC ACID - A lactic acid-producing yeast mutant which is a mutant of a yeast prepared by introduction of a lactate dehydrogenase gene that results in lactic acid-producing ability, the mutant having, in a medium at pH 3, a lactic acid-producing ability equivalent to or higher than the lactic acid-producing ability of a parent strain of the mutant at a lactic acid fermentation optimum pH. | 2014-02-20 |
20140051139 | PROCESSES FOR BIOCONVERSION OF SYNGAS TO OXYGENATED ORGANIC COMPOUND PROVIDING STORAGE AND REACTIVATION OF MICROORGANISM CONCENTRATES - Processes are disclosed for preparing microorganism concentrates from fermentation broth containing a free suspension of the microorganisms which is used for the anaerobic conversion of syngas to oxygenated organic compound. The processes involve the use of processing steps and the presence of certain additives to enhance the ability of the microorganism concentrate to be stored for extended periods and reactivated. | 2014-02-20 |
20140051140 | PROCESS OF BIOLOGICALLY PRODUCING A p-HYDROXYBENZOIC ACID - A method of biologically producing p-hydroxybenzoic acid, and a method for producing p-hydroxybenzoic acid from lignin through chemical and biological conversion. | 2014-02-20 |
20140051141 | METHOD FOR INCREASING ALCOHOL YIELD FROM GRAIN - A process for increasing alcohol yield from grain that includes adding cellulase enzymes or a mixture of cellulase enzymes to break down cellulostic feedstock, which is typically discarded. The cellulase enzymes or a mixture of cellulase enzymes may be added to a conventional alcohol production process either through a joint or separate fermentation process. | 2014-02-20 |
20140051142 | Polypeptides Having Cellobiohydrolase I Activity and Polynucleotides Encoding Same - The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides. | 2014-02-20 |
20140051143 | Polypeptides Having Cellobiohydrolase I Activity and Polynucleotides Encoding Same - The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides. | 2014-02-20 |
20140051144 | SILICA ENCAPSULATED BIOMATERIALS - The present invention relates to compositions for encapsulation of biomaterials in a silica-matrix. The present invention includes a composition for formation of a silica-matrix encapsulated biomaterial. The composition includes a reactive silicon compound and a biomaterial with a catalytic activity. When encapsulated in the silica-matrix, the biomaterial at least partially retains its catalytic activity. The present invention also relates to methods of making silica-matrix encapsulated biomaterials, and to methods of using silica-matrix encapsulated biomaterials, including methods of treating water or gas using the silica-matrix encapsulated biomaterials. | 2014-02-20 |
20140051145 | NUCLEIC ACID AND CORRESPONDING PROTEIN NAMED 158P1D7 USEFUL IN THE TREATMENT AND DETECTION OF BLADDER AND OTHER CANCERS - The invention described herein relates to novel nucleic acid sequences and their encoded proteins, referred to as 158P1D7 and variants thereof, and to diagnostic and therapeutic methods and compositions useful in the management of various cancers that express 158P1D7 and variants thereof. | 2014-02-20 |
20140051146 | METHOD - In one aspect there is provided a method for producing a recombinant enzyme capable of hydrolysing chlorophyll or a chlorophyll derivative, comprising a step of intracellular expression of the recombinant enzyme in a eukaryotic host cell. | 2014-02-20 |
20140051147 | SURFACTANT TOLERANT CELLULASE AND METHOD FOR MODIFICATION THEREOF - A method for suppressing a reduction in an endoglucanase activity in the presence of a surfactant, characterized by modifying a protein having the endoglucanase activity in which the N-terminus is an amino acid other than pyroglutamic acid, to a protein having the N-terminus of pyroglutamic acid, is disclosed. Further, a modified protein having an endoglucanase activity wherein the N-terminal amino acid is converted into pyroglutamic acid by an amino acid modification, a polynucleotide encoding the protein, an expression vector comprising the polynucleotide, a host cell transformed with the expression vector, and a process for producing the protein by cultivating the host cell, are disclosed. | 2014-02-20 |
20140051148 | Cells and Methodology to Generate Non-Segmented Negative-Strand RNA Viruses - The present invention relates to recombinant cells as well as to methods for the generation of non-segmented negative-sense single-stranded RNA viruses (NNV or mononegavirales) from cloned deoxyribonucleic acid (cDNA), especially from measles virus and in particular from attenuated strains such as those approved for vaccination, in particular from the attenuated Schwarz measles virus and various recombinant Schwarz measles-based viruses expressing heterologous sequences. Such rescued viruses can be used, after amplification, as vaccines for immunization against measles and/or against the heterologous peptides or proteins expressed. | 2014-02-20 |
20140051149 | MICROBIAL ENHANCED OIL RECOVERY METHODS - The present invention is directed to the field of microbial enhanced oil recovery (MEOR). In particular, the invention focuses on new, efficient, economical and environmentally safe microbial methods to enhance oil recovery in existing oil reservoirs, as well as microorganisms useful in such methods. | 2014-02-20 |
20140051150 | ISOLATION OF A PROTEIN RESPONSIBLE FOR URANIUM (VI) REDUCTION - The present invention relates to the isolation and characterization of a protein responsible for the reduction of uranium (VI) to uranium (IV). The present invention extends to the use of the isolated protein in the reduction of uranium (VI) to uranium (IV) and further extends to a process for the bioremediation, or at least partial remediation, of a site contaminated with a source of U (VI). According to a first aspect thereof, the present invention provides an isolated polypeptide derived from | 2014-02-20 |
20140051151 | Fermentive Production of Four Carbon Alcohols - Methods for the fermentative production of four carbon alcohols is provided. Specifically, butanol, preferably isobutanol is produced by the fermentative growth of a recombinant bacterium expressing an isobutanol biosynthetic pathway. | 2014-02-20 |
20140051152 | A-87774 Compounds or Salts Thereof, Production Method Thereof and Agrochemicals Containing the Same as Active Ingredient - There are provided novel A-87774 compounds or salts thereof having a herbicidal activity or a plant growth regulating activity, a microorganism producing the same, a production method thereof, an agrochemical (in particular, herbicide or plant growth regulator) containing the same as an active ingredient, a method for using the same, and a culture of the microorganism. | 2014-02-20 |
20140051153 | PROCESS FOR THE DESTRUCTION OF ORGANICS IN BAYER PROCESS STREAMS - A process for the destruction of organics in a Bayer process stream, the process comprising the steps of: a) Passing a volume of a Bayer process stream to a reactor vessel in which is provided a population of a mixed bacterial culture; and b) Retaining that volume of the Bayer process stream in the reactor vessel for a period of time during which at least 10% by mass as carbon of the organic compounds destroyed originate from non-oxalate organic compounds, wherein the mixed bacterial culture comprises a mix of bacterial species capable of destroying organics and which has previously been adapted to the Bayer process stream, or a stream of substantially similar composition, prior to introduction to the reactor vessel. | 2014-02-20 |
20140051154 | SYSTEMS AND METHODS TO DETECT COPY NUMBER VARIATION - In one aspect, a system for implementing a copy number variation analysis method, is disclosed. The system can include a nucleic acid sequencer and a computing device in communications with the nucleic acid sequencer. The nucleic acid sequencer can be configured to interrogate a sample to produce a nucleic acid sequence data file containing a plurality of nucleic acid sequence reads. In various embodiments, the computing device can be a workstation, mainframe computer, personal computer, mobile device, etc. | 2014-02-20 |
20140051155 | THERMAL CYCLER APPARATUS AND RELATED METHODS - An apparatus for thermal cycling can transfer heat uniformly and efficiently. The apparatus can be used in a method that reduces condensation on sample wells. The apparatus can also be manufactured to provide uniform configurations. For example, a sample, illustratively for polymerase chain reaction (PCR), in each sample well and the components of the embodiment of the thermal cycler apparatus shown at including a well block, a base plate, a layer of adhesive, a peltier device, another layer of adhesive and a heat sink | 2014-02-20 |
20140051156 | IMAGING APPARATUS - An imaging apparatus, comprising a holder that holds a specimen container carrying a biological specimen, an imager that images the specimen in the specimen container, a sterilizer that supplies a drug or electromagnetic waves having a sterilization effect to the holder, and a controller that performs a sterilization process of supplying the drug or the electromagnetic waves to the holder by controlling the sterilizer at least either before or after imaging the specimen by the imager. | 2014-02-20 |
20140051157 | APPARATUS AND METHOD FOR INCREASING COLLECTION EFFICIENCY IN CAPILLARY BASED FLOWCYTOMETRY - In a particle analyzing apparatus including a capillary for passing through a fluid containing particles to be analyzed, an optical system is employed to collect fluorescent light emitted from particles or substances labeled to the particles with improved collection efficiency preserving resolution of the instrument. The optical system may include a first collection lens attached to the capillary and a first reflection element arranged adjacent to the first collection lens configured to reflect fluorescent light of one or more wavelengths. The optical system may include a second collection lens attached to the capillary and a second reflection element arranged adjacent to the second collection lens configured to reflect fluorescent light of one or more wavelengths. | 2014-02-20 |
20140051158 | SLICED SPECIMEN PREPARING APPARATUS - A sliced specimen preparing apparatus prepares a sliced specimen by slicing a surface of a specimen block in which a specimen is embedded in an embedding-substance. The apparatus includes: a cutter configured to slice the surface of the specimen block; a surface exposure determination unit configured to determine whether or not the area of a specimen portion on the surface of the specimen block is sufficient for the preparation of the sliced specimen; a specimen block transporting unit configured to transport the specimen block between the surface exposure determination unit and the cutter. The surface exposure determination unit includes a humidifying unit configured to humidify the surface of the specimen block; an irradiating unit configured to irradiate the surface of the specimen block with light; an imaging unit configured to receive reflected light from the humidified surface of the specimen block which is irradiated from the irradiating unit to acquire image data; an image data processing unit configured to discriminate the specimen portion on the surface of the specimen block from the embedding-substance portion based on the image data acquired by the imaging unit; and a controller configured to control the imaging unit, the irradiating unit, and the image data processing unit, and to determine whether or not the area of the specimen portion on the surface of the specimen block, the specimen portion being acquired by the image data processing unit, is sufficient for the preparation of the sliced specimen. | 2014-02-20 |
20140051159 | Micro-Fluidic Modules on a Chip for Diagnostic Applications - A chip having a substrate for amplifying genetic material includes a substrate heater having a plurality of substrate heating resistors. The heating resistors define a first temperature zone for maintaining a first temperature, a second temperature zone for maintaining a second temperature below the first temperature, and a third temperature zone for maintaining a third temperature between the first and second temperatures, on the substrate. A flow path formed on the substrate allows conveying of reactions to the first temperature zone, the third temperature zone, and the second temperature zone so as to undergo denaturing, annealing, and extension, respectively, according to a polymerase chain reaction process, for at least one cycle. | 2014-02-20 |
20140051160 | MICRO DROPLET OPERATION DEVICE AND REACTION PROCESSING METHOD USING THE SAME - Micro droplets are accurately placed in a reaction well. The reaction well ( | 2014-02-20 |
20140051161 | Micro-Fluidic Modules on a Chip for Diagnostic Applications - A micro-fluidic device includes a plurality of heaters on a substrate for heating the substrate. The plurality of heaters define a plurality of temperature regions having distinct temperatures on the substrate. A flow feature layer is formed above the substrate to define a channel extending across the substrate through each temperature region. As fluid is repeatedly pumped within the channel, it flows from one temperature region to a next temperature region to undergo thermal cycling. | 2014-02-20 |
20140051162 | Method of Loading and Distributing Cells in a Bioreactor of a Cell Expansion System - One or more embodiments are described directed to a method and system for loading and distributing cells in a bioreactor of a cell expansion system. Accordingly, embodiments include methods and systems that may provide for adding a plurality of cells to a fluid within a bioreactor of the cell expansion system. A first percentage of the plurality of cells is avowed to settle in the bioreactor and a second percentage of the plurality of cells is allowed to settle outside of the bioreactor. The first percentage of cells is then expanded in the bioreactor. The second percentage of cells is wasted. | 2014-02-20 |
20140051163 | Synthetic Substrate for Stem Cell Culture and Methods of Use Thereof - The present disclosure provides synthetic substrates for long-term culture of stem cells; and methods of use of the synthetic substrates. | 2014-02-20 |
20140051164 | Compositions Comprising Human Embryonic Stem Cells and Their Derivatives, Methods of Use, and Methods of Preparation - The present invention relates to a pharmaceutical composition comprising of preparations of human embryonic stem (hES) cells and their derivatives and methods for their transplantation into the human body, wherein transplantation results in the clinical reversal of symptoms, cure, stabilization or arrest of degeneration of a wide variety of presently incurable and terminal medical conditions, diseases and disorders. The invention further relates to novel processes of preparing novel stem cell lines which are free of animal products, feeder cells, growth factors, leukaemia inhibitory factor, supplementary mineral combinations, amino acid supplements, vitamin supplements, fibroblast growth factor, membrane associated steel factor, soluble steel factor and conditioned media. This invention further relates to the isolation, culture, maintenance, expansion, differentiation, storage, and preservation of such stem cells. | 2014-02-20 |
20140051165 | STEM CELL PACKAGING AND SHIPPING - This invention concerns methods of packaging and shipping stem cells. Also disclosed are related package products. | 2014-02-20 |
20140051166 | Method and medicament for inhibiting the expression of a given gene - The invention relates to an isolated RNA that mediates RNA interference of an mRNA to which it corresponds and a method of mediating RNA interference of mRNA of a gene in a cell or organism using the isolated RNA. | 2014-02-20 |
20140051167 | Concentrating Components of Fluid Circulated through a Cell Growth Chamber - One or more embodiments are described directed to a method and system for concentrating components of a fluid circulated through a cell growth chamber such as a cell growth chamber. Accordingly, embodiments include methods and systems that utilize a tangential flow filter to concentrate components of a fluid that in embodiments includes expanded cells. In embodiments, a concentrated fluid component and a concentrated cell component are generated by flowing the fluid with expanded cells across a tangential flow filter. The concentrated cell component may be recirculated to the tangential flow filter to reach some desired concentration of cells. The concentrated fluid component may be collected to utilize cellular-produced constituents in the concentrated fluid component. | 2014-02-20 |
20140051168 | THREE DIMENSIONAL CELL CULTURE COMPOSITIONS AND METHODS OF USE - Described herein is a three-dimensional cell culture scaffold composition comprising an absorbent rigid (AR) component, and in some embodiments, further comprises a gel component. The absorbent rigid component preferably comprises a glass fiber material. It is a surprising finding of the present invention that an AR component having a void volume of between approximately 70% and 95% results in a three-dimensional cell culture composition that allows for robust, high-throughput screening and high-content screening accessible tissue models with preserved cell morphology, heterogeneity of cell types and cell populations, extracellular matrix constituents, functional cell-cell and cell-extracellular matrix interactions and signaling with sufficient specificities to tissue physiology and pathology. | 2014-02-20 |
20140051169 | PRODUCT OF CROSSLINKED MATERIAL AND METHOD FOR PRODUCING THE SAME - A method for producing a nanofiber-based product includes providing a carrier material solution having a carrier material, and bringing the carrier material in contact with a collector by electrospinning. The carrier material essentially consists of a polymer being—at least after having contacted the collector—embedded in a polymer, which polymer is formed by a crosslinker of the general formula (I) | 2014-02-20 |
20140051170 | Process, Vectors and Engineered Cell Lines for Enhanced Large-Scale Transfection - Processes, vectors and engineered cell lines for large-scale transfection and protein production in mammalian cells, especially Chinese Hamster Ovary (CHO) cells are described in which transfection efficiencies are realized through the use of a single vector system, the use of functional oriP sequences in all plasmids, the use of codon-optimized Epstein-Barr virus nuclear antigen-1 (EBNA1) constructs, the use of a fusion protein between a truncated Epstein-Barr virus nuclear antigen-1c (EBNA1c) protein and a herpes simplex virus protein VP16, the use of a 40 kDa fully deacetylated poly(ethylenimine) as a transfection reagent, the use of co-expression of a fibroblast growth factor (FGF) and/or the use of protein kinase B to potentiate heterologous gene expression enhancement by valproic acid (VPA). | 2014-02-20 |
20140051171 | CONVERSION OF SOMATIC CELLS TO INDUCED REPROGRAMMED NEURAL STEM CELLS (IRNSCS) - This application relates to a method for converting somatic cells to Neural Stem Cells (NSCs). Moreover this application relates to a method for converting human fibroblasts, keratinocytes or adipocytes to neural stem cells based on linked steps of genes transduction and chemically defined medium induction. | 2014-02-20 |
20140051172 | URA5 GENE AND METHODS FOR STABLE GENETIC INTEGRATION IN YEAST - A novel gene encoding | 2014-02-20 |
20140051173 | ANALYTICAL DEVICES FOR DETECTION OF LOW-QUALITY PHARMACEUTICALS - A multilayer Paper Analytical Device (PAD) is provided for detection of at least two chemical components indicative of a low quality pharmaceutical or dietary supplement product. A method for detection of at least two chemical components indicative of a low quality pharmaceutical or dietary supplement product is also provided that employs a multilayer PAD. A kit is provided for detection of at least two chemical components indicative of a low quality pharmaceutical or dietary supplement product that includes a multilayer PAD and instructions for using the kit. | 2014-02-20 |
20140051174 | NANOFLUIDIC PLATFORM FOR SINGLE MITOCHONDRIA ANALYSIS - A microfluidic device for mitochondria analysis includes an inlet coupled to a first access channel, an outlet coupled to a second access channel, and a plurality of trapping channels fluidically coupled at one end to the first access channel and fluidically coupled at an opposing end to the second access channel, each trapping channel comprises a cross-sectional dimension about 2 μm in one direction and a cross-sectional dimension between about 0.45 and about 0.75 μm in a second direction. | 2014-02-20 |
20140051175 | INSTRUMENT AND METHOD FOR ANALYSIS OF MANNOSE 6-PHOSPHATE - Disclosed are an apparatus and method for separation analysis of mannose-6-phosphate (M6P) by post-column fluorescence detection method. The apparatus is based on chromatography, and includes a column with a solid phase having affinity for phosphate, a flow path for the eluate, a heater installed on the flow path for M6P and a basic amino acid to react by heating the eluate in the flow path, and a fluorescence detector installed downstream of the heater for continuously irradiating the eluate with excitation light and measuring the intensity of the emission, and may include in the flow path a supply channel for addition of a basic amino acid between the column and the heater. The method is characterized in that it uses the apparatus and a second mobile phase consisting of a second buffer containing phosphate of predetermined concentration and adjusted to a predetermined pH. | 2014-02-20 |
20140051176 | VITAMIN D METABOLITE DETERMINATION UTILIZING MASS SPECTROMETRY FOLLOWING DERIVATIZATION - The invention relates to the detection of vitamin D metabolites. In a particular aspect, the invention relates to methods for detecting derivatized vitamin D metabolites by mass spectrometry. | 2014-02-20 |
20140051177 | FIBER OPTIC PROBE AND MEASURING SENSOR USING SAID PROBE - The fiber optic probe ( | 2014-02-20 |
20140051178 | SPECIMEN TEST UNIT - A self-contained specimen testing unit consisting of a swab-tip with attached, hollow swab-stick, an outer, elongated, removable tube housing cover that surrounds and protects the swab-tip and swab-stick, a dropper removably secured to the end of the tube cover, a dropper cap, a piercing closure member, a rotatable base closure member coupled to the piercing closure element, a membrane member mounted in the base closure member, and reagent-solution storage container screwed onto the end of the rotatable base closure member and sealed by the membrane member thereof. A method of using the unit is also disclosed whereby the piercing unit pierces the membrane when reagent solution is to be delivered to the swab-tip. | 2014-02-20 |
20140051179 | System for Visual and Electronic Reading of Colorimetric Tubes - Gas detector tubes may be used to determine a concentration of target gases in air. The gas detector tubes described may be read either by and optical reader or visually by the user. A gas detector tube reader having an optical reader capable of reading a length of stain, a color change and color density of a reagent in a gas detector tube. The gas detector tube may further comprise sensors for measuring the environmental conditions during sampling. | 2014-02-20 |
20140051180 | SYNCHRONIZATION OF ION GENERATION WITH CYCLING OF A DISCONTINUOUS ATMOSPHERIC INTERFACE - The invention generally relates to methods and devices for synchronization of ion generation with cycling of a discontinuous atmospheric interface. In certain embodiments, the invention provides a system for analyzing a sample that includes a mass spectrometry probe that generates sample ions, a discontinuous atmospheric interface, and a mass analyzer, in which the system is configured such that ion formation is synchronized with cycling of the discontinuous atmospheric interface. | 2014-02-20 |
20140051181 | Glow Discharge Ion Source - A mass spectrometer is disclosed comprising a glow discharge device within the initial vacuum chamber of the mass spectrometer. The glow discharge device may comprise a tubular electrode located within an isolation valve, which is provided in the vacuum chamber. Reagent vapour may be provided through the tubular electrode, which is then subsequently ionised by the glow discharge. The resulting reagent ions may be used for Electron Transfer Dissociation of analyte ions generated by an atmospheric pressure ion source. Other embodiments are contemplated wherein the ions generated by the glow discharge device may be used to reduce the charge state of analyte ions by Proton Transfer Reaction or may act as lock mass or reference ions. | 2014-02-20 |
20140051182 | Pipetting Apparatus, Pipetting Container and Method for the Production Thereof - The invention relates to a pipetting apparatus for pipetting laboratory samples into a pipetting container which can be connected to the pipetting apparatus, which pipetting container is in particular designed according to the invention, comprising a container side and a first connection section, by means of which the pipetting container can be connected to the pipetting apparatus, and comprising an information carrying device with at least one information section, which carries information, on this container side; the pipetting apparatus comprising an electric information reading device, by means of which information contained on the information reading device can be read when the pipetting container is connected to the pipetting apparatus, and which comprises at least one electric sensor device, which comprises at least one sensor section, opposite to which a measuring space is formed, wherein the sensor device is configured to read the information content of at least one information section when the latter is arranged in the measuring space. The invention furthermore relates to the pipetting container or adapter element, which can be used with the pipetting apparatus, and a method for the production thereof. | 2014-02-20 |
20140051183 | BIOMARKERS FOR THE PREDICTION OF INCIDENT CANCER - Subject of the present invention is a method of assessing the susceptibility of a subject to acquire cancer and/or assessing the risk of cancer mortality for a subject, who has not had clinically manifest cancer and/or does not have clinically manifest cancer at the time when applying this method. | 2014-02-20 |
20140051184 | MOBILITY SHIFT ASSAYS FOR DETECTING ANTI-TNF ALPHA DRUGS AND AUTOANTIBODIES THERETO - The present invention provides assays for detecting and measuring the presence or level anti-TNFα drugs and/or the autoantibodies to anti-TNFα drugs in a sample. The present invention is useful for optimizing therapy and monitoring patients receiving anti-TNFα drug therapeutics to detect the presence or level of autoantibodies against the drug. The present invention also provides methods for selecting therapy, optimizing therapy, and/or reducing toxicity in subjects receiving anti-TNFα drugs for the treatment of TNFα-mediated disease or disorders. | 2014-02-20 |
20140051185 | MARKERS FOR PREECLAMPSIA - This document provides methods and materials related to determining whether or not a pregnant mammal (e.g., a pregnant human) has preeclampsia. For example, methods and materials related to the use of urinary podocytes to determine whether or not a pregnant human has preeclampsia are provided. | 2014-02-20 |
20140051186 | METHOD OF PRODUCING FUNCTIONAL MOLECULE-CONTAINING SILICA NANOPARTICLES ON WHICH BIOMOLECULES ARE BONDED - A method of producing functional molecule-containing silica nanoparticles on which a biomolecule is bonded, containing the steps of:
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20140051187 | EVALUATING ASSAYS WHICH OPTICAL INHOMOGENEITIES - The invention relates to a method and a sensor device (100) for evaluating an assay with a sample. During the assay, optical measurements are made at a sensing surface (112), and at least one “homogeneity-image” of the sensing surface (112) is generated. From this image, an “homogeneity-indicator” is determined for at least one region of interest, and the optical measurements are then evaluated in dependence on said indicator. The homogeneity-indicator may for example be a binary value which indicates if an inhomogeneity was detected or not. If an inhomogeneity was detected, all optical measurements may be rejected, only measurements for the involved region of interest may be rejected, or measurements for a selected sub-area of the involved region of interest(ROI) may be rejected. | 2014-02-20 |
20140051188 | METHOD FOR OBTAINING BINDING KINETIC RATE CONSTANTS USING FIBER OPTIC PARTICLE PLASMON RESONANCE (FOPPR) SENSOR - A method for obtaining the binding kinetic rate constants using fiber optic particle plasmon resonance (FOPPR) sensor, suitable for a test solution with two or more concentrations, which employs the following major steps: providing one FOPPR sensor instrument system, obtaining optical time-resolved signal intensities starting at the initial time to the steady state of the two or more regions, substituting the measured signal intensity values into the formula which is derived by using the pseudo-first order rate equation model. In addition, this method measures the temporal signal intensity evolution under static conditions as the samples are quickly loaded. As a result, unlike the conventional device where the sample is continuously infused, the method is able to measure the association and dissociation rate constants of which the upper bounds are not limited by the sample flow rate. | 2014-02-20 |
20140051189 | METHOD FOR WAFER-LEVEL TESTING DICED MULTI-CHIP STACKED PACKAGES - Disclosed is a method for wafer-level testing a plurality of diced multi-chip stacked packages. Each package includes a plurality of chips with vertically electrical connections such as TSVs. Next, according to a die-on-wafer array arrangement, the multi-chip stacked packages are fixed on a transparent reconstructed wafer by a photo-sensitive adhesive, and the packages are located within the component-bonding area of the wafer. Then, the transparent reconstructed wafer carrying the multi-chip stacked packages can be loaded into a wafer tester for probing. Accordingly, the wafer testing probers in the wafer tester can be utilized to probe the testing electrodes of the stacked packages so that it is easy to integrate this wafer-level testing method especially into TSV packaging processes. | 2014-02-20 |
20140051190 | METHOD OF LARGE-AREA CIRCUIT LAYOUT RECOGNITION - Methods for detecting the physical layout of an integrated circuit are provided. The methods of the present disclosure allow large area imaging of the circuit layout without requiring tedious sample preparation techniques. The imaging can be performed utilizing low-energy beam techniques such as scanning electron microscopy; however, more sophisticated imaging techniques can also be employed. In the methods of the present disclosure, spalling is used to remove a portion of a semiconductor layer including at least one semiconductor device formed thereon or therein from a base substrate. In some cases, a buried insulator layer that is located beneath a semiconductor layer including the at least one semiconductor device can be completely or partially removed. In some cases, the semiconductor layer including the at least one semiconductor device can be thinned. The methods improve the detection quality that the buried insulator layer and a thick semiconductor layer can reduce. | 2014-02-20 |
20140051191 | EXTREMELY NON-DEGENERATE TWO PHOTON ABSORPTION OPTICAL SENSING METHOD, APPARATUS AND APPLICATIONS - An extremely non-degenerate two photon absorption (END-2PA) method and apparatus provide for irradiating a semiconductor material substrate simultaneously with two photons each of different energy less than a bandgap energy of the semiconductor material substrate but in an aggregate greater than the bandgap energy of the semiconductor material substrate. A ratio of a higher energy photon energy to a lower energy photon energy is at least about 3.0. Alternatively, or as an adjunct, the higher energy photon has an energy at least about 75% of the bandgap energy and the lower energy photon has an energy no greater than about 25% of the bandgap energy. | 2014-02-20 |
20140051192 | METHOD AND CARRIER SUBSTRATE FOR MANUFACTURING DISPLAY DEVICE - A method of manufacturing a display device, the method including forming a first layer on a rigid glass substrate, the first layer having a hydrophobic surface; forming a second layer to be bonded to a rigid thin glass substrate on the first layer to prepare a carrier substrate; bonding the rigid thin glass substrate onto the second layer; forming and encapsulating a display portion on an upper surface of the rigid thin glass substrate; and irradiating a laser beam to delaminate the first layer and detaching the rigid thin glass substrate from the rigid glass substrate. | 2014-02-20 |
20140051193 | LIGHT-EMITTING ELEMENT PACKAGE AND FABRICATION METHOD THEREOF - A fabrication method for a light-emitting element package, the method comprising: providing a high precision wafer level mold module, the high precision wafer level mold module comprising an upper mold and a bottom mold; mounting a substrate with a plurality of light-emitting elements between the upper mold and the bottom mold; filling package materials into the high precision wafer level mold module to obtain package members mounted on the light-emitting elements; and removing the high precision wafer level mold module. | 2014-02-20 |
20140051194 | METHOD OF PRODUCING AT LEAST ONE OPTOELECTRONIC SEMICONDUCTOR CHIP - A method of producing at least one optoelectronic semiconductor chip includes providing at least one optoelectronic structure, including a growth support and a semiconductor layer sequence with an active region, the semiconductor layer sequence being deposited epitaxially on the growth support, providing a carrier, applying the at least one optoelectronic structure onto the carrier with its side remote from the growth support, coating the at least one optoelectronic structure with a protective material, the protective material covering the outer face, remote from the carrier, of the growth support and side faces of the growth support and of the semiconductor layer sequence, and detaching the growth support from the semiconductor layer sequence of the at least one optoelectronic structure. | 2014-02-20 |
20140051195 | METHOD OF MANUFACTURING ENCAPSULATION STRUCTURE FOR ENCAPSULATING LED CHIP - A method of manufacturing an encapsulation structure for encapsulating an LED chip includes the following steps: providing a first encapsulation defining a receiving room for receiving the LED chip therein and a second encapsulation defining a receiving space for receiving the first encapsulation therein; providing a mounting tablet defining an entrance therein, mounting the first encapsulation and the second encapsulation on the mounting tablet with a clearance defined therebetween communicating with the entrance; injecting a liquid transparent resin with phosphorous compounds disturbed therein into the clearance via the entrance; and solidifying the liquid transparent resin to form a transparent resin layer interconnecting the first encapsulation and the second encapsulation. | 2014-02-20 |
20140051196 | METHOD AND APPARATUS FOR MANUFACTURING OPTICAL DEVICE - An optical device manufacturing apparatus includes an encapsulating device for encapsulating an optical semiconductor element | 2014-02-20 |
20140051197 | METHOD FOR FABRICATING A VERTICAL LIGHT EMITTING DIODE (VLED) DIE HAVING EPITAXIAL STRUCTURE WITH PROTECTIVE LAYER - A method for fabricating a vertical light emitting diode (VLED) die includes the steps of: providing a substrate; forming an epitaxial structure on the substrate; forming an electrically insulative insulation layer covering the lateral surfaces of the epitaxial structure; forming an electrically non-conductive material on the electrically insulative insulation layer; and forming a mirror on the p-doped layer, with the electrically insulative insulation layer configured to protect the epitaxial structure during formation of the mirror. | 2014-02-20 |
20140051198 | METHOD AND APPARATUS FOR MANUFACTURING ORGANIC EL DEVICE - Provided is a method for manufacturing an organic EL device, including: a vapor deposition step of forming an organic layer over a substrate moving relative to a nozzle by discharging a vaporized organic layer-forming material through the nozzle. The vapor deposition step is performed so that a light emitting region formed of the organic layer and having a width A (mm) in a direction perpendicular to a direction in which the substrate is moving is formed, and so that W≧A+2×h (where h≦5 mm) is satisfied, where a length of an opening of the nozzle in the direction perpendicular to the direction in which the substrate is moving is denoted by W (mm), and a distance between the opening and the substrate is denoted by h (mm). | 2014-02-20 |
20140051199 | METHOD FOR PRODUCING SILICON SOLOR CELLS HAVING A FRONT-SIDED TEXTURE AND A SMOOTH REAR SIDE - Method for producing a silicon solar cell which is smoothly etched on one side, in which a front side and a rear side of a silicon substrate are etched ( | 2014-02-20 |
20140051200 | METHOD FOR FABRICATING PHOTO DETECTOR - A photo detector and related fabricating method are disclosed. The photo detector includes a substrate, a first patterned semiconductor layer, a dielectric layer, a patterned conductive layer, an inter-layer dielectric, a second patterned semiconductor layer, two first electrodes disposed on the inter-layer dielectric and two second electrodes disposed on portions of the second semiconductor layer. The first patterned semiconductor layer having a first doping region and a second doping region is disposed on a transistor region. The dielectric layer is disposed to cover the substrate and the first semiconductor layer. The patterned conductive layer is disposed on the dielectric layer. The inter-layer dielectric having at least two openings adapted to expose the first doping region and the second doping region is disposed to cover the dielectric layer. The second patterned semiconductor layer is disposed on a photosensitive region. The first electrodes are electrically connected to the first patterned semiconductor layer. | 2014-02-20 |
20140051201 | SILICON SURFACE TEXTURING METHOD FOR REDUCING SURFACE REFLECTANCE - A method of texturing a surface of a crystalline silicon substrate is provided. The method includes immersing a crystalline silicon substrate into an aqueous alkaline etchant solution to form a pyramid shaped textured surface, with (111) faces exposed, on the crystalline silicon substrate. The aqueous alkaline etchant solution employed in the method of the present disclosure includes an alkaline component and a nanoparticle slurry component. Specifically, the aqueous alkaline etchant solution of the present disclosure includes 0.5 weight percent to 5 weight percent of an alkaline component and from 0.1 weight percent to 5 weight percent of a nanoparticle slurry on a dry basis. | 2014-02-20 |
20140051202 | METHOD OF FABRICATING SOLAR CELL - A method of fabricating a solar cell includes the following steps. At first, a substrate including a doped layer is provided. Subsequently, a patterned material layer partially overlapping the doped layer is formed on the substrate, and a first metal layer is conformally formed on the patterned material layer and the doped layer. Furthermore, a patterned mask layer totally overlapping the patterned material layer is formed on the first metal layer, and a second metal layer is formed on the doped layer not overlapped by the patterned material layer. Then, the patterned mask layer, the first metal layer between the patterned mask layer and the patterned material layer and a part of the patterned material layer are removed. | 2014-02-20 |
20140051203 | MANUFACTURING METHOD OF SOLID-STATE IMAGE SENSOR - A single crystal silicon layer is formed on a principal surface of a first wafer by epitaxial growth. A silicon oxide layer is formed on the single crystal silicon layer. Next, a defect layer is formed inside the single crystal silicon layer by ion implantation, and then, the second wafer is bonded to the silicon oxide layer on the first wafer. After that, an SOI wafer including the silicon oxide layer formed on the second wafer and the single crystal silicon layer formed on the silicon oxide layer is formed by separating the first wafer including the single crystal silicon layer from the second wafer including the single crystal silicon layer in the defect layer. Then, a photodiode is formed in the single crystal silicon layer. An interconnect layer is formed on a surface of the single crystal silicon layer which is opposite to the silicon oxide layer. | 2014-02-20 |
20140051204 | SOLID-STATE IMAGING DEVICE, METHOD OF MANUFACTURING THE SAME, AND IMAGING APPARATUS - A solid-state imaging device includes a photoelectric conversion section which is disposed on a semiconductor substrate and which photoelectrically converts incident light into signal charges, a pixel transistor section which is disposed on the semiconductor substrate and which converts signal charges read out from the photoelectric conversion section into a voltage, and an element isolation region which is disposed on the semiconductor substrate and which isolates the photoelectric conversion section from an active region in which the pixel transistor section is disposed. The pixel transistor section includes a plurality of transistors. Among the plurality of transistors, in at least one transistor in which the gate width direction of its gate electrode is oriented toward the photoelectric conversion section, at least a photoelectric conversion section side portion of the gate electrode is disposed within and on the active region with a gate insulating film therebetween. | 2014-02-20 |
20140051205 | METHOD FOR MANUFACTURING THIN FILM COMPOUND SOLAR CELL - To manufacture a thin film compound solar cell which can improve the adhesive property of electrodes even when being provided with a base material, and which prevents the base material from being separated. A cell main body configured by laminating a plurality of compound semiconductor layers is formed on a substrate. A rear surface electrode | 2014-02-20 |
20140051206 | METHOD AND APPARATUS PROVIDING MULTI-STEP DEPOSITION OF THIN FILM LAYER - A multi-stage method and apparatus for vaporizing and depositing a tellurium containing semiconductor material on a substrate. | 2014-02-20 |
20140051207 | SUBSTRATE FOR ORGANIC ELECTRONIC DEVICE - The present invention relates to a substrate for an organic electrode device, a manufacturing method thereof, and an organic electronic device. An exemplary substrate of the invention, if an organic light emitting element is formed on an upper part of the substrate, can obtain luminance with high emission and uniformity by efficiently controlling the surface resistance of an electrode even when the device is configured into larger sizes. | 2014-02-20 |
20140051208 | Memory Cells and Methods of Forming Memory Cells - Some embodiments include memory cells which contain, in order; a first electrode material, a first metal oxide material, a second metal oxide material, and a second electrode material. The first metal oxide material has at least two regions which differ in oxygen concentration relative to one another. One of the regions is a first region and another is a second region. The first region is closer to the first electrode material than the second region, and has a greater oxygen concentration than the second region. The second metal oxide material includes a different metal than the first metal oxide material. Some embodiments include methods of forming memory cells in which oxygen is substantially irreversibly transferred from a region of a metal oxide material to an oxygen-sink material. The oxygen transfer creates a difference in oxygen concentration within one region of the metal oxide material relative to another. | 2014-02-20 |
20140051209 | METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE - Described is a method for manufacturing a semiconductor device. A mask is formed over an insulating film and the mask is reduced in size. An insulating film having a projection is formed using the mask reduced in size, and a transistor whose channel length is reduced is formed using the insulating film having a projection. Further, in manufacturing the transistor, a planarization process is performed on a surface of a gate insulating film which overlaps with a top surface of a fine projection. Thus, the transistor can operate at high speed and the reliability can be improved. In addition, the insulating film is processed into a shape having a projection, whereby a source electrode and a drain electrode can be formed in a self-aligned manner. | 2014-02-20 |
20140051210 | Nonvolatile Memory Elements - Nonvolatile memory elements that are based on resistive switching memory element layers are provided. A nonvolatile memory element may have a resistive switching metal oxide layer. The resistive switching metal oxide layer may have one or more layers of oxide. A resistive switching metal oxide may be doped with a dopant that increases its melting temperature and enhances its thermal stability. Layers may be formed to enhance the thermal stability of the nonvolatile memory element. An electrode for a nonvolatile memory element may contain a conductive layer and a buffer layer. | 2014-02-20 |
20140051211 | MULTICHIP ELECTRONIC PACKAGES AND METHODS OF MANUFACTURE - A multi-chip electronic package and methods of manufacture are provided. The multi-chip package includes a plurality of chips mounted on a chip carrier. The multi-chip package further includes a lid mounted on the chip carrier using a bonding material or compression seal, and at least one single piston extending from the lid. Each piston covers an entirety of multiple chips of the plurality of chips. | 2014-02-20 |
20140051212 | METHOD OF FABRICATING A PACKAGE SUBSTRATE - A method of fabricating a package substrate, includes forming a cavity in at least one region of an upper surface of a wafer, the cavity including a chip mounting region, forming a through-hole penetrating through the wafer and a via filling the through-hole, forming a first wiring layer and a second wiring layer spaced apart from the first wiring layer, which are extended into the cavity, and mounting a chip in the cavity to be connected to the first wiring layer and the second wiring layer. | 2014-02-20 |
20140051213 | Techniques for Metal Gate Work Function Engineering to Enable Multiple Threshold Voltage Nanowire FET Devices - A method of fabricating a nanowire FET device includes the following steps. A SOI wafer is provided having a SOI layer over a BOX. Nanowires and pads are etched in the SOI layer. The nanowires are suspended over the BOX. An interfacial oxide is formed surrounding each of the nanowires. A conformal gate dielectric is deposited on the interfacial oxide. A conformal first gate material is deposited on the conformal gate dielectric. A work function setting material is deposited on the conformal first gate material. A second gate material is deposited on the work function setting material to form at least one gate stack over the nanowires. A volume of the conformal first gate material and/or a volume of the work function setting material in the gate stack are/is proportional to a pitch of the nanowires. | 2014-02-20 |
20140051214 | Floating Body Field-Effect Transistors, and Methods of Forming Floating Body Field-Effect Transistors - In one embodiment, a floating body field-effect transistor includes a pair of source/drain regions having a floating body channel region received therebetween. The source/drain regions and the floating body channel region are received over an insulator. A gate electrode is proximate the floating body channel region. A gate dielectric is received between the gate electrode and the floating body channel region. The floating body channel region has a semiconductor Si | 2014-02-20 |
20140051215 | METHOD FOR MAKING THIN FILM TRANSISTOR - A method for making a thin film transistor, the method comprising: applying a gate electrode on an insulating substrate; covering the gate electrode with an insulating layer; forming a carbon nanotube layer on a growing substrate, wherein the carbon nanotube layer comprises a plurality of carbon nanotubes; transfer printing the carbon nanotube layer from the growing substrate onto the insulating layer, wherein the insulating layer insulates the carbon nanotube layer from the gate electrode; and placing a source electrode and a drain electrode spaced from each other and electrically connected to two opposite ends of at least one of the plurality of carbon nanotubes. | 2014-02-20 |
20140051216 | Replacement Gate ETSOI With Sharp Junction - A method includes providing a silicon-on-insulator wafer (e.g., an ETSOI wafer); forming a sacrificial gate structure that overlies a sacrificial insulator layer; forming raised source/drains adjacent to the sacrificial gate structure; depositing an oxide layer that covers the raised source/drains and that surrounds the sacrificial gate structure; and removing the sacrificial gate structure leaving an opening that extends to the sacrificial insulator layer. The method further includes widening the opening so as to expose some of the raised source/drains, removing the sacrificial insulator layer and forming a spacer layer on sidewalls of the opening, the spacer layer covering only an upper portion of the exposed raised source/drains, and depositing a layer of gate dielectric material within the opening. A gate conductor is deposited within the opening. | 2014-02-20 |
20140051217 | GRAPHENE NANORIBBONS AND CARBON NANOTUBES FABRICATED FROM SiC FINS OR NANOWIRE TEMPLATES - Semiconductor structures including parallel graphene nanoribbons or carbon nanotubes oriented along crystallographic directions are provided from a template of silicon carbide (SiC) fins or nanowires. The SiC fins or nanowires are first provided and then graphene nanoribbons or carbon nanotubes are formed on the exposed surfaces of the fin or the nanowires by annealing. In embodiments in which closed carbon nanotubes are formed, the nanowires are suspended prior to annealing. The location, orientation and chirality of the graphene nanoribbons and the carbon nanotubes that are provided are determined by the corresponding silicon carbide fins and nanowires from which they are formed. | 2014-02-20 |
20140051218 | THIN FILM SEMICONDUCTOR DEVICE COMPRISING A POLYCRYSTALLINE SEMICONDUCTOR LAYER FORMED ON AN INSULATION LAYER HAVING DIFFERENT THICKNESS - In an organic light emitting diode (OLED) display and a manufacturing method thereof, the OLED display includes a substrate main body; an insulation layer pattern formed on the substrate main body, and including a first thickness layer and a second thickness layer thinner than the first thickness layer; a metal catalyst that is scattered on the first thickness layer of the insulation layer pattern; and a polycrystalline semiconductor layer formed on the insulation layer pattern, and divided into a first crystal area corresponding to the first thickness layer and to a portion of the second thickness layer adjacent to the first thickness layer and a second crystal area corresponding to the remaining part of the second thickness layer. The first crystal area of the polycrystalline semiconductor layer is crystallized through the metal catalyst, and the second crystal area of the polycrystalline semiconductor layer is solid phase crystallized. | 2014-02-20 |