01st week of 2013 patent applcation highlights part 60 |
Patent application number | Title | Published |
20130005910 | ACRYLIC PRESSURE-SENSITIVE ADHESIVE COMPOSITION FOR OPTICAL USE AND ACRYLIC PRESSURE-SENSITIVE ADHESIVE TAPE FOR OPTICAL USE - An acrylic pressure-sensitive adhesive composition for optical use includes: an acrylic polymer (A) that contains, as a monomer unit, a vinyl monomer having a nitrogen atom in its backbone and that does not substantially contain a carboxyl group-containing monomer; and a (meth)acrylic polymer (B) having a weight average molecular weight of 1000 or more and less than 30000. | 2013-01-03 |
20130005911 | ACRYLIC PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND ACRYLIC PRESSURE-SENSITIVE ADHESIVE TAPE - An acrylic pressure-sensitive adhesive composition contains: an acrylic polymer (A); and a (meth)acrylic polymer (B) that includes, as a monomer unit, a (meth)acrylic monomer having a tricyclic or higher alicyclic structure and that has a weight average molecular weight of 1000 or more and less than 30000. | 2013-01-03 |
20130005912 | High Melt Strength Polystyrene and Methods of Making Same - A method of making a styrenic composition having a high melt strength including combining a styrenic monomer and a second monomer to form a combined mixture and subjecting the combined mixture to polymerization to obtain a styrenic co-polymer, wherein the second monomer comprises a hydroxyl functional group and wherein the styrenic composition has a greater melt strength than that of general purpose polystyrene. | 2013-01-03 |
20130005913 | METHOD FOR TREATING THE ELASTOMER SURFACE OF A DEVICE FOR DISPENSING A FLUID PRODUCT - A treatment method for treating an elastomer surface of a fluid dispenser device, the method including the step of using chemical grafting to form a thin film on at least one support surface of at least one elastomer surface of the dispenser device, the thin film avoiding the elastomer surfaces sticking during the manufacturing and assembly stages. | 2013-01-03 |
20130005914 | STYRENE/ANHYDRIDE POLYMERIC MATERIAL AND GRAFT HAVING ENHANCED PROPERTIES - A polymeric material from the styrene family comprises macromolecular chains grafted by nitrogen-containing heterocyclic groups; wherein the macromolecular chains comprise a polymeric backbone to which a grafted agent is attached by at least one covalent bond, the grafting agent comprises, in a single molecule, one or more associative groups capable of being bound by hydrogen bonds, and one or more reactive groups capable of forming covalent bonds with the polymeric backbone, at least one of the associative groups of the modifier is an imidazolidone heterocyclic ring. The mean number of imidazolidone groups to be inserted into the macromolecular chains is dependent both on the mean mass of said chains and on the final properties to be imparted to the material. Objects such as tubes, films, plates, stiffenerss, bottles and containers can be made. | 2013-01-03 |
20130005915 | PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET - The present invention provides a pressure-sensitive adhesive composition excellent in the anti-foaming release property and high-temperature stress relaxation property, and a pressure-sensitive adhesive layer composed of the pressure-sensitive adhesive composition. The invention relates to a pressure-sensitive adhesive composition including an acrylic polymer which is formed from a monomer component including methyl methacrylate and has a glass transition temperature (Tg) of −40° C. or more, wherein the pressure-sensitive adhesive composition has a shear storage elastic modulus at 85° C. as measured by a dynamic viscoelasticity measurement of from 1×10 | 2013-01-03 |
20130005916 | PROCESS FOR THE PREPARATION OF LOW MOLECULAR WEIGHT HYDROGENATED NITRILE RUBBER - Pursuant to the invention a process for the production of hydrogenated nitrile rubber polymers having lower molecular weights and narrower molecular weight distributions than those known in the art in the is provided wherein the process is carried out in the presence of hydrogen and optionally at least one co-(olefin). The present invention further relates to the use of specific metal compounds in a process for the production of a hydrogenated nitrile rubber by simultaneous hydrogenation and metathesis of a nitrile rubber. | 2013-01-03 |
20130005917 | Process for producing chemically functionalized nano graphene materials - Provided in this invention is a process for producing chemically functionalized nano graphene materials, known as nano graphene platelets (NGPs), graphene nano sheets, or graphene nano ribbons. Subsequently, a polymer can be grafted to a functional group of the resulting functionalized graphene. In one preferred embodiment, the process comprises a step of mixing a starting nano graphene material having edges and two primary graphene surfaces, an azide or bi-radical compound, and an organic solvent in a reactor, and allowing a chemical reaction between the nano graphene material and the azide compound to proceed at a temperature for a length of time sufficient to produce the functionalized nano graphene material. | 2013-01-03 |
20130005918 | METHOD FOR PRODUCING POLYMERIC POLYAMINES - Polymeric polyamine is produced by polymerizing polyoxyalkylene-amine and a linker. The polyoxyalkylene-amine has a structural formula H | 2013-01-03 |
20130005919 | PROCESS FOR PRODUCING WATER-ABSORBING RESIN - The disclosed process for continuously producing a water-absorbing resin comprising a plurality of joined continuous steps; a polymerization step of polymerizing an aqueous unsaturated monomer solution, a drying step of drying a particulated water-containing gel-like crosslinked polymer obtained in a finely crushing step during the polymerization or after the polymerization, a pulverizing step after the drying, a classification step after the drying, and a surface treatment step for the water-absorbing resin powder after the classification step. In the process, with some of the above steps kept running, the other steps are interrupted, and subsequently all the steps are restarted. | 2013-01-03 |
20130005920 | METHOD FOR PRODUCING CNT-PI COMPLEX HAVING EMI SHIELDING EFFECTIVENESS - A CNT-PI complex primarily includes polyimide (PI) and carbon nanotubes (CNT) dispersed in the polyimide. The method for producing the CNT-PI complex first disperses carbon nanotubes in a solvent by adding a dispersant and using an ultrasonic oscillator. Then the carbon nanotubes dispersion is mixed with polyamic acid to give a CNT-PI dispersion. The CNT-PI dispersion is then dried to form a film or layer of the CNT-PI complex. The dispersant used in this invention is an ionic liquid including organic cations and inorganic anions. The produced CNT-PI complex possesses good electromagnetic shielding effectiveness and presents better networked structures and electrical conductivity. | 2013-01-03 |
20130005921 | FLUORINATED POLYESTER BLEND - A fluorinated polyester blend is prepared by melt blending a fluorovinyl ether functionalized polyester with a non-fluorinated polyester. The fluoroether functionalized polyester can be a homopolymer or a copolymer. The blend is useful for preparing fibers, yarns, fabrics, garments, carpets, and other shaped articles. The shaped articles exhibit durable soil, oil, and water repellency. | 2013-01-03 |
20130005922 | FIBERS AND YARNS FROM A FLUORINATED POLYESTER BLEND - Yarns comprising fibers comprising a fluorinated polyester blend are prepared by melt blending a fluorovinyl ether functionalized polyester with a non-fluorinated polyester. The fluoroether functionalized polyester can be a homopolymer or a copolymer. The yarns and fibers, and the textile and carpet goods produced therefrom, exhibit durable soil, oil, and water repellency. | 2013-01-03 |
20130005923 | PROCESS FOR GAS-PHASE POLYMERIZATION HAVING HIGH BED BULK DENSITY - The present invention relates to an improvement for gas-phase olefin polymerization process having relatively high bed bulk density. The improvement involves the use of mixed external electron donors when polymerizing propylene in a gas-phase reactor having a polymer bed with a bulk density greater than 128 kg/m | 2013-01-03 |
20130005924 | FLUORINATED COMPOUND AND FLUORINATED POLYMER - To provide a fluorinated compound having an R | 2013-01-03 |
20130005925 | AQUEOUS SOLUTION COMPRISING ACRYLIC ACID AND THE CONJUGATE BASE THEREOF - An aqueous solution containing 10% by weight of acrylic acid and its conjugate base. The solution further contains, based on the amount of acrylic acid and its conjugate base: at least 50 ppm of propionic acid and its conjugate base; at least 200 ppm of formic acid and its conjugate base; at least 3000 ppm of acetic acid and it conjugate base; at most 10 ppm of benzoic acid and its conjugate base; at most 10 ppm of maleic anhydride, maleic acid, and their conjugate bases; at most 10 ppm of phthalic anhydride, phthalic acid, and their conjugate bases; at most 50 ppm of acrolein; at most 50 ppm of benzaldehyde; at most 50 ppm of 2-furaldehyde; and at least 20 mol % of at least one alkali metal cation. A process for preparing this solution and the use of this solution for preparation of a polymer by free-radical polymerization. | 2013-01-03 |
20130005926 | PROCESS FOR PRODUCING WATER-ABSORBING RESIN - The disclosed process for producing a water-absorbing resin comprising: a polymerization step of polymerizing an aqueous unsaturated monomer; and a drying step of drying a particulated water-containing gel-liked crosslinked polymer, obtained in a finely crushing step during the polymerization or after the polymerization. In the process, the drying step is interrupted with a dryer kept in a heated state and thereafter the drying step is restarted. | 2013-01-03 |
20130005927 | METHOD OF FORMING THERMOPLASTIC ARTICLE - A method of forming a thermoplastic article, comprises steps of a) positioning at least one preheated first component being hollow and having at least one open end in two co-operating first mould halves; b) extruding a blow-mouldable thermoplastic material into the first component and closing the mould halves; and c) blowing the blow-moldable thermoplastic material inside the mould halves to form an article on which the first component is fixedly engaged. The method is simple in implementation, low in cost and easy in modification, and by which a thermoplastic article of varied colors, patterns, materials, and/or functional components being fixedly mounted on its outer surface could be realized. | 2013-01-03 |
20130005928 | OPTICAL DOUBLE-SIDED PRESSURE-SENSITIVE ADHESIVE SHEET, OPTICAL MEMBER, TOUCH PANEL, IMAGE DISPLAY DEVICE, AND SEPARATING METHOD - The present invention provides an optical double-sided pressure-sensitive adhesive sheet excellent in reworkability, step absorbability and anti-foaming release property. The invention relates to an optical double-sided pressure-sensitive adhesive sheet including an acrylic pressure-sensitive adhesive layer which contains an acrylic polymer (X), wherein: the acrylic polymer (X) is formed from a monomer component including an alkyl(meth)acrylate having a linear or branched alkyl group having 1 to 14 carbon atoms in an amount of 50 to 100 wt % based on a total amount of the monomer component (100 wt %) forming the acrylic polymer (X), and a content of a polar group-containing monomer is 0 to 15.0 wt % based on the total amount thereof; and a gel fraction of the acrylic pressure-sensitive adhesive layer is from 20 to 74 wt %. | 2013-01-03 |
20130005929 | FLASHLINE HEATER SYSTEM AND METHOD - The present embodiments provide a system and method for separation within a polymer production process. Specifically, a flashline heater configured according to present embodiments may provide more time than is required for complete vaporization of liquid hydrocarbons that are not entrained within a polymer fluff produced within a polymerization reactor. Such extra time may allow for liquid hydrocarbons that are entrained within the polymer fluff to be vaporized. | 2013-01-03 |
20130005930 | ETHYLENE-alpha-OLEFIN COPOLYMER AND MOLDED ARTICLE - An ethylene-α-olefin copolymer, wherein the ethylene-α-olefin copolymer has a density of 860 to 950 kg/m | 2013-01-03 |
20130005931 | ETHYLENIC POLYMER - Disclosed is an ethylenic polymer having a long characteristic relaxation time. The ethylenic polymer satisfies the following requirements:
| 2013-01-03 |
20130005932 | FLUORENE COPOLYMER, METHOD FOR PREPARATION AND USE THEREOF - A fluorene copolymer, method for preparation thereof, and use thereof are provided. Said fluorene copolymer comprises copolymer represented by formula (I), wherein R | 2013-01-03 |
20130005933 | COPOLYMER COMPRISING ANTHRACENE AND BENZOSELENADIAZOLE, PREPARING METHOD AND USES THEREOF - A copolymer comprising anthracene and benzoselenadiazole, preparing method and uses thereof are disclosed. The copolymer is represented by formula (I), wherein n is a natural number from 10 to 1000, a is 1 or 2, b is 0, 1 or 2, X, Y are O, S, Se, SO | 2013-01-03 |
20130005934 | Polymerizable Composition, and Resin and Optical Part Using the Same - A polymerizable composition including a compound represented by following General Formula (1): | 2013-01-03 |
20130005935 | Preparing Organopolysiloxanes - Organopolysiloxane resins are prepared by reacting tetrachlorosilane with a mixture of 1.0 to 7.0 mol of monohydric alcohol per mol of tetrachlorosilane and 0 to 2 mol of water per mol of tetrachlorosilane to form a partial alkoxylate, followed by the mixing the partial alkoxylate with a water-insoluble organic solvent having a density below 0.95 kg/l and a monofunctional silane of the formula R | 2013-01-03 |
20130005936 | NOVEL CASTOR OIL DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF - Novel compounds of formula (1) wherein: A is especially a linear or branched divalent alkylene radical having between 1 and 10 carbon atoms, and Y is especially a hydrogen atom. | 2013-01-03 |
20130005937 | NOVEL METHOD FOR PREPARING POLYOLS AND PRODUCTS OBTAINED - The present invention relates to a method for preparing polyols of formula (I″) | 2013-01-03 |
20130005938 | PHOSPHORUS-CONTAINING COMPOUNDS AND THEIR PREPARATION PROCESS AND USE - A series of novel phosphorus-containing compounds having the following formula is provided: | 2013-01-03 |
20130005939 | OPTICAL FILM - An optical film comprising a copolycarbonate composed of 25 to 90 mol % of unit (A) of the following formula, | 2013-01-03 |
20130005940 | POLYIMIDE NANOWEB - A nanoweb that contains a plurality of nanofibers wherein the nanofibers contain a fully aromatic polyimide that is characterized by having a crystallinity index (CI) and a degree of imidization (DOI). The product of the DOI and the CI is between 0.08 and 0.25 or above a lower limit to obtain a desired tensile strength and/or toughness. The nanoweb may for example have a tensile strength per unit basis weight of greater than 15 kg/cm | 2013-01-03 |
20130005941 | ELECTROCHROMIC MATERIAL AND A METHOD FOR PRODUCING THE SAME - Disclosed are an electrochromic material containing a π-electron based conjugated polymer that changes from a desired color developed state to a decolored state and a method for producing the same. The electrochromic material contains a π-electron based conjugated polymer as shown in chemical formula (1). | 2013-01-03 |
20130005942 | METHODS OF PRODUCING POLYANTHRACENE AND USES THEREOF - The present application provides methods of producing polyanthracene including polymerization of anthracene monomers in the presence of oxidants and reaction solvents. The present application further provides polyanthracene produced by methods described herein that has higher solubility in organic solvents and better thermal stability and ablation resistance. | 2013-01-03 |
20130005943 | Methods for Preparing Internally Constrained Peptides and Peptidomimetics - The present invention relates to a method for preparing a peptide having a stable, internally constrained alpha-helical, beta-sheet/beta-turn, 3 | 2013-01-03 |
20130005944 | CXCR4 Receptor Compounds - The invention relates generally to compounds which are allosteric modulators {e.g., positive and negative allosteric modulators, and allosteric agonists) of the G protein coupled receptor for stromal derived factor 1 (SDF-I), also known as the CXCR4 receptor. The CXCR4 receptor compounds are derived from the intracellular loops and domains of the CXCR4 receptor. The invention also relates to the use of these CXCR4 receptor compounds and pharmaceutical compositions comprising the CXCR4 receptor compounds in the treatment of diseases and conditions associated with CXCR4 modulation such as bone marrow transplantation, chemosensitization, cancer, metastatic disease (e.g., cancer), auto-immune disease (e.g., rheumatoid arthritis), fibrosis disease (e.g., pulmonary), AIDS infection, cardiovascular disease, uveitis, inflammatory diseases, celiac disease HIV infection and stem cell-based regenerative medicine. | 2013-01-03 |
20130005945 | FORMING POROUS SCAFFOLD FROM CELLULOSE DERIVATIVES - Scaffold comprises a polymer defining macropores and comprising hydroxypropylcellulose partially substituted by a substituent comprising a self-crosslinkable group, which is crosslinked through the self-crosslinkable group. The macropores have an average pore size larger than 50 microns and are at least partially interconnected. In one method, bicontinuous emulsion comprising a continuous aqueous phase and a continuous polymer phase is formed. The polymer phase comprises hydroxypropylcellulose partially substituted by a substituent comprising a self-crosslinkable group, and is crosslinked through the self-crosslinkable group to form a polymer defining at least partially interconnected pores. In another method, phase separation is induced in a solution comprising a polymer precursor and water to form a bicontinuous emulsion comprising a continuous polymer phase and a continuous aqueous phase. The polymer precursor comprises a self-crosslinkable group and is crosslinked through the self-crosslinkable group in the emulsion to form a polymer defining at least partially interconnected macropores. | 2013-01-03 |
20130005946 | CANOLA PROTEIN PRODUCT WITH LOW PHYTIC ACID CONTENT ("C702") - Canola protein products having a protein content of at least about 60 wt % (N×6.25) d.b., preferably at least about 90 wt %, more preferably at lease about 100 wt %, and low phytic acid content, are produced by extracting canola seeds or canola oil seed meal with an aqueous calcium salt solution, preferably calcium chloride solution, to cause solubilization of canola protein from the seeds or meal. | 2013-01-03 |
20130005947 | METHOD FOR REMOVING A LYTIC ENZYME FROM A HETEROGENEOUS MIXTURE - The invention relates to purification of an intact, non-degraded macromolecule from a biological mixture comprising the macromolecule in the presence of its lytic enzyme. The method comprises providing the biological mixture as a heterogeneous mixture comprising the lytic enzyme, at least partially, in soluble form and the macromolecule, at least partially, in non-soluble form; batch-wise contacting the heterogeneous mixture with an immobilized inhibitor of the lytic enzyme; increasing the solubility of the macromolecule in the mixture; and removing the immobilized inhibitor from the mixture. | 2013-01-03 |
20130005948 | METHOD FOR PURIFYING POLYPEPTIDE SOLUTIONS - Herein is reported a method for purifying cell cultivation supernatants either directly after fermentation or after one or more preliminary purification steps, such as protein A affinity chromatography. By adjusting the pH value in the acid range and subsequent incubation of the acidified solution host cell nucleic acid and host cell protein can be precipitated but the target polypeptide remains in solution. Thereafter the precipitate and therewith the contaminating host cell components can be removed by a simple physical separation step. | 2013-01-03 |
20130005949 | ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF - The present invention relates to antibodies against human CSF-1R (CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. | 2013-01-03 |
20130005950 | Stirred Tank Reactor And Method - Container for sample preparation or processing, such as biomass culturing or processing, and optionally sample purification. In certain embodiments, the reactor is a bioreactor that includes a stirred cell device that simulates a tangential flow filter to reduce or eliminate clogging that can be caused by the solids generated. In certain embodiments, the solids comprise a precipitate or floc or beads, such as one that includes a polymer that binds the biomolecule(s) of interest, and impurities. In its method aspects, embodiments disclosed herein include purification and isolation of biomolecules of interest derived from cell culture fluids. The methods include carrying out sample preparation or processing in a container, culturing a biomass; generating solids by precipitating or flocculating a biomolecule of interest from the cultured broth; preventing the solids from settling in the container by agitation; and purification, such as by eluting the biomolecule of interest and filtering the same. | 2013-01-03 |
20130005951 | PROCESS FOR PREPARING FGF21 WITH LOW DEGREE OF O-GLYCOSYLATION - Expression of FGF21 in a | 2013-01-03 |
20130005952 | RECOVERY OF LIGNIN AND WATER SOLUBLE SUGARS FROM PLANT MATERIALS - In one aspect, a process for treating woody plant material is provided, the process involving contacting the plant material with a continuous flow of an aqueous ethanol solution at elevated temperature and pressure under conditions that promote extraction of ethanol-soluble lignin from the plant material and retention of hemicellulose sugars, xylose and cellulose in the treated plant material solids. In another aspect, a process for extracting hemicellulose sugars from lignin-depleted plant material solids is provided, the process involving contacting lignin-depleted plant material with water at elevated temperature and pressure under conditions that promote extraction of hemicellulose sugars from the plant material; and recovering hemicellulose sugars from the liquid mixture. | 2013-01-03 |
20130005953 | Readthrough Inducing Agent and Drug for Treating Genetic Disease Caused by Nonsense Mutation - A readthrough inducing agent for inducing readthrough of a premature stop codon generated by nonsense mutations, the readthrough inducing agent comprising a compound having a structure expressed by the following Structural Formula (A), and a drug for treating a genetic disease caused by nonsense mutations, the drug comprising the readthrough inducing agent. | 2013-01-03 |
20130005954 | PROCESS FOR PREPARING HEPARINOIDS AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF - Processes are disclosed for the synthesis of the Factor Xa anticoagulant fondaparinux and related compounds. Protected pentasaccharide intermediates and efficient and scalable processes for the industrial scale production of fondaparinux sodium by conversion of the protected pentasaccharide intermediates via a sequence of deprotection and sulfonation reactions are provided. | 2013-01-03 |
20130005955 | Micro Rotary Machine and Methods for Using Same - A micro rotary machine may include a micro actuator and a micro shaft coupled to the micro actuator. The micro shaft comprises a horizontal shaft and is operable to be rotated by the micro actuator. A micro tool is coupled to the micro shaft and is operable to perform work in response to motion of the micro shaft. | 2013-01-03 |
20130005956 | Synthesis of 18F-labeled Tracers in Hydrous Organic Solvents - A method for synthesizing an | 2013-01-03 |
20130005957 | METHOD FOR PRODUCING CATIONIZED CELLULOSE AND METHOD FOR PRODUCING CATIONIZED HYDROXYALKYL CELLULOSE - A production method of a cationized cellulose or a cationized hydroxyalkylcellulose, including step 1 for adding a cationizing agent to cellulose and mechanically decrystallizing the cellulose and step 2 for adding a basic compound to the mixture obtained in step 1 and mechanically decrystallizing the cellulose, or a production method of a cationized cellulose or a cationized hydroxyalkylcellulose, including a step 3 for adding a basic compound to cellulose and mechanically decrystallizing the cellulose and step 4 for adding a cationizing agent to the mixture obtained in step 3 and mechanically decrystallizing the cellulose. The cellulose and the cationizing agent are allowed to react with each other in step 2 or step 4. | 2013-01-03 |
20130005958 | DEVICES AND METHODS FOR REDUCING RADIOLYSIS OF RADIOISOTOPES - Disclosed are devices and methods for reducing radiolysis of radiopharmaceuticals during filtration, concentration and purification. The devices comprises two or more confining geometry having a cross-section dimension below the beta(+) or beta(−) range of the radioisotope in use, when containing the radioisotope, and configured in such a way that neighboring geometries are isolated from its nearest neighbor such that no measurable kinetic positron energy transfer occurs between the confining geometries when containing the radioisotope. Methods of filtration of radioisotope containing mixtures are also disclosed. | 2013-01-03 |
20130005959 | ANTI-ALLERGIC AGENT - According to the present invention, an anti-allergic agent is provided which includes a polysaccharide comprising galactose, glucose and rhamnose as constituents, or includes a microorganism belonging to a genus | 2013-01-03 |
20130005960 | METHOD FOR PRODUCING AMIDE COMPOUND - The present invention relates to a method for producing a high purity, high quality amide compound, particularly, lactam. A first embodiment of the present invention is characterized in that an amount of each of a halide, an aldehyde compound, an alcohol compound and a nitrile compound contained in a solution recycled into an oxime-forming step is controlled to an amount of 0.4 mol % or less based on the ketone as a starting material. A second embodiment of the present invention is characterized in that one or more compounds selected from the group consisting of a ketone, an oxime and an amide compound are purified by hydrogenation and/or crystallization for eliminating impurities containing a double bond. A third embodiment of the present invention is characterized in that a content of impurities having a cyclic bridge structure is controlled by using a cycloalkanone purified by recrystallization. | 2013-01-03 |
20130005961 | NOVEL COMPOUND AND PROCESS FOR PRODUCING AMIDE COMPOUND THEREWITH - The present invention provides novel cyclododecanone-O-azacyclotridecen-2-yloxime and cyclododecanone-O-azacyclotridecen-2-yloxime hydrochloride. The invention also provides a process for producing an amide compound wherein cyclododecanone-O-azacyclotridecen-2-yloxime, hydrogen chloride and/or Lewis acid or cyclododecanone-O-azacyclotridecen-2-yloxime hydrochloride are used as a rearrangement catalyst and/or a reaction starting material in a reaction step. | 2013-01-03 |
20130005962 | PROCESS FOR THE SYNTHESIS OF DERIVATIVES OF 3-AMINO-TETRAHYDROFURAN-3-CARBOXYLIC ACID AND USE THEREOF AS MEDICAMENTS - The present invention relates to a process for the manufacturing of substituted 3-amino-tetrahydrofuran-3-carboxylic acid amides of general formula (I) and their precursors in high optical purity to the precursors of the synthesis of substituted S-Amino-tetrahydrofuran-5-carboxylic acid amides of general formula (I) in high optical purity, and to the tautomers, enantiomers, diastereomers, mixtures and salts of substituted 3-amino-tetrahydrofuran-3-carboxylic acid amides of general formula (I) in high optical purity, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable properties. | 2013-01-03 |
20130005963 | ORGANIC PHOTOELECTRIC CONVERSION MATERIAL AND ORGANIC THIN-FILM PHOTOELECTRIC CONVERSION DEVICE - An organic photoelectric conversion material for use in an organic thin-film photoelectric conversion device, containing a compound represented by formula 1; and an organic thin-film photoelectric conversion device having a photoelectric conversion layer which containing the organic photoelectric conversion material: | 2013-01-03 |
20130005964 | SULFONYL AMIDE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELL GROWTH - The present invention relates to a compound of the formula I | 2013-01-03 |
20130005965 | ARYL- AND HETEROARYL-SUBSTITUTED TETRAHYDROISOQUINOLINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE, AND SEROTONIN - The compounds of the present invention are represented by the chemical structure found in Formula (I): | 2013-01-03 |
20130005966 | PROCESS FOR THE PREPARATION OF IMIDAZO[2,1-B][1,3]BENZOTHIAZOLE DERIVATIVES - Provided herein are process for the preparation of N-(5-ferf-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-fe][1,3]benzothiazol-2-yl]phenyl}urea, or a pharmaceutically acceptable salt, solvate, hydrate, or polymorph thereof. N-(5-tert-Butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-&][1,3]benzo-thiazol-2-yl]phenyl}urea is useful for treating, preventing, and/or managing diseases or conditions, including but not limited to, proliferative diseases, FLT-3 mediated diseases, and cancers. N-(5-ferf-Butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-&][1,3]benzothiazol-2-yl]phenyl}urea is represented by the structure: | 2013-01-03 |
20130005967 | METHOD FOR PREPARING (R)-3-(3-FLUORO-4-(1-METHYL-5,6-DIHYDRO-1,2,4-TRIAZIN-4(1H)-YL)PHENYL)-5-- (SUBSTITUTED METHYL)OXAZOLIDIN-2-ONE DERIVATIVES - Provided are a method for preparing (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives, which are oxazolidinone antibiotic compounds having a cyclic amidrazone group, represented by Chemical Formula 1, and intermediates thereof, and uses 3,4-difluoro-4-nitrobenzen as a starting material. According to the preparation method of the present invention, (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives, which are useful as oxazolidinone antibiotics, can be prepared in high purity and high yield in a simpler manner than conventional methods. | 2013-01-03 |
20130005968 | SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS - The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib. | 2013-01-03 |
20130005969 | PROCESS FOR THE PREPARATION OF TENOFOVIR DISOPROXIL FUMARATE - The present invention relates to an improved process for the preparation of Tenofovir Disoproxil and its pharmaceutically acceptable salts comprising the steps of: a) esterifying Tenofovir with chloromethyl isopropyl carbonate in presence of a base, phase transfer catalyst and optionally dehydrating agent, in a suitable solvent; b) optionally purifying Tenofovir Disoproxil; and c) converting of Tenofovir Disoproxil into its pharmaceutically acceptable salts. The present invention further relates to a process for the preparation of Tenofovir by reacting 1-(6-amino-purin-9-yl)-propan-2-ol with toluene-4-sulfonic acid diethoxy phosphoryl methyl ester in presence of a base in a non-polar solvent medium followed by hydrolysis. | 2013-01-03 |
20130005970 | Method for the production of beta-ketonitriles - The present invention relates to a process for preparing β-ketonitriles of the general formula I | 2013-01-03 |
20130005971 | Process and Intermediates for Preparing Lapatinib - The present invention provides a process for making lapatinib and its pharmaceutically acceptable salt by use of new intermediates. A new process for obtaining a pharmaceutical form of lapatinib ditosylate monohydrate is also provided. | 2013-01-03 |
20130005972 | Application of Staudinger Ligation in PET Imaging - A method for generating a radiolabeled tracer. The method includes providing a phosphine molecule having at least one carbocyclic, aromatic, or pyrrolidinyl ring with an OH substitute. The OH of this phosphines molecule is then condensed with an acid to produce a phosphine ester. Staudinger ligation is then performed to generate the radiolabeled tracer by treating the phosphine ester with a radiolabeled azide having a PET radioisotope moiety. | 2013-01-03 |
20130005973 | PROCESS FOR PREPARING VORICONAZOLE BY USING NEW INTERMEDIATES - Provided is a process for preparing Voriconazole represented by Chemical Formula 1. More particularly, the process for preparing Voriconazole of Chemical Formula 1 includes: carrying out the Reformatsky-type coupling reaction between a ketone derivative of Chemical Formula 4 and a pyrimidine derivative of Chemical Formula 5 to obtain a compound of Chemical Formula 3; reacting the substituents halo and oxysulfonyl with a hydrogen donor to obtain racemic Voriconazole of Chemical Formula 2; and carrying out optical isolation of the racemic Voriconazole by adding an adequate optically active acid thereto to obtain Voriconazole having high optical purity with high cost-efficiency and high yield. | 2013-01-03 |
20130005974 | SYNTHESIS OF A NEUROSTIMULATIVE PIPERAZINE - The invention describes an improved synthesis for piperazine derivatized with nicotinic acid and a benzyl moiety. The product compounds are useful for treatment of neurological conditions. | 2013-01-03 |
20130005975 | EMISSIVE TRANSITION-METAL COMPLEXES WITH BOTH CARBON-PHOSPHORUS ANCILLARY AND CHROMOPHORIC CHELATES, SYNTHETIC METHOD OF PREPARING THE SAME AND PHOSPHORESCENT ORGANIC LIGHT EMITTING DIODE THEREOF - The present invention provides a phosphorescent tris-chelated transition metal complex having one carbon-nitrogen (ĈN) or nitrogen-nitrogen (N̂N) chromophoric ligand forming a coordination sphere thereof with a transition metal, and two identical carbon-phosphorus (ĈP) chelates being incorporated into the coordination sphere, wherein the metal is iridium, platinum, osmium or ruthenium, and the chromophoric ligands possess a relatively lower energy gap in comparison with that of the non-chromophoric chelate, the latter afforded an effective barrier for inhibiting the ligand-to-ligand charge transfer process, so that bright phosphorescence can be observed. The architecture and energy gap of the present molecular designs are suitable for generation of high efficiency blue, green and even red emissions. | 2013-01-03 |
20130005976 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV - A process for preparing [(1R,2R)-4-oxo-1,2-cyclopentanedicarboxylic acid II, by the resolution of racemic 4-oxo-1,2-cyclopentanedicarboxylic acid (V), said process comprising:
| 2013-01-03 |
20130005977 | Oxycodone Hydrochloride Having Less Than 25 PPM 14-Hydroxycodeinone - In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone. | 2013-01-03 |
20130005978 | PROCESS FOR THE MANUFACTURE OF PHARMACEUTICALLY ACTIVE COMPOUNDS - The present invention further relates to a process for the manufacture of compound (I), | 2013-01-03 |
20130005979 | THIENOPYRIDINE DERIVATIVE, METHOD FOR PRODUCING SAME AND ORGANIC SEMICONDUCTOR DEVICE USING SAME - This invention relates to a novel thienopyridine derivative represented by formula (1), which is useful as an organic semiconductor device, such as an organic thin film transistor element, and the invention also relates to method for producing the thienopyridine derivative represented by formula (1): | 2013-01-03 |
20130005980 | PROCESS FOR THE PREPARATION OF SORAFENIB TOSYLATE - The present invention provides a process for the preparation of sorafenib tosylate, comprising contacting sorafenib free base with p-toluenesulphonic acid in water. | 2013-01-03 |
20130005981 | PROCESS FOR PREPARATION OF t-BUTOXYCARBONYLAMINE COMPOUNDS - Provided is a process for the preparation of t-butoxycarbonylamine compounds, which comprises using phosgene or a phosgene equivalent, t-butanol, and an organic base. Even when applied to a primary or secondary amine compound having low nucleophilicity, the process enables highly selective preparation of a t-butoxycarbonylamine compound at a low cost. In the process, a t-butoxycarbonylamine compound is prepared using: phosgene or a phosgene equivalent; t-butanol; an organic base; and either a primary or secondary amine compound or a primary or secondary ammonium salt. | 2013-01-03 |
20130005982 | NOVEL DIARYL SULFONE COMPOUND, AND MANUFACTURING METHOD FOR SAME - The present invention provides a diaryl sulfone compound represented by Formula (1): | 2013-01-03 |
20130005983 | METHOD FOR PRODUCING 3-HALO-1,2-BENZISOTHIAZOLES - A method for producing a 3-halo-1,2-benzisothiazole represented by the general formula (2): | 2013-01-03 |
20130005984 | 11C-LABELED BENZOPHENONE/BENZOXAZOLE ANALOGUES AS AN INFLAMMATION IMAGING AGENT - A method of preparing novel [ | 2013-01-03 |
20130005985 | Process Using Grignard Reagents - The present invention relates to a process using Grignard reagents for providing thio-triazolo group-containing compounds. | 2013-01-03 |
20130005986 | N-Carbomethoxy-N-methoxy-(2-chloromethyl)-anilines, their preparation and their use as precursors for preparing 2-(pyrazol-3'-yloxymethylene)-anilides - The present invention relates to N-carbomethoxy-N-methoxy-(2-chloromethyl)-aniline compounds of the formula I, wherein: n is 0, 1, 2 or 3, each R | 2013-01-03 |
20130005987 | CRYSTALLINE FORMS OF THE MONO-SODIUM SALT OF D-ISOGLUTAMYL-D-TRYPTOPHAN - The present invention relates to crystalline forms of the mono-sodium salt of D-isoglutamyl-D-tryptophan, pharmaceutical compositions comprising them, their use in the treatment of various diseases and conditions, and processes for their preparation. In particular, the present invention relates the crystal modification 1 (polymorphic form F) of the mono-sodium salt of D-isoglutamyl-D-tryptophan. | 2013-01-03 |
20130005988 | 2-AZETIDINEMETHANEAMINES AND 2-PYRROLIDINEMETHANEAMINES AS TAAR-LIGANDS - The present invention relates to compounds of formula I | 2013-01-03 |
20130005989 | HETEROCYCLIC QUINOID THIOPHENE ORGANIC PHOTOELECTRIC MATERIAL, PREPARATION METHOD AND APPLICATION THEREOF - A heterocyclic quinoid thiophene organic photoelectric material, which comprises a compound represented by formula (1), in which R | 2013-01-03 |
20130005990 | METHOD FOR PRODUCING ACRYLATE DERIVATIVE, ACRYLATE DERIVATIVE, AND INTERMEDIATE THEREOF - Provided are 1) a production process for an acrylic ester derivative capable of being a raw material of a polymer for obtaining a photoresist composition capable of forming a photoresist film which is excellent in a reactivity to acid and a heat stability and is less swollen in developing and which has a refractive index of preferably 1.72 or more in 193 nm and can be patterned, 2) an acrylic ester derivative obtained by the above production process and 3) alcohol and ester which are synthetic intermediates for the above acrylic ester derivative. | 2013-01-03 |
20130005991 | INTERMEDIATES OF 1-O-ACYL-2-DEOXY-2-FLUORO-4-THIO-BETA-D-ARABINOFURANOSES - The present invention relates to a process for preparing 1-O-acyl-2-deoxy-2-fluoro-4-thio-β-D-arabinofuranoses having formula I and intermediates thereof: | 2013-01-03 |
20130005992 | METHOD FOR PRODUCING OPTICALLY ACTIVE N-MONOALKYL-3-HYDROXY-3-ARYLPROPYLAMINE COMPOUND - The present invention provides a method for producing an N-monoalkyl-3-hydroxy-3-arylpropylamine compound represented by Formula (2): | 2013-01-03 |
20130005993 | NOVEL DIARYL SULFONE COMPOUND, AND MANUFACTURING METHOD FOR SAME - The present invention provides a diaryl sulfone compound represented by Formula (1) below: | 2013-01-03 |
20130005994 | PROCESS FOR THE PREPARATION OF CYCLIC ENOL ETHERS - The present invention relates to a process for the preparation of cyclic enol ethers. | 2013-01-03 |
20130005995 | METHOD FOR PREPARING A FATTY ACID DERIVATIVE - A method for manufacturing a fatty acid derivative represented by formula (I) is provided: | 2013-01-03 |
20130005996 | METHOD FOR PREPARING A FATTY ACID DERIVATIVE - A method for manufacturing a fatty acid derivative represented by formula (I) is provided: | 2013-01-03 |
20130005997 | PREPARATION OF 2,2-BIS (FLUOROALKYL) OXIRANE AND PREPARATION OF PHOTOACID GENERATOR THEREFROM - A 2,2-bis(fluoroalkyl)oxirane (A) is prepared by reacting a fluorinated alcohol (1) with a chlorinating, brominating or sulfonylating agent under basic conditions to form an oxirane precursor (2) and subjecting the oxirane precursor to ring closure under basic conditions. R | 2013-01-03 |
20130005998 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES - A process for preparing a divinylarene dioxide including reacting (a) at least one divinylarene; (b) at least one oxidant, wherein the at least one oxidant is a partially neutralized sulfuromonoperoxoic acid such as partially neutralized Caro's acid solution; (c) at least one basic compound; (d) optionally, at least one solvent, and (e) optionally, at least one catalyst; wherein the process is carried out under conditions to form a divinylarene dioxide product. | 2013-01-03 |
20130005999 | METHOD FOR REGENERATING TITANOSILICATE CATALYSTS - A method for regenerating a titanosilicate catalyst, comprising a step of mixing a titanosilicate having reduced catalytic ability with a cyclic secondary amine, and a method for producing an oxirane compound, which comprises a step of reacting hydrogen peroxide with a C2-C12 compound having a carbon-carbon double bond, in the presence of a titanosilicate catalyst obtained by the regeneration method. | 2013-01-03 |
20130006000 | PROCESS FOR PREPARING DIVINYLARENE DIOXIDES - A process for preparing a divinylarene dioxide including reacting (a) at least one divinylarene; and (b) at least one peracid oxidant compound, under conditions to form a divinylarene dioxide product; wherein the peracid oxidant compound is capable of providing an increased yield of a divinylarene dioxide product. | 2013-01-03 |
20130006001 | MANUFACTURE OF AN EPOXYETHYL CARBOXYLATE OR GLYCIDYL CARBOXYLATE - The invention relates to a process for the manufacture of an epoxyethyl carboxylate or glycidyl carboxylate, including reacting a vinyl carboxylate or an allyl carboxylate using an oxidant and a water-soluble manganese complex in an aqueous reaction medium, and the water-soluble manganese complex comprises an oxidation catalyst, characterized in that the water-soluble manganese complex is a mononuclear species of the general formula (I) [LMnX | 2013-01-03 |
20130006002 | PROCESS FOR PREPARATION OF A CATALYST CARRIER - This invention relates to catalyst carriers to be used as supports for metal and metal oxide catalyst components of use in a variety of chemical reactions. More specifically, the invention provides a process of formulating a low surface area alpha alumina carrier that is suitable as a support for silver and the use of such catalyst in chemical reactions, especially the epoxidation of ethylene to ethylene oxide. A precursor for a catalyst support comprises an admixture of an alpha alumina and/or a transition alumina; a binder; and either a solid blowing agent which expands, or propels a gas upon the application of sufficient heat, and optionally contains talc and/or water soluble titanium compound. | 2013-01-03 |
20130006003 | NEW SYNTHONES FOR PREPARATION OF 19-NOR VITAMIN D DERIVATIVES - The present invention discloses the synthone of Formula (I), wherein R | 2013-01-03 |
20130006004 | DELTA-15 DESATURASE GENES SUITABLE FOR INCREASING LEVELS OF OMEGA-3 FATTY ACIDS - The present invention relates to fungal Δ-15 fatty acid desaturases that are able to catalyze the conversion of linoleic acid (18:2, LA) to alpha-linolenic acid (18:3, ALA). Nucleic acid sequences encoding the desaturases, nucleic acid sequences which hybridize thereto, DNA constructs comprising the desaturase genes, and recombinant host plants and microorganisms expressing increased levels of the desaturases are described. Methods of increasing production of specific omega-3 and omega-6 fatty acids by over-expression of the Δ-15 fatty acid desaturases are also described herein. | 2013-01-03 |
20130006005 | PROCESS FOR PREPARING LINEAR ALPHA,OMEGA-DICARBOXYLIC DIESTERS - The invention provides a process for preparing linear alpha,omega-dicarboxylic diesters by reacting a triglyceride containing fatty acid residues having monounsaturated or polyunsaturated carbon chains with carbon monoxide, an acid and an OH-group donor in one reaction step in the presence of a catalyst. | 2013-01-03 |
20130006006 | Chemicals Produced from Oil-Bearing Microbial Biomass - Chemicals prepared from oleaginous microbes and related methods are provided. | 2013-01-03 |
20130006007 | ACTIVATABLE NANOPROBES FOR INTRACELLULAR DRUG DELIVERY - An activatable nanoprobe is provided having a core component and an active agent associated with the core component via a bond configured to be cleaved upon exposure to an endogenous compound. | 2013-01-03 |
20130006008 | PROCESS FOR PREPARATION OF (Z)-CYANOALKENYLCYCLOPROPANECARBOXYLIC ACID COMPOUNDS - A method for producing a (Z)-cyanoalkenyl-cyclopropanecarboxylic acid compound, which includes the step of isomerizing an (E)-cyanoalkenyl-cyclopropanecarboxylic acid compound (1) into a (Z)-cyanoalkenyl-cyclopropanecarboxylic acid compound (2) in the presence of at least one isomerizing catalyst selected from the group consisting of bromine, hydrogen bromide, brominated carboxylic acids, brominated phosphorus compounds, N-brominated imide compounds, N-brominated amide compounds, brominated alkylsilane compounds, thionyl bromide, brominated boron compounds, brominated aluminum compounds, thiol compounds, disulfide compounds, thiocarboxylic acid compounds, nitric acid and nitrate salts: | 2013-01-03 |
20130006009 | PROCESS FOR CONTINUOUSLY PRODUCING GEOMETRIC SHAPED CATALYST BODIES K - A process for producing geometric shaped catalyst bodies K whose active material is a multielement oxide which comprises the element Mo, the elements Bi and/or V and one or more of the elements Co, Ni, Fe, Cu and alkali metals, in which sources of the different elements are used to obtain a finely divided mixture which is coarsened to a powder by press agglomeration, the coarsened powder is used to form, by press agglomeration, shaped bodies V which are separated into undamaged shaped bodies V | 2013-01-03 |