Class / Patent application number | Description | Number of patent applications / Date published |
623230600 | Bone surface coating | 26 |
20080281429 | Applications of Diffusion Hardening Techniques - A device, for example a medical implant, and a method of making the same, the device having a metal or metal alloy substrate, for example CoCr, and a diffusion hardened metallic surface, for example a plasma carburized surface, contacting a non-diffusion hardened surface or a diffusion hardened surface having a diffusion hardening species different from that of the opposing surface. | 11-13-2008 |
20090005880 | Method for Preparing Endosseous Implants Anatase Titanium Dioxide Coating - The method includes the following steps: formulation of liquid, non-gelled and stable precursor by solvolysis of Ti(IV) compounds; precursor deposition on endosseous implant surface; thermal treatment to achieve film densification, in the presence of oxygen, of a complex formed by the above mentioned endosseous implant and precursor, to obtain on the implant surface a thin film of nanocrystalline titanium dioxide with good mechanical and chemical stability. The complex above, under a persistent W irradiation modify its surface status conferring a sensible increasing of wettability chemical and biological decontamination. | 01-01-2009 |
20090187253 | METHOD OF MAKING A COATED MEDICAL BONE IMPLANT AND A MEDICAL BONE IMPLANT MADE THEREOF - The present invention relates to a method of making a coated medical bone implant comprising the step of providing a substrate and then onto said substrate depositing a bioactive crystalline TiO | 07-23-2009 |
20090270997 | USE OF NANOMATERIALS BASED ON TITANIUM DIOXIDE AND ZIRCONIUM DIOZIDE AS COATINGS FOR OSTEOINTEGRATED BIOMEDICAL PROSTHESES, AND OSTEOINTEGRATED BIOMEDICAL PROSTHESES PREPARED THEREWITH - The present invention proposes novel materials and methods, for preparation of coatings based on titanium dioxide for osteointegrated biomedical prostheses. The coatings are realized with nanomaterials having antibacterial properties, and have the purpose of: promoting osteointegration of the implants, and, at the same time, reducing reaction attributable to inflammatory processes which derive from infections which may develop in the neighborhood of the implants. In particular, the present invention relates to an endo-osseous implant comprised of biocompatible metallic materials; characterized in that said implant comprises a coating comprised of nanocrystalline material comprising nanoparticles of formula (I) AO | 10-29-2009 |
20100016985 | PROCESSING OF BIOCOMPATIBLE COATING ON POLYMERIC IMPLANTS - The present invention provides polymeric substrates comprising a biocompatible coating and methods of preparation thereof. In particular, the coating may be a ceramic material, especially a calcium phosphate material, which may be functionally graded. The invention provides the ability to apply high quality coatings to polymeric substrates without damaging the substrate (e.g., melting the polymeric material). The functionally graded coating can provide crystalline calcium phosphate near the coating interface with the substrate and provide amorphous calcium phosphate at the outer surface of the coating. | 01-21-2010 |
20100036502 | MEDICAL DEVICE FOR BONE IMPLANT AND METHOD FOR PRODUCING SUCH DEVICE - A bone implantable medical device made from a biocompatible material, preferably comprising titania or zirconia, has at least a portion of its surface modified to facilitate improved integration with bone. The implantable device may incorporate a surface infused with osteoinductive agent and/or may incorporate holes loaded with a therapeutic agent. The infused surface and/or the holes may be patterned to determine the distribution of and amount of osteoinductive agent and/or therapeutic agent incorporated. The rate of release or elution profile of the therapeutic agent may be controlled. Methods for producing such a bone implantable medical device are also disclosed and employ the use of ion beam irradiation, preferably gas cluster ion beam irradiation for improving bone integration. | 02-11-2010 |
20100125341 | DEVICE & METHOD FOR RESTORING JOINTS WITH ARTIFICIAL CARTILAGE - An intra-articular device comprises a membrane shaped like a cap having a peripheral geometry similar to that of a head of a bone for a joint to be restored and an open end sized to be applied over the bone proximate the head, so that the open end can be stretched over the head of the bone and held in position on the bone interposed between the head and its corresponding articular component of the joint. The membrane is made of a polyether-urethane-urea material selected to have a property of absorbing the joint's own synovial fluid so as to swell and have a viscoelastic property similar to the body's own articular hyaline cartilage. In a preferred embodiment, the membrane cap is adapted for use on a femoral bone for restoring a hip joint. A related method of installing an intra-articular device as artificial cartilage comprises forming a membrane cap to be applied over the head of the bone of the joint, surgically exposing the head of the bone, installing the membrane cap over the head of the bone, then repositioning the capped head of the bone back in its place in the joint with the membrane interposed as artificial cartilage. | 05-20-2010 |
20100204802 | MEDICAL DEVICE - The present invention provides an implant ( | 08-12-2010 |
20100262258 | BIOMEDICAL MATERIALS - The present invention provides a process for the preparation of a silicate and carbonate co-substituted calcium phosphate material. The process comprises the steps of: forming a silicon and optionally carbon-containing calcium phosphate precipitate by an aqueous precipitation method involving preparing an aqueous solution comprising phosphate ions, silicate ions, calcium ions and optionally carbonate ions, wherein the ratio of Ca/P and of Ca/(P+Si) in the solution is maintained above approximately 1.67; and heating the precipitate in an atmosphere comprising carbon and oxygen to form a silicate and carbonate co-substituted calcium phosphate material. The present invention also provides a synthetic carbonate and silicate co-substituted hydroxyapatite material, as well as a biomedical material. | 10-14-2010 |
20100286790 | IMPLANT AND METHOD FOR COATING AN IMPLANT - The invention relates to an implant made of biocompatible materials, in particular a prosthesis implanted without cement for traumatology and/or orthopedics, which has a main body with an anchoring region which anchors in bone or tissue, with the anchoring region being provided at least partially with a covering layer, the covering layer being formed from a powder using a thermal spraying method, in particular a plasma spraying method. The powder consists essentially of calcium phosphate and comprises antibacterially effective active constituents. | 11-11-2010 |
20110046747 | ANTIBACTERIAL SURFACE AND METHOD OF FABRICATION - This invention involves a plasma treated and controllable release antimicrobial peptide coated titanium alloy for surgical implantation, where the alloy with antimicrobial properties is fabricated using surface techniques without adversely compromising its biocompatibility and original mechanical properties. The surface techniques form antimicrobial layers on the alloy capable of resisting microbial adhesion and proliferation, while allowing mammalian cell adhesion and proliferation when the alloy is implanted to human body. In one embodiment, PIII&D is applied to incorporate ions, electrons, free radicals, atoms or molecules on a titanium alloy substrate. A pressurized hydrothermal treatment can be carried out to establish reactive functional groups for antimicrobial purpose or for connecting the substrate and external antimicrobial molecules. An outermost layer of the titanium alloy includes antibacterial peptides possessing a controllable release mechanism, and is fabricated alone or in an assembly of the aforementioned basal surface layers. The controllable release mechanism is able to withstand long-term deep tissue infection after surgery, and in an embodiment comprises APTES as a linker molecule. | 02-24-2011 |
20110054629 | COMPOSITE IMPLANT HAVING POROUS STRUCTURE FILLED WITH BIODEGRADABLE ALLOY AND METHOD OF MAGNESIUM-BASED MANUFACTURING THE SAME - The present invention provides a composite implant comprising pores of a porous structure filled with a biodegradable magnesium-based alloy. Further, the present invention provides a composite implant which filles pores of the porous structure prepared by a metal, a ceramic or a polymer with a biodegradable magnesium-based alloy. Mechanical properties of the composite implant of the present invention are improved because a magnesium-based alloy filled in its pores increases the strength of a porous structure comprised of a metal, a ceramic or a polymer. Further, it can be expected that the magnesium-based alloy filled in the porous structure is decomposed in a living body, thus increasing bone formation rate. Accordingly bone tissue can be rapidly formed because the composite implant of the present invention has high strength and excellent interfacial force between the composite implant and bone tissue, compared to conventional porous materials. | 03-03-2011 |
20110054630 | ARTIFICIAL BONE COATED WITH APATITE/COLLAGEN COMPOSITE, AND ITS PRODUCTION METHOD - An artificial bone comprising a support coated with an apatite/collagen composite, and a method for producing the artificial bone by immersing the support in a dispersion of the fibrous apatite/collagen composite and drying it. | 03-03-2011 |
20110077746 | Method for cleaning or limiting adhesive. - Methods for cleaning and limiting the extent of adhesives are disclosed. For example, a method for cleaning adhesive near a surgical site in a patient's body comprises the acts of dispensing a magnetic adhesive at a desired location at the surgical site, and applying an external magnetic field that removes a portion of the magnetic adhesive from the body of the patient outside of the desired location. | 03-31-2011 |
20110144761 | BIOCORRODIBLE IMPLANT HAVING A CORROSION-INHIBITING COATING - One embodiment of the invention relates to a biocorrodible implant based on magnesium or a biocorrodible magnesium alloy, whose surface has a corrosion-inhibiting coating. Furthermore, other invention embodiments relate to a respective manufacturing method for the coating. According to an invention embodiment, an implant is provided, comprising | 06-16-2011 |
20110218643 | Method of Forming a Bioactive Coating - A method for the plasma electrolytic oxidation of a bioactive coating onto implant ( | 09-08-2011 |
20110230973 | METHOD FOR BONDING A TANTALUM STRUCTURE TO A COBALT-ALLOY SUBSTRATE - Methods for bonding a porous tantalum structure to a substrate are provided. The method includes placing a compressible or porous interlayer between a porous tantalum structure and a cobalt or cobalt-chromium substrate to form an assembly. The interlayer comprising a metal or metal alloy that has solid state solubility with both the substrate and the porous tantalum structure. Heat and pressure are applied to the assembly to achieve solid state diffusion between the substrate and the interlayer and the between the porous tantalum structure and the interlayer. | 09-22-2011 |
20110307068 | Coating for a CoCrMo Substrate - A coating for a CoCrMo substrate including a first layer located directly on the substrate and including Ta(CoCrMo) | 12-15-2011 |
20120071986 | IMPLANT WITH SURFACE WITH CALCIUM, AND METHODS FOR MODIFYING THE SURFACE OF AN IMPLANT TO PROVIDE SAID SURFACE WITH CALCIUM - The invention relates to an implant for the human or animal body, which on its outer surface comprises at least one calcium salt that is soluble in a polar liquid. The invention also refers to various methods for the preparation of the preceding implant. The calcium ions contained on the surface of the implant provide said surface with four chemically and biologically advantageous properties: hydrophilicity, protection against atmospheric contamination, a pro-coagulant property and a pro-mineralising property. | 03-22-2012 |
20120101589 | PROSTHETIC DEVICES COATED WITH HEATED CROSS-LINKED FIBRIN - The present invention relates to methods of coating prosthetic devices with dried fibrin. Particularly, the present invention relates to methods of coating the surface of prosthetic devices with fibrin and drying the fibrin-coated prosthetic devices at moderately-high temperatures for extended periods of time under low atmospheric pressure to obtain prosthetic devices coated with stable cross-linked fibrin capable of binding cells and thereby capable of integrating into tissues. | 04-26-2012 |
20130030544 | Implant and method for producing an implant - An implant is provided with a main body ( | 01-31-2013 |
20130096691 | HYDROPHILIC INTERPENETRATING POLYMER NETWORKS DERIVED FROM HYDROPHOBIC POLYMERS - A composition of matter comprising a water-swellable IPN or semi-IPN including a hydrophobic thermoset or thermoplastic polymer and an ionic polymer, articles made from such composition and methods of using such articles. The invention also includes a process for producing a water-swellable IPN or semi-IPN from a hydrophobic thermoset or thermoplastic polymer including the steps of placing an ionizable monomer solution in contact with a solid form of the hydrophobic thermoset or thermoplastic polymer; diffusing the ionizable monomer solution into the hydrophobic thermoset or thermoplastic polymer; and polymerizing the ionizable monomers to form a ionic polymer inside the hydrophobic thermoset or thermoplastic polymer, thereby forming the IPN or semi-IPN. | 04-18-2013 |
20130150978 | Bone implant comprising a magnesium-containing metallic material with reduced corrosion rate, and methods and kit for producing the bone implant - The invention relates to a bone implant which comprises a magnesium-containing metallic material having a reduced corrosion rate and inorganic bone cement, and to methods and a kit for producing the bone implant. With a method according to the invention, it is possible to obtain a bone implant which comprises inorganic bone cement and a magnesium-containing metallic material with a corrosion-inhibiting coating which contains magnesium-ammonium phosphates. In the method according to the invention, a magnesium-containing metallic material, of which the surface has a magnesium oxide layer and/or a magnesium salt layer, is combined with inorganic bone cement in order to generate a solid composite material that comprises the inorganic bone cement and the magnesium-containing metallic material. The inorganic bone cement contains inorganic powder constituents, which set in the presence of water to form a solid, and water-soluble phosphate-ion-containing salts, preferably water-soluble phosphate-ion-containing and ammonium-ion-containing salts. According to the invention, the magnesium-containing metallic material is brought into contact with water before and/or during the combination with the inorganic bone cement in the presence pt of water-soluble ammonium-ion-containing and phosphate-ion-containing salts. Moreover, the inorganic bone cement is set by being brought into contact with water. | 06-13-2013 |
20130190888 | Implant Having a Multilayered Coating and a Process for Preparing Thereof - The present invention relates to an implant having a multilayered coating comprising a porous titanium-based layer on the implant, an optional interface titania layer on and/or in the porous titanium-based layer and a bioactive glass layer on and/or in the porous structure formed by the titanium-based and titania layer(s); as well as to a process for preparing an implant having a multilayered coating. | 07-25-2013 |
20140324186 | Medical Implants with Enhanced Osseointegration - Medical implants with non-equilibrium surface structures are disclosed. The surface treatment of the implants greatly enhances osseointegration, reduces time to recovery following implant surgery, reduces surgery-related infections, and improves outcomes. The implants, including dental implants and other implants for insertion into or attachment to bone, are applicable to treatment of a wide variety of medical conditions. The methods of altering the surface properties of medical implants include exposure of a crystalline surface material, such as metal or ceramic, to a short burst of high thermal energy or shock, resulting in the introduction of a non-equilibrium concentration of crystal lattice defects in a surface layer. | 10-30-2014 |
20150359635 | MEDICAL DEVICE AND SURFACE MODIFICATION METHOD FOR MEDICAL DEVICE - The invention provides a medical device in which a metallic porous body is joined to at least a part of a surface of the main body of a medical device, and a surface modification method for the medical device. The metallic porous body is formed in multilayers. | 12-17-2015 |