Entries |
Document | Title | Date |
20110008224 | Flow through cartridge for selecting an analyte online with high performance liquid chromatography - A flow through cartridge for solid phase extraction of an analyte from a liquid has a cartridge body bounding a passage for retaining a sorbent. The passage extends from a first end face to a second end face, opposite the first end face of the cartridge body. The cartridge body is composed of a core of a first material extending around the passage and sealing rings of a second material, extending around an axis of the passage at the first and second end faces. Surface portions of the sealing rings constituting surface portions of the first and second end faces. The first material is stronger and stiffer than the second material. | 01-13-2011 |
20110104026 | APPARATUS FOR EXTRACTING BIOCHEMICAL MATERIALS FROM BIOLOGICAL SAMPLES - Disclosed herein is a single-use extraction apparatus which is disposed of after use. The extraction apparatus includes a tube plate having a tube therein, and a column plate. The column plate is detachably coupled to the tube plate, and includes a column which corresponds to the tube of the tube plate. A filter is provided in the column and made of a material which adsorbs or desorbs biochemical materials included in biological samples. A hollow suction port is provided at a predetermined position of the column plate to connect to a vacuum pump. The apparatus is capable of extracting biochemical materials from biological samples by using vacuum pressure without centrifugal separation, thus realizing a simple, convenient and rapid extracting operation, and has a small size so that it rapidly reaches desired vacuum pressure and uniform vacuum pressure can act on the column. | 05-05-2011 |
20110104027 | CALIBRATION PROCEDURES AND DEVICES FOR INVESTIGATION BIOLOGICAL SYSTEMS - Use of calibrant in extraction phase is described for quantification of components of interest in samples in laboratory application as well as in on-site monitoring. This approach is particularly useful for in-vivo investigation of living system. | 05-05-2011 |
20110250105 | BLOOD SERUM OR BLOOD PLASMA SEPARATING MATERIAL AND BLOOD-COLLECTING TUBE USING SAME - The present invention relates to a serum or plasma separating material including a moisture curing component having a specific gravity of from 1.03 to 1.09, and a blood collection tube including the serum or plasma separating material. The present invention provides a serum or plasma separating material which is allowed to be present in a cured state between serum or plasma and a blood cell-containing component obtained after centrifugal separation when separating the serum or plasma component in a collection tube, exhibits a good storage stability capable of keeping the serum or the like and the cell-containing component in a separated state in the collection tube for a long period of time, is excellent in stability upon freezing or thawing and upon handling of a sample, and can be cured without need of irradiation with ultraviolet ray or the like, as well as a method of separating serum or plasma using the separating material. | 10-13-2011 |
20110262322 | Collection Tubes Apparatus, Systems and Methods - Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the separator substance within the lumen of the tube. The separator substance is formulated to have a density between an average density of a serum fraction of whole blood and a cell-containing fraction of whole blood, and to be flowable with whole blood. Upon centrifugation of a tube having blood, the separator substance forms a barrier between the whole blood fractions. The tube and barrier maintain stability of one or more analyte levels, including potassium and glucose, within 10% of their initial values before centrifugation for at least four days. | 10-27-2011 |
20110274594 | AB-REMOVER, AB-REMOVING APPARATUS, AND AB REMOVAL METHOD - An object is to provide a material capable of removing Aβ from a body fluid efficiently and use of the material, which are developed for the purpose of establishing a therapeutic or preventive method for Alzheimer's disease. Provided is an amyloid β protein remover, containing a carrier made of any one material selected from the group consisting of cellulose, silica, polyvinyl alcohol, and activated carbon, wherein the carrier does not have an alkyl chain on the surface thereof or has an alkyl chain having 1 to 18 carbon atoms on the surface thereof. | 11-10-2011 |
20110305608 | TRANSFER UNIT FOR ANALYSIS DEVICES - The invention relates to a transfer unit for analysis devices, containing a tube-shaped assembly which can be heated by an electric heater in a programmed manner, a tube ( | 12-15-2011 |
20120128550 | METHOD AND A DEVICE FOR TREATING MICROPARTICLES - Method for handling microparticles in such a manner, that at least two treatment steps are performed for microparticles in the same vessel without moving the particles to another vessel. There are organs in the device for changing the solution without having to move the microparticles to another vessel. | 05-24-2012 |
20120128551 | IONIC LIQUID MEDIATED SOL-GEL SORBENTS - Ionic liquid (IL)-mediated sol-gel hybrid organic-inorganic materials present enormous potential for effective use in analytical microextraction. One obstacle to materializing this prospect arises from high viscosity of ILs significantly slowing down sol-gel reactions. A method was developed which provides phosphonium-based, pyridinium-based, and imidazolium-based IL-mediated advanced sol-gel organic-inorganic hybrid materials for capillary microextraction. Scanning electron microscopy results demonstrate that ILs can serve as porogenic agents in sol-gel reactions. IL-mediated sol-gel coatings prepared with silanol-terminated polymers provided up to 28 times higher extractions compared to analogous sol-gel coatings prepared without any IL in the sol solution. This study shows that IL-generated porous morphology alone is not enough to provide effective extraction media: careful choice of the organic polymer and the precursor with close sol-gel reactivity must be made to ensure effective chemical bonding of the organic polymer to the created sol-gel material to be able to provide the desired sorbent characteristics. | 05-24-2012 |
20120148460 | Field flow fractionator with controllable cross flow along its length - A field flow fractionator to separate particles contained within an injected sample aliquot is described. As required, said fractionator may be used to capture, for subsequent removal, specific predefined classes of such particles. Based upon the cross flow or asymmetric flow field flow fractionators, the fractionator disclosed contains means to vary the applied transverse flows at a plurality of locations along the length of its separating channel. One embodiment utilizes a plurality of separated compartments, each lying below a distinct and corresponding membrane supporting permeable frit segment, are provided individual means to control the localized flow through the membrane section thereabove. A corresponding concentric compartment implementation achieves the same type of compartmentalized cross flow when integrated with a hollow fiber fractionator. | 06-14-2012 |
20120171086 | Separation Body for Three-Dimensional Chromatography - A separation body for three-dimensional chromatography, which provides at least one predefinable individual retention capacity in each spatial direction, for an analyte transported in a mobile phase in the respective direction. | 07-05-2012 |
20120288423 | MECHANICAL HOLDER FOR SURFACE ANALYSIS - A mechanical holder that provides for a confined sampling region for extraction and removal of chemical substances contained in a dried blood spot or other spot of sample is described herein. | 11-15-2012 |
20130045146 | PROTECTIVE BARRIER AGAINST CONTAMINATION FROM SAMPLE PREPARATION AND EXTRACTION DEVICES - A plastic device, such as a syringe barrel, tube, cartridge, filter disk, tubing, solvent reservoir, connector, valve, frit, or container, for transferring or storing solids and liquids used in sample preparation and extraction (SPE) methods, is provided with a barrier coating layer of Parylene over the surface of the plastic device, to prevent contamination of the solids and liquids being transferred or stored by the inventive plastic device from contaminants introduced from the plastic of the device. | 02-21-2013 |
20130121895 | CELL SEPARATION USING MICROCHANNEL HAVING PATTERNED POSTS - A micro flow device ( | 05-16-2013 |
20130129582 | METHOD FOR THE PLASMA-ENHANCED TREATMENT OF INTERNAL SURFACES OF A HOLLOW BODY, FLUID SEPARATOR, AND USE THEREOF - The present invention relates to the treatment of internal surfaces of a hollow body, on the inner surfaces of which areas having different surface properties, for example, having hydrophilic and hydrophobic properties, are produced. The invention further relates to fluid separators that are based on said hollow bodies and that have areas having different surface properties. Such fluid separators are used in medical technology and analysis, in particular biochemical analysis. | 05-23-2013 |
20130202500 | APPARATUS AND METHOD FOR SEPARATING COMPONENTS OF A SAMPLE LIQUID - Sample liquid is collected in a chamber downstream of a separating device. Adjoining the chamber are a plurality of channels which guide the sample liquid to one or more investigating regions. | 08-08-2013 |
20130209330 | EXHAUST GAS SAMPLING DEVICE - An exhaust gas sampling device is intended to heat or cool a temperature of sampled exhaust gas flowing through a sampling line to a desired temperature in accordance with various exhaust gas conditions and usage conditions of the sampling line irrespective of a temperature of the exhaust gas flowing through an exhaust pipe, and includes the sampling line for sampling the exhaust gas to be introduced into an analyzing instrument; a plurality of heating parts provided along the sampling line from an upstream side to a downstream side for heating the exhaust gas flowing through the sampling line; and a temperature control part for individually setting set temperatures of the plurality of heating parts using the temperature of the exhaust gas in the exhaust pipe and a target temperature of the exhaust gas in an outlet side of the heating part located in the most downstream as parameters. | 08-15-2013 |
20130309145 | METHOD AND A DEVICE FOR TREATING MICROPARTICLES - Method for handling microparticles in such a manner, that at least two treatment steps are performed for microparticles in the same vessel without moving the particles to another vessel. There are organs in the device for changing the solution without having to move the microparticles to another vessel. | 11-21-2013 |
20130330249 | SAMPLE PREPARATION BY SOLID PHASE EXTRACTION - A flow control assembly for use in preparation of samples for analysis by solid phase extraction includes a housing assembly having a first passage communicating with a needle bore and locating a solid phase sorbent, a second fluid port, and a valve for selective aspiration or delivery of fluid across a solid phase sorbent, or bypassing the solid phase sorbent. Independent flow paths are provided for a sample via the needle, and of the elution solvent via a separate port. The valve includes relatively slideable first and second members, the second member including an elongate shank that is relatively reciprocably slideable for effecting selective aspiration or delivery of fluid between first and second relative positions. A third fluid port may be provided communicating with the elongate second passage for selective fluid communication with a port in a shank when the shank is at the second relative position. | 12-12-2013 |
20130330250 | DEVICE - A device includes: a tube having a first portion and a second portion; and a plunger insertable from the first portion side of the tube and having a tubular portion that can fit an inner surface of the first portion and a rod-like portion that can fit an inner surface of the second portion and is supported by the tubular portion, wherein when the tubular portion fits the inner surface of the first portion, a first state where the inner surface of the second portion and the rod-like portion are spaced apart from each other and a second state where the inner surface of the second portion and the rod-like portion fit together are formed, and in the first state, a communication path communicating the inside of the second portion with the inside of the tubular portion is formed, while in the second state, the communication path is blocked. | 12-12-2013 |
20130330251 | CARRIER ENCLOSING TIP, CARRIER TREATING APPARATUS AND METHOD OF CARRIER TREATMENT - The invention relates to a carrier enclosing tip, a carrier treating apparatus, and a method of carrier treatment. An object is to perform separation/purification more efficiently and rapidly as compared with treatments using conventional liquid chromatography or filters. There is provided a carrier enclosing tip comprising: a tip-like container having a fitting opening which is fittable to a nozzle for use in gas suction and discharge, or a member to be fitted to a nozzle, and a port through which fluid inflow and outflow can be effected by the gas suction and discharge; and a carrier which is enclosed in the tip-like container, and is capable of adsorbing a biosubstance in the fluid or is capable of reacting with or binding to the biosubstance. | 12-12-2013 |
20140112840 | Device For And Method Of Extracting A Fraction From A Biological Sample - A device is provided for facilitating the isolation of a fraction from a biological sample. The biological sample includes non-desired material and a fraction-bound solid phase substrate. The device includes an input zone for receiving the biological sample therein and a second zone interconnected to the input zone by a channel. A force attracts the fraction-bound solid phase substrate and is movable along a path between a first position adjacent the input zone, a second position adjacent the channel, and a third position adjacent the second zone. The force has a generally arcuate edge for concentrating the fraction-bound solid phase substrate along the path. The force urges the fraction-bound solid phase substrate from the input zone, through the channel and into the second zone as the force moves from the first position to the third position. | 04-24-2014 |
20140134078 | METHODS AND APPARATUSES FOR NUCLEIC ACID PURIFICATION - An apparatus for purifying nucleic acid can include a disposable cartridge having a layered configuration, and a disposable syringe for coupling to the disposable cartridge such that a fluid can be delivered to or withdrawn fluid from the disposable cartridge using the syringe. At least one layer of the disposable cartridge can include a cut-out for forming a functional unit of the disposable cartridge, and at least one layer of the disposable cartridge can be joined to an adjacent layer of the disposable cartridge by an adhesive material layer. The functional unit can include a fluid channel between an access port on the first surface of the disposable cartridge and the fluid pouch. The apparatus can include a disposable silica-containing material for binding with the nucleic acid. The apparatus can include a heating element and a temperature sensor for heating the disposable silica-containing material. | 05-15-2014 |
20140186236 | METHOD FOR PURIFICATION OF NUCLEIC ACIDS, PARTICULARLY FROM FIXED TISSUE - The invention relates to a method for purification of nucleic acids, to a kit for performing the method according to the invention and to a new application of magnetic particles for purification of a biological sample. The method according to the invention comprises the following steps: a) accommodating of the sample in a first sample vessel in an aqueous solution and lysing of the sample under non-chaotropic conditions; suspending of first magnetic particles in the solution and inserting of the first sample vessel in a sample vessel holder, wherein the sample vessel is inserted in the annular interior space of a ring magnet associated with the sample vessel holder; separating of the solution from the magnetic particles; and isolating of the nucleic acids from the solution. | 07-03-2014 |
20140255271 | Device for Rapid Urine Concentration - The present invention provides a device for the concentration of one or more target analytes contained in a urine sample. The device comprises a tube comprising an upper portion defining an opening for receiving the urine sample and a lower tapered portion terminating in a collection reservoir. The tube contains a predetermined amount of a particulate binding agent which specifically binds the one or more target analytes and of a predetermined amount of a binding buffer. The device comprises means for sealing the opening of the tube. The present invention further provides methods and kits for concentrating one or more target analytes in a urine sample. | 09-11-2014 |
20140255272 | METHOD AND SYSTEM FOR SELECTIVE ISOLATION OF TARGET BIOLOGICAL MOLECULES IN A GENERAL PURPOSE SYSTEM - Embodiments of the present techniques provide systems and methods for isolating particular classes of biological molecules, for example, proteins or nucleic acids, from mixtures of biological components. The methods use solutions that react with the biological molecules to enhance their adsorption by substrates, allowing contaminants to be washed away from the targeted molecules. Embodiments include automated systems that can be used to implement the technique with no or minimal intervention. Other embodiments include separation column technologies that may be used in the techniques. | 09-11-2014 |
20140308179 | Biological Fluid Separation Device and Biological Fluid Separation and Testing System - A biological fluid separation device that is adapted to receive a multi-component blood sample is disclosed. After collecting the blood sample, the biological fluid separation device is able to separate a plasma portion from a cellular portion. After separation, the biological fluid separation device is able to transfer the plasma portion of the blood sample to a point-of-care testing device. The biological fluid separation device of the present disclosure also provides a closed separation and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with a sample stabilizer. The biological fluid separation device is engageable with a blood testing device for closed transfer of a portion of the plasma portion from the biological fluid separation device to the blood testing device. The blood testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results. | 10-16-2014 |
20150010442 | INTRODUCING AN ANALYTE INTO A CHEMICAL ANALYZER - A chemical pre-concentrator includes a conduit defining a flow path between two ends and having a heating element disposed within the conduit, such that the heating element has at least one sorbent material deposited directly on at least a portion of a conductive surface of the heating element. Some such heating elements are in the form of electrically conductive strips defining both a plurality of apertures through the strip and a series of undulations spaced along the flow path. | 01-08-2015 |
20150093304 | INTEGRATED MODULAR UNIT INCLUDING AN ANALYTE CONCENTRATOR MICROREACTOR DEVICE CONNECTED TO A CARTRIDGE-CASSETTE - The integrated modular and interchangeable unit of the present invention comprises an analyte concentrator-microreactor (ACM) device having four entrance-exit ports identified as connection areas to a transport capillary for sample and buffer introduction, and to a separation capillary of a cartridge-cassette filled with an appropriate separation fluid for optimal separation of the analytes of interest. Affinity ligand groups are immobilized to microstructures contained within the main inner cavity or channel of the device or directly to the wall of the main inner channel for capturing one or more analytes. The inlet and outlet ends of the transport capillary are connected through a parallel design option to the analyte concentrator-microreactor (ACM) device to facilitate the path of sample and buffers through the inner cavity or channel of the analyte concentrator-microreactor (ACM) device. | 04-02-2015 |
20150098874 | SEGMENTABLE CONTAINER AND METHOD OF SEGMENTING SUBSTANCE CONTAINED IN CONTAINER - Provided are a simple, quick, and low-processing cost method capable of reliably separating part of an accommodated substance accommodated in a vessel only by simple mechanical operation while maintaining a hermetically-sealed state without any contact with an outside atmosphere, as well as a vessel with which the method may be used. A separable vessel comprises a first vessel portion, a second vessel portion which is contiguous with the first vessel portion, a fracture-inducing portion formed between the first vessel portion and the second vessel portion, and a self-fusing material provided on an outer surface so as to cover the fracture-inducing portion; and may contain an accommodated substance therein. | 04-09-2015 |
20150104358 | NUCLEIC ACID EXTRACTION DEVICE, NUCLEIC ACID EXTRACTION KIT, AND NUCLEIC ACID EXTRACTION APPARATUS - A nucleic acid extraction device has a tube in which a first plug formed of an oil, a second plug formed of a washing liquid which does not mix with an oil, a third plug formed of an oil, a fourth plug formed of an eluate which does not mix with an oil, and a fifth plug formed of an oil are arranged in this order, and the tube is subjected to an antistatic treatment. | 04-16-2015 |
20150300998 | MICROCOLUMN FOR USE IN GAS CHROMATOGRAPHY - A microcolumn for use in gas chromatography comprises a self-supporting polymer body that functions as a stationary phase and a structural support. The polymer body comprises an enclosed channel having a length L, height h and width w extending therethrough and one or more channel walls surrounding the enclosed channel. The one or more channel walls are integrally formed with the polymer body. The polymer body and the one or more channel walls may comprise a phase-separated polymer composition. | 10-22-2015 |
20150321191 | INTEGRATION OF EX SITU FABRICATED POROUS POLYMER MONOLITHS INTO FLUIDIC CHIPS - Bare porous polymer monoliths, fluidic chips, methods of incorporating bare porous polymer monoliths into fluidic chips, and methods for functionalizing bare porous polymer monoliths are described. Bare porous polymer monoliths may be fabricated ex situ in a mold. The bare porous polymer monoliths may also be functionalized ex situ. Incorporating the bare preformed porous polymer monoliths into the fluidic chips may include inserting the monoliths into channels of channel substrates of the fluidic chips. Incorporating the bare preformed porous polymer monoliths into the fluidic chips may include bonding a capping layer to the channel substrate. The bare porous polymer monoliths may be mechanically anchored to channel walls and to the capping layer. The bare porous polymer monoliths may be functionalized by ex situ immobilization of capture probes on the monoliths. The monoliths may be functionalized by direct attachment of chitosan. | 11-12-2015 |
20150367253 | PHOTOLUMINESCENT THIN-LAYER CHROMATOGRAPHY PLATE AND METHODS FOR MAKING SAME - In an embodiment, a method for manufacturing a chromatography apparatus such as a thin layer chromatography (“TLC”) plate is disclosed. The method includes forming a layer of elongated nanostructures (e.g., carbon nanotubes), and at least partially coating the oxidized elongated nanostructures with a coating. The coating includes a stationary phase and/or precursor of a stationary phase and at least one photoluminescent material for use in chromatography. Embodiments for TLC plates and related methods are also disclosed. | 12-24-2015 |
20160001284 | Fluidic Interfacing System and Assembly - A fluidic assay system assembly comprising: (a) A disposable fluidic cartridge ( | 01-07-2016 |
20160090587 | NUCLEIC ACID PURIFICATION DEVICE - In a nucleic acid purification device, a washing container in which a washing solution are sealed by in a first channel and an elution container in which an eluate are sealed by in a second channel are bonded to each other to form a channel for moving a nucleic acid, the washing container includes an outer peripheral wall which is arranged by being spaced apart from the first channel and accommodates a connection portion of the first channel and the second channel, and the elution container includes a first flange which has a gap in a portion between the outer peripheral wall and an inner wall and is in contact with the inner wall and a second flange which has a gap in a portion between the outer peripheral wall and the inner wall and is in contact with the inner wall. | 03-31-2016 |
20160090619 | NUCLEIC ACID PURIFICATION DEVICE - In a nucleic acid purification device, a washing container and an elution container are bonded to each other to form a channel for moving a nucleic acid, the washing container includes an outer peripheral wall which accommodates a connection portion of the first channel and a second channel, the elution container includes a plurality of flanges in the periphery of the second channel in contact with an inner wall of the outer peripheral wall, the plurality of flanges are arranged in a portion which is to be inserted into the inside of the outer peripheral wall of the elution container, and one space which is partitioned by two flanges adjacent to each other among the plurality of flanges and the outer peripheral wall communicates with another space adjacent to the one space in a state of being divided by one of the two flanges adjacent to each other. | 03-31-2016 |
20160116386 | MAGNETIC SEPARATION RACK ASSEMBLY - The present invention provides a magnetic separation assembly. The assembly includes a base having at least one opening. The assembly also includes a holder positioned securely inside the at least one opening of the base. The holder includes a magnet. The assembly also includes a retainer securely inserted into the holder. | 04-28-2016 |
20160161378 | APPARATUS FOR SEPARATING MICRO-PARTICLES - An apparatus for separating micro-particles includes a channel through which a fluid flows, and a separating part protruding into the channel and including a slanted element inclined toward a length direction of the channel and a vertical element perpendicular to the length direction of the channel. | 06-09-2016 |
20160202156 | SAMPLE PLATE FOR SLIDING MAGNETIC PARTICLE SEPARATION | 07-14-2016 |
20160202157 | ADAPTER FOR SLIDING MAGNETIC PARTICLE SEPARATION | 07-14-2016 |
20170234783 | BIOLOGICAL SUBSTANCE EXTRACTION DEVICE AND BIOLOGICAL SUBSTANCE EXTRACTION APPARATUS | 08-17-2017 |
20190145875 | A METHOD FOR PREPARING A SUBSTRATE BY APPLYING A SAMPLE TO BE ANALYSED | 05-16-2019 |