04th week of 2015 patent applcation highlights part 50 |
Patent application number | Title | Published |
20150025189 | Method Of Stabilizing Siloxanes Having Terminal Hydroxy Groups - Siloxanes having terminal hydroxy groups, and which have a content of cyclic siloxanes of not more than 5% by weight, are stabilized by addition of ammonia in gaseous form or as a solution in a protic or aprotic solvent or in the form of an ammonia-releasing compound in amounts of at least 0.01 ppm by weight and not more than 100 ppm by weight, calculated as ammonia and based on the total weight of the siloxanes having terminal hydroxy groups. Ammonia in gaseous form is preferably used. | 2015-01-22 |
20150025190 | FLAME RETARDANT PALLET - A flame retardant pallet that includes at least one structural component formed from a polymeric composite material. The polymeric composite material includes 35 weight percent (wt. %) to 78 wt. % of a polyolefin; 20 wt. % to 50 wt. % of a long glass fiber reinforcement; 0.5 wt. % to 3 wt. % of a coupling agent coupling the long glass fiber reinforcement to the polyolefin; and up to 25 wt. % of a flame retardant, wherein the wt. % values of the polymeric composite material are based on a total weight of the polymeric composite material and total to a value of 100 wt. %, and the polymeric composite material used to form the structural component has a specific strength of at least 55 kN·m/kg and a specific stiffness of at least 3500 kN·m/kg as tested according to ASTM D638-10 (tensile strength) and D790-00 (flex modulus), which were each divided by the specific gravity (determined through ASTM D792-08) to arrive at the given values. | 2015-01-22 |
20150025191 | Carbon Fiber Bundle and Manufacturing Method of the Same - The present invention relates to a carbon fiber bundle excellent in terms of adhesion to matrix resins and process handleability and less apt to suffer the shedding of the sizing agent in processing steps the carbon fiber bundle being a carbon fiber bundle having a sizing agent adherent to the surface thereof, characterized in that the carbon fiber bundle includes a plurality of carbon fibers and the sizing agent includes a copolyamide resin, the copolyamide resin having both a specific polyamide component and nylon-6 and/or nylon-66 as repeating units and having a melting point of 180° C. or lower, the copolyamide resin preferably having a melting point of 60 to 160° C., or a glass transition temperature of −20 to 50° C. | 2015-01-22 |
20150025192 | Black Polyimides and Synthesis Thereof - Black polyimides polymer and a method of synthesizing the same have been developed. The black polyimide polymer includes at least one acid monomer, at least one diamino monomer and a solvent-soluble black dye. The acid and diamino monomers having been reacting in a solvent under suitable conditions to form a polyimide precursor polymer. | 2015-01-22 |
20150025193 | POLYMERIZATION OF COMPOSITIONS COMPRISING A FARNESENE - Provided herein are polyfarnesenes such as farnesene homopolymers derived from a farnesene and farnesene interpolymers derived from a farnesene and at least a vinyl monomer; and the processes of making and using the polyfarnesenes. The farnesene homopolymer can be prepared by polymerizing the farnesene in the presence of a catalyst. In some embodiments, the farnesene is prepared from a sugar by using a microorganism. | 2015-01-22 |
20150025194 | METHOD FOR CONTROLLING SIZE DISTRIBUTION OF POLYMER PARTICLES DURING PREPARATION OF AQUEOUS POLYMER DISPERSION AND AQUEOUS POLYMER DISPERSION - The present disclosure relates to a method for controlling size distribution of formed polymer particles during preparation of aqueous polymer dispersion. The method comprises obtaining an aqueous polysaccharide solution, which comprises about 10 to 40 weight-% polysaccharide containing a free hydroxyl group, such as starch, and polymerising in the polysaccharide solution in the presence of a graft-linking, water-soluble redox system about 30 to 60 weight-% of at least one optionally substituted styrene, about 60 to 30 weight-% of at least one C1-C4-alkyl(meth)acrylate, and 0 to about 10 weight-% of other ethylenically unsaturated copolymerizable monomers. The size distribution of the formed polymer particles is controlled by adjusting viscosity of the polysaccharide solution before the polymerisation to a level less than about 20 mPas. The present disclosure relates also to an aqueous polymer dispersion having the D(99) value less than about 160 nm for polymer particles in the polymer dispersion and its use. | 2015-01-22 |
20150025195 | BIMODAL HIGH-DENSITY POLYETHYLENE RESINS AND COMPOSITIONS WITH IMPROVED PROPERTIES AND METHODS OF MAKING AND USING THE SAME - The present disclosure is related to bimodal high-density polyethylene polymer compositions with increased high melt strength and good processability comprising a base resin which has a density of about 945 kg/m | 2015-01-22 |
20150025196 | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF - The present invention relates to functionalized ploy(2-oxazoline) polymers, which are very suitable as a carrier and/or delivery vehicle (conjugate) of drugs, such as small therapeutic molecules and bio-pharmaceuticals. These polymers are characterized in that they comprise repeating units that are represented by the following formula —[N(R | 2015-01-22 |
20150025197 | Process For Preparing A Reinforced And Reactive Thermoplastic Composition, And this Composition - A process for preparing a reinforced and reactive thermoplastic composition having a continuous phase based on a thermoplastic polymer and dispersed therein is a discontinuous phase based on a reactive reinforcing agent that may be immiscible with the thermoplastic polymer is provided. A composition obtained by this process is also provided. The reinforcing agent is selected from the group consisting of epoxy resins, polyorganosiloxanes having SiH functional group(s), diisocyanates or polyisocyanates and mixtures thereof, comprises a grafting, a branching and/or a crosslinking, that are carried out in situ, by reactive compounding of these phases with a shear rate greater than 10 | 2015-01-22 |
20150025198 | THERMALLY STABLE BIURET AND ISOCYANURATE BASED SURFACE MODIFYING MACROMOLECULES AND USES THEREOF - The invention relates to surface modifying macromolecules (SMMs) having high degradation temperatures and their use in the manufacture of articles made from base polymers which require high temperature processing. The surface modifier is admixed with the base polymer to impart alcohol and water repellency properties. | 2015-01-22 |
20150025199 | CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER - This invention relates to novel catalyst compositions based on Ruthenium- or Osmium-based complex catalysts of the Grubbs-Hoveyda, Grela or Zhan type and specific co-catalysts comprising at least one vinyl group, pref. ethyl vinyl ether, and to a process for selectively hydrogenating nitrile rubbers in the presence of such catalyst compositions, preferably with a preceding metathesis step using the same complex catalyst as in the hydrogenation step. | 2015-01-22 |
20150025200 | COMPOSITION, POLYMER FILM, AND DISPLAY DEVICE - A composition including a diamine compound and a dianhydride compound, wherein the diamine compound includes a first diamine compound represented by Chemical Formula 1, | 2015-01-22 |
20150025201 | AMINES AND POLYMERIC PHENOLS AND USAGE THEREOF AS CURING AGENTS IN ONE COMPONENT EPOXY RESIN COMPOSITIONS - The disclosure relates to solving problems associated with conventional latent epoxy curing agents by providing a new class of latent epoxy curing agents. In particular, the disclosure relates to epoxy curing agents with improved storage stability and low use level (e.g., less than about 10 wt % relative to the epoxy compound) by forming solid solutions of certain classes of amines in polyphenolic resins. | 2015-01-22 |
20150025202 | PROCESS - The present invention relates to a process for the introduction of liquid feeds to a polymerisation process, and in particular provides a process for the introduction of a fresh feed selected from fresh comonomer and fresh inert hydrocarbon to a polymerisation reactor, which process comprises passing said fresh feed and a process stream comprising a first component selected from hydrogen, nitrogen and methane and a second component which is a monomer to a separator at a pressure of 0.4 MPa (4 bar) or less to produce a first stream comprising the majority of the first component and a second stream comprising the majority of the fresh feed and the majority of the second component, and passing the second stream to the polymerisation reactor. | 2015-01-22 |
20150025203 | POLYMERISATION PROCESS - The present invention relates to a polymerisation process, in particular to the polymerisation of olefins in a reactor system comprising two reactors in series, and most particularly provides a process for the polymerisation of monomer in at least first and second reactors operated in series, which process comprises contacting a first stream comprising vapour derived from the effluent withdrawn from the second reactor with a feed stream to the second reactor, said feed stream comprising effluent derived from the first reactor. | 2015-01-22 |
20150025204 | Hybrid Supported Metallocene Catalyst, Method for Preparing the Same, and Process for Preparing Polyolefin Using the Same - Provided are a hybrid supported metallocene catalyst, a method for preparing the same, and a process for preparing an olefin polymer using the same, and more particular, a hybrid supported metallocene catalyst characterized in that two kinds of metallocene compounds containing a new cyclopenta[b]fluorenyl transition metal compound are supported on an inorganic or organic porous carrier surface-treated with an ionic compound and a co-catalyst, a method for preparing the same, and a process for preparing an olefin polymer using the hybrid supported metallocene catalyst. | 2015-01-22 |
20150025205 | Metallocenes and Catalyst Compositions Derived Tehrefrom - This invention relates to a novel group 2, 3 or 4 transition metal metallocene catalyst compound that is asymmetric having two non-identical indenyl ligands with substitution at R | 2015-01-22 |
20150025206 | Metallocenes and Catalyst Compositions Derived Therefrom - This invention relates to a novel group 2, 3 or 4 transition metal metallocene catalyst compound having two indenyl ligands with identical substitution including, for example, cyclopropyl groups and substituted phenyl groups at the 2 and 4 positions of the catalyst, respectively, where the substituents are at the 3′ and 5′ positions of the phenyl groups. | 2015-01-22 |
20150025207 | Cyclopropyl Substituted Metallocene Catalysts - This invention relates to a novel group 2, 3 or 4 transition metal metallocene catalyst compound having at least one arenyl ligand substituted with: 1) a cyclopropyl group and, optionally, 2) at least one other group, such as a hydrocarbyl, a heteroatom or a heteroatom containing group. | 2015-01-22 |
20150025208 | Metallocenes and Catalyst Compositions Derived Therefrom - This invention relates to a novel group 4 transition metal metallocene catalyst compound that is asymmetric having two non-identical indenyl ligands with substitution at R | 2015-01-22 |
20150025209 | Substituted Metallocene Catalysts - This invention relates to novel bridged a hafnium transition metal metallocene catalyst compounds having two indenyl ligands substituted at the 4 positions with a C | 2015-01-22 |
20150025210 | Process Using Substituted Metallocene Catalysts and Products Therefrom - This invention relates to a process to produce propylene polymer using a bridged hafnium transition metal metallocene catalyst compounds having two indenyl ligands substituted at the 4 positions with a C | 2015-01-22 |
20150025211 | CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS - A catalyst system comprising the product obtained by contacting (a) a solid catalyst component containing Mg, Ti, halogen and at least an electron donor compound selected from phenylene aromatic diesters of a specific formula
| 2015-01-22 |
20150025212 | NOVEL ORGANOMETALLIC CATALYSTS - The present invention refers to novel ruthenium- and osmium-based catalysts for olefin metathesis reactions, particularly to catalysts having stereoselective properties. Z-selectivity is obtained by utilising two mono-anionic ligands of very different steric requirement. In olefin metathesis reactions these catalysts selectively provide the Z-isomer of disubstituted olefinic products even in presence of air or of acids. | 2015-01-22 |
20150025213 | CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME - Here is provided a charge control resin which is prompt in charge rising up, excellent in electrostatic charging propensity and easy in manufacturing. This charge control resin contains a polymer as an active ingredient having a constituent unit represented by following Formula (1) | 2015-01-22 |
20150025214 | PROCESSES FOR THE REMOVAL OF RUBBER FROM NON-HEVEA PLANTS - Provided herein are organic solvent-based processes for the removal of rubber from non- | 2015-01-22 |
20150025215 | Fluorene derivatives and lens using the same - Disclosed herein are fluorene derivatives and a lens using the same. | 2015-01-22 |
20150025216 | PRODUCTION METHOD FOR ALIPHATIC POLYESTER - To efficiently produce an aliphatic polyester and to improve the thermal stability of the resulting aliphatic polyester. | 2015-01-22 |
20150025217 | YIELD OPTIMIZATION OF POLYCARBONATE POLYOLS - Embodiments of the invention provide for methods of producing a polycarbonate polyol. The method includes charging a vessel with butanediol, charging the vessel with a polymerization catalyst, and adding to the vessel dimethyl carbonate at a rate of at least 2.0 g of DMC per minute per kg of BDO to produce polycarbonate polyol at a polycarbonate polyol yield of at least 80% of a theoretical yield. | 2015-01-22 |
20150025218 | POLYGLYCOLIC ACID AND COPOLYMERS THEREOF FROM C1 FEEDSTOCKS - A method of preparing a poly(glycolic acid) (PGA) from the C1 feedstocks carbon monoxide and formaldehyde or its equivalent. By controlling the comonomer feed ratios and the polymerization temperatures, high quality PGA can be prepared. The method is extended to copolymers of PGA where alkylene oxides or cyclic ether comonomers are included into the polymerization mixture with the C1 monomers to yield polyester-ether thermoplastics. | 2015-01-22 |
20150025219 | CYCLIC PENTADEPSIPEPTIDES AND MICROORGANISM OF FUSARIUM STRAIN PRODUCING THE SAME - Disclosed is a | 2015-01-22 |
20150025220 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY - The invention provides a compound of formula I: | 2015-01-22 |
20150025221 | Skin Permeating and Cell Entering (SPACE) Peptides and Methods of Use Thereof - The present disclosure provides peptides and peptide compositions, which facilitate the delivery of an active agent or an active agent carrier wherein the compositions are capable of penetrating the stratum corneum (SC) and/or the cellular membranes of viable cells. | 2015-01-22 |
20150025222 | Substituted Anthraquinone Dyes for Cellular Stains and Enzyme Detection - The invention discloses new substituted anthraquinone dyes that may be useful as cellular stains. In some aspect of the invention, the nuclear stains are useful for staining the nuclei of dead or fixed cells. Another aspect of the invention relates to substituted anthraquinone dyes comprising an enzyme substrate moiety that is transformable or cleavable by an enzyme such that the transformation or cleavage of the substrate moiety causes a detectable change in the functionality or spectral properties of the dye. | 2015-01-22 |
20150025223 | System and Method for Producing Interleukin Receptor Antagonist (IRA) - The present invention relates to a system and method for producing high levels of autologous IL-1RA cytokine, comprising: a blood collection vessel ( | 2015-01-22 |
20150025224 | ANTAGONISTS OF NEUROPILIN RECEPTOR FUNCTION AND USE THEREOF - The present invention relates to antagonists of neuropilin receptor function and use thereof in the treatment of cancer, particularly metastatic cancer, and angiogenic diseases. | 2015-01-22 |
20150025225 | MONOCLONAL ANTIBODY AGAINST EL WHICH INHIBITS ENZYME ACTIVITY OF EL - Provided is a monoclonal antibody or a fragment thereof that selectively inhibits enzyme activity of EL and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome. | 2015-01-22 |
20150025226 | MONOCLONAL ANTIBODY FOR ANALYZING HIGH-MOLECULAR WEIGHT ADIPONECTIN AND UTILIZATION OF SAME - A monoclonal antibody that does not show a crossreactivity with middle-molecular weight (MMW) adiponectin and specifically reacts with high-molecular weight (HMW) adiponectin alone is disclosed. The monoclonal antibody of the present invention can be produced by using HMW adiponectin as an antigen. According to the monoclonal antibody of the present invention, a convenient, high-accurate, and versatile reagent for analyzing HMW adiponectin can be provided. | 2015-01-22 |
20150025227 | IGG FC FRAGMENT FOR A DRUG CARRIER AND METHOD FOR THE PREPARATION THEREOF - Disclosed is an IgG Fc fragment useful as a drug carrier. A recombinant vector expressing the IgG Fc fragment, a transformant transformed with the recombinant vector, and a method of preparing an IgG Fc fragment are disclosed. When conjugated to a certain drug, the IgG Fc fragment improves the in vivo duration of action of the drug and minimizes the in vivo activity reduction of the drug. | 2015-01-22 |
20150025228 | IGG FC FRAGMENT FOR A DRUG CARRIER AND METHOD FOR THE PREPARATION THEREOF - Disclosed is an IgG Fc fragment useful as a drug carrier. A recombinant vector expressing the IgG Fc fragment, a transformant transformed with the recombinant vector, and a method of preparing an IgG Fc fragment are disclosed. When conjugated to a certain drug, the IgG Fc fragment improves the in vivo duration of action of the drug and minimizes the in vivo activity reduction of the drug. | 2015-01-22 |
20150025229 | PROCESS FOR SEPARATING BIOMASS COMPONENTS - The present invention provides a process and System for Separation of biomass components into individual components such as cellulose, hemicellulose and lignin. The present invention provides a process for separating lignin in its native form. The cellulose obtained by the process of the present invention is highly reactive for saccharification. | 2015-01-22 |
20150025230 | Single Nucleotide Polymorphisms in BRCA1 and Cancer Risk - The invention provides methods for identifying mutations, such as single nucleotide polymorphisms (SNPs), within breast and ovarian cancer associated genes that modify the binding efficacy of microRNAs (miRNAs). In a preferred embodiment, methods of the invention identify a SNP that decreases expression of the BRCA1 gene by increasing or decreasing the binding efficacy of at least one miRNA. Alteration of miRNA binding to BRCA1 by the introduction of SNPs within miRNA binding sites modulates or decreases BRCA1 expression, ultimately leading to the unregulated cell proliferation of a breast or ovarian cancer cells. | 2015-01-22 |
20150025231 | COMPOSITIONS AND METHODS FOR MODULATION OF IKBKAP SPLICING - The present disclosure provides compounds comprising oligonucleotides complementary to a portion of the IKBKAP gene. Certain such compounds are useful for hybridizing to a portion of the IKBKAP gene, including but not limited to a portion of the IKBKAP gene in a cell. In certain embodiments, such hybridization results in modulation of splicing of the IKBKAP gene. In certain embodiments, the IKBKAP gene includes a mutation that results in defective splicing and a truncated IKAP protein. In certain embodiments, hybridization of oligonucleotides complementary to a portion of the IKBKAP gene results in a decrease in the amount of defective splicing and truncated IKAP protein. In certain embodiments, hybridization of oligonucleotides complementary to a portion of the IKBKAP gene results in an increase in the amount of normal splicing and functional, full-length IKAP protein. In certain embodiments, oligonucleotides are used to treat Familial Dysautonomia. | 2015-01-22 |
20150025232 | HEPTAMER-TYPE SMALL GUIDE NUCLEIC ACIDS INDUCING APOPTOSIS OF HUMAN LEUKEMIA CELLS - There is provided a heptamer-type small guide nucleic acid that comprises any of the 7-base sequences of SEQ ID NOS: 1 to 15, and induces apoptosis of human leukemia cells. A leukemia therapeutic agent containing the heptamer-type small guide nucleic acid as an active ingredient is also provided. The novel heptamer-type sg nucleic acid can induce apoptosis of human leukemia cells. | 2015-01-22 |
20150025233 | USE OF LIPID CONJUGATES IN THE TREATMENT OF DISEASES - This invention provides compounds represented by the structure of the general formula (A): | 2015-01-22 |
20150025234 | GANGLIOSIDE COMPOSITIONS - The invention provides novel gangliosides and mixtures of novel gangliosides, and drug products containing the same. The invention also provides cells induced to over-express one or more gangliosides. The invention further provides methods for production of gangliosides, e.g., GM1, from cells in culture using, for example, bone marrow cells and neuroblastoma cells. Methods include the treatment of cells with neural induction media and chloroquine, or chloroquine alone in the case of, e.g., human bone marrow cells, neuraminidase or glucosamine, to induce the production of gangliosides, e.g., GM1, in the cells. Also provided are methods of long-term, high density culturing of cells without passaging to produce gangliosides, e.g., GM1. Methods of quantifying gangliosides, e.g., GM1 in cell culture are also provided. | 2015-01-22 |
20150025235 | Benzamide Compounds and Related Methods of Use - Benzamide compounds and derivatives thereof, as can be used for selective inhibition of the SIRT2 enzyme and/or therapeutic use in the treatment of Huntington's disease. | 2015-01-22 |
20150025236 | PROCESS FOR THE PREPARATION OF STABLE CRYSTALLINE FORM-I OF LINEZOLID, SUBSTANTIALLY FREE OF RESIDUAL SOLVENT - The invention relates to a substantially pure linezolid hydroxide having R-isomer content more than about 99.9% relative to its S-isomer. Further aspect of invention provides the ambient moisture condition, which is critical for enantiomeric pure linezolid hydroxide. The obtained substantially enantiomerically pure linezolid hydroxide compound of formula-II can be subsequently converted into the linezolid compound of formula-I, having S-isomer content more than 99.9% relative to R-isomer. Further the invention provides an improved process for preparation of enantiomeric pure linezolid Form-I, wherein linezolid Form-I having the purity more than 99.9% relative to any other known polymorphic form of linezolid. The obtained enantiomeric pure linezolid Form-I can be subsequently converted into the other known polymorphic forms linezolid. The invention also provides stable and substantially solvent-free crystal of Form-I of linezolid. | 2015-01-22 |
20150025237 | Methods and Compounds Useful in the Synthesis of Orexin-2 Receptor Antagonists - The present disclosure provides compounds and methods that are useful for the preparation of compounds useful as orexin-2 receptor antagonists. | 2015-01-22 |
20150025238 | ARYLALKYL ESTERS OF 4-AMINO-6-(SUBSTITUTED PHENYL)-PICOLINATES AND 6-AMINO-2-(SUBSTITUTED PHENYL)-PYRIMIDINECARBOXYLATES AND THEIR USE AS SELECTIVE HERBICIDES FOR CROPS - Arylalkyl esters of 4-aminopicolinic acids and 6-amino-4-pyrimidinecarboxylates are herbicides for control of weeds especially those species common to rice and wheat cropping systems and in pasture management programs. | 2015-01-22 |
20150025239 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME - The present invention relates to a novel organic electroluminescent compound and an organic electroluminescent device comprising the same. The organic electroluminescent compound according to the present invention is better in luminous efficiency and lifespan characteristics compared to conventional materials. Using the compounds of the present invention, it is possible to manufacture an OLED device with a long operational lifespan. In addition, the compounds can improve the power efficiency of the device to reduce overall power consumption. | 2015-01-22 |
20150025240 | SALTS OF PRODRUGS OF PIPERAZINE AND SUBSTITUTED PIPERIDINE ANTIVIRAL AGENTS - This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection. | 2015-01-22 |
20150025241 | METHOD FOR PREPARING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE - The present invention relates to an improved method for preparing dipeptidyl peptidase-IV inhibitor and intermediate. The present invention is able to reduce preparation costs by using low cost reagents on reaction and is able to be used in mass production by improving yield. | 2015-01-22 |
20150025242 | APIXABAN PREPARATION PROCESS - Process for the preparation of apixaban and intermediates useful for the preparation thereof. | 2015-01-22 |
20150025243 | FORMULATIONS CONTAINING CLOPIDOGREL AND SULFOALKYL ETHER CYCLODEXTRIN AND METHODS OF USE - The present invention provides compositions containing clopidogrel, present as a free base or a pharmaceutically acceptable salt thereof, and sulfoalkyl ether cyclodextrin (SAE-CD). The compositions can be liquid, suspension or solid compositions. They can be adapted for oral, peroral or parenteral administration. The SAE-CD serves to aid in dissolution and stabilization of the clopidogrel in aqueous media. The stability of clopidogrel against hydrolytic degradation, thermal degradation, and photolytic degradation are improved. SAE-CD provides improved results over other cyclodextrin derivatives. The SAE-CD-containing composition of clopidogrel can be provided in liquid form, solid form or as a reconstitutable powder. Both ready-to-use and concentrated liquid compositions can be prepared. The liquid composition is optionally available as a clear solution. The compositions herein can be administered perorally or parenterally and provide substantial pharmacokinetic, pharmacodynamic and/or therapeutic advantages over a tablet composition administered perorally and excluding SAE-CD. | 2015-01-22 |
20150025244 | Process for Manufacturing a Naphthyridine Derivative - The invention relates to a process and synthetic intermediates that can be used for manufacturing the compound of formula (1-6) which is a synthetic intermediate useful in the preparation of antibiotic compounds. | 2015-01-22 |
20150025245 | PROCESS FOR PREPARING CHLOROAMINES - The present application relates to a process for preparing chloroamines which can be used as precursors for syntheses of fine chemicals and active ingredients from pharmaceuticals and/or agriculture, by reaction of secondary amines of the formula (II) with chlorine gas in the presence of an aqueous alkali metal or alkaline earth metal oxide base. | 2015-01-22 |
20150025246 | PROCESS FOR PREPARATION OF ROFLUMILAST - The present invention provides novel processes for the preparation of N-substituted benzamides having the formula (VIc). In some embodiments, the invention provides a process for preparation of roflumilast and other pharmaceutically active species. Novel compounds, including intermediates for the synthesis of roflumilast, are also provided. | 2015-01-22 |
20150025247 | ESTERS OF O-SUBSTITUTED HYDROXY CARBOXYLIC ACIDS AND PREPARATIONS THEREOF - Esters of O-substituted hydroxy carboxylic acids are provided having Formula 1, or 2, or both Formulas 1 and 2: | 2015-01-22 |
20150025248 | RADIOTRACER PRECURSOR BANI FOR IMAGING OF HYPOXIC TISSUE, RADIOTRACER, AND METHOD FOR PREPARING THE SAME - The present invention relates to a radiotracer precursor for imaging of hypoxic tissues, a radiotracer and a method for preparing the same. The radiotracer precursor, BANI, includes a nitroimidazole functional group with a feature of retention in hypoxic tissues and a bifunctional ligand able to complex with radioisotopes. Thus BANI can be used to produce radiotracers retained in hypoxic tissues and the radiotracers are applied to medical imaging of malignant tumor with hypoxic layer. | 2015-01-22 |
20150025249 | PROCESS FOR THE PREPARATION OF PROPIONIC ACID DERIVATIVES - The invention relates to a process for the preparation of a compound of formula (I) | 2015-01-22 |
20150025250 | CYSTEINE PROTEASE INHIBITORS - Compounds of the formula I | 2015-01-22 |
20150025251 | CHROMAN DERIVATIVE - The invention provides a chroman derivative represented by the following Formula (I) that enables the production of an SMTP compound having a desired structure: | 2015-01-22 |
20150025252 | PROCESS FOR THE PERPARATION OF SUNITINIB AND ITS ACID ADDITION SALTS THEREOF - The present invention relates to an improved process for the preparation of Sunitinb. The process involves the activation of 5-((Z)-(5-fluoro-2-oxoindolin-3-ylidene) methyl)-2,4-dimethyl-1H-pyrrole-3carboxylic acid to corresponding suitable carboxylic acid activating group. The present invention also relates to novel acid addition salts of Sunitinb and preparation thereof. | 2015-01-22 |
20150025253 | PESTICIDAL ARYLPYRROLIDINES - Arylpyrrolidines of formula (I): | 2015-01-22 |
20150025254 | PRODUCTION METHOD FOR CYCLOPENTANONE DERIVATIVE, INTERMEDIATE COMPOUND, AND PRODUCTION METHOD FOR INTERMEDIATE COMPOUND - The present invention is a production method for a compound represented by the following general formula (V), the method comprising a step of obtaining a compound represented by the following general formula (II) by reacting a compound represented by the following general formula (I) with an acid: | 2015-01-22 |
20150025255 | PROCESS FOR PREPARING SYNTHETIC PROSTACYCLINS - The presently disclosed subject matter provides methods of preparing synthetic prostacyclin analogues, including Beraprost, either as racemic mixtures or as single stereoisomers. Also provided are novel synthetic intermediates for use in these methods. | 2015-01-22 |
20150025256 | Purification of 5-Hydroxymethylfurfural (HMF) by Crystallization - This invention relates to an efficient procedure for purifying HMF by crystallization at low temperature from an organic solvent. | 2015-01-22 |
20150025257 | DOCOSAHEXAENOYL ETHANOLAMIDES - The invention describes novel mono or dihydroxy docosahexaenoic acid (DHA) analogues, their preparation, isolation, identification, purification and uses thereof. | 2015-01-22 |
20150025258 | OIL SOLUBLE HYDROGEN SULFIDE SCAVENGER - The concentration of hydrogen sulfide in a hydrocarbon can be mitigated by intruding therein a zinc carboxylate oxo complex composition prepared by reacting particulate zinc oxide with a mixture of two or more carboxylic acids wherein the zinc carboxylate oxo complex composition is soluble in hydrocarbons. Useful acids useful include acetic acid, oleic acid, isobutyric acid, lineoleic acid, cekanoic acid, and neodecanoic acid. | 2015-01-22 |
20150025259 | PROCESS FOR TREATING REACTION SOLUTION CONTAINING LONG CHAIN DICARBOXYLATE - Disclosed is a process for treating a reaction solution containing a long chain dicarboxylate. The process is characterized by comprising: acidifying a reaction solution so as to convert the long chain dicarboxylate into a long chain dicarboxylic acid, adding an extractant so as to extract the resulting long chain dicarboxylic acid, separating the phase rich in the long chain dicarboxylic acid, and further separating the long chain dicarboxylic acid. The process of the present invention has the following advantages: 1) the processing route is simple, the operation time is short, less equipment is required, and the production efficiency is high; 2) product yield is high; 3) product quality is good, purity in the resulting products is high, and the color is lighter; and 4) no active carbon is consumed and the solvent can be recycled, thereby saving resources and being environmentally friendly. | 2015-01-22 |
20150025260 | PROCESS FOR THE PREPARATION OF A GRANULAR MICROBIAL BIOMASS AND ISOLATION OF A COMPOUND THEREFROM - A process for the isolation of desired compound(s) from a microbial biomass is disclosed, wherein the microbial biomass (which, if necessary, is pretreated to give a dry matter content of from 25 to 80%) is granulated (e.g. by extrusion) and then dried to a dry matter content of at least 80%. The granulation of the biomass to granules significantly eases subsequent drying of the biomass (which can be stored as dried granules) and gives higher yields on extraction of the compound(s). | 2015-01-22 |
20150025261 | PROCESS FOR SURFACE MODIFICATION OF PARTICULATE SOLIDS - Improved utilization of organosilicon compounds in hydrophobicizing finely divided particulate solids is accomplished by metering a partial amount of unreacted solids with organosilicon containing offgases derived from admixing and reacting a major portion of solids with organosilicon compounds and admixing the offgas-treated solids with the major portion of solids to be treated. | 2015-01-22 |
20150025262 | BIS(ARYL)ACETAL COMPOUNDS - A bis(aryl)acetal has the formula | 2015-01-22 |
20150025263 | 3,4-DIALKYLBIPHENYLDICARBOXYLIC ACID COMPOUND, 3,4-DICARBOALKOXYBIPHENYL-3',4'-DICARBOXYLIC ACID AND CORRESPONDING ACID ANHYDRIDES, AND PROCESSES FOR PRODUCING THESE COMPOUNDS - 3,4-Dicarboalkoxybiphenyl-3′,4′-dicarboxylic acid represented by the general formula (1): | 2015-01-22 |
20150025264 | METHOD FOR PRODUCING HYDROGEN OR HEAVY HYDROGENS, METHOD FOR PRODUCING HYDROGENATED (PROTIATED, DEUTERATED OR TRITIATED) ORGANIC COMPOUND, METHOD FOR HYDROGENATING (PROTIATING, DEUTERATING OR TRITIATING) ORGANIC COMPOUND, METHOD FOR DEHALOGENATING ORGANIC COMPOUND HAVING HALOGEN, AND BALL FOR USE IN MECHANOCHEMICAL REACTION - Objects are to provide efficient methods for producing hydrogen or heavy hydrogens and for hydrogenating (protiating, deuterating or tritiating) an organic compound, and to provide an equipment and the like used therefor. A method for producing hydrogen or heavy hydrogens, containing subjecting water or heavy water to mechanochemical reaction in the presence of a catalyst metal, in which an energy density of a rotational acceleration of 75 G or more is applied to water or heavy water for 25 minutes or more, a method for producing a hydrogenated (protiated, deuterated or tritiated) organic compound, a method for hydrogenating (protiating, deuterating or tritiating) an organic compound, a method for dehalogenating an organic compound having halogen, and a ball for mechanochemical reaction are provided. | 2015-01-22 |
20150025265 | CRYSTALLINE INGENOL MEBUTATE - The present invention relates to a novel crystalline form of ingenol mebutate, methods of preparation thereof, and to its use. More specifically, the invention relates to the conversion of amorphous ingenol mebutate (ingenol-3-angelate, PEP005) to a crystalline form, which was characterized by single crystal X-Ray crystallography (XRC), attenuated total reflectance Fourier transform infrared (FTIR-ATR) spectroscopy and Differential Scanning calorimetry (DSC). | 2015-01-22 |
20150025266 | SYNTHESIS OF HIGH CALORIC FUELS AND CHEMICALS - In one embodiment, the present application discloses methods to selectively synthesize higher alcohols and hydrocarbons useful as fuels and industrial chemicals from syngas and biomass. Ketene and ketonization chemistry along with hydrogenation reactions are used to synthesize fuels and chemicals. In another embodiment, ketene used to form fuels and chemicals may be manufactured from acetic acid which in turn can be synthesized from synthesis gas which is produced from coal, biomass, natural gas, etc. | 2015-01-22 |
20150025267 | METAL POWDERDOUS CATALYST COMPRISING A FE-ALLOY - The present invention is related to a new metal powder catalytic system (catalyst) comprising a Fe-alloy as a carrier, its production and its use in hydrogenation processes. | 2015-01-22 |
20150025268 | PROCESS FOR THE PREPARATION OF POLYISOCYANATES AND USE THEREOF - The invention relates to a process for isocyanate modification which includes reacting a) at least one organic isocyanate having an NCO functionality greater than or equal to 1, b) a catalyst comprising at least one phosphonium salt comprising at least one cycloalkyl substituent bonded directly to a P atom of a phosphonium cation, c) optionally a solvent, and d) optionally additives. The present invention also relates to a catalyst for isocyanate modification comprising at least one phosphonium salt comprising at least one cycloalkyl substituent bonded directly to a P atom of a phosphonium cation. | 2015-01-22 |
20150025269 | PROCESS FOR PREPARATION OF ALKYNYL CARBOXYLIC ACIDS - The invention provides a simple, efficient, environmental friendly catalytic system for the direct carboxylation reaction using CO | 2015-01-22 |
20150025270 | PROCESS FOR PRODUCING ACETIC ACID - A production process of acetic acid according to the present invention inhibits concentration of hydrogen iodide and improves a liquid-liquid separation of an overhead from a distillation column. Acetic acid is produced by distilling a mixture containing hydrogen iodide, water, acetic acid and methyl acetate in a first distillation column ( | 2015-01-22 |
20150025271 | METHOD FOR PRODUCING POLYOXYALKYLENE ALKYL ETHER CARBOXYLIC ACID OR SALT THEREOF - A method for producing polyoxyalkylene alkyl ether carboxylic acid or a salt thereof includes an oxidation reaction process of oxidizing polyoxyalkylene alkyl ether with oxygen by supplying an oxygen-containing gas to a suspension or a solution that has a depth of 200 mm or more and includes polyoxyalkylene alkyl ether. In the oxidation reaction process, a supply rate of the oxygen-containing gas is reduced in a period in which the conversion is greater than or equal to 50% and less than 70%. | 2015-01-22 |
20150025272 | PROCESS FOR PREPARING MODIFIED V-TI-P CATALYSTS FOR SYNTHESIS OF 2,3-UNSATURATED CARBOXYLIC ACIDS - The invention relates to a catalyst composition comprising a mixed oxide of vanadium, titanium, and phosphorus modified with alkali metal. The titanium component is derived from a water-soluble, redox-active organo-titanium compound. The catalyst composition is highly effective at facilitating the vapor-phase condensation of formaldehyde with acetic acid to generate acrylic acid, particularly using an industrially relevant aqueous liquid feed. | 2015-01-22 |
20150025273 | PROCESS FOR THE SYNTHESIS OF UREA COMPRISING A PASSIVATION STREAM AT THE STRIPPER BOTTOM - A process for the direct synthesis of urea from ammonia and carbon dioxide with increased corrosion resistance, comprising, in the high-pressure synthesis section, a reaction step in a vertical reactor fed with at least one stream of fresh carbon dioxide containing a passivating agent and a decomposition-stripping step of the non-converted reagents, wherein the gas-liquid mixture collected at the head of the reactor is separated into a gaseous stream and a liquid stream fed to the tail and head of the stripper, respectively. | 2015-01-22 |
20150025274 | PROCESSES FOR THE PREPARATION OF (R)-2-ACETAMIDO-N-BENZYL-3-METHOXYPROPIONAMIDE AND INTERMEDIATES THEREOF - This invention relates to processes for the preparation of (R)-2-acetamido-N-benzyl-3-methoxypropionamide (I) and intermediates thereof. Formula (I). | 2015-01-22 |
20150025275 | Iodination Process for the Preparation of 3, 5-Disubstituted-2, 4, 6-Triiodo Aromatic Amines Compounds - The invention discloses a improved process for the preparation of 3,5-disubstituted-2,4,6-triiodo aromatic amines of formula (II), wherein R1 and R2 are defined as herein. The compounds of formula (II) are the key intermediates for the synthesis of a series of non-ionic contrast agents such as Iopamidol, Iohexol and Iodixanol. The process comprises reacting chlorine-free iodinating reagents with 3,5-disubstituted-2,4,6-triiodo aromatic amines to obtain 3,5-disubstituted-2,4,6-triiodo aromatic amines of formula (II), wherein the molar yield of the iodination reaction can reach to 89%. | 2015-01-22 |
20150025276 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND - A method for producing an organolithium compound includes the step of reacting an aromatic compound or a halogenated unsaturated aliphatic compound and a lithiating agent in the presence of a coordinating compound containing three or more elements having a coordinating ability in a molecule, at least one thereof being a nitrogen element, or a coordinating compound containing three or more oxygen elements having a coordinating ability in a molecule, at least one of the groups containing the oxygen elements having a coordinating ability being a tertiary alkoxy group, at a temperature of −40° C. to 40° C. | 2015-01-22 |
20150025277 | Two-Step System And Method For The Production Of Methyl Isobutyl Ketone - Embodiments of the present invention describe systems and methods for production of methyl isobutyl ketone (MIBK) from acetone and hydrogen in a two-step process. In a first step, acetone is converted to a product stream containing mesityl oxide (MO) at a temperature in the range of about 0-120° C. and a pressure in the range of about 1-3 atm. The composition of the product stream from the first reaction step is adjusted so that the resulting stream can undergo a favorable liquid-liquid separation in a decanter, and an MO rich product stream can be recovered. The composition of the feed to the decanter is controlled by choosing the number of reactor stages for the first reaction step and their operating temperatures, and/or by recycling some MIBK to the decanter feed. The method does not require a substantially complete conversion of acetone in the first reaction step, nor does it require a removal of DAA from the product of the first reaction step by separation. | 2015-01-22 |
20150025278 | AROMATIC POLYACETALS AND ARTICLES COMPRISING THEM - A polymer includes repeat units having the structure | 2015-01-22 |
20150025279 | PROCESS FOR PRODUCING DODECANE-1,12-DIOL BY REDUCTION OF LAURYL LACTONE PRODUCED FROM THE OXIDATION OF CYCLODODECANONE - A process for synthesizing dodecane-1,12-diol, and by-products thereof, by the reduction of lauryl lactone produced from the oxidation of cyclododecanone. | 2015-01-22 |
20150025280 | LIGANDS FOR RHODIUM CATALYZED REDUCTIVE CARBONYLATION OF ALCOHOLS - A catalytic system for reductive carbonylation of an alcohol that includes a rhodium complex, an iodide-containing catalyst promoter, and a supporting phosphorus-containing bidentate ligand for the rhodium complex containing at least one aromatic substituent covalently attached to at least one phosphorus of the supporting phosphorus-containing bidentate ligand in an ortho position with an alkoxy substituent or an aryloxy substituent. | 2015-01-22 |
20150025281 | Process for Producing Ethanol Using Hydrogenation Catalysts - The present invention relates to catalysts, to processes for making catalysts and to chemical processes employing such catalysts. The catalysts are preferably used for converting acetic acid to ethanol. The catalyst comprises a precious metal and one or more active metals on a modified support. The modified support may comprise cobalt tungstate. | 2015-01-22 |
20150025282 | Process to make 1,1,2,3-Tetrachloropropene - Disclosed is a process for the synthesis of 1,1,2,3-tetrachloropropene (HCC-1230xa) using 1,1,3-trichloropropene (HCC-1240za) and/or 3,3,3-trichloropropene (HCC-1240zf) and Cl | 2015-01-22 |
20150025283 | Process and Catalyst for C9+ Aromatics Conversion - The invention is directed to a multimetallic catalyst and its use in a reactor system in a C9+ aromatics conversion process in order to reduce the saturation of aromatic species, reduce the production of C6+ non-aromatics byproducts, and achieve higher benzene purity. The multimetallic catalyst exhibits improved selectivity towards aromatic hydrocarbons in comparison to a traditional Pt/ZSM-5 catalyst and comprises ZSM-5, a Group 6-10 metal, and an additional metal not in Group 6-10. The C9+ aromatics conversion reactor system comprises a top bed containing the multimetallic catalyst for dealkylation of ethyl and propyl side chains, a second bed containing a catalyst comprising a hydrogenation component for transalkylation, and an optional third bed containing a catalyst without a hydrogenation component to convert non-aromatic hydrocarbons to gas products. | 2015-01-22 |
20150025284 | OXYGENATE REMOVAL FROM LIGHT HYDROCARBON PROCESSING - Processes for eliminating water and oxygenates from a light hydrocarbon processing system, wherein oxygenates are removed from a light hydrocarbon stream by adsorption of the oxygenates on a primary oxygenate adsorption unit to provide a deoxygenated hydrocarbon stream, the primary oxygenate adsorption unit is regenerated via a first regenerant stream to provide an oxygenated first regenerant stream, the oxygenated first regenerant stream is deoxygenated via a secondary oxygenate adsorption unit, and the secondary oxygenate adsorption unit is regenerated via a second regenerant stream to provide an oxygenated second regenerant stream for permanent removal from the system. | 2015-01-22 |
20150025285 | REGENERATION OF OLEFIN TREATING ADSORBENTS FOR REMOVAL OF OXYGENATE CONTAMINANTS - Processes for eliminating oxygenates and water from a light hydrocarbon processing system, wherein oxygenates are removed from a light hydrocarbon stream by adsorption of the oxygenates on an oxygenate adsorption unit to provide a deoxygenated hydrocarbon stream, the oxygenate adsorption unit is regenerated via a regenerant stream to provide an oxygenated regenerant stream comprising the oxygenates, and the oxygenated regenerant stream is subjected to hydro-deoxygenation to convert the oxygenates into paraffins and water, wherein the water may also be permanently removed from the system. | 2015-01-22 |
20150025286 | Production of Monoalkyl Aromatic Compounds - The present disclosure relates to a process for production of a monoalkyl aromatic compound by alkylation of alkylatable aromatic compounds with an alkylating agent in a reactor comprising at least a first and a second series-connected alkylation reaction zones and a cooler disposed between the first and the second series-connected alkylation reaction zones. The process comprising a step of cooling at least a portion of an effluent withdrawn from the first alkylation reaction zone before being introduced into the second alkylation reaction zone. | 2015-01-22 |
20150025287 | UZM-39 ALUMINOSILICATE ZEOLITE - A new family of coherently grown composites of TUN and IMF zeotypes have been synthesized. These zeolites are represented by the empirical formula. | 2015-01-22 |
20150025288 | Process for the Dehydration of Aqueous Bio-Derived Terminal Alcohols to Terminal Alkenes - A method and apparatus for dehydrating bio-1-alcohols to bio-1-alkenes with high selectivity. The bio-1-alkenes are useful in preparing high flashpoint diesel and jet biofuels which are useful to civilian and military applications. Furthermore, the bio-1-alkenes may be converted to biolubricants useful in the transporation sector and other areas requiring high purity/thermally stable lubricants. | 2015-01-22 |