| Class / Patent application number | Description | Number of patent applications / Date published |
|---|
| 800285000 | The polynucleotide encodes an inhibitory RNA molecule | 41 |
| 20130125260 | BIOASSAY FOR GENE SILENCING CONSTRUCTS - The invention provides constructs and methods of screening for constructs useful in conferring resistance in plants to pests by gene silencing. The invention also provides pest-resistant plants transformed with the present constructs. One screening method of the invention comprises the steps of: selecting at least one pest target nucleotide sequence, producing a plurality of dsRNA test agents that target the pest target nucleotide sequence, testing and scoring the plurality of dsRNA test agents for toxicity to the pest, and producing a silencing construct based on a superior-scoring test agent. | 05-16-2013 |
| 20130125259 | RNA INTERFERENCE MEDIATING SMALL RNA MOLECULES - Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a | 05-16-2013 |
| 20100088785 | COMPOSITIONS AND METHODS FOR MODULATING EXPRESSION OF GENE PRODUCTS - Compositions and methods for modulating expression of gene products are provided. Compositions comprise suppression cassettes that comprise a convergent promoter pair operably linked to a silencing element that, upon expression, is capable of decreasing the expression of one or more target polynucleotides of interest. Compositions of the invention also include transformed plants, plant cells, plant tissues, and plant seeds. Methods of transformation and regeneration of plants comprising the novel constructs are provided. The methods find use in regulating gene expression, particularly genes associated with agronomic traits of interest. Further provided are promoter sequences, cells, plants, and vectors comprising these promoter sequences and methods of their use. | 04-08-2010 |
| 20090183280 | Transgenic Plants Modified for Reduced Cadmium Transport, Derivative Products, and Related Methods - Various embodiments are directed to transgenic plants, including transgenic tobacco plants and derivative seeds, genetically modified to impede the transport of Cadmium (Cd) from the root system to aerial portions of transgenic plants by reducing the expression levels of HMA-related transporters. Various embodiments are directed to transgenic tobacco plants genetically modified to stably express a RNAi construct encoding RNAi polynucleotides that enable the degradation of endogenous NtHMA RNA variants. Reduced expression of NtHMA transporters in transgenic plants results in substantially reduced content of Cadmium (Cd) in the leaf lamina. Various consumable products that are substantially free or substantially reduced in Cd content can be produced by incorporating leaves derived from transgenic tobacco plants modified to reduce the expression of NtHMA transporters. | 07-16-2009 |
| 20090205081 | Nucleic acid molecules and other molecules associated with plants - Expressed Sequence Tags (ESTs) isolated from lily are disclosed. The ESTs provide a unique molecular tool for the targeting and isolation of novel genes for plant protection and improvement. The disclosed ESTs have utility in the development of new strategies for understanding critical plant developmental and metabolic pathways. The disclosed ESTs have particular utility in isolating genes and promoters, identifying and mapping the genes involved in developmental and metabolic pathways, and determining gene function. Sequence homology analyses using the ESTs provided in the present invention, will result in more efficient gene screening for desirable agronomic traits. An expanding database of these select pieces of the plant genomics puzzle will quickly expand the knowledge necessary for subsequent functional validation, a key limitation in current plant biotechnology efforts. | 08-13-2009 |
| 20120144527 | Gene Silencing - The invention provides methods and compositions useful in target sequence suppression and target sequence validation. The invention provides polynucleotide constructs useful for gene silencing, as well as cells, plants and seeds comprising the polynucleotides. The invention also provides a method for using microRNA to silence a target sequence. | 06-07-2012 |
| 20080229456 | Recombinant DNA constructs and methods for controlling gene expression - The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy. | 09-18-2008 |
| 20100313304 | Engineering single-gene-controlled staygreen potential into plants - The enzymes of the ACC synthase family are used in producing ethylene. Nucleotide and polypeptide sequences of ACC synthases are provided along with knockout plant cells having inhibition in expression and/or activity in an ACC synthase and knockout plants displaying a staygreen phenotype, a male sterility phenotype, or an inhibition in ethylene production. Methods for modulating staygreen potential in plants, methods for modulating sterility in plants, and methods for inhibiting ethylene production in plants are also provided. | 12-09-2010 |
| 20110030099 | PLANTS AND MODULATORS FOR IMPROVED DROUGHT TOLERANCE - Methods of conferring increased drought tolerance to a plant by reducing or inhibiting ammonia accumulation, and plants produced thereby. | 02-03-2011 |
| 20100071092 | METHODS AND GENETIC CONSTRUCTS FOR MODIFICATION OF LIGNIN COMPOSITION OF CORN COBS - Expression cassettes causing specific regulatory control of transgene expression in plants, wherein the expression cassettes include regulatory sequences from the MADS gene family for expression of recombinant gene products in the reproductive tissue of plants for the purpose of generating maize plants with altered lignin content of the cobs. | 03-18-2010 |
| 20110154538 | Infectious Plant Viral Vector and An Artificial Bipartite Plant Viral Vector An Infectious Plant Viral Vector and An Artificial Bipartite Plant Viral Vector - We have developed a versatile plant viral vector system based on Alternanthera mosaic virus (AltMV), suitable for infection by agroinfiltration or in vivo T7 transcripts from the same clone; agroinfection is enhanced by coinfiltration of a T7 RNA polymerase construct. Variants adapted for efficient protein expression, or for virus-induced gene silencing (VIGS), are based on a specific amino acid substitution (L88P) in the triple gene block 1 (TGB1) protein affecting RNA silencing suppression. A bipartite delivery system developed for AltMV delivers replicase (RdRp) functions separately from movement and encapsidation (TGB and coat protein, CP) functions by agroinfiltration, resulting in precise recombination of RdRp and TGB-CP constructs in planta. The bipartite delivery system has potential for high throughput protein expression or VIGS with the appropriate TGB1 variant, for hosts including | 06-23-2011 |
| 20110083232 | MAIZE MICRORNA SEQUENCES - Methods and compositions useful in target sequence suppression and target sequence validation are described. Polynucleotide constructs useful for gene silencing, as well as cells, plants and seeds comprising the polynucleotides and a method for using microRNAs to silence a target sequence are also described. | 04-07-2011 |
| 20110307974 | PLANT GROWTH PROMOTING PROTEIN COMPLEX - The present invention relates to a plant growth promoting protein complex. More specifically, the invention relates to the use of specific proteins from the Anaphase Promoting Complex/Cyclosome for increasing shoot growth rates and/or enhancing cell division rates. | 12-15-2011 |
| 20090172838 | Compositions and methods for efficient gene silencing in plants - This invention relates to methods for knock-down of a target gene in plants, particularly efficient and specific methods for knock-down of a target gene in plants. This invention also relates to methods for silencing endogenous plant genes or plant pathogen genes. It further relates to nucleic acid constructs (DNA, RNA) which comprise a nucleic acid sequence that corresponds to a target gene or fragment thereof flanked by two complementary sites to an smRNA, e.g., a miRNA (one complementary site is on either side of the nucleic acid sequence), resulting in, for example the configuration: complementary site—nucleic acid sequence that corresponds to a target gene—complementary site. | 07-02-2009 |
| 20120005781 | NUCLEOTIDE SEQUENCES AND CORRESPONDING POLYPEPTIDES CONFERRING MODULATED PLANT GROWTH RATE AND BIOMASS IN PLANTS - The present invention relates to isolated nucleic acid molecules and their corresponding encoded polypeptides able confer the trait of modulated plant size, vegetative growth, organ number, plant architecture, growth rate, seedling vigor, growth rate, fruit and seed yield, tillering and/or biomass in plants. The present invention further relates to the use of these nucleic acid molecules and polypeptides in making transgenic plants, plant cells, plant materials or seeds of a plant having plant size, vegetative growth, organ number, plant architecture, growth rate, seedling vigor and/or biomass that are altered with respect to wild type plants grown under similar conditions | 01-05-2012 |
| 20110004958 | COMPOSITIONS FOR SILENCING THE EXPRESSION OF GIBBERELLIN 2-OXIDASE AND USES THEREOF - The present invention provides an isolated nucleic acid sequence encoding gibberellin 2-oxidase enzyme (GA 2-oxidase) of | 01-06-2011 |
| 20120240290 | Methods and Compositions for Modulating Flowering and Maturity in Plants - The present invention provides compositions and methods for modulating flowering time in plants. Maize RAP2.7 nucleotide sequences are disclosed which upon overexpression cause later flowering and when inhibited cause earlier flowering. Also disclosed is a DNA sequence which acts as a regulator/enhancer of RAP2.7, termed VGT1. This sequence does not code for any known protein, but acts as either a RNAi element or a regulatory DNA or RNA element that either directly regulates expression of flowering genes such as Rap2.7 or specifically targets expression of other genes which control flowering genes such as Rap2.7. This element this can be used as a sequence—based marker to identify inbred and hybrids which have altered maturity. Methods for expressing these nucleotide sequences in a plant for modifying maturity and flowering in plants are provided as well as expression constructs, vectors, transformed cells and plants. | 09-20-2012 |
| 20120272406 | METHODS OF MODIFYING LIGNIN BIOSYNTHESIS AND IMPROVING DIGESTIBILITY - The present invention relates to methods for increasing digestibility and/or crude protein of a plant by modifying lignin biosynthesis of the plant. The methods involve the manipulation of the expression level of genes in the lignin biosynthesis pathway by directly reducing the expression of genes using miRNA or using regulation of transcription factors. Expression cassettes for achieving such gene expression manipulation and transgenic plant cells and plants comprising the constructs and cassettes are also provided. Transcription regulating nucleotide sequences for use in the expression cassettes have also been developed as well as methods of using these sequences and cassettes. | 10-25-2012 |
| 20120102598 | MIR164 Gene That Controls Plant Root System Development and Fertility and Use Thereof - A rice microRNA, miR164 gene, that controls plant root system development and fertility, is obtained through gene isolation, cloning and function verification. Uses of a nucleic acid fragment comprising miR164, which fragment may confer a transformed plant with the ability to increase root number and to alter fertility, wherein the said nucleic acid fragment is selected from one of the following nucleotide sequences: 1) a DNA sequence as shown in SEQ ID NO: 1; 2) a RNA sequence as shown in SEQ ID NO:2; or 3) the conserved sequence of miR164 having the same function as 1) or 2). The nucleotide sequence containing the precursor of miR164 is ligated with an exogenous promoter and introduced into rice to obtain transgenic rice plants which has large root systems but became infertile. The fertility can be restored by external application of phytohormones. | 04-26-2012 |
| 800286000 | The RNA is antisense | 22 |
| 20120180162 | GENERATION OF HIGH POLYHYDROXYBUTRATE PRODUCING OILSEEDS - Transgenic plants, plant material, plant cells, and genetic constructs for synthesis of biopolymers, for example polyhydroxyalkanoates (“PHA”) are provided. In one embodiment, the transgenic plants synthesize polyhydroxybutyrate (“PHB”). In one embodiment the transgenic plant encodes siRNA for one or more of the genes encoding enzymes for producing PHA. In a more preferred embodiment, the siRNA expression is under the control of an inducible regulatory element. In another embodiment, the transgenic plant contains transgenes that encode expression enzymes that will degrade the polymer. In a preferred embodiment, the expression of these enzymes is under the control of a germination specific, inducible, or minimal promoter. In another embodiment, the transgenic plant contains transgenes encoding enzymes that increase carbon flow for polymer synthesis. In a preferred embodiment, these transgenes encode enzymes that increase carbon flow in the Calvin Cycle. | 07-12-2012 |
| 20130036515 | Banana MADS-Box Genes for Banana Ripening Control - The ripening of banana fruit may be delayed or suppressed by use of a DNA construct comprising a silencing nucleic acid sequence which is effective for significantly reducing or eliminating the expression of MaMADS1 or MaMADS2 or both in the fruit. The silencing nucleic acid sequence in this construct is operatively linked to a promoter effective for expression in the fruit. The fruit of plants transformed with this construct exhibit significantly delayed ripening in comparison to fruit from non-transformed plants. | 02-07-2013 |
| 20090070899 | Phenylpropanoid related regulatory protein-regulatory region associations - Materials and Methods for identifying lignin regulatory region-regulatory protein associations are disclosed. Materials and methods for modulating lignin accumulation are also disclosed. | 03-12-2009 |
| 20110173721 | REDUCED RISK TOBACCO PRODUCTS AND METHODS OF MAKING SAME - Embodiments provided herein concern tobacco and tobacco products having a reduced amount of a harmful compound. More specifically, several embodiments concern approaches to modify the expression of a gene that is involved in the production of a harmful compound in tobacco, tobacco products made using these approaches and methods of determining whether the removal of said compounds using said approaches yields a tobacco and/or a tobacco product that has a reduced potential to contribute to a tobacco-related disease. | 07-14-2011 |
| 20110271402 | INCREASE IN YIELD BY REDUCING GENE EXPRESSION - The present invention relates to a process for the increase in yield in a plant organism by reducing gene expression. The invention furthermore relates to nucleic acid molecules, polypeptides, nucleic acid constructs, vectors, antisense molecules, antibodies, host cells, plant tissue, propagation material, harvested material and plants. | 11-03-2011 |
| 20090070898 | Plant microRNAs and methods of use thereof - This invention discloses novel microRNAs and their precursors, and recombinant DNA constructs including such novel miRNAs, miRNA precursors, miRNA promoters, and miRNA recognition sites corresponding to the miRNAs. Included are novel miRNA and miRNA precursors that exhibit nutrient-responsive expression. Also disclosed are miRNA decoy sequences. Further provided are non-natural transgenic plant cells, plants, and seeds containing in their genome a recombinant DNA construct of this invention and methods of controlling gene expression using recombinant DNA constructs of this invention. | 03-12-2009 |
| 20080216193 | MATERIALS AND METHODS FOR THE MODULATION OF CYCLIN-DEPENDENT KINASE INHIBITOR-LIKE POLYPEPTIDES IN MAIZE - Isolated or purified nucleic acid molecules encoding polypeptides having cyclin-dependent kinase (CDK) inhibitor-like activity; vectors; host cells; polypeptides having CDK inhibitor-like activity; nucleic acid constructs for suppression of CDK inhibitor-like activity; methods of suppressing and up-regulating the expression of one or more CDK inhibitor-like genes in a maize cell, tissue, organ, or plant; a maize cell, tissue, organ, or plant in which the expression of a CDK inhibitor-like gene has been suppressed or up-regulated in accordance with such methods; and a seed (and the oil and meal thereof) obtained from a plant in which the expression of one or more CDK inhibitor-like genes has been suppressed or up-regulated. | 09-04-2008 |
| 20120096590 | METHODS FOR INCREASING PLANT CELL PROLIFERATION BY FUNCTIONALLY INHIBITING A PLANT CYCLIN INHIBITOR GENE - The present invention provides methods for modulating the growth and/or yield of plants. In particular the methods comprise the use of agents which functionally inhibit the expression of plant D-like cyclin inhibitors including isolated polynucleotide sequences which interact with DNA or RNA encoding proteins capable of binding plant D-like cyclins. Further, the present invention provides recombinant polynucleotide sequences, vectors and host cells which encode proteins capable of binding to and inactivating the activity of plant D-like cyclin/cyclin dependent kinase complexes preventing plant cells from exiting the cell cycle. Methods for determining and agents which are inhibitors of the BRO cyclin dependent kinase inhibitor proteins which are capable of modulating plant cell cycle progression are also provided. Methods for the production of transgenic plant cells and plants with increased growth rates and yields when compared to wild-type plants are also provided. | 04-19-2012 |
| 20110004959 | DOWN-REGULATION AND SILENCING OF ALLERGEN GENES IN TRANSGENIC PEANUT SEEDS - An allergen-free transgenic peanut seed is produced by recombinant methods. Peanut plants are transformed with multiple copies of each of the allergen genes, or fragments thereof, to suppress gene expression and allergen protein production. Alternatively, peanut plants are transformed with peanut allergen antisense genes introduced into the peanut genome as antisense fragments, sense fragments, or combinations of both antisense and sense fragments. Peanut transgenes are under the control of the 35S promoter, or the promoter of the Ara h2 gene to produce antisense RNAs, sense RNAs, and double-stranded RNAs for suppressing allergen protein production in peanut plants. A full length genomic clone for allergen Ara h2 is isolated and sequenced. The ORF is 622 nucleotides long. The predicted encoded protein is 207 amino acids long and includes a putative transit peptide of 21 residues. One polyadenilation signal is identified at position 951. Six additional stop codons are observed. A promoter region was revealed containing a putative TATA box located at position −72. Homologous regions were identified between Ara h2, h6, and h7, and between Ara h3 and h4, and between Ara h1P41B and Ara h1P17. The homologous regions will be used for the screening of peanut genomic library to isolate all peanut allergen genes and for down-regulation and silencing of multiple peanut allergen genes. | 01-06-2011 |
| 20110214206 | Nucleic acid molecules and other molecules associated with plants - Polynucleotides useful for improvement of plants are provided. In particular, polynucleotide sequences are provided from plant sources. Polypeptides encoded by the polynucleotide sequences are also provided. The disclosed polynucleotides and polypeptides find use in production of transgenic plants to produce plants having improved properties. | 09-01-2011 |
| 20090265811 | MAIZE PLANTS WITH REDUCED GENE SILENCING - Maize plants with reduced gene silencing are disclosed. | 10-22-2009 |
| 20110258739 | POLYNUCLEOTIDE SEQUENCE OF FRUIT SOFTENING ASSOCIATED B-D-N- ACETYLHEXOSAMINIDASE AND ITS USES FOR ENHANCING FRUIT SHELF LIFE - The present invention provides isolated polynucleotide sequences encoding β-D-N-acetylhexosaminidase. The present invention further provides DNA construct comprising the polynucleotide sequence coding for β-D-N-acetylhexosaminidase in sense or anti-sense orientation, RNAi construct, recombinant vector comprising the construct and host cells comprising the recombinant vector disclosed in the present invention. The present invention further provides transgenic plant, plant cell, transgenic progeny and seeds expressing the polynucleotide with reduced β-D-N-acetylhexosaminidase protein accumulation, having enhanced fruit shelf life | 10-20-2011 |
| 20110126321 | RECOMBINANT DNA FOR GENE SUPPRESSION - Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5′ to 3′ order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element. | 05-26-2011 |
| 20090210967 | Glutamate Receptors as Regulators of Carbon Transport, Mobilization, Distribution, Reallocation, and Partitioning in Higher Plants - This invention relates to compounds for improving plant growth and characteristics, improved modified plants, processes for obtaining the same, and improved methods of obtaining plant products, and specifically those concerning AtGLR1.1. | 08-20-2009 |
| 20110154539 | CONTROL OF FRUIT DEHISCENCE IN PLANTS BY INDEHISCENT1 GENES - The present application provides methods and compositions that modulate fruit dehiscence in plants. | 06-23-2011 |
| 20110314571 | METHOD TO TRIGGER RNA INTERFERENCE - A method to generate siRNAs in vivo is described, as are constructs and compositions useful in the method. The method does not depend on the use of DNA or synthetic constructs that contain inverted duplications or dual promoters so as to form perfect or largely double-stranded RNA. Rather, the method depends on constructs that yield single-stranded RNA transcripts, and exploits endogenous or in vivo-produced miRNAs or siRNAs to initiate production of siRNAs. The miRNAs or siRNAs guide cleavage of the transcript and set the register for production of siRNAs (usually 21 nucleotides in length) encoded adjacent to the initiation cleavage site within the construct. The method results in specific formation of siRNAs of predictable size and register (phase) relative to the initiation cleavage site. The method can be used to produce specific siRNAs in vivo for inactivation or suppression of one or more target genes or other entities, such as pathogens. | 12-22-2011 |
| 20120073018 | JATROPHA CURCAS CURCIN GENES, TISSUE-SPECIFIC PROMOTERS AND GENERATION OF CURCIN-DEFICIENT TRANSGENIC JATROPHA PLANTS - The present invention relates to the isolation of | 03-22-2012 |
| 20120124701 | PROMOTER, PROMOTER CONTROL ELEMENTS, AND COMBINATIONS, AND USE THEREOF - The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels in plants, and plants containing such promoters or promoter control elements. | 05-17-2012 |
| 20120167253 | POLYNUCLEOTIDE COMPRISING SEQUENCES OF WHEAT GLIADINS AND USE THEREOF FOR SILENCING BY RNAI - The present invention relates to the specific silencing of the α (alpha), β (beta), γ (gamma) and ω (omega)-gliadins of hard wheat for flour by RNA interference (RNAi) through employment of a polynucleotide which is transcribed into an hpRNA (hairpin RNA). Furthermore the present invention additionally relates to a vector, cell, plant or seed comprising the polynucleotide, the expression whereof is specifically directed in particular tissues of wheat seeds through gene expression-regulating sequences such as, for example, the promoter of a gene of γ-gliadins or the promoter of the gene encoding for a D-hordein. | 06-28-2012 |
| 20130019343 | Expression Cassettes for Seed-Preferential Expression in Plants - The present invention relates to expression cassettes comprising transcription regulating nucleotide sequences with seed-preferential or seed-specific expression profiles in plants obtainable from the | 01-17-2013 |
| 20120233727 | CLONING OF CYTOCHROME P450 GENES FROM NICOTIANA - The present invention relates to p450 enzymes and nucleic acid sequences encoding p450 enzymes in | 09-13-2012 |
| 20110231955 | EFFICIENT GENE SILENCING IN PLANTS USING SHORT dsRNA SEQUENCES - Methods and means are provided to increase the efficiency of gene silencing when using dsRNA sequences which have a stem length shorter than about 200 base pairs by providing chimeric genes encoding such dsRNA sequences with a promoter recognized by DNA dependent RNA polymerase III comprising all cis-acting promoter elements which interact with DNA dependent RNA polymerase III. | 09-22-2011 |
