05th week of 2009 patent applcation highlights part 44 |
Patent application number | Title | Published |
20090029414 | CELL-FREE SYNTHESIS OF MEMBRANE BOUND POLYPEPTIDES - Methods are provided for the utilization of bacterial cell-free extracts in the synthesis of high yields of membrane- associated polypeptides. | 2009-01-29 |
20090029415 | Peripheral nervous system specific sodium channels, DNA encoding therefor, crystallization, X-ray diffraction, computer molecular modeling, rational drug design, drug screening, and methods of making and using thereof - Cloning, expression, viral and delivery vectors and hosts which contain nucleic acid coding for at least one peripheral nervous system specific (PNS) sodium channel peptide (SCP), isolated PNS SCP, and compounds and compositions and methods, are provided, for isolating, crystallizing, x-ray analysing molecular modeling, rational drug designing, selecting, making and using therapeutic or diagnostic agents or ligands having at least one peripheral nervous system specific (PNS) sodium channel (SC) modulating activity. | 2009-01-29 |
20090029416 | HYPERTHERMOSTABLE PROTEASE GENE - There are provided hyperthermostable proteases having an amino acid sequences represented by SEQ ID Nos. 1, 3 and 5 of the Sequence Listing or functional equivalents thereof and hyperthermostable protease genes encoding those hyperthermostable protease. There is also disclosed a process for preparation of a hyperthermostable protease by culturing a transformant containing the gene. | 2009-01-29 |
20090029417 | Recombinant Microorganism - The object of the invention is to provide a microorganism which enhances productivity of cellulase and is useful for industrial production of cellulase, and to provide a method for producing cellulase by use of the microorganism. The present invention provides a recombinant microorganism produced by transferring a gene encoding cellulase to a parental microorganism which has been genetically modified so as to overexpress a | 2009-01-29 |
20090029418 | METHOD FOR CLONING AND EXPRESSION OF STUI RESTRICTION ENDONUCLEASE AND STUI METHYLASE IN E. COLI - The present invention relates to compositions including: (1) isolated DNA encoding the Stul restriction endonuclease and isolated DNA encoding cognate and non-cognate methylase; (2) vectors and cells containing the isolated DNA; and (3) methods for producing the Stul restriction endonuclease. | 2009-01-29 |
20090029419 | Expression of modified antibodies in avian cells - The present invention relates to construct and methods which allow the expression of immunoglobulins or functional fragments thereof which have been altered to that they are humanised. The expression of the immunoglobulins or fragments thereof takes place in avian cells, and the constructs used have been altered such that the expression levels in avian cells are higher than what would have been expected by simply using a humanised construct. The alterations are based on changing codons so that each amino acid of the codon that is used is the one which is most often found in avians. | 2009-01-29 |
20090029420 | ACID-RESISTANT SOLUBILITY TAG FOR THE EXPRESSION AND PURIFICATION OF BIOACTIVE PEPTIDES - An acid-resistant peptide solubility tag (an “inclusion body tag”) is provided that is effective in producing peptides of interest in an insoluble form. Fusion peptide constructs comprising the inclusion body tag fused to a peptide of interest are provided. An acid cleavable peptide moiety separates the inclusion body tag from the peptide of interest so that acid hydrolysis can be used during subsequent processing steps to separate the tag from the desired peptide of interest. The present inclusion body tag's resistance to acid hydrolysis facilitates easier and cleaner separation of the peptide of interest after acid hydrolysis. Specifically, a ketosteroid isomerase-derived inclusion body tag is provided that has been engineered to be more resistant to acid hydrolysis. | 2009-01-29 |
20090029421 | Recombinase polymerase amplification - The present invention features novel, diverse, hybrid and engineered recombinase enzymes, and the utility of such proteins with associated recombination factors for carrying out DNA amplification assays. The present invention also features different recombinase ‘systems’ having distinct biochemical activities in DNA amplification assays, and differing requirements for loading factors, single-stranded DNA binding proteins (SSBs), and the quantity of crowding agent employed. | 2009-01-29 |
20090029422 | REACTOR PLATE AND REACTION PROCESSING METHOD - The reactor plate preferably includes a sealed reactor, a reactor flow channel connected to the reactor, a sample container constituted from a sealed container provided separately from the reactor, a sample container flow channel to be connected to the sample container, a syringe for sending a liquid, a switching valve for connecting the syringe to the reactor flow channel or the sample container flow channel, and a projecting flow channel connected to the end of the sample container flow channel located on the sample container side. The sample container has a penetrable portion through which the projecting flow channel can penetrate and which is provided to be opposed to the projecting flow channel and is located at a position such that the projecting flow channel penetrating the penetrable portion is brought into contact with a liquid contained in the sample container. The sample container can be connected to the sample container flow channel by inserting the tip of the projecting flow channel into the sample container through the penetrable portion. | 2009-01-29 |
20090029423 | METHOD FOR SEPARATING TARGET COMPONENT - A construct in which at least a part of the magnetic material is coated with a polyhydroxyalkanoate (PHA), and a method for producing a construct by immobilizing a PHA synthesizing enzyme on the surface of the magnetic material, thereby biosynthesizing and coating a PHA. | 2009-01-29 |
20090029424 | Recombinant enzyme with altered feedback sensitivity - The present invention relates to the use of recombinant homoserine transsuccinylase enzymes with altered feedback sensitivity (MetA*) and possibly recombinant S-adenosyl methionine synthetase enzymes with reduced activity (MetK*) for the production of methionine, its precursors or derivatives thereof. | 2009-01-29 |
20090029425 | PROCESS FOR THE PRODUCTION OF BETA-LYSINE - Process for the production of -lysine by constructing a recombinant microorganism which has a deregulated lysine 2,3-aminomutase gene and at least one deregulated gene selected from the group (i) which consists of aspartokinase, aspartatesemialdehyde dehydrogenase, dihydrodipicolinate synthase, dihydrodipicolinate reductase, tetrahydrodipicolinate succinylase, succinyl-amino-ketopimelate transaminase, succinyl-diamino-pimelate desuccinylase, diaminopimelate epimerase, diamino-pimelate dehydrogenase, arginyl-tRNA synthetase, diaminopimelate decarboxylase, pyruvate carboxylase, phosphoenolpyruvate carboxylase, glucose-6-phosphate dehydrogenase, transketolase, transaldolase, 6-phosphogluconolactonase, fructose 1,6-biphosphatase, homoserine dehydrogenase, phophoenolpyruvate carboxykinase, succinyl-CoA synthetase, methylmalonyl-CoA mutase, provided that if aspartokinase is deregulated as gene (i) at least a second gene (i) other than aspartokinase has to be deregulated, and cultivating said microorganism. | 2009-01-29 |
20090029426 | PROCESS FOR PREPARING RAPAMYCIN 42-ESTERS AND FK-506 32-ESTERS WITH DICARBOXYLIC ACID, PRECURSORS FOR RAPAMYCIN CONJUGATES AND ANTIBODIES - Methods for the synthesis of regiospecific rapamycin 42-hemiesters and regiospecific FK506 32-esters with dicarboxylic acids is described. The methods involve catalyzing the reaction between a rapamycin or a FK-506 and a dicarboxylic anhydride or a bifunctional activated ester of dicarboxylic acid with a lipase. | 2009-01-29 |
20090029427 | Increased Yield in Gas-to-Liquids Processing Via Conversion of Carbon Dioxide to Diesel Via Microalge - The present invention is generally directed to systems and methods for integrating gas-to-liquids (GTL) processing with biofuels production. In some embodiments of the present invention, carbon dioxide (CO | 2009-01-29 |
20090029428 | Novel microorganism, lipid-modifying agent, and the method of manufacturing 2-acyl lysophospholipids - The present invention provides a new supply source of phospholipase A | 2009-01-29 |
20090029429 | Process for Producing Optically Active 2-Substituent-Oxy-3-(4-Substituent-Oxyphenyl) Propionic Acid Derivative - The present invention relates to a process for producing an optically active 2-substituent-oxy-3-(4-substituent-oxyphenyl)propionic acid derivative which comprises stereoselectively reducing an 2-oxo-3-(4-substituent-oxyphenyl)propionic acid by an enzyme and subjecting the thus-obtained optically active 2-hydroxy-3-(4-substituent-oxyphenyl)propionic acid to esterification of the carboxyl group according to need, then to alkylation of the hydroxyl group and, if necessary, to deprotection of an ether type protective group. The present invention may make it possible to produce an optically active 2-substituent-oxy-3-(4-substituent-oxyphenyl)propionic acid derivative, which is useful as intermediates for the synthesis of medicinal compounds, efficiently, in a simple and easy manner, and commercially advantageously. | 2009-01-29 |
20090029430 | Novel Carbonyl Reductase, Gene Therefor and Use Thereof - The present invention is to provide a process for efficiently producing an optically active alcohol including (R)-3-hydroxy-3-phenylpropanenitrile. One of the features of the present invention is a polypeptide having an activity of asymmetrically reducing 3-oxo-3-phenylpropanenitrile isolated from a microorganism belonging to the genus | 2009-01-29 |
20090029431 | PROCESS FOR THE PREPARATION OF 1,3-PROPANEDIOL BY A RECOMBINANT MICRO-ORGANISM IN THE ABSENCE OF COENZYME B12 OR ONE OF ITS PRECURSORS - The invention concerns a method for preparing 1,3-propanediol from a carbon-containing substance, said method comprising a step which consists in culturing a recombinant micro-organism not producing coenzyme B12 in the absence of coenzyme B12 or one of its precursors. The invention also concerns a nucleic acid coding for a glycerol dehydratase whereof the catalytic activity is independent of the presence of coenzyme B12 or one of its precursors and a nucleic acid coding for a 1,3-propanol dehydrogenase intervening in the synthesis of 1,3-propanediol. The invention further concerns recombinant vectors and host cells comprising said nucleic acids and the polypeptides coded by the latter. | 2009-01-29 |
20090029432 | DRY FRACTIONATION OF CORN - Novel grain processing methods and the products obtained therefrom are disclosed. Methods may include separation of pericarp fractions, hydrolysis of the pericarp fractions one or more time, and fractionation of the hydrolyzed pericarp fractions. Hydrolyzed pericarp fractions have applications including fermentation media, livestock feed, and fuel feedstocks. | 2009-01-29 |
20090029433 | HYDROGEN PRODUCING MICROORGANISM USEFUL FOR ENERGY GENERATION FROM DIVERSE CARBOHYDRATES - The disclosed invention relates to an isolated hydrogen gas producing microorganism, termed | 2009-01-29 |
20090029434 | MODULAR MEMBRANE SUPPORTED BIOREACTOR FOR CONVERSION OF SYNGAS COMPONENTS TO LIQUID PRODUCTS - A modular membrane supported bioreactor for anaerobic conversion of gas into liquid products including membrane module(s) having a plurality of hollow fibers packed across a cross sectional area of the membrane module in a direction transverse to the axis of the membrane module; a membrane vessel for retaining the membrane module(s) at least partially submerged in a process liquid and isolated from ambient atmosphere; and a gas supply conduit operably connected to the hollow fibers for supplying a process gas to the hollow fiber lumens. The gas supply conduit enables the formation of a biofilm on the outer surface of the hollow fiber wall by interaction of microorganisms with the process gas and the production of a liquid product that mixes with the process liquid. | 2009-01-29 |
20090029435 | Deactivation of Linking Moieties in Antibody-Enzyme Conjugates - In some embodiments, the present invention pertains to a method for conjugating a first compound to a second compound wherein the conjugation involves an electrophilic moiety. The method comprises reacting the first compound with the second compound to form a conjugate. The improvement in embodiments of the present invention comprises adding a nucleophilic reagent to the conjugate wherein the nucleophilic reagent forms a neutral product upon reaction with unreacted electrophilic moieties of the conjugate. In some embodiments, the nucleophilic reagent is substantially non-reactive with disulfide bonds in the event that the conjugate comprises disulfide bonds. The conjugate formed is doubly deactivated because the other moiety for linking to the electrophilic moiety is also deactivated. | 2009-01-29 |
20090029436 | SUBSTANTIALLY PURE REVERSE TRANSCRIPTASES AND METHODS OF PRODUCTION THEREOF - The present invention provides substantially pure reverse transcriptases, which are preferably substantially free from contamination with nucleic acids. The invention also provides methods for the production of these enzymes, and kits comprising these enzymes which may be used in synthesizing, amplifying or sequencing nucleic acid molecules, including through the use of the polymerase chain reaction, particularly RT-PCR. | 2009-01-29 |
20090029437 | NOVEL GLUCOSE DEHYDROGENASE AND METHOD FOR PRODUCING THE DEHYDROGENASE - A novel glucose dehydrogenase, which is an enzyme that has high substrate specificity, can be produced at a low cost, is not affected by oxygen dissolved in a measurement sample and, in particular, has superior thermal stability is obtained by culturing a microorganism belonging to the genus | 2009-01-29 |
20090029438 | COMPOSITE MATERIALS COMPRISING SUPPORTED POROUS GELS - This invention relates to a composite material that comprises a support member that has a plurality of pores extending through the support member and, located in the pores of the support member, and filling the pores of the support member, a macroporous cross-linked gel. The invention also relates to a process for preparing the composite material described above, and to its use. The composite material is suitable, for example, for separation of substances, for example by filtration or adsorption, including chromatography, for use as a support in synthesis or for use as a support for cell growth. | 2009-01-29 |
20090029439 | Regeneration - The invention relates to the filed of regeneration of cells, self-renewal of (micro-organisms), and the vegetative propagation of plant parts such as plant tissues or organs. | 2009-01-29 |
20090029440 | Lipase Variants - The invention provides variant lipases, preferably, variants with reduced tendency to odor generation obtained by introducing mutations in one or more regions identified in a parent lipase. | 2009-01-29 |
20090029441 | BIONANOMATERIALS AND THEIR SYNTHESIS - The use of biomaterials, such as viruses and virus-like particles, to form nanostructures is generally disclosed. For instance, rod-like viruses can be used to form composite nanofibers that are fixed together in a head-to-tail assembly by a polymer. Also, 2-dimensional nanostructures formed from crosslinked viruses assembled in a single, film-like layer are generally disclosed. Porous gels having controllable pore size through the use of virus particles are also disclosed. | 2009-01-29 |
20090029442 | ESTROGENIC SUBSTANCE DEGRADABLE MICROORGANISM AND USE THEREOF - A microorganism capable of degrading an estrogenic substance contained in wastewater and the like; a method for the simple and effective degradation of an estrogenic substance contained in domestic wastewater, wastewater discharged from a livestock farm, or the like by using the microorganism; and an apparatus for achieving the degradation are provided. An estrogenic substance-degrading microorganism which belongs to the genus | 2009-01-29 |
20090029443 | COMPOSITIONS AND METHODS FOR ENHANCED BACTERIAL EXOPOLYSACCHARIDE PRODUCTION - The present invention provides nucleic acid sequences and variants thereof capable of modulating exopolysaccharide production in | 2009-01-29 |
20090029444 | NOVEL RECOMBINANT ANTICOAGULANT PROTEINS - Novel recombinant anticoagulation proteins, methods of their use and methods of their production are described. In particular, recombinant fusions of annexin V (ANV) and Kunitz protease inhibitors (KPI) that possess potent anticoagulant activity are provided. The fusions, abbreviated ANV:KPI, utilize ANV having high affinity for phosphatidyl-L-serine with various KPI's to target serine proteases in membrane-associated coagulation complexes in the blood coagulation cascade. ANV:KPIs are potentially useful antithrombotic drugs permitting localized passivation of thrombogenic vessel walls and associated thrombi. | 2009-01-29 |
20090029445 | ALGAE GROWTH SYSTEM FOR OIL PRODUCTION - A biological growth reactor vessel for the cultivation of micro-algae, diatoms or other unicellular organisms, especially for oil production, is described which incorporates a dispensing rod to which are attached a plurality of clear paddles which increase surface area for the diffusion of light and growth enhancing admixtures such as CO2, nitrogen and cellulose premixed at micron level. The dispensing rod incorporates a plurality of holes strategically placed to disperse the micron-mixture slurry of the growth admixtures. The dispensing rod and its attached clear paddles make use of methods and technologies to concurrently micron mix admixtures such as natural gases, amendments and other biological factors such as enzymes and microbes to increase contact area between said mixtures and micro-algae, diatoms or other naturally occurring unicellular growth. The dispensing rod is also used in a strategic moment in time to introduce a high concentrate of micro-bubbles, micron-mixed catalase enzymes and other cellulose break-down admixtures and gases to enhance rupturing of cell walls in order to extract the maximum amount of triglyceride content from both intra and extra-cellular walls of said micro-algae, diatom or other microorganism. | 2009-01-29 |
20090029446 | Integrated Process for Conversion of Hydrocarbonaceous Assets and Photobiofuels Production - The present invention is generally directed to processes that integrate CO | 2009-01-29 |
20090029447 | Process for removing mercury from air or water - The present invention provides for the removal of mercury utilizing Mer proteins. After the Mer proteins have been expressed and isolated, or alternatively using the native Mer protein complex, either can be used as a chelating agent to remove mercury from any aqueous mercury containing environment. The Mer protein may be used in a solution to bind mercury where the solution contains a Mer proteins may be reversibly attached to a removal apparatus as a Mer ligand. The Mer complex may also be used within a bioreactor to bind and reduce Hg | 2009-01-29 |
20090029448 | Compost Heat Recovery System and Method - In a composting system for outdoor operation for large-scale composting of municipal and other wastes, one or more large compost piles or windrows are supported on a pad, and covered with a removable cover. Fluid circulation pipes are embedded within the pad, to recover heat generated by aerobic decomposition of the organic matter and to transfer the recovered heat to a region of the pad underlying an edge region of the cover. The recovered heat warms the edge region, to thaw snow and ice which may have built up on the cover at the edge region, permitting the user to easily remove the cover without damage. A computerized controller operates the system, including circulation of fluid from selected central zones to selected edge zones, with real time data collection of temperature at critical locations and optional serial extraction and application of heat from and to multiple regions on the pad. | 2009-01-29 |
20090029449 | METHOD AND APPARATUS FOR SUBSTANTIALLY ISOLATING PLANT TISSUES - The present invention discloses and claims methods and devices for the rapid mechanical isolation of monocot plant tissues suitable for transformation or tissue culture. The invention includes mechanical devices for substantially isolating target plant tissues for use as transformable explants, and propagation of transgenic plants and plant tissues. | 2009-01-29 |
20090029450 | Incubator - An accommodating unit capable of accommodating a culture vessel, a transfer unit supporting and transferring the culture vessel, and taking in and out the culture vessel relative to the accommodating unit, and an observation unit observing a sample inside of the culture vessel via an observation optical system under a state in which the culture vessel is supported by the transfer unit, are included. The transfer unit performs a positioning of each part of the sample on an optical axis of the observation optical system by moving the culture vessel at the time of observation of the sample by the observation unit. Consequently, it is possible to provide an incubator having a simple configuration. | 2009-01-29 |
20090029451 | STERILIZATION CHALLENGE SPECIMEN HOLDER - A sterilization challenge specimen holder is used with a test indicator to challenge sterilization on a consistent basis. The holder includes a body having an internal chamber region. A cap is sealable on the holder. A plug is positioned in the body. The plug has a wall having a spiral formed groove therein in communication with the internal chamber region. An opening provides for a single flow path for communication between the environs and the internal chamber via the groove. | 2009-01-29 |
20090029452 | APPARATUS AND METHOD FOR ANALYTE DETECTION - Disclosed is a testing device and methods for the identification of an analyte of interest in a sample. In a preferred embodiment, the testing device includes a front panel having at least one sample application aperture; a rear panel having at least one solvent application aperture; a sample collection matrix disposed between the rear panel and the front panel, the sample collection matrix being in communication with the sample and solvent application apertures of the front and rear panels; and at least one insertable test strip containing a reagent enabling detection of the analyte of interest. | 2009-01-29 |
20090029453 | DEVICES FOR THE DETECTION OF MULTIPLE ANALYTES IN A SAMPLE - The present invention relates generally to an assay for detecting and differentiating multiple analytes, if present, in a single fluid sample, including devices and methods therefore. | 2009-01-29 |
20090029454 | SAMPLE BLOCK APPARATUS AND METHOD FOR MAINTAINING A MICROCARD ON A SAMPLE BLOCK - A thermal cycling device for thermally cycling samples of biological material contained in a microcard having a top and bottom surface. The thermal cycling device can include a sample block having an upper surface configured for engaging the bottom surface of a microcard, a vacuum device, and a temperature control system operatively connected with the sample block. The upper surface of the sample block may include a plurality of channels, the channels defining spaces between the sample block and the bottom surface of a microcard that may be positioned thereon. The vacuum device may be in fluid communication with the sample block for drawing gas out of the spaces defined by the channels in the sample block. The vacuum device may be configured for substantially maintaining a vacuum between the sample block and microcard so that a retention force is imparted on the microcard to urge the microcard toward the sample block. Methods of maintaining a microcard on a sample block of a thermal cycling device are also provided. | 2009-01-29 |
20090029455 | CHIMERIC T1R1 TASTE RECEPTOR ENCODING NUCLEIC ACID SEQUENCES AND VECTORS - Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in taste signaling, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for representing taste perception of a particular tastant in a mammal are also described, as are methods for generating novel molecules or combinations of molecules that elicit a predetermined taste perception in a mammal, and methods for simulating one or more tastes. Further, methods for stimulating or blocking taste perception in a mammal are also disclosed. | 2009-01-29 |
20090029456 | STR50 and uses thereof - The present invention relates to use of a novel gene, STR50 and to STR50 modulators in diagnostic, therapeutic and screening aspects related to neurotoxic events. More particularly, the present invention concerns diagnosing and treating neurodegenerative diseases, and screening for species which can be useful in treating the same. | 2009-01-29 |
20090029457 | PHARMACEUTICAL COMPOSITION FOR INDUCING AN IMMUNE RESPONSE IN A HUMAN OR ANIMAL - The present invention relates to a pharmaceutical composition for inducing an immune response in a human or animal, comprising dendritic cells loaded with at least five cancer/testis antigen and no lineage specific differentiation antigens or substantially no lineage specific differentiation antigens provided from at least one cancer cell line, as well as to isolated cell lines expressing a multiplicity of cancer testis antigens and no differentiation antigens, and to a method of inducing an immune response in a human or animal using the composition of the invention. | 2009-01-29 |
20090029458 | Chicken leukemia inhibitory factor (LIF) and gene thereof - The present invention is to provide a chicken LIF gene. Based on this genetic information, LIF protein derived from the chicken can be stably supplied and it solves the problems of the creation of transgenic chickens in the past. In addition, the present invention provides not only transgenic chickens for testing purposes but also supplies the first practical transgenic stock animals. The present invention relates to leukemia inhibitory factor (LIF) shown in sequence No. 2, and the gene that encodes thereof shown in sequence No. 1, and a manufacturing method of chicken LIF. In addition, the present invention pertains to a differential preventer of the chicken differentiable cell, and a method of chicken differential prevention and a culturing method for the chicken differentiable cell using thereof, and a medium comprising thereof. | 2009-01-29 |
20090029459 | METHOD FOR THE CULTIVATION OF PRIMARY CELLS AND FOR THE AMPLIFICATION OF VIRUSES UNDER SERUM FREE CONDITIONS - The present invention relates to a method for the cultivation of primary cells. The primary cells are cultivated in a serum free medium comprising a factor selected from the group consisting of growth factors and attachment factors. The method for the cultivation of primary cells may be one step in a method for the amplification of viruses, such as poxviruses. According to this latter method the primary cells are cultivated in a serum free medium comprising a factor selected from the group consisting of growth factors and attachment factors. The cells are then infected with the virus and the infected cells are cultivated in serum free medium until progeny virus is produced. | 2009-01-29 |
20090029460 | NEOPLASM-SPECIFIC POLYPEPTIDES AND THEIR USES - The present invention features novel polypeptides and methods of using these polypeptides in the diagnosis detection, monitoring, and treatment of neoplasms in mammal, e.g., a human. | 2009-01-29 |
20090029461 | Immortalised Feeder Cells - The invention relates to an immortalized feeder cell line. The immortalized feeder cell line may be derived from an embryonic fibroblast, which may be a mouse embryonic fibroblast. A culture of an immortalized feeder cell line according to the invention in a suitable culture medium is also provided, as is a composition including an immortalized feeder cell line according to the invention in a suitable carrier or diluent and conditioned medium produced from growth of an immortalized feeder cell line according to the invention. The invention further provides a method of culturing a stem cell including use of a cell line or conditioned medium according to the invention and cells so produced. | 2009-01-29 |
20090029462 | AUTOMATED METHOD AND APPARATUS FOR EMBRYONIC STEM CELL CULTURE - The invention concerns methods for automated culture of embryonic stem cells (ESCs) such as human ESCs. In some aspects, methods of the invention employ optimized culture media and limited proteolytic treatment of cells to separate cell clusters for expansion. Automated systems for passage and expansion of ESCs are also provided. | 2009-01-29 |
20090029463 | Differentiation of Multi-Lineage Progenitor Cells to Chondrocytes - Fetal blood multi-lineage progenitor cells that are capable of a wide spectrum of transdifferentiation are described, as well as methods of differentiating the progenitor cells into chondrocytes. | 2009-01-29 |
20090029464 | Feeder Independent Extended Culture of Embryonic Stem Cells - Previous methods for culturing human embryonic stem cells have required either fibroblast feeder cells or a medium which has been exposed to fibroblast feeder cells in order to maintain the stem cells in an undifferentiated state. It has now been found that if an antagonist of bone morphogenic protein is added to the medium in which the stem cells are cultured, together with fibroblast growth factor, the stem cells will remain undifferentiated indefinitely, even without feeder cells or conditioned medium. | 2009-01-29 |
20090029465 | Culturing Human Embryonic Stem Cells - Previous methods for culturing human embryonic stem cells have required either fibroblast feeder cells or a medium which has been exposed to fibroblast feeder cells in order to maintain the stem cells in an undifferentiated state. It has now been found that if high levels of fibroblast growth factor are used in a medium with gamma amino butyric acid, pipecholic acid, lithium and lipids, the stem cells will remain undifferentiated indefinitely through multiple passages, even without feeder cells or conditioned medium. A humanized matrix of human proteins can be used as a basement matrix to culture the cells. New lines of human embryonic stem cells made using these culture conditions, the medium and the matrix, will never have been exposed to animal cells, animal products, feeder cells or conditioned medium. | 2009-01-29 |
20090029466 | METHODS AND COMPOSITIONS FOR THE SPECIFIC INHIBITION OF GENE EXPRESSION BY DOUBLE-STRANDED RNA - The invention is directed to compositions and methods for selectively reducing the expression of a gene product from a desired target gene in a cell, as well as for treating diseases caused by the expression of the gene. More particularly, the invention is directed to compositions that contain double stranded RNA (“dsRNA”), and methods for preparing them, that are capable of reducing the expression of target genes in eukaryotic cells. The dsRNA has a first oligonucleotide sequence that is between 25 and about 30 nucleotides in length and a second oligonucleotide sequence that anneals to the first sequence under biological conditions. In addition, a region of one of the sequences of the dsRNA having a sequence length of at least 19 nucleotides is sufficiently complementary to a nucleotide sequence of the RNA produced from the target gene to trigger the destruction of the target RNA by the RNAi machinery. | 2009-01-29 |
20090029467 | Method for targeting lysosomal enzymes - Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided. | 2009-01-29 |
20090029468 | ZINC FINGER BINDING DOMAINS FOR CNN - Polypeptides that contain zinc finger-nucleotide binding regions that bind to nucleotide sequences of the formula CNN are provided. Compositions containing a plurality of polypeptides, polynucleotides that encode such polypeptides and methods of regulating gene expression with such polypeptides, compositions and polynucleotide's are also provided. | 2009-01-29 |
20090029469 | Method for in vitro proliferation of dendritic cell precursors and their use to produce immunogens - A method for producing proliferating cultures of dendritic cell precursors is provided. Also provided is a method for producing mature dendritic cells in culture from the proliferating dendritic cell precursors. The cultures of mature dendritic cells provide an effective means of producing novel T cell dependent antigens comprised of dendritic cell modified antigens or dendritic cells pulsed with antigen, including particulates, which antigen is processed and expressed on the antigen-activated dendritic cell. The novel antigens of the invention may be used as immunogens for vaccines or for the treatment of disease. These antigens may also be used to treat autoimmune diseases such as juvenile diabetes and multiple sclerosis. | 2009-01-29 |
20090029470 | PROCESS AND CULTURING UNIT FOR CULTURING BIOLOGICAL CELLS - A targeted cultivation phase adjustment is provided in a process for the cultivation of cells in which biological cells are cultivated on at least one boundary surface between different, non-solid cultivation phases so that pre-determined cultivation conditions are given. A cultivation apparatus ( | 2009-01-29 |
20090029471 | Microelectromechanical devices useful for manipulating cells or embryos, kits thereof, methods of making same, and methods of use thereof - The present invention relates generally to microelectromechanical systems (MEMS) devices for the manipulation of cells or groups of cells, such as oocytes, embryos, and sperm. In particular, the present invention relates to Cell Labeling MEMS devices ( | 2009-01-29 |
20090029472 | Apparatuses and media for drug elution and methods for making and using them - Embodiments of the invention provide to apparatuses and media used in drug elution studies and methods for making and using them. Such methods and materials can be used for example to assess and control the manufacturing process variability of drug eluting implantable devices such as cardiac leads. One embodiment of the invention is a drug elution method that can be used for in-vitro studies of a matrix impregnated with a compound such as a drug blended polymer matrix. A related embodiment of the invention is an apparatus that is used for example to facilitate the practice of the above-noted methods by inhibiting the evaporation of dissolution media from the vessels in which elution is observed. | 2009-01-29 |
20090029473 | LIPID PROFILE AS A BIOMARKER FOR EARLY DETECTION OF NEUROLOGICAL DISORDERS - The present invention relates to compositions and methods for the early detection or monitoring of neurodegenerative diseases and neurological disorders including Alzheimer's disease. The invention provides biomarkers based on lipid profiles of biological samples and methods for using the biomarkers for the detection of neurodegenerative diseases and neurological disorders. | 2009-01-29 |
20090029474 | High throughput screening methods for lubricating oil compositions - A method for determining oxidation stability for a plurality of different lubricating oil composition samples is provided. The methods can advantageously be optimized using combinatorial chemistry, in which a database of combinations of lubricating oil compositions is generated. As market conditions vary and/or product requirements or customer specifications change, conditions suitable for forming desired products can be identified with little or no downtime. | 2009-01-29 |
20090029475 | METHOD FOR DETERMINING THE CONTENT OF DIESEL FUEL IN A LUBRICATING OIL OF A COMBUSTION ENGINE - A method for determining proportion of diesel fuel in a lubricating oil of a combustion engine, including: forming a mixture containing an oil sample and a C | 2009-01-29 |
20090029476 | REACTION VESSEL, ANALYZER, AND METHOD OF ANALYSIS - A reaction vessel includes a storage space extending from a first end to a second ends the reaction vessel being configured to retain at least one of a reagent and a specimen in the storage space when the at least one of the reagent and the specimen is dispensed from the first end, and to discharge the at least one of the reagent and the specimen outside the storage space from the second end when a discharge operation is performed from outside. | 2009-01-29 |
20090029477 | Ultra High-Throughput Opti-Nanopore DNA Readout Platform - Described herein are methods for analyzing polymer molecules. These methods are employed for the high throughput readout of DNA and RNA molecules with single molecule sensitivity. The method of the present invention comprises ( | 2009-01-29 |
20090029478 | DETECTION OF TARGET MOLECULES THROUGH INTERACTION WITH PROBES - A method for detecting a target nucleic acid molecule or target nucleic acid molecular complex comprising: (a) contacting two or more probes complementary to the molecule or molecular complex, said molecule or molecular complex being labeled with one or more fluorescent dye molecules of the same dye or labeled with two dyes that are indistinguishable by their emission characteristics in an assay instrument, wherein each probe interacts specifically with a different target nucleic acid sequence or a structure on the molecule or molecular complex; and (b) detecting interaction of the probes with the molecule or molecular complex, said interaction being detected by an increase in fluorescence intensity during a detection interval having a fluorescence intensity above the fluorescence intensity of any individual free probe, wherein molecule or molecular complex is analyzed such that only individual molecules or molecular complexes in contact with a probe are within an interrogation volume and within a detection time interval. | 2009-01-29 |
20090029479 | TEST STRIP AND CONNECTOR - An analyte test strip is provided that includes a generally planar substrate and a plurality of conductive areas disposed on the substrate to define five distinct conductive portions comprising at least five contact lands defining respective vertices of a polygon, and in which two contact lands are located in a single conductive portion. System and method utilizing the test strip are also described. | 2009-01-29 |
20090029480 | Testing device - A device for testing for the presence of an analyte, the device comprising at least one reagent adapted to provide a calorimetric indication in the presence of the analyte, a catalyst to catalyse the reaction providing the calorimetric indication, and where there is provided one reagent, means for substantially inhibiting reaction between reagent and catalyst or where there is provided more than one reagent, means for substantially inhibiting reaction between said reagents and between said reagents and catalyst, prior to introduction of the analyte, wherein the at least one reagent and the catalyst are solids. | 2009-01-29 |
20090029481 | Method for separating target component using magnetic nanoparticles - An object to be achieved by the present invention is to provide a method for determining the amount of a component contained in a specific lipoprotein fraction in a biological sample using an automatic analyzer, without the requirement of a step of fractionating a sample by centrifugation. The present invention provides a method for separating a target component in a biological sample, which comprises the steps of: (1) causing a biological sample to come into contact with independently dispersed magnetic nanoparticles having a particle size of 50 nm or less, which have anionic functional groups on their surfaces, so as to form an agglutinate of the magnetic nanoparticles and biomolecules capable of interacting with the magnetic nanoparticles; and (2) collecting the agglutinate by an external magnetic field. | 2009-01-29 |
20090029482 | FUNCTIONAL PARTICLE, AND METHOD FOR SEPARATION OF TARGET SUBSTANCE USING THE SAME - The particles of the present invention are high density particles which enable a preferential binding of a target substance thereto and inhibit a binding of “substances other than the target substance” thereto. The particles of the present invention are characterized in that a substance or functional group capable of binding to a target substance is immobilized on the surface of a particle body; the particles have a density of 3.5 g/cm | 2009-01-29 |
20090029483 | REAGENT FOR LATEX AGGREGATION REACTION AND METHOD FOR DETECTING TARGET SUBSTANCE - A reagent for latex aggregation reaction contains water-soluble polymer having a repeating unit presented by the following formula (1): | 2009-01-29 |
20090029484 | Novel Hemopoietin Receptor Protein, NR12 - A novel hemopoietin receptor gene (NR12) was successfully isolated by extracting motifs conserved among the amino acid sequences of known hemopoietin receptors and by using the predicted sequence. The NR12 gene encodes two forms of proteins, a transmembrane type and a soluble type. The expression of the NR12 gene was detected in tissues containing hematopoietic cells. NR12 is a novel hemopoietin receptor molecule involved in the regulation of immune system and hematopoiesis in vivo. Thus, NR12 is useful in the search for novel hematopoietic factors that functionally bind to the NR12 receptor, and in the development of therapeutic drugs for diseases associated with immunity or hematopoiesis. | 2009-01-29 |
20090029485 | MANUFACTURING METHOD OF SEMICONDUCTOR DEVICE - A capacitor in which a ferroelectric film ( | 2009-01-29 |
20090029486 | Substrate Processing Apparatus and Substrate Processing Method - A substrate processing apparatus has: a process chamber in which a substrate is processed; a heating device that optically heats the substrate accommodated in the process chamber from an outer periphery side of the substrate; a cooling device that cools the outer periphery side of the substrate by flowing a fluid in a vicinity of an outer periphery of the substrate optically heated by the heating device; a temperature detection portion that detects a temperature inside the process chamber; and a heating control portion that controls the heating device and the cooling device in such a manner so as to provide a temperature difference between a center portion of the substrate and an end portion of the substrate while maintaining a temperature at the center portion at a pre-determined temperature according to the temperature detected by the temperature detection portion. | 2009-01-29 |
20090029487 | SEMICONDUCTOR PRODUCTION METHOD AND SEMICONDUCTOR PRODUCTION DEVICE - The objective of the present invention is to prevent the variation in an ashing rate according to a temporal change within an ashing chamber. Then, in order to maintain the ashing rate, the decrease in the number of oxygen atoms in ashing gas within a process chamber | 2009-01-29 |
20090029488 | Soldering method for mounting semiconductor device on wiring board to ensure invariable gap therebetween, and soldering apparatus therefor - In a soldering method for mounting a semiconductor device on a wiring board, a plurality of solid-phase solders are provided between the semiconductor device and the wiring board, and are thermally melted to thereby produce a plurality of liquid-phase solders therebetween. A constant force is exerted on the liquid-phase solders by relatively moving the semiconductor device with respect to the wiring board so that an invariable gap is determined between the semiconductor device and the wiring board. | 2009-01-29 |
20090029489 | Endpoint Detection Device For Realizing Real-Time Control Of Plasma Reactor, Plasma Reactor With Endpoint Detection Device, And Endpoint Detection Method - An endpoint detection device, a plasma reactor with the endpoint detection device, and an endpoint detection method are provided. The endpoint detection device includes an OES data operation unit, a data selector, a product generator, an SVM, and an endpoint determiner. The OES data operation unit processes reference OES data by normalization and PCA. The data selector selects part of the linear reference loading vectors and selects part of the selected linear reference loading vectors. The product generator outputs at least one reference product value. The SVM performs regression and outputs a prediction product value. The endpoint determiner detects a process wafer etch or deposition endpoint and outputs a detection signal. | 2009-01-29 |
20090029490 | Method of fabricating an electronic device - It has been found that for silicon integrated circuits having capacitor structures or other p-n junctions structure at a technology node of 32 nm or smaller, photovoltaic induced corrosion of copper in the metallization stack is a significant issue. Thus processing conditions or device configurations are employed that preclude such corrosion. In one embodiment photovoltaic induced corrosion is monitored to prevent completion of devices with corrosion defects. | 2009-01-29 |
20090029491 | METHOD OF INSPECTING DEFECT OF SEMICONDUCTOR DEVICE - A method of inspecting defects in a semiconductor device includes forming a test pattern in a scribe lane region of a semiconductor substrate. The test pattern includes a second conductive layer formed on an isolation layer of the semiconductor substrate. Further, the method includes measuring a current flowing between the second conductive layer and the semiconductor substrate by applying a first voltage between the second conductive layer and the semiconductor substrate. Defects formed in the isolation layer can be inspected during a semiconductor manufacturing process. Accordingly, the yield of semiconductor devices can be improved with the inspection results. | 2009-01-29 |
20090029492 | Method of making light emitting diode - A method of making a light emitting diode (LED) is disclosed. The LED of the present invention comprises a semiconductor layer of a first polarity, an active layer, and a semiconductor layer of a second polarity stacked from bottom to up, wherein a stacked structure at least composed of the active layer and the semiconductor layer of the second polarity have a side with a wave-shape border in a top view of the LED and/or at least one valley, thereby increasing the efficiency of emitting the light to the outside of the LED. | 2009-01-29 |
20090029493 | Methods of Forming Light Emitting Devices with Active Layers that Extend Into Opened Pits - Light emitting devices include an active region comprising a plurality of layers and a pit opening region on which the active region is disposed. The pit opening region is configured to expand a size of openings of a plurality of pits to a size sufficient for the plurality of layers of the active region to extend into the pits. In some embodiments, the active region comprises a plurality of quantum wells. The pit opening region may comprise a superlattice structure. The pits may surround their corresponding dislocations and the plurality of layers may extend to the respective dislocations. At least one of the pits of the plurality of pits may originate in a layer disposed between the pit opening layer and a substrate on which the pit opening layer is provided. The active region may be a Group III nitride based active region. Methods of fabricating such devices are also provided. | 2009-01-29 |
20090029494 | Package structure for solid-state lighting devices and method of fabricating the same - Silicon substrates are applied to the package structure of solid-state lighting devices. Wet etching is performed to both top and bottom surfaces of the silicon substrate to form reflecting cavity and electrode access holes. Materials of the reflecting layer and electrode can be different from each other whose preferred materials can be chosen in accordance with a correspondent function. Formation of the electrode can be patterned by an etching method or a lift-off method. | 2009-01-29 |
20090029495 | Fabrication Method of GaN Power LEDs with Electrodes Formed by Composite Optical Coatings - Fabrication method of GaN power LED with electrodes formed by composite optical coatings, comprising epitaxially growing N—GaN, active, and P—GaN layers successively on a substrate; depositing a mask layer thereon; coating the mask layer with photoresist; etching the mask layer into an N—GaN electrode pattern; etching through that electrode pattern to form an N—GaN electrode region; removing the mask layer and cleaning; forming a transparent, electrically conductive film simultaneously on the P—GaN and N—GaN layers; forming P—GaN and N—GaN transparent, electrically conductive electrodes by lift-off; forming bonding pad pattern for the P—GaN and N—GaN electrodes by photolithography process; simultaneously forming thereon bonding pad regions for the P—GaN and N—GaN electrodes by stepped electron beam evaporation; forming an antireflection film pattern by photolithography process; forming an antireflection film; thinning and polishing the backside of the substrate, then forming a reflector thereon; and completing the process after scribing, packaging and testing. | 2009-01-29 |
20090029496 | RADIATION-EMITTING SEMICONDUCTOR BODY FOR A VERTICALLY EMITTING LASER AND METHOD FOR PRODUCING SAME - The present invention concerns a radiation-emitting semiconductor body with a vertical emission direction, a radiation-generating active layer, and a current-conducting layer having a current-blocking region and a current-permeable region, the semiconductor body being provided for a vertically emitting laser with an external resonator, and the external resonator having a defined resonator volume that overlaps with the current-permeable region. | 2009-01-29 |
20090029497 | SEMICONDUCTOR LIGHT-EMITTING DEVICE AND METHOD OF FABRICATING THE SAME - The invention provides a semiconductor light-emitting device with II-V group (or II-IV-V group) compound contact layer and a method of fabricating the same. The semiconductor light-emitting device according to a preferred embodiment of the invention includes a substrate, a first conductive type semiconductor material layer, a light-emitting layer, a first electrode, a second conductive type semiconductor material layer, a H-V group (or II-W-V group) compound contact layer, a transparent conductive layer, and a second electrode. The existence of the II-V group (or II-IV-V group) compound contact layer improves the ohmic contact between the second conductive type semiconductor material layer and the transparent conductive layer. | 2009-01-29 |
20090029498 | Manufacturing method of display device - To improve a deposition rate of a microcrystalline semiconductor layer by using a deposition method and to improve productivity of a display device including a TFT of a microcrystalline semiconductor, a reactive gas containing helium is supplied to a treatment chamber surrounded with a plurality of juxtaposed waveguides and a wall surface; a microwave is supplied to a space which is interposed between juxtaposed waveguides to generate plasma while the pressure of the treatment chamber is held at an atmospheric pressure or a sub-atmospheric pressure typically a pressure of 1×10 | 2009-01-29 |
20090029499 | Method for Manufacturing Nitride Semiconductor Light Emitting Element - Provided is a method for manufacturing a nitride semiconductor light emitting element. In the method, when an isolation trench for chip isolation and for laser lift-off is formed, a degradation-free nitride semiconductor light emitting element with high luminance can be formed without doing any damages to a light emitting region. In an n type nitride semiconductor layer | 2009-01-29 |
20090029500 | HERMETIC PACAKGING AND METHOD OF MANUFACTURE AND USE THEREFORE - An embodiment of the present invention provides a method of manufacturing hermetic packaging for devices on a substrate wafer, comprising forming a plurality of adhesive rings on a cap wafer or the substrate wafer, bonding the cap wafer to the substrate wafer with an adhesive layer, forming trenches in the cap wafer and the adhesive rings along outer rim of the adhesive rings, and covering sidewall of the trenches by at least one deposited film to provide a diffusion barrier to moisture or gas. | 2009-01-29 |
20090029501 | Process of Forming a Microphone Using Support Member - A method of forming a microphone forms a backplate, and a flexible diaphragm on at least a portion of a wet etch removable sacrificial layer. The method adds a wet etch resistant material, where a portion of the wet etch resistant material is positioned between the diaphragm and the backplate to support the diaphragm. Some of the wet etch resistant material is not positioned between the diaphragm and backplate. The method then removes the sacrificial material before removing any of the wet etch resistant material added during the prior noted act of adding. The wet etch resistant material then is removed substantially in its entirety after removing at least part of the sacrificial material. | 2009-01-29 |
20090029502 | APPARATUSES AND METHODS OF SUBSTRATE TEMPERATURE CONTROL DURING THIN FILM SOLAR MANUFACTURING - Embodiments of the invention generally provide apparatuses and methods of substrate temperature control during thin film solar manufacturing. In one embodiment a method for forming a thin film solar cell over a substrate is provided. The method comprises performing a temperature stabilization process on a substrate to pre-heat the substrate for a substrate stabilization time period in a first chamber, calculating a wait time period for a second chamber, wherein the wait time period is bases on the availability of the second chamber, the availability of a vacuum transfer robot adapted to transfer the substrate from the first chamber to the second chamber, or a combination of both the availability of the second chamber and the availability of the vacuum transfer robot, and adjusting the temperature stabilization time period to compensate for the loss of heat from the substrate during the wait time period. | 2009-01-29 |
20090029503 | Method for manufacturing photoelectric conversion device - To form a microcrystalline semiconductor with high quality which can be directly formed at equal to or less than 500° C. over a large substrate with high productivity without decreasing a deposition rate. In addition, to provide a photoelectric conversion device which employs the microcrystalline semiconductor as a photoelectric conversion layer. A reactive gas containing helium is supplied to a treatment chamber which is surrounded by a plurality of juxtaposed waveguides and a wall, the pressure in the treatment chamber is maintained at an atmospheric pressure or a subatmospheric pressure, microwave is supplied to a space sandwiched between the juxtaposed waveguides to generate plasma, and a photoelectric conversion layer of a microcrystalline semiconductor is deposited over a substrate which is placed in the treatment chamber. | 2009-01-29 |
20090029504 | WAFER-LEVEL ACA FLIP CHIP PACKAGE USING DOUBLE-LAYERED ACA/NCA - A method of manufacturing a wafer-level flip chip package is capable of being used to produce a flip chip package by directly coating a flip chip package using anisotropic conductive adhesives (ACA) and non conductive adhesives (NCA) in a solution state as a double layer on a wafer. The method can be used to manufacture a non-conductive mixed solution and a conductive mixed solution and directly coat them on a substrate, such that it is possible to: increase productivity; simplify a manufacturing process; suppress a shadow effect; easily perform thickness control that is difficult with the anisotropic conductive adhesive paste or the non-conductive adhesive paste; and obtain the non-conductive layer and the anisotropic conductive layer in an initial state of a B-stage with a level not losing latent of hardening through a simple drying process to volatilize an organic solvent. Above all, the non-conductive layer and the anisotropic conductive layer is sequentially stacked on the substrate formed with the non-solder bump, making it possible to make the selectivity of electrical conduction and the stability of a connection process excellent, shorten process time and costs, and dramatically reduce consumption of the conductive particles which account for a large portion of total production costs. | 2009-01-29 |
20090029505 | SEMICONDUCTOR DEVICE, MANUFACTURING METHOD FOR SEMICONDUCTOR DEVICE, ELECTRONIC COMPONENT, CIRCUIT SUBSTRATE, AND ELECTRONIC APPARATUS - A semiconductor device includes: a semiconductor substrate including a first face and a second face on a side opposite to the first face; an external connection terminal formed on the first face of the semiconductor substrate; a first electrode formed on the first face of the semiconductor substrate and electrically connected to the external connection terminal; an electronic element formed on or above the second face of the semiconductor substrate; a second electrode electrically connected to the electronic element and having a top face and a rear face; a groove portion formed on the second face of the semiconductor substrate and having a bottom face including at least part of the rear face of the second electrode; and a conductive portion formed in the groove portion and electrically connected to the rear face of the second electrode. | 2009-01-29 |
20090029506 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE - In a method of manufacturing a semiconductor device | 2009-01-29 |
20090029507 | Dielectric film, its formation method, semiconductor device using the dielectric film and its production method - A high-quality dielectric film is formed by generating plasma of a high electron density by a method such as diluting a rare gas or raising a frequency of a power supplier, and generating oxygen atoms or nitrogen atoms of a high density. The dielectric film contains silicon oxide in which the composition ratio of silicon and oxygen is between (1:1.94) and (1:2) both inclusive, silicon nitride in which the composition ratio of silicon and nitrogen is between (1:1.94) and (1:2) both inclusive, or silicon oxynitride in which the composition ratio of silicon and nitrogen is between (3:3.84) and (3:4) both inclusive. | 2009-01-29 |
20090029508 | Method for manufacturing semiconductor device - A method for manufacturing a semiconductor device and a display device each including a thin film transistor which has excellent electric characteristics and high reliability, with high mass productivity. In a display device which includes a channel-etch inversely-staggered thin film transistor in which a microcrystalline semiconductor layer is used for a channel formation region, the microcrystalline semiconductor layer is formed of a stacked layer of a microcrystalline semiconductor film which is formed by a deposition method and can be a nucleus of crystal growth and an amorphous semiconductor film; a conductive film and a semiconductor film which forms a source region and a drain region and to which an impurity imparting one conductivity is added are formed over the amorphous semiconductor film; and the conductive film is irradiated with laser light. The amorphous semiconductor film over the microcrystalline semiconductor film is crystallized by the laser light, and the microcrystalline semiconductor layer including the microcrystalline semiconductor film formed by a deposition method can be formed. | 2009-01-29 |
20090029509 | Substrate processing apparatus and method and a manufacturing method of a thin film semiconductor device - A substrate processing apparatus includes a plurality of evacuable treatment chambers connected to one another via an evacuable common chamber, and the common chamber is provided with means for transporting a substrate between each treatment chamber. More specifically, a substrate processing apparatus includes a plurality of evacuable treatment chambers, at least one of said treatment chambers having a film formation function through a vapor phase reaction therein, at least one of said treatment chambers having an annealing function with light irradiation and at least one of said treatment chambers having a heating function therein. The apparatus also has a common chamber through which said plurality of evacuable treatment chambers are connected to one another, and a transportation means provided in said common chamber for transporting a substrate between each treatment chamber. | 2009-01-29 |
20090029510 | MULTIPLE DOPING LEVEL BIPOLAR JUNCTIONS TRANSISTORS AND METHOD FOR FORMING - A process for forming bipolar junction transistors having a plurality of different collector doping densities on a semiconductor substrate and an integrated circuit comprising bipolar junction transistors having a plurality of different collector doping densities. A first group of the transistors are formed during formation of a triple well for use in providing triple well isolation for complementary metal oxide semiconductor field effect transistors also formed on the semiconductor substrate. Additional bipolar junction transistors with different collector doping densities are formed during a second doping step after forming a gate stack for the field effect transistors. Implant doping through bipolar transistor emitter windows forms bipolar transistors having different doping densities than the previously formed bipolar transistors. According to one embodiment of the present invention, bipolar junction transistors having six different collector dopant densities (and thus six different breakdown characteristics) are formed. | 2009-01-29 |
20090029511 | NOR-type channel-program channel-erase contactless flash memory on SOI - A semiconductor device having an electrically erasable programmable read only memory (EEPROM) comprises a contactless array of EEPROM memory cells disposed in rows and columns and constructed over a silicon-on-insulator wafer. Each EEPROM memory cell comprises a drain region, a source region, a gate region, and a body region. The semiconductor device further comprises a plurality of gate lines each connecting the gate regions of a row of EEPROM memory cells, a plurality of body lines each connecting the body regions of a column of EEPROM memory cells, a plurality of source lines each connecting the source regions of a column of EEPROM memory cells, and a plurality of drain lines each connecting the drain regions of a column of EEPROM memory cells. The source lines and the drain lines are buried lines, and the source regions and the drain regions of a column of EEPROM memory cells are insulated from the source regions and the drain regions of the adjacent columns of EEPROM memory cells. | 2009-01-29 |
20090029512 | SEMICONDUCTOR MEMORY HAVING CHARGE TRAPPING MEMORY CELLS AND FABRICATION METHOD THEREOF - A semiconductor memory having charge trapping memory cells and fabrication method thereof. The direction of current flow of each channel region of the memory transistors runs transversely with respect to the relevant word line, the bit lines are arranged on the top side of the word lines and in a manner electrically insulated from the latter, and electrically conductive local interconnects of source-drain regions are present, which are arranged in sections in interspaces between the word lines and in a manner electrically insulated from the latter and connected to the bit lines, wherein gate electrodes are arranged in trenches at least partly formed in the memory substrate. | 2009-01-29 |
20090029513 | VERTICAL QUADRUPLE CONDUCTION CHANNEL INSULATED GATE TRANSISTOR - A method is provided for fabricating a vertical insulated gate transistor. A horizontal isolation region is formed in a substrate to separate and electrically isolate upper and lower portions of the substrate. A vertical semiconductor pillar with one or more flanks and a cavity is formed so as to rest on the upper portion, and a dielectrically isolated gate is formed so as to include an internal portion within the cavity and an external portion resting on the flanks and on the upper portion. One or more internal walls of the cavity are coated with an isolating layer and the cavity is filled with a gate material so as to form the internal portion of the gate within the cavity and the external portion of the gate that rests on the flanks, and to form two connecting semiconductor regions extending between source and drain regions of the transistor. | 2009-01-29 |