04th week of 2011 patent applcation highlights part 40 |
Patent application number | Title | Published |
20110020740 | IMAGE FORMING APPARATUS - An image forming apparatus including a latent image bearing member, a charging device, a latent electrostatic image formation device, a development device, a transfer device, and a lubricant supplying device, the latent image bearing member satisfying (I), (II) and (III): | 2011-01-27 |
20110020741 | RESIN PARTICLE AND METHOD FOR PRODUCING THE SAME - A resin particle having a sufficiently narrow particle size distribution obtainable by using a supercritical fluid, and a production method for obtaining a resin particle having a sufficiently narrow particle size distribution by using a supercritical fluid are provided. The present invention provides a resin particle (C) having a microparticle (A) fixed to or formed as a film on a surface of a resin particle (B) containing a resin (b), wherein the degree of swelling of the microparticle (A) by liquid or supercritical carbon dioxide (X) at a temperature lower than the glass transition temperature or the melting point of the microparticle (A) is 16% or less, and the microparticle (A) is at least one kind selected from the group consisting of a crystalline resin (a1), a noncrystalline resin (a2), and an inorganic compound (a3). | 2011-01-27 |
20110020742 | PROCESS FOR PREPARING POLYMERIZED TONER - A process for preparing toner and a polymerized toner prepared thereby are provided. The process for preparing toner comprises: forming an aqueous dispersion medium comprising calcium phosphate; forming a monomer mixture of a polymer charge control agent having weight average molecular weight of about 10,000 to 20,000, pigment, and a monomer for a binder resin; dispersing the monomer mixture in the aqueous dispersion in the form of droplets; and suspension-polymerizing the monomer mixture dispersed in the form of droplets, wherein about 2 to 6 parts by weight of the calcium phosphate and about 0.6 to 10 parts by weight of the charge control agent are used, on the basis of 100 parts by weight of the monomer mixture. | 2011-01-27 |
20110020743 | BAROPLASTIC, RESIN COMPOSITION, ELECTROSTATIC-IMAGE-DEVELOPING TONER, ELECTROSTATIC IMAGE DEVELOPER, TONER CARTRIDGE, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD - A baroplastic includes a first resin with a first Tg; and a second resin with a second Tg that is lower than the first Tg by 20° C. or more, and has a photoreactive group. | 2011-01-27 |
20110020744 | METHODS FOR REDUCING PLASTICIZATION AND BLOCKING IN TONER COMPOSITIONS - Use of a wax in a toner, such as carnauba wax, to give an increase in charge control agent in a toner, such as a magenta toner, to give an increased glass transition temperature is disclosed. The toner may contain a resin comprising amorphous and crystalline polyesters to provide good low melt characteristics. | 2011-01-27 |
20110020745 | Electrostatic Image Developing Toner - The present invention relates to, in the toner including toner particles having a biding agent resin, colorings and a release agent, an electrostatic image developing toner, its composition, and a preparation method thereof. The electrostatic image developing toner is prepared by the method comprising:
| 2011-01-27 |
20110020746 | ELECTROSTATIC IMAGE DEVELOPER, DEVELOPER CARTRIDGE, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD - An electrostatic image developer is provided, the electrostatic image developer including: a carrier for an electrostatic image developer, the carrier including a core particle which has a plurality of projections on a surface of the core particle; and electrostatic image developing toners, wherein the electrostatic image developer satisfies following relationships of formulae (1) and (2): | 2011-01-27 |
20110020747 | ELECTROPHOTOGRAPHIC CARRIER, ELECTROPHOTOGRAPHIC DEVELOPER, PROCESS CARTRIDGE AND IMAGE FORMING DEVICE - An electrophotographic carrier includes a magnetic core material and a resin layer that coats the magnetic core material, the resin layer comprising a resistance control agent and a polymer including a repeating unit derived from an alicyclic group-containing methacrylic ester, the resin layer including a monomer as a base material of the repeating unit in the polymer in an amount of from about 0.5% by weight to about 3.0% by weight relative to the total amount of the resin layer. | 2011-01-27 |
20110020748 | TONER PARTICLE FOR LIQUID DEVELOPMENT AND METHOD FOR MANUFACTURING THE SAME, LIQUID DEVELOPER, LIQUID DEVELOPER CARTRIDGE, PROCESS CARTRIDGE, AND IMAGE-FORMING APPARATUS - A toner particle for liquid development is provided, the toner particle having a plurality of projections and a coat above at least a part of a surface of the toner particle, the toner particle further containing a crystal that forms at least one of the plurality of projections. | 2011-01-27 |
20110020749 | CHEMICALLY AMPLIFIED RESIST COMPOSITION AND SALT EMPLOYED THEREIN - The object of the present invention is to provide a chemically amplified resist composition excellent in a resolution and a mask error enhancement factor. | 2011-01-27 |
20110020750 | LITHOGRAPHIC IMAGING AND PRINTING WITH WET, POSITIVE-WORKING PRINTING MEMBERS - Embodiments of the present invention involve printing members that avoid ablation imaging mechanisms and, as a result, crosslinked topmost layers. Topmost layers as described herein exhibit good thermal stability and durability during printing, but can be cleaned (and thereby removed from unimaged areas) with water or aqueous cleaning fluids following imaging. It is found, in some embodiments, that the viability of certain topmost layers can be critically dependent on the nature of the underlying substrate, e.g., in terms of texture and/or surface volume. | 2011-01-27 |
20110020751 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRODUCTION PROCESS OF LITHOGRAPHIC PRINTING PLATE USING THE PRECURSOR - Provided are, as a lithographic printing plate precursor that enables good development with a developer having a pH from 2 to 10 and is excellent in runlength and stain resistance and a production process of a lithographic printing plate using the precursor, a lithographic printing plate precursor whose photosensitive layer contains the following components (A), (B), and (C):
| 2011-01-27 |
20110020752 | EXTREME ULTRAVIOLET RADIATION SOURCE AND METHOD FOR PRODUCING EXTREME ULTRAVIOLET RADIATION - A radiation source is constructed and arranged to produce extreme ultraviolet radiation. The radiation source includes a chamber, a first electrode at least partially contained in the chamber, a second electrode at least partially contained in the chamber, and a supply constructed and arranged to provide a discharge gas to the chamber. The first electrode and the second electrode are configured to create a discharge in the discharge gas to form a plasma so as to generate the extreme ultraviolet radiation. The source also includes a gas supply constructed and arranged to provide a gas at a partial pressure between about 1 Pa and about 10 Pa at a location near the discharge. The gas is selected from the group consisting of hydrogen, helium, and a mixture of hydrogen and helium. | 2011-01-27 |
20110020753 | Method for reversing tone of patterns on integrated circuit and patterning sub-lithography trenches - A method for reversing the tone of a lithographic image on a substrate comprises depositing a modifiable material on a substrate; applying a photolithographic material on the modifiable material: defining a removable patterned area in the photolithopgraphic material by photolithograpic means; removing the patterned area to produce an exposed region in the modifiable material that substantially conforms to the patterned area; producing a reacted modifiable material by increasing the etch resistance of the modifable material substantially throughout the exposed region so that the etch resistance of the exposed region comprises a region that substantially conforms to the exposed region; and removing the photoresist and the modifiable material to leave the reacted modifiable material and substrate. | 2011-01-27 |
20110020754 | METHOD OF FABRICATING A METALLIC MICROSTRUCTURE AND MICROSTRUCTURE OBTAINED VIA THE METHOD - The invention concerns a method of fabricating a metallic microstructure, characterized in that it includes the steps consisting in forming a photosensitive resin mould by a LIGA-UV type process, and in the uniform, galvanic deposition of a layer of a first metal and then a layer of a second metal form a block, which approximately reaches the top surface of the photosensitive resin. | 2011-01-27 |
20110020755 | METHOD OF FORMING PATTERNS - A method of forming patterns includes (a) coating a substrate with a resist composition for negative development to form a resist film, wherein the resist composition contains a resin capable of increasing the polarity by the action of the acid and becomes more soluble in a positive developer and less soluble in a negative developer upon irradiation with an actinic ray or radiation, (b) forming a protective film on the resist film with a protective film composition after forming the resist film and before exposing the resist film, (c) exposing the resist film via an immersion medium, and (d) performing development with a negative developer. | 2011-01-27 |
20110020756 | Calixarene Blended Molecular Glass Photoresists and Processes of Use - Photoresist compositions include a blend of at least one fully protected calix[4]resorcinarene and at least one unprotected calix[4]resorcinarene, wherein the fully protected calix[4]resorcinarene has phenolic groups protected with acid labile protective groups; a photoacid generator; and a solvent, and wherein the blend and the photoacid generator are soluble in the solvent. Also disclosed are processes for generating a resist image on a substrate using the photoresist composition. | 2011-01-27 |
20110020757 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE - To provide a method of preparing a lithographic printing plate which is safe, exhibits excellent developing property and processing ability, and enables processing with one solution by processing after image exposure, a negative lithographic printing plate precursor having an image-recording layer containing (i) a sensitizing dye, (ii) a photopolymerization initiator, (iii) an addition polymerizable compound having an ethylenically unsaturated double bond, and (iv) a binder polymer on a hydrophilic support with an aqueous solution containing a carbonate ion, a hydrogen carbonate ion and a water-soluble polymer compound. | 2011-01-27 |
20110020758 | NOVEL REACTOR FOR CARRYING OUT VERY HIGH TEMPERATURE AND HIGH PRESSURE REACTIONS - The present invention describes a novel reactor adapted for carrying out chemical reactions at temperatures of up to 1600° C., and at pressures of up to 100 bars. The reactor of the invention has two vessels surrounding the reaction zone, an inner vessel constituted by a refractory material and an outer vessel surrounding the inner vessel and constituted by an insulating material. | 2011-01-27 |
20110020759 | GAS SUPPLY INTERFACE FOR A WATER HEATER - A gas supply interface includes a door adapted to fit within an opening to a combustion chamber, the door includes a serrated opening. | 2011-01-27 |
20110020760 | COMBUSTION BURNER - A combustion burner device that includes a rotor chamber with a rotary element rotatably mounted therein. The rotor chamber has a cylindrical sidewall with an inlet port in communication with a source of pressurized gas and an outlet port in communication with a combustion chamber. The rotary element has at least two interrupters forming cavities therebetween within the rotor chamber. The cavities are configured for receiving pressurized gas from the chamber's inlet port and transferring the pressurized gas to the chamber's outlet port. The rotation of the rotary element is in response to and by way of reaction to the issuance of gas under pressure through the inlet port. | 2011-01-27 |
20110020761 | Orthodontic Repositioning Applicance - An invisible removable orthodontic repositioning appliance with a lower modulus inner lining for systematically aligning teeth from an initial tooth arrangement to a final tooth arrangement while minimizing propensity for root and bone resorption due to the lower modulus is disclosed. The aligning of the teeth may be accomplished by taking impressions at various intervals for greater accuracy in the event of a distorted impression. Patient impression and/or model may then be digitally scanned. Using 3D software, tooth position may be incrementally modified toward idealized position and associated stress analyzed. Final modified model and associated appliance may be fabricated for orthodontic movement using 3D printing. Each appliance may be numerically identified to maintain uniformity of application from start of treatment to completion. The forces required for the alignment may be from polymeric material used to fabricate the orthodontic appliances, the shape memory alloy, and/or micro-implants to accomplish optimal tooth movement. | 2011-01-27 |
20110020762 | ORTHODONTIC BRACKET - The orthodontic bracket according to the present invention is provided with ligating means having a simple configuration, has additional functions for improving therapeutic effect and improving aesthetic appearance and enables maintenance to be carried out easily. A movable slider portion | 2011-01-27 |
20110020763 | Endodontic Applications of Tissue Liquefaction - During root canal procedures, pulp may be removed from a tooth without disturbing the dentin by directing pulses of a heated liquid onto the pulp at particular temperatures and pressures to liquefy or gellify the pulp. The liquefied or gellified material is then aspirated away using the methods and apparatuses described herein. In some embodiments the heated liquid also functions to kill bacteria that may be present within the tooth. | 2011-01-27 |
20110020764 | DEVICE FOR HOLDING A MODEL SUPPORT OF AN ABUTMENT MODEL - The invention relates to a device for holding a model support of an abutment model and also to an insert ( | 2011-01-27 |
20110020765 | ULTRASONIC TIP FOR DENTAL DEVICE - A consumable tip assembly for use with a dental tool and a system for irrigation of a tooth root canal. The dental tool has an ultrasonic energy generator positioned therein. The tip assembly provides a single continuous flow path for delivering fluid from a reservoir at the proximal end of the needle to a root canal of a tooth at the distal end of the needle. Energy generated by an ultrasonic energy generator is translated into movement of a needle to provide optimum cleaning to the root canal. The system also includes a pressure source of irrigation fluid connected to the tip assembly. The irrigation fluid has ultrasonic energy imposed thereon as it passes through a hand piece of the dental tool. | 2011-01-27 |
20110020766 | Ceramic/Metallic Dental Abutment - A ceramic/metallic dental abutment for use with an implant, the abutment generally including a ceramic body portion having a base region, a transgingival region, and a supragingival region. The base region includes an anti-rotational implant interface, such as an external polygonal fitting, for engaging a cooperating internal polygonal fitting of an implant to prevent relative rotation between the abutment and the implant. The ceramic abutment body portion additionally includes a metal implant contact portion for contacting the implant and providing a load-bearing, metal-on-metal interface between the abutment and the implant. | 2011-01-27 |
20110020767 | IMPLANT WITH INTERNAL MULTI-LOBED INTERLOCK - A dental implant for supporting a dental prosthesis comprises a body portion and a top surface. The implant further comprises an internal cavity with an opening located at the top surface. The internal cavity comprises an interlock chamber having a depth measured from the top surface equal to a first distance. The interlock chamber comprising a cylindrical portion and plurality of semi-circular channels arranged around a periphery of the cylindrical portion. A threaded chamber that includes threads is located below the post-receiving chamber. The cylindrical portion has a first radius and the channels have a second radius, a ratio of the first radius to the second radius being between approximately 4:1. and 2:1. | 2011-01-27 |
20110020768 | IMPLANTABLE SCREW AND SYSTEM FOR SOCKET PRESERVATION - An implantable screw for preserving the integrity of an oral socket and for maintaining space during bone grafting procedures is provided, where the screw has a healing abutment head having a region adapted to support soft tissue, a threaded shaft and a tip adapted to penetrate bone tissue. The temporary implantable screws provided may be used in conjunction with bone graft materials and are removable for placement of an oral implant. | 2011-01-27 |
20110020769 | ORTHODONTIC IMPLANT SCREW ASSEMBLY - An orthodontic implant screw assembly, and more particularly, an orthodontic implant screw assembly that is inserted and fixed in periodontal tissues or jawbone of a human body and is pulled out by using a wire or the like so as to perform orthodontic treatment of a mouth structure. An orthodontic implant screw assembly having an improved structure in which an upper protrusion of the orthodontic implant screw assembly is detachable and replaceable according to needs so as to reduce patient's inconvenience according to operations of orthodontic treatment and so as to easily use a head having a different shape according to the operations of orthodontic treatment. When the orthodontic implant screw assembly is not temporarily used according to operations of orthodontic treatment of a mouth structure, a head having a small height and a small size can be replaced with other one so that patient's inconvenience can be reduced. Furthermore, when the orthodontic implant screw assembly including a head having a different shape according to the operations of orthodontic treatment of the mouth structure needs to be used, the orthodontic implant screw assembly is not replaced with other one but only an upper head of the orthodontic implant screw assembly is replaceable so that efficiency of orthodontic treatment can be improved and patient's inconvenience can be reduced. | 2011-01-27 |
20110020770 | DENTAL SPLINTS AND METHOD FOR USING THE SAME - This disclosure relates to a device and method for reconditioning the muscles and tissues, in particular, the gums, of an edentulous patient. | 2011-01-27 |
20110020771 | ELECTRONIC BRAILLE TYPING INTERFACE - A user interface system for entry of Braille input to electronic devices comprises a module with a single set of six tactile keys arranged in a 6 dot Braille configuration. The user interface system is configured to recognize data entered therein by user contact with one or more of the tactile keys as Braille input and to transmit said Braille input to an electronic device for display or further transmission. The interface further includes function keys which allow the user to manipulate, modify, or otherwise control the data entered and how the data is transmitted. | 2011-01-27 |
20110020772 | KIT AND METHOD FOR MAINTAINING PERSONAL WELLNESS - A wellness method, system and kit for preventing and delaying chronic diseases. In an embodiment, the wellness kit comprises stepped portions reduction and control plates, a water bottle, an elastic stretching band, a pedometer, a food and exercise log, wellness cards, a tape measure, and multimedia health information and instruction. The sequentially administered portion reduction and control plates are designed to control and reduce portion size consumption to a targeted portion size by using stepped portion reductions to normalize the reduced size. The water bottle provides visual indication of the number of bottles consumed while the stretching band increases flexibility and circulation by providing a variable resistance to a wide range of motion. To encourage physical activity and good nutrition a pedometer and a food and exercise log is used to record the use of the other tools in the method and kit. For quick reference to health information and instruction, wellness cards are included as well as a multimedia information and instruction embodied on a compact disc. | 2011-01-27 |
20110020773 | APPARATUS FOR TRAINING IN THE USE OF CHOPSTICKS - A chopsticks training apparatus has a guide having first and second ends. An indentation is provided at or near the first end of the guide. The guide has at least one surface extending between the first and second ends and forming an elongate channel. The user positions a distal tip of a first chopstick in the indentation and a distal tip of a second chopstick in the channel. With the distal tip of the first chopstick held stationary in the indentation, the user practices moving the second chopstick so that its distal tip moves away from and toward the distal tip of the first chopstick while being guided by the surfaces of the channel. | 2011-01-27 |
20110020774 | SYSTEMS AND METHODS FOR FACILITATING FOREIGN LANGUAGE INSTRUCTION - Various embodiments facilitate foreign language instruction. In one embodiment, a foreign language tutor is provided for execution on a receiving device, such as a set-top box. The foreign language tutor facilitates language instruction by enabling a user to view a received program in various languages, even though those languages may not be part of the audio or subtitles of the received program. In particular, the user may view the received program with an audio track in his/her native language and a subtitle track in a foreign language, or vice versa. In addition, the foreign language tutor is configured to obtain and display reference information (e.g., a dictionary definition) for a word of a subtitle track. This abstract is provided to comply with rules requiring an abstract, and it is submitted with the intention that it will not be used to interpret or limit the scope or meaning of the claims. | 2011-01-27 |
20110020775 | Sentence wheel - A sentence wheel comprising four circular disks, each having a different diameter. The disks are ordered sequentially, by diameter, superimposed concentrically, with an outermost portion of each disk in view. The disks are joined, by a rivet, in independently rotatable relation, about a common axis. The disk of smallest and largest diameter being a first and last disk, respectively, and the two disks of intermediate diameter being medial disks. A plurality of word sets are imprinted outwardly along a radius, in circumferentially spaced relation on the outermost portion, of each of the disks. The disks may be rotated to position one of the word sets on each disk along a common radius of the sentence wheel for forming a sentence. Pronouns or proper nouns are imprinted on the first disk, nouns are imprinted on the last disk, and auxiliary verbs, modal auxiliaries, and verbs are imprinted on the medial disks. | 2011-01-27 |
20110020776 | LOCATING EQUIPMENT FOR AND METHODS OF SIMULATING LOCATE OPERATIONS FOR TRAINING AND/OR SKILLS EVALUATION - Training systems for and methods of simulating locate operations are provided for training and/or skills evaluation. Facility locating equipment, such as on-site computers and/or locate receivers, may include modules for electronically simulating locate operations. Locating equipment including simulation modules may be used, for example, in locate technician training processes and/or for updating and/or evaluating the skills of locate technicians. In particular, a simulation module is provided for electronically generating “virtual” facilities, the presence and/or absence of which may be indicated to a locate technician during, for example, a training exercise. The actions of the locate technicians with respect to dispensing marking material that corresponds to the presence and/or absence of the virtual facilities are electronically captured, stored, and evaluated. | 2011-01-27 |
20110020777 | JURY RESEARCH SYSTEM - A system for obtaining information on individuals including jurors and providing a variety of reports via the Internet in a rapid manner. The reports can be compiled and reviewed simultaneously by multiple users and notes can be included on the report format. The user may customize the information searched and presented. | 2011-01-27 |
20110020778 | METHODS AND SYSTEMS FOR ASSESSING PSYCHOLOGICAL CHARACTERISTICS - A method for assessing a pre-cognitive emotional response from a test subject, using responses obtained during the first moments of brain activity after presentation of a stimulus, includes exposing the test subject to a visual stimulus for between approximately 500 milliseconds and approximately 1 second, and receiving an input from the subject while the subject is exposed to the visual stimulus or within approximately 300 milliseconds after the subject is first exposed to the stimulus. The method further includes storing, in response to receiving the input, a user response that identifies one of a plurality of emotional reactions that is associated with the visual stimulus. Each of the exposing, receiving, and storing acts is repeated for a plurality of visual stimuli. The method further includes determining, based on each of the stored user responses, one or more dominant emotional characteristics of the subject. | 2011-01-27 |
20110020779 | SKILL EVALUATION USING SPHERICAL MOTION MECHANISM - Software tools, methods and apparatus for objectively assessing surgical and medical procedural skills are described. Data corresponding to performance of a manipulative task by a subject is modeled using Markov modeling techniques and compared with stored models corresponding to each of a plurality of proficiency levels. A particular proficiency level is selected based on proximity of the subject data relative to each of the stored models. | 2011-01-27 |
20110020780 | DEVICE FOR SIMULATING A STOMACH OF A MONOGASTRIC MAMMAL OR OF A HUMAN BEING - The invention relates to a device for simulating the stomach of a monogastric mammal or of a human being that includes at least two compression chambers (C | 2011-01-27 |
20110020781 | On-Line Interactive Learning and Managing System - An on-line interactive learning and managing system is disclosed. The system comprises a server for a plurality of users login via the Internet. The plurality of users are allotted to form at least one learning group. The system may form correspondingly an operating interface according to each learning group for executing real-time interactive teaching between the plurality of users. The system further forms a managing interface for managing each learning group or each user's state by an administrator. The administrator uses the managing interface and each operating interface to communicate with each learning group or each user. | 2011-01-27 |
20110020782 | METHOD OF CONTROLLING COMPUTER PROGRAM AND SEARCHING FOLD AND FILE USING OBJECT-ORIENTED BUTTON, CONTROL AND PRESENTATION SYSTEM USING THE SAME AND REMOTE CONTROLLER USING THE SAME - The present invention is to provide a method of controlling a program executed on a computer using a remote control apparatus and a method of searching a folder or a file using the method of controlling the program. The method of controlling the program according to the present invention includes defining a plurality of object linking button groups in the remote control, each having an identification mark; arranging a plurality of objects each having the same identification mark as one of the plurality of object linking button groups, wherein each of the objects has a text or an image each including an execution information or a data content; assigning and interlocking the execution information with objects, respectively; transmitting a control signal to a computer by selecting one object linking button of the remote control apparatus; and selecting the execution information interlocked with corresponding object to the one object linking button after the program receives the control signal. In the present invention, since data or a file is quickly selected using an object linking button, there is advantages in processing a dynamic presentation. Moreover, a desired presentation method is easily selected and executed. | 2011-01-27 |
20110020783 | ORGANIZER MESSAGE BOARD - An article including a message board adapted for writing and posting messages thereon, and an office equipment device built into the message board. | 2011-01-27 |
20110020784 | RED FLUORESCENT PROTEINS WITH ENHANCED BACTERIAL EXPRESSION, INCREASED BRIGHTNESS AND REDUCED AGGREGATION - Polynucleotides encoding variant polypeptides of DsRed are provided herein. The DsRed variants have increased bacterial expression, reduced aggregation, increased solubility, shifted emission spectra or increased brightness relative to a wild-type DsRed. | 2011-01-27 |
20110020785 | Diagnostic Information Generation and Use - This invention relates generally to a process for producing machine readable contextual diagnostic information and use of contextual diagnostic information for generating tangible and useful results. The process provides the highest level of integration of diagnostic information collected in a distributed or centralized system comprising diagnostic devices and a global computer network. More particularly, in certain embodiments, contextual diagnostic information are used in specific diagnostic related applications and business models including ecommerce. | 2011-01-27 |
20110020786 | PEPTIDE DENDRIMERS: AFFINITY REAGENTS FOR BINDING NOROVIRUSES - Noroviruses are recognized as the most common cause of outbreaks of acute gastroenteritis in humans. Therefore, the present invention relates to peptides or dendrimers that bind Noroviruses and the methods for identifying and synthesizing these peptides. It also relates to the detection of Noroviruses using said peptides or dendrimers formed by them. | 2011-01-27 |
20110020787 | NMR DEVICE FOR DETECTION OF ANALYTES - This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient. | 2011-01-27 |
20110020788 | NMR DEVICE FOR DETECTION OF ANALYTES - This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample. The device may be used, for example, as a portable unit for point of care diagnosis and/or field use, or the device may be implanted for continuous or intermittent monitoring of one or more biological species of interest in a patient. | 2011-01-27 |
20110020789 | METHODS FOR ASSESSING FATIGUE LEVEL AND APPLICATIONS THEREOF - Level of fatigue that accompanies everyday life or a disease can be simply, easily, and quantitatively assessed by obtaining a body fluid from a test subject and measuring the amount of human herpesvirus in the body fluid. Furthermore, the anti-fatigue potency of anti-fatigue substances and anti-fatigue food products can be measured. | 2011-01-27 |
20110020790 | USE OF REGULATORY SEQUENCES FOR SPECIFIC, TRANSIENT EXPRESSION IN NEURONAL DETERMINED CELLS - The present invention relates to the use of regulatory sequences for mediating specific, early transient expression in proliferative neuronal determined cells. Furthermore, the uses of recombinant nucleic acid molecules comprising said defined regulatory sequences for mediating specific, early transient expression in proliferative neuronal determined cells as well as for the generation of non-human transgenic organisms and/or host cells are disclosed. In addition, the invention provides for transgenic non-human animals and/or host cells comprising said regulatory sequences and/or recombinant nucleic acid molecules. The invention also describes methods for the preparation of such vectors, host cells and transgenic non-human animals as well as methods for the detection and/or isolation of neuronal determined cells. Additionally, methods for screening of compounds capable of regulating neuronal determined cell activity, neurogenesis, stimulating proliferation of neuronally committed precursor cells and/or neuronal differentiation are provided and the invention also relates to methods for the detection and analysis of neuronal differentiation, neuronal migration and/or neuronal determination processes. Finally, the invention relates to diagnostic and pharmaceutical compositions comprising the regulatory sequences, recombinant nucleic acid molecules, host-cells or isolated neuronal determined cells described herein. | 2011-01-27 |
20110020791 | Methods and Materials for Detecting Mutations in Quasispecies Having Length Polymorphisms - The present invention is directed to a method for detecting the presence or absence of a mutation of interest in the nucleic acid of a pathogen, wherein the mutation of interest is located adjacent to a length polymorphism defining multiple quasispecies of the pathogen. | 2011-01-27 |
20110020792 | DETECTION OF UTERINE LEIOMYOSARCOMA USING LMP2 - This invention provides a method for detecting the presence of uterine leiomyosarcoma using the transcription or expression level of LMP2 and/or cyclin E in uterine smooth muscle tissue as an indicator and a method for detecting uterine leiomyosarcoma using LMP2 and/or cyclin E as a marker. | 2011-01-27 |
20110020793 | Molecular counting by color-coded micelles - The invention provides a method of determining ratios of target DNA molecules in a sample. A digital readout of the target DNA molecules is provided by converting ratios of target DNA molecules into equivalent ratios of amplifiable tags, which are, in turn, converted into ratios of color-coded micelles in an emulsion reaction. The micelles may be detected and counted by various methods, including by flow cytometers or slide-based imaging devices. The invention is useful for detection of relative expression levels of selected genes, gene copy number polymorphisms, allelic imbalance, relative levels of iRNAs, and related phenomena of scientific and medical interest. | 2011-01-27 |
20110020794 | METHOD FOR THE DETECTION OF DIAGNOSTIC RNA - Methods for the direct detection of diagnostic target RNA have been developed, which obviate the need for time consuming RNA purification and isolation procedures. | 2011-01-27 |
20110020795 | ANALYZING THE FMR1 GENE - A method of predicting a degree of risk of early ovarian aging of a young female. The method includes analyzing the female's FMR1 gene, wherein the FMR1 gene has a first allele and a second allele; determining the number of triple CGG repeats on each of the first and second alleles; defining a normal range of triple CGG repeats; comparing the number of triple CGG repeats on each of the first and second alleles to the normal range. If the triple CGG repeat numbers for both of the first and second alleles are within the normal range, then the female is at minimal risk for early ovarian aging. If the triple CGG repeat number for one of the first and second alleles is outside of the normal range and the other one of the first and second alleles is within the normal range, then the first and second alleles are heterozygous and the female is at increased risk for early ovarian aging. If the triple CGG repeat numbers for both of the first and second alleles are outside of the normal range, then the first and second alleles are homozygous and the female is also at an increased risk for early ovarian aging. | 2011-01-27 |
20110020796 | Compositions, Methods, and Kits for the Detection of Chlamydia Trachomatis - Method for the detection of | 2011-01-27 |
20110020797 | Methods For Identifying Patients With An Increased Likelihood Of Responding To DPP-IV Inhibitors - The invention provides novel in vitro diagnostic methods for identifying patients who may have an increased likelihood of responding to DPP-IV inhibitor therapy. The invention also provides novel polynucleotides associated with increased responsiveness of a patient to DPP-IV inhibition. Polynucleotide fragments corresponding to the genomic and/or coding regions of these polynucleotides, which comprise at least one polymorphic locus per fragment, are also provided. Allele-specific primers and probes which hybridize to these polymorphic regions, and/or which comprise at least one polymorphic locus are also provided. The polynucleotides, primers, and probes of the present invention are useful in phenotype correlations, medicine, and genetic analysis. | 2011-01-27 |
20110020798 | Novel italy, LOR-2, strife, trash, BDSF, LRSG, and STMST protein and nucleic acid molecules and uses therefor - Novel ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST proteins, the invention further provides isolated ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST fusion proteins, antigenic peptides and anti-ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST antibodies. The invention also provides ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which an ITALY, LOR-2, STRIFE, TRASH, BDSF, LRSG, and STMST gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided. | 2011-01-27 |
20110020799 | Screening method for damaged DNA repairing substance - Provided are a novel screening method for a substance that potentiates damaged DNA repair capability, based on a test with DNA repair as an index with improved sensitivity as a simplified version of the currently available unscheduled DNA synthesis (UDS) assay based on | 2011-01-27 |
20110020800 | Characterization of BBK07 antigen of Borrelia burgdorferi and methods of use - In this application is described the characterization | 2011-01-27 |
20110020801 | Carboxylesterase-1 Polymorphisms and Methods of Use Therefor - Methods and kits are provided for detecting polymorphisms in carboxylesterase-1 (CES1). Several single nucleotide polymorphisms (SNPs) in CES1 in humans, and methods for detecting the same, are provided (e.g., Gly143Glu, 12754T>del). Results indicate that the Gly143Glu (9486G>A) polymorphism has an allelic frequency of 1.5% in the Caucasian population. Polymorphisms of the present invention may alter the function of the carboxylesterase-1 enzyme (hCES1). Thus, the methods and kits of the present invention may be used to personalize a therapy and/or avoid adverse consequences of altered metabolism of a therapeutic or compound (e.g., enalapril, methylphenidate, etc.) which may result due to a CES1 polymorphism. In addition, recombinant cells lines overexpressing wild-type CES1 or expressing CES1 mutants are provided. Such cell lines may be used to assess the effects of candidate compounds on CES1, and the action of CES1 on these candidate compounds. | 2011-01-27 |
20110020802 | NUCLEIC ACIDS, METHODS AND KITS FOR THE DIAGNOSIS OF DYT6 PRIMARY TORSION DYSTONIA - The invention relates generally to the THAP1 gene and mutations in this gene, as well as the THAP1 protein and mutations in this protein, that are associated with dystonia. The invention relates to the identification, isolation, cloning and characterization of the DNA sequence corresponding to the wild type and mutant THAP1 genes, as well as isolation and characterization of their transcripts and gene products. The invention further relates to methods and kits useful for detecting mutations in THAP1 that are associated with dystonia, as well as to methods and kits useful for diagnosing dystonia. The present invention also relates to therapies for treating dystonia, including gene therapeutics and protein/antibody based therapeutics. | 2011-01-27 |
20110020803 | MARKERS FOR THE PROGNOSIS OF LUNG FUNCTION AND COLONIZATION WITH AN INFECTIOUS AGENT - The present invention provides a method and kit for determining the risk for impaired lung function and/or the susceptibility for colonization with an infectious agent. The method and kit comprise determining the presence or absence of one or more nucleic acid variants in a gene or a combination of genes. | 2011-01-27 |
20110020804 | PHOTOINDUCED ELECTRON TRANSFER (PET) PRIMER FOR NUCLEIC ACID AMPLIFICATION - This application provides photoinduced electron transfer (PET) nucleic acid molecules that can be used detect and amplify nucleic acid molecules, such as target nucleic acid molecules. These PET tags can be attached to the 5′-end of a target sequence-specific primer, thereby generating a PET primer. In particular examples, a PET tag includes a 5′-labeled nucleotide that can be quenched by at least two consecutive Gs within the tag sequence, and is unquenched when the PET tag hybridizes with its complementary nucleic acid molecule. Also disclosed are methods of using PET primers in nucleic acid amplification, such as real-time PCR. | 2011-01-27 |
20110020805 | MUTATIONAL ANALYSIS OF CHRONIC MYELOPROLIFERATIVE DISORDERS - The invention relates to molecular assays, reagents and kit for the mutational analysis, for diagnostic and prognostic purposes, of chronic myeloproliferative disorders, a group of neoplastic pathologies of the haemopoietic system. The invention relates to the identification of nucleic acid probes labelled with fluorochrome, allowing a quantitative assessment, in a specific and sensitive way, of mutation of MPL gene sequence and quantification of the mutated alleles of the MPL gene in Genomic DNA samples from patients with chronic myeloproliferative syndrome. | 2011-01-27 |
20110020806 | Rapid DNA Sequencing by Peroxidative Reaction - Disclosed is a method of polynucleic acid (e.g., DNA) sequencing which is based on the generation of pyrophosphate (PPi) that occurs when a complementary base is incorporated into a growing DNA strand being synthesized on a template. The method utilizes a cascade of enzymatic reactions catalyzed by hypoxanthine-phosphoribosyl transferase, xanthine oxidase, and peroxidase in addition to DNA polymerase and apyrase. The last chemical step in the cascade of reactions is the oxidation of a material such as an electrode or luminol by hydrogen peroxide. This generates a detectable electrical or optical signal. This method is independent of luciferase, does not require dATP analogue, and is intended to improve precision and sensitivity of DNA sequencing, and to lessen the unsynchronized polymerization. | 2011-01-27 |
20110020807 | Methylated CpG Island Amplification (MCA) - The present invention provides a method for identifying a methylated CpG containing nucleic acid by contacting a nucleic acid with a methylation sensitive restriction endonuclease that cleaves unmethylated PcG sites and contacting the sample with an isoschizomer of the methylation sensitive restriction endonuclease, which cleaves both methylated and unmethylated CpG sites. The method also includes amplification of the CpG-containing nucleic acid using CpG-specific oligonucleotide primers. A method is also provided for detecting an age associated disorder by identification of a methylated CpG containing nucleic acid. A method is further provided for evaluating the responses of a cell to an agent. A kit is useful for detection of a CpG containing nucleic acid is also provided. Nucleic acid sequences encoding novel methylated clones. | 2011-01-27 |
20110020808 | BIOMARKERS FOR DIAGNOSING SCHIZOPHRENIA AND BIPOLAR DISORDER - The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in blood and useful in diagnosing schizophrenia and/or bipolar disorder as well as monitoring therapeutic efficacy of treatment for schizophrenia or bipolar disorder. The measurement of expression levels of the products of the biomarkers and combinations of biomarkers of the invention can be used to diagnose schizophrenia and/or bipolar disorder. Measurement of the expression level of products of biomarkers of the invention using polynucleotides and proteins which specifically and/or selectively hybridize to the products of the biomarkers of the invention are also encompassed within the scope of the invention as are compositions and kits containing said polynucleotides and proteins. Further encompassed by the invention is the use of the polynucleotides and proteins to monitor the efficacy of therapeutic regimens. The invention also provides for the identification of methods of using the products of the biomarkers of the invention in the identification of novel therapeutic targets of schizophrenia and/or bipolar disorder and a method of screening the genes of said biomarkers for additional markers of disease. | 2011-01-27 |
20110020809 | MILD OSTEOARTHRITIS BIOMARKERS AND USES THEREOF - The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in individuals with mild osteoarthritis as compared with individuals without osteoarthritis. Polynucleotides and proteins which specifically and/or selectively hybridize to the products of the biomarkers of the invention are also encompassed within the scope of the invention as are kits containing said polynucleotides and proteins for use in diagnosing mild osteoarthritis. Further encompassed by the invention is the use of the polynucleotides and proteins which specifically and/or selectively hybridize to the product of the biomarkers of the invention to monitor disease regression in an individual and to monitor the efficacy of therapeutic regimens. The invention also provides for methods of using the products of the biomarkers of the invention in the identification of novel therapeutic targets for osteoarthritis. | 2011-01-27 |
20110020810 | TRPC6 INVOLVED IN GLOMERULONEPHRITIS - Focal and segmental glomerulosclerosis (FSGS) is a kidney disorder of unknown etiology and up to 20% of patients on dialysis have this diagnosis. A large family with hereditary FSGS carries a missense mutation in the TRPC6 gene on chromosome 11q, encoding the ion channel protein Transient Receptor Potential Cation Channel 6. The missense mutation is a P112Q substitution, which occurs in a highly conserved region of the protein, enhances TRPC6-mediated calcium signals in response to agonists such as angiotensin II, and alters the intracellular distribution of TRPC6 protein. Previous work has emphasized the importance of cytoskeletal and structural proteins in proteinuric kidney diseases. Our findings suggest a novel mechanism for glomerular disease pathogenesis. | 2011-01-27 |
20110020811 | HOST CELLS COMPRISING ALPHA 1,2 MANNOSIDASE AND CULTURE METHODS THEREOF - Improved host cells and culture methods involving overexpression of MAN1C1 activity to improve protein production are provided. | 2011-01-27 |
20110020812 | METHODS OF USING FET LABELED OLIGONUCLEOTIDES THAT INCLUDE A 3'-5' EXONUCLEASE RESISTANT QUENCHER DOMAIN AND COMPOSITIONS FOR PRACTICING THE SAME - Methods and compositions are provided for detecting a primer extension product in a reaction mixture. In the subject methods, a primer extension reaction is conducted in the presence of a polymerase having 3′→5′ exonuclease activity and at least one FET labeled oligonucleotide probe that includes a 3′→5′ exonuclease resistant quencher domain. Also provided are systems and kits for practicing the subject methods. The subject invention finds use in a variety of different applications, and are particularly suited for use in high fidelity PCR based reactions, including SNP detection applications, allelic variation detection applications, and the like. | 2011-01-27 |
20110020813 | ADVANCED PATHOGEN DETECTION AND SCREENING - Disclosed is a rapid, dual purpose, PCR-based method for identifying two or more pathogens, including | 2011-01-27 |
20110020814 | METHODS AND COMPOSITIONS FOR SELECTION OF STEM CELLS - Described herein are methods and compositions for selection of pluripotent stem cells from a population of mammalian cells (e.g., human) undergoing a process that induces some cells within the population to become pluripotent. | 2011-01-27 |
20110020815 | METHODS FOR GENOMIC ANALYSIS - The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis. | 2011-01-27 |
20110020816 | Precursor miRNA loop-modulated target regulation - By modifying nucleotides from either or both the stem and loop of precursor-miRNA, greater specificity is achieved as to the mRNAs targeted. The improved efficiency in target regulation can be either mediated by direct base-pairings between targets and precursor miRNAs or indirectly by energy constraints on the availability of such base-pairings. It is found that pri- and pre-miRNA are active in the absence of functional mature miRNA, so pri- or pre-miRNA or truncated portion thereof, but not as mature miRNA, can be used as RNAi agents by themselves. Furthermore, besides the seed sequence of the stem of the pre-miRNA and 3′-extensions thereof to provide greater complementarity to the target mRNA, nucleotides in the loop can affect the activity and specificity of the precursor-miRNA and the processing and binding to target mRNA. By using mutated sequences in the natural pri- or pre-miRNA or modified mimetics, one can screen for target mRNA, target a unique mRNA or a group of mRNAs for regulation, and modulate cell properties with greater specificity and investigate cellular activity as to phenotype and response to external stimuli in the presence or absence of at least partial target protein expression. | 2011-01-27 |
20110020817 | De novo synthesized plasmid, methods of making and use thereof - The invention relates to a de novo synthesized plasmid. The plasmid comprises relevant sequences for plasmid replication and plasmid selection. The methods of making and use of the plasmid are disclosed. The plasmid can be used to make other plasmids. These plasmids and their host cells can be used for biomedical applications. | 2011-01-27 |
20110020818 | REACTOR FOR THE QUANTITATIVE ANALYSIS OF NECLEIC ACIDS - A reactor for the quantitative analysis of target nucleic acids using an evanescent wave detection technique and a method of use thereof is provided. The reactor includes a substrate with a cavity, a buffer layer arranged over the substrate; a cover plate arranged over the buffer layer, and inlet and outlet ports. The reactor is thermally and chemically stable for PCR processing and suitable for an evanescent wave detection technique. | 2011-01-27 |
20110020819 | ISOTHERMAL DETECTION METHODS AND USES THEREOF - The present disclosure relates to methods and probes for rapid, single temperature (isothermal) detection of specific nucleic acid sequences. The methods and probes provide a simple method for detecting bioagents including bacteria and viruses, and the detection of specific genetic markers on any nucleic sequence. | 2011-01-27 |
20110020820 | METHOD FOR DETECTION OF MICROORGANISM AND KIT FOR DETECTION OF MICROORGANISM - A kit is disclosed for preparing a measurement sample for detecting live cells, injured cells, VNC cells and dead microorganism cells in a test sample by the following steps:
| 2011-01-27 |
20110020821 | METHOD FOR DETECTION OF MICROORGANISM AND KIT FOR DETECTION OF MICROORGANISM - According to the following steps, live cells, injured cells, VNC cells and dead cells of a microorganism in a test sample are detected by flow cytometry:
| 2011-01-27 |
20110020822 | MOLECULAR DETECTION OF CHROMOSOME ABERRATIONS - The invention relates to the field of cytogenetics and the application of genetic diagnostic techniques in pathology and hematology. Specifically, the invention relates to nucleic acid probes that can be used in hybridization techniques for the detection of chromosomal aberrations and other gene rearrangements such as immunoglobulin and T-cell receptor gene rearrangements. The probes provided by the invention are a distinct and balanced set of probes of comparable size, each preferably being from 1 to 100 kb, or smaller, and flanking a potential breakpoint in a chromosome. | 2011-01-27 |
20110020823 | SEQUENCES AND THEIR USE FOR DETECTION AND CHARACTERIZATION OF E. COLI O157:H7 - This invention relates to a rapid method for detection and characterization of | 2011-01-27 |
20110020824 | METHODS AND COMPOSITIONS FOR QUANTITATIVE AMPLIFICATION AND DETECTION OVER A WIDE DYNAMIC RANGE - Disclosed are compositions and methods for making differentiable amplicon species at unequal ratios using a single amplification system in a single vessel. The number of differentiable amplicons and their ratios to one another are chosen to span the required linear dynamic range for the amplification reaction and to accommodate limitations of the measuring system used to determine the amount of amplicon generated. Unequal amounts of distinguishable amplicon species are generated by providing unequal amounts of one or more amplification reaction components (e.g., distinguishable amplification oligomers, natural and unnatural NTP in an NTP mix, or the like). The amount of target nucleic acid present in a test sample is determined using the linear detection range generated from detection of one or more amplicon species having an amount within the dynamic range of detection. | 2011-01-27 |
20110020825 | PROTEIN C POLYMORPHISMS USEFUL AS AN INDICATOR OF PATIENT OUTCOME - The invention provides methods and kits for obtaining a prognosis for a patient having or at risk of developing an inflammatory condition. The method generally comprises determining a protein C promoter genotype of a patient for a polymorphism in the protein C promoter region of the patient, comparing the determined genotype with known genotypes for the polymorphism that correspond with the ability of the patient to recover from the inflammatory condition and identifying patients based on their prognosis. The invention also provides for methods of identifying other polymorphisms that correspond with the ability of the patient to recover from the inflammatory condition. | 2011-01-27 |
20110020826 | METHODS FOR ASSESSING EFFICACY OF CHEMOTHERAPEUTIC AGENTS - Methods are provided for accurately predicting efficacy of chemotherapeutic agents. Methods of the invention increase the positive predictive value of chemosensitivity assays by assessing both the ability of a chemotherapeutic to destroy cells and the genetic propensity of those cells for resistance. Results obtained using methods of the invention provide insight into the in vivo effectiveness of a therapeutic, and lead to more effective chemotherapeutic treatment. | 2011-01-27 |
20110020827 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USES THEREOF - The invention is directed to modified guanine-containing nucleosides and nucleotides and uses thereof. More specifically, the invention relates to modified fluorescently labelled guanine-containing nucleosides and nucleotides which exhibit enhanced fluorophore intensity by virtue of reduced quenching effects. | 2011-01-27 |
20110020828 | CE43-67B INSECTICIDAL COTTON - The present application relates an insect resistant transgenic cotton plant. In particular, it relates to a specific event, designated CE43-67B. The application also relates to polynucleotides which are characteristic of the CE43-67B event, plants comprising said polynucleotides, and methods of detecting the CE43-67B event. | 2011-01-27 |
20110020829 | RAPID ASSAY FOR DETECTING ATAXIA-TELANGIECTASIA HOMOZYGOTES AND HETEROZYGOTES - The present disclosure relates to methods for performing an assay to identify ataxia-telangiectasia homozygotes or heterozygotes. Some embodiments include the use of a rapid flow cytometry-based ataxiatelangiectasia (ATM) kinase assay that measures ATM-dependent phosphorylation of SMC1 following DNA damage. | 2011-01-27 |
20110020830 | DESIGN FOR RAPIDLY CLONING ONE OR MORE POLYPEPTIDE CHAINS INTO AN EXPRESSION SYSTEM - The present invention provides methods and compositions for the generation and identification of expression constructs that can be used to express sufficient levels of a polypeptide of interest. The compositions include a population of expression vectors, wherein members of the population have a type IIS restriction enzyme recognition site adjacent to a regulatory sequence, and wherein the regulatory element is distinct in at least two members of the population of expression vectors. In various embodiments, the expression vectors further comprise a polynucleotide sequence encoding a polypeptide of interest, wherein the polynucleotide encoding the polypeptide, the polynucleotide of the regulatory sequence, or both, are distinct in at least two members of the population. The compositions are useful for identifying a combination of coding sequences and/or regulatory elements useful for the heterologous expression of the polypeptide of interest. | 2011-01-27 |
20110020831 | GENETIC DETECTION OF HIV-1 STRAINS THAT USE THE CXCR4 CO-RECEPTOR - The invention relates to a method for obtaining clonal HIV-1 sequence information from a clinical isolate derived from an HIV-1 infected individual to guide highly active anti-retroviral therapy (HAART) comprising the following steps;
| 2011-01-27 |
20110020832 | METHOD FOR DETECTING CANCER CELL CAUSED BY HPV, METHOD FOR DETERMINING WHETHER OR NOT TISSUE IS AT STAGE OF HIGH-GRADE DYSPLASIA OR MORE SEVERE STAGE, AND PRIMER SET AND KIT USED THEREFOR - Provided are a primer set, a method and a kit therefor, which can easily perform with high accuracy the detection of a cancer cell caused by HPV and the determination of whether or not a tissue is a tissue with high-grade dysplasia or in a more severe phase. As a primer set, used is a primer set consisting of a first primer which hybridizes with a nucleic acid consisting of a nucleotide sequence in which cytosine present in a site other than a CpG site is converted into another base in a nucleotide sequence having a CpG site in L1 region or L2 region of HPV and a second primer which hybridizes with a nucleic acid consisting of a nucleotide sequence in which cytosine is converted into another base in a nucleotide sequence having a CpG site in LCR or E6 region of HPV. | 2011-01-27 |
20110020833 | Method for Detecting Analytes - The subject of this invention is a process for detection of analytes from biological samples comprising the following process steps:
| 2011-01-27 |
20110020834 | HIGH SENSITIVITY MECHANICAL RESONANT SENSOR - A system and method for detecting mass based on a frequency differential of a resonating micromachined structure, such as a cantilever beam. A high aspect ratio cantilever beam is coated with an immobilized binding partner that couples to a predetermined cell or molecule. A first resonant frequency is determined for the cantilever having the immobilized binding partner. Upon exposure of the cantilever to a solution that binds with the binding partner, the mass of the cantilever beam increases. A second resonant frequency is determined and the differential resonant frequency provides the basis for detecting the target cell or molecule. The cantilever may be driven externally or by ambient noise. The frequency response of the beam can be determined optically using reflected light and two photodetectors or by interference using a single photodetector. | 2011-01-27 |
20110020835 | Device and Method for Detecting Small Quantities of Light, Comprising an Electronic Image Converter Embodied in Semiconductor Technology - The invention relates to a device for detecting small quantities of light, comprising an electronic image converter embodied in semiconductor technology for detecting the photons representing the small quantities of light and an electronic circuit connected to the electronic image converter for reading the electronic image converter and for generating a signal representing the number of photons received by the electronic image converter, wherein the electronic image converter comprises at least 100,000 light-sensitive cells and the electronic circuit is adapted to add together the signals coming from light-sensitive cells placed on the electronic image converter. | 2011-01-27 |
20110020836 | PROCESS FOR DIFFERENTIAL POLYPEPTIDES DETECTION AND USES THEREOF - Provided herein is an affinity media and the construction and use thereof. The affinity media may be used, for example, for the detection of differential proteins/peptides by depletion of proteins/peptides similar to those in a control sample from a test sample in the search for biologically and pathologically important proteins/peptides. The detected differential proteins/peptides provide vital information for biomarker discovery, drug target discovery, and personalized medicine and treatment. | 2011-01-27 |
20110020837 | Method for isolating or identifying a target protein interacting with a lipid in a cell - The invention is in the field of molecular biology and cell biology. It provides tools and methods for studying the interaction of proteins and lipids in vivo as well as in vitro. The invention relates to a method for isolating or identifying a target protein interacting with a lipid in a cell. This method employs novel dual-labeled lipid precursors such as fatty acids or their derivatives. These lipid precurors comprise two functional groups: a photoactivatable group, such as a diazirine ring, as well as a terminal alkyne or azide moiety. | 2011-01-27 |
20110020838 | MOLECULES FOR THE TREATMENT OF LUNG DISEASE INVOLVING AN IMMUNE REACTION TO CONNECTIVE TISSUE FOUND IN THE LUNG - Various embodiments include methods for diagnosing and treating medical conditions that involve an autoimmune response to connective tissue such as collagen found in organs such as the lung. In one method pulmonary disease and disorders such as Idiopathic Pulmonary Fibrosis (IPF) are diagnosed by analyzing fluid or tissue samples obtained from a patient for evidence of an autoimmune response to various types of collagen including, for example, Type V. One type of assay for evidence of an autoimmune response to Type V collagen comprises the steps of obtaining a fluid or tissue sample from a patient, contacting at least a portion of the sample with antigen to anti-Type V collagen antibody and monitoring the mixture of sample and antigen for changes indicative of the presence of anti-Type V collagen in the sample. Another embodiment includes treating pulmonary diseases such as IPF by administering a therapeutically effective dose of epitopes of various collagens including Type V collagen. | 2011-01-27 |
20110020839 | METHODS AND COMPOSITIONS FOR DETECTING THE ACTIVATION STATE OF MULTIPLE PROTEINS IN SINGLE CELLS - The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides methods and compositions of screening for bioactive agents capable of coordinately modulating the activity of a plurality of proteins in single cells. The methods and compositions can be used to determine the protein activation profile of a cell for predicting or diagnosing a disease state, and for monitoring treatment of a disease state. | 2011-01-27 |