02nd week of 2012 patent applcation highlights part 47 |
Patent application number | Title | Published |
20120010400 | DUALLY SUBSTITUTED ZINC PHTHALOCYANINE COMPOSITION, PROCESS OF PREPARING THE SAME AND USE THEREOF - The invention discloses a pharmaceutical composition used in photodynamic therapy for cancer or precancerous lesions. The composition includes four isomers of zinc phthalocyanine. Furthermore, this invention also provides an industrial chromatography preparation process. The composition is synthesized by separating 10 cis-isomers from disulfonic acid diphthaloyl iminomethyl zinc phthalocyanine, and then separating among them 4 isomers with significant amphiphilic property. It is evident that the composition of the invention shows improved performance compared to compositions containing those 10 cis-isomers. | 2012-01-12 |
20120010401 | METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE - An industrially advantageous method for producing a 1,5-benzodiazepine compound is provided. | 2012-01-12 |
20120010402 | CGRP Receptor Antagonists - The disclosure generally relates to the novel compounds of formula I, including their salts, which are CGRP receptor antagonists. The disclosure also relates to pharmaceutical compositions and methods for using the compounds in the treatment of CGRP related disorders including migraine and other headaches, neurogenic vasodilation, neurogenic inflammation, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases such as asthma, and chronic obstructive pulmonary disease (COPD). | 2012-01-12 |
20120010403 | FLUOROBORON COMPOUND, AMINOMETHYLATING AGENT FOR AROMATIC RING MADE OF THE SAME, AND PRODUCTION METHOD OF COMPOUND CONTAINING AMINOMETHYL AROMATIC RING USING AMINOMETHYLATING AGENT - A production method of a compound containing a primary, secondary, or tertiary aminomethyl aromatic ring of the present invention includes: using a fluoroboron compound or a dimer thereof, or solvates thereof, which are represented by a formula (I): | 2012-01-12 |
20120010404 | OXAZINE DYES WITH IMPROVED AQUEOUS SOLUBILITY - The present invention provides oxazine dyes, processes for preparing the oxazine dyes, intermediates that may be utilized in the processes for preparing the oxazine dyes, and methods for using the oxazine dyes. | 2012-01-12 |
20120010405 | OPTICALLY ACTIVE 3-AMINO-2,5-DIOXOPYRROLIDINE-3-CARBOXYLATE, PROCESS FOR PRODUCTION OF THE COMPOUND, AND USE OF THE COMPOUND - The present invention provides a compound of the formula (III): | 2012-01-12 |
20120010406 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY - Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK 2 and JAK3, are therapeutically useful. | 2012-01-12 |
20120010407 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY - Disclosed are compounds of formula I, compositions containing them, and methods of use for the compounds and compositions in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK 2 and JAK3, are therapeutically useful. | 2012-01-12 |
20120010408 | Method for Preparing Acyclovir 2/3 Hydrate - Preparation of acyclovir 2/3 hydrate comprises mixing acyclovir with water at weight ratio of 1:5˜50, dissolving at 50˜100° C., filtering, cooling filtrate at 0˜30° C. to precipitate crystal, collecting the crystal by filtration, and drying the crystal at 0˜150° C. for 0.5˜24 hours to obtain acyclovir 2/3 hydrate. The preparation process is simple and suitable for industrial production. The prepared product has good and stable crystal form. | 2012-01-12 |
20120010409 | IMPROVED CHEMICAL SYNTHESIS OF DIAZAINDOLES BY CHICHIBABIN CYCLIZATION - An improved synthesis method for making diazaindoles using a Chichibabin cyclization is disclosed. In particular, this method is useful for making the compound of Formula I. | 2012-01-12 |
20120010410 | (2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE AND SALTS THEREOF - The present invention relates to a process for the preparation of compounds which are therapeutically active in the central nervous system. | 2012-01-12 |
20120010411 | MODIFIED SURFACE - The present invention relates to modified surfaces. The surfaces comprise an inorganic material on which a phosphinic acid derivative is adsorbed. The phosphinic acid thus turns out to be a new anchoring group useful for surface derivatisation. The invention has many applications for photoelectric conversion devices, batteries, capacitors, electrochromic displays, chemical sensors, biological sensors, light emitting diodes, electrodes, semiconductors, separation membranes, selective adsorbents, adsorbents for HPLC, catalysts, implants, nanoparticles, antiadhesives, and anticorrosion coatings, for example. | 2012-01-12 |
20120010412 | Process for the Synthesis of Substituted Morphinans - The present invention relates to a process for the synthesis of a compound of formula I: | 2012-01-12 |
20120010413 | Process for the Preparation of Pyrido [2,1-a] Isoquinoline Derivatives by Catalytic Asymmetric Hydrogenation of an Enamine - The invention relates to a process for the preparation of pyrido[2,1-a] isoquinoline derivatives of the formula | 2012-01-12 |
20120010414 | GLYCINE TRANSPORTER INHIBITING SUBSTANCES - The present invention aims to provide novel compounds of formula [I] or pharmaceutically acceptable salts thereof that are based on a glycine uptake inhibiting action and which are useful in the prevention or treatment of such diseases as schizophrenia, Alzheimer's disease, cognitive dysfunction, dementia, anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsory disorder, social anxiety disorder, posttraumatic stress disorder, specific phobia, acute stress disorder, etc.), depression, drug addiction, spasm, tremor, and sleep disorder: | 2012-01-12 |
20120010415 | PROCESS FOR THE PREPARATION OF 6-(7-((1-AMINOCYCLOPROPYL)METHOXY)-6-METHOXYQUINOLIN-4-YLOXY)-N-METHYL-1-- NAPHTHAMIDE AND SYNTHETIC INTERMEDIATES THEREOF - A process for the preparation in high yields and purity of the compound 6-(7-4(1-aminocyclopropyl)methoxy)-6-methoxyquinolin-4-yloxy)-N-methyl-1-naphthamide of formula (I) and of the pharmaceutically acceptable salts thereof is described. The process has various advantages over those previously described, in particular it avoids the use of acyl azide intermediates and their Curtius rearrangement. Novel intermediates useful for the preparation of compound (I) are also described. | 2012-01-12 |
20120010416 | PYRROLIDINONE BENZENESULFONAMIDE DERIVATIVES AS MODULATORS OF ION CHANNELS FOR THE TREATMENT OF PAIN - The present invention relates to heterocyclic derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 2012-01-12 |
20120010417 | METHOD FOR PRODUCING ALCOHOL COMPOUND - A method for producing an alcohol compound, wherein a carboxylic acid ester compound is reduced with hydrogen in the presence of a ruthenium complex which is obtained by reacting an imidazolium salt (A) having at least one optionally substituted amino group with a ruthenium compound (B) in the presence of a base (C). | 2012-01-12 |
20120010418 | Process for Making N-Hydroxy-3[4-[[[2-(2methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2- -propenamide and Starting Materials Therefor - N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2E-2-propenamide and starting materials therefore are prepared by new synthetic methods. | 2012-01-12 |
20120010419 | METHOD FOR PRODUCING 1,6-HEXANEDIOL AND CAPROLACTONE - The invention relates to a process for preparing 1,6-hexanediol and caprolactone, preferably with at least 99.5% purity, which are especially virtually free of 1,4-cyclohexanediols, from a carboxylic acid mixture which is obtained as a by-product of the catalytic oxidation of cyclohexane to cyclohexanone/cyclohexanol with oxygen or oxygen-comprising gases and by water extraction of the reaction mixture, by hydrogenating the carboxylic acid mixture, esterifying and hydrogenating a substream to hexanediol and cyclizing 6-hydroxycaproic ester, the 1,4-cyclohexanediols being removed either in the course of fractionation of the esterification mixture or last from the caprolactone. | 2012-01-12 |
20120010420 | PROCESS FOR PRODUCING AN ORGANIC COMPOUND - Process for producing a chlorohydrin by reaction between a multihydroxylated-aliphatic hydrocarbon, an ester of a multihydroxylated-aliphatic hydrocarbon, or a mixture thereof, and a chlorinating agent, according to which the multihydroxylated-aliphatic hydrocarbon, the ester of a multihydroxylated-aliphatic hydrocarbon, or the mixture thereof used contains at least one solid or dissolved metal salt, the process comprising a separation operation to remove at least part of the metal salt. | 2012-01-12 |
20120010421 | PROCESS FOR SYNTHESIZING BRIDGED CYCLOPENTADIENYL-INDENYL METALLOCENES - The present invention provides methods of making bridged cyclopentadienyl-indenyl metallocene compounds. Generally, these methods can be conducted without the use of a fine purification process such as distillation, chromatography, and crystallization. | 2012-01-12 |
20120010422 | METHOD FOR PRODUCING HYDROCARBON OXYSILICON COMPOUNDS - The invention relates to a method for producing silicon compounds (A) having hydrocarbon oxy-groups that have at least one unit of the general formula (1) H | 2012-01-12 |
20120010423 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon - A process for preparing a detergent alcohol mixture comprising the steps of providing one or more poly-branched poly-olefins, wherein the poly-branched poly-olefins must contain one non-branched terminal olefin and one or more additional branched olefins in the molecule; hydroformylating said poly-branched poly-olefins to produce a poly-branched olefin containing aldehyde product with one or more olefins or mixture thereof; reducing the aldehyde product of step (b) in the presence of hydrogen and a hydrogenation catalyst to form a poly-branched detergent alcohol mixture; and removing said poly-branched alcohol mixture from said catalyst and branched aldehydes, alcohols and surfactants produced from the products of this process. | 2012-01-12 |
20120010424 | LPA Receptor Agonists and Antagonists - Disclosed are compounds according to formula (I) as well as pharmaceutical compositions which include those compounds. Also disclosed are methods of using such compounds, which have activity as agonists or as antagonists of LPA receptors; such methods including treating cancer, producing radioprotection and/or radiomitigation, enhancing cell proliferation, treating a wound, treating apoptosis or preserving or restoring function in a cell, tissue, or organ, culturing cells, preserving organ or tissue function, and treating a dermato logical condition. | 2012-01-12 |
20120010425 | SYNTHESIS OF ACYLOXYALKYL CARBAMATE PRODRUGS AND INTERMEDIATES THEREOF - Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described. | 2012-01-12 |
20120010426 | Processes Related to the Hydroformylation of Butenes - Mixed butene streams containing butene-1 and isobutylene and optionally butene-2 are hydroformylated under conditions that hydroformylates all the monomers to yield a mixture of valeraldehydes | 2012-01-12 |
20120010427 | URETHANE COMPOUND AND METHOD FOR PRODUCING THE SAME, AND ISOCYANATE AND METHOD FOR PRODUCING THE SAME - A method for producing urethane compounds includes allowing a primary amine, a urea and/or an N-unsubstituted carbamate, and an alcohol to react in the presence of a compound containing a noncoordinating anion and a metal atom as a catalyst. | 2012-01-12 |
20120010428 | PROCESS FOR THE PREPARATION OF SULFOMATE-CARBOXYLATE DERIVATIVES - Disclosed is a process for the preparation of Compound (III), salt or solvate thereof by reacting Compound (I), salt or solvate thereof with Compound (II) in a toluene solvent in the presence of an additive such as water or an alcohol. Also disclosed is a process for the preparation of Compound (IV) comprising hydrolyzing the obtained Compound (III) if necessary, and then oxidizing. | 2012-01-12 |
20120010429 | SEPARATION PROCESS - The present invention relates to a method of separating betaine and at least one other component from a sugar beet based fermentation solution. The invention is based on the use of a combination of SAC resins and WAC resins in a specific order and in specified proportions in a chromatographic SMB separation system. The chromatographic separation system is preferably a single integrated SMB system comprising both SAC and WAC resin beds. | 2012-01-12 |
20120010430 | METERING RING - The present invention relates to an apparatus for metering flowable media or gases, and to the use thereof. | 2012-01-12 |
20120010431 | METHOD FOR PRODUCING 1-ADAMANTYL TRIMETHYLAMMONIUM HYDROXIDE - The present invention relates to a process for preparing 1-adamantyltrimethyl-ammonium hydroxide. | 2012-01-12 |
20120010432 | Specific Branched Aldehydes, Alcohols, Surfactants, and Consumer Products Based Thereon - A process for preparing a detergent alcohol mixture comprising the steps of providing one or more poly-branched poly-olefins, wherein the poly-branched poly-olefins must contain one non-branched terminal olefin and one or more additional branched olefins in the molecule; hydroformylating said poly-branched poly-olefins to produce a poly-branched olefin containing aldehyde product with one or more olefins or mixture thereof; reducing the aldehyde product of step (b) in the presence of hydrogen and a hydrogenation catalyst to form a poly-branched detergent alcohol mixture; and removing said poly-branched alcohol mixture from said catalyst and branched aldehydes, alcohols and surfactants produced from the products of this process. | 2012-01-12 |
20120010433 | DEVICE AND PROCESS FOR SOLID/LIQUID SEPARATION OF SOLID-LIQUID SUSPENSIONS - In a device and a process for continuous solid/liquid separation (filtration) of solid-liquid suspensions on moving filters, for example on rotating drum filters or belt filters, the active filtering layer contains a woven fabric material composed of synthetic fibres, which has an enhanced filtrate permeability and also an enhanced thermal stability with improved dimensional stability, and also improved mechanical strength compared with polypropylene fibres. | 2012-01-12 |
20120010434 | PROCESS FOR PRODUCING BISPHENOL COMPOUND - Provided is a process for producing a bisphenol compound stably at a high conversion and with high selectivity over a long period. A process for producing a bisphenol compound by feeding a phenol compound and a carbonyl compound continuously to a reactor packed with an acid catalyst, characterized in that the acid catalyst is a sulfonic-acid-form cation-exchange resin in which part of the sulfo groups have been modified with at least any one of 2-pyridylalkanethiol compounds and 3-pyridylalkanethiol compounds. | 2012-01-12 |
20120010435 | METHOD FOR ISOLATING DI-TRIMETHYLOL PROPANE - The present invention relates to a method for isolating ditrimethylol propane from secondary trimethylol propane production streams. | 2012-01-12 |
20120010436 | Separation of Vapor Crude Alcohol Product - Recovery of alcohol, in particular ethanol, by separating a vapor crude alcohol product obtained from the hydrogenation of acetic acid using a low energy process. The vapor crude ethanol product is separated in a column to produce a distillate stream comprising ethanol and at least one non-condensable gas. The vapor crude ethanol product may pass through a membrane before the first distillation column to separate the at least one non-condensable gas from the ethanol. The ethanol product is subsequently recovered from the distillate stream. | 2012-01-12 |
20120010437 | Liquid Esterification For The Production Of Alcohols - Purifying and/or recovery of ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid. Separation and purification processes of crude ethanol mixture are employed to allow recovery of ethanol and remove impurities. In addition, the process involves returning acetaldehyde separated from the crude ethanol product to the reactor. | 2012-01-12 |
20120010438 | Reduced Energy Alcohol Separation Process - Recovery of alcohols, in particular ethanol, from a crude ethanol product obtained from the hydrogenation of acetic acid using a reduced energy process. The crude ethanol product may be fed to a distillation column in which a substantial portion of the water is removed with the acetic acid in the residue. The ethanol product is obtained from the distillate. | 2012-01-12 |
20120010439 | PROCESS FOR RECOVERING ALCOHOL PRODUCED BY HYDROGENATING AN ACETIC ACID FEED STREAM COMPRISING WATER - Purifying and/or recovery of ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid from an feed stream comprising water. The presence of water does not significantly impact acid conversion or selectivity to ethanol. Further the addition of water allows for improved recovery of ethanol. | 2012-01-12 |
20120010440 | Separating Ethanol and Ethyl Acetate Under Low Pressure Conditions - A crude ethanol product obtained from the hydrogenation of acetic acid comprises ethanol and ethyl acetate. Using a distillation column operated at a pressure of from 0.1 to 100 kPa, the ethyl acetate and ethanol may be effectively separated. In addition, maintaining the amount of water that is fed to the distillation column to an amount less than 10 wt. %, based on the weight of all components fed to the distillation column, provides an energy benefit. | 2012-01-12 |
20120010441 | PROCESS FOR RECYCLING GAS FROM ACETIC ACID HYDROGENATION - Monitoring and recycling gases from acetic acid hydrogenation reaction to maintain a constant pressure in the hydrogenation reaction system. Purging of the vapor stream comprising hydrogen may be limited or reduced. Further purging of the by-product may be from the dissolved by-product gases. | 2012-01-12 |
20120010442 | PROCESS FOR RECOVERING ETHANOL WITH SIDEDRAWS TO REGULATE C3+ ALCOHOLS CONCENTRATIONS - Purification and/or recovery of ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid. Separation and purification processes of a crude ethanol mixture are employed to allow recovery of ethanol and remove impurities. In particular, the process involves one or more sidedraws to regulate C | 2012-01-12 |
20120010443 | Esterification Of Vapor Crude Product In The Production Of Alcohols - Ethanol production process for recovering ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid. Ethanol recovery is improved by esterifying a vapor crude ethanol product to reduce unreacted acetic acid concentration. | 2012-01-12 |
20120010444 | Alcohol Production Process with Impurity Removal - A method of removing impurities, such as halogens, sulfurs, and corrosion metal impurities, in an ethanol production process. Ion exchange resins may be used to remove these impurities from acetic acid feed streams and recycle streams that comprise unreacted acetic acid. | 2012-01-12 |
20120010445 | Low Energy Alcohol Recovery Processes - Recovery of ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid using various combinations of membranes and/or distillation columns. | 2012-01-12 |
20120010446 | Hydrogenolysis of Ethyl Acetate in Alcohol Separation Processes - Recovery of ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid and by reacting a portion of the crude ethanol product or one or more derivative streams containing ethyl acetate obtained therefrom in the presence of hydrogen, via hydrogenolysis. The one or more derivative streams comprise ethyl acetate that are reacted in via hydrogenolysis form additional ethanol that may be directly or indirectly fed to the separation zone or the hydrogenation reactor. | 2012-01-12 |
20120010447 | Weak Acid Recovery System for Ethanol Separation Processes - Recovery of ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid and recovery of unreacted acetic acid from a weak acid stream. The unreacted acetic acid may be recovered as a dry acetic acid composition and may be directly or indirectly fed to the hydrogenation reactor. | 2012-01-12 |
20120010448 | Finishing Reactor for Purifying Ethanol - A process for purifying ethanol by using a finishing reactor to remove impurities, such as ethyl acetate, acetaldehyde, acetic acid, and diethyl acetal, present in ethanol after distilling a crude product from a hydrogenation reactor. The finishing reactor may reduce the impurities in the presence of hydrogen and a catalyst or may hydrolyze the impurities. | 2012-01-12 |
20120010449 | SEPARATION OF R-1233 FROM HYDROGEN FLUORIDE - The invention relates to a process for separating monochloro-trifluoropropenes such as HCFC-1233 from azeotrope or azeotrope like combinations with HF. The process employs a cold, liquid phase separations and multiple azeotropic distillation trains. | 2012-01-12 |
20120010450 | HYBRID SYSTEM AND PROCESS FOR CONVERTING WHOLE TIRES AND OTHER SOLID CARBON MATERIALS INTO RECLAIMABLE AND REUSABLE COMPONENTS - A system and method of converting tires or other solid carbon based material is disclosed, wherein the system and method includes providing a chamber, feeding tires or other solid carbon based material or both into the chamber, rotating the chamber and heating and reducing the material in the chamber, collecting solid residue from the chamber, collecting vapor from the chamber, and converting vapor collected from the chamber to a liquid. The chamber has an interior surface and can include one or more ribs on the interior surface for rotating and tumbling the material in the chamber while heating the material. In another embodiment, wherein the material includes tires, the system and method includes rotating and heating the tires in the chamber causing the tires to collapse and liquefy, exposing the metal in the tires which aids in grinding the carbon material in the tires as they tumble, collecting solid residue, for example, tire carbons, such as carbon black, and collecting vapor, for example, vaporized oil, and benzene and methane gas from the chamber and converting the oil to, for example, No. 2 to No. 6 fuel oil. In yet another embodiment, the method includes heating the chamber to a temperature from about 500° F. to about 1000° F. using one or more low temperature gases reclaimed from the material. | 2012-01-12 |
20120010451 | PROCESS FOR OBTAINING HIGH-PURITY 1-BUTENE FROM C4 HYDROCARBON MIXTURES - A process is described for obtaining high-purity 1-butene starting from C | 2012-01-12 |
20120010452 | HETEROGENEOUS SUPPORTS FOR HOMOGENEOUS CATALYSTS - A method of making a heterogenously supported catalyst useful in dimerization, oligomerization or polymerization is provided in which a catalyst precursor containing a metal and an aromatic group are alkylated onto an oligomeric support having at least one terminal unsaturated group by Friedel Crafts alkylation. | 2012-01-12 |
20120010453 | OLEFIN PRODUCTION PROCESS - A novel olefin production process is provided which can be established as an industrial and practical process capable of producing olefins by directly reacting a ketone and hydrogen in a single reaction step. In particular, a novel olefin production process is provided in which propylene is obtained with high selectivity by directly reacting acetone and hydrogen. | 2012-01-12 |
20120010454 | SYSTEM AND METHOD FOR HYPERTHERMIC TUMOR TREATMENT - A system to induce hyperthermia in a selected portion of the body utilizes permanent magnets mounted on a variable speed motor. A conductive button is positioned at a location proximate the target tissue to be heated, such as a tumor. The magnetic rotor assembly is positioned at a selected distance from the conductive button and rotated at a desired frequency to produce a changing permanent magnetic field that induces an eddy current on the surface of the conductive button. A temperature sensor may be positioned near the conductive button as a feedback mechanism to a control circuit. At higher magnetic polarity frequencies, the conductive button may be implemented in the form of metallic nanoparticles. In this embodiment, the nanoparticles may include molecular elements that selectively bind with the target tissue and thereby accumulate at the target tissue prior to the introduction of the rotating magnetic field. | 2012-01-12 |
20120010455 | Attachment Method - Preparing the heart for connection with a ventricular assist device (VAD) can include attaching an attachment ring to a ventricular apex of the heart. The attachment ring optionally includes a seal or a valve to allow the procedure to be performed with or without a heart-lung bypass. A valve can be temporarily attached to the attachment ring. Tissue is removed from the ventricular apex through the attachment ring to form a hole through which an inflow conduit of the VAD can be inserted. A slit can first be made in the ventricular apex to facilitate removal of the tissue. A clamp can be closed around the attachment ring to secure the inflow conduit. | 2012-01-12 |
20120010456 | ADJUSTABLE SURGICAL SLING - The invention, in one embodiment, is directed to systems and methods for adjusting support to an anatomical location using an expandable chamber. | 2012-01-12 |
20120010457 | Prolapse Repair - Surgical instruments for prolapse repair are disclosed. The surgical instruments have straight portions and helical portions. | 2012-01-12 |
20120010458 | Transobturator Surgical Articles and Methods - Surgical articles, implants and components suitable for a transobturator surgical procedure are described. | 2012-01-12 |
20120010459 | ASSEMBLY AND METHOD FOR AUTOMATICALLY CONTROLLING PRESSURE FOR A GASTRIC BAND - An elastic bladder is provided that is in constant fluid communication with the expandable balloon portion of a gastric band in order to automatically and continuously adjust the gastric band. The fluid pressure between the bladder and the balloon portion of the gastric band automatically and continuously adjusts so that there is no lasting pressure differential between the bladder and the expandable balloon. As the level of restriction imparted by the gastric band on the stomach of the patient changes, fluid from the bladder automatically and substantially instantaneously flows to or from the expandable balloon portion of the gastric band thereby maintaining neutral fluid pressure equilibrium between the bladder and the balloon and automatically adjusting the band to the correct level of restriction to keep the patient in the optimum zone for weight loss. | 2012-01-12 |
20120010460 | TISSUE DISPLACING METHOD - An organ displacing method implemented for performing a procedure in a patient's body cavity, the method includes a gravitational movement step in which the body position of the patient is changed, whereby surrounding organs adjacent to a hollow organ are moved in a primary direction by gravity; and a non-gravitational movement step in which, by using a medical instrument inserted into the hollow organ, the hollow organ is moved in a secondary direction where the hollow organ is separated from the surrounding organs. | 2012-01-12 |
20120010461 | METHODS AND DEVICES FOR TISSUE GRASPING AND ASSESSMENT - Devices, systems and methods are provided for stabilizing and grasping tissues such as valve leaflets, assessing the grasp of these tissues, approximating and fixating the tissues, and assessing the fixation of the tissues to treat cardiac valve regurgitation, particularly mitral valve regurgitation. | 2012-01-12 |
20120010462 | SNAP FIT SLING ANCHOR SYSTEM AND RELATED METHODS - The invention provides, in various embodiments, systems, devices and methods relating to employing soft tissue anchors in combination with an implantable sling to treat urinary incontinence. | 2012-01-12 |
20120010463 | INSTRUMENT AND METHOD FOR REMOTELY MANIPULATING A TISSUE STRUCTURE - A retractor and a surgical tool are posittioned within a cannula, and a dissection cradle of the retractor is positioned at the distal end of the cannula. The retractor includes a dissection cradle that is resiliently supported along an axis skewed relative to the axis of the cannula. The dissection cradle, in operation, is extended to cradle the target vessel, and the retractor may be fully extended to urge the vessel away from the axis of the cannula to isolate a side branch for exposure to a surgical tool. The retractor includes a hollow support and a spray nozzle disposed in the distal end of the retractor to form an irrigation system and lens washer that can be selectively positioned to direct the spray of irrigation fluid at a remote surgical site or at an endoscopic lens. | 2012-01-12 |
20120010464 | ACCESS SYSTEM WITH REMOVABLE OUTFLOW CHANNEL - A surgical access device can comprise a working channel providing a first lumen having an axial opening for insertion of a surgical instrument having an outflow channel, the first lumen having a fluid inlet for allowing fluid flow through the working channel and into the body, wherein fluid flows out of the body through the outflow channel of the surgical instrument; and a optical channel providing a second lumen for a visualization element and a light source, wherein the working channel comprises a larger cross-sectional area than the cross-sectional area of the optical channel. The surgical access device can further comprise a seal apparatus coupled to the working channel and configured to receive the surgical instrument, the seal apparatus comprising a first seal portion and a second seal portion, the first seal portion configured to close the fluid path into the seal apparatus, and the second seal portion configured to form a seal with the surgical instrument. | 2012-01-12 |
20120010465 | ENDOSCOPE APPARATUS - A first irradiation portion that radiates white light onto a subject, a second irradiation portion that radiates narrow bandwidth light having a narrower wavelength bandwidth than the white light, and an observation window used to observe the subject are respectively disposed on a leading end surface of an endoscope insertion portion. Each of the first and second irradiation portions includes a pair of irradiation windows for emitting light therefrom. A straight line passing through a center point of the observation window and bisecting the leading end surface is defined as a boundary line. The pair of irradiation windows of the first irradiation portion are disposed on both sides of the boundary line. The pair of irradiation windows of the second irradiation portion are disposed on the both sides of the boundary line. Spectra of lights radiated from the irradiation windows of the second irradiation portion can be changed individually. | 2012-01-12 |
20120010466 | TRANSDUCER/SENSOR ASSEMBLY - An imaging transducer assembly is combined with a sensor of a medical positioning system, forming a transducer/sensor assembly. In one embodiment, the sensor includes a coil proximally coupled with the imaging transducer. A cable having first and second wires are proximally coupled to the coil. A non-conductive potting layer is wrapped around the coil. Traces are formed in the non-conductive potting layer that are used to electrically couple the imaging transducer with the first and second wires of the cable. | 2012-01-12 |
20120010467 | LARYNGEAL MASK AIRWAY DEVICE - The invention relates to a laryngeal mask airway device ( | 2012-01-12 |
20120010468 | SYSTEM OF DISPOSABLE CONTOURED SLEEVES FOR FLEXIBLE ENDOSCOPES - A system of for labeling and organizing de-contaminated and cleaned flexible endoscopes with coded one-use disposable sheaths. The sheaths are specifically contoured and coded for specific types of endoscopes. The endoscopes can only be removed from sheaths by tearing, slicing, cutting or otherwise breaking the sheaths open. This product system reduces the risk of patient to patient cross-contamination by labeling cleaned endoscopes for easy identification by medical care professionals. | 2012-01-12 |
20120010469 | CATHETER GUIDING TOOL - A catheter guiding tool includes a handle of the guiding tool, the handle including an inner cavity extending between a proximal end and a distal end of the handle; a flexible wire guide; a cover closing the proximal end of the handle, wherein the proximal end of the wire guide forms a coil spring, the coil spring being positioned in the inner cavity of the handle and held in rotation by the cover, the cover being solidary in rotation of the handle. | 2012-01-12 |
20120010470 | DEVICES AND METHODS FOR ANCHORING A TUBE - Devices and methods are provided for accessing a bodily opening that, among other things, are safe, reliable and repeatable. One embodiment of a device for anchoring to tissue includes an elongated tube and a magnet. The elongated tube has a proximal end opposite a distal end, and defines a central axis. The magnet is attached to the distal end of the elongated tube and has a magnetic field attractive to the magnetic material in the tissue. The magnet has an annular shape defining an aperture through which the elongated tube extends. | 2012-01-12 |
20120010471 | OVER DILATION - A device, system and method for dilating a patient during a minimally invasive surgical procedure is disclosed. A surgical dilation system includes a dilator having an outer tubular member and an inner tubular member sized to be movably received within an inside diameter of the outer tubular member. The outer tubular member includes a vertical slot running through a side of the outer tubular member. The inner tubular member has an upper portion and a lower portion. The retractor has a proximal end including at least one mounting member protruding outwardly from a side surface of the retractor and a distal end including at least one fanned blade protruding outwardly from the side surface. When the inner tubular member is oriented in a first position the vertical slot is in a closed state, when the inner tubular member is oriented in a second position the mounting member is permitted to travel downwardly a predetermined distance in the vertical slot, and when the inner tubular member is positioned in a third state the mounting member is permitted to freely travel through the vertical slot. | 2012-01-12 |
20120010472 | RETRACTOR FOR USE DURING RETROPERITONEAL LATERAL INSERTION OF SPINAL IMPLANTS - A method is disclosed for introducing a spinal disc implant into an intervertebral space of a subject. The subject is placed in a lateral position, and the anterior face of the spinal disc intervertebral space is accessed, between the L5 and S1 vertebrae, from an anterior and lateral retroperitoneal approach. An operative corridor to the anterior face of the spinal disc space is established by introducing a retractor instrument anterolaterally to the spinal disc space between the anterior superior iliac spine and the anterior inferior iliac spine. The damaged spinal disc contents are removed from the intervertebral space through the operative corridor, and the implant is advanced into the intervertebral space at an oblique angle and pivoted to position the implant substantially laterally within the intervertebral space. Elongated retractor and insertion instruments, as well as a modified disc implant, are also disclosed for carrying out the method. | 2012-01-12 |
20120010473 | Health and Wellness Tracker - A business method utilizing a health and wellness tracker for the optimization of the health program provided for the members of an organization. The present invention provides a wellness tracking service that prompts the members of the organization in predetermined time intervals for health activities. The health of the group of members are compiled into a report and analyzed by the organization for the adjustment and optimization of the health program for the member of the organization. | 2012-01-12 |
20120010474 | METHOD, SYSTEM AND COMPUTER PROGRAM FOR AUTOMATED INTERPRETATION OF MEASUREMENTS IN RESPONSE TO STIMULI - The invention relates to a system and a method for analysing with a temporal resolution below 160 milliseconds at least one response of a test person to at least one input stimulus. At least one input stimulus is provided to the test person and data representing the test person's response to this provided at least one input stimulus is obtained. From these data, at least one induced response pattern is determined in an automatic manner and at least one induced response pattern is identified. Optionally, the response pattern is interpreted and at least one induced response indicator is identified. The identified at least one induced response pattern and/or and at least one induced response indicator are synchronized to the presented at least one input stimulus. The synchronized at least one input stimulus and the determined at least one response pattern and/or at least one response indicator are presented in the same display and/or stored on the same means for storing. A database unit allowing the at least one input stimulus and/or the identified at least one induced response pattern to be stored and/or retrieved and/or compared to input stimuli and/or identified induced response patterns from analyses performed on the same test person and/or other test persons. The means for automatically determining comprises means for automatically analyzing the obtained data to identify at least one induced response pattern, or at least one feature thereof. | 2012-01-12 |
20120010475 | INTEGRATED DISPLAY AND CONTROL FOR MULTIPLE MODALITIES - A system and method of managing an integrated laboratory for diagnosing and treating a patient is described. The system is divided into a laboratory room and a cockpit control room. The cockpit control room has a plurality of workstations for display and control of the laboratory equipment, so that two operators may cooperate in operating the equipment without conflict. All of the needed data is displayed to each operator in a single display where the display area is divided by a predetermined selectable grid pattern. The equipment in the laboratory room and the cockpit control room connected by electrically isolated paths. A backup workstation is provided, where at least the essential laboratory equipment is connected using an independent electrically isolated path. | 2012-01-12 |
20120010476 | MEDICAL IMPLANT WITH SAFETY FEATURE - A medical implant and system comprising a safety feature for reducing the likelihood of damage caused to a user of the implant system by exposure of body tissue and fluids to electrical energy from a power source of the implant. In one aspect, the medical implant comprises a disconnect switch which, upon actuation in response to an event, isolates the power source to prevent exposure to the user. In another aspect, there is provided a hermaticity failure sensor which, upon detection of a rupture in a hermetic casing of the medical implant, generates a detection signal. | 2012-01-12 |
20120010477 | CONCENTRATION DETERMINATION APPARATUS, PROBE, CONCENTRATION DETERMINATION METHOD, AND PROGRAM - A concentration determination apparatus may determine a concentration of a target component in an arbitrary layer of an observed object including a plurality of light scattering medium layers. The concentration determination apparatus may include an irradiation unit, light scattering medium layer selection unit, a light receiving unit, a light intensity acquisition unit, an optical absorption coefficient calculation unit, and a concentration calculation unit. | 2012-01-12 |
20120010478 | Analyzing Physiological State for Fitness Exercise - A method, apparatus, and a computer program for monitoring a fitness exercise are described. A plurality of heart-rate variability values and a plurality of exertion parameter values are measured during an exercise measured. The heart rate variability values correlate with the exertion parameter values through a human physiological mechanism, and the exertion parameter values characterize the physical exertion of the exercise. A mathematical correspondence is then constructed from the plurality of measured heart rate variability values and associated exertion parameter values. The mathematical correspondence describes correlation between the heart rate variability values and the exertion parameter values and the user's physiological state during the exercise. Then, the physical exertion of the exercise is monitored by applying the mathematical correspondence. | 2012-01-12 |
20120010479 | METHOD, COMPUTER READABLE MEDIUM AND DEVICE FOR DETERMINING THE TEMPERATURE DISTRIBUTION IN A TISSUE - Example embodiments of the present invention relate to a method for determining the temperature distribution in a tissue to be ablated and/or in a body tissue of a patient containing the tissue to be ablated. The method includes determining at least one item of information relating to a blood flow associated with at least one of in the tissue to be ablated and in the body tissue containing the tissue to be ablated, such that the item of information originates from a perfusion measurement of at least one of the tissue to be ablated and the body tissue containing the tissue to be ablated. The method includes determining the temperature distribution in the tissue to be ablated and/or in the body tissue containing the tissue to be ablated taking into account the at least one item of information relating to the blood flow. | 2012-01-12 |
20120010480 | IN-VIVO INFORMATION ACQUIRING SYSTEM - An in-vivo information acquiring system includes a body-insertable apparatus that includes a magnetic field responding unit, acquires in-vivo information, and transmits the in-vivo information to the outside; a magnetic field generator that generates a magnetic field for the responding unit; a magnetic field control unit that controls a generation of the magnetic field; a receiving unit that receives the in-vivo information transmitted from the apparatus; a processing unit that processes the in-vivo information; a display unit that displays the processed in-vivo information on a screen; an alarm lamp that notifies a generation state of the magnetic field; and a control unit that controls light emission process of the lamp such that an operator who visually identifies the in-vivo information is less disturbed by the light. The control unit performs control such that the lamp emits light upon no magnetic field and stops the generation of light upon the magnetic field. | 2012-01-12 |
20120010481 | Systems, devices, and methods including implantable devices with anti-microbial properties - Systems, devices, methods, and compositions are described for providing an actively controllable implant configured to, for example, monitor, treat, or prevent microbial growth or adherence to the implant. | 2012-01-12 |
20120010482 | INSERTION SYSTEM - An insertion system for inserting a sensor into fatty tissue, comprising an insertion device and an insertion needle containing a sensor, wherein the insertion device comprises a holder for the insertion needle, and a piercing mechanism so as to move the holder, with the needle held by the same, in a feed direction for a puncture. The piercing mechanism changes the feed direction during the puncture so that, at the end of the puncture, an insertion needle held by the holder is oriented obliquely or perpendicular to the initial feed direction. Also provided are methods for controlling a needle moved by an insertion device. | 2012-01-12 |
20120010483 | INTRA-OPERATIVE USE OF FLUORESCENCE SPECTROSCOPY AND APPLICATIONS OF SAME - In one aspect, the present invention relates to a process for intra-operatively providing anatomical guidance in endocrine surgery. In one embodiment, the process includes the steps of illuminating tissues in the neck area of a living subject with a beam of light having a predetermined wavelength, obtaining Raman data from light scattered from the illuminated tissues, finding Raman signatures corresponding to thyroid or parathyroid tissues from the obtained Raman data, and identifying the thyroid or parathyroid tissues from the corresponding Raman signatures. | 2012-01-12 |
20120010484 | PHOTOBIOLOGICAL MEASURING DEVICE AND ANALYZING METHOD - A photobiological measuring device has a computing unit generating an unwanted component removal observation signal by removing the signal corresponding to the unwanted component from an observation signal. The computing unit is provided with: a mixing matrix making unit for separating observation signals into the products of a mixing matrix and independent component signals through independent component analysis; a power spectrum computing unit generating transformed independent component signals, which are functions of frequency and intensity, by Fourier transforming the independent component signals, which are functions of time and intensity, and computing power spectra in predetermined frequency bands of transformed independent component signals; and an unwanted component signal determining unit detecting the independent component signal corresponding to the unwanted component from among the independent component signals by comparing the power spectrum in a predetermined frequency band of each transformed independent component signal with a threshold. | 2012-01-12 |
20120010485 | Device for Detecting at Least One Vital Parameter of a Person in a Vehicle and Device for Monitoring at Least One Vital Parameter of a Person in a Vehicle - A device for detecting at least one vital parameter of a person in a vehicle is described, having: an optoelectronic sensor arrangement for detecting the at least one vital parameter by means of light remission, wherein the optoelectronic sensor arrangement has at least one light source and a light-sensitive element, and wherein the first light source and the light-sensitive element are arranged in a finger bed of an operating element of the vehicle, and wherein the finger bed is implemented to integrate a fingertip of the person flush in a sensor area of the finger bed in which the first light source and the light sensitive element are arranged. | 2012-01-12 |
20120010486 | SENSOR CHIP, AND MEASUREMENT DEVICE AND BLOOD TEST DEVICE IN WHICH THIS SENSOR CHIP IS USED - This sensor chip ( | 2012-01-12 |
20120010487 | SYSTEMS AND METHODS FOR MONITORING HEALTH AND DELIVERING DRUGS TRANSDERMALLY - The present invention pertains to a system and method for transdermal sampling, comprising: at least one sampler for retrieving and transferring at least one analyte obtained transdermally from the skin of a subject; at least one detector system for identifying and quantifying said at least one analyte; and at least one logic module for (i) receiving and storing input data from said at least one detector, (ii) relating the input data to other data obtained from the subject, (iii) displaying output information, (iv) transmitting the output information to another system, and (v) controlling the operation of said at least one sampler and at least one detector. | 2012-01-12 |
20120010488 | Method and apparatus for improving personnel safety and performance using logged and real-time vital sign monitoring - Group (including, without limitation, occupational work forces) safety and wellness monitoring utilizes baseline physiology testing and vital sign monitoring and sampling technologies. Aerobic capacity of individual members of a group is determined through initial baseline testing which results in an individual health risk assessment. Thereafter non-invasively observed and monitored during incremental work and exercise is commenced. Subsequent data collected is used for advance identification of personnel at risk of injury, such as during unexpected vital sign elevations that can signal early onset of fatigue and heat stress/dehydration prior to injury. | 2012-01-12 |
20120010489 | TEST METHOD AND TEST DEVICE FOR ANALYSING A BODY FLUID - There is provided a test method for analysing a body fluid in which a test tape is used in a test device in order to successively provide analytical test fields stored on the test tape, wherein body fluid is applied by a user to the test field provided at a time and the said test field is photometrically scanned using a measuring unit of the device to record measurement signals. In order to increase the measurement reliability, it is proposed that a control value is determined from a time-dependent and/or wavelength-dependent change in the measurement signals and that the measurement signals are processed as valid or discarded as erroneous depending on the control value. | 2012-01-12 |
20120010490 | Medical devices having flexible electrodes mounted thereon - Medical devices and systems comprising medical devices are provided. The kit includes a catheter-introducer comprising a shaft having a major lumen sized to receive a second medical device and an electrode mounted thereon and a catheter comprising an elongate body and at least two flexible electrode segments on the distal end. The shaft includes an inner liner and outer layer. The system comprises a first medical device having a shaft and an electroanatomical system imaging element mounted thereon and a second medical device having an elongate body and at least two flexible electrodes mounted on the distal end. The shaft has a major lumen sized to receive the second medical device. The system further comprises an electroanatomical navigation system configured to receive signals from the electroanatomical system imaging element and to determine a position of the electroanatomical system imaging element and/or monitor electrophysiological data. | 2012-01-12 |
20120010491 | System and Apparatus for Collecting Physiological Signals from a Plurality of Electrodes - A system and apparatus for obtaining physiological data from a patient. The system and apparatus comprising at least one electrode disposed to collect physiological data from the patient and an electrode connection device having a conductive array formed by a plurality of conductive regions and a plurality of nonconductive regions. The conductive regions are suitable to be connected to the at least one electrode. The electrode may be connected to a first conductive region of the electrode communication device and wherein upon movement by the patient or the conductive array, the electrode is connected to a second conductive region of the conductive array. | 2012-01-12 |
20120010492 | GARMENT TO FACILITATE ELECTRODE PLACEMENT FOR INTRAOPERATIVE MONITORING - A garment is provided with an electrode and indicia to facilitate placement of the garment. The indicia is used to orient the garment such that the electrode is placed in precise orientation with respect to a stimulation site to facilitate intraoperative monitoring during surgical procedures. | 2012-01-12 |
20120010493 | SYSTEMS AND METHODS OF 4D ELECTROMAGNETIC TOMOGRAPHIC (EMT) DIFFERENTIAL (DYNAMIC) FUSED IMAGING - Methods and systems for 4D electromagnetic tomographic differential (dynamic) fused imaging and mapping of electrical excitation of biological tissues. A plurality of electromagnetic field sources and detectors generate and detect an electromagnetic field domain in a target area. A biological tissue is positioned within the target area, and an electromagnetic field domain is generated via a selected plurality of sources. The field generated by each source is selectively characterized so that each of a selected plurality of detectors recognizes a source of field from the plurality of sources. The sources and detectors are controlled so that fields generated by the selected sources are received by the selected detectors after interacting with the tissue. Based on the field received at each detector, a complex interference (scattering) matrix is derived from the tissue-generated field, and anatomical and functional image information are reconstructed from this matrix. The anatomical information and functional information are fused for display. | 2012-01-12 |
20120010494 | OPTICAL THREE-DIMENSIONAL STRUCTURE MEASURING DEVICE AND STRUCTURE INFORMATION PROCESSING METHOD THEREFOR - An optical three-dimensional structure measuring device including: optical three-dimensional structure information storing device ( | 2012-01-12 |
20120010495 | Method For Generating MR Images And An Appropriately Designed Magnetic Resonance System - An embodiment of the invention relates to the generation of MR images of a volume section within an examination object by way of a magnetic resonance scanner. In at least one embodiment, the following steps are performed: generating at least one of the MR images; automatically performing a number of quality inspections on the at least one MR image; and, should one of these quality inspections fail, an action is automatically performed in order to improve a quality when generating more of the MR images. | 2012-01-12 |
20120010496 | MEDICAL IMAGE DIAGNOSIS APPARATUS AND A CONTROLLING METHOD - A medical image diagnosis apparatus according to the present embodiments includes a storage and an execution controller. The storage is configured to store therein a program for executing a plurality of processes contained in an image taking procedure or a plurality of processes contained in a post-processing procedure, while the processes are classified into a first group for which an input operation from an operator is received and a second group for which the input operation is not received, and the processes are associated with one another according to an order. The execution controller is configured to exercise control so that the processes are executed according to the order. When executing a process classified into the first group, the program displays information selected according to a purpose of the image taking procedure or the post-processing procedure, as an operation screen. | 2012-01-12 |
20120010497 | Single-Sided Magnetic Resonance Imaging System Suitable for Performing Magnetic Resonance Elastography - A unilateral magnetic resonance imaging (“MRI”) device ( | 2012-01-12 |
20120010498 | OPERATION SUPPORTING DEVICE, METHOD, AND PROGRAM - Surgical operation supporting apparatus and method is disclosed in which based on a high-definition tomographic images of an operation site produced before surgery, a three-dimensional model of the operation site is generated, and a surface of the operation site is optically measured during the surgical operation, and further, first position information that represents a three-dimensional position of each of points on the surface is acquired. An unexposed portion of the operation site is measured with ultrasonic waves during the surgical operation, and second position information that represents a three-dimensional position of each of points in the unexposed portion is acquired. Based on the first position information and the second position information, displacement and distortion at a portion whose three-dimensional position is not known in the three-dimensional model is estimated to obtain an estimated result. The three-dimensional model is re-corrected by use of a finite element method and the estimated result. | 2012-01-12 |
20120010499 | USE OF NANOPARTICLES FOR THE TREATMENT OF CANCER - The invention relates to the tracking of mesenchymal stem cells (MSCs) labeled with magnetic nanoparticles using magnetic resonance imaging (MRI) and the use of this method for the treatment of cancer. | 2012-01-12 |