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01st week of 2009 patent applcation highlights part 53
Patent application numberTitlePublished
20090005201Pulley assembly for a power transmission belt - A pulley assembly has a first body to engage a power transmission belt. The first body is rotatable around a first axis. A second body is movable relative to the first body around the first axis. First and second axially spaced elastic members each has a radially inner portion and a radially outer portion. One of: (a) the radially inner portions of the first and second members; and (b) the radially outer portions of the first and second members are: (i) coupled to move together around the first axis; and (ii) each movable relative to the first and second bodies around the first axis. The other of: (a) the radially inner portions of the first and second members; and (b) the radially outer portions of the first and second members are fixedly coupled, one each to the first and second bodies, to follow movement of the first and second bodies around the first axis.2009-01-01
20090005202BELT TENSIONER AND METHOD FOR MAKING A BELT-TENSIONER ARM AND A SPRING CASE - A belt tensioner includes an arm, a spring case, and a helical spring having inwardly projecting first and second end portions. Another belt tensioner includes a spring, an arm, a spring case, and a pivot bushing surrounding the spring. An additional belt tensioner includes an idler pulley having a bearing with a mounting hole and includes an arm having a post. The post is positioned in the mounting hole, and an annular rim of the post is deformed radially outward and over the bearing. A method for manufacturing an arm and a spring case of a belt-tensioner includes obtaining a belt-tensioner-arm casting mold including a first section and a second section and obtaining a belt-tensioner-spring-case casting mold including a first segment and a second segment.2009-01-01
20090005203Belt tensioner for coupon insertion apparatus - A coupon insertion apparatus configured for sequentially inserting coupons into receiving containers, including a machine frame, at least one pair of opposed rollers mounted to the frame and adjustable between a closed position and an open position. A drive system includes a drive belt for simultaneously driving the opposed rollers in both of the positions. A tensioner is connected to the belt and is movable generally transversely to a direction of the adjustment of the drive rollers to maintain a designated tension on the drive belt.2009-01-01
20090005204MECHANICAL SPEED REDUCER BY BELT - The present invention refers to a mechanism for mechanical speed reducer or overdrive in which for each reducing stage there are two pulleys or sprockets disposed laterally and in parallel position between themselves, moreover one of them in orbital motion provided by a eccentric cam reciprocal to the reducer input element and the other pulley or sprocket disposed at the same input element center and the torque transmission between the pulleys or sprockets is done through a belt.2009-01-01
20090005205Power transmission device - A power transmission device is provided to transmit power from an engine to a transmission, including a transmission mechanism, a first clutch, a second clutch, a damper mechanism, and a casing. The transmission mechanism is configured to transmit power with two kinds of rotational speeds that vary in stages. The first clutch is configured to switch rotational speed in the transmission mechanism to decrease the speed ratio. The second clutch is configured to set the rotational speed ratio of the transmission mechanism so that output rotational speed equals input rotational speed, that is, the transmission mechanism is in a fixed state.2009-01-01
20090005206HYDRAULIC FEED SYSTEM FOR A TRANSMISSION - The present invention provides an assembly for use in a transmission that includes a first rotating member having a first portion and a second portion, the second portion having an outer diameter greater than an outer diameter of the first portion and having a bore with an open end. An annulus has a port for providing a fluid and is disposed proximate to the first portion. A second rotating member is at least partially located within the bore and extends from the open end. A first passage is connected to the port of the annulus and a second passage is connected to the first passage. The second passage is located through the second portion. A third passage is connected to the second passage and is located in the second rotating member. Fluid is able to flow from the port through the passages to provide fluid to the second rotating member.2009-01-01
20090005207Gear stage of an actuating drive - In the case of a gear stage (2009-01-01
20090005208Eight Speed Transmission with Planetary and Layshaft Gearing - A transmission is provided that utilizes three planetary gear sets and three layshaft gear sets, as well as four rotating-type clutches and one brake that are engagable in different combinations to provide eight forward speed ratios between an input member and an output member of the transmission. By combining features of a layshaft transmission with those of a planetary transmission, the low spin losses and packaging convenience typical of a layshaft transmission are available while still achieving the high torque capacity typical of a planetary transmission.2009-01-01
20090005209Multi-Speed Transmission - A multi-speed transmission offers seven forward speed ratios with a pleasing ratio step progression, with the seventh forward speed ratio offering a relatively large percentage of the ratio spread, relatively low pinion speeds and only light torque loading on gear members carrying torque in the seventh forward speed ratio due to a brake-type torque transmitting mechanism engaged in the seventh forward speed ratio.2009-01-01
20090005210INTERNAL TRANSMISSION HUB ASSEMBLY - A multi-speed internal bicycle hub transmission assembly includes a hub axle, a driver, a hub shell, a power transmission mechanism and a shift control mechanism. The driver and the hub shell are rotatably supported to the hub axle. The power transmission mechanism is disposed between the driver and the hub shell for transmitting rotational power from the driver to the hub shell. The shift control mechanism includes a shift controller and a positioner. The shift controller is movable in rotational directions relative to the hub axle to a plurality of orientations. Each orientation of the shift controller corresponds to selection of a corresponding one of plurality of power transmission paths of the power transmission mechanism. The positioner is non-movable in the rotational direction relative to the hub axle and is biased into contact with the shift controller.2009-01-01
20090005211BICYCLE HUB TRANSMISSION - A bicycle hub transmission basically includes a hub axle, a driver, a hub shell, a power transmission mechanism and a shift mechanism. The driver is rotatably supported relative to the hub axle. The hub shell is rotatably supported relative to the driver. The power transmission mechanism includes a downstream planetary gear unit and an upstream planetary gear unit disposed between the driver and the hub shell to selectively transmit rotational power from the driver to the hub shell through one a plurality of power transmission paths. The shift mechanism is operatively coupled to the power transmission mechanism to select one of the power transmission paths. The downstream planetary gear unit includes at least a planetary gear carrier that meshes with planetary gears of the upstream planetary gear unit.2009-01-01
20090005212ONE WAY CLUTCH AND SYNCHRONIZER ASSEMBLY - A one way clutch and synchronizer assembly includes a stationary member having a plurality of clutch struts and camming surfaces, a second circular selector member, an third rotating controlled member and a fourth stationary member. The selector member includes apertures or windows through which the clutch struts may pass to engage the rotating member and camming surfaces which provide a selective frictional coupling between the stationary members and the rotating member. A bidirectional hydraulic or electric actuator selectively, bi-directionally rotates the selector member.2009-01-01
20090005213Planetary gear mechanism - The invention proceeds from a planetary gear mechanism having at least one drive unit (2009-01-01
20090005214METHOD FOR REDUCING TORQUE REQUIRED TO CRANK ENGINE IN HYBRID VEHICLE - A method of operating a hybrid powertrain system is provided for a vehicle that includes an internal combustion engine having an engine output to drive the vehicle and a motor having a motor output to drive the vehicle. The motor is operatively connected to the engine and operable to crank the engine. The method includes the steps of reducing compression in at least one engine cylinder and operating the motor to crank the engine. A hybrid powertrain system for a hybrid vehicle is also provided.2009-01-01
20090005215Double step gear shifting in a hybrid electric vehicle - In a powertrain for a vehicle that includes an engine, a transmission having an input, a current gear, an input clutch, a target gear and an output for driving a load, and an electric machine for driving the load, a method for performing a gearshift from the current gear to the target gear comprising the steps of opening the input clutch, releasing a drive connection between the current gear and the output, producing a drive connection between the target gear and the output, using the electric machine to produce torque at the load, closing the input clutch; and reducing the torque produced by the electric machine.2009-01-01
20090005216METHODS AND SYSTEMS TO FEEDBACK COORDINATED TORQUE CONTROL SYSTEM INFORMATION - An engine control system comprises a first torque request module that generates a first torque request, a second torque request module that generates a second torque request, a torque arbitration module, an arbitration feedback module, and a torque control module. The torque arbitration module selects one of the first and second torque requests and outputs an arbitrated torque based on the selected one of the first and second torque requests. The arbitration feedback module reports a status signal to the first torque request module. The status signal has a first value when the first torque request is the selected one of the first and second torque requests. The torque control module controls an engine to produce the arbitrated torque. The power source includes an internal combustion engine.2009-01-01
20090005217TRANSMISSION UPSHIFT FLARE DETECTION AND MITIGATION - A transmission control module comprises an actuation module and a flare control module. The actuation module controls actuation of a friction device used in shifting from a first transmission ratio to a second transmission ratio. The transmission ratio is based on an input speed of a transmission divided by an output speed of the transmission. The first transmission ratio is greater than the second transmission ratio. The flare control module selectively generates an engine torque reduction request when a measured transmission ratio is greater than a threshold during a shift from the first transmission ratio to the second transmission ratio.2009-01-01
20090005218SYSTEMS AND METHODS FOR NON-LINEAR PROPORTIONAL AND DERIVATIVE CONTROL DURING VEHICLE GARAGE SHIFTS - The present disclosure utilizes Non-linear Proportional and Derivative (NLPD) control on a duty cycle of an applying clutch for stationary and rolling vehicle garage shifts. The applying clutch can be engaged by as electrically activated solenoid valve, and the present disclosure utilizes NLPD control to adjust the duty cycle of the solenoid to provide a smooth vehicle garage shift engagement. The present disclosure utilizes a control algorithm based on turbine speed, turbine acceleration, and output speed. The present disclosure can utilize an existing vehicle control unit, such as an engine control unit (ECU), transmission control unit (TCU), or the like, to receive turbine speed measurements, to calculate the solenoid duty cycle using NLPD control on the turbine speed acceleration error, and to adjust the solenoid driver on the solenoid valve.2009-01-01
20090005219Work Vehicle - A work vehicle operable in a rearward facing position using a simple construction is disclosed. The work vehicle includes a hydrostatic stepless change speed device for transmitting power from an engine to a traveling device, a change speed pedal mechanism operable in a forward facing position for changing speeds in the hydrostatic stepless change speed device, and a travel-control lever provided at a rear position of a vehicle body and operable in the rearward facing position. The travel-control lever and the change speed pedal mechanism are linked to each other through a mechanical interlocking mechanism so as to control the hydrostatic stepless change speed device by the travel-control lever through the change speed pedal mechanism.2009-01-01
20090005220Mobile Communication Terminal Having Exercise Quantity Measurement Function and Method of Measuring Exercise Quantity Using the Same - Disclosed is a method of measuring the amount of exercise using a mobile communication terminal equipped with an acceleration sensor capable of measuring movement of a user. The method includes the steps of: a) measuring acceleration according to a change in the location of the mobile communication terminal by the acceleration sensor and detecting acceleration values of the terminal expressed in an orthogonal coordinate system where the acceleration sensor is set to a reference position; b) calculating gravitational acceleration direction values of the acceleration of the terminal from the acceleration values of the terminal detected in step a); c) detecting relative values of the acceleration values with respect to the gravitational acceleration direction values; and d) calculating the movement amount from the detected relative values.2009-01-01
20090005221 Trampoline - The invention comprises a trampoline including a flexible mat, a plurality of resiliently flexible rods each having a lower end retained in a frame of the trampoline and an enlarged upper end, and a plurality of fittings coupled to the mat about a periphery of the mat and including on or in an underside of each fitting a socket cavity which receives the upper end of a flexible rod so that the upper ends of the flexible rods are pivotally connected to the periphery of the mat, the fitting also including an entry into the socket cavity for the enlarged upper end of the flexible rod through an upper side of the fitting and a restricted entry towards the socket cavity for a part of the flexible rod below said enlarged upper end and through which the rod upper end cannot pass, to one side of the fitting and defined between opposed side or underside parts of the fitting.2009-01-01
20090005222Stationary exercise apparatus - A stationary exercise device with adjustable members for varying the stride path and the exercise intensity of a user. The stationary device having a stationary frame and a movable frame that moves relative to the stationary frame to vary the exercise intensity of a user.2009-01-01
20090005223Back twister - A Back Twister comprises: 2009-01-01
20090005224FOLDABLE TREADMILL - A foldable treadmill comprising a base bracket, a deck coupled to the base bracket for moving between a use position and a stored position, a support post extending upwardly and movably coupled to the deck, and a handle pivotally connected to the support post. A handle linkage can be coupled to the handle, and a lifting device can be coupled between the base bracket and the handle linkage for moving the handle when the deck is being moved. In one embodiment, the lifting device includes a support rod coupled to the support post and a deck rod coupled between the base bracket and the support rod. In this embodiment, the support rod has a first portion slidably coupled to the deck and another portion coupled to the handle linkage. The treadmill can further include a control panel movably coupled to the top portion of the support post. Preferably, a link bar is coupled between the control panel and the handle for moving the control panel when the deck is being moved.2009-01-01
20090005225CHARGING ROLL - A charging roll includes a shaft and an ionically conductive elastic layer formed around the shaft. The ionically conductive elastic layer is formed of a rubber composition free of any electron-conductive agent and containing 0.7 to 1.0 parts by weight of a peroxide cross-linking agent per 100 parts by weight of an ion-conductive rubber. The ion-conductive rubber is formed of at least one of an epichlorohydrin rubber and a nitrile rubber, and a percentage of a rubber component in the ionically conductive elastic layer measured by thermogravimetric analysis is 90% or more by weight.2009-01-01
20090005226PACKAGING MACHINE WITH GLUING STATION AND FOLDING STATION - An apparatus for forming an end closure structure of a carton. The end closure structure is formed from minor end flaps and major end flaps. The apparatus includes a carton conveyor for transferring the carton in a flow direction along a carton conveyor path, a major end flap retaining guide assembly for retaining the major end flaps in an outwardly upright position, a minor end flap retaining guide assembly for retaining the minor end flaps in an inwardly folded position, and a gluing station for applying adhesive to the major and minor end flaps.2009-01-01
20090005227Folding Assembly and Method for Producing a Gable Portion of a Sealed Package of a Pourable Food Product - A folding assembly for producing a gable portion of a sealed package of pourable product, wherein the gable portion has first and second walls sloping with respect to each other and joined at a seal, and a flap connecting lateral edges of the first and second walls. The folding assembly is supplied with packs, each having an axis and, at one end and on opposite sides of the axis, two end portions which are folded to form the gable portion, with the end portions having, respectively, a first and a second portion to be folded, which are joined by a lateral face of the pack. The folding assembly includes a folding mechanism which interacts, on opposite sides of the axis, with the first and second portion of the pack to fold the second portion onto the lateral face, and the first portion onto the second portion to form the flap.2009-01-01
20090005228Method and Device for Manufacturing Bag with Clamping Device2009-01-01
20090005229BOOKLETMAKER NIP-IDLER ASSIST CREASING DEVICE - An assembly to crease a paper set in a booklet maker is provided. A booklet is formed in a booklet marker when a crease blade strikes the middle of the stack and pushes it toward a set of nipped crease rolls. The assembly engages spring-loaded idlers against the crease rolls after the crease blade initiates the buckle of the stack and prior to creasing. The spring loaded idlers apply a drive force to the stack that assists the formation of the crease. With the assistance of this extra drive force, the crease blade tip can be stopped in time to avoid jamming while reducing the chance of getting a cover, or more sheets tearing off the booklet. This design is compact in size and therefore may also be retrofitted into existing designs.2009-01-01
20090005230Centrifuge - A centrifuge with an electric motor (2009-01-01
20090005231Method and apparatus for separating cooking oils from snack food products through a quasi-continuous centrifuge action - A centrifuge operative in successive low speed and high speed modes serves to remove surface cooking oil from a continuous stream of fragile snack food products wherein the oil removal occurs in the high speed mode and products are discharged from the centrifuge with relatively low kinetic energy in the low speed mode.2009-01-01
20090005232Composite Structures having Reinforced Edge Bonded Joints and Method for Making the Same - A ceramic matrix composite structure has a reinforced core for carrying loads. The core includes a web connected between the facesheets by edge bonded joints for transmitting compressive, tensile and shear loads. The edge bonded joints are laterally reinforced by bridging members bonded to the facesheets, on opposite sides of the webs The bridging members may comprise low density, high temperature rigid foam.2009-01-01
20090005233Component with a ceramic coating, into which particles are embedded, and method for producing said component - The subject matter of the invention is a component which is provided with a ceramic coating forming the surface. Inventively there is provision at least in a cover layer of the coating for nanoparticles made from a colorant (CrCoAl or a spinel-type oxide) and aluminum oxide nanoparticles. This combination of nanoparticles in the coating advantageously results in a resistance to high temperatures of the coloring of the surface of up to 1000° C. not previously known. This allows even components under great stress, such as for example compressor or turbine blades of a gas turbine, to be provided with temperature-resistant coloring. This can then be used for an optical inspection for example. Protection is also claimed for a method for creating the inventive coating2009-01-01
20090005234Photocatalytic material - A photocatalytic material which comprises a resin base and photocatalyst particles tenaciously deposited thereon in such a manner that the function of the photocatalyst is not impaired. Even when the photocatalytic material is used over long, the photocatalyst particles are less apt to shed and the resin base is less apt to deteriorate. In the photocatalytic material, the photocatalyst particles have been bonded to the base by chemical bonding through a silane compound. The photocatalytic material is characterized in that the chemical bonding through a silane compound is bonding by graft polymerization, and that the graft polymerization is radiation-induced graft polymerization.2009-01-01
20090005235Method of recycling spent flue gas denitration catalyst and method of determining washing time of spent flue gas denitration catalyst - The present invention provides a method of recycling a spent flue gas denitration catalyst and a method of determining a washing time of the spent flue gas denitration catalyst. The method of recycling the spent flue gas denitration catalyst includes physically removing solids deposited in the spent flue gas denitration catalyst, removing poisoning substances deposited in the spent flue gas denitration catalyst by washing the spent flue gas denitration catalyst with a washing liquid for a washing time determined by measuring the hydrogen ion concentration of the washing liquid and drying the resulting spent flue gas denitration catalyst.2009-01-01
20090005236Mesostructured Zeolitic Materials and Methods of Making and Using the Same - One aspect of the present invention relates to mesostructured zeolites. The invention also relates to a method of preparing mesostructured zeolites, as well as using them as cracking catalysts for organic compounds and degradation catalysts for polymers.2009-01-01
20090005237Method for preparing the mixed electrode catalyst materials for a PEM fuel cell - The present invention relates to a process for preparing electrode catalyst materials for a polymer electrolyte membrane fuel cell (PEMFC), and particularly to a high-performance platinum-non-platinum mixed electrode catalyst (Pt—RuOs/C) having a physically mixed structure of RuOs alloy and platinum materials, which is prepared by adding a small amount of platinum (Pt) to RuOs alloy materials highly dispersed on a carbon support, where the amount of platinum used is drastically reduced as compared to the conventional platinum materials, thus lowering the manufacturing cost.2009-01-01
20090005238Modified Nanostructured Titania Materials and Methods of Manufacture - Provided is a method for synthesising a substantially size homogenous composition of titanium (IV) oxide (titania) nanoparticles comprising, synthesising a titania inorganic crystalline matrix within a sol gel reaction process under conditions that constrain the growth of the matrix such that a majority of the nanoparticles are of a narrow size distribution in the composition and do not exceed a maximum diameter of around 100 nm. The sol gel reaction process can occur under aqueous conditions, or within an organic polymer matrix under non-aqueous conditions. Aqueous dispersions and pastes comprising the substantially size homogenous composition of titanium (IV) oxide nanoparticles are also provided. The titanium (IV) oxide nanoparticles demonstrate improved photoactivity when exposed to UV irradiation, and can also include visible light absorbing centres such that activity is extended into the visible light range.2009-01-01
20090005239Zirconium Hydroxide - This invention relates to an improved amorphous zirconium hydroxide and a method for its production. The hydroxide has a surface area of at least 300 m2009-01-01
20090005240CERAMIC STRUCTURE AND PROCESS FOR PRODUCING THE SAME - There is disclosed a ceramic structure which comprises a material having a controlled pore distribution and including cordierite as the main crystal phase. In the pore distribution, the volume of pores having pore diameters smaller than 20 μm accounts for 15% or less of the total pore volume, and the volume of pores having pore diameters of 20 to 100 μm accounts for 70% or more of the total pore volume. This ceramic structure is suitable for realizing a ceramic catalyst body which has excellent purification efficiency, is reduced in pressure loss, and is mountable even in a limited space.2009-01-01
20090005241Purification Catalyst for Exhaust Gas, Production Method Therefor, and Purification Catalyst Equipment for Exhaust Gas - A purification catalyst for exhaust gas which exhibits satisfactory performance even at a low temperature operation of starting or idling of engine (not more than 400° C.), and a production method therefor are provided.2009-01-01
20090005242Catalyst for Synthesizing Hydrocarbons C5-C100 and Method of Preparation Thereof - The invention relates to petroleum, gas, and coal chemistry, especially to catalysts for C2009-01-01
20090005243Doped metal organic frameworks for reversible H2 storage at ambient temperature - Metal-organic frameworks (MOFs) are provided. An exemplary MOF includes a plurality of metal clusters, at least one linking ligand, and at least one dopant. Doped MOFs according to embodiments of the present invention have significantly increased H2 uptake capacity, and some embodiments meet the 2010 DOE H2 storage target of 6 wt % at a temperature ranging from −30 to 80° C. and a pressure less than or equal to 100 bar.2009-01-01
20090005244DYE RECEPTIVE POLYMER COATING FOR GRAPHIC DECORATION - An image receptive medium comprising a semi-translucent polymer containing semi-translucent particulate capable of attenuating visible light and imparting color or haze is disclosed. The image receptive medium includes an image receiving layer containing particulate with various light attenuating properties. The image receiving layer can receive a dye through sorption or diffusion. The attenuating properties of the particulate act to enhance the quality of the image by obscuring background and scattering light to illuminate the dye. The result is a durable image requiring only a single layer which is highly visible on opaque, clear, or colored substrates.2009-01-01
20090005245Manufactured seed having a live end seal coating - An artificial seed is provided. The artificial seed includes a seed shell having a cavity sized and configured to receive an embryo. The artificial seeds also includes a live end seal and a tertiary seal. The live end seal is attached to the seed shell and is positioned to substantially seal the embryo within the seed shell. The tertiary seal is attached to the live end seal and includes a pesticide additive to inhibit at least bacterial growth on the tertiary seal.2009-01-01
20090005246Herbicidal Composition - A herbicidal composition in the form of an emulsifiable concentrate which comprises, in addition to emulsifiers and water-insoluble solvents, 2,2-dimethyl-propionic acid 8-(2,6-diethyl-4-methyl-phenyl)-9-oxo-1,2,4,5-tetrahydro-9H-pyrazolo[1,2-d][1,4,5]oxadiazepin-7-yl ester and an alcohol.2009-01-01
20090005247Dispenser and Methods for Dispensing Custom Garden Products - An apparatus for diagnosing a plant ailment and providing a formulation to address the plant ailment is shown and described along with a method of identifying a plant ailment, dispensing a formulation for the ailment and for applying the formulation to the plant are disclosed. The formulation dispenser is a multiple-component liquid and powder material dispenser with multiple pump types and reservoirs or canisters. All of the pumps are controlled by a central controller which also preferably includes substantial memory for a database containing a library of formulations associated with particular plant ailments. Samples of the sick plants may be scanned or digital photographs downloaded into the memory for diagnosis. Experts can be consulted over the internet or telephone for assistance in identifying an appropriate formulation. A limited quantity of the formulation is prepared for a single application and deposited in a recyclable container. The entire formulation is intended to be applied and the container disposed of thereby eliminating the presence of hazardous materials in the consumer's garage or garden shed. The dispensed formulations may be in granular, liquid or concentrate form.2009-01-01
20090005248SYNERGISTIC HERBICIDAL COMPOSITION CONTAINING A SUBSTITUTED PHENOXY ALKANOIC ACID DERIVATIVE AND A GLYPHOSATE DERIVATIVE - An herbicidal composition containing (a) an herbicidal substituted phenoxy alkanoic acid derivative component and (b) an herbicidal glyphosate component provides synergistic control of selected weeds.2009-01-01
20090005249METHOD AND COMPOSITION FOR CONTROLLING WEEDS - The present invention is directed to a novel composition for controlling grassy weeds which includes the combination of a preemergent grassy weed herbicide with a post emergent grassy weed herbicide and to a method of controlling such weeds with the novel composition. The present invention is also directed to a novel composition for controlling grassy weeds and, optionally broadleaf weeds, which novel composition includes the combination of a preemergent grassy weed herbicide, a post emergent grassy weed herbicide and a three-way phenoxy herbicide, and to a method of controlling such grassy weeds and, optionally such broadleaf weeds, with the novel composition. The present invention has been found to be particularly useful for the control of crabgrass in cool season grasses and mixtures of cool season grasses.2009-01-01
20090005250Substituted 2,4-diamino-1,3,5-triazines, processes for their use as herbicides and crop growth regulators - Compounds of the formula (I) or salts thereof, in which2009-01-01
20090005251Superconducting element containing MgB2 - A superconductive element containing magnesiumdiboride (=MgB2009-01-01
20090005252High throughput genome sequencing on DNA arrays - The present invention is directed to methods and compositions for acquiring nucleotide sequence information of target sequences using adaptors interspersed in target polynucleotides. The sequence information can be new, e.g. sequencing unknown nucleic acids, re-sequencing, or genotyping. The invention preferably includes methods for inserting a plurality of adaptors at spaced locations within a target polynucleotide or a fragment of a polynucleotide. Such adaptors may serve as platforms for interrogating adjacent sequences using various sequencing chemistries, such as those that identify nucleotides by primer extension, probe ligation, and the like. Encompassed in the invention are methods and compositions for the insertion of known adaptor sequences into target sequences, such that there is an interruption of contiguous target sequence with the adaptors. By sequencing both “upstream” and “downstream” of the adaptors, identification of entire target sequences may be accomplished.2009-01-01
20090005253Double Hybrid System Based on Gene Silencing by Transcriptional Interference - The invention relates to a novel double hybrid system and to the uses thereof. This system provides, in particular, a tool that enables the detection of the interruption of a protein-protein interaction. The developed system uses transcription interference as a mechanism for detecting a breaking up of interacting protein pairs. The developed double hybrid system can be applied to the screening of molecules enabling the detection of molecules breaking up a protein-protein interaction as well as enabling the identification of alleles lacking in the interaction of proteins involved in the protein-protein interactions.2009-01-01
20090005254Compartmentalized Screening by Microfluidic Control - The invention describes a method for the identification of compounds which bind to a target component of a bio-chemical system or modulate the activity of the target, comprising the steps of: a) compartmentalising the compounds into micro-capsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsule; and b) identifying the compound which binds to or modulates the activity of the target; wherein at least one step is performed under microfluidic control. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development.2009-01-01
20090005255METHOD FOR DETECTING TARGET BIOLOGICAL MATERIAL USING DNA BARCODES - A method for detecting a target biological material using DNA barcodes is provided. The method comprises: attaching a first type of probes to the surface of magnetic particles to prepare magnetic particles for isolation wherein the first type of probes are at least partially complementary to a target biological material of interest; attaching a second type of probes to the surface of polymer particles to prepare polymer particles for analysis wherein the second type of probes are at least partially complementary to the target material but are different from the first type of probes, and attaching DNA barcodes as identification codes to the surface of the polymer particles wherein the DNA barcodes are present in an amount at least three times the amount of the second type of probes, have a predetermined sequence and are labeled with a label material; reacting the magnetic particles for isolation, the polymer particles for analysis and the target material in a hybridization reaction buffer to prepare composites, each of which consists of one magnetic particle for isolation, the target material and one polymer particle for analysis; separating the composites from unreacted reactants using a magnetic separator; heating the separated composites to denature the DNA barcodes present in the polymer particles for analysis and removing the magnetic particles for isolation and the polymer particles for analysis from the composites by centrifugation to isolate the DNA barcodes; and detecting a signal generated from the label material bound to the isolated DNA barcodes.2009-01-01
20090005256Analysis of Encoded Chemical Libraries - The invention provides methods and compositions for analysis of a mixture of DNA sequences. More particularly, the invention provides methods and compositions for analysis of encoded chemical libraries having encoding nucleic acid tags (e.g., encoded chemical libraries prepared by nucleic acid-mediated chemistry) through analyzing the nucleic acid templates.2009-01-01
20090005257Process for Recovering Polypeptides that Unfold Reversibly from a Polypeptide Repertoire - The invention relates to polypeptides that unfold reversibly (e.g., unfolds when heated and refolds when cooled), to repertoires containing polypeptides that unfold reversibly and to libraries that contain polypeptides that unfold reversibly or nucleic acids that encode polypeptides that unfold reversibly. The invention further relates to processes for producing a library enriched in polypeptides that unfold reversibly or nucleic acids encoding polypeptides that unfold reversibly, processes for selecting and/or isolating polypeptides that unfold reversibly, and to methods for producing a polypeptide that unfolds reversibly.2009-01-01
20090005258Diagnosis of Metastases in Hnscc Tumours - The invention relates to the detection or prediction of metastases of head and neck squamous cell carcinoma (HNSCC) with the use of gene expression profiles. A gene signature has been identified which is able to detect or predict the occurrence of these metastases better than current clinical methods. Part of the invention are micro-arrays comprising this signature and methods for performing the detection and/or prediction.2009-01-01
20090005259Random array DNA analysis by hybridization - The invention relates to methods and devices for analyzing single molecules, i.e. nucleic acids. Such single molecules may be derived from natural samples, such as cells, tissues, soil, air and water without separating or enriching individual components. In certain aspects of the invention, the methods and devices are useful in performing nucleic acid sequence analysis by probe hybridization.2009-01-01
20090005260MULTIPLEX DATA COLLECTION AND ANALYSIS IN BIOANALYTE DETECTION - Method and device to collect multiplex data simultaneously in analyte detection and analyze the data by experimentally trained software (machine-learning) is disclosed. Various ways (magnetic particles and microcoils) are disclosed to collect multiple reporter (tag) signals. Multiplex detection can increase the biomolecule analysis efficiency by using small sample size and saving assay reagents and time. Machine learning and data analysis schemes are also disclosed. Multiple affinity binding partners, each labeled by a unique reporter, are contacted with a sample and a single spectrum is taken to detect multiple reporter signals. The spectrum is deconvoluted by experimentally trained software to identify multiple analytes.2009-01-01
20090005261PURIFICATION OF IMMUNOGLOBULINS USING AFFINITY CHROMATOGRAPHY AND PEPTIDE LIGANDS - An immunoglobulin binding peptide having the general formula, from amino terminus to carboxy terminus, of Z-R2009-01-01
20090005262Methods, Compositions and Compound Assays for Inhibiting Amyloid-Beta Protein production - A method for identifying compounds that inhibit amyloid-beta precursor protein processing in cells, comprising contacting a test compound with a GPCR polypeptide, or fragment thereof, and measuring a compound-GPCR property related to the production of amyloid-beta peptide. Cellular assays of the method measure indicators including second messenger and/or amyloid beta peptide levels. Therapeutic methods, and pharmaceutical compositions including effective amyloid-beta precursor processing-inhibiting amounts of GPCR expression inhibitors, are useful for treating conditions involving cognitive impairment such as Alzheimers Disease.2009-01-01
20090005263Signal Amplification of Biorecognition Events Using Photopolymerization in the Presence of Air - The present invention discloses an inexpensive and non-enzymatic signal amplification technique on both DNA and protein microarrays. The technique is uses photo-initiated polymerization and is conducted directly on the microarray. A capture molecule is bound to the desired surface. The target molecule then binds to the capture molecule. A label sequence with a bound photo initiator binds to the target molecule. Polymerization is activated using a wave length of light corresponding to the wave length needed to activate the chosen photo initiator. This new non-enzymatic method can be applied to the rapid detection of any biological pathogen via either microarray or ELISA platforms. Influenza is described herein as an example application of the technology.2009-01-01
20090005264CELL SURFACE DISPLAY, SCREENING AND PRODUCTION OF PROTEINS OF INTEREST - Aspects of the invention provide compositions and methods for displaying engineered polypeptides on a cell surface. According to aspects of the invention, immobilized polypeptides can be screened to identify one or more variants having one or more functional or structural properties of interest. Aspects of the invention provide composition and methods for producing engineered protein or protein variants having a functional or a structural property of interest.2009-01-01
20090005265METHOD OF ISOLATING NUCLEIC ACID USING MATERIAL POSITIVELY CHARGED AT FIRST PH AND CONTAINING AMINO GROUP AND CARBOXYL GROUP - A method of isolating nucleic acid from a sample containing nucleic acid is provided. The method includes contacting the sample with a bifunctional material that contains an amino group and a carboxyl group and is positively charged at a first pH to allow binding of the nucleic acid to the bifunctional material; and extracting the nucleic acid at a second pH higher than the first pH from the complex.2009-01-01
20090005266Methods for Making and Using Molecular Switches Involving Circular Permutation - The invention provides molecular switches which couple external signals to functionality, and combinatorial methods of making and using the same involving circular permutation of nucleic acid and amino acid sequences. The switches according to the invention can be used, for example, to regulate gene transcription, target drug delivery to specific cells, transport drugs intracellularly, control drug release, provide conditionally active proteins, perform metabolic engineering, and modulate cell signaling pathways. Libraries comprising the switches, expression vectors and host cells for expressing the switches are also provided.2009-01-01
20090005267IMMUNOASSAY FOR CROSS-REACTING SUBSTANCES - The present disclosure provides an immunoassay involving a multiplex of antibodies that recognize the same analyte but that have a different cross-reactivity to structurally similar compounds. Data obtained from the immunoassay involving observed analyte concentrations is input into an algorithm to determine the true concentration of the analyte in a sample.2009-01-01
20090005268Compositions and Methods for Cancer Diagnostics Comprising Pan-Cancer Markers - The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, so-called “pan cancer markers”. In particular, the present invention provides methods of identifying methylation patterns in genes associated with specific cancers, and their related uses. In another aspect, the present invention provides methods of selecting and combining useful sets of pan cancer markers.2009-01-01
20090005269Novel Silane Compounds and Their Use in Functionalizing Solid Supports and Immobilizing Biological Molecules on These Supports - The invention relates to novel silane compounds corresponding to the following formula (I):2009-01-01
20090005270Systems and Methods for Evaluating Enzyme Competency - The present invention provides systems and methods for determining enzymatic competency, which is important in determining whether a patient may suffer an adverse drug reaction, has a disease associated with defects in specific enzymatic function, and/or has an enzyme defect that is likely to cause pathophysiology. As contemplated herein, a parent molecular entity is administered to a patient in whom enzymatic competency is to be determined. A sample of the patient's bodily fluid is exposed to a sensor of the invention to distinguish, detect, and quantify a detectable entity in the bodily fluid. Sensor-acquired data regarding the detectable entity is used to determine enzymatic competency. Preferably, a sample of a patient's exhaled breath is collected and exposed to the sensor of the invention. Types of sensor systems of the invention include, but are not limited to, surface resonance arrays; microelectromechanical sensors (such as microcantilever-based technology); molecularly imprinted polymer sensors; amplifying fluorescent sensor technology; aptamer-based sensor technology; SAW sensors; infrared sensors; fuel cells; chemical reactors; and pH sensitive sensors.2009-01-01
20090005271REDUCED ABRASIVENESS WITH MICRONIZED WEIGHTING MATERIAL - A method of prolonging the average lifespan of downhole tools that includes circulating the wellbore fluid comprising a base fluid and at least one of a micronized weighting agent and a dispersant coated weighting agent through the wellbore; wherein the wellbore fluid is characterized as having at least one of an equivalent weight, an equivalent or lower settling rate, and an equivalent or lower sag than a baseline wellbore fluid comprising a base fluid and an API-grade barite weighting agent; and wherein the wellbore fluid reduces abrasive wear of the downhole tool as compared to drilling with the baseline wellbore fluid is disclosed.2009-01-01
20090005272Grease Composition, Grease-Enclosed Bearing, and One-Way Clutch - The present invention provides a grease composition capable of effectively preventing a rolling surface from having hydrogen brittleness-caused peeling, a grease-enclosed bearing in which the grease composition is enclosed, and a one-way clutch in which the grease composition is enclosed at a sliding portion. The grease composition contains a base grease consisting of a base oil and a thickener and an additive added to the base grease. The grease composition is capable of preventing hydrogen brittleness-caused peeling from occurring on a frictionally worn surface of a bearing portion containing an iron-based metal material or a newly generated surface consisting of the iron-based metal material exposed owing to wear. The additive contains at least one aluminum-based additive selected from among an aluminum powder and inorganic aluminum compounds. The mixing ratio of the aluminum-based additive to 100 parts by weight of the base grease is set to 0.05 to 10 parts by weight.2009-01-01
20090005273FUNCTIONAL FLUID COMPOSITIONS - A functional fluid comprising a base oil with a high viscosity index, wherein the functional fluid has a kinematic viscosity at 100° C. between 2.5 and 5.0 mm2009-01-01
20090005274PROCESS FOR MAKING SHOCK ABSORBER FLUID - A process to make a shock absorber fluid having improved performance properties, the properties including an air release after 1 minute by DIN 51381 of less than 0.8 vol %, a kinematic viscosity at 100° C. less than 5 mm2009-01-01
20090005275Power steering fluid - Provided are power steering fluids made from a waxy feed and with improved low temperature properties, such as, for example, a viscosity index of greater than 290 and a Brookfield Viscosity at −40° C. of less than 1900 mPa·s. In an embodiment, the power steering fluid comprises greater than 50 weight % base oil, viscosity index improver, and less than about 1.0 weight % pour point depressant.2009-01-01
20090005276Boron-Containing Lubricating Oils Having Improved Friction Stability - Lubricating oil compositions having excellent friction stability comprise a base lubricating oil, an oil soluble source of phosphorus and a defined polyalkylene polyamine-based friction modifier that has been reacted with a borating agent to convert at least one secondary amine group into the corresponding boric acid ester or boric acid salt.2009-01-01
20090005277Lubricating Oils Having Improved Friction Stability - Lubricating oil compositions having excellent friction stability comprise a base lubricating oil, an oil soluble source of phosphorus and a defined polyalkylene polyamine-based friction modifier that has been reacted with an acylating agent to convert at least one secondary amine group into an amide.2009-01-01
20090005278FUEL ECONOMY LUBRICATING OIL COMPOSITION FOR LUBRICATING DIESEL ENGINES - A lubricating oil composition for internal combustion engines comprising a base oil having and lubricating viscosity and additives composed of a) a salt of an alkali metal or alkaline earth metal and an alkylsalicylate and/or an alkylcarboxylate, b) a nitrogen atom-containing ashless dispersant and/or a nitrogen atom-containing dispersive viscosity index improver, c) a neutral salt of a fatty acid and a fatty amine, and d) oxidation inhibitor, is effective for lubricating diesel engines using a low sulfur-content fuel, even though it has a low sulfated ash content, a low sulfur content and a low phosphorus content.2009-01-01
20090005279 Polyalpha-Olefin Compositions and Processes to Produce the Same - This invention relates to a polyalpha-olefin (and hydrogenated analogs thereof) comprising more than 50 mole % of one or more C5 to C24 alpha-olefin monomers where the polyalpha-olefin has: a) 40 mole % or more of mm triads, b) a Bromine number of Y or greater, where Y is equal to 89.92*(V)′°5863, where V is the Kinematic Viscosity of the polyalpha-olefin measured at 100° C. in cSt, and c) 1,2 disubstituted olefins present at 7 mole % or more, preferably having Z mole % or more of units represented by the formula: where j, k and m are each, independently, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, or 22, n is an integer from 1 to 350, and where Z=8.420*Log(V)−4.048, where V is the kinematic viscosity of the polyalpha-olefin measured at 1000 C in cSt This invention also relates to process to produce such polyalpha-olefins.2009-01-01
20090005280PERFUMED HOUSEHOLD PRODUCTS AND METHODS FOR PRESERVING PERFUME INTEGRITY AND EXTENDING FRAGRANCE LIFE - Household cleaning, fabric treatment, or deodorizing products and methods of preserving the integrity of hydrophilic perfume ingredients and extending fragrance life are disclosed. The product and method include an aqueous composition containing a surfactant and a perfume having a substantial proportion of hydrophilic perfume ingredients with a Clog P of less than about 3 and a boiling point greater than about 200° C. The aqueous composition may be contained in plastic containers constructed of hydrophilic perfume compatible materials. The invention preserves perfume integrity by decreasing migration of hydrophilic perfume ingredients into and/or transmission through plastic containers and extends fragrance life once the hydrophilic perfume ingredients are deposited onto a surface.2009-01-01
20090005281Compositions Containing Amine Oxide Surfactants or Soil Penetration Agents - The compositions of the present invention relate to improved shampoo compositions having from about 5 to about 50 wt. % of a detersive surfactant composition comprising at least one anionic surfactant, from about 0.1 to about 20 wt. % amine oxide, and from about 0.01 to about 5 wt. % cationic polymer, where the molar ratio of anionic surfactant to amine oxide is about 2:1 to about 40:1. The compositions of the present invention also relate to improved shampoo compositions having from about 5 to about 50 wt. % of a detersive surfactant composition, from about 0.1 to about 20 wt. % amine oxide, from about 0.01 to about 5 wt. % cationic polymer, and from about 0.1 to 10 wt. % soil penetration agent.2009-01-01
20090005282Replacement Solvents Having Improved Properties and Methods of Using the Same - CFC replacement solvent compositions, methods of using the same and methods of making the same. These compositions meet or exceed the solvency, flammability, and compatibility requirements for CFC's while providing similar or improved environmental and toxicological properties. These solvent compositions have applications including, but not limited to, oxygen handling, refrigeration or heat pumps, electronics, implantable prosthetic devices, and optical equipment.2009-01-01
20090005283Stabilized, Non-Aqueous Cleaning Compositions for Microelectronics Substrates - Non-aqueous stripping and cleaning compositions for cleaning microelectronics devices, the composition having a least one organic sulfur-containing polar compound as a stripping solvent, at least one water-free source of a strong hydroxide base, and at least one hydroxypyridine stabilizing agent to inhibit detrimental side reactions.2009-01-01
20090005284Cleaning Product for Rugs, Fabrics and Carpets - The invention relates to an aqueous base formulation for cleaning rugs, fabrics, carpets, and the like. The formulation is composed of seventy-eight point five percent water, to which is added tetrapotassium pyrophosphate at ten percent of the formulation. A nonionic surfactant, ethoxylated glycery) ricinoleate, is then added at three percent. An isopropyl alcohol is then added at three percent. A fifth product, propylene carbonate, is introduced at five percent. Finally, sodium cumene sulphonate is added at zero point five percent. All these products are inserted with mechanized stirring so as to allow complete homogenization. There are no side effects for the user and the environment.2009-01-01
20090005285Composition For Treating Or Cleaning Fabrics - A composition for treating or cleaning fabric articles, especially articles of clothing, linen and drapery, wherein the composition comprises a lipophilic fluid, a polyalkyleneoxide polysiloxane surfactant, and a second surfactant.2009-01-01
20090005286Use of Cationic Polycondensation Products as Additives for Fixing Colours and/or Inhibiting the Running of Colours, for Washing Products and Washing Aftertreatment Products - The invention relates to the use of cationic polycondensation products as additives for fixing colours and/or inhibiting the running of colours, for washing products and washing aftertreatment products. Said cationic polycondensation products can be produced by the condensation of (A1) non-cyclic amines obtained by the reaction of (A1 a) mono(N,N-dialkylaminoalkyl)amines with (A1 b) bifunctional compounds selected from the group containing urea, thiourea, dialkyl carbonates, aliphatic and aromatic dicarboxylic acids, and aliphatic and aromatic diisocyanates, in a molar ratio 1.2:1 to 2.1:1, or (A2) mixtures of non-cyclic amines (A1) and cyclic amines (A3) in a molar ratio 10:1 to 1:10 with (B) bifunctional compounds selected from the group containing alkylene dihalogenides, dihalogen alkyl ethers, halomethyl oxiranes, and bisepoxides, in a molar ratio (B) to (A1) or (B) to (A2) from 0.6:1 to 1.3:1.2009-01-01
20090005287LAUNDRY DETERGENT COMPOSITIONS COMPRISING AMPHIPHILIC GRAFT POLYMERS BASED ON POLYALKYLENE OXIDES AND VINYL ESTERS - A laundry detergent composition comprising an amphiphilic graft polymer based on water-soluble polyalkylene oxides as a graft base and side chains formed by polymerization of a vinyl ester component, said polymer having an average of less than or equal to one graft site per 50 alkylene oxide units and a mean molar mass of from about 3,000 to about 100,000; from about 0.2% to about 8% of organic solvent; and from about 2% to about 20% of a surfactant system; wherein said detergent composition is in a form selected from: liquid; gel; and combinations thereof.2009-01-01
20090005288LAUNDRY DETERGENT COMPOSITIONS COMPRISING AMPHIPHILIC GRAFT POLYMERS BASED ON POLYALKYLENE OXIDES AND VINYL ESTERS - A laundry detergent composition comprising a graft copolymer of polyethylene, polypropylene or polybutylene oxide with vinyl acetate in a weight ratio of from about 1:0.2 to about 1:10; from about 0.2% to about 8% of organic solvent; and from about 2% to about 20% of a surfactant system; wherein said detergent composition is in a form selected from: liquid; gel; and combinations thereof.2009-01-01
200900052891,1,1,3,3- Pentafluorobutane Composition - The invention relates to the field of solvents. The invention relates more particularly to a composition based on 1,1,1,3,3-pentafluorobutane (HFC-365 mfc). The present invention also relates to a process for dissolving oil.2009-01-01
20090005290Extruded Personal Washing Bars With Plate-Like Inclusions - An extruded personal washing bar providing unique combination of sensory attributes, said bar comprising: 2009-01-01
20090005291Concentrated Fabric Conditioner Compositions - A method of making a fabric conditioning composition comprising providing: from 8 to 30% by weight of a quaternary ammonium softening material comprising a mixture of mono-ester, di-ester and tri-ester linked saturated components, a fatty complexing agent selected from fatty acids and fatty alcohols in an amount such that the weight of the mono-ester linked quaternary ammonium material to the fatty complexing agent is from 2.5:1 to 1:2, water, and perfume, the composition being free from non-ionic surfactant and added electrolyte, and subjecting the composition to a high shear and/or milling step.2009-01-01
20090005292Novel Peptides that Bind to the Erythropoietin Receptor - The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.2009-01-01
20090005293Methods and compositions for increasing the anaerobic working capacity in tissues - Provided are compositions comprising beta-alanylhistidine peptides and beta-alanines, and methods for administering these peptides and amino acids. In one aspect, the compositions and methods cause an increase in the blood plasma concentrations of beta-alanine and/or creatine.2009-01-01
20090005294Peptides for the Treatment of Cancer Associated with the Human Papilloma Virus (HPV) and Other Epithelial Tumors - This invention is related to the Molecular Pharmacology field and especially to the development of peptides useful for treating epithelial tumors and mainly those associated to oncogenic types of HPVs. The main objective of this invention is to identify peptides whose structure permits to block the Casein Kinase II (CKII) phosphorylation domain by direct interaction with such a site. In the present invention it is shown eleven cyclic peptides with different aminoacid sequences which inhibit the CKII phosphorylation in vitro, exhibit cytotoxicity on HPV-16 transformed cells (CaSki) and also increase the sensitivity of these cells to the cytostatic effect of interferon (IFN). Furthermore, the invention relates to the use of these peptides conjugated or fused to other peptides and chemical compounds which penetrates into cells as well as with the use of both peptide and chemical mimetic molecules.2009-01-01
20090005295Syndecans and angiogenesis - The invention provides methods and materials related to modulating syndecan levels and angiogenesis in an animal. The invention provides syndecan polypeptides and nucleic acids encoding syndecan polypeptides, including dominant negative syndecan polypeptides. The invention also provides polynucleotides and polynucleotide analogues for modulating angiogenesis, as well as cells and embryos containing the polynucleotides and polynucleotide analogues. The invention further provides methods for identifying syndecan- and angiogenesis-modulating agents.2009-01-01
20090005296Ammonium/Ammonia Transporter - The present invention relates to methods and means for ammonia and/or ammonium transport in a variety of organisms, including mammals, yeast and plants. In particular, the present invention is related to the use of isolated polypeptide molecules, which are particular members of the aquaporin superfamily, and isolated nucleic acid molecule that encode such polypeptides in the transport of NH2009-01-01
20090005297Aprotinin Variants - The present invention relates to the field of proteins that inhibit serine protease activity. The invention also relates to the field of nucleic acid constructs, vectors and host cells for producing serine protease inhibiting proteins, pharmaceutical compositions containing such proteins, and methods for their use.2009-01-01
20090005298Bone Sialoprotein Collagen-Binding Peptides - The present invention provides Novel collagen-binding peptides of bone sialoprotein (BSP). Peptides comprising a portion of the N-terminal collagen binding domain of BSP (residues 1-100) are used to stimulate mineralization, nucleate hydroxyapatite, and promote bone formation in collagen expressing tissues. Medicaments for use in the same are also contemplated. Chimeric and conjugate peptides comprising said collagen-binding BSP peptides are also included.2009-01-01
20090005299Method For Producing Carboxy-Terminal-Amidified Peptides - The invention relates to the production of carboxy-terminal (C-terminal) amidified peptides with C-terminal amidified lysin, in particular with the biological activity of GLP-1, the chemical and/or biotechnological precursors and intermediate products thereof. The invention also relates to a method for the production and use thereof for producing pharmaceutical products.2009-01-01
20090005300Antimicrobial Peptides and Methods of Use - Disclosed herein are novel antimicrobial peptides with useful, improved, or superior properties such as antimicrobial activity, desirable levels of hemolytic activity, and therapeutic index against a broad range of microorganisms including gram-negative and gram-positive bacteria and other organisms having a cellular or structural component of a lipid bilayer membrane. Also provided are methods of making and using such peptides to control microbial growth and in pharmaceutical compositions for treatment or prevention of infections caused by such microorganisms. Certain peptides are disclosed utilizing a structure-based rational design relating to an antimicrobial peptide, V2009-01-01