03rd week of 2009 patent applcation highlights part 50 |
Patent application number | Title | Published |
20090018343 | Fluorous Oxazolidinone Chiral Auxiliary Compounds and Methods of Manufacture - The present invention relates generally to perfluoroalkyl chiral auxiliary compounds and methods of manufacture. These compounds have the functionality to effectively support the synthesis of chiral compounds in single reactions, high-throughput parallel reactions, or combinatorial reactions The invention relates to two oxazolidinone chiral auxiliaries (1) and (2): wherein R | 2009-01-15 |
20090018344 | PROCESS FOR THE PREPARATION OF CANDESARTAN CILEXETIL - The invention relates to process for the preparation of Candesartan cilexetil. More particularly, it relates to the preparation of pure candesartan cilexetil by the deprotection of Trityl candesartan cilexetil with inorganic acids. | 2009-01-15 |
20090018345 | PYRAZOLE-1-CARBOXYLATE DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND PROCESS FOR THE PRODUCTION OF PYRAZOLE DERIVATIVES - Disclosed are pyrazole-1-carboxylate derivatives of the general formula (1), | 2009-01-15 |
20090018346 | Amorphous Form Of Darifenacin Hydrobromide And Processes For The Preparation Thereof - The present invention relates to amorphous form darifenacin hydrobromide and processes therefor. In addition, the present invention relates to compositions comprising amorphous form darifenacin hydrobromide. | 2009-01-15 |
20090018347 | PROCESS FOR PURIFYING REMOVAL OF ACRYLIC ACID, METHACRYLIC ACID, N-VINYLPYRROLIDONE OR P-XYLENE CRYSTALS FROM THEIR SUSPENSION IN MOTHER LIQUOR - A process for purifying removal of acrylic acid, methacrylic acid, N-vinylpyrrolidone or p-xylene crystals from their suspension in mother liquor by means of a wash column with forced transport, whose shell of the process chamber is a metal wall, the wash column additionally being enveloped by a thermal insulation material having a water vapor barrier and a specific heat flow of >0.1 W/m | 2009-01-15 |
20090018348 | Heterocyclic Fused Selenophene Monomers - A heterocyclic fused selenophenes and a method of making a heterocyclic fused selenophenes of formula (1): | 2009-01-15 |
20090018349 | PROCESS FOR PRODUCING 2, 3, 3', 4', -BIPHENYLTETRACARBOXYLIC DIANHYDRIDE - 2,3,3′,4′-biphenyltetracarboxylic acid is heat-dehydrated in a molten state at a temperature not lower than 200° C. in a flow of an inert gas in a reactor | 2009-01-15 |
20090018350 | NOVEL FLUORINE-CONTAINING ETHER COMPOUND - A fluorine-containing ether compound with a fluorine content increased, the fluorine content being enhanced by fluorinating a polymer including a repeating unit represented by the following Formula (I): | 2009-01-15 |
20090018351 | PREPARATION OF ESCITALOPRAM - The present invention relates to a process for preparing enantiomerically enriched citalopram via methylating enantiomerically enriched didesmethylcitalopram, which is prepared by directly resolving racemic didesmethylcitalopram using a chiral acid. | 2009-01-15 |
20090018352 | Method for purifying hydroxymethylfurfural using non-functional polymeric resins - Disclosed are methods of at least partially purifying HMF from an aqueous mixture containing reactants and products of HMF synthesis from fructose that relies on use of non-functional polymeric resins. A first type of non-functional polymeric resin preferentially adsorbs HMF relative to fructose and is used to remove a majority of fructose from the reaction mixture. HMF is desorbed from the first non-functional polymeric resin with an organic solvent such as acetone. A second type of non-functional polymeric resin preferential adsorbs furfural from an aqueous reaction mixture allowing HMF to pass through. In one embodiment, these non-functional polymeric resins may be used alone in combination with each other to obtain HMF of high purity. In other embodiments, one or more of the foregoing non-functional polymeric resin resins is used in combination with cation exchange chromatography to still further purify the HMF. | 2009-01-15 |
20090018353 | METHOD FOR PREPARATION OF AMORPHOUS, ANHYDROUS CRYSTALLINE OR HYDRATED CRYSTALLINE DOCETAXEL - This invention is directed to a method for the preparation of docetaxel having an amorphous, anhydrous crystalline, or hydrated crystalline structure. In accordance with the invention, highly pure amorphous, anhydrous crystalline, or hydrated crystalline docetaxel can be produced with a high yield by using a solvent precipitation method, colloid formation method, etc. | 2009-01-15 |
20090018354 | PREPARATION OF ALPHA-HYDROXY AND ALPHA-AMINO KETONES - A process for the preparation of an 1,1-disubstituted oxirane is disclosed, wherein an organic sulphide is reacted in a polar solvent with an educt containing a leaving group attached to a primary or secondary carbon atom, and/or the sulfonium salt formed in this way is reacted with a ketone in presence of a base and a polar solvent. Oxiranes of the type obtained may be further converted into the corresponding α-hydroxyketone or α-aminoketone, either in one step by subjecting to aerobic oxidation in the presence of a transition metal catalyst, or in two steps by hydrolyzation in the presence of an aqueous acid to the corresponding dialcohol and subsequent selective oxidation. Further described are some novel epoxide intermediates. The α-hydroxyketones and α-aminoketones thus obtainable are useful inter alga as photoinitiators. | 2009-01-15 |
20090018355 | Process for Crystallizing an Epoxy Compound - A process for crystallizing an epoxy compound, which comprises the steps of: | 2009-01-15 |
20090018356 | Crystalline polymorph of exemestane - New crystalline polymorph of exemestane characterized by a powder X-ray diffraction pattern having peaks at 10.7±0.1, 15.9±0.1, and 18.1±0.1 2-theta degree. | 2009-01-15 |
20090018357 | Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use - The present invention discloses boronic acids and esters of phospholipid ether analogs and methods for their synthesis and use. The boronic acids and esters of phospholipid ether analogs described herein can be used in treating cancer and in particular can be used in conjunction with radiation therapy, such as external beam radiation therapy and neutron capture therapy to specifically target and kill cancer cells. | 2009-01-15 |
20090018358 | Polyglycerol fatty acid ester and composition containing same - A polyglycerol fatty acid ester formed by esterifying a polyglycerol and a fatty acid, wherein the polyglycerol has a hydroxyl value of 1200 or less and primary hydroxyl groups in an amount of 50% or more of the total hydroxyl groups, and an emulsified or solubilized composition, foodstuff, and cosmetics, each containing the polyglycerol fatty acid ester. | 2009-01-15 |
20090018359 | SYNTHETIC PETROLEUM SULFONATE - A synthetic petroleum sulfonate prepared by a process comprising (a) reacting at least one aromatic compound with a mixture of olefins selected from olefins having from about 8 to about 100 carbon atoms, in the presence of an acidic ionic liquid catalyst, wherein the resulting product comprises at least about 50 weight percent of a 1,2,4 tri-substituted aromatic compound or a 1,2,3 tri-substituted aromatic compound or mixtures thereof; (b) reacting the product of (a) with sulfur trioxide, which has been diluted with air; and (c) neutralizing the product of (b) with an alkali or alkaline earth metal hydroxide. | 2009-01-15 |
20090018360 | PROCESS FOR PREPARATION OF ALKYL AND ALCOXYALKYL-ALPHA-CYANOACRYLATES BY DEPOLYMERISATION OF POLY(ALKYL-ALPHA CYANOACRYLATES) OR POLY(ALCOXYALKYL-ALPHA-CYANOACRYLATES) AND ITS USAGE AS TECHNICAL AND/OR MEDICAL ADHESIVE - This invention is related to the preparation of alkyl or alkoxyalkyl-α-cyanoacrylates in monomeric form by depolymerisation of the corresponding poly(alkyl-α-cyanoacrylates) or poly(alkoxyalkyl-α-cyanoacrylates) (PCA). The PCA's are obtained preferably by base-catalyzed condensation of a cyanoacetate with formaldehyde (or a polymer of the latter). According to the invention, the poly(alkyl-α-cyanoacrylate) or poly(alkoxyalkyl-α-cyanoacrylate), the condensation product, is mixed with a depolymerisation system comprising phosphorus pentoxide P | 2009-01-15 |
20090018361 | PROCESS OF PRODUCING HIGH PURITY TEREPHTHALIC ACID - A problem of the invention is to provide a process of producing high purity terephthalic acid by selectively recovering p-toluic acid in wastewater which has hitherto been discarded and using it as a raw material of terephthalic acid. | 2009-01-15 |
20090018362 | ACRYLIC ACID PREPARATION METHOD - The invention relates to a method for preparing acrylic acid from propylene, comprising the oxidation of propylene to acrolein and a second step comprising the oxidation of acrolein to acrylic acid, including a glycerol dehydration step preformed in the presence of a gas containing propylene and, more specifically, in the presence of the reaction gas originating from the propylene to acrolein oxidation step. The inventive method enables the use, in part, of renewable raw material, while increasing acrylic acid production. | 2009-01-15 |
20090018363 | PROCESS FOR PRODUCING NITROISOUREA DERIVATIVES - Disclosed is an improved process for producing nitroisourea derivatives which is necessary for producing nitroguanidine derivatives having an insecticidal activity. Specifically disclosed is a process for producing nitroisourea derivatives represented by the following general formula (3), which is characterized in that nitroisourea derivatives represented by the following general formula (1) and amines represented by the following general formula (2) or a salt thereof are reacted in the presence of a catalytic amount of a hydrogen carbonate, | 2009-01-15 |
20090018364 | METHOD FOR NITRATING ISOUREA - An object of the present invention is to industrially advantageously produce N-nitroisoureas or a salt thereof which is useful as a synthetic intermediate for pharmaceuticals and pesticides. The present invention relates to a process for producing a compound represented by the formula (2): | 2009-01-15 |
20090018365 | Methods for Preparing O-Desmethylvenlafaxine - The present invention provides an efficient method of making O-desmethyl-venlafaxine. | 2009-01-15 |
20090018366 | PRODUCTION AND USE OF SUPPORTED ACTIVATED BASE METAL CATALYSTS FOR ORGANIC TRANSFORMATION - Method for the production of supported activated metal catalysts, whereby an alloy, a metal powder, a pore builder is dispersed in a water, the dispersion is sprayed on a support which is the dried, calcined and activated. The catalysts can be used for organic transformations, i.e. for hydrogenation reactions. | 2009-01-15 |
20090018367 | Process for Preparing Cyclohexanone and Cyclohexanol - The present invention relates to a process for preparing cyclohexanone and cyclohexanol, said process comprising (a) neutralising acids and/or carbon dioxide present in an organic solution further comprising cyclohexylhydroperoxide by mixing the organic solution with a first aqueous base solution at a temperature of from 50 to 80° C. to form a first mixture comprising a first aqueous phase with a pH of from 8.5 to 13 and a first organic phase, (b) separating first aqueous phase from the first mixture resulting in a remaining mixture comprising first organic phase, (c) decomposing cyclohexylhydroperoxide present in said remaining mixture by mixing said remaining mixture with a second aqueous base solution at a temperature of from 60 to 110° C. to form a second mixture comprising a second aqueous phase and a second organic phase comprising cyclohexanone and cyclohexanol, (d) separating the second aqueous phase from the second organic phase at a temperature higher than 80° C. | 2009-01-15 |
20090018368 | EXPEDITIOUS SYNTHESIS OF DPD - This invention provides a practical synthesis route for 4,5-dihydroxypentane-2,3-dione (DPD), an unstable small molecule which is proposed to be the source of universal signaling agents for quorum sensing in bacteria. The synthesis route includes new intermediates and allows preparation of isotopically-labeled DPD and ent-DPD. The method provides sufficient quantities of DPD for study of spontaneous binding of borate to DPD, the signal for the marine bacteria | 2009-01-15 |
20090018369 | PROCESS FOR PREPARING ERIANIN - A process for preparing Erianin (Dihydro Combretastation A-4), wherein 3,4,5-trimethoxy benzaldehyde is converted to phosphonium salt or phosphonate ester or the likes thereof, then reacted with isovanillin (3-hydroxyl-4-methoxyl benzaldehyde) including a protected hydroxyl in the 3-position, followed by hydrogenation and deprotection. | 2009-01-15 |
20090018370 | Industrial process for production of diol - It is an object of the present invention to provide a specific apparatus and process for producing a diol by taking a cyclic carbonate and an aliphatic monohydric alcohol as starting materials, continuously feeding the starting materials into a continuous multi-stage distillation column A in which a catalyst is present, carrying out reactive distillation in the column A, continuously withdrawing a low boiling point reaction mixture A | 2009-01-15 |
20090018371 | METHODS AND APPARATUS FOR PRODUCING ALCOHOLS FROM SYNGAS - Methods and apparatus for producing alcohols from syngas are disclosed herein. In some variations, syngas is catalytically converted to methanol in a first reaction zone, and residual syngas from the first reaction zone is then catalytically converted to ethanol in a second reaction zone. Also, in some variations, syngas is catalytically converted to methanol in high yield in a first reaction zone, and the methanol is then converted (optionally, with additional syngas) to ethanol in a second reaction zone. | 2009-01-15 |
20090018372 | METHODS AND APPARATUS FOR PRODUCING ALCOHOLS FROM SYNGAS - Methods and apparatus for producing alcohols from syngas are disclosed herein. In some variations, syngas is catalytically converted to alcohols. The alcohols can be subjected to drying to produce an intermediate alcohol product, followed by distilling the intermediate product to produce a purified ethanol product for use in liquid fuels. | 2009-01-15 |
20090018373 | OXIDATION REACTOR AND OXIDATION PROCESS - The invention relates to an oxidation reactor and process suited to operate the said reactor which houses a multitude of gas-tight and oxygen conductive membrane elements the external surfaces of which are arranged on the side of a reaction chamber to be filled with catalyst and which constitute, in conjunction with the membrane elements penetrable by oxygenous gas, a connection between the distribution chamber and a collection chamber and/or discharge section of the reactor. The reactor is characterised in that one or several spacer pieces establish a defined minimum distance between the external surface of a membrane element and the catalyst in the reaction chamber. | 2009-01-15 |
20090018374 | HYDROGENATION CATALYST AND USE THEREOF FOR HYDROGENATING FISCHER-TROPSCH ENDPRODUCTS - A hydrogenation catalyst particularly suitable for hydrogenating oxygenates in a hydrogenation unit of a Fischer-Tropsch plant is disclosed. A preferred embodiment comprises more than 5% and less than 20% nickel based on a wide pore alumina support. The catalyst successfully hydrogenates oxygenates which otherwise tend to poison a catalyst in a hydroconversion unit downstream. Moreover, the temperature at which the unwanted hydrogenolysis of long chain paraffins to methane occurs is higher for one catalyst disclosed herein than a comparable known catalyst. This allows the hydrogenation plant to operate at a higher temperature. | 2009-01-15 |
20090018375 | COPRODUCTION OF HYDROFLUOROOLEFINS - Disclosed is a process for the co-manufacture of the hydrofluoroolefins HFC-1225ye and HFC-1234yf. The process comprises contacting a blend of 1,1,1,2,3,3-hexafluoropropane and 1,1,1,2,3-pentafluoropropane at a temperature of from about 200° C. to about 500° C. with a catalyst, optionally in the presence of an inert gas. The catalyst includes, but is not limited to, aluminum fluoride; fluorided alumina; metals on aluminum fluoride; metals on fluorided alumina; oxides, fluorides, and oxyfluorides of magnesium, zinc and mixtures of magnesium and zinc and/or aluminum; lanthanum oxide and fluorided lanthanum oxide; chromium oxides, fluorided chromium oxides, and cubic chromium trifluoride; carbon, acid-washed carbon, activated carbon, three dimensional matrix carbonaceous materials; and metal compounds supported on carbon. The metal compounds are oxides, fluorides, and oxyfluorides of at least one metal selected from the group consisting of sodium, potassium, rubidium, cesium, yttrium, lanthanum, cerium, praseodymium, neodymium, samarium, chromium, iron, cobalt, rhodium, nickel, copper, zinc, and mixtures thereof. The product hydrofluoroolefins are separated from unreacted hydrofluorocarbons and hydrogen fluoride. In another embodiment, the unreacted hydrofluorocarbons optionally may be recirculated back through the process. | 2009-01-15 |
20090018376 | Catalytic process for the preparation of fluorinated halocarbons - A process is described for the preparation of 2-chloro-1,1,1-difluoroethane by the reaction of 1,2-dichloro-1,1-difluoroethane with hydrogen fluoride. in the presence of a fluorination catalyst. The process utilizes a rate enhancing reagent that is trichloroethylene, is 1-fluoro-1,2,3-trichloroethane or an aromatic rate enhancing reagent having the formula | 2009-01-15 |
20090018377 | Catalytic process for the preparation of fluorinated halocarbons - A process is described for the preparation of a reaction stream comprising 2-chloro-1,1,1-difluoroethane substantially free of oligomeric tars. The process proceeds in a first step by reacting trichloroethylene with hydrogen fluoride in the presence of a hydrofluorination catalyst at a temperature from about −5° to about 30° C. for a time sufficient to form a reaction mixture comprising 1,1,2-trichloro-1-fluoroethane substantially free of trichloroethylene. In the second step of the process, the reaction mixture is then reacted with hydrogen fluoride in the presence of a hydrofluorination catalyst at a temperature of from about 100° to about 175° C. for a time sufficient to form a reaction stream of 2-chloro-1,1,1-difluoroethane substantially free of oligomeric tars. | 2009-01-15 |
20090018378 | Oxygenate To Olefins Process Involving Supercritcal Conditions - This invention, in one embodiment, is drawn to a process for forming olefin product by contacting an oxygenate with an olefin-forming catalyst under supercritical conditions to form an olefin product. This invention also relates to methods for activating molecular sieve catalyst, regenerating molecular sieve catalyst, and forming and/or disposing a co-catalyst within a molecular sieve catalyst, each under supercritical conditions. | 2009-01-15 |
20090018379 | Synthesis Of Chabazite Structure-Containing Molecular Sieves And Their Use In The Conversion Of Oxygenates To Olefins - In a method of synthesizing a silicoaluminophosphate or aluminophosphate molecular sieve comprising a CHA framework-type material, a synthesis mixture is provided comprising a source of aluminum, a source of phosphorus, optionally a source of silicon and at least one organic template of formula (I): | 2009-01-15 |
20090018380 | PROCESS AND DEVICE FOR IMPROVED SEPARATION OF PARAXYLENE IN A SIMULATED MOVING BED - Process for separating paraxylene with a purity that is at least equal to 99.5% by weight from an aromatic feedstock F in a single adsorption stage in a simulated moving bed (SMB), comprising different numbers of beds, allocated to a zone 1 between the supply of the desorbent D and the draw-off of the extract E; a zone 2 between the draw-off of the extract E and the supply of the feedstock F; a zone 3 between the supply of the feedstock and the draw-off of the raffinate R; a zone 4 between the draw-off of the raffinate R and the supply of the desorbent D, wherein an SMB of 12 adsorbent beds has bed configuration (2, 5, 3, 2), an SMB of 15 adsorbent beds has bed configuration (3, 6, 4, 2), or an SMB of 19 adsorbent beds has bed configuration (4, 7, 6, 2), wherein the desorbent in this latter case is paradiethylbenzene. | 2009-01-15 |
20090018381 | CONTAINER FOR ACCOMADATING MEDIA, AND METHOD FOR THE PRODUCTION AND VERIFICATION OF THE LEAKPROOFNESS OF SAID CONTAINER - The invention relates to a method for verifying the leakproofness of a container used for accommodating preferably liquid media as well as a plastic container that is composed of several segments ( | 2009-01-15 |
20090018382 | METHODS AND APPARATUS FOR CONTAINING HAZARDOUS MATERIAL - Methods and apparatus for containing a hazardous material according to various aspects of the present invention operate in conjunction with a container having two compartments. The first compartment is configured to contain the hazardous material, and the second compartment contains a hazard control material. The container may further comprise a wall separating the first compartment from the second compartment. The wall is configured to open upon occurrence of a trigger event. | 2009-01-15 |
20090018383 | EXPANDABLE BRACHYTHERAPY DEVICE WITH EXPANDABLE CAGE HAVING A CONTROLLED DIAMETER - A brachytherapy device may include an expandable outer cage an expandable inner cage positioned within the outer cage and configured to receive radioactive material at its perimeter. The expandable inner cage may be configured to expand, and the outer cage may be configured to expand to a variable diameter greater than the inner cage diameter so as to fill resected cavities of various diameters. | 2009-01-15 |
20090018384 | Portable, Modular Transcranial Magnetic Stimulation Device - A portable, modular transcranial magnetic stimulation device comprises a power supply unit, an energy storage unit, a charge recovery unit, a control unit, and at least one stimulation coil unit. The power supply unit generates specified voltages from a low voltage supply. The energy storage unit stores voltage received from the power supply unit until it is needed to generate a stimulation pulse and preferably includes discharge circuitry for discharging the stored voltage. The stimulation coil unit stores energy received from the energy storage unit as a strong current for application of magnetic stimulation to a patient. The charge recovery unit converts energy stored as current in the stimulation coil unit back to energy stored as voltage in the energy storage unit. The control unit controls the operation of the power supply unit, the energy storage unit, and the charge recovery unit. Biphasic, multiphasic, and monophasic stimulators may be implemented. | 2009-01-15 |
20090018385 | URETHRA PRESSURE CONTROL VALVE TO CONTROL INCONTINENCE - A surgically implantable urethra pressure control adjustable valve for male and female patients is described. The valve comprises a clamp positionable about a urethra in a patient's body. The clamp has a circumferential wall having a first and a second opening. The openings are oppositely spaced apart at predetermined locations to provide for the passage of the urethra through the circumferential wall. A pressure abutment element is provided inside the circumferential wall and disposed between an inner wall surface of the circumferential wall and the urethra and actuable to apply a contained control pressure against the urethra to close the urethra by pinching same against a diametrically opposed immovable abutment element formed in the circumferential wall and projecting inwardly therein. The contained controlled pressure is adjustable and selected so that liquid pressure from a bladder associated with the urethra and under the influence of muscle control will cause the urethra to open against the contained controlled pressure to discharge liquid from the bladder and to automatically close once the pressure from the bladder is discontinued by muscle control. | 2009-01-15 |
20090018386 | Seeding Implantable Medical Devices with Cells - The invention is directed to apparatus and methods for seeding an implantable medical device, such as a vascular prosthesis, with cells, such as endothelial cells. The invention supports techniques for seeding a luminal surface of the device with axial centrifugation. Cells are introduced in suspension into the lumen of the device, and the device is subjected to centrifugation around a longitudinal axis defined by the lumen. Axial centrifugation causes the cells to concentrate toward the luminal surface. Shortly after axial centrifugation, the seeded device can be presented for implantation in a patient. | 2009-01-15 |
20090018387 | Repair of Vaginal Prolapse - Described are methods and devices useful for treating pelvic prolapse, such as vaginal prolapse, the methods involving a tissue path that extends through pelvic floor (muscle) tissue. | 2009-01-15 |
20090018389 | METHODS AND SYSTEMS FOR TISSUE MANIPULATION - An endoluminal treatment device and method includes introducing an endoluminal device into a lumen of a patient and engaging a wall of the lumen with an implant device. The implant device can be a drug delivery device or medical device. | 2009-01-15 |
20090018390 | Medical system - A medical system according to the present invention includes: a medical instrument provided with a treatment portion for performing treatment operations on living body tissue; a treatment portion displacement mechanism for displacing the position of the treatment portion of the medical instrument; a treatment detection portion that detects whether the treatment portion is in a treatment state or a non-treatment state; and a control portion that controls displacement of the treatment portion by controlling the treatment portion displacement mechanism according to detection results from the treatment detection portion. | 2009-01-15 |
20090018391 | METHODS AND DEVICES FOR PLACEMENT OF AN INTRA-ABDOMINAL OR INTRA-THORACIC APPLIANCE THROUGH A NATURAL BODY ORIFICE - Natural orifice transenteric surgical methods and devices for placing a semi-circumferential appliance around a hollow bodily organ such as the stomach. In one alternative embodiment, such an appliance is placed in order to reduce the inner volume of the stomach. | 2009-01-15 |
20090018392 | ENDOSCOPE - An endoscope ( | 2009-01-15 |
20090018393 | CATHETER FOR IN VIVO IMAGING - A catheter for in vivo imaging comprising a monolithic outer sheath terminating in a monolithic atraumatic tip having a guidewire lumen. The catheter for in vivo imaging comprising a rotary drive shaft that passes through a central lumen of the monolithic outer sheath to impart rotary motion. | 2009-01-15 |
20090018394 | Surgical Instrument System - The invention relates to a surgical instrument system, which comprises a hollow shaft as well as a shaft-type instrument that can be inserted into the hollow shaft. To create a surgical instrument system that consists of a hollow shaft and of a medical instrument that can be inserted into the hollow shaft and that is both simple in construction and capable of a range of uses, it is proposed according to the invention that at least one cam that reduces the inside diameter of the hollow shaft should be positioned on the interior of the hollow shaft. | 2009-01-15 |
20090018395 | WIRELESS IN-VIVO INFORMATION ACQUIRING APPARATUS AND WIRELESS IN-VIVO INFORMATION ACQUIRING SYSTEM - A system control circuit | 2009-01-15 |
20090018396 | Indwelling device for encapsulated medical device, in-vivo indwelling device for capsule endoscope, and capsule-indwelling medical device - An already-existing and general-purpose capsule endoscope for alimentary canal is enabled to be used to monitor a body cavity by directly diverting the already-existing and general-purpose capsule endoscope to a body-cavity-indwelling capsule endoscope in a simple and secure manner. An indwelling device for an encapsulated medical device of the invention includes a latching portion | 2009-01-15 |
20090018397 | ENDOSCOPE - An endoscope ( | 2009-01-15 |
20090018398 | CAPSULE ENDOSCOPE - A capsule endoscope has a solid image sensor introduced into a subject for picking up an image in the subject. The capsule endoscope includes a light-emitting unit for emitting illumination light for illuminating a view field of the solid image sensor; a lens frame for holding a lens to focus an image in the subject on a light-receiving surface of the solid image sensor, the lens frame having an upper end portion located at a position lower than an upper surface of the light-emitting unit; and a shield unit for shielding, from the illumination light, at least a partial area of the upper end portion of the lens frame which receives the illumination light. | 2009-01-15 |
20090018399 | Surgical access system and related methods - A surgical access system including a tissue distraction assembly | 2009-01-15 |
20090018400 | SURGICAL RETRACTOR SYSTEMS AND ILLUMINATED CANNULAE - This invention includes surgical retractors that comprise an expandable frame that includes at least two base components, a connector, and at least two retractor blades attached to the expandable frame. Also included are surgical retractors that comprise a housing component that includes a cylindrical portion and a contiguous blade portion, assemblies comprising a surgical retractor assembled to at least one obtruator, illuminated surgical cannulas, and methods of using the same during a surgical procedure. | 2009-01-15 |
20090018401 | SURGICAL RETRACTOR POSITIONING DEVICE - A surgical retractor positioning device is provided to create a surgical working field in a minimally invasive and flexible manner. In one embodiment, the device can include a frame and an arm connected to the frame. The arm can include a proximal end, a distal end having a distal end axis, and a major axis, wherein the distal end axis is movable relative to the proximal end, whereby the distal end axis can intersect the major axis at an angle. The device can include at least one blade connected to the distal end of the arm, wherein the blade is fixably rotatable about the major axis. The device can include at least two arms. | 2009-01-15 |
20090018402 | Electronic device for health index measurement and control method of the same - The present invention allows easily performing various types of controls and improving productivity without adding a special communication section. The present invention includes a power receiving section | 2009-01-15 |
20090018403 | TRACKABLE IMPLANTABLE SENSOR DEVICES, SYSTEMS, AND RELATED METHODS OF OPERATION - An implantable biocompatible sensor unit includes a sensor body of a biocompatible material configured for in vivo placement proximate a tumor treatment site. The sensor body includes at least one sensor element are configured to provide data corresponding to treatment of the tumor treatment site. The sensor body further includes a transmitter coil and associated electronic components configured for wireless transmittal of the data to a spatially remote receiver. In addition, the sensor body includes a high-atomic weight member that is configured to be detectable by an imaging modality. The sensor unit is configured to be inductively powered to wirelessly transmit the data to the remote receiver while remaining implanted proximate the tumor treatment site. Related medical systems and methods of operation are also discussed. | 2009-01-15 |
20090018404 | Cardiovascular Autonomic Neuropathy Testing Utilizing an Implantable Medical Device - A test system and method for cardiovascular autonomic neuropathy that incorporates an implanted medical device. One aspect of the invention relates to a system for performing cardiovascular autonomic neuropathy (CAN) testing in a diabetic patient having an implantable medical device (IMD) that includes a plurality of implantable physiological sensors and that is configured to transmit a wireless signal corresponding to a sensed physiological activity and to receive wireless signals. The system further includes one or more non-implantable physiological sensors, where the non-implantable physiological sensors are each configured to transmit a signal corresponding to a sensed physiological parameter, and a monitor device having a patient interface. The monitor device is configured to interface with a patient, including directing the patient to answer health related questions and use one or more of the non-implantable physiological sensors. The monitor device is also configured to receive signals, including signals from the IMD and the non-implantable physiological sensors. The system is configured to provide an indication of the presence or progression of CAN. | 2009-01-15 |
20090018405 | Exercise load measuring device - There is provided an exercise load measuring device that can measure states of metabolism during exercise. The exercise load measuring device includes: a hemoglobin detecting portion | 2009-01-15 |
20090018406 | Method and Device for Assessing Carbohydrate-to-Insulin Ratio - A system and a method for determining an assessed carbohydrate to insulin ratio of a patient is described. The system and the method can comprise a memory component adapted for storing an initial set of values comprising at least one of a blood glucose level, a target blood glucose level, an insulin sensitivity, and, an estimated carbohydrate to insulin ratio. The system and the method can also comprise a bolus selection component adapted for selecting a test bolus corresponding to the determined initial set of values and a planned meal. In one implementation, the bolus selection component can receive bolus dose input from a user. In another implementation, the bolus selection component can estimate the bolus dose using a set of available inputs (e.g. the amount of carbohydrates in the planned meal). The system and the method can further comprise a user interface component adapted for receiving a confirmation that the test bolus has been administered to the patient. In some implementations, the user interface component can be adapted for selecting a meal of a known content. | 2009-01-15 |
20090018407 | Computational user-health testing - Methods, apparatuses, computer program products, devices and systems are described that carry out accepting user data from an interaction between a user and at least one device-implemented application unrelated to user-health testing; mapping the user data from the interaction between the user and the at least one device-implemented application unrelated to user-health testing to at least one user-health test function set; accepting brain activity measurement data proximate to the interaction between the user and the at least one device-implemented application unrelated to user-health testing; and selecting at least one user-health test function at least partly based on the at least one user-health test function set and the brain activity measurement data. | 2009-01-15 |
20090018408 | APPARATUS AND METHOD FOR PROCESSING PULSE WAVES - Pulse wave signal data expressing the pulse wave of a subject and body movement signal data expressing body movements of the subject are obtained so that a correlation coefficient expressing the degree of correlation between the pulse wave signal data and the body movement signal data is calculated. One or more pieces of the pulse wave signal data in which the correlation coefficient is equal to or larger than a predetermined threshold value are eliminated. | 2009-01-15 |
20090018409 | DEVICE FOR DETERMINING RESPIRATORY RATE AND OTHER VITAL SIGNS - A body-worn sensor that measures respiratory rate and other vital signs using an acoustic sensor (e.g., a small-scale sensor). The body-worn sensor features a chest-worn patch sensor that combines both the acoustic sensor and an ECG electrode into a single adhesive patch. To measure blood pressure, the device additionally performs a ‘composite’ PTT-based measurement that features both pressure-dependent and pressure-free measurements. The acoustic sensor measures respiration rate by recording sounds related to the patient's inspiration and expiration. The acoustic sensor is typically placed near the patient's trachea, but can also be placed on the middle right and left side of the chest, and the middle right and left side of the back. | 2009-01-15 |
20090018410 | BODY PARAMETER SENSING - A body parameter sensing arrangement comprising clothing ( | 2009-01-15 |
20090018411 | Analyte Test Device - An analyte test device is constructed as an integrated, single-use, disposable cartridge which can be releasably installed into a compatible analyte test monitor. In use, the device can be used in conjunction with the monitor to lance the skin of a patient to create a blood sample and, in turn, calculate the concentration of a particular analyte in the expressed blood sample. In one embodiment, the device includes a base and a cover which are affixed together to create a test cartridge which has a substantially flat and low profile design. A lancet carrier is disposed between the base and the cover and includes a anchor fixedly mounted on the base and a lancet support member which is slidably mounted on the base, the anchor and the lancet support member being connected by a spring. A lancet is removably mounted on the lancet support member is disposed directly beneath an analyte test strip which secured to the underside of the cover. In another embodiment, the device includes a cylindrical housing with an open top end and an open bottom end. A spring biased lancet is slidably mounted within the cylindrical housing. An analyte test strip is fixedly mounted within the cylindrical housing and is disposed at an acute angle relative to the lancet. | 2009-01-15 |
20090018412 | Medical unit with an apparatus for an examination of a patient and an associated method - The invention relates to a medical unit with an apparatus designed for the examination or treatment of a patient. The medical unit comprises at least one means designed for the collection or analysis of at least one substance exuded from the body of the patient during the course of a bodily process concomitantly to the examination or treatment of the patient with the apparatus. | 2009-01-15 |
20090018413 | IMPLANTABLE MEDICAL DEVICE FOR DIAGNOSTIC SENSING - An implantable medical device is provided for use with an external detector to detect an analyte in vivo. In one embodiment, the device consisting essentially of a substrate; a plurality of discrete reservoirs located in the substrate, each reservoir having at least one opening; a reacting component contained in each reservoir; and at least one non-degradable barrier layer covering each reservoir opening, the barrier layer being permeable to an analyte to be detected, wherein the reacting component remains inside the reservoirs and can react with the analyte to be detected, and wherein the device is adapted for implantation into the body of a patient. | 2009-01-15 |
20090018414 | Subcutanous Blood Vessels Imaging System - A real time imaging system is described which displays subcutaneous veins whereby facilitating diagnosis, inspection and easy intravenous access for administration of drugs. The imaging system comprises an infrared source ( | 2009-01-15 |
20090018415 | Methods and Apparatuses for Noninvasive Determinations of Analytes using Parallel Optical Paths - The present invention provides methods and apparatuses for accurate noninvasive determination of tissue properties. Some embodiments of the present invention comprise an optical sampler having an illumination subsystem, adapted to communicate light having a first polarization along a first path to a tissue surface; a collection subsystem, adapted to collect light having a second polarization communicated from the tissue along a second path after interaction with the tissue; wherein the first polarization is different from the second polarization; and wherein the first path and the second path are substantially parallel for at least of portion of each path. | 2009-01-15 |
20090018416 | Analyte Concentration Measurement Device - A method for measuring concentration of an analyte in body fluid comprises acquiring a body fluid sample, emitting light into the body fluid sample, and detecting emitted light intensity on a plurality of optical paths through the body fluid sample. A plurality of optical filters are arranged in respective optical paths of the optical path plurality comprising at least a first optical filter with light absorption by an analyte and water and a second optical filter with light absorption to water alone. Light intensity passed through the first optical filter and passed through the second optical filter is measured and analyte concentration is determined based on a ratio of intensities detected at a detector in an optical path intersected by the first optical filter and detected at a detector in an optical path intersected by the second optical filter. | 2009-01-15 |
20090018417 | APPARATUS MONITORING SIGNAL IN SITU - For repeatedly measuring signals from a fixed position of a tissue to monitor the blood composition, we use one or more elastic membranes at upper and lower parts of the extruded tissue together with a cone-shaped guide. This will constrain the tissue in the fixed position when a signal guide is used for measuring signals from the fixed position of the tissue repeatedly. The signals can be from an aggregate of the designated composition with the other ingredients of the blood. | 2009-01-15 |
20090018418 | EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT - Embodiments of the present invention relates to analyte sensors. In particular, the preferred embodiments of the present invention relate to non-consuming intravascular glucose sensors based on fluorescence chemistry. | 2009-01-15 |
20090018419 | BIOSENSORS, COMMUNICATORS, AND CONTROLLERS MONITORING EYE MOVEMENT AND METHODS FOR USING THEM - Biosensor, communicator, and/or controller apparatus, systems, and methods are provided for monitoring movement of a person's eye. The apparatus includes a device configured to be worn on a user's head, a light source for directing light towards one or both eyes of the user, one or more image guides on the device for viewing one or both eyes of the user, and one or more cameras carried on the device and coupled to the image guides for acquiring images of the eyes and/or the user's surroundings. The apparatus may include a cable and/or a transmitter for transmitting image data from the camera to a remote location, e.g., to processor and/or display for analyzing and/or displaying the image data. A system including the apparatus may be used to monitor one or more oculometric parameters, e.g., pupillary response, and/or to control a computer using the user's eyes instead of a mouse. | 2009-01-15 |
20090018420 | Apparatus for Non-Invasive Spectroscopic Measurement of Analytes, and Method of Using the Same - An apparatus for spectroscopic evaluation of a subject's body fluids may be used at the interstitial region adjacent to or in between a subject's extremities using a spectroscopic probe. The spectroscopic probe may possess one or more of the movements such as rotational, translational, and/or vertical freedom necessary for the probe to contact the subject's tissue at a consistent angle and pressure while accommodating the different size of the subject's extremities, and may be housed in a device optimized for attaining reproducible blood flow to the region of the subject that is measured, and for minimizing the effects of the housing pulling, stretching, pressing, compressing the subject's skin. A pressure sensor may be used to ensure that measurements are taken at an optimal pressure. A touch sensor may be used to activate a system and/or to ensure flushness. In addition, the spectroscopic measurement may be coupled with a temperature measurement means that detects the subject's local body temperature in or near the region being measured, or the subject's core or mean body temperature, or the ambient temperature proximate to the probe, or any combination of those measurements. The system may also include one or more indicators to communicate information to a test subject. | 2009-01-15 |
20090018421 | PHYSIOLOGICAL STRESS DETECTOR DEVICE AND SYSTEM - A non-invasive device and a system for monitoring and measuring blood saturation and heart pulse rate of a baby or infant is provided. The device includes a housing unit configured to be integrated within apparatus, which is attachable proximate to a limb being measured. The housing unit includes at least one light source, providing light directed toward the surface of the limb, a light detector spaced apart from the light source and sensitive to intensity levels of the light reflected from the limb and a processing unit for processing the intensity signals received from the light detector for producing output signals. The device may determine the level of the blood constituent and may also use this level for monitoring and/or to activate an alarm when the level falls outside a predetermined range. | 2009-01-15 |
20090018422 | VITAL SIGN MONITOR FOR CUFFLESSLY MEASURING BLOOD PRESSURE USING A PULSE TRANSIT TIME CORRECTED FOR VASCULAR INDEX - A method and apparatus for measuring a patient's blood pressure featuring the following steps: 1) measuring a time-dependent optical waveform with an optical sensor; 2) measuring a time-dependent electrical signal with an electrical sensor; 3) estimating the patient's arterial properties using the optical waveform; 4) determining a pulse transit time (PTT) from the time-dependent electrical signal and the time-dependent optical waveform; and 5) calculating a blood pressure value using a mathematical model that includes the PTT and the patient's arterial properties. | 2009-01-15 |
20090018423 | PATCH FOR EXTRACTING GLUCOSE - Disclosed herein is a patch for extracting glucose. The patch of the present invention includes a frame ( | 2009-01-15 |
20090018424 | ANALYTE SENSOR - Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system. | 2009-01-15 |
20090018425 | ANALYTE MONITORING: STABILIZER FOR SUBCUTANEOUS GLUCOSE SENSOR WITH INCORPORATED ANTIGLYCOLYTIC AGENT - An analyte sensor including an antiglycolytic agent or a precursor thereof and a chelating agent that stabilizes the antiglycolytic agent positioned proximate to the working electrode of the sensor. Also provided are systems and methods of using the electrochemical analyte sensors in analyte monitoring. | 2009-01-15 |
20090018426 | DEVICE AND METHODS FOR CALIBRATING ANALYTE SENSORS - The present invention relates to methods and systems for multipoint calibration of an analyte sensor. More specifically, the methods can be used to calibrate glucose sensors. | 2009-01-15 |
20090018427 | ELECTRODE ARRAY - A disposable electrode array | 2009-01-15 |
20090018428 | Knitted transducer devices - There is disclosed a knitted transducer device comprising a knitted structure having at least one transduction zone, in which the transduction zone is knitted with electrically conductive fibres so that deformation of the knitted structure results in a variation of an electrical property of the transduction zone. | 2009-01-15 |
20090018429 | Method and system for acquiring biosignals in the presence of HF interference - The present invention, herein is a method and apparatus that significantly limits the effect of high frequency (“HF”) interferences on acquired electro-physiological signals, such as the EEG and EMG. Preferably, this method comprises of two separate electronic circuitries and steps or electronics for processing the signals. One circuit is used to block the transmission of HF interferences to the instrumentation amplifiers. It is comprised of a front-end active filter, a low frequency electromagnetic interference (“EMI”) shield, and an isolation barrier interface which isolates the patient from earth ground. The second circuit is used to measure the difference in potential between the two isolated sides of the isolation barrier. This so-called “cross-barrier” voltage is directly representative of the interference level that the instrumentation amplifier is subjected to. This circuit is used to confirm that the acquired signals are not corrupted by the interference. | 2009-01-15 |
20090018430 | METHOD FOR PRODUCING A MEDICAL IMAGE AND AN IMAGING DEVICE - A method for examining a patient in a medical imaging device is provided. The method includes measuring a pressure inside the body of the patient over a period of time during the examination, recording measurement data originating in the patient while the examination is in progress, reconstructing the medical image from the recorded measurement data, wherein the recording of the measurement data is controlled by the measured pressure and/or wherein the measured pressure is taken into account while the medical image is being reconstructed from the recorded measurement data. | 2009-01-15 |
20090018431 | Method and apparatus for imaging functional processes in the brain - A method and an apparatus are disclosed for imaging functional processes in the brain. In order to be able to correlate the results of MEG examinations with anatomical information and metabolic data, a positron emission tomography measurement is recorded in at least one embodiment by at least one radiation detector, a magnetic resonance imaging measurement is recorded by a coil and a radio-frequency antenna device and a magnetoencephalography measurement is recorded by a plurality of magnetic field sensors, the positron emission tomography measurement and the magnetic resonance imaging measurement being substantially undertaken at the same time, so that the records of the positron emission tomography measurement and the magnetic resonance tomography measurement are isocentric. In at least one embodiment, an evaluation apparatus is provided for carrying out a spatial correlation between the magnetoencephalography measurement and the magnetic resonance imaging measurement, so that registration between the magnetoencephalography measurement and the positron emission tomography measurement results. | 2009-01-15 |
20090018432 | METHODS AND APPARATUS FOR IMAGING WITH MAGNETIC INDUCTION - An apparatus includes a magnetic energy source to provide a magnetic signal and a detector to detect an acoustic energy signal from a sample stimulated by the magnetic energy signal. A method includes applying a magnetic signal to a biological sample, detecting an acoustic signal from the sample, and processing the acoustic signal to determine the electrical impedance distribution of the sample, and identify disease in the biological sample. A method includes applying a magnetic signal to a sample, detecting a magnetic or electrical signal within the sample, and processing the magnetic or electrical signal to reconstruct electrical impedance distribution of the sample. | 2009-01-15 |
20090018433 | MAGNETIC RESONANCE IMAGING APPARATUS AND MAGNETIC RESONANCE IMAGING METHOD - A magnetic resonance imaging apparatus includes an acoustic control unit and an image data acquisition unit. The acoustic control unit applies a gradient magnetic field for controlling a sound in synchronized with a signal representing a respiratory body motion. The image data acquisition unit acquires imaging data by imaging subsequently to controlling the sound and generates image data based on the imaging data. | 2009-01-15 |
20090018434 | POSITION DETECTION APPARATUS AND MEDICAL-DEVICE-POSITION DETECTION SYSTEM - A position detection apparatus and a medical-device-position detection system that have improved position detection accuracy are provided by setting high amplification for the position detection apparatus. The position detection apparatus includes a circuit that has at least one embedded coil ( | 2009-01-15 |
20090018435 | Method and apparatus for reconstructing images of moving structures based on temporal data - A method for reconstructing images of structures undergoing physiological motion comprises acquiring a first volume of data over a first motion cycle. The first volume comprises a first overlap volume. A second volume of data is acquired over a second motion cycle and comprises a second overlap volume. The first and second overlap volumes comprise like anatomical regions with respect to each other. A reconstructed volume of data is formed based on temporal data within the first and second overlap volumes. | 2009-01-15 |
20090018436 | OPTICAL COHERENCE TOMOGRAPHY - A method of determining a disease state of an animal by imaging a sample of at least a portion of a tissue of the animal by optical coherence tomography scanning and comparing optical coherence tomographical scanned image the histopathological images of a tissue type of the animal at various stages of disease state stored in a histopathological image database. | 2009-01-15 |
20090018437 | Radiographic imaging method and apparatus - A reference frame is described for use in a radiographic procedure. The reference frame is positionable relative to a joint or bone to be imaged, and is radio-transparent. The frame has embedded or affixed thereto a plurality of computer recognizable radio opaque markers. A method of obtaining three dimensional images of bones and joints using the frame is described. | 2009-01-15 |
20090018438 | Image Derived Input Function For PET Lung Assessment - An input function indicative of a time-activity curve in pulmonary arterial plasma is produced from a series of PET image frames in lieu of manual blood sampling. Two manually acquired blood samples are input along with pixel values of a blood pool region of interest (ROI) in the PET image frames into a two-parameter model of the ROI's time-activity curve. In an iterative process the model converges to accurately indicate the amount of | 2009-01-15 |
20090018439 | Marker delivery divice with releasable plug - The invention is directed to marker delivery devices and methods of using such devices. The delivery devices embodying features of the invention include a delivery cannula with a discharge opening and a releasable plug disposed in the inner lumen of the delivery cannula so as to at least partially occlude the discharge opening. The releasable plug prevents ingress of tissue, body fluids and the like into the bore of the tube, and prevents the premature discharge of any markers proximal to the releasable plug from passing through the discharge opening before the distal end of the cannula is properly positioned at a desired location within a patient's body. The releasable plug preferably has an MRI detectable element. Preferably, at least one remotely detectable marker mass is provided in the inner lumen of the cannula proximal to the releasable plug. | 2009-01-15 |
20090018440 | Medical diagnostic imaging with hardware generated region of interest border - A system and method for generating a border of a region of interest of an image, such as a medical image, are disclosed. Imaging data is acquired for generation of an image. A region of interest of the image is determined. A display value is allocated to a plurality of pixels, respectively, based on color or tissue information from the imaging data. If at least one pixel corresponds to a border of the region of interest, a border value is allocated to the at least one pixel substantially at the same time as when the display value is allocated. The image having the border of the region of interest is displayed. | 2009-01-15 |
20090018441 | Medical diagnostic ultrasound scanning and video synchronization - Real-time scanning and display of images is synchronized for ultrasound imaging. The scanning rate requirements for obtaining a frame of ultrasound data are determined. The video rate for imaging is adjusted as a function of the scanning rate. | 2009-01-15 |
20090018442 | Diagnostic medical ultrasound system having clock synchronized power supply - A system and method is disclosed for minimizing image artifacts, or the effect thereof, of electrical noise/interference caused by switch-mode power supplies of a diagnostic medical imaging system, such as a diagnostic medical ultrasound system. In one embodiment, one or more switch mode power supplies capable of being synchronized to an external clock signal are utilized to power the ultrasound system. The clock signal to the power supplies is provided by the system, generated, or otherwise derived from, the clock signal used by the imaging components, and phase-synchronized to the transmit and receive events of the imaging system. In this way, noise generated by the power supplies is synchronized with the imaging processes and, at least, will appear as a substantially constant artifact in the diagnostic images, allowing it to be readily ignored by a user or automatically removed therefrom. | 2009-01-15 |
20090018443 | System for generating multiple beams from a single receive event - A system and method for storing imaging information of multiple receive events and/or for generating a plurality of beams from a single receive event are disclosed. A transducer has a plurality of elements and is operable to receive a first acoustic signal from a first receive event and a second acoustic signal from a second receive event. A memory is in communication with the transducer to receive element data from the plurality of elements. The memory is operable in a first section and a second section. The memory is further operable to store first and second imaging data in the first and second sections, respectively. The first and second imaging data is based on the first and second acoustic signals, respectively. | 2009-01-15 |