06th week of 2014 patent applcation highlights part 48 |
Patent application number | Title | Published |
20140038097 | TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT - A toner for electrostatic latent image development, containing toner particles composed of toner core particle containing at least a binder resin and a shell layer coating the toner core particle. Average circularities D | 2014-02-06 |
20140038098 | METHOD OF PRODUCING MAGNETIC CARRIER AND MAGNETIC CARRIER THAT USES THIS PRODUCTION METHOD - A method of producing a magnetic carrier, having a coating process step in which a surface of a magnetic carrier core is coated with particles of a resin composition by a mechanical impact force. The coating process step has a first coating process step of mixing, dispersing, and fixing the particles on the surface of the core, and a second coating process step, which is performed after the first coating process step, of carrying out a film-forming coating process on the particles. In the first and second coating process steps, the peripheral velocity of the outermost end of stirring members, the coating process time, the product temperature at the end of the coating process, and the glass-transition temperature of the resin component satisfy specific relationships. | 2014-02-06 |
20140038099 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE,AND ELECTROPHOTOGRAPHIC APPARATUS - An electrophotographic photosensitive member having excellent cleaning performance, a process cartridge, and an electrophotographic apparatus. | 2014-02-06 |
20140038100 | PARTICULATE MATERIAL PRODUCTION APPARATUS, AND PARTICULATE MATERIAL PRODUCTION METHOD - A particulate material production apparatus is disclosed. The particulate material production apparatus includes a droplet ejector to eject droplets of a particulate material composition liquid or a melted particulate material composition in a droplet ejection direction from nozzles; a solidifying device to solidify the droplets; a first airflow forming device to form a first airflow to feed the ejected droplets to the solidifying device with the first airflow; and a second airflow forming device to form a second airflow to apply the second airflow the droplets before the droplets are fed by the first airflow. The second airflow forming device forms the second airflow by supplying a pressed gas from a slit, and the traveling direction of the first airflow is substantially perpendicular to the droplet ejection direction. | 2014-02-06 |
20140038101 | Stable Emissive Toner Composition System and Method - A method of producing an emissive toner composition including selecting a photoluminescent agent, a charge control agent, and one or more additives and combining the photoluminescent agent, charge control agent, and one or more additives to form an emissive toner composition that when printed to produce an image component on a substrate, the emission spectra of the image component for irradiation with a first excitation energy includes only dominant emission peaks corresponding to one or more dominant emission peaks of the photoluminescent agent. The photoluminescent agent is selected such that it emits light having one or more dominant emission peaks in a first emission spectral region when irradiated with the first excitation energy. The charge control agent and one or more additives are selected such that they do not emit light in the visible spectrum when irradiated with visible light and does not emit light in the first emission spectral region when irradiated with the first excitation energy. | 2014-02-06 |
20140038102 | PHOTORESIST COMPOSITIONS AND METHODS OF FORMING PHOTOLITHOGRAPHIC PATTERNS - Provided are photoresist compositions useful in forming photolithographic patterns by a negative tone development process. Also provided are methods of forming photolithographic patterns by a negative tone development process and substrates coated with the photoresist compositions. The photoresist compositions include one or more polymer additive that contains a basic moiety and which is substantially non-miscible with a resin component of the resist. The compositions, methods and coated substrates find particular applicability in the manufacture of semiconductor devices. | 2014-02-06 |
20140038103 | LITHOGRAPHY USING PHOTORESIST WITH PHOTOINITIATOR AND PHOTOINHIBITOR - Technologies are generally described for a photoresist and methods and systems effective to form a pattern in a photoresist on a substrate. In some examples, the photoresist includes a resin, a photoinitiator and a photoinhibitor. The photoinitiator may be effective to generate a first reactant upon the absorption of at least one photon of a particular wavelength of light. The first reactant may be effective to render the resin soluble or insoluble in a photoresist developer. The photoinhibitor may be effective to generate a second reactant upon the absorption of at least one photon of the particular wavelength of light. The second reactant may be effective to inhibit the first reactant. | 2014-02-06 |
20140038104 | WATER-DISPERSIBLE ELECTRICALLY CONDUCTIVE FLUORINE-CONTAINING POLYANILINE COMPOSITIONS FOR LITHOGRAPHY - A water dispersible composition comprises a polyaniline copolymer having a weight average molecular weight of at least 30,000 and a polymeric acid comprising sulfonic acid groups. The polyaniline copolymer comprises i) about 10 mol % to about 15 mol % of a fluorine-containing first aniline repeat unit based on total moles of repeat units in the polyaniline copolymer, and ii) a second aniline repeat unit comprising no fluorine. The sulfonic acid groups of the polymeric acid are present in a molar amount greater than or equal to total moles of repeat units of the polyaniline copolymer. The composition has a conductivity of at least 0.0001 S/cm. | 2014-02-06 |
20140038105 | RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN - A resin comprises a structural unit derived from a compound represented by the formula (I); | 2014-02-06 |
20140038106 | N-ACYL-B-LACTAM DERIVATIVE, MACROMOLECULAR COMPOUND, AND PHOTORESIST COMPOSITION - Provided are N-acyl-β-lactam derivatives represented by the following general formula, from which a photoresist composition capable of controlling an acid diffusion length to be short is obtained; a polymer obtained by polymerizing the N-acyl-β-lactam derivative represented by the following general formula as one of starting materials; and a photoresist composition containing the polymer, | 2014-02-06 |
20140038107 | Method and System for E-Beam Lithography with Multi-Exposure - The present disclosure provides a method for electron-beam (e-beam) lithography patterning. The method includes forming a resist layer on a substrate; performing a first e-beam exposure process to the resist layer according to a first pattern; performing a second e-beam exposure process to the resist layer according to a second pattern, wherein the second patterned is overlapped to the first pattern on the resist layer; and developing the resist layer. | 2014-02-06 |
20140038108 | Light Emitting Diode Apparatus for Curing an Emulsion - An apparatus and method for curing a photo activated emulsion. The apparatus is a light emitting apparatus is a plurality of light emitting diodes (LED's) attached to a circuit board. The LED's are used to quickly and efficiently cure a photo sensitive emulsion on a mesh screen for use in silk screening. | 2014-02-06 |
20140038109 | ANTIREFLECTIVE COATING COMPOSITION AND PROCESS THEREOF - The invention relates to an antireflective coating composition comprising a crosslinkable polymer, where the crosslinkable polymer comprises at least one unit of fused aromatic moiety, at least one unit with a phenylene moiety in the backbone of the polymer, and at least one hydroxybiphenyl unit, furthermore where the polymer comprises a crosslinking moiety of structure (4), | 2014-02-06 |
20140038110 | IMAGING OPTICAL UNIT FOR A PROJECTION EXPOSURE APPARATUS - An imaging optical unit for a projection exposure apparatus serves for imaging an object field in an object plane into an image field in an image plane. The image field is arranged at a field distance from the object plane. The optical unit has a plurality of mirrors. The imaging optical unit has a wavefront aberration over the image field of a maximum of 0.3 nm and an image-side numerical aperture of at least 0.5. The image field in at least one dimension has an extent of at least 10 mm. The result is an imaging optical unit in particular suited as part of an optical system for a projection exposure apparatus for projection lithography. | 2014-02-06 |
20140038111 | PROCESSED SUBSTRATE AND METHOD FOR MANUFACTURING SAME - A processed substrate having a through-hole whose openings in respective surfaces of the processed substrate are matched to each other in size, and a method for easily manufacturing the processed substrate with high efficiency. The processed substrate ( | 2014-02-06 |
20140038112 | AQUEOUS BASE-DEVELOPABLE NEGATIVE-TONE FILMS BASED ON FUNCTIONALIZED NORBORNENE POLYMERS - Embodiments in accordance with the present invention encompass negative-tone, aqueous base developable, self-imagable polymer compositions useful for forming films that can be patterned to create structures for microelectronic devices, microelectronic packaging, microelectromechanical systems, optoelectronic devices and displays. | 2014-02-06 |
20140038113 | ACOUSTIC CONTROL OF AN ELECTRODYNAMIC COMBUSTION SYSTEM - A system is configured to apply a voltage, charge, and/or an electric field to a combustion reaction responsive to acoustic feedback from the combustion reaction. | 2014-02-06 |
20140038114 | RADIALLY FIRING IGNITER - The invention pertains to ignition systems and more particularly to spark igniters for burners and burner pilots. A spark igniter is provide, which is configured so that the spark gap is on the outer side surface of the spark igniter. | 2014-02-06 |
20140038115 | Dense/Dilute Pulverized Coal Separator Structure of Single-fireball Octagonal Direct-flow Burner - The invention discloses a dense/dilute pulverized coal separator structure of a single-fireball octagonal direct-flow burner, of which a boiler body is provided with eight burner groups, each water cooled wall is provided with two burner groups respectively, each of the burner groups comprises multiple nozzles toward the same burner, and center lines of all nozzles on the eight burner groups form an imaginary tangent circle in a furnace along the same tangential direction. In the dense/dilute pulverized coal separator structure, eight burner groups are arranged on four water cooled walls of the boiler, thus increasing pulverized coal concentration of a pulverized rich coal area, allowing wall heat load qHr of a lower burner area to be higher, allowing burning temperature of the area to meet requirements for anthracite burning stability, shortening distance of jet flow from a nozzle outlet to downstream adjacent air flow, being capable of using lower primary pulverized coal air flow velocity, enhancing heat flow intensity at the nozzle outlet, improving convection and radiation heat transfer capacity, and ensuring timely ignition of pulverized anthracite air flow and stable burning of the boiler at low load without oil. | 2014-02-06 |
20140038116 | BURNER AND A FURNACE COMPRISING SUCH A BURNER - Burner for a furnace comprising at least one supply channel for supplying an oxidizing medium and a plurality of peripheral fuel supply channels, wherein the channels have exit openings arranged adjacent each other at a burner end surface for forming during use upon reaction of supplied fuel with supplied oxidizing medium a flame front, wherein the exit openings are asymmetrically arranged with respect to any plane arranged transverse to the end surface of the burner and extending through a burner central axis whereby the distribution of the fuel exit openings and/or the dimension of the fuel exit openings and/or the exit angle of the fuel exit openings and/or the shape of the fuel exit openings are arranged asymmetrically to said any plane, such that during use a flame front is created that is asymmetrical with respect to said any plane. | 2014-02-06 |
20140038117 | IGNITION DEVICE AND METHOD - An ignition device for a combustible material can include an infrared radiation source in a housing structured to direct the infrared radiation to the combustible material. | 2014-02-06 |
20140038118 | IN-LINE ULTRAPURE HEAT EXCHANGER - A heat exchanger includes a plurality of tubes wherein at least some of the tubes are elliptical or oval in cross section and each tube includes a longitudinal axis. Each elliptical tube includes a major axis and a minor axis. The plurality of tubes is arranged in a radial pattern such that the major axes of the elliptical tubes intersect a centerline of the heat exchanger. The plurality of tubes is connected to a heater mount and a heater is also connected to the heater mount. A securing element holds the plurality of tubes, the heater and the heater mount together. A tube liner can extend along the longitudinal axis of at least one of the elliptical or oval tubes of the plurality of tubes. If a tube liner is employed, a purge fluid flow channel is defined between an outer periphery of the tube liner and an inner periphery of at least one of the elliptical or oval tubes of the plurality of tubes. | 2014-02-06 |
20140038119 | REINFORCED REFRACTORY CONTAINERS - A reinforced refractory container having a cast refractory container which includes a sidewall defining an interior volume, the sidewall having inner and outer surfaces, the container cast from a castable refractory composition, and a wound, continuous fiber tensile reinforcement structure integrated with the container sidewall. A method of fabricating the reinforced refractory container is also provided. | 2014-02-06 |
20140038120 | SELF-LIGATING ORTHODONTIC APPLIANCE AND RELATED METHODS - The appliances and methods provide a tab on a “U”-shaped clip having a labial (i.e. toward the patient's lips or cheek) section and a lingual (i.e. toward the patient's tongue) section. The tab is located in a position that facilitates access by a practitioner and also reduces the moment applied to the clip when the clips is opened and closed. Advantageously, the tab can be positioned to account for the varying degree of resistance encountered by different sections of the clip and minimize the likelihood of either distorting the clip or torquing the appliance. The tab can be positioned coplanar with the sliding mechanism. Advantageously, these appliances can provide improved ease of use, reduced clip distortion over time, and greater patient comfort. | 2014-02-06 |
20140038121 | Reduced-Friction Buccal Tube and Method of Use - An orthodontic appliance includes features for reducing friction between an interior of an archwire slot portion of the appliance and an archwire to be placed within the archwire slot. Other embodiments include a rounded exterior occlusal surface. Embodiments further include one or more receptacles for receiving an installation tool. | 2014-02-06 |
20140038122 | ORTHODONTIC CONNECTION TOOL - An orthodontic connection tool for attaching to a screw that has been embedded in a bone in the oral cavity an upper structural body to which an orthodontic tool is fixed, the orthodontic connection tool being provided with a base plate that is engageable with the screw; and a structural body fixture that is engaged with the base plate at an arbitrary position thereof and that fixes the upper structural body in a detachable manner. | 2014-02-06 |
20140038123 | DENTAL DRILL HEAD - A dental drill head, constituted of a head housing, a wind wheel, and bearings, the head housing being constituted of a head housing cover and a head housing cavity, and the wind wheel being constituted of a wind wheel shaft and wind wheel blades. An anti-suck-back device is configured between the head housing cover and a wind wheel shaft end part to which the wind wheel shaft corresponds. The present invention, which adopts the aforementioned technical scheme, firstly makes it possible to reduce the intake in of contaminants when suck-back is taking place as the impeller is braked; and secondly, while there is still a positive pressure inside the head, the rubber head covering uses elastic force to brake the impeller and completely prevents the intake of contaminants. Moreover, the structure is simple and costs are low. | 2014-02-06 |
20140038124 | DENTAL LIGHT DEVICE - A light device includes a body and a tip structure configured to be removably coupled with the housing. The tip includes a light engine that is operable for emitting light positioned at a distal end of the tip. A power supply circuit is positioned in the housing and coupled to the light engine. The power supply circuit is rechargeable and includes at least one ultracapacitor element. A non-imaging element is coupled with the light engine at the distal end. | 2014-02-06 |
20140038125 | APPARATUS AND METHOD FOR CURING MATERIALS WITH RADIATION - An instrument for curing light-curable compounds curable in the mouth of a patient, including a housing including a handle portion and a barrel portion removably secured with respect to the handle portion. A plurality of solid state, light-emitting semiconductor junction elements form an array on a substrate, and collectively emit light having wavelengths within a narrow band of wavelengths suitable for curing a compound. The array of light-emitting elements are positioned proximate to the distal end of the barrel portion, and an elongated heat-conducting element extends from the distal end of the barrel portion toward the proximal end for conducting heat away from the array. A generally clear layer extends on the substrate and over the plurality of light-emitting semiconductor junction elements, and a non-imaging optical focusing device is positioned at the distal end of the barrel portion to collimate the emitted light. | 2014-02-06 |
20140038126 | Apparatus and Method for Sinus Lift Procedure - An osteotome for sinus lift procedures includes a body interchangeable with various handles. The body includes a shaft that is releasably received into the handle, and a tip portion. The tip portion may be directly utilized for ridge expansion/bone compression, or a succession of tip members may instead be received thereon to provide suitable diameter escalation to create the socket. A conduit in the tip portion interconnects with a conduit in a hydration port and a conduit in a tip member. A hose couples the hydration port to a syringe, to deliver fluid out the tip member to lift the membrane. Graduated syringe markings permit delivery of measured fluid quantities to control the amount of lift. A second hydration port is coupled to a graduated cylinder through a valve, which is opened after lifting is complete, to measure the fluid released. A loss of fluid measured indicates a sinus tear. | 2014-02-06 |
20140038127 | Oral Care Implement With Air Flossing System - An oral care implement is disclosed comprising: an oral care region having cleaning elements; a body coupled to the oral care region; a gas outlet operably coupled to a gas source, the gas outlet disposed in the oral care region; an oral care material source storing an oral care material; an oral care material outlet operably coupled to the oral care material source, the oral care material outlet disposed in the oral care region; and wherein the oral care material outlet is spaced apart from the gas outlet. In another aspect, an oral care implement is disclosed comprising an oral care region having an elastomeric tooth cleaning element and an air outlet positioned adjacent the air outlet so that an air stream existing the air outlet causes a dynamic vibratory flexing action of at least a portion of the elastomeric tooth cleaning element. | 2014-02-06 |
20140038128 | DENTAL PIEZOELECTRIC ULTRASONIC MAGNETIC SWITCHING SCALER HANDPIECE AND METHOD OF USE - A dental piezoelectric ultrasonic magnetic switching scaler handpiece is activated by magnetic means. The dental piezoelectric scaler handpiece includes a housing that contains a fixed magnet and a magnetically activated switch. An activation magnet longitudinally slides along the outside of the housing from a de-energized position to an energized position. The activation magnet is biased to the de-energized position by the fixed magnet. When a user moves the activation magnet away from the fixed magnet and toward the magnetically activated switch, the magnetic field of the activation magnet activates the magnetically activated switch and turns the dental scaler handpiece on. | 2014-02-06 |
20140038129 | CIRCUIT BOARD FOR CONTROLLING WIRELESS DENTAL FOOT PEDAL - A system, method, and apparatus including a printed circuit board with electronic circuit components mounted thereon and configured for wireless communication between the various components and devices used in a wireless dental device. | 2014-02-06 |
20140038130 | System for Maintaining Tooth Contact During Interproximal Dental Restoration - The disclosure provides for an improved system for utilizing matrix bands in dental restorations. The system allows for maintaining or recreating close interproximal contacts between teeth following restoration. A matrix band is provided which retains in place a contact matrix that upon completion of the restoration is tightly bound to the filling matrix deposited into the cavity, and thus maintains or recreates a tight contact with adjacent teeth. The system provides an improved system for use in dental surgery, and by implementing the kit provided clinicians are able to provide enhanced results following restoration with a minimum of effort. | 2014-02-06 |
20140038131 | DENTAL FILING TOOL HANDLE - An improved handle for a dental filing tool, the tool having an arcuate handle with a horizontal bridge and opposed first and second vertical arms, the improvement including first and second sets of partial-cylindrical grip portions distributed along the outer surfaces of the first and second vertical arms, respectively, the grip portions aligned normal to the handle plane, the respective first and second sets defining convex or concave outer grip profiles and concave front-back grip profiles. An improved handle may further include an embedded socket to receive a coupler for a dental driver, or a projecting coupling to engage a dental driver coupling. | 2014-02-06 |
20140038132 | DENTAL REGENERATIVE DEVICE MADE OF POROUS METAL - A regenerative device can include a first side section, a second side section, and a top section extending between and connecting the first side section and the second side section. The top section and the first and second side sections can each be formed from a porous material that retains its structure after implantation in the patient. The regenerative device can be used for ridge augmentation of a maxilla or a mandible. The top section can include an opening configured for receiving an implant. The porous material can be permanently implanted in the mouth and promote bone regeneration or ridge augmentation. The first and second side sections of the device can include openings for receiving a fastener to secure the device to the alveolar ridge. | 2014-02-06 |
20140038133 | DENTURE RETENTION SYSTEM - A denture retention system includes a denture, abutments and an implant connected to each abutment. The denture has an inner channel with a resilient liner and engaging caps in the inner channel that releasably retain the denture on the abutments. The engaging caps each have a cavity that receives the head of an abutment. The cavities are sized with longitudinal space for the heads of the abutments so that the denture rests on the gingival tissue while the abutments restricts movement of the denture away from the gingival tissue. The system can be used with large diameter or mini implants. The separate implant and abutment allow precise selection of the abutment height. The abutment has a spherical head with tool engageable flats for tightening the abutment onto the implant. | 2014-02-06 |
20140038134 | Custom dental implants, systems, devices and methods - The invention concerns an anatomically shaped dental implant section custom shaped to fit the tooth socket of a particular individual and having a ridge circumferentially located that is complementary in size and location to a notch prepared in the tooth socket. The invention further concerns a pilot tool for the removal of soft tissue from the tooth socket prior to implantation, as well as an undercut pilot tool for placing a notch in the proximal walls of the tooth socket. The invention also concerns a dental implant system containing at least two separate dental implant sections that can be joined together to form a dental implant custom shaped to fit the tooth socket of a particular individual. The invention also concerns a method of implanting a dental implant of the present invention by sequentially positioning anatomically shaped implant sections in the root voids of the tooth socket and then joining the coronal ends of the anatomically shaped implant sections to form an anatomically shaped implant. The invention also concerns a dental implant system comprising a custom shaped dental implant, one or more soft tissue pilot tools and one or more undercut pilot tools. | 2014-02-06 |
20140038135 | METHODS, SYSTEMS AND ACCESSORIES USEFUL FOR PROCEDURES RELATING TO DENTAL IMPLANTS - A method and system are provided for manufacturing a physical dental model. A virtual model is provided representative of at least a portion of the intra-oral cavity including at least one dental implant implanted therein, and the virtual model includes a virtual portion representative of each dental implant. The virtual spatial disposition of each such virtual portion is determined with respect to the virtual model, corresponding to a real spatial disposition of the respective implant with respect to the intra oral cavity. A physical model is then manufactured based on the virtual model, the physical model including a physical analog corresponding to each implant at a respective physical spatial disposition with respect to the physical model corresponding to the respective virtual spatial disposition of the respective virtual portion with respect to the first virtual model as already determined. In some embodiments, a jig is provided configured for maintaining a desired physical spatial disposition between the physical analog and a cavity of the physical dental model at least until the physical analog is affixed in the cavity. | 2014-02-06 |
20140038136 | MARKSMANSHIP TRAINING AID - Various systems, devices, processes, and techniques may be used for marksmanship training In particular implementations, motion data for a firearm may be acquired during live operation by a firearm operator using a sensor assembly coupled to a firearm. The motion data may be analyzed to detect a firing event, and the firing event may be used to pretrigger recording of the motion data. In certain implementations, the recorded motion data may be analyzed to determine inappropriate firing control actions, if any, and to provide corrective actions to a firearm operator about inappropriate firing control actions. | 2014-02-06 |
20140038137 | TACTILE BASED PERFORMANCE ENHANCEMENT SYSTEM - A system is disclosed for communicating tactile messages to a user, such as a racecar driver, yacht crewmember, or other athlete. The system can include a tactile vest having tactile activators for conveying tactile messages to the user, including real time messages for helping the user assess and improve physical performance. The messages may be generated based on various types of sensor data, including, for example, data collected by vehicle sensors of a racecar or yacht. | 2014-02-06 |
20140038138 | DEPTH-RELATED HELP FUNCTIONS FOR A SHOVEL TRAINING SIMULATOR - Systems and methods for training an operator. One system includes a computing device including a processing unit and computer-readable medium. The computer-readable medium stores a training simulator application. The training simulator application, when executed by the processing unit, is configured to (i) receive an operating command from the operator, (ii) generate a simulated working environment and a simulated shovel having a simulated dipper, the simulated shovel and the simulated dipper positioned within the simulated working environment based on the operating command, (iii) generate an indicator providing depth-related information to an operator relating to a position of the simulated dipper with respect to a point-of-reference within the simulated working environment, and (iv) output the simulated working environment and the indicator to at least one output device for display to the operator. | 2014-02-06 |
20140038139 | TACTILE COMMUNICATION APPARATUS, METHOD, AND COMPUTER PROGRAM PRODUCT - A tactile communication apparatus that includes a signal receiver configured decode data received via a wireless signal, a tactile communication device containing a plurality of pins on one side, each pin configured to respectively move in both an outward direction and inward direction to form a plurality of pin combinations based on a plurality of activation signals, and a communication processor configured to generate the plurality of pin activation signals based on the received data so as to convey the data to a user through the plurality of pin combinations of the tactile communication device. | 2014-02-06 |
20140038140 | System for Managing the Nutritional Content for Nutritional Substances - Disclosed herein is an information encoding, marking, tracking, and transmission system for information related to nutritional substances, including nutritional content. Upon the creation of a nutritional substance, whether grown, raised, caught, collected or synthesized, information regarding the nutritional substance is accumulated, encoded and referenced to the particular nutritional substance. This information can be marked directly on the nutritional substance, but can instead be stored elsewhere, and referenced to the nutritional substance by means of a marking, unique identifier, a unique inherent property, unique genetic attribute, or an induced genetic attribute. A consumer of the nutritional substance can use this reference to retrieve the information regarding the creation of the particular nutritional substance. | 2014-02-06 |
20140038141 | USING MOBILE DEVICES IN WAGERING GAME ENVIRONMENTS - Some embodiments of the inventive subject matter include a computer-implemented method for providing tutorial content explaining a live casino table game. The method can include capturing a video stream of the live casino table game. The method can also include determining a game state for the live casino table game, wherein the game state includes a record of wagers for players of the live casino table game and results for the players of the live casino table game. The method can also include determining tutorial content based on the game state for the live casino table game, wherein the tutorial content includes information explaining strategy for the live casino table game. The method can also include transmitting a content stream including the video stream of the live casino table game and the tutorial content. | 2014-02-06 |
20140038142 | INTERACTIVE TYPE LANGUAGE LEARNING PLATFORM SYSTEM - The present invention discloses an interactive type language learning platform system applied to a display device. The interactive type language learning platform system comprises a learning interface and a video playback interface. The learning interface comprises a plurality of video options. The video playback interface comprises a video display zone and a subtitle display zone. When one of the video options is selected, the video playback zone displays video data in correspondence with the video option. The subtitle display zone synchronously displays a plurality of multi-language subtitle data in correspondence with the video date and a multi-language subtitle option respectively in correspondence with the multi-language subtitle data. When one of the multi-language subtitle options is selected, the video display zone displays a time position of the video data in correspondence with the multi-language subtitle option. Hereby, the present invention achieves the purpose of the interactive type language learning. | 2014-02-06 |
20140038143 | SYSTEMS, METHODS, AND APPARATUSES FOR MONITORING WELD QUALITY - An arc welder including an integrated monitor is disclosed. The monitor is capable of monitoring variables during a welding process and weighting the variables accordingly, quantifying overall quality of a weld, obtaining and using data indicative of a good weld, improving production and quality control for an automated welding process, teaching proper welding techniques, identifying cost savings for a welding process, and deriving optimal welding settings to be used as pre-sets for different welding processes or applications. | 2014-02-06 |
20140038144 | SYSTEMS, METHODS, AND APPARATUSES FOR MONITORING WELD QUALITY - An arc welder including an integrated monitor is disclosed. The monitor is capable of monitoring variables during a welding process and weighting the variables accordingly, quantifying overall quality of a weld, obtaining and using data indicative of a good weld, improving production and quality control for an automated welding process, teaching proper welding techniques, identifying cost savings for a welding process, and deriving optimal welding settings to be used as pre-sets for different welding processes or applications. | 2014-02-06 |
20140038145 | ADDICTION CESSATION DEVICE AND RELATED METHOD - The current invention discloses an addiction cessation device and related methods to assist a user to quit an addiction to a substance. To achieve this goal, the current invention exposes the user to negative signals whenever the urges to consume the substance arise. The addiction cessation device may be a flat surface having a back side and a front side, where the flat surface is folded so that the back side forms at least one cover page to conceal the front side, and where the front side comprises words and images that cause negative reactions to the addiction and the words and images on the front side can be revealed by unfolding the flat surface. The current invention helps the quitting efforts by revealing and displaying the images and words on the addiction cessation device to the user and providing information to associate the negative feelings created by the images or words with the addiction. By repeatedly revealing the images and words of the device when in urge of the addiction, the user may develop an association of negative reaction with the addictive substance. Additional mechanisms may involve releasing an odor that also creates negative reactions from the user. The current invention may be used to treat various kinds of addiction, such as smoking, alcohol abuse, and food addiction. | 2014-02-06 |
20140038146 | METHOD AND SYSTEM OF TEAMING UP VIA SOCIAL NETWORK SERVICE FOR ACTIVITY COACHING - A method and system of teaming via a social network service for activity coaching include creating a stage model that comprises a first and second stages, wherein a value of a performing parameter for use in the first stage is less than a value of the performing parameter for use in the second stage; receiving initial activity data of users at social network service; determining users involved in the first stage according to initial activity data; teaming the users involved in the first stage; communicating to users via social network service the value of the performing parameter for use in the second stage; setting a team goal to achieve the value; waiting for feedback from the users; determining whether the team goal is achieved; moving the users in the same team to the second stage; and providing rewards to the users, if the determination is affirmative. | 2014-02-06 |
20140038147 | Electrode for Attention Training Techniques - An electrode includes a core of beryllium copper alloy and a safe metal coating. In some embodiments, the beryllium copper alloy comprises more than three percent beryllium, less than three percent other metals and a remaining percent copper. In some embodiments, an apparatus includes a headband, and a first and second safe metal coated copper-beryllium alloy electrode. The headband is configured to fit snugly to a head of a subject in an orientation from behind a first ear, across a crown of the subject, to a position behind a second ear. The first electrode and second electrode are disposed in the headband to contact a head of the subject at a first position and a different second position, respectively, without gels. In various embodiments, the headband includes a chip to determine an analog signal and transmit data; and, a system includes the headband and a signal analyzing unit. | 2014-02-06 |
20140038148 | METHOD AND SYSTEM FOR SUPPORTING AND ENHANCING TIME MANAGEMENT SKILLS - A method and system for supporting and enhancing time management skills. Through the use of an electronic time management device, such as a cell phone or other portable digital computer based device programmed to support this method, the user enters information about a task which is then verified and “banked points” are given for correct entry. The banked points can then be used toward a socially desirable reward, such as sending text messages or playing music or watching videos. This is particularly effective in teaching time management skills to young students who may have attention deficit hyperactivity disorder (ADHD). | 2014-02-06 |
20140038149 | Chinese Meridian Health Apparel with Strips and Circles - A therapeutic outfit or body suit design that has the Chinese meridian pathways sewed in or imprinted on each piece of apparel. The Chinese meridian pathways are strips and circles that are placed at the chi energy pathways of the body. The outfit or body suit can be apparel that is snug to the body or loose on the body. The strips and circles on the therapeutic outfit or body suit are heated by the Sun (Solar) or power source. The heated strips and circles promote circulation of blood and chi through the body maintaining physical and emotional well-being. | 2014-02-06 |
20140038150 | COMPUTER-BASED COMBINED PERSONALIZED PRESCRIPTION PACKAGING AND MEDICATION COMPLIANCE SYSTEM AND METHOD WITH INCENTIVES - A computer-based system for implementing and monitoring compliance with a medication regimen, including: at least one memory element of at least one computer configured to store computer readable instructions; and at least one processor for the at least one computer configured to execute the computer readable instructions to: receive the medication regimen from a medical practitioner or a pharmacist, the medication regimen including first instructions for taking the first medication; store the medication regimen in the at least one memory element; generate at least one first compliance message regarding compliance with the first instructions; generate, using the first instructions, a first schedule for transmitting the at least one first compliance message; receive a confirmation that the first medication has been made available to a patient; and transmit, according to the first schedule, the at least one first compliance message for receipt by the patient. | 2014-02-06 |
20140038151 | SIMULATED STAPLING AND ENERGY BASED LIGATION FOR SURGICAL TRAINING - An inexpensive and practical surgical training system to train practitioners in the use of surgical stapling and energy-based ligation instruments and procedures is provided. The system comprises a modified or simulated surgical instrument such as linear surgical stapling device having a fixed anvil and an opposed, movable jaw sized and configured to be closed upon a simulated tissue structure. A marking or inking element is associated with the jaw and anvil of the stapling device and configured to impose a visible pattern on the surfaces of simulated tissue placed between the anvil and jaw. A pressure sensitive adhesive or other adhesive is associated with the inner surfaces of the simulated tissue that is activated upon compression between the anvil and jaw to simulate surgical occlusion. | 2014-02-06 |
20140038152 | MEDICAL VISUALIZATION METHOD AND SYSTEM - A system for generating a patient report of a medical consultation by a health care professional using a terminal, the method comprising the steps of, via said terminal receiving patient information data; prompting data entry of said patient condition via a graphical user interface (GUI) associated with said terminal; presenting on said GUI at least one image of the human anatomy associated with said entered patient condition; manipulating said at least one image; presenting on said GUI treatment options; storing on a computer readable medium said patient information data, said at least one image, said treatment options in a database structure; and providing said patient information data, said at least one image, said treatment options to said patient or a third party. | 2014-02-06 |
20140038153 | PATIENT SIMULATING MANNEQUIN EYE MODULE - A patient simulating mannequin has a head, at least one electronic visual display mounted to the head, and an electronic controller connected to the at least one electronic visual display. The at least one electronic visual display displays at least one of a plurality of eye images in response to a signal from the electronic controller. The plurality of eye images includes a plurality of images of pupils and at least one of iris and sclera. The plurality of images of the pupils and the at least one of iris and sclera includes images of at least one of different colors, positions and shapes of these elements. The electronic controller can control a brightness of the electronic visual display. An eye module and a method for modeling eyes of a patient simulating mannequin are also disclosed. | 2014-02-06 |
20140038154 | AUTOMATIC EBOOK READER AUGMENTATION - Method, system, and computer program product for performing an operation for automatic electronic book augmentation. The operation presents an electronic book via a display screen of an electronic device, and identifies user preferences. The operation then determines a current reading position of a user within the electronic book. The operation then identifies, based on the user's current reading position, a context within the electronic book. The operation then identifies, based on the context and the user preferences, sensory effects to enhance the user's experience. The operation then outputs the sensory effects. | 2014-02-06 |
20140038155 | Bayesian Regression Techniques for Determining True Measurements - Techniques for estimating a true measurement from a Bayesian regression on an observed measurement of received responses. | 2014-02-06 |
20140038156 | LEARNING SYSTEM AND METHOD THAT DISPLAYS ACTIVITY STREAMS BASED ON STUDENT CONTACTS - A learning management system and method delivers an instructional material to a student workstation after authenticating an student's entry into a learning session that is associated with a plurality of contacts. Stored electronic addresses in a database include a first electronic address that is associated with a first contact and a second electronic address that is associated with a second contact. The first contact is associated with the learning session and the second contact is not associated with the learning session. A first activity stream associated with the first contact and a second activity stream associated with the second contact is selectively displayed to the student such that upon detection of student's entry into the learning session, the first activity stream is displayed without displaying the second activity stream and the second activity stream is displayed upon detection of student's exit from the learning session either with displaying the first activity stream or without displaying the first activity stream. | 2014-02-06 |
20140038157 | LEARNING SYSTEM AND METHOD THAT PREVENTS COMMUNICATION OF UNAUTHORIZED CONTENT DURING A LEARNING SESSION - A learning management system and method displays a learning environment for delivery of instructional material to a remote student workstation student after authenticating a student at the remote student workstation. The learning environment displays a user interface to the student on the remote student workstation used to interact with an instructional material when the student enters into a learning session associated with a course when messages are communicated to and from the student. Communicated messages with the student are monitored to determine whether a message contains an unauthorized content and upon detection of an unauthorized content, an alert message is transmitted, for example, to an student associated with the course or to the student. | 2014-02-06 |
20140038158 | LEARNING SYSTEM AND METHOD THAT COMMUNICATES MESSAGES AMONGST GEOGRAPHICALLY DISPERSED STUDENTS BASED ON REGION PROFILES - A learning management system and method displays corresponding learning environments for delivery of instructional material to a plurality of geographically dispersed remote student workstations located in a plurality of regions after the learning system authenticates a corresponding plurality of students at the plurality of geographically dispersed remote student workstations. Each learning environment displays a user interface on a respective remote student workstation located in one region of the plurality of regions. At least one region profile stores information specifying a rule associated with communication of information between a first region and another second region. Messages are communicated amongst the geographically dispersed remote student workstations located in the plurality of regions in accordance with the region profile. | 2014-02-06 |
20140038159 | MOBILE BASED EDUCATION AND TESTING SYSTEM - A mobile based learning and testing system comprising a mobile device for mobile based learning and testing, wherein the mobile device is communicatively coupled to a server that supports retrieving educational and instructional material and testing. The mobile device comprises a downloadable educational mobile app capable of presenting educational and instructional material retrieved from the server, facilitating group interactions, providing a mock test, conducting an actual test and arranging automatic registration of a user of the mobile device based on a test result from the actual test. The downloadable educational mobile app presents the educational and instructional material (retrieved from the server, or locally) to the user of the mobile device based at least on the user's membership in a group of users, the user's membership information being maintained by the server. | 2014-02-06 |
20140038160 | PROVIDING COMPUTER AIDED SPEECH AND LANGUAGE THERAPY - A system for providing computer-aided speech and language therapy is provided herein. The system includes: a user interface configured to provide a language or a speech exercise to a patient, over a computer terminal wherein the exercise comprises at least one non multiple choice question; an analyzer configured to analyze performance of the exercise as carried out by the client, to determined a type of error, in a case of an error by the patient; and a guidance generator configured to generate a guidance instructing the patient to a correct answer to the provided exercise, wherein the guidance is generated based, at least partially, on the type of error made by the patient, wherein analyzer and the guidance generator are further configured to repeatedly analyze and generate guidance in further attempts of the patient to perform the exercise. | 2014-02-06 |
20140038161 | MULTI-LAYERED COGNITIVE TUTOR - Techniques are described for problem selection algorithms for providing a multi-layered cognitive tutor. A repository of problems is maintained, which associates the problems with the improvement of corresponding skills according to a cognitive model. User skill levels are maintained in a user profile. Problem sets are then presented to the user in phases, where each phase may utilize different selection criteria for selecting from the repository. By varying the selection criteria between phases, for example from problems testing familiar skills to problems testing new skills, or from problems teaching few skills to problems teaching many skills, problems can be selected to address the unique requirements of each tutoring phase, from beginning to middle to end. Additionally, various secondary criteria such as user interests, category and perceptual classes, problem variety, humorous problems, and other criteria may be used to integrate factors outside of the cognitive model, helping to maintain user engagement. | 2014-02-06 |
20140038162 | LEARNING SYSTEM AND METHOD THAT USES STUDENT-SELECTED AND MANDATORY CONTACTS FOR COMMUNICATING STUDENT MESSAGES - A learning management system and method that deliver instructional materials to a student stores electronic addresses for a plurality of contacts associated with the student. The student is associated with a set of student's contacts comprising at least one student-selected contact and at least one mandatory contact. A student-selected contact comprises a contact designated by the student to be in the set of student's contacts and a mandatory contact comprises a contact that is not designated by the student to be in the set of student's contacts. A user interface is provided that enables the student to select between communication of messages with the student-selected contact and the mandatory contact. | 2014-02-06 |
20140038163 | SYSTEM AND METHOD FOR CALENDARING ACTUAL DATES FOR LEARNING ACTIVITIES BASED ON A REFERENCE CALENDAR - A learning management system and method stores in a database a framework for a set of learning activities. The set of learning activities comprises a sequence of learning units that are associated with a reference calendar for completion of the learning activities relative to a reference date. The reference calendar specifies a reference due date for completing a learning activity associated with a learning unit of the sequence of learning units. The reference due date is relative to the reference date. A learning environment for delivery of instructional material associated with the sequence of learning units is displayed on a remote student workstation after the system authenticates a student at the remote student workstation. The displayed learning environment comprises a user interface that is displayed to the student on the remote student workstation. The user interface displays an actual due date, for example, in a calendar format, for completing the learning activity. The actual due date is derived from the reference due date. | 2014-02-06 |
20140038164 | LEARNING SUITE FURNITURE SYSTEM - A table assembly comprising a table including a top member and at least a first leg support member, the top member forming a substantially flat top surface and circumscribed by an outer edge, the at least one leg support member supporting the top member in a substantially horizontal position, a table dock secured to the top member and forming an elongated channel having a dock length dimension and at least a first display panel circumscribed by a panel edge and having at least one straight edge having a panel length dimension, the dock length dimension less than panel length dimension, wherein at least a portion of the straight edge of the panel is receivable within the dock channel with the panel extending out the open first and second ends of the channel to support the panel in a substantially upright orientation with at least a portion of the display panel extending to a height above the flat top surface. | 2014-02-06 |
20140038165 | PARALLELEPIPED TO TEACH TO CORRELATE A DISTINCTIVE SIGN OF A PERSONAGE TO THE RELATED PERSONAGE - The present invention concerns a parallelepiped to train to correlate the distinctive sign of a personality to its personality. | 2014-02-06 |
20140038166 | FEEDBACK CONTROL IN MICROFLUIDIC SYSTEMS - Systems and methods for controlling fluids in microfluidic systems are generally described. In some embodiments, control of fluids involves the use of feedback from one or more processes or events taking place in the microfluidic system. For instance, a detector may detect one or more fluids at a measurement zone of a microfluidic system and one or more signals, or a pattern of signals, may be generated corresponding to the fluid(s). In some cases, the signal or pattern of signals may correspond to an intensity, a duration, a position in time relative to a second position in time or relative to another process, and/or an average time period between events. Using this data, a control system may determine whether to modulate subsequent fluid flow in the microfluidic system. In some embodiments, these and other methods can be used to conduct quality control to determine abnormalities in operation of the microfluidic system. | 2014-02-06 |
20140038167 | FLUID DELIVERY SYSTEM AND METHOD - A method and apparatus for delivering one or more fluids. Fluids may be delivered sequentially from a common vessel to a chemical, biological or biochemical process. | 2014-02-06 |
20140038168 | NOVEL DRUG TARGET SITE WITHIN GP120 OF HIV - The present invention relates to a method of designing an inhibitor of the binding of HIV (human immunodeficiency virus) glycoprotein (gp)120 to a CD4-receptor or to the integrin alpha4 beta7 (a4b7). The inhibitor interacts with at least two amino acid residues comprised in six motifs within the 3-dimensional structure of gp120. Also provided are compounds, pharmaceutical compositions thereof and uses thereof in the development of an inhibitor of the binding of a HIV gp120 to a CD4-receptor or an integrin alpha4 beta7 (a4b7). The inhibitors are useful for the prevention or treatment of an HIV infection and/or diseases associated with an HIV infection. | 2014-02-06 |
20140038169 | QUANTIFICATION OF SINGLE TARGET MOLECULES IN HISTOLOGICAL SAMPLES - The present invention lies in the field of visualization and quantification of immobilized targets in samples using immunochemical means. The methods of the invention utilize an immunostaining system allowing visualizing single target units in samples as distinct dots. In particular, the invention relates to methods and reagents for visualization and quantification of molecular targets immunostained in histological samples and use of said method and reagents in medical diagnostic. However, the visualization and quantification methods of the invention are applicable to a variety of targets in different samples and allow precise quantifying both relative and absolute amounts thereof. | 2014-02-06 |
20140038170 | APPARATUS, SYSTEMS, AND METHODS FOR PERFORMING THERMAL MELT ANALYSES AND AMPLIFICATIONS - The present disclosure provides apparatus, systems, and methods for conducting rapid, accurate, and consistent heated amplifications and/or thermal melt analyses. | 2014-02-06 |
20140038171 | RAPID CELL PURIFICATION SYSTEMS - Methods and systems for purifying cells and/or viruses are provided. The sample is added to a well disposed in a medium. A potential is applied across the medium to cause the contaminants to enter one or more walls of the well, and retain the cells and/or viruses in the well. The cells and/or viruses can be removed from the well, and optionally adhered or fixed to a surface, or detected. In one embodiment, the cells and/or viruses may be retained in the well by embedding in the medium. The medium including the embedded cells and/or viruses may be excised or otherwise removed and transferred to a glass slide or other solid surface. | 2014-02-06 |
20140038172 | Matrix and System for Preserving Biological Specimens for Qualitative and Quantitative Analysis - The present invention provides a device, system, and methods of use comprising an absorbent hydrophobic polyolefin matrix, and methods of use thereof, for storage, preserving, and recovering liquid suspension of biological specimens containing analytes of interest in a dry state. The dried biological specimens containing analytes of interest absorbed on the polyolefin matrix are reconstituted such as with molecular-grade water and released by compressing the polyolefin matrix. The reconstituted biological analytes are qualified for subsequent analysis, such as for qualitative and quantitative analysis of viral nucleic acids, such a viral load testing, genotyping, and sequencing. Also provided are kits with instructions, and methods of use thereof, for storage, preserving, and recovering biological specimens containing analytes of interest using the compression device of the invention. | 2014-02-06 |
20140038173 | COMPOSITIONS, REACTION MIXTURES AND METHODS FOR DETECTING NUCLEIC ACIDS FROM MULTIPLE TYPES HUMAN PAPILLOMAVIRUS - Nucleic acid oligonucleotide sequences are disclosed which include amplification oligomers and probe oligomers which are useful for detecting multiple types of human papillomaviruses (HPV) associated with cervical cancer. Methods for detecting multiple HPV types in biological specimens by amplifying HPV nucleic acid sequences in vitro and detecting the amplified products are disclosed. | 2014-02-06 |
20140038174 | Compositions and Methods for Detecting and Identifying Nucleic Acid Sequences in Biological Samples - The invention is directed to compositions and methods for isolating, detecting, amplifying, and quantitating pathogen-specific nucleic acids in a biological sample. The invention also provides diagnostic kits containing specific amplification primers, and labeled detection probes that specifically bind to the amplification products obtained therefrom. Also disclosed are compositions and methods for the isolation and characterization of nucleic acids that are specific to one or more pathogens, including for example Influenza virus and | 2014-02-06 |
20140038175 | IN VITRO TEST METHOD FOR IMPLANT MATERIALS - The invention relates to a method for in vitro testing of specimens, such as biomaterials or implants, wherein the method comprises at least immersing at least a part of the test specimen into a liquid media, controlling the liquid media, controlling surrounding environment, providing a predetermined non-destructive force to the specimen, and measuring reactions of the specimen or constituents of the liquid media. Further it relates to an apparatus for in vitro testing. | 2014-02-06 |
20140038176 | METHOD OF DETECTING NUCLEIC ACIDS, METHOD OF OPTICALLY OBSERVING SAMPLE AND FLUORESCENT SUBSTANCE - [Object] A method of detecting nucleic acids easily without requiring complicated operations such as mixing of liquids and cleaning within micro-scale flow channels. | 2014-02-06 |
20140038177 | Brown Fat Cell Compositions and Methods - Methods of developing and using cell lines, such as stem cell lines, for therapeutic or cosmetic use. In one embodiment the cell lines are used to treat a wide range of degenerative and metabolic disorders including, but not limited to, obesity, diabetes, hypertension, and cardiac deficiency. Also described are methods of using such cell lines to screen for compounds that play a role in regulating a variety of processes. | 2014-02-06 |
20140038178 | CIS Reactive Oxygen Quenchers Integrated into Linkers - The present invention provides methods and compositions for performing illuminated reactions, particularly sequencing reactions, while mitigating and/or preventing photodamage to reactants that can result from prolonged illumination. In particular, the invention provides methods and compositions for incorporating photoprotective agents into conjugates comprising reporter molecules and nucleoside polyphosphates. | 2014-02-06 |
20140038179 | REAGENT AND REAGENT KIT FOR ANALYSIS OF IMMATURE LEUKOCYTE - The present invention provides a reagent for analysis of immature leukocytes comprising:
| 2014-02-06 |
20140038180 | DISEASE-ASSOCIATED GENETIC VARIATIONS AND METHODS FOR OBTAINING AND USING SAME - The invention provides a comprehensive, rapid, unbiased, and accurate method for identifying and/or discovering disease-associated genetic variations, e.g., disease-associated variations. The present invention further provides novel disease-associated genetic variations for use as genetic markers of disease, e.g., cancer. The invention further provides methods for assessing an individual's risk for developing a disease, e.g., cancer, by detecting the presence the novel disease-associated genetic variations of the invention. | 2014-02-06 |
20140038181 | CHEMICALLY SUBSTITUTED THERMOSENSITIVE PROBES AND COFACTORS FOR HOT START LIGATION - Provided herein are methods for ligase mediated nucleic acid replication and amplification of oligo- and probes containing substituted ligase components, particularly substituted ligase cofactors, substituted oligo- and probe acceptors, substituted oligo- and probe donors, substituted adenylated oligo- and polynucleotide donor intermediates carrying thermolabile group or groups. The substituted ligase components are not active until Hot Start activation step converts them into unsubstituted or natural ligase components, which fully support ligase reaction. The described methods are readily applied to ligation-based assays, especially utilizing Ligase Chain Reaction (LCR), for detection of a nucleic acid sequence where the use of the substituted ligase components improves an overall efficiency of LCR, increase discrimination between matched and mismatched templates and reduces or eliminates appearance of false positive signal. Furthermore, the use of the substituted ligase components reduces or eliminates the false positive signal originated from the template independent and blunt-ended ligation. | 2014-02-06 |
20140038182 | COOPERATIVE PRIMERS, PROBES, AND APPLICATIONS THEREOF - Disclosed are compositions and a method relating to amplifying and detecting nucleic acids. | 2014-02-06 |
20140038183 | 5-HYDROXYMETHYLCYTOSINE IN HUMAN CANCER - The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions useful for diagnosing or predicting cancer in a patient. In one embodiment, a method for identifying a patient as having cancer comprises the steps of (a) providing a formalin-fixed, paraffin-embedded or fresh frozen sample of patient tissue; (b) steaming the sample in antigen retrieval buffer; (c) incubating the sample in hydrochloric acid (HCl); (d) incubating the sample with an affinity reagent specific for 5hmC under conditions to form a complex between the affinity reagent and 5-hydroxymethylcytosine (5hmC) present in the sample; (e) detecting the complexes formed between 5hmC and the affinity reagent with secondary detection reagents; (f) quantifying 5hmC levels; and (g) identifying the patient as having cancer if the 5hmC levels in the sample are reduced as compared to a control. | 2014-02-06 |
20140038184 | METHODS OF DIAGNOSING CLOSTRIDIUM DIFFICILE INFECTION - Methods of diagnosing | 2014-02-06 |
20140038185 | POLYNUCLEOTIDE PRIMERS AND PROBES - The present invention provides a novel technology that involves improved primer design. These primer pairs have a wide range of applications and provide high sensitivity and specificity. | 2014-02-06 |
20140038186 | ALZHEIMER'S DISEASE-SPECIFIC ALTERATIONS OF PROTEIN KINASE C EPSILON (PKC-EPSILON) PROTEIN LEVELS - The present invention relates to methods of diagnosing Alzheimer's Disease in a human patient by detecting alterations in the ratio of PKC epsilon protein levels in a human patient compared with PKC epsilon levels in a control subject. The Alzheimer's disease-specific molecular biomarkers disclosed herein are useful for the diagnosis of Alzheimer's disease and for screening methods for the identification of compounds for treating or preventing Alzheimer's disease. The present invention also provides methods for elevating PKC epsilon protein levels comprising the steps of contacting one or more human cells with an amount of a PKC activator effective to elevate PKC epsilon levels compared to an uncontacted human cell. | 2014-02-06 |
20140038187 | THERMUS THERMOPHILUS NUCLEIC ACID POLYMERASES - The invention provides novel nucleic acid polymerases from strains GK24 and RQ-1 of | 2014-02-06 |
20140038188 | METHODS AND COMPOSITIONS FOR AMPLIFICATION OF RNA SEQUENCES - The invention provides methods for isothermal amplification of RNA. The methods are particularly suitable for amplifying a plurality of RNA species in a sample. The methods employ a composite primer, a second primer and strand displacement to generate multiple copies of DNA products comprising sequences complementary to an RNA sequence of interest. In another aspect, the methods employ a single primer (which is a composite primer) and strand displacement to generate multiple copies of DNA products comprising sequences complementary to an RNA sequence of interest. In some embodiments, a transcription step is included to generate multiple copies of sense RNA of an RNA sequence of interest. The methods are useful for preparation of nucleic acid libraries and substrates for analysis of gene expression of cells in biological samples. The invention also provides compositions and kits for practicing the amplification methods, as well as methods which use the amplification products. | 2014-02-06 |
20140038189 | METHOD OF DETERMINING HOMOZYGOTE AND HETEROZYGOTE - In order to accurately determine a homozygote and a heterozygote in a melting curve analysis, provided is an apparatus for detecting a signal from a specimen, the apparatus including a fluidic device including: a fluid path through which the specimen is passable; a reaction unit provided in the fluid path; a heater configured to elevate a temperature of the specimen in the reaction unit so as to perform the melting curve analysis; and a heater driving unit configured to drive the heater. The heater driving unit is configured to drive the heater at a first temperature elevation rate that is equal to or higher than 1° C./s and a second temperature elevation rate that is different from the first temperature elevation rate so that the fluidic device performs multiple times of the melting curve analysis for specimens including the same component. | 2014-02-06 |
20140038190 | Array Optics - An instrument is disclosed with a lens system including an objective lens system. The objective lens system is disposed between a light source and the plurality of reaction regions. The objective lens system includes a field lens array, and a pupil plane, wherein the pupil plane and the light source are located on opposite sides of the field lens array. The field lens array is disposed between the light source and the plurality of reaction regions, the field lens array including a plurality of field lens array elements, wherein the radius of the curvature, the thickness and the position of the center of the curvature of any one field lens array element in the field lens array is variable and is disposed in a light beam path between the light source and the reaction regions such that any one of the field lens array elements is capable of imaging a pupil stop located between the light source and the field lens array to a pupil located on the pupil plane, wherein an array of pupils located on the pupil plane is generated by the field lens array. | 2014-02-06 |
20140038191 | OPTICAL SYSTEM FOR HIGH RESOLUTION THERMAL MELT DETECTION - This invention relates to systems and methods for imaging sample materials within a microfluidic device during an assay reaction process. In accordance with certain aspects of the invention, images are formed with a pixel array and a region of interest (“ROI”) is defined within the pixel array. Image values, such as fluorescent intensity, can be computed as averages of individual pixel values within the ROI. Where the ROI is subject to non-uniform conditions, such as non-uniform heating, the ROI can be divided into sub-ROIs which are sufficiently small that the condition is uniform within the sub-ROI. | 2014-02-06 |
20140038192 | SYSTEM, METHOD, AND APPARATUS FOR AUTOMATED INCUBATION - System, apparatus, and method for cycling the temperature of at least one receptacle holder that is adapted for use in an automated instrument capable of performing nucleic acid-based amplification tests. Also provided are methods for conducting automated, random-access incubation processes using the same. | 2014-02-06 |
20140038193 | MICROFLUIDIC PCR DEVICE - A microfluidic device ( | 2014-02-06 |
20140038194 | Method For Early Detection of Lung Cancer - The invention provides a blood-based noninvasive early lung cancer detection method, which investigates a panel of miRNA levels in a blood or plasma sample. The panel of miRNA includes miR-17, miR-21, miR-24, miR-106a, miR-125b, miR-128, miR-155, miR-182, miR-183, miR-197, miR-199b, miR-203, miR-205, miR-210, miR-221, and a combination thereof. Preferably, the panel of miRNA may include miR-21, miR-128, miR-155, miR-182, miR-183, and miR-197. The inventive method can not only detect stage I lung cancer patients with high accuracy, but also differentiate between all stages of lung cancer patients and lung cancer-free individuals, metastatic and non-metastatic lung cancer patients and monitor the significant changes of miRNA levels during chemotherapy. | 2014-02-06 |
20140038195 | MULTIPLEXING AND QUANTIFICATION IN PCR WITH REDUCED HARDWARE AND REQUIREMENTS - Methods and algorithms for a multiplexed single detection channel amplification process and quantification of generated amplicons is presented. Various mathematical approaches for quantifying and verifying the amplicons in a reaction are presented. Usage of such methods and approaches allow upgrading of existing single and multiple channel instruments for further multiplexing capabilities. | 2014-02-06 |
20140038196 | Forming Sample Combinations Using Liquid Bridge Systems - The present invention generally relates to methods of constructing liquid bridges and methods of forming predetermined combinations of samples using liquid bridges. | 2014-02-06 |